He aha ke kanu ʻana o Carmustine: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO ke kanu ʻana o Carmustine he lapaʻau kūikawā kahi e waiho ʻia ai nā wafers liʻiliʻi i loaʻa ka lāʻau chemotherapy carmustine i loko o ka lolo ma ke ʻoki ʻana. Hāʻawi kēia ala i ka lāʻau lapaʻau e hana pololei ma kahi o ka maʻi ʻaʻai, e hāʻawi ana i ka mana hakakā maʻi ʻaʻai i ka wā e hōʻemi ana i nā hopena ma ke koena o kou kino. Hoʻohana nui ʻia ia no kekahi mau ʻano maʻi ʻaʻai lolo, e hāʻawi ana i ka manaʻolana i ka wā e lawa ʻole ai nā lāʻau lapaʻau kuʻuna.

He aha ke kanu ʻana o Carmustine?

ʻO ke kanu ʻana o Carmustine e pili ana i ka waiho ʻana i nā wafers liʻiliʻi, biodegradable i loaʻa ka carmustine i loko o ka lolo i ka wā o ke ʻoki ʻana. ʻO kēia mau wafers e like me ka nui o ka dime a e hoʻoheheʻe mālie i ka manawa, e hoʻokuʻu ana i ka lāʻau lapaʻau ma kahi e pono ai.

Hana ʻia nā wafers mai kahi polymer kūikawā e wāwahi maoli i loko o kou kino. I ka wā e hoʻoheheʻe ai lākou i nā pule he nui, hoʻokuʻu mau lākou i ka carmustine e hakakā i nā cell maʻi ʻaʻai i koe i loko o ka ʻiʻo lolo a puni. Kōkua kēia ala i ka hoʻonui ʻana i ka pono o ka lāʻau lapaʻau i ka wā e hōʻemi ana i nā hopena ʻaoʻao āu e ʻike ai me ka chemotherapy kuʻuna.

E waiho kāu kauka lapaʻau i kēia mau wafers i loko o ka lua i waiho ʻia ma hope o ka wehe ʻana i ka maʻi ʻaʻai lolo. ʻO ka helu o nā wafers i hoʻohana ʻia e pili ana i ka nui o ka wahi e mālama ʻia nei, maʻamau mai hoʻokahi a ʻewalu wafers no ke kaʻina hana.

No ke aha i hoʻohana ʻia ai ke kanu ʻana o Carmustine?

Hoʻohana nui ʻia ke kanu ʻana o Carmustine e mālama i nā gliomas malignant, kahi ʻano o ka maʻi ʻaʻai lolo koʻikoʻi. Manaʻo nui ʻia ia no nā maʻi i hōʻike ʻia i nā gliomas kiʻekiʻe a i ʻole nā ​​mea i hoʻihoʻi ʻia kā lākou mau maʻi ma hope o ka lāʻau lapaʻau mua.

He hana maikaʻi kēia lapaʻau ke hui pū ʻia me ke ʻoki ʻana e wehe i ka nui o ka maʻi maʻi e like me ka hiki. Ma hope o ka wehe ʻana o kāu kauka lapaʻau i ka maʻi maʻi i ʻike ʻia, kōkua nā wafers carmustine i ka pahuhopu i nā pūnaewele maʻi maʻi microscopic e noho ana i loko o ka ʻiʻo a puni. Hiki i kēia hui pū ʻana ke kōkua i ka hoʻolōʻihi ʻana i ke ola a hoʻomaikaʻi i ka maikaʻi o ke ola no nā maʻi he nui.

Hiki i kāu oncologist ke noʻonoʻo i kēia lapaʻau no nā ʻano maʻi maʻi lolo ʻē aʻe, ʻoiai ʻaʻole maʻamau kēia. Aia ka hoʻoholo i nā mea e like me kahi o ka maʻi maʻi, ka nui, a me ka maikaʻi o kāu pane ʻana i nā lapaʻau ʻē aʻe.

Pehea e hana ai ka Carmustine Implantation?

He lāʻau chemotherapy ikaika ʻo Carmustine e hana ana ma ka hōʻino ʻana i ka DNA i loko o nā pūnaewele maʻi maʻi, e pale ana iā lākou mai ka mahele a me ka ulu ʻana. Ke hāʻawi ʻia ma o ka implantation, hāʻawi ia i ka lapaʻau kiʻekiʻe, kiʻekiʻe i ka wahi maʻi maʻi.

Hoʻokuʻu mālie nā wafers i ka carmustine ma kahi o ʻekolu pule, e hana ana i kahi pae therapeutic mau i loko o ka ʻiʻo lolo. Kōkua kēia hoʻokuʻu paʻa e hōʻoia i ka hoʻopili mau ʻia ʻana o nā pūnaewele maʻi maʻi i koe i ka lāʻau, e paʻakikī ai iā lākou ke ola a i ʻole ka ulu hou ʻana.

No ka mea, ua hāʻawi ʻia ka lāʻau i kahi kūloko ma mua o kou kahe koko, hiki i nā kiʻekiʻe kiʻekiʻe ke hiki i ka wahi maʻi maʻi. ʻO kēia hana i manaʻo ʻia, ʻo ia hoʻi, hiki i ka lāʻau ke ʻoi aku ka maikaʻi i nā pūnaewele maʻi maʻi me ka hana ʻana i nā hopena ʻaoʻao liʻiliʻi ma kou kino ma mua o ka chemotherapy intravenous kuʻuna.

Pehea wau e hoʻomākaukau ai no ka Carmustine Implantation?

Hoʻomaka ka hoʻomākaukau ʻana no ka carmustine implantation me ka loiloi olakino piha a me ka hoʻolālā ʻoki. E nānā kāu hui mālama ola i kāu mōʻaukala olakino, nā lāʻau lapaʻau o kēia manawa, a hana i nā haʻawina kiʻi e palapala i ke ala ʻoki.

Ma mua o ke kaʻina hana, pono ʻoe e hahai i nā ʻōlelo aʻoaʻo maʻamau ma mua o ke kālai ʻana. ʻO ka mea maʻamau, e komo ana kēia i ka hoʻokē ʻai ʻana no 8-12 mau hola ma mua o ke kālai ʻana a me ka hoʻōki ʻana i kekahi mau lāʻau lapaʻau e hiki ke hoʻonui i ka pilikia o ke kahe ʻana. E hāʻawi kāu kauka iā ʻoe i kahi papa inoa kikoʻī o nā lāʻau lapaʻau e pale aku ai a me ka manawa e hoʻōki ai i ka lawe ʻana iā lākou.

E hui pū ʻoe me kāu anesthesiologist e kūkākūkā i nā koho anesthesia a e pane i nā hopohopo. E hōʻoia e hoʻonohonoho i kekahi e hoʻokele iā ʻoe i ka home ma hope o ke kaʻina hana a noho pū me ʻoe no nā hola 24-48 mua i kou ola ʻana mai ke kālai ʻana.

Pehea ka lōʻihi e pono ai au e lawe i ka lāʻau lapaʻau Carmustine Implantation?

ʻO ka hoʻokomo ʻana o Carmustine he hana hoʻokahi i ka wā o ke kālai ʻana i ka maʻi lolo. Hoʻokomo ʻia nā wafers i hoʻokahi manawa a laila e hoʻoheheʻe maoli ʻia i nā pule e hiki mai ana, e hoʻokuʻu mau ana i ka lāʻau lapaʻau i kēia manawa.

ʻO ka hopena lapaʻau e mau ana ma kahi o ʻekolu pule i ka wā e wāwahi mālie ai nā wafers. I loko o kēia manawa, ʻaʻole pono ʻoe e lawe i nā lāʻau carmustine hou, no ka mea, hāʻawi nā wafers i hoʻokomo ʻia i ka lāʻau lapaʻau paʻa.

Pono paha nā lāʻau lapaʻau e pili ana i ka pane ʻana o kāu maʻi. E nānā kāu oncologist i kāu holomua ma o nā haʻawina kiʻi maʻamau a hiki ke ʻōlelo i nā lāʻau lapaʻau hou e like me ka radiation a i ʻole nā lāʻau chemotherapy ʻē aʻe ma ke ʻano he ʻāpana o kāu hoʻolālā lapaʻau holoʻokoʻa.

He aha nā hopena ʻaoʻao o ka Carmustine Implantation?

ʻO nā hopena ʻaoʻao mai ka hoʻokomo ʻana o carmustine e pili ana i ke kaʻina hana a me nā hopena kūloko o ka lāʻau lapaʻau ma nā ʻiʻo lolo. ʻO ka hapa nui o nā maʻi e ʻike i nā hopena ʻaoʻao hiki ke mālama ʻia e hoʻomaikaʻi i ka manawa me ka mālama kūpono a me ka nānā ʻana.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia nā poʻo, hiki ke hele mai mai ka maʻalahi a i ka maʻalahi a pane maikaʻi i ka lāʻau lapaʻau. ʻO ka pehu ʻana o ka lolo kekahi mea e hana pinepine ʻia e nānā pono ai kāu hui lapaʻau a mālama me nā corticosteroids inā pono.

Eia nā hopena ʻaoʻao maʻamau e pono ai e ʻike:

• ʻEha poʻo e mau ana no kekahi mau lā a i ʻole mau pule
• Pehu lolo (cerebral edema) e koi ana i ka lāʻau steroid
• Nā ʻāʻī i kekahi poʻe maʻi, ʻoiai ʻaʻole i loaʻa ka mōʻaukala ma mua
• Luhi a me ka nāwaliwali i ka wā e ola ai kou kino mai ke ʻoki
• ʻO ka nausea a me ka luaʻi ʻana, maʻamau ka maʻalahi a me ka manawa
• Nā pilikia hoʻōla ʻeha ma ke kahua ʻoki

He manawa pōkole wale nō kēia mau hopena ʻaoʻao a hoʻomaikaʻi i ka wā e hoʻōla ai ke kahua ʻoki a hoʻoponopono kou kino i ka lāʻau. E hāʻawi kāu hui mālama ola i nā lāʻau lapaʻau a me ke kākoʻo e kōkua i ka mālama pono ʻana i kēia mau hopena.

ʻO nā hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e pili ana i ka maʻi ma ke kahua ʻoki, e koi ana i ka lāʻau lapaʻau koke. ʻO nā hōʻailona o ka maʻi e pili ana i ke kuni, ka hoʻonui ʻana i ka wai mai ka ʻeha, a i ʻole ka ʻeha poʻo e ʻino nei. Eia kekahi, hiki i kekahi poʻe maʻi ke ʻike i nā loli i ka hana cognitive a i ʻole ka pilikino, ʻoiai he manawa pōkole kēia.

ʻO wai ka mea ʻaʻole pono e loaʻa i ka Carmustine Implantation?

ʻAʻole kūpono ka implantation Carmustine no nā mea a pau me nā maʻi lolo. E loiloi pono kāu hui lapaʻau inā kūpono kēia lāʻau lapaʻau ma muli o kou kūlana kikoʻī a me ke olakino holoʻokoʻa.

ʻAʻole kūpono paha nā maʻi me kekahi mau maʻi lapaʻau no kēia kaʻina hana. Inā loaʻa iā ʻoe nā maʻi maʻi, nā maʻi koko nui, a i ʻole nā pilikia o ka puʻuwai a i ʻole ka māmā e hoʻoweliweli loa ai ke ʻoki, hiki i kāu kauka ke ʻōlelo i nā lāʻau lapaʻau ʻē aʻe.

ʻAʻole kūpono paha nā kānaka me nā maʻi ma kekahi mau wahi lolo no ka implantation carmustine. ʻO nā maʻi i loaʻa ma nā wahi kahi e hiki ai i ka waiho ʻana o ka wafer ke hōʻeha nui i ka neurological a i ʻole nā mea hohonu loa a i ʻole ākea paha e koi ai i nā ʻano lāʻau lapaʻau like ʻole.

E noʻonoʻo nō hoʻi kāu kauka oncologists i kāu mau lapaʻau i hala a me ka maikaʻi o kou hoʻomanawanui ʻana iā lākou. Inā ua loaʻa iā ʻoe nā hopena koʻikoʻi i ka carmustine a i ʻole nā lāʻau lapaʻau like i ka wā ma mua, a i ʻole inā ua loaʻa iā ʻoe ka nui o ka lāʻau palekana o kekahi mau lāʻau chemotherapy, hiki i nā koho ʻē aʻe ke kūpono.

Nā inoa inoa o ka Carmustine Implantation

Loaʻa ka ʻōnaehana implantation carmustine ma lalo o ka inoa inoa Gliadel. ʻO kēia nā wafers biodegradable i loaʻa ka carmustine a ua hoʻolālā kūikawā ʻia no ka hoʻokomo ʻana i ka ʻokiʻoki i loko o ka ʻiʻo lolo.

Hana ʻia nā wafers Gliadel e Eisai Inc. a ua ʻae ʻia e ka FDA no ka mālama ʻana i kekahi mau maʻi lolo. Loaʻa i kēlā me kēia wafer he 7.7 mg o ka carmustine me kahi polymer kūikawā e hiki ai ke hoʻokuʻu ʻia ka lāʻau lapaʻau i ka manawa.

E kuhikuhi kāu hui mālama ola i kēia lapaʻau ma nā inoa like ʻole me Gliadel wafers, carmustine wafers, a i ʻole BCNU wafers. ʻO BCNU kekahi inoa no ka carmustine, no laila pili kēia mau huaʻōlelo a pau i ke ʻano lapaʻau like.

Nā koho ʻē aʻe o ka Carmustine Implantation

Loaʻa nā lapaʻau ʻē aʻe no nā maʻi lolo i ka wā ʻaʻole kūpono a makemake ʻole ʻia ka implantation carmustine. ʻO ke koho maikaʻi loa e pili ana i kāu ʻano maʻi kikoʻī, kahi, a me ke kūlana olakino holoʻokoʻa.

ʻO ka radiation therapy kahi koho maʻamau i hiki ke hāʻawi ʻia ma waho a i ʻole ma o nā ʻenehana loea e like me ka stereotactic radiosurgery. Hoʻohana kēia ʻano i nā kukuna ikehu kiʻekiʻe e kuhikuhi i nā cell cancer i ka wā e hōʻemi ana i ka pōʻino i ka ʻiʻo lolo olakino.

Hāʻawi ka chemotherapy intravenous kuʻuna i kahi koho ʻē aʻe, me ka hoʻohana ʻana i nā lāʻau e like me temozolomide a i ʻole bevacizumab. ʻOiai e pili ana kēia mau lāʻau i kou kino holoʻokoʻa, hiki iā lākou ke maikaʻi no kekahi mau maʻi lolo a hiki ke hui pū ʻia me ka radiation no nā hopena i hoʻonui ʻia.

Hiki ke noʻonoʻo ʻia nā lāʻau lapaʻau hou e like me ka therapy kahua e mālama ana i ka maʻi (TTF) a i ʻole ka immunotherapy. Hana ʻokoʻa kēia mau ala mai ka chemotherapy kuʻuna a kūpono paha no nā ʻano maʻi lolo kikoʻī a i ʻole i kekahi mau kūlana.

ʻOi aku ka maikaʻi o ka hoʻokomo ʻana i ka Carmustine ma mua o Temozolomide?

Hana ʻokoʻa ka hoʻokomo ʻana i ka Carmustine a me ka temozolomide a hoʻohana pinepine ʻia ma nā ʻano hana hoʻohui ma mua o nā lāʻau lapaʻau hoʻokūkū. Ua hōʻoia ʻia nā pōmaikaʻi no nā maʻi maʻi lolo, akā ʻo ke koho maikaʻi loa e pili ana i kou mau kūlana pilikino.

Hāʻawi ka hoʻokomo ʻana i ka Carmustine i nā kiʻekiʻe kiʻekiʻe o ka lāʻau lapaʻau pololei i ka pūnaewele tumor, kahi e hiki ai ke maikaʻi loa no nā gliomas kiʻekiʻe i hōʻoia hou ʻia. ʻO ke ala kūloko e hōʻemi ana i nā hopena ʻaoʻao systemic i hoʻohālikelike ʻia me ka chemotherapy waha a i ʻole intravenous.

ʻO Temozolomide, ma ka ʻaoʻao ʻē aʻe, lawe ʻia ma ke ʻano he pila a hana ma kou kino holoʻokoʻa. Hoʻohana pinepine ʻia ma ke ʻano he lāʻau lapaʻau e hoʻomau ana ma hope o ke ʻoki ʻana a me ka radiation, e hāʻawi ana i ka mana maʻi maʻi systemic. Nui nā maʻi e loaʻa ana i nā lāʻau lapaʻau ʻelua ma ke ʻano he ʻāpana o kahi hoʻolālā lapaʻau piha.

Hōʻike ka noiʻi ʻana i ka hui ʻana i ka hoʻokomo ʻana i ka carmustine me nā lāʻau lapaʻau maʻamau me ka temozolomide e hāʻawi i nā hopena maikaʻi aʻe ma mua o kekahi lāʻau lapaʻau wale nō. E kōkua kāu oncologist e hoʻoholo i ka hui maikaʻi loa o nā lāʻau lapaʻau e pili ana i kāu mau ʻano tumor kikoʻī a me nā pahuhopu lapaʻau.

Nā nīnau i nīnau pinepine ʻia e pili ana i ka hoʻokomo ʻana i ka Carmustine

He palekana anei ka hoʻokomo ʻana i ka Carmustine no nā maʻi ʻelemakule?

Hiki ke palekana ka hoʻokomo ʻana i ka Carmustine no nā maʻi ʻelemakule, akā pono e noʻonoʻo pono nā mea e pili ana i ka makahiki. He kiʻekiʻe paha ka pilikia o nā pilikia o ka ʻoki ʻana i nā mākua kahiko a hiki ke lōʻihi ka hoʻōla ʻana mai ke kaʻina hana.

E loiloi kāu hui lapaʻau i kou kūlana olakino holoʻokoʻa, me ka hana o ka naʻau, ka māmā, a me ka puʻupaʻa, ma mua o ka nānā ʻana i ka makahiki wale nō. Nui nā maʻi ʻelemakule e ʻae maikaʻi i ke kaʻina hana a pōmaikaʻi mai ke ala lapaʻau i manaʻo ʻia. Pono e hana ʻia ka hoʻoholo ma ke kanaka, ma muli o kou kūlana hana, nā maʻi olakino ʻē aʻe, a me nā pahuhopu lapaʻau.

He aha kaʻu e hana ai inā loaʻa iaʻu nā ʻeha poʻo nui ma hope o ke kanu ʻana o Carmustine?

Pono nā ʻeha poʻo nui ma hope o ke kanu ʻana o carmustine i ka mālama olakino koke, no ka mea, hiki iā lākou ke hōʻike i ka pehu o ka lolo a i ʻole nā pilikia ʻē aʻe. E hoʻokaʻaʻike koke i kāu hui mālama ola inā loaʻa iā ʻoe nā ʻeha poʻo e ʻinoʻino nei, ʻaʻole e pane i nā lāʻau lapaʻau i kuhikuhi ʻia, a i ʻole e hele pū ʻia me ka nausea, ka luaʻi, a i ʻole nā loli ʻike.

Pono paha kāu kauka e hoʻoponopono i kāu mau lāʻau lapaʻau, ʻo ia hoʻi nā corticosteroids e kōkua i ka hōʻemi ʻana i ka pehu o ka lolo. I kekahi mau hihia, pono paha nā haʻawina kiʻi hou e hōʻoia i ka hoʻōla kūpono a kāpae i nā pilikia. Mai hoʻāʻo e mālama i nā ʻeha poʻo nui iā ʻoe iho - he mea nui ka loiloi olakino wikiwiki no kou palekana a me ka hoʻōla.

He aha kaʻu e hana ai inā loaʻa iaʻu kahi hopu ma hope o ke kanu ʻana o Carmustine?

Inā loaʻa iā ʻoe kahi hopu ma hope o ke kanu ʻana o carmustine, e ʻimi koke i ka mālama olakino pilikia. ʻOiai inā pau ka hopu ʻana iā ia iho, pono ʻoe i ka loiloi olakino e hoʻoholo i ke kumu a pale i nā hanana e hiki mai ana.

E kuhikuhi paha kāu hui mālama ola i nā lāʻau anti-seizure e kōkua i ka pale ʻana i nā hopu e hiki mai ana. Hoʻomau pinepine ʻia kēia mau lāʻau lapaʻau no kekahi mau mahina a ʻoi aku paha, ma muli o kāu mau mea pilikia pilikino. E hahai i kāu papa manawa lāʻau lapaʻau e like me ke kuhikuhi ʻia, a mai hoʻōki koke i nā lāʻau anti-seizure me ka ʻole o ka mālama olakino.

I ka manawa hea e hiki ai iaʻu ke hoʻi i nā hana maʻamau ma hope o ke kanu ʻana o Carmustine?

He ʻokoʻa ka manawa hoʻōla no kēlā me kēia kanaka, akā hiki i ka hapa nui o nā maʻi ke hoʻi mālie i nā hana māmā i loko o 2-4 mau pule ma hope o ke ʻoki. E hāʻawi kāu hui mālama ola i nā alakaʻi kikoʻī e pili ana i kāu holomua hoʻōla a me ke kūlana holoʻokoʻa.

I ka wā mua, pono ʻoe e pale i nā hana ikaika, ka hāpai ʻana i nā mea kaumaha, a me nā hana e hiki ke hoʻonui i ke kaomi i kou poʻo. Pili pinepine nā palena o ka hoʻokele a hiki i ka wā e hoʻomaʻemaʻe ai kāu kauka iā ʻoe, ma hope o ka hōʻoia ʻana ʻaʻole ʻoe e loaʻa ana i nā hopu a ʻaʻole hoʻopilikia kāu mau lāʻau i kou hiki ke hoʻokele palekana. Aia ka hoʻi ʻana i ka hana i kāu mau koi hana a me ke ʻano o kou manaʻo, akā hiki i nā maʻi he nui ke hoʻomau i ka hana pākaukau i loko o kekahi mau pule.

Pehea e nānā ai ke kauka i koʻu holomua ma hope o ka hoʻokomo ʻana i ka Carmustine?

E nānā kāu hui lapaʻau i kou holomua ma o nā manawa ukali maʻamau a me nā haʻawina kiʻi. ʻO ka maʻamau, e loaʻa iā ʻoe nā scans MRI i kēlā me kēia 2-3 mahina i ka wā mua, a laila ʻaʻole pinepine i ka hala ʻana o ka manawa a paʻa kou kūlana.

I ka wā o nā kipa ukali, e loiloi kāu kauka i kāu hana neurological, e nānā i nā hōʻailona āu e ʻike nei, a e nānā i nā hōʻailona o ka hoʻi hou ʻana o ka maʻi maʻi. Hiki ke hana ʻia nā hoʻokolohua koko i kēlā me kēia manawa e nānā i nā hopena mai ka lāʻau lapaʻau. Kōkua kēia nānā ʻana i ka ʻike mua ʻana i nā loli a hiki ke hoʻoponopono koke i kāu hoʻolālā lapaʻau inā pono.