He aha ʻo Atazanavir a me Cobicistat: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Atazanavir a me cobicistat he lāʻau hui pū e mālama ai i ka maʻi HIV i nā pākeke a me nā keiki. Hana pū kēia hui ikaika e kōkua i ka mālama ʻana i ka maʻi a pale i kou ʻōnaehana pale mai ka pōʻino hou aku.

Ke noho nei ʻoe me ka HIV, hiki i nā koho lapaʻau kūpono ke lawe mai i ka maluhia nui o ka noʻonoʻo. Hōʻike kēia hui lāʻau i kahi mea hana nui i ka mālama HIV hou, i hoʻolālā ʻia e hana i kāu lapaʻau i maʻalahi a ʻoi aku ka maikaʻi.

He aha ʻo Atazanavir a me Cobicistat?

Hoʻohui ʻo Atazanavir a me cobicistat i ʻelua ʻano lāʻau HIV like ʻole i hoʻokahi pila maʻalahi. No ka papa o nā lāʻau i kapa ʻia he protease inhibitors ʻo Atazanavir, ʻoiai ʻo cobicistat e hana ma ke ʻano he mea hoʻoikaika e kōkua ai iā atazanavir e hana ʻoi aku ka maikaʻi i kou kino.

E noʻonoʻo iā cobicistat ma ke ʻano he mea kōkua e hōʻoia ana e noho ikaika ʻo atazanavir i loko o kāu ʻōnaehana no ka lōʻihi. Me ka ʻole o cobicistat, e wāwahi kou kino iā atazanavir i ka wikiwiki, e hoʻemi ana i ka maikaʻi i ka hakakā ʻana i ka HIV.

Hoʻohana mau ʻia kēia hui pū me nā lāʻau HIV ʻē aʻe ma ke ʻano he ʻāpana o ka mea a nā kauka e kapa ai he highly active antiretroviral therapy (HAART). ʻAʻole ʻoe e lawe i kēia lāʻau wale nō no ka mea e hana maikaʻi ana ka lapaʻau HIV ke hoʻouka nā lāʻau he nui i ka maʻi mai nā kihi like ʻole.

No ke aha e hoʻohana ʻia ai ʻo Atazanavir a me Cobicistat?

Mālama kēia hui lāʻau i ka maʻi HIV-1, ke ʻano maʻamau o ka HIV ma ka honua holoʻokoʻa. Ua hoʻolālā ʻia no ka poʻe e hoʻomaka ana i ka lapaʻau HIV no ka manawa mua a i ʻole e hoʻololi ana mai nā lāʻau HIV ʻē aʻe.

Hiki i kāu kauka ke kuhikuhi i kēia hui inā pono ʻoe i kahi papa lapaʻau ikaika a maʻalahi. Nui ka poʻe e mahalo i ka loaʻa ʻana o nā pila liʻiliʻi e lawe i kēlā me kēia lā, hiki ke maʻalahi ka pili ʻana i kāu papa hana lapaʻau.

He hana maikaʻi ka lāʻau lapaʻau no ka poʻe i loaʻa ʻole ka maʻi HIV i ka pale ʻana i nā mea pale protease. E hana paha kāu mea mālama ola i nā hoʻokolohua e hōʻoia i ka kūpono o kēia hui ʻana no kou kūlana.

Pehea e hana ai ʻo Atazanavir a me Cobicistat?

Hoʻopaʻa ʻo Atazanavir i kahi enzyme i kapa ʻia ʻo HIV protease, pono ka maʻi e hana i nā kope hou o ia iho. Ke ālai ʻia kēia enzyme, ʻaʻole hiki i ka HIV ke hana hou, a emi nui ka ukana viral i loko o kou koko.

ʻAʻole hakakā pololei ʻo Cobicistat i ka HIV, akā pale ia i kou ate mai ka wāwahi ʻana iā atazanavir i ka wikiwiki. ʻO kēia hopena booster ke hiki iā atazanavir ke noho ikaika i loko o kāu ʻōnaehana no 24 mau hola me hoʻokahi wale nō lā.

Manaʻo ʻia kēia he hui lāʻau lapaʻau HIV ikaika. He ikaika ia e kāohi pono i ka maʻi i ka hapanui o nā kānaka, akā ua ʻae maikaʻi ʻia ma mua o kekahi mau lāʻau lapaʻau HIV kahiko.

Hana maikaʻi ka hui ʻana ke lawe mau ʻia i kēlā me kēia lā i ka manawa like. ʻO ka nalo ʻana i nā lāʻau lapaʻau hiki ke ʻae i ka HIV e hoʻonui hou a hiki ke hoʻomohala i ka pale ʻana i ka lāʻau lapaʻau.

Pehea wau e lawe ai iā Atazanavir a me Cobicistat?

E lawe i kēia lāʻau lapaʻau i hoʻokahi manawa i ka lā me ka meaʻai, ʻoi aku ka maikaʻi i ka manawa like i kēlā me kēia lā. Kōkua ka meaʻai i kou kino e komo pono i ka lāʻau lapaʻau a hiki ke hōʻemi i ka manawa o ka ʻōpū.

Hiki iā ʻoe ke lawe me kekahi meaʻai a i ʻole meaʻai nui, akā e pale i ka lawe ʻana ma ka ʻōpū ʻole. He hana maikaʻi ka meaʻai māmā me kekahi protein a i ʻole ka momona, e like me ka toast me ka pata pīkī a i ʻole ka yogurt me ka granola.

E ale i ka papa holoʻokoʻa me ka wai a i ʻole kekahi mea inu. Mai ʻoki, nau, a i ʻole e māhele i ka papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka lawe ʻana a me ka hoʻokuʻu ʻia ʻana o ka lāʻau lapaʻau i loko o kou kino.

Inā ʻoe e lawe i nā antacids, e hoʻokaʻawale iā lākou mai kēia lāʻau lapaʻau ma ka liʻiliʻi he 2 mau hola ma mua a i ʻole 1 hola ma hope o ka lawe ʻana iā atazanavir a me cobicistat. Hiki i nā antacids ke keakea i ka maikaʻi o kou kino e komo i ka lāʻau lapaʻau.

Pehea ka lōʻihi e lawe ai au i ka Atazanavir a me Cobicistat?

Pono ʻoe e lawe i kēia lāʻau no ka lōʻihi e ʻōlelo ai kāu kauka, ʻo ia hoʻi no ke ola. He hana lōʻihi ka mālama ʻana i ka HIV, a ʻo ka hooki ʻana i ka lāʻau lapaʻau hiki ke ʻae i ka maʻi e hoʻonui wikiwiki hou.

Ke hoʻomau nei ka hapa nui o nā kānaka i ka lawe ʻana i kā lākou lāʻau HIV no ka manawa pau ʻole e mālama i kahi ukana viral hiki ʻole ke ʻike ʻia. Ke hiki ʻole ke ʻike ʻia ka HIV, ʻaʻole hiki ke hoʻoili ʻia i nā poʻe ʻē aʻe, a noho olakino kou ʻōnaehana pale.

E nānā kāu kauka i kāu pane ʻana i ka lāʻau lapaʻau ma o nā hoʻokolohua koko maʻamau, maʻamau i kēlā me kēia 3 a 6 mahina. Hoʻāʻo kēia mau hoʻokolohua i kāu ukana viral a me ka helu CD4 e hōʻoia i ka hana pono ʻana o ka lāʻau.

Mai hooki i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole e kamaʻilio mua me kāu mea mālama ola. ʻOiai inā maikaʻi loa ʻoe, aia nō ka maʻi i loko o kou kino a pono i ka lāʻau lapaʻau e hoʻomau ʻia e noho i ka mana.

He aha nā hopena ʻaoʻao o Atazanavir a me Cobicistat?

E like me nā lāʻau lapaʻau a pau, hiki i ka atazanavir a me ka cobicistat ke hana i nā hopena ʻaoʻao, ʻoiai he nui ka poʻe e ʻae maikaʻi iā ia. ʻO ka hapa nui o nā hopena ʻaoʻao he maʻalahi a maʻa mau e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau i nā pule mua.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike:

• Nausea a me ka ʻoluʻolu ʻole o ka ʻōpū
• Poʻo
• Luhi a i ʻole ka luhi ma mua o ka maʻamau
• Pāpaʻa a i ʻole nā ʻōpū palupalu
• Melemele o ka ʻili a i ʻole nā maka (jaundice)
• ʻO ka ʻōpala a i ʻole ka huhū o ka ʻili
• ʻĀina

Hana ʻia ka melemele o ka ʻili a i ʻole nā maka no ka mea hiki i ka atazanavir ke hoʻonui i nā pae bilirubin i loko o kou koko. He mea ʻole kēia a hiki ke hoʻohuli ʻia, akā he mea nui e haʻi aku i kāu kauka.

ʻIke kekahi poʻe i nā hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau e koi i ka lāʻau lapaʻau:

• Ka luaʻi nui a i ʻole ka luaʻi ʻana
• ʻehaʻeha a nāwaliwali paha o nā ʻiʻo
• Paʻakikī ka hanu ʻana
• ʻehaʻeha nui o ka ʻōpū
• Nā hōʻailona o nā pilikia o ke ake (mimi ʻeleʻele, luhi nui, nalowale o ka ʻai)
• Ka puʻuwai ʻole
• ʻŌpala nui me ke kuni

ʻO nā hopena ʻaoʻao laha ʻole akā koʻikoʻi e komo pū ana me nā pilikia o ka puʻupaʻa, nā loli i ka puʻuwai, a me nā hopena maʻi maʻi nui. E nānā mau kāu kauka iā ʻoe e hopu i nā pilikia hiki ke hiki i ka wā mua.

E hoʻokaʻaʻike i kāu mea mālama ola inā ʻike ʻoe i nā hōʻailona e pili ana, ʻoiai inā e hoʻomau a ʻino paha i ka manawa. Hiki ke mālama pono ʻia ka hapa nui o nā hopena ʻaoʻao me ke alakaʻi olakino kūpono.

ʻO wai ka mea pono ʻole e lawe iā Atazanavir a me Cobicistat?

ʻAʻole kūpono kēia lāʻau lapaʻau no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ka kau ʻana. Hiki i kekahi mau maʻi a me nā lāʻau lapaʻau ke palekana ʻole a i ʻole ka liʻiliʻi o kēia hui.

ʻAʻole pono ʻoe e lawe i kēia lāʻau lapaʻau inā loaʻa iā ʻoe:

• Maʻi ate nui a i ʻole cirrhosis
• Nā pilikia o ka puʻuwai
• Maʻi puʻupaʻa nui
• ʻIke ʻia ka maʻi maʻi iā atazanavir, cobicistat, a i ʻole kekahi mea i loko o ka lāʻau lapaʻau

Hiki i kekahi mau lāʻau lapaʻau ke launa pū me atazanavir a me cobicistat, no laila pono kāu kauka e ʻike e pili ana i nā mea a pau āu e lawe ai, me:

• Nā lāʻau lapaʻau no ka hopu ʻana
• Nā lāʻau antibiotic a me nā lāʻau antifungal
• Nā lāʻau lapaʻau puʻuwai
• Nā mea pale pamu proton no ka reflux acid
• Nā lāʻau hoʻohaʻahaʻa cholesterol
• Nā lāʻau lapaʻau psychiatric

Pono ka poʻe me ka maʻi diabetes e hoʻohana i kēia lāʻau lapaʻau me ka akahele, no ka mea, hiki iā ia ke hoʻopilikia i nā pae kōpaʻa koko. Pono paha kāu kauka e hoʻoponopono i kāu mau lāʻau lapaʻau diabetes a i ʻole e nānā pono i kāu kōpaʻa koko.

Hiki i nā wāhine hāpai ke lawe i kēia lāʻau lapaʻau, akā pono ia i ka nānā kūikawā. Hiki i ka lāʻau lapaʻau ke hele i loko o ka waiū umauma, no laila e kūkākūkā i nā koho hānai me kāu mea mālama ola.

Nā inoa inoa o Atazanavir a me Cobicistat

ʻO ka inoa inoa no ka hui pū ʻana o atazanavir a me cobicistat ʻo Evotaz. ʻO kēia ke ʻano i kauoha pinepine ʻia o kēia hui lāʻau lapaʻau ma ʻAmelika Hui Pū ʻIa.

Hiki nō hoʻi iā ʻoe ke hālāwai me nā mea i kūʻai ʻia i ka ʻokoʻa. Hoʻokahi wale nō ʻo Atazanavir i kūʻai ʻia ma lalo o ka inoa inoa ʻo Reyataz, aʻo cobicistat i loaʻa ma ke ʻano he Tybost.

Hiki ke loaʻa nā mana generic o ka hui ʻana i ka manawa, akā i kēia manawa, ʻo Evotaz ke koho mua. E hāʻawi maʻamau kāu hale kūʻai lāʻau lapaʻau i ka inoa inoa ke ʻole ʻoe a me kāu kauka e noi kūikawā.

Nā koho ʻē aʻe o Atazanavir a me Cobicistat

Nui nā hui lāʻau lapaʻau HIV ʻē aʻe e hiki ke lilo i nā koho ʻē aʻe inā ʻaʻole hana maikaʻi ʻo atazanavir a me cobicistat iā ʻoe. Hiki i kāu kauka ke ʻōlelo e hoʻololi inā loaʻa iā ʻoe nā hopena ʻaoʻao a i ʻole inā ʻaʻole pane kūpono kāu ukana viral.

ʻO nā hui inhibitor protease ʻē aʻe e komo pū ana:

\n
• Darunavir me cobicistat a i ʻole ritonavir
\n
• Lopinavir me ritonavir
\n
• Tipranavir me ritonavir
\n

ʻO nā koho ʻē aʻe ʻaʻole protease inhibitor e komo pū ana i nā mea hoʻohui integrase e like me dolutegravir a i ʻole bictegravir, i hui pinepine ʻia me nā papa ʻē aʻe o nā lāʻau lapaʻau HIV. He mau koho paha kēia inā pono ʻoe e pale loa i nā mea hoʻohui protease.

E noʻonoʻo kāu mea mālama ola i kāu mōʻaukala olakino kikoʻī, nā lāʻau lapaʻau ʻē aʻe, a me nā ʻano kūʻē lāʻau i ke koho ʻana i ke koho maikaʻi loa iā ʻoe.

ʻOi aku ka maikaʻi o Atazanavir a me Cobicistat ma mua o Darunavir?

He mau lāʻau lapaʻau HIV maikaʻi ʻo Atazanavir a me cobicistat a me darunavir (i hui pū ʻia me cobicistat a i ʻole ritonavir), akā he mau pono like ko lākou. ʻO ke koho

Hiki ke makemake ʻia ʻo Atazanavir a me cobicistat inā makemake ʻoe i ka lāʻau hoʻokahi i ka lā me ka liʻiliʻi o nā pilina lāʻau. He liʻiliʻi nō hoʻi ka hopena i nā pae cholesterol i hoʻohālikelike ʻia me kekahi mau mea pale protease.

Hiki ke koho ʻia nā hui Darunavir inā loaʻa iā ʻoe ka maʻi HIV i kūʻē i nā mea pale protease ʻē aʻe, no ka mea, he pale kiʻekiʻe ʻo darunavir i ke kūʻē. Makemake pinepine ʻia no ka poʻe i lawe i nā lāʻau HIV ma mua.

E noʻonoʻo kāu kauka i nā mea e like me kāu mōʻaukala lapaʻau, nā pilina lāʻau hiki ke loaʻa, nā ʻaoʻao hopena, a me nā makemake pilikino i ke kōkua ʻana iā ʻoe e koho ma waena o kēia mau koho.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Atazanavir a me Cobicistat

He palekana anei ʻo Atazanavir a me Cobicistat no ka poʻe me ka maʻi diabetes?

ʻAe, hiki i ka poʻe me ka maʻi diabetes ke lawe i ka atazanavir a me cobicistat, akā pono ia i ka nānā pono ʻana. Hiki i kēia lāʻau lapaʻau ke hoʻopilikia i nā pae kōpaʻa koko, e hiki ai ke kiʻekiʻe ma mua o ka maʻamau.

Makemake paha kāu kauka e nānā pinepine i kāu kōpaʻa koko ke hoʻomaka ʻoe i kēia lāʻau lapaʻau. Pono paha ʻoe e hoʻoponopono i kāu mau lāʻau lapaʻau diabetes a i ʻole nā ​​doses insulin e mālama pono i kāu kōpaʻa koko.

ʻO ka lono maikaʻi, hiki i ka hapa nui o ka poʻe me ka maʻi diabetes ke lawe pono i kēia lāʻau HIV me ka mālama olakino kūpono. Mai ʻae i nā hopohopo diabetes e pale iā ʻoe mai ka loaʻa ʻana o ka lāʻau HIV maikaʻi.

He aha kaʻu e hana ai inā lawe hewa au i ka nui o Atazanavir a me Cobicistat?

Inā lawe hewa ʻoe i ka nui ma mua o kāu mahele i kuhikuhi ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena mana ʻawa. ʻO ka lawe ʻana i ka nui o kēia lāʻau lapaʻau hiki ke pilikia a hiki ke hoʻoulu i nā hopena ʻaoʻao koʻikoʻi.

ʻO nā hōʻailona o ka overdose e komo paha i ka nausea koʻikoʻi, ka luaʻi, ka dizziness, a i ʻole nā ​​pilikia o ka puʻuwai. Mai kali e ʻike inā e ulu nā hōʻailona, ​​e ʻimi koke i ka lāʻau lapaʻau.

I mea e pale ai i ka nui o nā lāʻau i lawe ʻia me ka manaʻo ʻole, e hoʻohana i ka mea hoʻonohonoho lāʻau a lawe i kāu lāʻau i ka manawa like i kēlā me kēia lā. Inā ʻaʻole ʻoe i maopopo inā ua lawe ʻoe i kāu lāʻau, ʻoi aku ka palekana o ka lele ʻana ma mua o ka pilikia o ka lawe ʻana i ka pālua.

He aha kaʻu e hana ai inā ua hala wau i kahi lāʻau o Atazanavir a me Cobicistat?

Inā ua hala ʻoe i kahi lāʻau a ua hala ma lalo o 12 mau hola mai kou manawa maʻamau, e lawe i ka lāʻau i hala me ka meaʻai i ka wā e hoʻomanaʻo ai ʻoe. Inā ua hala ma mua o 12 mau hola, e lele i ka lāʻau i hala a lawe i kāu lāʻau aʻe i ka manawa maʻamau.

Mai lawe i ʻelua lāʻau i ka manawa hoʻokahi e hoʻopiha ai i kahi lāʻau i hala. Hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao me ka ʻole o ka hāʻawi ʻana i ka pōmaikaʻi hou.

E hoʻāʻo e hōʻemi i nā lāʻau i hala ma ka hoʻonohonoho ʻana i nā ʻōhua kelepona, ka hoʻohana ʻana i nā mea hoʻonohonoho lāʻau, a i ʻole ka hoʻopili ʻana i kou manawa lāʻau i kahi hana maʻamau i kēlā me kēia lā e like me ka ʻaina kakahiaka a i ʻole ka ʻaina awakea.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Atazanavir a me Cobicistat?

Pono ʻoe e hoʻomau i ka lawe ʻana iā atazanavir a me cobicistat no ka lōʻihi o ka ʻōlelo a kāu kauka, ʻo ia ka mea maʻamau no ke ola. He maʻi maʻi ʻo HIV e pono ai ka mālama mau ʻana e noho i ka mana.

Hiki i kāu kauka ke noʻonoʻo e hoʻololi i kāu lāʻau lapaʻau inā ʻoe e ʻike i nā hopena ʻaoʻao hiki ʻole ke ʻae ʻia a i ʻole inā e kūkulu ʻia ka pale ʻana o kāu HIV i ka lāʻau lapaʻau o kēia manawa. Eia naʻe, e hoʻololi ʻoe i kahi lāʻau HIV ʻē aʻe ma mua o ka hooki ʻana i ka lāʻau lapaʻau.

ʻOiai inā lilo kāu ukana viral i mea hiki ʻole ke ʻike ʻia, pono ʻoe e hoʻomau i ka lawe ʻana i nā lāʻau HIV e mālama i kēlā kūlana. ʻO ka hooki ʻana i ka lāʻau lapaʻau e hiki ai i ka maʻi ke hoʻonui wikiwiki a hiki ke alakaʻi i ka holomua o ka AIDS.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Atazanavir a me Cobicistat?

Hiki iā ʻoe ke inu i ka waiʻona me ka maʻalahi i ka wā e lawe ana iā atazanavir a me cobicistat, akā he mea nui e makaʻala. Hiki i ka waiʻona ke hoʻonui i ka pilikia o nā pilikia o ke ake, a no ka mea hiki i kēia lāʻau ke hoʻopilikia i ka hana o ke ake, pono ka noʻonoʻo pono ʻana i ka hui ʻana.

Inā koho ʻoe e inu, e pili i nā mea liʻiliʻi a pale i ka inu nui. E kamaʻilio me kāu kauka e pili ana i ka mea e hana ai i ka inu ʻona palekana no kāu kūlana kikoʻī.

E hoʻomanaʻo hiki i ka waiʻona ke keakeʻe i kou hiki ke lawe i nā lāʻau lapaʻau me ke kūpaʻa a hiki ke hoʻonui i kekahi mau hopena ʻaoʻao e like me ka nausea a i ʻole ka ʻūlū.