He aha ʻo Azacitidine: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau maʻi ʻo Azacitidine e kōkua ana i ka mālama ʻana i kekahi mau maʻi koko ma ka hana ʻana ma ka pae genetic e hoʻihoʻi i ka hana maʻamau o ke keena. ʻO ia ka mea a nā kauka e kapa ai he "hypomethylating agent," ʻo ia hoʻi, kōkua ia i ka hoʻihoʻi ʻana i nā genes i hoʻopaʻa ʻia e nā keena maʻi, e ʻae ana i kou kino e hakakā i ka maʻi me ka ʻoi aku ka maikaʻi.

Ua lawe mai kēia lāʻau lapaʻau i ka manaʻolana i nā maʻi he nui me nā maʻi koko i loaʻa nā koho lapaʻau liʻiliʻi ma mua. ʻOiai e koi ana i ka nānā pono ʻana a hele mai me nā hopena ʻaoʻao, ua kōkua ʻo azacitidine i ka hoʻolōʻihi a hoʻomaikaʻi i ka maikaʻi o ke ola no nā tausani o nā kānaka ma ka honua holoʻokoʻa.

He aha ʻo Azacitidine?

ʻO Azacitidine kahi mana synthetic o kahi poloka kūlohelohe o DNA i kapa ʻia ʻo cytidine. Hana ia ma ka hoʻokomo ʻia ʻana i loko o kou DNA a me RNA, a laila e ālai ana i kahi enzyme i kapa ʻia ʻo DNA methyltransferase e hoʻohana ai nā keena maʻi e hoʻopaʻa i nā genes koʻikoʻi.

E noʻonoʻo iā ia he kī molekala e wehe i nā genes e pono ai kou kino e hakakā i ka maʻi. Ke hoʻonui nei nā keena maʻi, pinepine lākou e "hoʻopau" i nā genes e hoʻōki maʻamau i ko lākou ulu ʻana a i ʻole e hoʻoulu i ka make ʻana o ke keena. Kōkua ʻo Azacitidine i ka hoʻihoʻi ʻana i kēia mau genes pale, e hāʻawi ana i kāu ʻōnaehana pale i kahi manawa maikaʻi e ʻike a hoʻouka i nā keena maʻi.

No kahi papa i kapa ʻia ʻo antimetabolites kēia lāʻau lapaʻau, ʻo ia hoʻi, ke keakea nei i ka metabolism cell maʻi a me ka hana DNA. ʻAʻole like me nā lāʻau chemotherapy e ʻona pololei i nā keena maʻi, hana ʻo azacitidine me ka maʻalahi ma ka hoʻololi ʻana i ke ʻano o ka hana ʻana o nā keena maʻi.

No ke aha e hoʻohana ʻia ai ʻo Azacitidine?

Hoʻohana nui ʻia ʻo Azacitidine e mālama i nā maʻi myelodysplastic (MDS), kahi hui o nā maʻi koko kahi e hana ʻole ai kou iwi i nā keena koko olakino. Ua ʻae ʻia nō hoʻi no kekahi mau ʻano o ka acute myeloid leukemia (AML) i nā maʻi ʻaʻole kūpono i ka chemotherapy ikaika.

Hiki i kāu kauka ke ʻōlelo aku iā azacitidine inā loaʻa iā ʻoe nā ʻano MDS e pili ana i ka anemia refractory, refractory anemia me nā sideroblasts i hoʻopaʻa ʻia, a i ʻole refractory anemia me nā blasts nui. Hoʻokumu kēia mau kūlana i ka hana ʻana o kou iwi i nā keena koko ʻano ʻē ʻaʻole hana pono, e alakaʻi ana i ka anemia, ka piʻi ʻana o ka pilikia o ka maʻi, a me nā pilikia koko.

Hoʻohana ʻia ka lāʻau lapaʻau i kekahi manawa no ka leukemia myelomonocytic maʻi (CMML), kekahi maʻi koko e pili ana i nā keʻena koko keʻokeʻo. I kekahi mau hihia, hiki i nā kauka ke noʻonoʻo iā ia no nā maʻi koko ʻē aʻe i ka wā ʻaʻole kūpono nā lāʻau lapaʻau maʻamau a i ʻole ʻaʻole i hana.

ʻAʻole maʻamau, hiki ke hoʻohana ʻia ʻo azacitidine ma waho o ka lepili no kekahi mau ʻōpū paʻa i ka wā i hāʻule ai nā lāʻau lapaʻau ʻē aʻe, ʻoiai e koi ana kēia i ka noʻonoʻo pono e kāu hui oncology.

Pehea e hana ai ʻo Azacitidine?

Hana ʻo Azacitidine ma ka hoʻopilikia ʻana i ka methylation DNA, kahi hana e hoʻohana ai nā keena maʻi e hāmau i nā genes e pale maʻamau i ka ulu ʻana o ka maʻi. Ke loaʻa iā ʻoe ka injection, hele ka lāʻau lapaʻau ma kou kahe koko a hoʻokomo ʻia i loko o ka DNA o nā keena e māhele wikiwiki ana, me nā keena maʻi.

I loko o ka DNA, pahele ʻo azacitidine a hoʻopau i ka enzyme DNA methyltransferase, kahi e hilinaʻi ai nā keena maʻi e mālama i nā genes suppressor tumor i pio. Hāʻawi kēia i nā genes nui e like me p16 a me p15 e hana hou, e kōkua ana i ka hoʻihoʻi ʻana i ka mana o ke keena maʻamau a me ka hoʻomaka ʻana i ka make ʻana o ke keena maʻi.

Hoʻopilikia pū ka lāʻau lapaʻau i ka RNA, e hoʻopilikia ana i ka hana protein i nā keena maʻi. ʻO kēia hana pālua ma ka DNA a me ka RNA e hana ai ʻo azacitidine i mea kūpono loa i nā maʻi koko i lilo i mea pale i nā lāʻau lapaʻau ʻē aʻe.

Ua manaʻo ʻia ʻo Azacitidine he lāʻau lapaʻau maʻi ikaika. ʻAʻole ikaika e like me nā regimens chemotherapy kiʻekiʻe, akā ʻoi aku ka ikaika ma mua o nā lāʻau lapaʻau hormone a i ʻole nā lāʻau lapaʻau i manaʻo ʻia. ʻO ka hapa nui o nā maʻi e ʻae maikaʻi iā ia ma mua o ka chemotherapy kuʻuna a ʻike nō naʻe i nā hopena koʻikoʻi.

Pehea e lawe ai au i ka Azacitidine?

Hāʻawi ʻia ka Azacitidine ma ke ʻano he injection ma lalo o kou ʻili (subcutaneous) a i ʻole i loko o ke aʻa (intravenous), maʻamau i loko o ke keʻena o ke kauka a i ʻole ke kikowaena maʻi maʻi outpatient. ʻAʻole hiki iā ʻoe ke lawe i kēia lāʻau lapaʻau ma ka waha, no ka mea, pono e lawelawe ʻia e nā poʻe loea mālama ola.

ʻO ka papa manawa maʻamau e pili ana i ka loaʻa ʻana o nā injections no nā lā ʻehiku i ka lālani, a ma hope e hoʻomaha ana ma kahi o ʻekolu pule. A laila hana hou kēia pōʻai 28-lā, akā hiki i kāu kauka ke hoʻoponopono i ka manawa ma muli o ke ʻano o ka pane ʻana o kou kino a me kāu helu koko.

Ma mua o kēlā me kēia injection, e nānā kāu hui mālama ola i kāu helu koko a me ke kūlana olakino holoʻokoʻa. ʻAʻole pono ʻoe e hoʻokē ʻai ma mua o ka mālama ʻana, akā ʻo ka ʻai ʻana i ka meaʻai māmā ma mua hiki ke kōkua i ka pale ʻana i ka nausea. ʻO ka inu ʻana i ka wai nui i nā lā lapaʻau e kōkua i kou mau puʻupaʻa e hana i ka lāʻau lapaʻau.

E hoʻololi ʻia kāu mau wahi injection e pale ai i ka huhū, maʻamau e hoʻololi ana ma waena o kou mau ʻūhā, ʻōpū, a me nā lima luna. He mau minuke wale nō ka injection ponoʻī, akā pono paha ʻoe e noho no ka nānā ʻana, ʻoi aku hoʻi i kāu mau lāʻau mua.

Pehea ka lōʻihi e lawe ai au i ka Azacitidine?

Hoʻomau ka hapa nui o nā maʻi i ka azacitidine no ka liʻiliʻi o ʻehā a ʻeono pōʻai (ma kahi o 4-6 mahina) ma mua o ka hiki i nā kauka ke loiloi piha inā e hana ana. Nui ka poʻe e pane maikaʻi i ka lāʻau lapaʻau e hoʻomau i ka mālama ʻana no ka lōʻihi, i kekahi manawa no nā makahiki, inā lākou e ʻae maikaʻi ana a ke kāohi nei i kā lākou maʻi maʻi.

E nānā kāu kauka i kāu helu koko a me ke olakino holoʻokoʻa i kēlā me kēia pule e hoʻoholo ai inā e kōkua ana ka lāʻau lapaʻau. ʻIke kekahi poʻe maʻi i ka maikaʻi i loko o nā pōʻai mua, aʻo nā mea ʻē aʻe e pono e lōʻihi e hōʻike i nā pōmaikaʻi. ʻO ka pahuhopu ka loaʻa ʻana o ke kaulike kūpono ma waena o ka mālama ʻana i kāu maʻi maʻi a me ka mālama ʻana i kou ola maikaʻi.

Inā loaʻa iā ʻoe nā hopena ʻaoʻao koʻikoʻi a i ʻole e holomua ana kāu maʻi maʻi me ka mālama ʻana, hiki i kāu kauka ke hoʻoponopono i kāu mahele, hoʻololi i ka papa hana, a i ʻole e hoʻololi i kahi lāʻau lapaʻau ʻē aʻe. ʻO ka hoʻoholo e hoʻomau a hoʻōki paha i ka azacitidine e hilinaʻi ana i kāu pane pilikino a me ka maikaʻi o kāu mālama ʻana i nā hopena ʻaoʻao.

ʻAʻole like me kekahi mau lāʻau lapaʻau maʻi maʻi i hāʻawi ʻia no ka manawa paʻa, ua hoʻomau pinepine ʻia ka azacitidine inā e hāʻawi ana i ka pōmaikaʻi me ka ʻole o ka hopena ʻaoʻao ʻae ʻole. E hana pū kāu hui oncology me ʻoe e hoʻoholo i ke ala maikaʻi loa no kāu kūlana.

He aha nā hopena ʻaoʻao o Azacitidine?

Hiki i ka Azacitidine ke hana i nā hopena ʻaoʻao no ka mea e pili ana i nā cell maʻi a me kekahi mau cell olakino e mahele wikiwiki ana. Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao me ka nānā pono ʻana a me ka mālama kākoʻo, a ʻike ka nui o nā maʻi e hiki iā lākou ke mālama i ke ola maikaʻi i ka wā e loaʻa ana ka lāʻau lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia ka luhi, ka nausea, a me nā hopena o ka pūnaewele injection e like me ka ʻulaʻula a i ʻole ka pehu. Hiki ke hana pinepine kēia i nā lā mua o kēlā me kēia pōʻaiapuni a hoʻomaikaʻi pinepine i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau.

Eia nā hopena ʻaoʻao āu e ʻike ai, i hoʻonohonoho ʻia mai ka mea maʻamau a hiki i ka liʻiliʻi:

• Luhi a me ka nāwaliwali, e pili ana i ka 80% o nā maʻi
• Nausea a me ka luaʻi, maʻamau ka maʻalahi a i ʻole ka maʻalahi
• Nā hopena o ka pūnaewele injection e like me ka ʻulaʻula, ka pehu, a i ʻole ka ʻeha
• Nā helu koko haʻahaʻa (anemia, nā keʻokeʻo keʻokeʻo haʻahaʻa, nā platelets haʻahaʻa)
• Pāpaʻa a i ʻole ka paʻa
• Hoʻemi ʻia ka ʻai
• Fiva, ʻoi loa i nā pōʻaiapuni mua
• ʻO ka ʻeha ʻiʻo a i ʻole ka hui
• ʻO ka ʻūlū a i ʻole ke poʻo
• Pōkole o ka hanu

E nānā pono kāu hui mālama ola iā ʻoe no kēia mau hopena a hiki ke hāʻawi i nā lāʻau lapaʻau a i ʻole nā hoʻolālā e kōkua i ka mālama ʻana iā lākou. ʻIke ka hapa nui o nā maʻi i nā hopena ʻaoʻao i ʻike nui ʻia i nā pōʻai mua a pinepine e lilo i mea hiki ke mālama ʻia i ka manawa.

Pono nā hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau i ka mālama olakino koke. Aia kēia mau mea i nā hōʻailona o ka maʻi koʻikoʻi (fiva kiʻekiʻe, nā anu, ka luhi nui), ke kahe koko ʻano ʻē a i ʻole ka ʻeha, ka nausea nui e pale ana iā ʻoe mai ka mālama ʻana i nā wai, a i ʻole ka pilikia o ka hanu.

I kekahi manawa, hiki i kekahi mau maʻi ke ʻike i nā pilikia koʻikoʻi e like me ka pneumonia, nā hopena ʻili koʻikoʻi, a i ʻole nā pilikia o ka puʻupaʻa. E kūkākūkā kāu kauka i kēia mau mea me ʻoe a wehewehe i nā hōʻailona ʻōlelo aʻo e nānā ai ma waena o nā lāʻau lapaʻau.

ʻO wai ka mea ʻaʻole pono e lawe iā Azacitidine?

ʻAʻole kūpono ʻo Azacitidine no nā mea a pau, a e loiloi pono kāu kauka inā palekana ia iā ʻoe e pili ana i kou olakino holoʻokoʻa a me ka mōʻaukala olakino. Pono ka lāʻau lapaʻau i kou kino e loaʻa i ka lawa o ka mālama ʻana e mālama i kāna hopena i ka hana ʻana o ke keʻena koko.

ʻAʻole pono ʻoe e loaʻa iā azacitidine inā he maʻi ʻoe iā ia a i ʻole mannitol (he mea i hoʻohana ʻia i ka injection). E akahele loa kāu kauka inā loaʻa iā ʻoe ka maʻi ate koʻikoʻi, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o kou kino e hana ai i ka lāʻau lapaʻau.

Pono kekahi mau kūlana i ka mālama hou a me ka nānā pono ʻana, ʻoiai ʻaʻole lākou e hoʻokaʻawale iā ʻoe mai ka lāʻau lapaʻau:

• Maʻi puʻupaʻa koʻikoʻi a i ʻole ka hilinaʻi dialysis
• Nā maʻi ikaika, ʻaʻole i hoʻomalu ʻia
• Maʻi puʻuwai koʻikoʻi a i ʻole ka puʻuwai i hala koke
• Nā helu koko haʻahaʻa loa ʻaʻole e hoʻomaikaʻi me ka mālama kākoʻo
• Hāpai a i ʻole ka hānai ʻana
• ʻO ka ʻoki nui hou a i ʻole ka hoʻōla ʻana i nā ʻeha
• Nā maʻi maʻi ʻē aʻe e pono ai ka lāʻau lapaʻau

E kau ana kāu kauka i kēia mau mea i nā pōmaikaʻi e hiki mai ana o ka lāʻau lapaʻau. I kekahi mau hihia, ʻo ka hoʻoponopono ʻana i kēia mau pilikia ma mua a i ʻole ka hāʻawi ʻana i ke kākoʻo hou aku hiki ke lilo i ka azacitidine i koho kūpono.

Inā ʻoe e hoʻolālā ana e hāpai a i ʻole e hānau keiki, e kūkākūkā me kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau. Hiki i ka Azacitidine ke hōʻeha i nā pēpē e ulu ana, a pono nā kāne a me nā wahine e hoʻohana i ka pale ʻana i ka hāpai ʻana i ka wā o ka lāʻau lapaʻau a no kekahi mau mahina ma hope.

Nā inoa inoa o Azacitidine

Loaʻa ka Azacitidine ma lalo o ka inoa inoa ʻo Vidaza, ʻo ia ka mea i kauoha pinepine ʻia o kēia lāʻau. Hele mai ʻo Vidaza ma ke ʻano he pauka i hui pū ʻia me ka wai sterile ma mua o ka injection, a loaʻa ia i nā ʻano subcutaneous a me intravenous.

Loaʻa nō hoʻi kahi ʻano waha hou i kapa ʻia ʻo Onureg (azacitidine tablets) no kekahi mau maʻi e kūpono ana no ka mālama ʻana ma hope o ka lāʻau lapaʻau mua. Hāʻawi kēia ʻano papa i kekahi mau maʻi e hoʻomau i ka lāʻau lapaʻau ma ka home ma mua o ka hele ʻana i ka hale lapaʻau no nā injections.

Loaʻa nō hoʻi nā mana generic o ka azacitidine injectable, hiki ke ʻoi aku ka maʻalahi o ke kumukūʻai me ka hāʻawi ʻana i nā pōmaikaʻi therapeutic like. Hiki i kāu ʻinikua a me ka hale kūʻai lāʻau lapaʻau ke hoʻopili i ka inoa inoa a i ʻole ka mana generic āu e loaʻa ai.

Me ka nānā ʻole i ka inoa inoa āu e loaʻa ai, ua like ka mea hana a me ka pono. E hōʻoia kāu hui mālama ola e loaʻa iā ʻoe ka formulation kūpono no kāu hoʻolālā lapaʻau.

Nā koho ʻē aʻe o Azacitidine

Nui nā lāʻau lapaʻau ʻē aʻe e hiki ke mālama i nā maʻi koko like, ʻoiai e hilinaʻi ka koho i kāu hōʻailona kikoʻī, ke olakino holoʻokoʻa, a me nā lāʻau lapaʻau ma mua. E noʻonoʻo kāu kauka i kēia mau koho ʻē aʻe inā ʻaʻole kūpono ka azacitidine a i ʻole e pau ka hana ʻana iā ʻoe.

ʻO Decitabine (Dacogen) kekahi mea hoʻohaʻahaʻa methylating e hana like me azacitidine. Hiki i kekahi poʻe maʻi i pane ʻole i kekahi ke pōmaikaʻi mai kekahi, ʻoiai ua like nā hopena ʻaoʻao a me nā hana.

ʻO nā koho lapaʻau ʻē aʻe e noʻonoʻo ai kāu kauka:

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• Venetoclax, hui pinepine ʻia me azacitidine no kekahi mau ʻano o AML
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• Lenalidomide (Revlimid) no nā ʻano MDS kikoʻī
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• Nā papa hana chemotherapy ikaika no nā maʻi ʻōpio a olakino
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• Mālama kākoʻo me nā hoʻoili koko a me nā mea ulu
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• Nā hoʻokolohua lapaʻau e noiʻi ana i nā lāʻau lapaʻau hou
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• Hoʻololi i ka iwi iwi no nā maʻi kūpono
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ʻO ke koho maikaʻi loa e pili ana i nā mea e like me kou makahiki, ke olakino holoʻokoʻa, nā hōʻailona genetic i loko o kāu mau maʻi maʻi, a me kāu mau makemake pilikino. E kūkākūkā kāu hui oncology i kēia mau koho me ʻoe inā ʻaʻole ʻo azacitidine ke koho kūpono a i ʻole ke hana ʻole.

Hiki i kekahi poʻe maʻi ke loaʻa i nā therapies hui pū me azacitidine me nā lāʻau lapaʻau ʻē aʻe, i kekahi manawa hiki ke ʻoi aku ka maikaʻi ma mua o kekahi lāʻau hoʻokahi.

ʻOi aku ka maikaʻi o Azacitidine ma mua o Decitabine?

ʻO Azacitidine a me decitabine nā mea hoʻohaʻahaʻa methylating e hana like, akā he mau ʻokoʻa ko lākou e hiki ai ke kūpono kekahi iā ʻoe ma mua o kekahi. ʻAʻole maopopo ka

Ua hōʻike nā noiʻi e ʻoi aku ka maikaʻi o ka azacitidine no kekahi mau ʻano o ka MDS, ʻoi aku hoʻi nā maʻi pilikia kiʻekiʻe. Akā, makemake ʻia ka decitabine no nā maʻi i pilikia i nā hopena o ka wahi injection a i ʻole makemake i ka lawelawe intravenous.

Ua like nā ʻaoʻao hopena ma waena o nā lāʻau ʻelua, akā, ua ʻae kekahi mau maʻi i kekahi ma mua o kekahi. E noʻonoʻo kāu kauka i kāu ʻano maʻi maʻi, nā lāʻau lapaʻau i hala, a me nā makemake pilikino i ke koho ʻana ma waena o lākou.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Azacitidine

He Palekana ka Azacitidine no nā Maʻi me ka Maʻi Puʻupaʻa?

Hiki ke hoʻohana ʻia ka Azacitidine i nā maʻi me ka maʻi puʻupaʻa maʻalahi a i ka waena, akā pono ia i ka nānā pono ʻana a me ka hoʻoponopono ʻana i ka mahele. E nānā kāu kauka i kāu hana puʻupaʻa maʻamau ma o nā hoʻokolohua koko a hiki ke hōʻemi i kāu mahele inā ʻaʻole hana maikaʻi kou puʻupaʻa.

Inā loaʻa iā ʻoe ka maʻi puʻupaʻa koʻikoʻi a i ʻole ma ka dialysis, e noʻonoʻo kāu kauka i nā pōmaikaʻi a me nā pilikia me ka akahele loa. Hiki ke wehe ʻia ka lāʻau lapaʻau e ka dialysis, no laila pono e hoʻonohonoho ʻia ka manawa o nā lāʻau lapaʻau me kāu papa dialysis.

He aha kaʻu e hana ai inā hoʻohana hewa au i ka nui o ka Azacitidine?

No ka mea, hāʻawi ʻia ka azacitidine e nā poʻe loea mālama ola i nā wahi i mālama ʻia, he mea maʻamau loa ka overdose ulia. Eia naʻe, inā manaʻo ʻoe ua loaʻa iā ʻoe ka nui o ka lāʻau lapaʻau a i ʻole e ʻike nei i nā hopena ʻaoʻao koʻikoʻi, e hoʻokaʻaʻike koke i kāu hui mālama ola a i ʻole e hele i ka lumi pilikia kokoke loa.

ʻO nā hōʻailona o ka overdose hiki ke komo i ka nausea a me ka luaʻi nui, ka luhi nui, ke kuni, ke kahe koko ʻano ʻē, a i ʻole ka pilikia o ka hanu. ʻAʻohe antidote kikoʻī no ka azacitidine, no laila e kālele ana ka lāʻau lapaʻau i ka mālama ʻana i nā hōʻailona a me ke kākoʻo ʻana i ka hoʻōla ʻana o kou kino.

He aha kaʻu e hana ai inā hala wau i kahi mahele o ka Azacitidine?

Inā ʻoe e hala i ka pahu azacitidine i hoʻonohonoho ʻia, e hoʻokaʻaʻike koke i kāu hui mālama ola e hoʻonohonoho hou. Mai hoʻāʻo e hoʻoponopono i nā lāʻau i hala ma ka lawe ʻana i nā lāʻau hou - he mea weliweli kēia a ʻaʻole ia e hoʻomaikaʻi i nā hopena o kāu mālama ʻana.

Hiki i kāu kauka ke hoʻoponopono i kāu papa hana lapaʻau a i ʻole e hoʻololi i kāu pōʻaiapuni ma muli o ka nui o nā lāʻau i hala iā ʻoe. He mea nui ka kūlike no ka pono, no laila e hoʻāʻo e mālama i nā manawa i hoʻonohonoho ʻia a pau a e kamaʻilio i nā paio hoʻonohonoho ma mua.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Azacitidine?

Pono ʻoe e hooki i ka azacitidine ma lalo o ke alakaʻi a kāu kauka. ʻAʻole like me kekahi mau lāʻau i lawe ʻia no ka manawa paʻa, ua hoʻomau pinepine ʻia ka azacitidine inā e kōkua ana ia i ka mālama ʻana i kāu maʻi maʻi a ke ʻae nei ʻoe iā ia.

E loiloi mau kāu kauka inā he pono ka lāʻau lapaʻau ma o nā hoʻokolohua koko, nā biopsies iwi iwi, a me ka nānā ʻana i kāu mau hōʻailona. Inā holomua kāu maʻi maʻi a i ʻole e lilo nā hopena ʻaoʻao i mea hiki ʻole ke mālama ʻia, e kūkākūkā kāu kauka i nā lāʻau lapaʻau ʻē aʻe a i ʻole nā koho mālama kākoʻo.

Hiki iaʻu ke loaʻa nā lāʻau lapaʻau i ka wā e lawe ana iā Azacitidine?

Pono ʻoe e pale i nā lāʻau lapaʻau ola i ka wā e lawe ana iā azacitidine no ka mea hiki i ka lāʻau lapaʻau ke hoʻonāwali i kāu ʻōnaehana pale. Aia kēia i nā lāʻau lapaʻau e like me ka lāʻau lapaʻau flu ola (nasal spray), MMR, a me nā lāʻau lapaʻau varicella (chickenpox).

Eia naʻe, palekana a paipai ʻia nā lāʻau lapaʻau i hoʻopau ʻia e like me ka pana flu, ka lāʻau lapaʻau pneumonia, a me nā lāʻau lapaʻau COVID-19. E aʻo aku kāu kauka iā ʻoe i nā lāʻau lapaʻau e loaʻa iā ʻoe a i ka manawa e loaʻa ai iā lākou no ka pale maikaʻi loa me ka hōʻemi ʻana i nā pilikia.