He aha ʻo Cabozantinib: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau maʻi ʻaʻai ʻo Cabozantinib e kōkua ana i ka hoʻolohi ʻana i ka ulu ʻana o kekahi mau ʻano o nā pūnaewele maʻi ʻaʻai. No ka papa o nā lāʻau i kapa ʻia ʻo tyrosine kinase inhibitors, e hana ana ma ka pale ʻana i nā protein kikoʻī e pono ai nā pūnaewele maʻi ʻaʻai e ulu a laha i kou kino.

He koho lapaʻau nui kēia lāʻau no ka poʻe e kū ana i ka maʻi ʻaʻai kīkī holomua, ka maʻi ʻaʻai ate, a me ka maʻi ʻaʻai thyroid. Hiki i kāu kauka ke ʻōlelo aku iā cabozantinib i ka wā i hana ʻole ai nā lāʻau lapaʻau ʻē aʻe a i ʻole i ka wā i loaʻa ai i kāu maʻi ʻaʻai nā ʻano kikoʻī e lilo ai kēia lāʻau i koho maikaʻi no kou kūlana.

No ke aha e hoʻohana ʻia ai ʻo Cabozantinib?

Hoʻomaʻamaʻa ʻo Cabozantinib i ʻekolu ʻano nui o ka maʻi ʻaʻai holomua. E hoʻoholo kāu oncologist inā kūpono kēia lāʻau lapaʻau no kāu kūlana kikoʻī e pili ana i kāu ʻano maʻi ʻaʻai, ke kahua, a me ke ʻano o kāu pane ʻana i nā lāʻau lapaʻau ʻē aʻe.

ʻO ka hoʻohana maʻamau no ka maʻi ʻaʻai kīkī holomua, i kapa ʻia hoʻi ʻo renal cell carcinoma. Hiki i kēia lāʻau lapaʻau ke kōkua i ka hoʻolohi ʻana i ka ulu ʻana o ke tumora i ka wā i laha ai ka maʻi ʻaʻai i nā ʻāpana ʻē aʻe o kou kino a i ʻole i ka wā i hiki ʻole ai ke ʻoki.

Hoʻonohonoho pū nā kauka iā cabozantinib no ka hepatocellular carcinoma, ʻo ia ke ʻano maʻamau o ka maʻi ʻaʻai ate. Hoʻohana maʻamau ʻia i ka wā i holomua ai ka maʻi ʻaʻai a ʻaʻole nā koho nā lāʻau lapaʻau ʻē aʻe e like me ke ʻoki a i ʻole ka transplant ate.

Eia kekahi, mālama kēia lāʻau lapaʻau i ka maʻi ʻaʻai thyroid i hoʻokaʻawale ʻia i laha a ʻaʻole pane i ka lāʻau iodine radioactive. E hoʻāʻo maʻamau kāu kauka i nā lāʻau lapaʻau maʻi ʻaʻai thyroid ʻē aʻe ma mua o ka noʻonoʻo ʻana iā cabozantinib.

Pehea e hana ai ʻo Cabozantinib?

Ua manaʻo ʻia ʻo Cabozantinib he lāʻau lapaʻau maʻi ʻaʻai ikaika, i manaʻo ʻia e pale ana i nā ala he nui e hoʻohana ai nā pūnaewele maʻi ʻaʻai e ola a ulu. ʻAʻole like me ka chemotherapy e pili ana i nā pūnaewele e mahele wikiwiki ana, ua manaʻo ʻia kēia lāʻau i nā protein e hilinaʻi ai nā pūnaewele maʻi ʻaʻai.

Hana ka lāʻau lapaʻau ma ka pale ʻana i nā tyrosine kinases, he mau enzyme e hoʻouna ana i nā hōʻailona ulu i nā pūnaewele maʻi ʻaʻai. Ke pale ʻia kēia mau hōʻailona, ʻaʻole hiki i nā pūnaewele maʻi ʻaʻai ke hoʻonui wikiwiki a hiki ke make.

Hoʻopā kēia lāʻau i nā kīʻaha koko e hānai ana i nā ʻōpū, e ʻoki ana i kā lākou oxygen a me ka lako meaʻai. Ma ka pale ʻana i kēia mau ala, hiki i ka cabozantinib ke kōkua i ka hoʻemi ʻana i nā ʻōpū a i ʻole ka lohi ʻana i ko lākou ulu ʻana, e hāʻawi ana iā ʻoe i ka manawa hou a me ka maikaʻi o ke ola.

ʻAʻole koke nā hopena no ka mea e hana ana kēia lāʻau lapaʻau i nā pule a i nā mahina. E nānā kāu kauka i kāu pane ma o nā scans maʻamau a me nā hoʻokolohua koko e ʻike ai i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau.

Pehea e lawe ai au i ka Cabozantinib?

E lawe i ka cabozantinib e like me ke kauoha a kāu kauka, maʻamau hoʻokahi manawa i ka lā i ka manawa like i kēlā me kēia lā. Hele mai ka lāʻau lapaʻau i loko o nā capsules e pono ai ʻoe e ale holoʻokoʻa me ke aniani wai piha.

Pono ʻoe e lawe i kēia lāʻau lapaʻau ma ka ʻōpū ʻole, ʻo ia hoʻi ma ka liʻiliʻi hoʻokahi hola ma mua o ka ʻai ʻana a i ʻole ʻelua hola ma hope o ka ʻai ʻana. Hiki i ka meaʻai ke hoʻopilikia i ka nui o ka lāʻau e komo ai kou kino, e hoʻemi ana i ka maikaʻi.

Inā pilikia ʻoe i ka ale ʻana i nā capsules, mai wehe a ʻokiʻoki paha iā lākou. Akā, e kamaʻilio me kāu kauka e pili ana i nā ala ʻē aʻe e lawe ai i ka lāʻau lapaʻau. Aia i loko o nā capsules kahi formulation kikoʻī e pono ai e noho paʻa.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi maʻamau maʻamau akā hiki ke hoʻoponopono iā ia ma muli o ke ʻano o kāu pane ʻana a me nā hopena ʻaoʻao āu e ʻike ai. Mai hoʻololi i kāu mahele a i ʻole e hooki i ka lawe ʻana i ka lāʻau lapaʻau me ka ʻole e kamaʻilio mua me kāu hui mālama ola.

Pehea ka lōʻihi e lawe ai au i ka Cabozantinib?

E lawe maʻamau ʻoe i ka cabozantinib no ka lōʻihi e kōkua ana i ka mālama ʻana i kāu maʻi ʻaʻai a ke ʻae nei ʻoe i nā hopena ʻaoʻao me ka maikaʻi. ʻO kēia ka manaʻo e lawe ana iā ia no nā mahina a i ʻole nā makahiki, no ka mea, ua hoʻolālā ʻia e lilo i lapaʻau lōʻihi.

E loiloi mau kāu kauka inā e hana ana ka lāʻau lapaʻau ma o nā scans, nā hoʻokolohua koko, a me ka nānā ʻana i kāu mau hōʻailona. Inā hoʻomaka hou kāu maʻi maʻi a i ʻole inā lilo nā hopena ʻaoʻao i mea paʻakikī loa e mālama ai, hiki i kāu kauka ke kūkākūkā i ka hoʻololi ʻana i kāu hoʻolālā lapaʻau.

Lawe kekahi poʻe i ka cabozantinib no nā mahina he nui me nā hopena maikaʻi, aʻo nā mea ʻē aʻe e pono e hooki koke ma muli o nā hopena ʻaoʻao a i ʻole inā ʻaʻole pane ka maʻi maʻi. He kū hoʻokahi kāu manawa lapaʻau i kāu kūlana a e nānā pono ʻia e kāu hui mālama ola.

Mai hooki koke i ka lawe ʻana i ka cabozantinib me ka ʻole o ke alakaʻi ʻana a kāu kauka, ʻoiai inā ʻoe e manaʻo maikaʻi ana. ʻO ka hooki ʻana i ka lāʻau lapaʻau hiki ke ʻae i kāu maʻi maʻi e ulu wikiwiki.

He aha nā hopena ʻaoʻao o Cabozantinib?

E like me nā lāʻau lapaʻau maʻi maʻi a pau, hiki i ka cabozantinib ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole i ʻike nā kānaka a pau iā lākou ma ke ala like. E kōkua kāu kauka iā ʻoe e mālama i kēia mau hopena i hiki iā ʻoe ke hoʻomau i ka lapaʻau me ka palekana.

Eia nā hopena ʻaoʻao maʻamau loa āu e ʻike ai:

• Luhi a me ka nāwaliwali e pili ana i kāu mau hana i kēlā me kēia lā
• Pāpaʻa, i kekahi manawa hiki ke koʻikoʻi
• Nausea a me ka emi ʻana o ka ʻai
• ʻO ka maʻi lima-wāwae, e hana ana i ka ʻeha, ka pehu, a me nā loli ʻili ma nā poho lima a me nā kapuaʻi
• Ke koko kiʻekiʻe e pono ai ka nānā ʻana
• Ka pohō kaumaha
• Nā loli kala lauoho a i ʻole ka lauoho lahilahi
• Nā ʻeha waha a i ʻole nā loli ʻono

E nānā pono kāu hui mālama ola iā ʻoe no kēia mau hopena a hiki ke hāʻawi i nā lāʻau lapaʻau a i ʻole nā ​​hoʻolālā e kōkua i ka mālama ʻana iā lākou. Nui nā hopena ʻaoʻao e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lapaʻau.

Pono nā hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau i ka lāʻau lapaʻau koke. Aia kēia mau mea i ke kahe koko nui, nā koko koko, nā pilikia o ka naʻau, a i ʻole nā ​​hōʻailona o ka pōʻino o ke ake e like me ka melemele ʻana o ka ʻili a i ʻole ka ʻeha o ka ʻōpū.

Hiki ke loaʻa kekahi mau pilikia maʻamau akā koʻikoʻi, e like me ke koko kiʻekiʻe loa, nā koko koko i loko o nā māmā a i ʻole nā wāwae, a me nā pilikia me ka hoʻōla ʻana i nā ʻeha. E nānā pono kāu kauka i kēia mau mea a pono paha e hoʻoponopono i kāu lapaʻau inā loaʻa lākou.

ʻO wai ka mea pono ʻole e lawe iā Cabozantinib?

ʻAʻole palekana ʻo Cabozantinib no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. Hiki i kekahi mau maʻi olakino a i ʻole nā lāʻau lapaʻau ke hana i kēia lāʻau i kūpono ʻole a i ʻole weliweli iā ʻoe.

ʻAʻole pono ʻoe e lawe iā cabozantinib inā hāpai ʻoe a i ʻole e hoʻolālā ana e hāpai, no ka mea, hiki iā ia ke hōʻeha i kahi pēpē e ulu ana. Pono nā wahine o ka makahiki hānau e hoʻohana i ka mana hānau kūpono i ka wā o ka lapaʻau a no kekahi mau mahina ma hope o ka hoʻōki ʻana i ka lāʻau.

ʻAʻole hiki i nā poʻe me nā pilikia ate koʻikoʻi ke lawe palekana i kēia lāʻau, no ka mea, hana ka ate i ka lāʻau. E nānā kāu kauka i kāu hana ate ma mua o ka hoʻomaka ʻana i ka lapaʻau a nānā mau.

Inā loaʻa iā ʻoe kahi ʻoki hou a i ʻole nā ʻeha i hoʻōla ʻole ʻia, hiki i kāu kauka ke hoʻopaneʻe i ka hoʻomaka ʻana i ka cabozantinib. Hiki i ka lāʻau ke keakea i ka hoʻōla ʻana i ka ʻeha a hoʻonui i ka pilikia o ke kahe ʻana.

ʻO nā kūlana ʻē aʻe e hiki ke hana i ka cabozantinib i kūpono ʻole me nā pilikia o ka naʻau koʻikoʻi, ke koko kiʻekiʻe ʻole, a i ʻole nā koko koko hou. E kaupaona kāu kauka i kēia mau pilikia e kūʻē i nā pōmaikaʻi hiki ke loaʻa o ka lapaʻau.

Nā inoa inoa inoa Cabozantinib

Loaʻa ʻo Cabozantinib ma lalo o ʻelua mau inoa inoa nui, kēlā me kēia me nā ʻano like ʻole no nā hoʻohana kikoʻī. E kauoha kāu kauka i ka mana i kūpono loa no kāu ʻano maʻi kanesa.

ʻO Cabometyx ka inoa inoa no nā papa cabozantinib i hoʻohana ʻia e mālama i ka maʻi kanesa o ka puʻupaʻa a me ka maʻi kanesa o ke ake. ʻO kēia ke ʻano i kauoha pinepine ʻia o ka lāʻau.

ʻO Cometriq ka inoa inoa no nā capsules cabozantinib i ʻae ʻia no kekahi mau ʻano maʻi kanesa thyroid. ʻOkoʻa iki ka dosing a me ka formulation mai Cabometyx.

Aia nā ʻano ʻelua i ka mea hana like, akā ua hana ʻia lākou ma nā ʻano like ʻole, no laila ʻaʻole pono ʻoe e hoʻololi ma waena o lākou me ka ʻole o ke alakaʻi ʻana a kāu kauka. E hāʻawi ka hale kūʻai lāʻau i ka mea āu i kauoha ai e kāu kauka.

Nā koho ʻē aʻe no Cabozantinib

Nui nā lāʻau lapaʻau ʻē aʻe i manaʻo ʻia e mālama i nā maʻi maʻi like ke kūpono ʻole ʻo cabozantinib a i ʻole ke pau ʻana o ka hana. E noʻonoʻo kāu oncologist i kēia mau koho ʻē aʻe e pili ana i kāu ʻano maʻi maʻi a me ke kūlana.

No ka maʻi maʻi kīkī, nā koho ʻē aʻe e komo pū ana me sunitinib, pazopanib, axitinib, a me nivolumab. Hana ʻokoʻa kēlā me kēia a ʻoi aku paha ka maikaʻi no nā pae like ʻole o ka maʻi a i ʻole nā mea maʻi pākahi.

ʻO nā koho ʻē aʻe no ka maʻi maʻi ate e komo pū ana me sorafenib, lenvatinib, a me regorafenib. Hiki i kāu kauka ke hoʻāʻo i kēia mau lāʻau ma mua a ma hope paha o cabozantinib e pili ana i nā ʻano o kāu maʻi maʻi.

No ka maʻi maʻi thyroid, nā koho ʻē aʻe e komo pū ana me sorafenib, lenvatinib, a me vandetanib. Aia ke koho i kāu ʻano maʻi maʻi thyroid a me ke ʻano o ka pane ʻana i nā lāʻau lapaʻau mua.

E noʻonoʻo kāu kauka i nā mea e like me kou olakino holoʻokoʻa, nā lāʻau lapaʻau mua, a me nā ʻano maʻi maʻi kikoʻī i ke koho ʻana i ke koho ʻē aʻe maikaʻi loa no kou kūlana.

ʻOi aku ka maikaʻi o Cabozantinib ma mua o Sunitinib?

He mau lāʻau lapaʻau maikaʻi ʻo Cabozantinib a me sunitinib no ka mālama ʻana i ka maʻi maʻi kīkī holomua, akā hana lākou ma nā ʻano like ʻole. E koho kāu kauka i ka mea e kōkua nui ai i kou kūlana.

Hōʻike nā haʻawina lapaʻau e hiki i ka cabozantinib ke kōkua i nā kānaka e ola lōʻihi ma mua o sunitinib ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau lua ma hope o nā lāʻau lapaʻau ʻē aʻe. Eia naʻe, ʻaʻole ia he manaʻo e ʻoi aku ka maikaʻi no nā mea a pau.

He ʻokoʻa nā ʻano hopena ʻaoʻao ma waena o kēia mau lāʻau. ʻO ka mea maʻamau ka cabozantinib e hana i ka maʻi lima-wāwae a me ka maʻi maʻi, aʻo ka sunitinib e hana i ka luhi a me nā loli helu koko.

E noʻonoʻo ana kāu kauka i kou olakino holoʻokoʻa, nā lāʻau i hala, a me ka hiki ke ʻae i kekahi mau hopena ʻaoʻao i ke koho ʻana ma waena o kēia mau koho. He ʻokoʻa ka mea e hana maikaʻi loa mai kēlā kanaka i kēia kanaka.

Nā Nīnau i Nīnau pinepine ʻia e pili ana iā Cabozantinib

He palekana anei ʻo Cabozantinib no ka poʻe me ka maʻi puʻuwai?

Hiki i ka Cabozantinib ke hoʻopilikia i kou puʻuwai a me ke koko, no laila pono ka poʻe me nā pilikia puʻuwai i ka nānā pono ʻana. E loiloi kāu kauka i kou olakino puʻuwai ma mua o ka hoʻomaka ʻana i ka lāʻau a e nānā pono iā ʻoe i ka wā o ka lāʻau.

Hiki i ka lāʻau lapaʻau ke hoʻonui i ke koko a hiki ke hoʻoulu i nā pilikia o ka puʻuwai i kekahi poʻe. Inā he moʻolelo kou o ka maʻi puʻuwai, e hana pū kāu cardiologist a me ka oncologist e hōʻoia i ka lāʻau palekana.

Pono ʻoe i nā loiloi koko maʻamau a me nā hoʻokolohua hana puʻuwai i ka wā e lawe ana i ka cabozantinib. Mai kānalua e hōʻike i kekahi ʻeha o ka umauma, ka hanu ʻana, a i ʻole ka puʻuwai ʻole i kāu hui mālama ola koke.

He aha kaʻu e hana ai inā ua lawe hewa au i ka nui o Cabozantinib?

Inā ua lawe hewa ʻoe i ka nui o cabozantinib ma mua o ka mea i kauoha ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau. Mai kali e ʻike inā e ulu nā hōʻailona, no ka mea, hiki i ka lawe ʻana i ka nui ke kumu i nā hopena ʻaoʻao koʻikoʻi.

Hiki i ka overdose ke kumu i ka maʻi maʻi nui, ke koko kiʻekiʻe, a i ʻole nā ​​pilikia ʻē aʻe. Pono kāu hui mālama ola e ʻike koke i hiki iā lākou ke nānā iā ʻoe a hāʻawi i ka lāʻau kūpono.

E lawe mai i ka hue lāʻau me ʻoe inā pono ʻoe e hele i ka haukapila, no ka mea, kōkua kēia i nā limahana lapaʻau e hoʻomaopopo pono i ka mea a me ka nui āu i lawe ai. He mea nui ka manawa me kekahi overdose lāʻau.

He aha kaʻu e hana ai inā ua hala au i kahi mahele o Cabozantinib?

Inā ua hala ʻoe i kahi mahele a ua hala ma lalo o 12 mau hola mai kou manawa dosing maʻamau, e lawe i ka mahele i hala i ka wā e hoʻomanaʻo ai ʻoe. Inā ua hala ma mua o 12 mau hola, e lele i ka mahele i hala a lawe i kāu mahele i hoʻonohonoho ʻia.

Mai lawe i nā lāʻau ʻelua i ka manawa hoʻokahi e pani ai i ka lāʻau i hala, no ka mea, hiki i kēia ke hoʻonui i kou pilikia i nā hopena ʻaoʻao koʻikoʻi. ʻOi aku ka maikaʻi o ka hala ʻana i hoʻokahi lāʻau ma mua o ka pāpālua.

Inā poina pinepine ʻoe i nā lāʻau, e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e noho ma ke ala. He mea nui ka hoʻohana ʻana i kēlā me kēia lā no ka hana pono ʻana o ka lāʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Cabozantinib?

Pono ʻoe e hooki i ka lawe ʻana iā cabozantinib ma lalo o ke alakaʻi a kāu kauka, maʻamau i ka wā e hōʻike ai nā scans e ulu ana kāu maʻi maʻi me ka mālama ʻana a i ʻole i ka wā e lilo ai nā hopena ʻaoʻao i mea hiki ʻole ke mālama. Mai hooki i ka lāʻau lapaʻau ma kāu iho, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi.

E loiloi mau kāu kauka inā e kōkua ana ka lāʻau lapaʻau i ka mālama ʻana i kāu maʻi maʻi ma o nā haʻawina kiʻi a me nā hoʻokolohua koko. Inā pau ka hana ʻana o ka lāʻau a i ʻole ʻoe e hoʻomohala i nā hopena ʻaoʻao koʻikoʻi, e kūkākūkā lākou i nā koho ʻē aʻe.

Ke hopohopo nei kekahi poʻe e pili ana i ka lawe ʻana i ka lāʻau maʻi maʻi no ka wā lōʻihi, akā ua hoʻolālā ʻia ʻo cabozantinib e lilo i lāʻau lapaʻau mālama. ʻO ka hooki ʻana i ka wā ma mua e hiki ke ʻae i kāu maʻi maʻi e ulu wikiwiki.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Cabozantinib?

ʻOi aku ka maikaʻi e pale i ka waiʻona a i ʻole e inu i nā mea liʻiliʻi wale nō i ka wā e lawe ana iā cabozantinib. Hiki i ka waiʻona ke hoʻonui i kekahi mau hopena ʻaoʻao e like me ka nausea a me ka luhi, a hiki ke keakea i ke ʻano o ka hana ʻana o kou ate i ka lāʻau.

Hiki i ka waiʻona a me ka cabozantinib ke hoʻopilikia i kou ate, no laila ʻo ka hui pū ʻana iā lākou e hoʻonui i ka pilikia o nā pilikia o ke ake. Mālama kāu kauka i kāu hana ate i kēlā me kēia manawa, a hiki i ka waiʻona ke paʻakikī i kēia mau hoʻokolohua.

Inā koho ʻoe e inu i kekahi manawa, e kūkākūkā mua me kāu hui mālama ola. Hiki iā lākou ke aʻo iā ʻoe i nā palena palekana e pili ana i kou olakino holoʻokoʻa a me ke ʻano o kou pane ʻana i ka lāʻau.