He aha ka Bempedoic Acid: Nā Hoʻohana, Nā Ana, Nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau hoʻohaʻahaʻa cholesterol hou ka Bempedoic acid e kōkua ana i ka hoʻohaʻahaʻa ʻana i nā pae cholesterol LDL

Ua manaʻo ʻia ka lāʻau lapaʻau he mea maikaʻi i ka hoʻohaʻahaʻa ʻana i ka cholesterol LDL, e hoʻohaʻahaʻa ana i nā pae ma kahi o 15-25% ke hoʻohana ʻia wale nō. Ke hui pū ʻia me ka statin, hiki i ka hopena hoʻohaʻahaʻa cholesterol ke ʻoi aku ka nui, e kōkua ana iā ʻoe e hōʻea i kāu mau pae i manaʻo ʻia me ka maikaʻi.

ʻO kekahi mea kū hoʻokahi o ka waikawa bempedoic ʻo ia ka mea a nā kauka e kapa ai he "prodrug." ʻO ia hoʻi, lilo ia i mea hana ma hope o ka hana ʻana o kou kino, ʻo ia hoʻi i loko o ke ake kahi e hana ʻia ai ka cholesterol. Hiki i kēia hana i manaʻo ʻia ke kōkua i ka hōʻemi ʻana i kekahi o nā hopena ʻaoʻao e pili ana i ka ʻiʻo e hiki ke hana me nā lāʻau cholesterol ʻē aʻe.

Pehea wau e lawe ai i ka waikawa Bempedoic?

Lawe ʻia ka waikawa Bempedoic i hoʻokahi manawa i ka lā ma ke ʻano he papa 180mg, a hiki iā ʻoe ke lawe me ka ʻai ʻole a i ʻole. ʻIke ka hapa nui o nā kānaka he maʻalahi ke hoʻomanaʻo i ka wā e lawe ai lākou i ka manawa like i kēlā me kēia lā, e like me ka ʻaina kakahiaka a i ʻole ka ʻaina ahiahi.

Pono ʻoe e ale i ka papa holoʻokoʻa me ke aniani wai. Mai ʻoki, nau, a wāwahi paha i ka papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka lawe ʻana a me ka hana ʻana o ka lāʻau e kou kino.

Inā ʻoe e lawe ana i nā lāʻau ʻē aʻe, ʻoiai nā mea hoʻoheheʻe koko e like me ka warfarin, pono paha i kāu kauka e nānā pono iā ʻoe. Hiki i ka waikawa Bempedoic ke hoʻonui i nā hopena o kekahi mau mea hoʻoheheʻe koko, no laila he mea nui ka manawa a me ka hoʻonohonoho ʻana me kāu mea mālama ola.

Pehea ka lōʻihi e lawe ai au i ka waikawa Bempedoic?

ʻO ka waikawa Bempedoic ka mea maʻamau he lāʻau lōʻihi e pono ai ʻoe e lawe mau e mālama i kāna mau pono hoʻohaʻahaʻa cholesterol. Pono ka hapa nui o nā kānaka e lawe ia no nā mahina a i ʻole nā makahiki, e like me nā lāʻau cholesterol ʻē aʻe.

E nānā paha kāu kauka i kāu mau pae cholesterol ma hope o 8-12 mau pule o ka mālama ʻana e ʻike i ka maikaʻi o ka hana ʻana o ka lāʻau. Ma muli o kēia mau hopena, hiki iā lākou ke hoʻoponopono i kāu mahele a i ʻole e ʻōlelo i nā lāʻau lapaʻau hou e kōkua iā ʻoe e hōʻea i kāu mau pahuhopu cholesterol.

He mea nui ʻaʻole e hooki koke i ka lawe ʻana i ka waikawa bempedoic me ka ʻole e kamaʻilio mua me kāu kauka. Inā e hooki ʻoe i ka lāʻau lapaʻau, e hoʻi paha kou pae cholesterol i ko lākou pae kiʻekiʻe mua, hiki ke hoʻonui i kou pilikia o nā pilikia o ka naʻau i ka wā.

He aha nā hopena ʻaoʻao o ka waikawa Bempedoic?

Hiki i ka hapa nui o nā kānaka ke ʻae maikaʻi i ka waikawa bempedoic, akā e like me nā lāʻau lapaʻau a pau, hiki iā ia ke hana i nā hopena ʻaoʻao i kekahi poʻe. ʻO ka lono maikaʻi, ʻaʻole maʻamau nā hopena ʻaoʻao koʻikoʻi, a ʻaʻole nui ka poʻe i ʻike i nā hopena ʻaoʻao.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike, me ka noʻonoʻo ʻana e pili ana kēia mau mea i kahi pākēneka liʻiliʻi wale nō o ka poʻe e lawe ana i ka lāʻau:

• Nā maʻi o ka ʻōnaehana hanu luna (e like me ke anu maʻamau)
• Nā ʻiʻo ʻiʻo a i ʻole ka ʻeha, ʻoiai ʻoi aku ka maʻalahi ma mua o nā statins
• Nā pae waikawa uric kiʻekiʻe, hiki i kāu kauka ke nānā me nā hoʻokolohua koko
• ʻEha hope a i ʻole nā ʻeha kino maʻamau
• ʻEha ʻōpū a i ʻole ka hōʻoluʻolu
• Bronchitis a i ʻole ka ʻu

He maʻalahi kēia mau hopena ʻaoʻao a pinepine e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau. Inā ʻoe e ʻike i nā hōʻailona paʻa a i ʻole nā hōʻailona hoʻoluhi, mai kānalua e kūkākūkā me kāu mea mālama ola.

Aia kekahi mau hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e koi ai i ka lāʻau lapaʻau koke. ʻOiai he kakaikahi kēia, he mea nui e ʻike iā lākou:

• Nā hōʻailona o nā pilikia tendon, e like me ka ʻeha nui koke a i ʻole ka hiki ʻole ke hoʻoneʻe i kahi hui
• ʻEha ʻiʻo nui a i ʻole nāwaliwali ʻaʻole e hoʻomaikaʻi
• Nā hōʻailona o ka gout, me ka ʻeha hui koke a nui a me ka pehu
• Luhi a i ʻole nāwaliwali ʻano ʻē e mau ana

Inā ʻoe e ʻike i kekahi o kēia mau hōʻailona koʻikoʻi, e kelepona koke i kāu kauka. Hiki iā lākou ke kōkua i ka hoʻoholo ʻana inā pili nā hōʻailona i ka lāʻau a hoʻoponopono i kāu hoʻolālā lapaʻau inā pono.

ʻO wai ka mea ʻaʻole pono e lawe i ka waikawa Bempedoic?

ʻAʻole kūpono ka waikawa bempedoic no nā mea a pau, a e noʻonoʻo pono kāu kauka i kāu mōʻaukala olakino ma mua o ka kau ʻana. Aia kekahi mau kūlana a me nā kūlana kahi e pale ʻia ai kēia lāʻau a i ʻole e hoʻohana ʻia me ka akahele.

ʻAʻole pono ʻoe e lawe i ka waikawa bempedoic inā he maʻi ate koʻikoʻi kou a i ʻole inā hōʻike nā hoʻokolohua hana ate i nā mea ʻino. No ka mea e hana ʻia ka lāʻau e ke ake, hiki i ka hana ate i hoʻopilikia ʻia ke hoʻopilikia i ke ʻano o kou kino e mālama ai i ka lāʻau.

Inā hāpai ʻoe, e hoʻolālā ana e hāpai, a i ʻole e hānai ana i ka waiū, ʻaʻole i ʻōlelo ʻia ka waikawa bempedoic. ʻAʻole i hoʻokumu ʻia ka palekana o kēia lāʻau i ka wā hāpai a me ka hānai ʻana i ka waiū, no laila e ʻōlelo paha kāu kauka i nā ala ʻē aʻe e mālama ai i kāu cholesterol i kēia mau manawa.

ʻO ka poʻe me ka mōʻaukala o nā pilikia tendon a i ʻole kekahi mau kūlana genetic e pili ana i ka hana ʻana o ka ʻiʻo e pono paha i ka nānā kūikawā a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe. E kūkākūkā kāu kauka i kēia mau mea me ʻoe e pili ana i kāu mōʻaukala olakino.

Nā inoa inoa o ka waikawa Bempedoic

Loaʻa ka waikawa Bempedoic ma lalo o ka inoa inoa Nexletol ke hoʻohana wale ʻia. ʻO kēia ke ʻano i kauoha pinepine ʻia o ka lāʻau lapaʻau āu e hālāwai ai ma ka hale kūʻai lāʻau lapaʻau.

Aia kekahi lāʻau hui i kapa ʻia ʻo Nexlizet, aia ka waikawa bempedoic a me ka ezetimibe (kekahi lāʻau hoʻohaʻahaʻa cholesterol). Hiki i kāu kauka ke kauoha i kēia hui inā pono ʻoe i nā pōmaikaʻi o nā lāʻau lapaʻau ʻelua e hiki ai i kāu mau pahuhopu cholesterol.

Loaʻa i nā inoa inoa ʻelua ka mea hana like, akā hāʻawi ka mana hui i ka mana hoʻohaʻahaʻa cholesterol hou ma ka pale ʻana i ka absorption cholesterol i loko o kou ʻōpū a me ka hōʻemi ʻana i ka hana cholesterol i loko o kou ake.

Nā koho ʻē aʻe o ka waikawa Bempedoic

Inā ʻaʻole kūpono ka waikawa bempedoic iā ʻoe, aia kekahi mau lāʻau lapaʻau hoʻohaʻahaʻa cholesterol ʻē aʻe e noʻonoʻo ai kāu kauka. Aia ke koho i kāu kūlana kikoʻī, nā maʻi olakino ʻē aʻe, a me ke ʻano o kāu pane ʻana i nā lāʻau lapaʻau ma mua.

Noho mau nā statins i ka lāʻau lapaʻau mua no ka hapa nui o ka poʻe me ka cholesterol kiʻekiʻe. Aia kēia mau lāʻau lapaʻau e like me atorvastatin, simvastatin, a me rosuvastatin. He maikaʻi loa lākou a ua aʻo maikaʻi ʻia, ʻoiai ke ʻike nei kekahi poʻe i nā hopena ʻaoʻao e pili ana i ka ʻiʻo.

ʻO Ezetimibe kekahi koho ʻē aʻe e hana ana ma ka pale ʻana i ka absorption cholesterol i loko o kou ʻōpū. Hoʻohana pinepine ʻia ia me nā statins a i ʻole he koho ʻē aʻe no ka poʻe hiki ʻole ke ʻae i nā statins. ʻO nā mea pale PCSK9 he mau lāʻau lapaʻau hou aʻe, ʻoi aku ka ikaika i hāʻawi ʻia e ka injection, i mālama ʻia no ka poʻe me ka cholesterol kiʻekiʻe loa a i ʻole nā ​​maʻi genetic.

E hana pū kāu kauka me ʻoe e ʻimi i ke ala maikaʻi loa e pili ana i kāu pae cholesterol, nā mea pilikia, a me nā makemake pilikino. I kekahi manawa, ʻoi aku ka maikaʻi o ka hui pū ʻana o nā lāʻau lapaʻau ma mua o kekahi lāʻau hoʻokahi.

Ua ʻoi aku ka maikaʻi o ka waikawa Bempedoic ma mua o Statins?

Hana ʻokoʻa ka waikawa Bempedoic a me nā statins a loaʻa iā lākou nā pono ponoʻī, no laila ʻaʻole pono ka mea e

He mea maikaʻi ʻo Bempedoic acid, ʻoi loa no nā kānaka e ʻehaʻeha ana nā ʻiʻo me nā statins. ʻAʻole paha e loaʻa nā hopena ʻaoʻao e pili ana i nā ʻiʻo, e lilo ana i mea koho nui no nā maʻi statin-intolerant. He hana maikaʻi nō hoʻi ia me nā statins no nā kānaka e pono ai ka hoʻēmi ʻana i ka cholesterol.

E noʻonoʻo kāu kauka i nā mea e like me kāu pae cholesterol, ka pilikia o ka maʻi puʻuwai, nā ʻike lāʻau i hala, a me nā maʻi olakino ʻē aʻe i ka wā e hoʻoholo ai i ka lāʻau lapaʻau a i ʻole ka hui pū ʻana o nā lāʻau lapaʻau i kūpono iā ʻoe.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Bempedoic Acid

He Palekana anei ʻo Bempedoic Acid no nā Kānaka me ka maʻi diabetes?

Ua manaʻo ʻia ʻo Bempedoic acid he palekana no nā kānaka me ka maʻi diabetes, a he mea nui ka mālama ʻana i ka cholesterol inā he maʻi diabetes kāu no ka mea e hoʻonui ai i kou pilikia o ka maʻi puʻuwai. Eia naʻe, e nānā pono kāu kauka iā ʻoe no ka mea hiki i ka maʻi diabetes ke hoʻopilikia i ke ʻano o ka hana ʻana o kou kino i nā lāʻau lapaʻau.

Hōʻike kekahi mau haʻawina e hiki i ka bempedoic acid ke loaʻa kahi hopena maikaʻi liʻiliʻi i nā pae kō koko, ʻoiai ʻaʻole kēia kāna kumu nui. E hoʻomau kāu kauka i ka nānā ʻana i kāu mālama ʻana i ka maʻi diabetes me kāu mālama ʻana i ka cholesterol e hōʻoia i ka mālama maikaʻi ʻana i nā kūlana ʻelua.

He aha kaʻu e hana ai inā ua lawe hewa au i ka nui o Bempedoic Acid?

Inā ua lawe hewa ʻoe i ka nui o kāu lāʻau bempedoic acid i kauoha ʻia, mai hopohopo. ʻOiai pono ʻoe e pale i ka lawe ʻana i nā lāʻau hou, ʻaʻole paha e hōʻeha nui ka lāʻau pālua i kekahi manawa i ka hapa nui o nā kānaka.

E hoʻokaʻaʻike i kāu kauka a i ʻole ka mea kūʻai lāʻau lapaʻau no ke alakaʻi ʻana, ʻoi loa inā ua lawe ʻoe i ka nui o ka lāʻau i kauoha ʻia a i ʻole e ʻike nei ʻoe i nā hōʻailona maʻamau ʻole. Hiki iā lākou ke aʻo iā ʻoe inā pono ka nānā ʻana a i ʻole nā hana kikoʻī e pili ana i ka nui o ka lāʻau hou āu i lawe ai.

He aha kaʻu e hana ai inā ua hala au i kahi lāʻau o Bempedoic Acid?

Inā poina iā ʻoe ka lāʻau bempedoic acid, e lawe koke iā ia ke hoʻomanaʻo ʻoe, ke ʻole kokoke ka manawa no kāu lāʻau i hoʻonohonoho ʻia. I kēlā hihia, e lele i ka lāʻau i poina a e hoʻomau me kāu papa hana maʻamau.

Mai lawe i ʻelua lāʻau i ka manawa hoʻokahi e hoʻoponopono ai i ka lāʻau i poina, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao. Inā poina pinepine ʻoe i nā lāʻau, e noʻonoʻo e hoʻonohonoho i kahi hoʻomanaʻo i kēlā me kēia lā a i ʻole e lawe i kāu lāʻau i ka manawa like i kēlā me kēia lā ma ke ʻano he ʻāpana o kāu hana maʻamau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Bempedoic Acid?

Pono ʻoe e hooki i ka lawe ʻana i ka bempedoic acid ma lalo o ke alakaʻi a kāu kauka. He lāʻau lōʻihi kēia, a ʻo ka hooki ʻana iā ia me ka wikiwiki e hoʻihoʻi hou i kou pae cholesterol i ko lākou pae kiʻekiʻe mua.

Hiki i kāu kauka ke noʻonoʻo e hooki a hoʻololi paha i kāu lāʻau inā loaʻa iā ʻoe nā hopena ʻaoʻao nui, inā e loli ana kāu mau pahuhopu cholesterol, a i ʻole inā e ulu ana nā kūlana olakino ʻē aʻe e hoʻemi ai i ka kūpono o ka lāʻau. E hana pū lākou me ʻoe e hōʻoia i loaʻa iā ʻoe kahi hoʻolālā ʻē aʻe kūpono no ka mālama ʻana i kāu cholesterol.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Bempedoic Acid?

ʻAe ʻia ka inu ʻana i ka waiʻona i ka wā e lawe ana i ka bempedoic acid, akā he mea nui e kūkākūkā i kēia me kāu kauka. Hiki i ka waiʻona ke hoʻopilikia i kāu hana ate a me nā pae cholesterol, no laila e makemake kāu kauka e hōʻoia i ka palekana o ka hoʻohana ʻana i ka waiʻona i kāu hoʻolālā lapaʻau holoʻokoʻa.

Inā he pilikia kou ate a i ʻole e lawe i nā lāʻau ʻē aʻe e launa pū me ka waiʻona, hiki i kāu kauka ke ʻōlelo e kaupalena a pale loa i ka waiʻona. E ʻoiaʻiʻo me kāu mea mālama ola e pili ana i kāu ʻai ʻana i ka waiʻona i hiki iā lākou ke hāʻawi iā ʻoe i ke alakaʻi kūpono loa no kou kūlana.