He aha ʻo Apalutamide: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ʻo Apalutamide e kōkua i ka mālama ʻana i ka maʻi kanesa prostate holomua ma ka pale ʻana i nā hopena o ka testosterone a me nā hormones kāne ʻē aʻe. Hiki i kāu kauka ke ʻōlelo aku i kēia lāʻau lapaʻau ke laha ka maʻi kanesa prostate i nā ʻāpana ʻē aʻe o kou kino a i ʻole ke kiʻekiʻe ka pilikia e laha koke ana.

No ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo androgen receptor inhibitors kēia lāʻau lapaʻau. E noʻonoʻo iā ia e like me ke kau ʻana i kahi pale ikaika e pale ai i nā hormones mai ka hoʻoulu ʻana i ka ulu ʻana o nā cella maʻi kanesa. Nui nā kāne i ʻike e kōkua ana ia i ka hoʻolohi ʻana i ka holomua ʻana o kā lākou maʻi kanesa me ka mālama ʻana i ko lākou maikaʻi o ke ola.

He aha ʻo Apalutamide?

He lāʻau lapaʻau maʻi kanesa waha ʻo Apalutamide e kuhikuhi pono ana i nā cella maʻi kanesa prostate hormone-sensitive. Hana ia ma ka pale ʻana i nā androgen receptors, e like me nā puka e hoʻohana ai nā hormones kāne e komo a hoʻāla i nā cella maʻi kanesa.

Hele mai ka lāʻau lapaʻau ma ke ʻano o nā papa e lawe ʻoe ma ka waha i hoʻokahi manawa i ka lā. Ua hoʻolālā ʻia e lilo i lapaʻau lōʻihi e hana pū ana me nā hana maoli o kou kino e hakakā i ka ulu ʻana o ka maʻi kanesa. E nānā kāu oncologist i ka maikaʻi o kāna hana ʻana ma o nā hoʻokolohua koko maʻamau a me nā haʻawina kiʻi.

ʻAʻole like me kekahi mau lapaʻau maʻi kanesa, ua manaʻo ʻia ʻo apalutamide he lāʻau lapaʻau i manaʻo ʻia ma mua o ka chemotherapy kuʻuna. ʻO ia hoʻi, ua hoʻolālā ʻia e hoʻouka i nā cella maʻi kanesa me ka pololei aʻe me ka hana ʻana i nā hopena ʻaoʻao liʻiliʻi i nā cella olakino.

No ke aha e hoʻohana ʻia ai ʻo Apalutamide?

Hoʻomaʻamaʻa ʻo Apalutamide i nā ʻano nui ʻelua o nā kūlana maʻi kanesa prostate holomua. ʻO ka mea mua, kōkua ia i nā kāne me ka metastatic castration-resistant prostate cancer, ʻo ia hoʻi ua laha ka maʻi kanesa me ka nānā ʻole i nā lapaʻau hormone ʻē aʻe.

ʻO ka lua, kauoha nā kauka iā ia no ka non-metastatic castration-resistant prostate cancer ke kiʻekiʻe ka pilikia e laha ana ka maʻi kanesa. I kēia hihia, hana ia ma ke ʻano he ana pale e hoʻopaneʻe i ka holomua ʻana o ka maʻi kanesa i nā ʻāpana ʻē aʻe o kou kino.

Hiki i kāu kauka ke ʻōlelo aku iā apalutamide me nā lāʻau lapaʻau ʻē aʻe e like me ka lāʻau hormone a i ʻole ka radiation. ʻO ka pahuhopu ka hoʻolohi ʻana i ka ulu ʻana o ka maʻi kanesa, e hōʻemi i nā hōʻailona, a e kōkua iā ʻoe e mālama i ke ola maikaʻi loa.

Pehea e Hana ai ʻo Apalutamide?

Hana ʻo Apalutamide ma ka pale ʻana i ka testosterone a me nā hormones kāne ʻē aʻe mai ka hiki ʻana i nā sela maʻi kanesa prostate. ʻO kēia mau hormones e hana maʻamau e like me ka wahie no nā maʻi kanesa prostate he nui, e kōkua ana iā lākou e ulu a laha i loko o kou kino.

Hoʻopaʻa ka lāʻau lapaʻau i nā mea hoʻokipa androgen ma nā sela maʻi kanesa, e laka ana i ka puka i ʻole e hiki i nā hormones ke komo. Me ka ʻole o kēia wahie hormonal, paʻakikī nā sela maʻi kanesa e hoʻonui a laha e like me ka ikaika e like me ka mea ʻē aʻe.

Ua manaʻo ʻia he lāʻau lapaʻau maʻi kanesa ikaika loa a he mea maikaʻi loa ia no nā maʻi kanesa prostate hormone-sensitive. ʻIke ka hapa nui o nā kāne i nā hoʻomaikaʻi ʻana i kā lākou mau hōʻailona maʻi kanesa i loko o nā mahina mua o ka lāʻau lapaʻau, ʻoiai hiki ke ʻokoʻa nā hopena.

Pehea e Lawe ai au iā Apalutamide?

E lawe iā apalutamide e like me ke kauoha a kāu kauka, maʻamau hoʻokahi manawa i ka lā i ka manawa like i kēlā me kēia lā. Hiki iā ʻoe ke lawe me ka ʻai a i ʻole me ka ʻole o ka ʻai, akā e hoʻāʻo e kūlike me kāu koho e kōkua i kou kino e komo i ka lāʻau.

E ale i nā papa holoʻokoʻa me ke aniani wai piha. Mai ʻoki, nau, a i ʻole e wāwahi iā lākou, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka hoʻokuʻu ʻia ʻana o ka lāʻau lapaʻau i loko o kou kino. Inā pilikia ʻoe i ka ale ʻana i nā pila, e kamaʻilio me kāu kauka e pili ana i nā hoʻolālā e kōkua ai.

He maikaʻi ke lawe iā apalutamide me ka waiū, ka wai, a i ʻole nā mea inu ʻē aʻe inā maʻalahi iā ʻoe. ʻIke kekahi mau kāne i ka lawe ʻana me ka ʻaina kakahiaka e kōkua iā lākou e hoʻomanaʻo i kā lākou lāʻau i kēlā me kēia lā a hōʻemi i nā pilikia o ka ʻōpū.

Pehea ka lōʻihi e lawe ai au iā Apalutamide?

He nui nā kāne e lawe ana i ka apalutamide no nā mahina a i ʻole nā makahiki, ma muli o ka maikaʻi o ka pane ʻana o kā lākou maʻi kanesa i ka lāʻau lapaʻau. E nānā kāu kauka i kou holomua ma o nā hoʻokolohua koko maʻamau a me nā scans e hoʻoholo ai i ka lōʻihi maikaʻi loa no kou kūlana.

E hoʻomau ʻoe i ka lawe ʻana i ka lāʻau lapaʻau i ka wā e kōkua ana ia i ka mālama ʻana i kāu maʻi kanesa me ka ʻole o ka hana ʻana i nā hopena ʻaoʻao hiki ʻole ke ʻae ʻia. Lawe kekahi poʻe i ka lāʻau lapaʻau no kekahi mau makahiki, a ʻo nā mea ʻē aʻe e pono paha e hoʻololi i nā lāʻau lapaʻau ʻē aʻe inā e kūkulu ana kā lākou maʻi kanesa i ke kūpaʻa.

Mai hooki i ka lawe ʻana i ka apalutamide me ka ʻole e kamaʻilio mua me kāu kauka. ʻOiai inā maikaʻi kou manaʻo, e hana ana paha ka lāʻau lapaʻau ma hope o nā hiʻohiʻona e mālama i kāu maʻi kanesa.

He aha nā hopena ʻaoʻao o ka Apalutamide?

E like me nā lāʻau lapaʻau maʻi kanesa a pau, hiki i ka apalutamide ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole nā mea a pau e ʻike iā lākou. ʻO ka lono maikaʻi, hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao me ke kākoʻo kūpono mai kāu hui mālama ola.

Eia nā hopena ʻaoʻao maʻamau e ʻike ai ʻoe i ka wā e lawe ana i ka apalutamide:

• Luhi a me ka manaʻo luhi ma mua o ka maʻamau
• ʻEha hui a me ka ʻiʻo a i ʻole ka ʻoʻoleʻo
• Nā uila wela a me nā hou o ka pō
• Nalo o ka ʻai a me ka pohō kaumaha
• Nā ʻōpala ʻili a i ʻole ka ʻili maloʻo
• Pāpaʻa a i ʻole nā loli i nā neʻe ʻana o ka ʻōpū
• Ke koko kiʻekiʻe

ʻO ka hapa nui o kēia mau hopena ʻaoʻao he maʻalahi a i ka waena a pinepine e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau. Hiki i kāu kauka ke ʻōlelo i nā ala e mālama pono ai iā lākou.

Pono kekahi mau hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi i ka nānā ʻana i ka lāʻau lapaʻau koke. ʻOiai he kakaikahi kēia, he mea nui e ʻike iā lākou:

• Nā hopu a i ʻole nā loli maʻamau i ka hana o ka lolo
• Nā hāʻule nui a i ʻole nā pilikia kaulike
• Nā hōʻailona o nā pilikia o ka naʻau e like me ka ʻeha o ka umauma a i ʻole ka pōkole o ka hanu
• Nā hopena ʻili koʻikoʻi a i ʻole nā ʻōpala ākea
• Nā loli nui i ke ʻano a i ʻole ke kūlana noʻonoʻo

Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona koʻikoʻi, e kelepona koke i kāu kauka a i ʻole e ʻimi i ka lāʻau lapaʻau ulia pōpilikia. E hoʻomanaʻo, aia kāu hui mālama ola e kōkua iā ʻoe e hoʻokele i nā pilikia e kū mai ana.

ʻO wai ka mea pono ʻole e lawe iā Apalutamide?

ʻAʻole kūpono ʻo Apalutamide no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana. ʻAʻole pono nā wahine e hāpai ana a i ʻole e hāpai ana e lawe i kēia lāʻau, no ka mea, hiki iā ia ke hōʻeha nui i nā pēpē e ulu ana.

Pono ka poʻe me kekahi mau maʻi olakino i ka noʻonoʻo kūikawā ma mua o ka hoʻomaka ʻana iā apalutamide. E loiloi kāu kauka i kou olakino holoʻokoʻa e hōʻoia i ka palekana iā ʻoe:

• Mōʻaukala o nā hopu a i ʻole nā maʻi lolo
• Nā pilikia o ka naʻau nui a i ʻole nā puʻuwai puʻuwai hou
• Maʻi ate a i ʻole nā enzyme ate i hoʻokiʻekiʻe nui ʻia
• Nā pilikia kīkī nui
• Mōʻaukala o ka hāʻule a i ʻole nā pilikia kaulike nui

Eia kekahi, hiki i kekahi mau lāʻau lapaʻau ke launa pū me apalutamide, e hoʻemi ana i ka maikaʻi a i ʻole ka hoʻonui ʻana i nā hopena ʻaoʻao. E haʻi mau i kāu kauka e pili ana i nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā huahana lāʻau lapaʻau āu e lawe nei.

Nā inoa inoa Apalutamide

ʻIke nui ʻia ʻo Apalutamide e kona inoa inoa ʻo Erleada. ʻO kēia ka mana āu e loaʻa ai mai kāu hale kūʻai lāʻau lapaʻau, i hana ʻia e Janssen Pharmaceuticals.

I kēia manawa, ʻo Erleada ka inoa nui i loaʻa ma ka hapa nui o nā ʻāina, ʻoiai e loaʻa paha nā mana generic i ka wā e hiki mai ana. Hiki i kāu ʻinikua a me ka hale kūʻai lāʻau lapaʻau ke hoʻopilikia i ka mana kikoʻī āu e loaʻa ai.

Nā koho ʻē aʻe o Apalutamide

He nui nā lāʻau lapaʻau ʻē aʻe e hana like me apalutamide no ka mālama ʻana i ka maʻi maʻi prostate holomua. Hiki i kāu kauka ke noʻonoʻo i kēia mau koho ʻē aʻe inā ʻaʻole kūpono ʻo apalutamide iā ʻoe a i ʻole e pau ka hana ʻana.

ʻO nā koho nui e komo pū ana me ka enzalutamide (Xtandi), darolutamide (Nubeqa), a me ka bicalutamide (Casodex). He ʻokoʻa iki nā pōmaikaʻi a me nā hopena ʻaoʻao o kēlā me kēia, no laila e kōkua kāu kauka iā ʻoe e koho i ke koho maikaʻi loa no kou kūlana.

Hiki i nā ala lapaʻau ʻē aʻe ke komo i ka chemotherapy, immunotherapy, a i ʻole nā ​​lapaʻau i manaʻo ʻia. ʻO ke koho maikaʻi loa e hilinaʻi ana i nā ʻano o kāu maʻi maʻi, kou olakino holoʻokoʻa, a me kāu mau makemake pilikino.

Ua ʻoi aku ka maikaʻi o Apalutamide ma mua o Enzalutamide?

He mau lāʻau lapaʻau maikaʻi loa ʻo Apalutamide a me enzalutamide no ka maʻi maʻi prostate holomua, a ʻaʻole i

Inā ua lawe ʻoe i ka nui aʻe o kāu lāʻau i kuhikuhi ʻia, e kelepona koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau make. ʻO ka lawe ʻana i ka nui o ka apalutamide hiki ke hoʻonui i kou pilikia o nā hopena ʻaoʻao koʻikoʻi, ʻo ia hoʻi nā ʻāʻā.

Mai kali e ʻike inā maikaʻi ʻoe. ʻOiai inā ʻaʻole ʻoe e ʻike i nā hōʻailona, ​​he mea nui e kiʻi i ka ʻōlelo aʻoaʻo lapaʻau i kēia manawa. Hiki i kāu kauka ke nānā iā ʻoe a hāʻawi i ka mālama kūpono inā pono.

He aha kaʻu e hana ai inā ua hala wau i kahi mahele o Apalutamide?

Inā ua hala ʻoe i kahi mahele a ua hala ma lalo o 12 mau hola mai kou manawa maʻamau, e lawe koke iā ia ke hoʻomanaʻo ʻoe. Inā ua hala ma mua o 12 mau hola, e lele i ka mahele i hala a lawe i kāu mahele aʻe i ka manawa maʻamau.

Mai lawe i ʻelua mahele i ka manawa like e hoʻoponopono ai i kahi mahele i hala. Hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao me ka hāʻawi ʻole ʻana i ka pōmaikaʻi hou. Inā poina pinepine ʻoe i nā mahele, e noʻonoʻo e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Apalutamide?

Pono ʻoe e hooki i ka lawe ʻana i ka apalutamide ke haʻi aku kāu kauka iā ʻoe he kūpono. Hana maʻamau kēia inā ʻaʻole e hoʻomalu hou ka lāʻau i kāu maʻi maʻi, inā ʻoe e ʻike nei i nā hopena ʻaoʻao hiki ʻole ke ʻae ʻia, a i ʻole inā ua pane maikaʻi kāu maʻi maʻi i hiki ke hoʻomaha i ka lāʻau.

Lawe kekahi mau kāne i ka apalutamide no nā makahiki, ʻoiai pono paha nā mea ʻē aʻe e hoʻololi i nā lāʻau lapaʻau i ka wā mua. E hoʻohana kāu kauka i nā hoʻokolohua koko, nā scans, a me ke ʻano o kou manaʻo e hoʻoholo ai i ka manawa maikaʻi loa e hooki ai a hoʻololi paha i kāu lāʻau lapaʻau.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Apalutamide?

He maikaʻi ka ʻai ʻana i ka waiʻona i ka wā e lawe ana i ka apalutamide, akā ʻoi aku ka maikaʻi e kūkākūkā i kēia me kāu kauka. Hiki i ka waiʻona ke hoʻonui i kekahi mau hopena ʻaoʻao e like me ka dizziness a i ʻole ka luhi, a hiki ke hoʻopilikia i ka hana ʻana o kou kino i ka lāʻau.

Inā koho ʻoe e inu i ka waiʻona, e hana pēlā me ke ana a e hoʻolohe i kou manaʻo. ʻIke kekahi mau kāne i ka hopena ʻokoʻa o ka waiʻona iā lākou i ka wā e mālama ʻia ai ka maʻi kanesa, no laila he mea nui e hoʻolohe i kou kino a hoʻoponopono e like me ia.