He aha ʻo Cabotegravir a me Rilpivirine: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Cabotegravir a me rilpivirine he hui pū ʻana o nā lāʻau lapaʻau HIV i hāʻawi ʻia ma ke ʻano he injection i kēlā me kēia mahina a i ʻole i kēlā me kēia mahina ʻē aʻe. Hōʻike kēia lapaʻau i kahi holomua nui no ka poʻe e noho nei me ka HIV e makemake ana i ke kūʻokoʻa mai nā pila i kēlā me kēia lā me ka mālama ʻana i ka mana maikaʻi o kā lākou maʻi.

Hoʻohui ka injection i ʻelua mau lāʻau lapaʻau HIV ikaika i hoʻokahi pana āu e loaʻa ai ma ke keʻena o kāu mea mālama ola. Nui ka poʻe i ʻike i kēia ala he mea maʻalahi loa ma mua o ka hoʻomanaʻo ʻana i nā lāʻau lapaʻau i kēlā me kēia lā, a hiki ke hāʻawi i ka hoʻopaʻa ʻana i ka maʻi maikaʻi e like me nā lāʻau lapaʻau maʻamau i hoʻokumu ʻia i ka pila.

He aha ʻo Cabotegravir a me Rilpivirine?

ʻO Cabotegravir a me rilpivirine he hui pū ʻana o nā lāʻau lapaʻau injectable lōʻihi o ʻelua mau lāʻau lapaʻau HIV e hana pū ana e kāohi i ka maʻi. No ka papa o nā mea pale integrase ʻo Cabotegravir, ʻoiai ʻo rilpivirine he mea pale transcriptase reverse non-nucleoside.

Hele mai kēia lāʻau lapaʻau ma ke ʻano he ʻelua mau injections kaʻawale i hāʻawi ʻia i loko o nā ʻiʻo o kou ʻūhā i ka wā o ka kipa like. Noho ka lāʻau lapaʻau i loko o kou ʻōnaehana no nā pule, e hoʻokuʻu mālie ana i nā mea hana e mālama i kāu HIV ma lalo o ka mana me ka ʻole o nā pila i kēlā me kēia lā.

E hoʻomaka maʻamau kāu kauka iā ʻoe ma nā mana waha o kēia mau lāʻau lapaʻau like no hoʻokahi mahina. Kōkua kēia i ka hōʻoia ʻana e ʻae maikaʻi kou kino i nā lāʻau lapaʻau ma mua o ka hoʻololi ʻana i nā injections lōʻihi.

No ke aha e hoʻohana ʻia ai ʻo Cabotegravir a me Rilpivirine?

Hoʻomaʻamaʻa kēia hui pū ʻana i ka maʻi HIV-1 i nā pākeke i loaʻa mua i ka ukana viral hiki ʻole ke ʻike ʻia. Pono ʻoe e hoʻokō i ka hoʻopaʻa ʻana i ka maʻi me nā lāʻau lapaʻau HIV ʻē aʻe ma mua o ka hoʻololi ʻana i kēia mau injections.

Hana maikaʻi ka lapaʻau no ka poʻe i loaʻa ʻole ka hāʻule ʻana o ka lapaʻau me nā mea pale integrase a i ʻole nā lāʻau lapaʻau ʻano rilpivirine. E nānā kāu kauka i kāu mōʻaukala lapaʻau e hōʻoia i ka kūpono o kēia koho no kāu kūlana.

He nui ka poʻe e koho i kēia lapaʻau no ka mea e kāpae ana ia i ka pono o nā pila i kēlā me kēia lā me ka mālama ʻana i ka mana HIV maikaʻi loa. He mea kōkua nui ia inā pilikia ʻoe me ka ukana pila, pilikia i ka hoʻomanaʻo ʻana i nā lāʻau lapaʻau i kēlā me kēia lā, a i ʻole makemake wale i nā mea hoʻomanaʻo olakino liʻiliʻi i kou ola i kēlā me kēia lā.

Pehea e Hana ai ʻo Cabotegravir a me Rilpivirine?

Hana kēia hui pū ʻana i ka lāʻau lapaʻau ma ka pale ʻana i ka HIV ma nā pae ʻelua like ʻole o kāna pōʻai hana hou. Kāohi ʻo Cabotegravir i ka maʻi mai ka hoʻohui ʻana i kāna mea genetic i loko o kāu mau keena olakino, a ʻo rilpivirine e kāohi i ka maʻi mai ka hana ʻana i nā kope o ia iho.

Ua manaʻo ʻia nā lāʻau lapaʻau ʻelua he mau lāʻau lapaʻau HIV ikaika e hāʻawi ana i ka hoʻopaʻa ʻana i ka maʻi ikaika. ʻO ke ʻano hana lōʻihi e manaʻo ai e noho ana nā lāʻau lapaʻau i loko o kāu ʻōnaehana no nā pule ma hope o kēlā me kēia injection, e mālama ana i nā pae kūlike e mālama i ka maʻi.

ʻO ke ala pālua e paʻakikī loa ai ka HIV i ka hoʻomohala ʻana i ke kūʻē ʻana, no ka mea, pono ka maʻi e lanakila i ʻelua mau ʻano hana pale i ka manawa like. ʻO kēia ka mea e pono ai ka hui pū ʻana a me ka lōʻihi no ka mālama ʻana i ka HIV i ka wā lōʻihi.

Pehea e Lawe ai au iā Cabotegravir a me Rilpivirine?

E loaʻa iā ʻoe kēia mau injections ma ke keʻena o kāu mea mālama ola, ʻaʻole ma ka home. Aia i loko o ka lapaʻau ʻelua mau pana kaʻawale i hāʻawi ʻia i loko o kou mau ʻiʻo ʻūhā i ka manawa like.

Ma mua o ka hoʻomaka ʻana i nā injections, e lawe maʻamau ʻoe i nā mana waha o nā lāʻau lapaʻau ʻelua no kahi o ʻehā pule. Kōkua kēia manawa alakaʻi waha i kāu kauka e hōʻoia e ʻae maikaʻi ʻoe i nā lāʻau lapaʻau a loaʻa nā pae koko maikaʻi ma mua o ka hoʻololi ʻana i ke ʻano hana lōʻihi.

I ka wā o kāu kipa injection, e loaʻa iā ʻoe hoʻokahi pana o cabotegravir a me hoʻokahi pana o rilpivirine ma nā wahi like ʻole o kou ʻūhā. He mau minuke wale nō ke kaʻina hana injection, akā pono paha ʻoe e noho no kahi manawa nānā pōkole ma hope.

ʻAʻole pono ka hoʻomākaukau kūikawā ma mua o kāu manawa e loaʻa ai ka injection. Hiki iā ʻoe ke ʻai maʻamau a ʻaʻole pono e lawe i nā pila i nā lā injection ma hope o kou hoʻopau ʻana i ka manawa alakaʻi waha.

Pehea ka lōʻihi e lawe ai au i ka Cabotegravir a me Rilpivirine?

E hoʻomau ʻoe i kēia mau injections no ka lōʻihi e kāohi pono ana lākou i kāu HIV a ke ʻae maikaʻi nei ʻoe iā lākou. Noho ka hapa nui o nā kānaka i kēia lapaʻau no ka wā lōʻihi, e like me nā lāʻau lapaʻau HIV ʻē aʻe.

E nānā kāu kauka i kāu ukana viral i nā manawa a pau e hōʻoia i ka hana pono ʻana o ka lapaʻau. ʻOiai e noho ana kāu maʻi i ka ʻike ʻole ʻia a ʻaʻole ʻoe e ʻike i nā hopena ʻaoʻao pilikia, hiki iā ʻoe ke hoʻomau i nā injections no ka manawa pau ʻole.

Inā hoʻoholo ʻoe e hooki i nā injections no kekahi kumu, e kōkua kāu kauka iā ʻoe e hoʻololi i nā lāʻau lapaʻau HIV waha i kēlā me kēia lā. Pono e hoʻolālā pono ʻia kēia hoʻololi ʻana e pale aku i nā āpau i kāu lapaʻau HIV e hiki ai i ka maʻi ke hoʻi hou.

He aha nā hopena ʻaoʻao o Cabotegravir a me Rilpivirine?

ʻAe ka hapa nui o nā kānaka i kēia mau injections, akā hiki iā ʻoe ke ʻike i kekahi mau hopena ʻaoʻao, ʻoi aku hoʻi i nā mahina mua. Pili ka hapa nui o nā pilikia i ka wahi injection a me kekahi mau hōʻailona kino maʻamau.

Eia nā hopena ʻaoʻao e ʻike nui ai ʻoe i ka wā e hoʻoponopono ai kou kino i kēia lapaʻau:

• ʻEha, pehu, a i ʻole ke aloha ma nā wahi injection
• ʻEhaʻeha a me ka luhi
• ʻEhaʻeha ʻiʻo a me ka ʻeha hui
• Nausea a i ʻole ka ʻoluʻolu o ka ʻōpū
• Pōpō a i ʻole pilikia i ka hiamoe
• Fiva a i ʻole nā ​​hōʻailona e like me ka maʻi flu

Hoʻomaikaʻi nui kēia mau hopena ʻaoʻao maʻamau ma hope o nā pōʻai injection mua e like me ka hoʻoponopono ʻana o kou kino i ka hana maʻamau o ka lāʻau.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao nui e pono ai ka lāʻau lapaʻau. ʻOiai ʻaʻole maʻamau kēia mau mea, he mea nui e ʻike i ka mea e nānā ai i hiki iā ʻoe ke loaʻa ke kōkua inā pono.

E kāhea aku i kāu mea mālama ola inā loaʻa iā ʻoe kekahi o kēia mau pilikia koʻikoʻi:

• Nā hopena koʻikoʻi ma ke kahua o ka pahu me ka pehu nui, paʻakikī, a i ʻole nā hōʻailona maʻi
• Nā loli mau i ke ʻano, ke kaumaha, a i ʻole nā manaʻo e pepehi iā ʻoe iho
• Nā hopena ʻili koʻikoʻi a i ʻole nā ʻōpala
• Nā hōʻailona o nā pilikia o ke ake e like me ka melemele o ka ʻili a i ʻole nā maka
• Nāwaliwali ʻiʻo ʻokoʻa a i ʻole ka ʻeha
• Nā hopena maʻi maʻi koʻikoʻi me ka pilikia o ka hanu

ʻOiai he mea maʻamau ʻole, hiki i kekahi poʻe ke hoʻomohala i nā hopena ma hope o ka pahu e hiki ke hana i loko o kekahi mau minuke a i ʻole mau hola ma hope o ka loaʻa ʻana o nā pahu. ʻAʻole maʻamau kēia mau hopena akā pono ka lāʻau lapaʻau koke inā pili lākou i ka pilikia o ka hanu a i ʻole nā hōʻailona koʻikoʻi o ke kino holoʻokoʻa.

ʻO wai ka mea pono ʻole e lawe iā Cabotegravir a me Rilpivirine?

ʻAʻole kūpono kēia hui pū ʻana o ka pahu no nā mea a pau me ka HIV. E nānā pono kāu kauka i kāu mōʻaukala olakino a me ke kūlana olakino o kēia manawa e hoʻoholo ai inā palekana kēia lapaʻau iā ʻoe.

ʻAʻole pono ʻoe e loaʻa i kēia mau pahu inā loaʻa iā ʻoe kekahi mau maʻi olakino a i ʻole e lawe i nā lāʻau lapaʻau kikoʻī e hiki ke launa pū me ka lāʻau lapaʻau.

Eia nā kūlana nui kahi i ʻōlelo ʻole ʻia ai kēia lapaʻau:

• Nā hopena maʻi ma mua i ka cabotegravir a i ʻole rilpivirine
• Maʻi hepatitis B i kēia manawa (pono ka noʻonoʻo kūikawā)
• Ke lawe nei i kekahi mau lāʻau lapaʻau e launa nui me kēia mau lāʻau
• Mōʻaukala o ka hāʻule ʻana o ka lāʻau lapaʻau me nā mea pale integrase a i ʻole nā lāʻau ʻano rilpivirine
• Maʻi ate koʻikoʻi a i ʻole nā enzyme ate i hoʻokiʻekiʻe nui ʻia
• Hāpai a i ʻole e hoʻolālā ana e hāpai

E noʻonoʻo pū kāu kauka inā e lawe ana ʻoe i nā lāʻau lapaʻau ʻē aʻe e hiki ke hoʻopilikia i kēia mau pahu, me kekahi mau antacids, nā lāʻau lapaʻau hopu, a i ʻole kekahi mau antibiotics.

ʻO kekahi poʻe me nā pilikia o ka puʻupaʻa, nā maʻi noʻonoʻo, a i ʻole nā pilikia olakino ʻē aʻe e pono paha i ka nānā ʻana a i ʻole nā ʻano lapaʻau like ʻole. E hana pū kāu hui mālama ola me ʻoe e hoʻoholo i ka hoʻolālā lapaʻau HIV palekana a maikaʻi loa no kāu kūlana.

Nā inoa inoa o Cabotegravir a me Rilpivirine

ʻO ka inoa inoa no kēia hui injectable ʻo Cabenuva. ʻO kēia wale nō ka formulation i loaʻa i kēia manawa e hui pū ana i nā lāʻau ʻelua i loko o kahi ʻōnaehana injection lōʻihi.

Hana ʻia ʻo Cabenuva e ViiV Healthcare a ua hoʻolālā kūikawā ʻia ma ke ʻano he koho injection i kēlā me kēia mahina a i ʻole i kēlā me kēia mahina ʻē aʻe i nā pila HIV i kēlā me kēia lā. ʻO ka inoa inoa ka mea like inā loaʻa iā ʻoe ka mahele i kēlā me kēia mahina a i ʻole i kēlā me kēia mahina ʻē aʻe.

Hiki i kāu hale kūʻai lāʻau a me ka ʻinikua ke kuhikuhi i kēia lāʻau ma kona inoa inoa (Cabenuva) a i ʻole ma nā inoa lāʻau pākahi (cabotegravir a me rilpivirine extended-release injectable suspension).

Nā koho ʻē aʻe o Cabotegravir a me Rilpivirine

Loaʻa nā koho lapaʻau HIV ʻē aʻe inā ʻaʻole kūpono ka therapy injectable iā ʻoe. Hiki i kāu kauka ke kōkua iā ʻoe e koho i ke koho maikaʻi loa e pili ana i kāu mau pono, ka mōʻaukala olakino, a me nā makemake.

ʻO nā lāʻau lapaʻau HIV waha i kēlā me kēia lā ka mea maʻamau i ka lapaʻau a hana maikaʻi loa no ka hapa nui o nā kānaka. Hiki i kēia mau mea ke komo i nā hui e like me bictegravir/tenofovir alafenamide/emtricitabine a i ʻole dolutegravir me nā lāʻau ʻē aʻe.

Ke hoʻomohala ʻia nei nā koho lōʻihi ʻē aʻe, me nā hui injectable like ʻole a me nā formulations lōʻihi. Hiki i kāu mea mālama ola ke kūkākūkā i nā lapaʻau e loaʻa ana i ka wā e hiki mai ana inā ʻaʻole kūpono nā koho i kēia manawa i kāu mau pono.

Pono kekahi poʻe mai ka hoʻololi ʻana ma waena o nā ʻano lapaʻau HIV like ʻole i ka wā e loli ai ko lākou ola. ʻO ka mea nui ka mālama ʻana i ka hoʻopaʻa ʻana i ka maʻi maʻi maʻi maʻi maikaʻi me nā lapaʻau e hana maikaʻi loa no kāu kūlana.

Ua ʻoi aku ka maikaʻi o Cabotegravir a me Rilpivirine ma mua o nā lāʻau lapaʻau HIV ʻē aʻe?

ʻAʻole pono kēia hui pū ʻana i ka injectable i

E kāhea koke i kāu mea mālama ola inā ua hala a i ʻole e hala ana ʻoe i kāu manawa hoʻopaʻa ʻia no ka hoʻokomo ʻana. He mea nui ka manawa o kēia mau hoʻokomo ʻana e mālama i nā pae lāʻau kūpono i loko o kou kino.

Ma muli o ka lōʻihi o kou hala ʻana, hiki i kāu kauka ke ʻōlelo aku e lawe i nā lāʻau HIV waha no ka manawa e hoʻopihapiha i ka hakahaka a hiki i kou loaʻa ʻana o kāu hoʻokomo ʻana. Pale kēia i kekahi hōʻoki ʻana i kāu lapaʻau HIV.

E hoʻonohonoho hou kāu hui mālama ola i kāu hoʻokomo ʻana i ka wā hiki loa a hiki ke hoʻololi i kāu papa hoʻokomo e hiki mai ana. Mai hoʻāʻo e hoʻoponopono i nā hoʻokomo i hala ma ka lawe ʻana i nā lāʻau hou aʻe a i ʻole ka hoʻololi ʻana i kāu papa manawa me ka ʻole o ke alakaʻi olakino.

Hiki iaʻu ke hooki koke i ka lawe ʻana iā Cabotegravir a me Rilpivirine?

ʻAʻole pono ʻoe e hooki koke i kēia mau hoʻokomo ʻana me ka ʻole o ka mālama olakino. Noho nā lāʻau lapaʻau i loko o kou kino no nā pule ma hope o kāu hoʻokomo hope loa, akā hiki i ka hooki koke ʻana ke alakaʻi i ka hāʻule ʻana o ka lapaʻau a me ka hoʻomohala ʻana i ke kūpaʻa.

Inā makemake ʻoe e hooki i nā hoʻokomo ʻana, e kōkua kāu kauka iā ʻoe e hoʻololi palekana i nā lāʻau HIV waha. Pono e hoʻonohonoho pono ʻia kēia hoʻololi ʻana e hōʻoia i ka hoʻomau ʻana o ka hoʻopaʻa ʻana i ka maʻi maʻi i ka wā o ka hoʻololi.

ʻO ke ʻano lōʻihi o kēia mau hoʻokomo ʻana, ʻo ia hoʻi, pono ʻoe i ke alakaʻi olakino e hooki palekana. E hana kāu mea mālama ola i kahi hoʻolālā e pale ai i kou olakino me ka mahalo i kāu makemake lapaʻau.

E pili anei kēia mau hoʻokomo ʻana i koʻu hiki ke loaʻa nā keiki?

ʻAʻole ʻōlelo ʻia kēia mau hoʻokomo ʻana i ka wā hāpai, a he palena ka ʻike e pili ana i kā lākou hopena i ka momona. Inā ʻoe e hoʻolālā ana e hāpai, e kūkākūkā i nā lapaʻau HIV ʻē aʻe me kāu kauka.

No nā kāne, ʻaʻohe hōʻike e pili ana kēia mau lāʻau lapaʻau i ka momona a i ʻole ka hana ʻana o ka sperm. Eia naʻe, ʻo ka mālama ʻana i nā ukana viral hiki ʻole ke ʻike ʻia me kekahi lapaʻau HIV kūpono he mea nui ia no ka hōʻemi ʻana i ka pilikia o ka hoʻouna ʻana i nā hoa.

Inā hāpai ʻoe i ka wā e loaʻa ana kēia mau injections, e kelepona koke i kāu mea mālama ola. E kōkua lākou iā ʻoe e hoʻololi i nā lāʻau HIV palekana no ka hāpai ʻana e pale aku iā ʻoe a me kāu pēpē e ulu nei.

Pehea ka lōʻihi o ka lōʻihi o nā hopena o ka wahi injection?

Hoʻomaikaʻi ka hapa nui o nā hopena o ka wahi injection i loko o kekahi mau lā a i hoʻokahi pule ma hope o kēlā me kēia injection. ʻO ka ʻeha, ka pehu, a me ke aloha i nā wahi injection he mea maʻamau, ʻoiai i kāu mau pōʻai injection mua.

Hiki iā ʻoe ke hoʻohana i nā mea hōʻoluʻolu ʻeha ma luna o ka pā a hoʻopili i ka hau a i ʻole ka wela i nā wahi injection e kōkua i ka mālama ʻana i ka ʻoluʻolu. Hiki i ka lomilomi mālie a me ka hana māmā ke kōkua i ka hōʻemi ʻana i ka ʻeha.

ʻO ka maʻamau, ʻaʻole ʻike ʻia nā hopena o ka wahi injection i ka wā e hoʻoponopono ai kou kino i ka hana lapaʻau. Inā ʻike ʻia nā hopena e ʻoi aku ka maikaʻi ʻole a ʻaʻole e hoʻomaikaʻi ma hope o hoʻokahi pule, e kelepona i kāu mea mālama ola no ka loiloi.