He aha ka Antihemophilic Factor (Recombinant, PEGylated) - Aucl? Nā hoʻohana, nā hopena ʻaoʻao, & alakaʻi lapaʻau

ʻO Antihemophilic Factor (Recombinant, PEGylated) - Aucl he mana i hana ʻia i loko o ka hale hana o kahi protein hoʻopaʻa koko e kōkua ana i ka poʻe me ka hemophilia A e hooki i ke kahe koko. Hoʻololi kēia lāʻau i ka clotting factor VIII i nalowale a hewa paha e pono ai kou kino e hana pono i nā clots koko.

Inā loaʻa iā ʻoe a i ʻole kekahi āu e mālama nei i ka hemophilia A, hiki i kēia lāʻau lapaʻau ke lilo i ʻāpana koʻikoʻi o ka mālama ʻana i ke kūlana. Hana ia ma ka hāʻawi ʻana i kou kino i ka clotting factor i nalowale, e kōkua ana i ka pale ʻana i nā hanana kahe koko weliweli a hiki iā ʻoe ke ola i ke ola maʻamau.

He aha ka Antihemophilic Factor (Recombinant, PEGylated) - Aucl?

ʻO kēia lāʻau lapaʻau he mana synthetic o ka factor VIII, kahi protein e pono ai kou koko e clot pono. ʻO ka ʻāpana

Hiki paha iā ʻoe ke ʻike e pau koke ana ke kahe ʻana o ke koko ma hope o ka loaʻa ʻana o kēia lāʻau lapaʻau, hiki ke lawe mai i ke kōkua nui inā ua pilikia ʻoe i kahi hanana kahe koko. Nui ka poʻe e hōʻike ana i ka manaʻoʻiʻo nui i kā lākou hana i kēlā me kēia lā me ka ʻike ʻana he palekana kēia iā lākou.

He aha ke kumu e pono ai kēia lāʻau lapaʻau?

ʻO Hemophilia A ke kūlana mua e pono ai kēia lāʻau lapaʻau. ʻO kēia maʻi genetic ke ʻano ʻaʻole hana kou kino i ka protein factor VIII, a i ʻole ʻaʻole hana pono ka factor VIII e kōkua i kou koko e paʻa.

Hana ʻia ke kūlana ma muli o nā loli i loko o kahi gene kikoʻī e hāʻawi ana i nā ʻōlelo aʻoaʻo no ka hana ʻana i ka factor VIII. Mai ka wahi o kēia gene ma ka chromosome X, ʻoi aku ka nui o ka hemophilia A i nā kāne ma mua o nā wahine.

Eia nā kumu nui e pono ai kekahi i kēia lāʻau lapaʻau:

• Hemophilia A i hoʻoilina ʻia mai nā lālā o ka ʻohana
• Nā loli genetic spontaneous e hoʻoulu ai i ka hemahema o ka factor VIII
• Nā hanana kahe koko koʻikoʻi e pono ai ka hoʻololi koke ʻana o ka clotting factor
• Lapaʻau pale e hōʻemi i ka pilikia o nā pilikia kahe koko
• Hoʻomākaukau no ke ʻoki a i ʻole nā kaʻina hana niho

ʻO ka hoʻomaopopo ʻana i kāu kūlana kikoʻī e kōkua i kāu hui mālama ola e hoʻoholo i ke ala lapaʻau maikaʻi loa no ʻoe. E pili ana ka paʻakikī o kāu hemophilia i ka pinepine o kou pono i kēia lāʻau lapaʻau.

He aha nā kūlana e mālama ai kēia lāʻau lapaʻau?

Mālama mua kēia lāʻau lapaʻau i ka hemophilia A, akā hoʻohana ʻia ia ma nā ʻano like ʻole e pili ana i kāu mau pono kikoʻī. Hiki i kāu kauka ke kuhikuhi iā ia no ka pale ʻana a i ʻole ka mālama ʻana i nā hanana kahe koko.

Hoʻoponopono ka lāʻau lapaʻau i kekahi mau ʻano o ka mālama ʻana i ka hemophilia A:

• Hemophilia A koʻikoʻi me nā pae factor VIII ma lalo o 1% o ka maʻamau
• Hemophilia A waena me nā pae factor VIII ma waena o 1-5% o ka maʻamau
• Hemophilia A maʻalahi me nā pae factor VIII ma waena o 5-40% o ka maʻamau
• Nā hanana koko i loko o nā hono, nā ʻiʻo, a i ʻole nā ʻōkana o loko
• Lapaʻau prophylactic e pale ai i ke kahe koko
• Hoʻokele perioperative no nā ʻoki a me nā kaʻina hana

E hana pū kāu mea mālama ola me ʻoe e hoʻoholo inā pono ʻoe i nā infusions prophylactic maʻamau a i ʻole ka lapaʻau wale nō ke hiki mai ke kahe koko. Aia kēia hoʻoholo i kāu mōʻaukala kahe koko a me nā kumu ola.

Hiki i nā hanana kahe koko ke hoʻoponopono me ka ʻole o kēia lāʻau lapaʻau?

No ka poʻe me ka hemophilia A, ʻaʻole hiki i nā hanana kahe koko ke hoʻoponopono palekana iā lākou iho me ka ʻole o ka hoʻololi ʻana i ka clotting factor. ʻAʻole i loaʻa i kou kino ka protein pono e hana i nā clots koko paʻa.

Hiki i nā ʻoki liʻiliʻi a i ʻole nā ʻōpala ke hoʻōki i ke kahe koko, akā lōʻihi ka lōʻihi o kēia kaʻina hana ma mua o ka maʻamau a hiki ke pilikia. ʻAʻole pinepine ke kahe koko o loko, ʻoiai i loko o nā hono a i ʻole nā ʻiʻo, e kū me ka ʻole o ka lapaʻau kūpono a hiki ke hōʻino mau.

ʻO ke kali ʻana i ke kahe koko e kū maoli e hoʻokau iā ʻoe i ka pilikia no nā pilikia koʻikoʻi e like me ka pōʻino o ka hui, ka nāwaliwali o ka ʻiʻo, a i ʻole ke kahe koko o loko e hoʻoweliweli ana i ke ola. ʻO ia ke kumu he mea nui ka lapaʻau wikiwiki me ka hoʻololi ʻana i ka factor VIII no kou olakino a me kou palekana.

Pehea e hāʻawi ʻia ai kēia lāʻau lapaʻau ma ke ʻano he lapaʻau?

Hāʻawi ʻia kēia lāʻau lapaʻau ma o ka intravenous (IV) injection pololei i loko o kou vein. He mau minuke wale nō ke kaʻina hana a hiki ke hana ʻia i loko o kahi haukapila, keʻena lapaʻau, a i ʻole ma ka home ke aʻo pono ʻoe.

E helu kāu mea mālama ola i kāu mahele kikoʻī e pili ana i kou kaumaha, ka paʻakikī o kou hemophilia, a inā paha e mālama ana ʻoe i ke kahe ʻana o ke koko a i ʻole e pale ana i nā hanana e hiki mai ana. Hele mai ka lāʻau lapaʻau ma ke ʻano he pauka e pono e hui pū ʻia me ka wai sterile ma mua o ka hoʻokomo ʻana.

Eia ke ʻano o ke kaʻina hana lapaʻau:

1. Hoʻomākaukau kāu mea mālama ola i ka lāʻau lapaʻau ma ka hui ʻana i ka pauka me ka wai sterile
2. Huli lākou i kahi vein kūpono, maʻamau i kou lima a i ʻole ka lima
3. Hoʻokomo mālie ʻia ka lāʻau lapaʻau i loko o kekahi mau minuke
4. E nānā pōkole ʻia ʻoe e hōʻoia e ʻae maikaʻi ʻoe i ka lapaʻau
5. Uhi ʻia ke kahua injection me kahi bandage liʻiliʻi

Nui ka poʻe e aʻo e hoʻokele iā lākou iho i kēia lāʻau lapaʻau ma ka home, e hāʻawi ana i ke kūʻokoʻa a me ke kūʻokoʻa. E hāʻawi kāu hui mālama ola i ka hoʻomaʻamaʻa piha inā kūpono ka lapaʻau home no kou kūlana.

I ka manawa hea wau e ʻimi ai i ka lāʻau lapaʻau i ka wā e hoʻohana ana i kēia lāʻau lapaʻau?

Pono ʻoe e hoʻokaʻaʻike koke i kāu mea mālama ola inā ʻike ʻoe i nā hōʻailona o ka hopena maʻi, e like me ka pilikia o ka hanu ʻana, ka pehu ʻana o kou maka a i ʻole ka ʻāʻī, a i ʻole nā ​​hopena ʻili koʻikoʻi. Pono kēia mau hōʻailona, ​​ʻoiai he kakaikahi, i ka lāʻau lapaʻau koke.

E ʻimi i ka mālama olakino wikiwiki inā e ulu ana ʻoe i ke kahe ʻana o ke koko koʻikoʻi ʻaʻole e pane i kāu mahele lapaʻau maʻamau, a i ʻole inā ʻike ʻoe i nā ʻano kahe koko maʻamau. Hiki paha i kēia ke hōʻike nei e hoʻomohala ana kou kino i nā antibodies e kūʻē i ka lāʻau lapaʻau.

Eia nā kūlana kikoʻī e pono ai ka lāʻau lapaʻau koke:

• Nā hopena maʻi maʻi koʻikoʻi me ka pilikia o ka hanu ʻana a i ʻole ka ʻai ʻana
• Ke kahe mau ʻana o ke koko me ka mālama kūpono ʻana i ka factor VIII
• Nā hōʻailona o nā koko koko e like me ka ʻeha o ka umauma, ka hanu ʻana, a i ʻole ka pehu ʻana o ka wāwae
• Nā ʻeha a i ʻole ke kahe ʻana o ke koko i ʻike ʻia he nui
• Ka fiva, nā anu, a i ʻole nā hōʻailona o ka maʻi ma kahi i hoʻokomo ʻia ai ka lāʻau
• Ke poʻo nui, nā loli o ka ʻike, a i ʻole nā hōʻailona neurological

Mai kānalua e launa pū me kāu hui mālama ola no nā hopohopo e pili ana i kāu lapaʻau. Aia lākou e kōkua iā ʻoe e mālama i kou maʻi me ka palekana a me ka pono.

He aha nā mea pilikia no ka pono o kēia lāʻau?

ʻO ka mea pilikia nui no ka pono o kēia lāʻau, ʻo ia ka loaʻa ʻana o ka hemophilia A, he maʻi genetic i hoʻoilina ʻia. Inā he mau lālā ʻohana kou me ka hemophilia A, aia paha ʻoe i ka pilikia o ka loaʻa ʻana o ka maʻi iā ʻoe iho.

No ka mea, ua pili ka hemophilia A i ka chromosome X, ʻoi aku ka nui o nā kāne e pili ana no ka mea hoʻokahi wale nō kā lākou chromosome X. Hiki i nā wāhine ke lawe a loaʻa paha nā hōʻailona maʻalahi, akā ʻaʻole paha lākou e loaʻa i ka hemophilia A koʻikoʻi.

Nui nā mea e pili ana i kou hiki ke pono i kēia lapaʻau:

• Ka mōʻaukala ʻohana o ka hemophilia A a i ʻole nā maʻi kahe koko ʻē aʻe
• He kāne (ma muli o ke ʻano hoʻoilina X-linked)
• He makuahine kāu e lawe ana i ka gene hemophilia A
• Nā hanana kahe koko i hala i koi i ka hana lapaʻau
• Ke komo ʻana i nā hana me ka pilikia ʻeha kiʻekiʻe
• Pono no nā hana ʻoki a i ʻole nā hana niho

Inā he mau mea pilikia kou no ka hemophilia A, hiki i ka ʻōlelo aʻoaʻo genetic ke kōkua iā ʻoe e hoʻomaopopo maikaʻi i kou kūlana. Hiki i ka hōʻailona mua a me ka hoʻolālā lapaʻau kūpono ke hoʻomaikaʻi nui i kou maikaʻi o ke ola.

He aha nā pilikia hiki ke loaʻa i kēia lapaʻau?

ʻOiai he palekana a maikaʻi kēia lāʻau lapaʻau, e like me nā lāʻau lapaʻau a pau, hiki i kekahi manawa ke hana i nā hopena ʻaoʻao a i ʻole nā pilikia. ʻO ka hapa nui o nā kānaka e ʻae maikaʻi i ka lāʻau lapaʻau, akā he mea nui e ʻike i nā pilikia e hiki mai ana.

ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a he manawa pōkole, me ke poʻo, ka ʻūlū, a i ʻole ka nausea. Hoʻoponopono maʻamau kēia mau mea iā lākou iho i loko o kekahi mau hola o ka lāʻau lapaʻau.

Hiki ke loaʻa nā pilikia koʻikoʻi, ʻoiai ʻaʻole maʻamau lākou:

• Nā hopena maʻi mai ka huhū ʻili maʻalahi a hiki i ka anaphylaxis koʻikoʻi
• Ka hoʻomohala ʻana i nā mea pale (nā antibodies e hoʻemi ai i ka maikaʻi o ka lāʻau lapaʻau)
• Nā koko koko, ʻoi aku hoʻi me nā kiʻekiʻe kiʻekiʻe a i ʻole ka hoʻohana pinepine ʻana
• Nā hopena o ka pūnaewele injection e like me ka ʻeha, ka pehu, a i ʻole ka maʻi
• Nā loli i ka puʻuwai a i ʻole ke koko i ka wā o ka infusion
• Nā hihia kakaʻikahi o nā pilikia o ka puʻupaʻa a i ʻole nā loli hana ate

Mālama pono kāu hui mālama ola iā ʻoe no kēia mau pilikia a hoʻoponopono i kāu hoʻolālā lapaʻau e like me ka mea e pono ai. Kōkua nā hoʻokolohua koko maʻamau i ka ʻike ʻana i nā pilikia i ka wā mua i hiki ke hoʻoponopono koke ʻia.

He kūpono anei kēia lāʻau lapaʻau no nā ʻano hemophilia a pau?

Hoʻolālā ʻia kēia lāʻau lapaʻau no ka hemophilia A a ʻaʻole kūpono no nā ʻano hemophilia ʻē aʻe. Hoʻopili ka Hemophilia A i ka hemahema o ka factor VIII, ʻo ia ka mea a kēia lāʻau lapaʻau e pani ai.

Inā he hemophilia B kāu (i kapa ʻia hoʻi ʻo ka maʻi Kalikimaka), pono ʻoe i kahi lāʻau lapaʻau ʻē aʻe i loaʻa ka factor IX ma kahi o ka factor VIII. ʻAʻole e kōkua ka hoʻohana ʻana i ke ʻano hewa o ka clotting factor i kāu mau hanana koko.

E hōʻoia kāu kauka i kāu ʻano hemophilia ma o nā hoʻokolohua koko ma mua o ke kau ʻana i kēia lāʻau lapaʻau. E hōʻoia kēia e loaʻa iā ʻoe ka lāʻau lapaʻau kūpono loa no kou maʻi.

No ke aha e hiki ai ke kuhi hewa ʻia kēia lāʻau lapaʻau?

Hiki ke huikau ʻia kēia lāʻau lapaʻau me nā huahana clotting factor ʻē aʻe, ʻo ia hoʻi nā ʻano ʻē aʻe o ka factor VIII ʻaʻole i loaʻa ka uhi PEGylated. ʻOiai e lawelawe ana kēia mau lāʻau lapaʻau i nā kumu like, pono paha lākou i nā papa hana ʻokoʻa.

Hiki i kekahi poʻe ke huikau i kēia lapaʻau me nā huahana factor IX i hoʻohana ʻia no ka hemophilia B, a i ʻole me nā huahana koko ʻē aʻe e like me ka plasma paʻa hou. Eia naʻe, hana ʻokoʻa kēlā me kēia o kēia mau lapaʻau a hoʻohana ʻia no nā kūlana kikoʻī.

He mea nui e hōʻoia mau e loaʻa ana iā ʻoe ka lāʻau lapaʻau kūpono no kāu ʻano hemophilia. E hōʻoia kāu mea mālama ola e loaʻa iā ʻoe ka lāʻau lapaʻau kūpono, akā hiki iā ʻoe ke kōkua ma ka nīnau ʻana i nā nīnau a me ka noho ʻike e pili ana i kāu mau lāʻau lapaʻau.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Antihemophilic Factor (Recombinant, PEGylated) - Aucl

Pehea ka lōʻihi o ka lāʻau lapaʻau e noho pono ai i loko o koʻu kino?

Kōkua ka uhi PEGylated i kēia lāʻau lapaʻau e noho i loko o kou kahe koko no ka lōʻihi ma mua o nā huahana factor VIII kuʻuna. Mālama ka hapa nui o nā kānaka i nā pae pale no 2-3 mau lā ma hope o ka injection, ʻoiai e ʻokoʻa kēia ma muli o nā mea pilikino e like me kāu metabolism a me ka pae hana.

Hiki iaʻu ke hele i ka wā e hoʻohana ana i kēia lāʻau lapaʻau?

ʻAe, hiki iā ʻoe ke hele i ka wā e hoʻohana ana i kēia lāʻau lapaʻau, akā pono ʻoe e hoʻolālā i mua. Hiki i kāu mea mālama ola ke kōkua iā ʻoe e hoʻonohonoho i nā lako lāʻau lapaʻau a hāʻawi i nā palapala no ka palekana o ke kahua mokulele. Nui ka poʻe e hele maikaʻi ana i ka honua i ka wā e mālama ana i kā lākou hemophilia.

Pono anei au i kēia lāʻau lapaʻau no ke koena o koʻu ola?

He maʻi ola ʻo Hemophilia A, no laila pono ka hapa nui o nā kānaka i ka mālama mau ʻana me ka hoʻololi ʻana i ka clotting factor. Eia naʻe, hiki ke loli nā ala lapaʻau i ka manawa ma muli o ka noiʻi hou a me kāu mau pono pilikino. E loiloi mau kāu hui mālama ola i kāu hoʻolālā lapaʻau.

Aia kekahi mau hana e pono ai iaʻu e pale aku i ka wā e hoʻohana ana i kēia lāʻau lapaʻau?

Hiki i kēia lāʻau lapaʻau ke ʻae iā ʻoe e komo i nā hana hou aku me ka palekana ma ka hāʻawi ʻana i ka pale koko maikaʻi aʻe. Eia naʻe, pono nō ʻoe e pale i nā hana pilikia kiʻekiʻe e hiki ke hōʻeha nui. Hiki i kāu mea mālama ola ke aʻo iā ʻoe e pili ana i nā hoʻololi hana e pili ana i kāu kūlana.

Hiki i kēia lāʻau lapaʻau ke launa pū me nā lāʻau ʻē aʻe aʻu e lawe nei?

He liʻiliʻi nā pilina lāʻau lapaʻau o kēia lāʻau lapaʻau, akā pono ʻoe e haʻi mau i kāu poʻe mālama ola e pili ana i nā lāʻau lapaʻau a me nā mea hoʻohui āu e lawe nei. Pono paha kekahi mau lāʻau lapaʻau e pili ana i ka hoʻopaʻa ʻana i ke koko i nā hoʻoponopono ʻana i ka dosis ke hoʻohana pū ʻia me ka pani ʻana o ka factor VIII.