He aha ʻo Bevacizumab-awwb: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Bevacizumab-awwb he lāʻau lapaʻau maʻi ʻaʻai biosimilar e kōkua ana i ka mālama ʻana i kekahi mau ʻano maʻi ʻaʻai ma ka pale ʻana i ka ulu ʻana o nā kīʻaha koko i nā ʻōpū. He antibody i hana ʻia i loko o ka hale hana e hoʻohālike i nā protein immune maoli o kou kino, i hoʻolālā ʻia e hoʻopau i nā cell maʻi ʻaʻai i nā meaʻai e pono ai lākou e ulu a laha.

No kēia lāʻau lapaʻau i kahi papa o nā lāʻau i kapa ʻia he angiogenesis inhibitors, ʻo ia hoʻi ke kāohi nei i nā ʻōpū mai ka hana ʻana i nā kīʻaha koko hou. E noʻonoʻo iā ia e like me ka ʻoki ʻana i nā laina lako e hānai ana i nā cell maʻi ʻaʻai, e paʻakikī ai lākou e ola a hoʻonui i kou kino.

He aha ʻo Bevacizumab-awwb?

ʻO Bevacizumab-awwb he mana biosimilar o ka lāʻau lapaʻau bevacizumab mua. ʻO ka biosimilar he kope like loa ia o kahi lāʻau lapaʻau biological i ʻae mua ʻia e hana like me ka lāʻau mua.

ʻO ka lāʻau lapaʻau he monoclonal antibody, ʻo ia hoʻi ua hoʻolālā ʻia e kuhikuhi i hoʻokahi protein kikoʻī i kou kino. I kēia hihia, kuhikuhi ʻo ia i kahi protein i kapa ʻia ʻo VEGF (vascular endothelial growth factor) e hoʻohana ai nā cell maʻi ʻaʻai e kūkulu i nā kīʻaha koko hou.

E loaʻa iā ʻoe kēia lāʻau lapaʻau ma o ka intravenous (IV) infusion, ʻo ia hoʻi e hele pololei ana i loko o kou kahe koko ma o ka vein. ʻO ka ʻāpana

ʻO nā maʻi ʻaʻai ʻē aʻe e hiki ke mālama ʻia me kēia lāʻau lapaʻau, aia kekahi mau ʻano maʻi ʻaʻai o ka māmā, ka maʻi ʻaʻai o ka puʻupaʻa, a me ka maʻi ʻaʻai o ka ʻāʻī. Na kāu kauka oncologist e hoʻoholo inā kūpono kēia lapaʻau no kāu ʻano a me ke kahua o ka maʻi ʻaʻai.

I kekahi manawa hoʻohana nā kauka i ka bevacizumab-awwb no ka glioblastoma hou, he ʻano maʻi lolo ʻino. I kēia mau hihia, hiki ke kōkua i ka hoʻolohi ʻana i ka ulu ʻana o ka maʻi ʻaʻai ke pau ka hana ʻana o nā lapaʻau ʻē aʻe.

Pehea e hana ai ʻo Bevacizumab-awwb?

Hana ʻo Bevacizumab-awwb ma ka pale ʻana i kahi protein i kapa ʻia ʻo VEGF e hoʻohana ai nā pūnaewele maʻi ʻaʻai e ulu ai i nā kīʻaha koko hou. Ke hiki ʻole i nā pūnaewele maʻi ʻaʻai ke hana i kēia mau kīʻaha koko hou, paʻakikī lākou i ka loaʻa ʻana o ka oxygen a me nā meaʻai e pono ai lākou e ola a hoʻonui.

Ua manaʻo ʻia he lapaʻau i manaʻo ʻia ma mua o ka chemotherapy kuʻuna. Ma kahi o ka hoʻouka ʻana i nā pūnaewele e mahele wikiwiki ana, ua manaʻo ʻia i ka hana e kōkua ai i nā maʻi ʻaʻai e ulu i kā lākou lako koko.

ʻAʻole pepehi pololei ka lāʻau lapaʻau i nā pūnaewele maʻi ʻaʻai e like me kekahi mau lapaʻau ʻē aʻe. Ma kahi, hoʻonāwaliwali ia iā lākou ma ka ʻoki ʻana i ko lākou ola, e hoʻolilo iā lākou i mea nāwaliwali i nā lapaʻau maʻi ʻaʻai ʻē aʻe āu e loaʻa nei.

Hiki i kēia ala ke kōkua i ka hoʻolohi ʻana i ka ulu ʻana o ka maʻi ʻaʻai a hiki ke hoʻonui i ka maikaʻi o ka chemotherapy ke hoʻohana pū ʻia. Eia naʻe, ua manaʻo ʻia he lapaʻau kākoʻo ma mua o ka lāʻau lapaʻau ma kona iho.

Pehea e lawe ai au i ka Bevacizumab-awwb?

E loaʻa iā ʻoe ka bevacizumab-awwb ma ke ʻano he infusion intravenous ma kahi haukapila a i ʻole ke kikowaena lapaʻau maʻi ʻaʻai. Pono e hāʻawi ʻia ka lāʻau lapaʻau e nā poʻe loea mālama ola i hoʻomaʻamaʻa ʻia e hiki ke nānā iā ʻoe i ka wā o ka lapaʻau.

ʻO ka mea maʻamau, e lawe ana kāu infusion mua ma kahi o 90 mau minuke, e ʻae ana i kāu hui lapaʻau e nānā pono no nā hopena. Inā ʻoe e ʻae maikaʻi i ka mahele mua, hiki ke hāʻawi ʻia nā infusions e hiki mai ana ma luna o 60 mau minuke, a ma hope o 30 mau minuke.

Hāʻawi ʻia ka lāʻau lapaʻau i kēlā me kēia 2-3 pule, ma muli o kāu hoʻolālā lapaʻau kikoʻī a me nā lāʻau lapaʻau ʻē aʻe āu e loaʻa nei. E hoʻoholo kāu oncologist i ka papa manawa kūpono e pili ana i ke ʻano o kāu maʻi maʻi a me ke olakino holoʻokoʻa.

ʻAʻole pono ʻoe e hoʻokē ʻai a i ʻole e hahai i kekahi ʻano meaʻai kūikawā ma mua o kāu infusion. Eia naʻe, he mea nui e noho maikaʻi i ka wai a ʻai maʻamau ke ʻole e hāʻawi kāu kauka iā ʻoe i nā ʻōlelo kuhikuhi ʻē aʻe.

Pehea ka lōʻihi e lawe ai au i ka Bevacizumab-awwb?

ʻO ka lōʻihi o ka mālama ʻana me bevacizumab-awwb e ʻokoʻa loa ma muli o ke ʻano o kāu maʻi maʻi, pehea ka maikaʻi o kāu pane ʻana i ka mālama ʻana, a me ka maikaʻi o kou ʻae ʻana i ka lāʻau lapaʻau. Loaʻa i kekahi poʻe ia no kekahi mau mahina, a ʻo nā mea ʻē aʻe e pono paha ia no hoʻokahi makahiki.

E nānā mau kāu oncologist i kāu maʻi maʻi ma o nā scans a me nā hoʻokolohua koko e ʻike i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau. Inā e pane maikaʻi ana kāu maʻi maʻi a ʻaʻole ʻoe e ʻike i nā hopena ʻaoʻao koʻikoʻi, hiki ke hoʻomau ʻia ka mālama ʻana.

Hoʻopau maʻamau ka mālama ʻana inā holomua kāu maʻi maʻi me ka nānā ʻole i ka lāʻau lapaʻau, inā e hoʻomohala ʻoe i nā hopena ʻaoʻao koʻikoʻi, a i ʻole inā hoʻoholo kāu kauka i ka nui o nā pilikia ma mua o nā pōmaikaʻi. I kekahi manawa hiki ke hoʻomaha ʻia ka mālama ʻana no ka manawa pōkole inā pono ʻoe i ke ʻoki a i ʻole e hoʻomohala i kekahi mau pilikia.

ʻO ka hoʻoholo e hoʻomau a hoʻōki paha i ka mālama ʻana e hana mau ʻia ma waena ou a me kāu hui oncology, e noʻonoʻo ana i kou olakino holoʻokoʻa, ka maikaʻi o ke ola, a me nā pahuhopu lapaʻau.

He aha nā hopena ʻaoʻao o Bevacizumab-awwb?

Hiki i ka Bevacizumab-awwb ke hoʻoulu i nā hopena ʻaoʻao like ʻole, mai ka maʻalahi a i ka koʻikoʻi. ʻIke ka hapa nui o nā kānaka i kekahi mau hopena ʻaoʻao, akā hiki ke mālama ʻia ka nui me ka mālama olakino kūpono a me ka nānā ʻana.

Eia nā hopena ʻaoʻao maʻamau āu e ʻike ai i ka wā o ka mālama ʻana:

• Ke koko kiʻekiʻe, e nānā pono kāu kauka
• Luhi a me ka nāwaliwali e pili ana i kāu hana i kēlā lā i kēia lā
• Hoʻēmi ʻia ka ʻai a me ka lilo ʻana o ke kaumaha
• Pāpaʻa a i ʻole nā loli i ka neʻe ʻana o ka ʻōpū
• Nausea a me ka luaʻi ʻana i kekahi manawa
• Kahe koko i ka ihu a i ʻole ke kahe koko ʻana o nā ʻāʻī
• Nā ʻeha poʻo e hiki mai ana a hele
• Nā loli i ka ʻono a i ʻole nā ʻeha waha

Hiki ke mālama ʻia kēia mau hopena ʻaoʻao maʻamau, a hiki i kāu hui mālama ola ke hāʻawi i nā lāʻau lapaʻau a i ʻole nā hoʻolālā e kōkua iā ʻoe e ʻoluʻolu.

Aia kekahi mau hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau e koi ana i ka lāʻau lapaʻau koke. ʻOiai ʻaʻole e hiki mai kēia mau mea i nā mea a pau, he mea nui e ʻike iā lākou:

• Ke kahe koko nui, me ke kahe koko i loko
• Nā koko koko i nā wāwae, nā māmā, a i ʻole nā ʻōkana ʻē aʻe
• Nā pilikia o ka puʻupaʻa a i ʻole nā loli i ka mimi
• Ke koko kiʻekiʻe nui ʻaʻole e pane i ka lāʻau lapaʻau
• Ka lua o ka ʻōpū (he lua i loko o ka ʻōpū)
• Hoʻōla ʻeha lohi a i ʻole nā pilikia ʻeha
• Nā pilikia o ka naʻau a i ʻole ka puʻuwai
• ʻO ka hahau ʻana a i ʻole nā pilikia neurological ʻē aʻe

E nānā pono kāu hui lapaʻau iā ʻoe no kēia mau hopena ʻaoʻao koʻikoʻi a e aʻo iā ʻoe i nā hōʻailona ʻōlelo aʻo e nānā ai ma ka home.

ʻO kekahi mau hopena ʻaoʻao laha akā koʻikoʻi e pili ana i ka maʻi leukoencephalopathy posterior reversible (RPLS), e pili ana i ka lolo, a me nā hopena maʻi maʻi koʻikoʻi i ka wā o ka hoʻokomo ʻana. ʻAʻole maʻamau kēia mau mea akā pono ka lāʻau lapaʻau koke inā loaʻa.

ʻO wai ka mea ʻaʻole pono e lawe iā Bevacizumab-awwb?

ʻAʻole kūpono ʻo Bevacizumab-awwb no nā mea a pau, a e loiloi pono kāu kauka inā palekana ia iā ʻoe. ʻO kekahi mau maʻi olakino a i ʻole nā kūlana e hoʻoweliweli loa ai kēia lāʻau lapaʻau.

ʻAʻole pono ʻoe e loaʻa i kēia lāʻau lapaʻau inā hāpai ʻoe a i ʻole e hānai ana i ka waiū, no ka mea, hiki iā ia ke hōʻeha i kāu pēpē e ulu ana. Pono nā wāhine o ka makahiki hānau ke hoʻohana i ka mana hānau kūpono i ka wā o ka mālama ʻana a no kekahi mau mahina ma hope o ka lāʻau hope loa.

ʻAʻole paha e kūpono nā kānaka me ka ʻoki hou a i ʻole e hiki mai ana i kēia lapaʻau. Hiki i ka lāʻau lapaʻau ke hoʻopilikia i ka hoʻōla ʻana i ka ʻeha, no laila e kali maʻamau kāu kauka a hiki i ka wā e ola piha ai ʻoe mai ke ʻoki ʻana ma mua o ka hoʻomaka ʻana i ka lapaʻau.

Eia nā kūlana ʻē aʻe e pale ai iā ʻoe mai ka loaʻa ʻana o bevacizumab-awwb:

• Ke koko kiʻekiʻe ʻole i ka mana
• Hoʻouka naʻau hou a i ʻole ka hahau
• Ke kahe koko ikaika a i ʻole nā maʻi kahe koko
• Maʻi ate a i ʻole maʻi kīkī koʻikoʻi
• Mōʻaukala o ka perforation ʻōpū
• Nā ʻano maʻi lolo me ka pilikia kahe koko kiʻekiʻe
• Nā hopena maʻi i ka bevacizumab a i ʻole nā lāʻau lapaʻau like

E nānā kāu oncologist i kāu mōʻaukala olakino piha a me ke kūlana olakino o kēia manawa e hoʻoholo ai inā kūpono kēia lapaʻau iā ʻoe.

Nā inoa inoa o Bevacizumab-awwb

Loaʻa ʻo Bevacizumab-awwb ma lalo o ka inoa inoa Mvasi. Ua hoʻomohala ʻia kēia biosimilar e hāʻawi i kahi koho ʻoi aku ka maikaʻi ke hoʻohālikelike ʻia me ka lāʻau bevacizumab mua.

Kūʻai ʻia ka bevacizumab mua ma lalo o ka inoa inoa Avastin. Hana nā lāʻau lapaʻau ʻelua ma ke ʻano like a loaʻa nā ʻano like a me ka palekana.

Hiki i kāu ʻinikua a i ʻole ke kikowaena lapaʻau ke hoʻoholo i ka mana āu e loaʻa ai. Ua manaʻo ʻia nā mea ʻelua he kūpono like no ka mālama ʻana i ka maʻi kanesa, no laila hiki iā ʻoe ke hilinaʻi i kekahi koho a kāu kauka e kuhikuhi ai.

Nā koho ʻē aʻe o Bevacizumab-awwb

Nui nā lapaʻau ʻē aʻe no nā maʻi kanesa e mālama ai ʻo bevacizumab-awwb. E noʻonoʻo kāu oncologist i kēia mau koho ma muli o kāu ʻano maʻi kanesa, ke kahua, a me ke olakino holoʻokoʻa.

ʻO nā mea pale angiogenesis ʻē aʻe e komo pū ana me ramucirumab a me aflibercept, e hana like ana ma ka pale ʻana i ka ulu ʻana o nā kīʻaha koko i nā maʻi ʻaʻai. He mau koho paha kēia mau lāʻau lapaʻau inā ʻaʻole kūpono ʻo bevacizumab-awwb iā ʻoe a i ʻole e pau ka hana.

Hiki i nā lāʻau lapaʻau i manaʻo ʻia e like me cetuximab a i ʻole panitumumab ke lilo i mau koho ʻē aʻe no kekahi mau ʻano maʻi ʻaʻai colorectal, ʻoiai inā he mau ʻano genetic kikoʻī ko kāu maʻi ʻaʻai. Hana ʻokoʻa kēia mau mea ma ka manaʻo ʻana i nā protein ma nā ʻili o nā cell maʻi ʻaʻai.

He mea nui nā regimens chemotherapy kuʻuna a he mea maʻamau ka hoʻohana ʻana i ka hui pū ʻana me a i ʻole ma kahi o bevacizumab-awwb. E kōkua kāu oncologist e hoʻoholo i ke ala lapaʻau maikaʻi loa no kou kūlana.

Ua ʻoi aku ka maikaʻi o Bevacizumab-awwb ma mua o Avastin?

He like loa ʻo Bevacizumab-awwb (Mvasi) a me Avastin i nā lāʻau lapaʻau me ka pono a me ka palekana like. ʻO ka ʻokoʻa nui ʻo bevacizumab-awwb he biosimilar, ʻo ia ka mea maʻamau e emi ke kumukūʻai ma mua o ka lāʻau lapaʻau kumu.

Ua hōʻike nā haʻawina lapaʻau e hana maikaʻi nā lāʻau lapaʻau biosimilar e like me bevacizumab-awwb e like me kā lākou mau hoa kumu. Pono ka FDA i nā biosimilars e hoʻokō i nā kūlana koʻikoʻi e hōʻoia ana he like loa lākou me ka lāʻau kumu.

Hiki i kāu kauka ke koho i kekahi ma luna o kekahi ma muli o nā mea e like me ke kumukūʻai, ka uhi ʻinikua, a i ʻole ka loaʻa ʻana ma kāu kikowaena lapaʻau. E hāʻawi nā lāʻau lapaʻau ʻelua iā ʻoe i nā pōmaikaʻi e hakakā ana i ka maʻi ʻaʻai.

ʻO ka koho ma waena o lākou e pili pinepine ana i nā mea e pili ana i ka hana ma mua o nā mea lapaʻau, no ka mea, ua manaʻo ʻia lāua he mea pono a palekana no ka mālama ʻana i ka maʻi ʻaʻai.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Bevacizumab-awwb

He palekana ʻo Bevacizumab-awwb no ka poʻe me ka maʻi puʻuwai?

Pono ka poʻe me ka maʻi puʻuwai i ka noʻonoʻo kūikawā ma mua o ka hoʻomaka ʻana i ka bevacizumab-awwb. Hiki i ka lāʻau lapaʻau ke hoʻonui i ke koko a hoʻonui paha i nā pilikia o ka puʻuwai, no laila e hana pū kāu oncologist me kāu cardiologist e hoʻoholo inā palekana ia no ʻoe.

Inā he moʻolelo kou o ka maʻi puʻuwai, ka puʻuwai i hala koke aku nei, a i ʻole ka maʻi puʻuwai koʻikoʻi, hiki i kāu kauka ke koho i nā lāʻau lapaʻau ʻē aʻe. Eia naʻe, hiki nō i ka poʻe me nā maʻi puʻuwai maʻalahi ke loaʻa i ka lāʻau lapaʻau me ka nānā pono.

E nānā paha kāu hui lapaʻau i ka hana o kou puʻuwai i ka wā o ka mālama ʻana, me ka nānā mau ʻana i ke koko a me nā hoʻokolohua hana puʻuwai. Hiki iā lākou ke hoʻoponopono i kāu mau lāʻau lapaʻau puʻuwai a i ʻole ka mahele bevacizumab-awwb inā pono.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o ka Bevacizumab-awwb?

No ka mea, hāʻawi ʻia ka bevacizumab-awwb e nā poʻe loea olakino i kahi hoʻonohonoho olakino, he mea maʻamau loa ka nui o ka lāʻau. Hoʻohālikelike ʻia ka lāʻau lapaʻau e pili ana i kou kaumaha a me ke kūlana olakino, a nānā nā limahana i aʻo ʻia i ke kaʻina hana infusion holoʻokoʻa.

Inā hopohopo ʻoe e pili ana i kāu mahele a i ʻole ʻike i nā hōʻailona maʻamau i ka wā a ma hope paha o kāu infusion, e haʻi koke i kāu hui mālama ola. Hiki iā lākou ke loiloi i kou kūlana a hāʻawi i ka mālama kūpono inā pono.

Ua aʻo ʻia nā limahana lapaʻau e lawelawe i nā pilikia e kū mai ana. Loaʻa iā lākou nā protocols e mālama ai i nā hopena maikaʻi ʻole a i ʻole nā hopohopo dosing e hiki ke hana.

He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Bevacizumab-awwb?

Inā hala ʻoe i kahi manawa i hoʻonohonoho ʻia no kāu infusion bevacizumab-awwb, e hoʻokaʻaʻike i kāu hui oncology i ka hiki wawe e hoʻonohonoho hou. E hana pū lākou me ʻoe e hoʻi i ke ala me kāu papa hana lapaʻau.

ʻAʻole pilikia ka nalo ʻana i hoʻokahi mahele lāʻau, akā he mea nui e mālama i kāu papa hana lapaʻau no nā hopena maikaʻi loa e hakakā ai i ka maʻi maʻi. Hiki i kāu kauka ke hoʻoponopono i ka manawa o kāu hālāwai aʻe ma muli o ka nui o ka manawa i hala.

Mai hoʻāʻo e hoʻoponopono i kahi mahele lāʻau i hala ma ka loaʻa ʻana o ka lāʻau hou. E hoʻoholo kāu hui oncology i ke ala maikaʻi loa e hoʻomau ai i kāu hoʻolālā lapaʻau me ka palekana a me ka maikaʻi.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Bevacizumab-awwb?

Pono e hana mau ʻia ka hoʻoholo e hooki i ka bevacizumab-awwb me kāu oncologist. Hoʻomau maʻamau ka lapaʻau inā e pane maikaʻi ana kāu maʻi maʻi a ʻaʻole ʻoe e ʻike i nā hopena ʻaoʻao koʻikoʻi.

E loiloi mau kāu kauka i kāu lapaʻau ma o nā scans, nā hoʻokolohua koko, a me nā hoʻokolohua kino. Inā holomua kāu maʻi maʻi me ka lapaʻau ʻana, a i ʻole inā lilo nā hopena ʻaoʻao i mea koʻikoʻi, hiki iā lākou ke ʻōlelo e hooki i ka lāʻau.

Pono paha kekahi poʻe e hooki no ka manawa pōkole no ke ʻoki ʻana a i ʻole e mālama i nā hopena ʻaoʻao, a laila hoʻomau i ka lapaʻau ma hope. Hiki i nā mea ʻē aʻe ke hoʻopau i kahi papa hana lapaʻau i hoʻolālā ʻia a laila hoʻololi i ka nānā ʻana a i ʻole nā ​​lapaʻau like ʻole.

Hiki iaʻu ke lawe i nā huaora a i ʻole nā ​​mea hoʻohui i ka wā e lawe ana iā Bevacizumab-awwb?

Pono ʻoe e kūkākūkā i nā huaora a i ʻole nā ​​mea hoʻohui me kāu hui oncology ma mua o ka lawe ʻana iā lākou i ka wā o ka lapaʻau bevacizumab-awwb. Hiki i kekahi mau mea hoʻohui ke launa pū me kāu lapaʻau maʻi maʻi a i ʻole e pili i ka maikaʻi o kāna hana.

ʻAʻole palekana paha kekahi mau mea hoʻohui, ʻo ia hoʻi nā mea e pili ana i ka hoʻopaʻa ʻana i ke koko a i ʻole ke koko, e lawe me bevacizumab-awwb. Hiki i kāu kauka ke aʻo iā ʻoe i nā mea hoʻohui palekana a pono no kou kūlana.

He nui ka poʻe i ʻike he mea kōkua ka multivitamin maʻamau i ka wā o ka lapaʻau maʻi maʻi, akā ʻoi aku ka maikaʻi o ka loaʻa ʻana o ka ʻae ʻana o kāu kauka. Hiki iā lākou ke ʻōlelo i nā mea hoʻohui kikoʻī e kōkua i ke kākoʻo ʻana i kou olakino i ka wā o ka lapaʻau.