He aha ʻo Aztreonam: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Aztreonam he lāʻau antibiotic i kauoha ʻia e nā kauka e mālama i nā maʻi bacteria koʻikoʻi. No ka papa kūikawā o nā antibiotics i kapa ʻia ʻo monobactams, e hana ana i nā ʻano like ʻole mai ka penicillin a me nā antibiotics maʻamau.

Hāʻawi ʻia kēia lāʻau lapaʻau ma o ka IV (intravenous) laina a i ʻole he injection i loko o kou ʻiʻo. E hoʻohana maʻamau kāu hui mālama ola iā aztreonam ke ʻaʻole i hana nā antibiotics ʻē aʻe a i ʻole ke loaʻa iā ʻoe kahi maʻi i hana ʻia e nā bacteria e kūʻē i nā lāʻau lapaʻau ʻē aʻe.

No ke aha e hoʻohana ʻia ai ʻo Aztreonam?

Hoʻomaʻamaʻa ʻo Aztreonam i nā maʻi bacteria koʻikoʻi i hiki ke hoʻoweliweli i ke ola inā ʻaʻole i mālama ʻia. Kauoha nā kauka iā ia ke pono lākou i kahi antibiotic ikaika e hiki ke hōʻea i nā wahi i maʻi ʻia ma o kou kahe koko.

Hana maikaʻi kēia lāʻau lapaʻau i kekahi mau ʻano bacteria i kapa ʻia ʻo gram-negative bacteria. Loaʻa i kēia mau bacteria kahi pūpū pale e paʻakikī ai lākou e mālama me nā antibiotics maʻamau.

ʻO nā maʻi maʻamau i mālama ʻia me aztreonam e pili ana:

• Pneumonia a me nā maʻi māmā koʻikoʻi ʻē aʻe
• Nā maʻi ʻōnaehana urinary i laha i kou mau puʻupaʻa
• Nā maʻi ʻōpū, me nā mea e pili ana i kou ʻōpū a i ʻole ke ake
• Nā maʻi ʻili a me nā ʻiʻo palupalu i hele hohonu
• Nā maʻi koko (sepsis)
• Nā maʻi iwi a me nā hui

Hiki nō hoʻi i kāu kauka ke hoʻohana iā aztreonam inā he maʻi ʻoe i ka penicillin a i ʻole nā ​​antibiotics beta-lactam ʻē aʻe. Manaʻo ʻia he palekana no ka poʻe me kēia mau maʻi maʻi no ka mea he ʻano kemika ʻokoʻa.

Pehea e hana ai ʻo Aztreonam?

ʻO Aztreonam kahi antibiotic ikaika e hana ana ma ka wāwahi ʻana i nā paia cell o nā bacteria. E noʻonoʻo i nā paia cell bacterial e like me ka pūpū pale a puni ka hua - ke hōʻino ʻo aztreonam i kēia pūpū, ʻaʻole hiki i ka bacteria ke ola.

Ke kālele nei kēia lāʻau lapaʻau i kahi enzyme i kapa ʻia ʻo transpeptidase e pono ai nā bacteria e kūkulu a mālama i ko lākou paia cell. Ke ālai ʻo aztreonam i kēia enzyme, hāʻule maoli nā bacteria a make.

ʻO ka mea e hana kūikawā ai ʻo aztreonam, ʻo ia ka hopena i kekahi mau ʻano bacteria. He mea maikaʻi loa ia i nā bacteria gram-negative akā ʻaʻole ia e hana i nā bacteria gram-positive a i ʻole nā fungi. Hiki i kēia hana i kālele ʻia ke kōkua i ka wā e ʻike pono ai kāu kauka i ke ʻano o ka maʻi āu e loaʻa nei.

Pehea wau e lawe ai iā Aztreonam?

Hāʻawi mau ʻia ʻo Aztreonam e nā poʻe loea mālama ola i loko o kahi haukapila a i ʻole ke keʻena lapaʻau. ʻAʻole ʻoe e lawe i kēia lāʻau lapaʻau ma ka home no ka mea pono e hoʻomākaukau hou ʻia a hāʻawi ʻia ma o ka laina IV a i ʻole ka injection.

E hāʻawi kāu kahu hānai a kauka paha iā ʻoe i ka aztreonam ma o ka vein (intravenously) a i ʻole ma ke ʻano he injection i loko o kahi ʻiʻo nui, maʻamau i kou ʻūhā a i ʻole ka ʻūhā. ʻOi aku ka maʻamau o ke ʻano IV no nā maʻi koʻikoʻi no ka mea e komo koke ai ka lāʻau lapaʻau i loko o kou kahe koko.

ʻAʻole pono ʻoe e hopohopo e pili ana i ka lawe ʻana i kēia lāʻau lapaʻau me ka meaʻai no ka mea e hele pololei ana i loko o kou kahe koko. Eia naʻe, ʻo ka noho ʻana i ka wai maikaʻi ma ka inu ʻana i ka wai nui hiki ke kōkua i kou mau puʻupaʻa e hana i ka lāʻau lapaʻau me ka ʻoi aku ka maikaʻi.

Hāʻawi ʻia ka lāʻau lapaʻau i kēlā me kēia 6 a 12 mau hola, ma muli o ke koʻikoʻi o kāu maʻi a me ke ʻano o kou kino e pane ai i ka lāʻau. E nānā pono kāu hui mālama ola iā ʻoe a hiki ke hoʻoponopono i ka manawa ma muli o kāu holomua.

Pehea ka lōʻihi e lawe ai au iā Aztreonam?

Aia ka lōʻihi o kāu lapaʻau aztreonam i ke ʻano a me ke koʻikoʻi o kāu maʻi. Loaʻa i ka hapa nui o nā kānaka kēia lāʻau lapaʻau no 7 a 14 mau lā, akā pono paha kekahi mau maʻi i ka lapaʻau lōʻihi.

E hoʻoholo kāu kauka i ka lōʻihi pololei ma muli o nā kumu he nui. Aia kēia i ka wikiwiki o ka pane ʻana o kāu maʻi, ke ʻano o ka bacteria e hana nei i ka pilikia, a me kou kūlana olakino holoʻokoʻa.

No ka maʻi pneumonia a i ʻole nā maʻi o ka māmā, pono paha ʻoe i ka aztreonam no 10 a 14 mau lā. Pono pinepine nā maʻi o ka ʻōnaehana urinary i 7 a 10 mau lā o ka lapaʻau. ʻO nā maʻi paʻakikī e like me nā mea i loko o kou ʻōpū a i ʻole nā iwi e pono ai ka lapaʻau no kekahi mau pule.

He mea nui e hoʻopau i ka papa lapaʻau piha inā hoʻomaka ʻoe e maikaʻi. ʻO ka hooki ʻana i ka antibiotic i ka wā mua e hiki ai i ka maʻi ke hoʻi mai me ka ikaika a hiki ke pale i ka lapaʻau.

He aha nā hopena ʻaoʻao o Aztreonam?

E like me nā lāʻau lapaʻau a pau, hiki i ka aztreonam ke hana i nā hopena ʻaoʻao, ʻoiai he nui ka poʻe e ʻae maikaʻi iā ia. ʻO ka hapa nui o nā hopena ʻaoʻao he maʻalahi a hele aku ke pau kāu lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai:

• ʻEha, pehu, a i ʻole ʻulaʻula ma kahi o ka injection
• Nausea a i ʻole ka ʻōpū
• Pāpaʻa
• Poʻo
• ʻĀwili
• Pāpaʻa ʻili

Hoʻomaikaʻi maʻamau kēia mau hōʻailona i ka wā e hoʻoponopono ai kou kino i ka lāʻau. E nānā kāu hui mālama ola iā ʻoe no nā hopena a hiki ke hāʻawi i nā lapaʻau e kōkua i ka mālama ʻana i nā hopena ʻaoʻao ʻoluʻolu ʻole.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi e pono ai ka lāʻau lapaʻau koke:

• Nā hopena maʻi koʻikoʻi me ka pilikia o ka hanu ʻana a i ʻole ka pehu ʻana o kou maka a me kou ʻāʻī
• Pāpaʻa koʻikoʻi i loaʻa paha ke koko
• ʻO ka ʻeha a i ʻole ke kahe ʻana
• Melemele o kou ʻili a i ʻole nā maka
• Huikau a i ʻole nā hopu

Aia kekahi mau hopena ʻaoʻao kakaʻikahi akā koʻikoʻi e hana ʻia ma lalo o 1% o ka poʻe e lawe ana i ka aztreonam. Pākuʻi ʻia kēia mau mea i nā hopena ʻili koʻikoʻi, nā pilikia o ke ake, a me nā loli i kāu helu keʻena koko. E nānā kāu hui lapaʻau i kēia mau mea ma o ka nānā mau a me nā hoʻokolohua koko.

ʻO wai ka mea pono ʻole e lawe i ka Aztreonam?

He palekana ʻo Aztreonam no ka hapa nui o nā kānaka, akā aia kekahi mau kūlana e koho ai kāu kauka i kahi lāʻau antibiotic ʻē aʻe. ʻO ka hopohopo nui inā ua loaʻa iā ʻoe kahi hopena maʻi i ka aztreonam i ka wā ma mua.

Pono paha nā kānaka me ka maʻi kīkī koʻikoʻi i nā ʻano lāʻau i hoʻoponopono ʻia a i ʻole ka nānā ʻana. Ma muli o ke kōkua ʻana o kou mau kīkī i ka wehe ʻana i ka aztreonam mai kou kino, hiki i ka hana kīkī i hoʻemi ʻia ke kumu e kūkulu ai ka lāʻau lapaʻau i nā pae kiʻekiʻe.

E akahele nō hoʻi kāu kauka inā loaʻa iā ʻoe:

• He moʻolelo o ka maʻi ate koʻikoʻi
• He maʻi koko a i ʻole ka helu platelet haʻahaʻa
• He moʻolelo o nā hopu a i ʻole nā maʻi lolo
• ʻO ka maʻi ʻōpū inflammatory e like me ka maʻi o Crohn a i ʻole ulcerative colitis

Pono ka hāpai ʻana a me ka hānai ʻana i ka umauma i ka noʻonoʻo kūikawā. ʻOiai ua manaʻo ʻia ʻo aztreonam he palekana i ka wā hāpai, e kaupaona kāu kauka i nā pōmaikaʻi e kūʻē i nā pilikia e hiki mai ana i kāu pēpē.

Nā inoa inoa Aztreonam

Loaʻa ʻo Aztreonam ma lalo o nā inoa inoa like ʻole, ʻo Azactam ka mea maʻamau ma ʻAmelika Hui Pū ʻIa. Hiki nō hoʻi iā ʻoe ke ʻike iā ia i kapa ʻia ʻo Cayston, he ʻano inhaled kūikawā i hoʻohana ʻia no nā maʻi māmā i nā kānaka me ka cystic fibrosis.

Loaʻa nō hoʻi nā mana generic o aztreonam a hana like ka maikaʻi e like me nā mana inoa inoa. E hoʻohana kāu haukapila a i ʻole ke keʻena lapaʻau i ka mana i loaʻa iā lākou, a loaʻa i nā ʻano āpau ka mea hana like.

Nā koho ʻē aʻe o Aztreonam

Inā ʻaʻole ʻo aztreonam ke koho kūpono no kāu maʻi, he nui nā lāʻau antibiotic ikaika ʻē aʻe e noʻonoʻo ai kāu kauka. ʻO ke koho maikaʻi loa e pili ana i ke ʻano o ka bacteria e hana nei i kāu maʻi a me kāu moʻolelo olakino.

ʻO nā koho maʻamau e pili ana i nā fluoroquinolones e like me ciprofloxacin a i ʻole levofloxacin, hiki ke mālama i nā maʻi he nui e like me aztreonam. No kekahi mau maʻi, hiki i kāu kauka ke koho i nā aminoglycosides e like me gentamicin a i ʻole tobramycin.

ʻO nā lāʻau antibiotic carbapenem e like me meropenem a i ʻole imipenem kekahi koho no nā maʻi koʻikoʻi. Hana kēia mau lāʻau i ka nui o nā bacteria ma mua o aztreonam akā loaʻa paha nā hopena ʻē aʻe.

Na kāu kauka e koho i ke koho maikaʻi loa e pili ana i kāu kūlana kikoʻī, me nā maʻi āu i loaʻa a me nā hopena o nā hoʻokolohua e ʻike ai i nā bacteria e hana ana i kāu maʻi.

Ua ʻoi aku ka maikaʻi o Aztreonam ma mua o Ceftriaxone?

He mau antibiotic ikaika ʻo Aztreonam a me ceftriaxone, akā hana lākou i nā ʻano bacteria like ʻole. ʻAʻole ʻoi aku ka maikaʻi o kekahi - pili ke koho kūpono i kāu maʻi kikoʻī a me ke kūlana olakino.

No ka papa i kapa ʻia ʻo cephalosporins ʻo Ceftriaxone a hana i nā bacteria gram-positive a me gram-negative. Hana kēia i mea pono no ka nui o nā maʻi ke ʻaʻole maopopo i nā kauka i ke ʻano o nā bacteria a lākou e mālama nei.

ʻO Aztreonam, ma kekahi ʻaoʻao, hana wale nō i nā bacteria gram-negative akā he mea maikaʻi loa ia i kēia mau ʻano. Koho pinepine ʻia ke hana ʻole nā antibiotic ʻē aʻe a i ʻole ke maʻi ʻoe i nā lāʻau lapaʻau ʻano penicillin.

ʻO ka pōmaikaʻi nui o aztreonam ʻo ia kona palekana no ka poʻe me nā maʻi penicillin. Hiki i ka Ceftriaxone ke hana i nā hopena maʻi i ka poʻe i maʻi i ka penicillin, ʻoiai ʻo aztreonam ka mea palekana no kēia mau kānaka.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Aztreonam

Q1. He palekana ʻo Aztreonam no ka poʻe me ka maʻi kīkī?

Hiki ke hoʻohana ʻia ʻo Aztreonam i ka poʻe me ka maʻi kīkī, akā e hoʻoponopono paha kāu kauka i ka mahele a nānā pono iā ʻoe. No ka mea, kōkua kou mau puʻupaʻa i ka wehe ʻana i ka aztreonam mai kou kino, ʻo ka hana kīkī i hōʻemi ʻia ʻo ia ka lāʻau lapaʻau e noho lōʻihi ana i loko o kou ʻōnaehana.

E nānā kāu hui mālama ola i kāu hana puʻupaʻa me nā hoʻokolohua koko ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau a e hoʻomau paha i ka nānā ʻana i kāu papa o nā lāʻau antibiotic. Hiki iā lākou ke hāʻawi iā ʻoe i nā mea liʻiliʻi a i ʻole e hoʻokaʻawale i nā mea hou aku i mea e pale ai i ka lāʻau lapaʻau mai ka hōʻiliʻili ʻana i nā pae pōʻino.

Q2. He aha kaʻu e hana ai inā he hopena maʻi ʻaʻai koʻu i ka Aztreonam?

Inā loaʻa iā ʻoe nā hōʻailona o ka hopena maʻi ʻaʻai i ka wā e loaʻa ana iā aztreonam, e haʻi koke i kāu hui mālama ola. Hiki ke mālama pinepine ʻia nā hopena maʻalahi e like me ka ʻili ʻili me nā antihistamines i ka wā e hoʻomau ana i kāu lāʻau lapaʻau.

Pono nā hopena maʻi ʻaʻai koʻikoʻi i ka lāʻau lapaʻau koke. ʻO nā hōʻailona e komo pū ana me ka pilikia o ka hanu ʻana, ka pehu ʻana o kou maka a i ʻole ka ʻāʻī, ka ʻūlū nui, a i ʻole ka puʻuwai wikiwiki. Ma muli o ka loaʻa ʻana o ka aztreonam i loko o kahi hoʻonohonoho olakino, ua mākaukau kāu hui mālama ola e mālama i kēia mau kūlana me ka wikiwiki a me ka pono.

Q3. He aha kaʻu e hana ai inā e poina iaʻu kahi mahele o Aztreonam?

No ka mea, hāʻawi ʻia ka aztreonam e nā poʻe loea mālama ola i loko o kahi haukapila a i ʻole ke keʻena lapaʻau, ʻaʻole pono ʻoe e hopohopo e pili ana i ka poina ʻana i nā mahele iā ʻoe iho. E hahai ana kāu hui lapaʻau i kahi papa hana koʻikoʻi e hōʻoiaʻiʻo ai e loaʻa iā ʻoe kēlā me kēia mahele i ka manawa kūpono.

Inā no kekahi kumu e lohi ai kahi mahele ma muli o nā kaʻina hana lapaʻau a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe, e hoʻoponopono kāu hui mālama ola i kāu papa hana. E hōʻoia lākou e loaʻa iā ʻoe ka papa piha o ka lāʻau lapaʻau e pono ai kāu maʻi.

Q4. I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Aztreonam?

Na kāu kauka e hoʻoholo i ka manawa e hooki ai i kāu lāʻau lapaʻau aztreonam ma muli o ka maikaʻi o ka pane ʻana o kāu maʻi. E nānā lākou i nā mea e like me kāu mau hōʻailona, ​​nā hopena hoʻāʻo koko, a me nā haʻawina kiʻi e hoʻoholo ai i ka wā e mālama ʻia ai ka maʻi.

Mai noi e hooki i ka lāʻau lapaʻau i ka wā mua, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi. Hiki i nā maʻi bacteria ke hoʻi mai me ka ikaika inā ʻaʻole i hoʻopau loa ʻia, a ʻo ka hooki ʻana i nā antibiotics i ka wā mua hiki ke alakaʻi i ke kūpaʻa antibiotic.

Nīnau 5. Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Aztreonam?

ʻOiai ʻaʻole he pilina pololei o ka aztreonam me ka waiʻona, ʻoi aku ka maikaʻi o ka pale ʻana i ka inu ʻana i ka wā e mālama ʻia nei ʻoe no kahi maʻi koʻikoʻi. Hiki i ka waiʻona ke keakea i ka hiki o kou kino ke hakakā i ka maʻi a hiki ke hoʻonui i kekahi mau hopena ʻaoʻao e like me ka nausea a i ʻole ka ʻūlū.

Pono kou kino i kona ikaika a me nā kumuwaiwai a pau e hakakā i ka maʻi a hoʻōla. Hiki i ka waiʻona ke hoʻopilikia i ka hiki o kou ate ke hana i nā lāʻau lapaʻau a hiki ke keakea i kāu hiamoe a me ka hoʻōla. E kālele ana i ka noho ʻana i ka wai me ka wai a me ka hoʻomaha nui.