He aha ka Antihemophilic Factor VIII a me von Willebrand Factor (Alae Intravenous)? Nā Hōʻailona, ​​Nā Kumu, & Lapaʻau Home

ʻO Antihemophilic Factor VIII a me von Willebrand Factor he lāʻau lapaʻau e hoʻopakele ai i ke ola i hāʻawi ʻia ma o ka IV e kōkua i kou koko e paʻa pono. Hoʻololi kēia lapaʻau i nā protein clotting nalowale a hewa paha i ka poʻe me kekahi mau maʻi koko, e kōkua ana i ka pale ʻana i nā hanana koko weliweli.

Hana maʻamau kou kino i kēia mau protein e hoʻōki i ke koko ke loaʻa ʻoe i ka ʻeha. Ke hana ʻole kēia mau protein a i ʻole ka nalowale, hiki i nā ʻoki liʻiliʻi ke alakaʻi i nā pilikia koko koʻikoʻi ʻaʻole e kū ma ko lākou iho.

He aha ka Antihemophilic Factor VIII a me von Willebrand Factor?

Aia i loko o kēia lāʻau lapaʻau ʻelua mau protein clotting koko nui e hana pū ana e like me ka hui. Hana ʻo Factor VIII ma ke ʻano he protein kōkua e wikiwiki i ke kaʻina clotting, ʻoiai ʻo von Willebrand Factor e kōkua i kāu mau platelets koko e pili pū e hana i nā clots.

Hana ʻia ka lāʻau lapaʻau mai ke koko plasma kanaka i hāʻawi ʻia i hana ʻia a hoʻomaʻemaʻe ʻia. Hāʻawi pololei ʻia i loko o kou kahe koko ma o ka IV, maʻamau i kahi haukapila a i ʻole ke keʻena lapaʻau kahi e hiki ai i nā poʻe loea lapaʻau ke nānā pono iā ʻoe.

Hoʻolālā ʻia kēia lapaʻau no ka poʻe ʻaʻole i hana i ka nui o kēia mau mea clotting maoli. Hoʻololi ʻo ia i ka mea e nalowale ana i kou kino, e kōkua ana i ka hoʻihoʻi ʻana i ka hana clotting koko maʻamau.

Pehea ke ʻano o ka loaʻa ʻana o kēia lapaʻau?

Manaʻo ka hapa nui o ka poʻe i ka hoʻokomo ʻana i ka IV ma ke ʻano he piniki liʻiliʻi, e like me ka loaʻa ʻana o ke koko no ka hana lab. Ke hoʻomaka ka lāʻau lapaʻau e kahe, ʻaʻole ʻoe e manaʻo i kekahi mea maʻamau i loko o kou kahe koko.

I ka wā o ka infusion, hiki iā ʻoe ke ʻike i kekahi mau hopena ʻaoʻao maʻalahi. Hiki i kēia ke komo i kahi poʻo liʻiliʻi, ka manaʻo mehana a i ʻole ka ʻulaʻula, a i ʻole kekahi nausea. Hele maʻamau kēia mau manaʻo a ʻaʻole ia he kumu e hopohopo ai.

Hōʻike kekahi poʻe i ka manaʻolana a i ʻole ka hōʻoluʻolu ma hope o ka mālama ʻana, ʻoiai inā e kū ana lākou i nā pilikia koko e mau ana. E nānā pono kāu hui lapaʻau iā ʻoe i ka wā a ma hope o ka hoʻokomo ʻana e hōʻoia e pane maikaʻi ana ʻoe.

He aha ke kumu o ka pono no kēia lapaʻau?

No ka pono o kēia lāʻau lapaʻau mai nā maʻi koko i hoʻoilina ʻia e pili ana i ke ʻano o ka hoʻopaʻa ʻana o kou koko. Hele kēia mau kūlana i loko o nā ʻohana a aia mai ka wā hānau, ʻoiai ʻaʻole paha e ʻike ʻia nā hōʻailona a hiki i ka wā ma hope o ke ola.

Eia nā kūlana nui e koi ai i kēia lapaʻau:

• Hemophilia A - i ka wā ʻaʻole hana kou kino i ka protein Factor VIII
• maʻi von Willebrand - i ka wā ʻaʻole hana pono kāu von Willebrand Factor a i ʻole e nalowale ana
• ʻO ka hemahema o ka Factor VIII a me von Willebrand Factor - he maʻi kakaʻikahi e pili ana i nā protein ʻelua
• Nā maʻi koko i loaʻa - i kekahi manawa e ulu ana ma hope o ke ola ma muli o nā maʻi olakino ʻē aʻe

ʻAʻole kēia mau mea he mau maʻi hiki iā ʻoe ke loaʻa mai kekahi kanaka a i ʻole e ulu mai nā koho ola. Hana lākou ma muli o nā loli i kāu genes e pili ana i ke ʻano o ka hana ʻana o kou kino i nā protein clotting.

He aha kēia lapaʻau he hōʻailona a hōʻailona paha o?

ʻO ka pono o kēia lapaʻau e hōʻike ana he maʻi koko kou e pili ana i ka hiki ʻana o kou koko ke hoʻopaʻa maʻamau. ʻAʻole kēia he hōʻailona iā ia iho, akā he lapaʻau lapaʻau no nā kūlana ma lalo.

ʻO nā kūlana ma lalo e pili ana i kēia lapaʻau e pili ana i nā ʻano maʻi koko:

• Hemophilia A - ka maʻi kahe koko koʻikoʻi maʻamau, e pili ana i nā kāne
• Maʻi von Willebrand Type 2N - kahi e hiki ʻole ai i ka von Willebrand Factor ke lawe pono i ka Factor VIII
• Maʻi von Willebrand Type 3 - ke ʻano koʻikoʻi loa, kahi e haʻahaʻa loa ai nā protein ʻelua
• Hemophilia i loaʻa - kahi maʻi kakaʻikahi kahi e hoʻouka ai kou ʻōnaehana pale i kāu mau mea hoʻopaʻa koko ponoʻī
• Nā kūlana hemahema hui pū - nā kūlana kakaʻikahi loa e pili ana i nā protein hoʻopaʻa koko he nui

E hana kāu kauka i nā hoʻokolohua koko kūikawā e hoʻoholo pono i ke ʻano o kou maʻi. Kōkua kēia iā lākou e koho i ka lāʻau lapaʻau kūpono a me ka dosage no kou kūlana.

Hiki i nā maʻi kahe koko ke hoʻomaikaʻi iā lākou iho?

ʻO ka mea pōʻino, ʻaʻole e hele wale nā maʻi kahe koko i hoʻoilina iā lākou iho no ka mea ua hana ʻia lākou e nā loli genetic. E hoʻomau ana kou kino i ka pilikia i ka hana ʻana a i ʻole ka hoʻohana ʻana i kēia mau protein hoʻopaʻa koko me ka ʻole o ka lāʻau lapaʻau.

Eia naʻe, ʻo ka nūhou maikaʻi, me ka lāʻau lapaʻau kūpono, hiki i ka hapa nui o ka poʻe me nā maʻi kahe koko ke ola i ke ola maʻamau a ikaika. Kōkua ka lāʻau lapaʻau maʻamau i ka pale ʻana i nā hanana kahe koko koʻikoʻi a pale i kou mau hono a me nā ʻōkana mai ka pōʻino.

ʻAʻole pono paha kekahi poʻe me nā ʻano maʻalahi o kēia mau maʻi i ka lāʻau lapaʻau i nā manawa a pau. E hana kāu kauka me ʻoe e hana i kahi hoʻolālā lapaʻau e kūpono i kāu mau pono a me ke ʻano o ke ola.

Pehea e hiki ai ke mālama ʻia nā maʻi kahe koko ma ka home?

ʻOiai ʻaʻole hiki iā ʻoe ke mālama i ke kūlana kumu ma ka home, aia nā ala nui e pale ai iā ʻoe iho a mālama i kou olakino ma waena o nā lāʻau lapaʻau.

Eia nā hoʻolālā hoʻokele home nui e hiki ke kōkua iā ʻoe e palekana:

• E hōʻalo i nā hana me ka pilikia kiʻekiʻe o ka ʻeha, e like me nā haʻuki pili a i ʻole ka hoʻohana ʻana i nā mea hana ʻoi me ka mālama ʻole.
• E mālama i kahi pahu kōkua mua i lako pono a e ʻike pehea e hoʻopili ai i ke kaomi kūpono i nā ʻeha e kahe ana ke koko.
• E ʻaʻahu i nā mea nani e hōʻike ana i ka lāʻau lapaʻau e hōʻike ana i kou maʻi kahe koko.
• E lawe i nā lāʻau i kauoha ʻia e like me ke kuhikuhi ʻia, me nā lāʻau pale.
• E launa mau me kāu hui mālama ola a e hōʻike i nā kahe koko ʻano ʻē.
• E mālama i ka maʻemaʻe o nā niho e pale ai i ke kahe ʻana o nā ʻāʻī a me nā kaʻina hana niho.

He mea nui nō hoʻi e haʻi i kāu poʻe lawelawe mālama ola a pau e pili ana i kāu maʻi kahe koko ma mua o nā kaʻina hana. Aia kēia i nā kauka niho, nā kauka lapaʻau, a me kāu kauka mālama mua no ka mālama maʻamau.

He aha ka lāʻau lapaʻau no nā maʻi kahe koko?

Ke nānā nei ka lāʻau lapaʻau i ka hoʻololi ʻana i nā mea clotting i nalowale a me ka pale ʻana i nā hanana kahe koko. E hoʻopilikino ʻia kāu hoʻolālā lapaʻau i kou kūlana a me ke koʻikoʻi.

ʻO nā koho lapaʻau nui e komo pū ana:

1. Lāʻau lapaʻau hoʻololi i ka mea - nā infusions maʻamau o nā protein clotting i nalowale.
2. Lāʻau lapaʻau prophylactic - nā infusions pale e mālama i nā pae clotting factor kūpono.
3. Lāʻau lapaʻau ma ke koi - nā infusions i hāʻawi ʻia i ka wā e kahe ana ke koko a i ʻole ma mua o nā kaʻina hana.
4. Desmopressin (DDAVP) - he lāʻau lapaʻau e hiki ke hoʻoikaika i ka hana ʻana o kou kino iho i kekahi mau hihia.
5. Nā lāʻau antifibrinolytic - nā lāʻau e kōkua i ka hoʻopaʻa ʻana i nā clots koko ke hana lākou.

E nānā kāu kauka i kāu pane ʻana i ka lāʻau lapaʻau me nā hoʻokolohua koko maʻamau. E hoʻoponopono lākou i kāu hoʻolālā lapaʻau e like me ka mea e pono ai e hōʻoia e loaʻa ana iā ʻoe ka pale maikaʻi loa i ke kahe koko.

I ka manawa hea wau e ʻike ai i ke kauka no nā pilikia kahe koko?

Pono ʻoe e launa koke me kāu hui mālama ola inā loaʻa iā ʻoe kekahi kahe koko koʻikoʻi ʻaʻole e pau me nā hana kōkua mua maʻamau. He mea nui kēia inā he maʻi kahe koko kou.

E ʻimi i ka lāʻau lapaʻau pilikia no kēia mau kūlana:

• Nā ʻeha poʻo a i ʻole nā ʻeha poʻo nui e hōʻike ana i ke kahe koko i loko
• Ke kahe koko nui e komo ana i nā pākuʻi a ʻaʻole e pau ma hope o 15 mau minuke o ke kaomi pololei
• ʻEha hui a me ka pehu e hōʻike ana i ke kahe koko i loko
• ʻO ka ʻehaʻeha maʻamau e ʻike ʻia me ka ʻole o ka ʻeha a i ʻole e ulu wikiwiki
• Ke koko i loko o ka mimi, ka ʻōpala, a i ʻole ka luaʻi
• ʻEha ʻōpū a i ʻole ke kua nui e hōʻike ana i ke kahe koko i loko

Mai kali e ʻike inā pau ke kahe koko iā ia iho. Me nā maʻi kahe koko, ʻoi aku ka maikaʻi o ka ʻimi ʻana i ke kōkua ma mua o ka lohi, no ka mea, pale ka lāʻau lapaʻau mua i nā pilikia.

He aha nā mea pilikia no ka hoʻomohala ʻana i nā maʻi kahe koko?

Hoʻoilina ʻia ka hapa nui o nā maʻi kahe koko, ʻo ia hoʻi, ua hala lākou ma nā ʻohana. ʻO ka mea pilikia nui ka loaʻa ʻana o nā mākua a i ʻole nā ​​ʻohana me kēia mau kūlana.

ʻO nā mea pilikia nui e pili ana:

• ʻO ka mōʻaukala ʻohana o nā maʻi kahe koko - ka mea wānana ikaika loa
• He kāne - no ka hemophilia A, i lawe ʻia ma ka chromosome X
• Loaʻa nā mākua i nā mea lawe o nā genes maʻi kahe koko
• ʻO kekahi mau ʻano lāhui i loaʻa nā helu kiʻekiʻe o nā maʻi kahe koko
• ʻO ka makahiki kiʻekiʻe - no nā maʻi kahe koko i loaʻa i ka wā ma hope o ke ola
• Nā kūlana autoimmune - hiki ke hoʻoulu i nā maʻi kahe koko i loaʻa

Inā he mōʻaukala ʻohana kou o nā maʻi kahe koko, hiki i ka ʻōlelo aʻoaʻo genetic ke kōkua iā ʻoe e hoʻomaopopo i kāu mau pilikia. He mea nui kēia inā ʻoe e hoʻolālā nei e loaʻa nā keiki.

He aha nā pilikia hiki ke loaʻa i nā maʻi kahe koko i mālama ʻole ʻia?

Inā ʻaʻole mālama pono ʻia, hiki i nā maʻi koko ke alakaʻi i nā pilikia nui e pili ana i kou maikaʻi o ke ola a me ke olakino holoʻokoʻa. ʻO ka lono maikaʻi, hiki ke pale ʻia ka hapa nui o kēia mau pilikia me ka mālama olakino kūpono.

ʻO nā pilikia hiki ke loaʻa:

• ʻO ka pōʻino o nā hui mai ke kahe koko pinepine ʻana i loko o nā hui, e alakaʻi ana i ka arthritis a me ka neʻe palena
• ʻO ke kahe koko ʻana o nā ʻiʻo e hiki ke hana i ka ʻeha, ka pehu, a me ka pōʻino mau
• ʻO ke kahe koko ʻana i loko o ke ola, ʻoi aku hoʻi i ka lolo a i ʻole ka ʻōnaehana digestive
• ʻO ka anemia koʻikoʻi mai ka nalowale koko mau
• Nā pilikia i ka wā o ke ʻoki a i ʻole nā hana niho
• Nā hopena noʻonoʻo mai ka noho ʻana me ka makaʻu i nā hanana kahe koko

Me ka mālama hou, hiki i ka hapa nui o ka poʻe me nā maʻi koko ke pale loa i kēia mau pilikia. ʻO ka mālama olakino maʻamau a me ka hahai ʻana i kāu hoʻolālā lapaʻau ke kī i ka noho olakino a me ka hana.

He maikaʻi a he ʻino paha ka lapaʻau ʻo Factor VIII a me von Willebrand Factor no nā maʻi koko?

He maikaʻi maoli kēia lapaʻau no ka poʻe me nā maʻi koko - he ola pinepine ia a hiki ke hoʻomaikaʻi nui i ka maikaʻi o ke ola. ʻOi aku ka maikaʻi ma mua o nā pilikia no ka poʻe e pono ai kēia lāʻau.

Hāʻawi ka lapaʻau i nā pōmaikaʻi koke ma ka hoʻihoʻi ʻana i ka hiki o kou koko ke hoʻopaʻa pono. ʻO ia hoʻi, ʻoi aku ka liʻiliʻi o nā hanana kahe koko, ʻoi aku ka liʻiliʻi o ka pōʻino o nā hui, a me ka hiki ke komo i nā hana maʻamau.

E like me nā lāʻau lapaʻau a pau, hiki ke loaʻa nā hopena ʻaoʻao, akā kakaikahi nā hopena koʻikoʻi. ʻO ka hapa nui o ka poʻe e ʻae maikaʻi i ka lapaʻau a ʻike i ka hoʻomaikaʻi nui ʻana i kā lākou mau hōʻailona a me ke olakino holoʻokoʻa.

He aha ka mea hiki ke kuhi hewa ʻia kēia lapaʻau?

I kekahi manawa, huikau ka poʻe i kēia lapaʻau kikoʻī clotting factor me nā huahana koko ʻē aʻe a i ʻole nā lāʻau lapaʻau. He mea nui e hoʻomaopopo i ka mea āu e loaʻa nei a no ke aha i koho ʻia ai no kou maʻi.

Hiki ke huikau ʻia kēia lapaʻau me:

• Nā hoʻoili koko - e pani ana i ke koko holoʻokoʻa ma mua o nā protein hoʻopaʻa koko kikoʻī
• Nā hoʻoili plasma - i loaʻa nā protein like ʻole, ʻaʻole wale nā mea āu e pono ai
• Nā mea hoʻopaʻa koko ʻē aʻe - i loaʻa nā hui like ʻole o nā protein
• Nā lāʻau lapaʻau hoʻopaʻa koko synthetic - e hana ana i nā ʻano like ʻole ma mua o ka therapy pani
• Nā wai IV maʻamau - ʻaʻole i loaʻa nā mea hoʻopaʻa koko

E hōʻoia kāu hui mālama ola e maopopo pono ana ʻoe i ke ʻano o ka lapaʻau āu e loaʻa nei. Mai kānalua e nīnau i nā nīnau e pili ana i kāu lāʻau lapaʻau a no ke aha ia ka koho maikaʻi loa no kou kūlana kikoʻī.

Nā nīnau i nīnau pinepine ʻia e pili ana i ka lapaʻau Factor VIII a me von Willebrand Factor

Pehea ka lōʻihi o ka lōʻihi o kēlā me kēia kau lapaʻau?

ʻO ka hapa nui o nā infusions ma waena o 30 mau minuke a 2 mau hola, ma muli o kāu mahele a me ke ʻano o kou kino e pane ai. E nānā kāu hui mālama ola iā ʻoe i kēia manawa e hōʻoia e ʻoluʻolu ana ʻoe a e pane maikaʻi ana i ka lapaʻau.

Ehia mau manawa e pono ai iaʻu nā lapaʻau?

He ʻokoʻa nui ka pinepine o ka lapaʻau ma muli o kou kūlana kikoʻī a me ke koʻikoʻi. Pono kekahi poʻe i nā infusions i nā manawa he nui i ka pule no ka pale ʻana, aʻo nā mea ʻē aʻe e pono wale i ka lapaʻau ke loaʻa ke koko a i ʻole ma mua o nā kaʻina hana. E hana kāu kauka i kahi papa manawa kūpono iā ʻoe.

Hiki iaʻu ke hele i ka wā e loaʻa ana kēia lapaʻau?

ʻAe, nui ka poʻe me nā maʻi koko e hele maikaʻi. Pono ʻoe e hoʻolālā i mua ma ka hoʻopili ʻana me nā kikowaena lapaʻau ma kou wahi e hele ai a me ka lawe ʻana i nā lako pilikia. Hiki i kāu hui mālama ola ke kōkua iā ʻoe e hoʻomākaukau no ka hele palekana.

Aia kekahi hopena lōʻihi o kēia lapaʻau?

No ka hapa nui o nā kānaka, he maikaʻi loa nā hopena lōʻihi - ʻoi aku ka maikaʻi o ke olakino, ʻoi aku ka liʻiliʻi o nā hanana koko, a me ka maikaʻi o ke ola. I kekahi manawa, hiki i kekahi poʻe ke hoʻomohala i nā antibodies e hoʻemi ai i ka pono o ka lāʻau, akā e nānā ana kāu mau kauka i kēia a hiki ke hoʻololi i ka lāʻau inā pono.

Ua uhi ʻia kēia lāʻau e ka ʻinikua?

Ua uhi ka hapa nui o nā hoʻolālā ʻinikua i kēia lāʻau no ka mea ua manaʻo ʻia he mea pono no ka poʻe me nā maʻi koko. Eia naʻe, ʻokoʻa nā kikoʻī uhi, no laila he mea nui e hana pū me kāu hui mālama ola a me ka hui ʻinikua e hoʻomaopopo i kāu mau pōmaikaʻi a me nā kumukūʻai hiki.