He aha ka Colistimethate: Nā Hoʻohana, Ka Leka, Nā ʻAoʻao ʻAoʻao a me nā mea hou aku

He lāʻau antibiotic ikaika ka Colistimethate a nā kauka e hoʻohana ai i ka wā i hana ʻole ai nā lāʻau lapaʻau ʻē aʻe i nā maʻi bacteria koʻikoʻi. No ka hui o nā lāʻau lapaʻau i kapa ʻia ʻo polymyxins, i manaʻo ʻia he antibiotics "hope loa" no nā maʻi e hoʻoweliweli ana i ke ola i hana ʻia e nā bacteria e kūʻē i ka hapa nui o nā lāʻau ʻē aʻe.

Hāʻawi ʻia kēia lāʻau lapaʻau ma ke ʻano he injection, i loko o ka vein a i ʻole ka ʻiʻo, no ka mea pono e hana wikiwiki a maikaʻi i loko o kou kino. ʻOiai he lāʻau ikaika ia e hiki ke hoʻopakele i nā ola, hele mai nō me kekahi mau pilikia e nānā pono ai kāu hui mālama ola.

No ke aha e hoʻohana ʻia ai ka Colistimethate?

Hoʻomaʻamaʻa ʻo Colistimethate i nā maʻi koʻikoʻi i hana ʻia e nā bacteria gram-negative ʻaʻole e pane i nā antibiotics ʻē aʻe. E kauoha maʻamau kāu kauka i kēia lāʻau lapaʻau ke loaʻa iā ʻoe kahi maʻi koʻikoʻi a ʻaʻole i maikaʻi nā lāʻau lapaʻau ʻē aʻe.

ʻO nā maʻi maʻamau i mālama ʻia me ka colistimethate me ka pneumonia, nā maʻi kahe koko, nā maʻi urinary tract, a me nā maʻi ʻili. He mea pono loa ia i nā bacteria e like me Pseudomonas aeruginosa, Acinetobacter, a me kekahi mau ʻano o E. coli i lilo i mea kūʻē i nā antibiotics he nui.

I kekahi manawa hoʻohana nā kauka i ka colistimethate e pale i nā maʻi i ka poʻe i pilikia loa, e like me ka poʻe me ka cystic fibrosis a i ʻole nā ​​maʻi i nā ʻāpana mālama koʻikoʻi. Eia naʻe, ʻaʻole maʻamau kēia hoʻohana pale a pono e noʻonoʻo pono i nā pōmaikaʻi e kūʻē i nā pilikia.

Pehea e hana ai ka Colistimethate?

Hana ʻo Colistimethate ma ka hoʻouka ʻana i ka paia waho o nā cell bacteria, e hana ana iā lākou e haki a make. E noʻonoʻo e like me ka hoʻopaʻa ʻana i nā lua i loko o ka baluna - i ka wā i pōʻino ai ka paia cell bacterial, ʻaʻole hiki i ka bacteria ke ola.

He lāʻau antibiotic ikaika kēia i hoʻolālā ʻia e hakakā i nā bacteria i loaʻa ka pale ʻana i nā lāʻau ʻē aʻe. ʻO ia ka mea a nā kauka e kapa ai he antibiotic "bactericidal", ʻo ia hoʻi, pepehi maoli ia i nā bacteria ma mua o ka hoʻōki ʻana i ko lākou ulu ʻana.

Hoʻololi ʻia ka lāʻau lapaʻau i kona ʻano hana i kapa ʻia ʻo colistin ke komo i loko o kou kino. Kōkua kēia hana hoʻololi i ka hōʻemi ʻana i kekahi o nā hopena ʻaoʻao ʻoiai e mālama ana i nā hopena antibacterial ikaika o ka lāʻau.

Pehea wau e lawe ai iā Colistimethate?

E loaʻa iā ʻoe ka colistimethate ma ke ʻano he injection i loko o kahi haukapila a i ʻole kahi hoʻonohonoho lapaʻau, ʻaʻole loa ma ke ʻano he pill āu e lawe ai ma ka home. Hāʻawi ʻia ka lāʻau lapaʻau ma o ka laina IV i loko o kou vein a i ʻole ma ke ʻano he injection i loko o kou ʻiʻo, ma muli o kou kūlana.

E helu kāu hui mālama ola i kāu mahele pololei e pili ana i kou kaumaha, ka hana o ka puʻupaʻa, a me ke koʻikoʻi o kāu maʻi. ʻO ka mālama maʻamau e pili ana i ka loaʻa ʻana o ka lāʻau lapaʻau 2-4 manawa i ka lā, me kēlā me kēia mahele i hāʻawi ʻia mālie ma luna o 30 mau minuke a 2 mau hola inā ma o IV.

ʻAʻole pono ʻoe e hopohopo e pili ana i ka lawe ʻana i kēia lāʻau me ka meaʻai no ka mea ua hāʻawi ʻia ma ke ʻano he injection. Eia naʻe, he mea nui e noho maikaʻi i ka wai i ka wā o ka mālama ʻana, no laila e inu i ka wai nui ke ʻole kāu kauka e haʻi iā ʻoe.

E nānā pono kāu hui lapaʻau iā ʻoe i ka wā o ka mālama ʻana, e nānā mau ana i kou koko e hōʻoia i ka hana pono ʻana o ka lāʻau a ʻaʻole e hana i nā hopena ʻaoʻao.

Pehea ka lōʻihi e lawe ai au iā Colistimethate?

ʻO ka lōʻihi o ka mālama ʻana me ka colistimethate maʻamau mai 7 a 14 mau lā, akā hiki ke ʻokoʻa nui kēia ma muli o kāu maʻi kikoʻī a pehea ʻoe e pane ai i ka mālama ʻana. E hoʻoholo kāu kauka i ka lōʻihi pololei e pili ana i nā mea he nui.

No ka nui o nā maʻi bacteria, pono ʻoe e hoʻomau i ka lapaʻau a hiki i ka hōʻike ʻana o nā hoʻokolohua lab i ka pau ʻana o ka bacteria a ua hoʻomaikaʻi ʻia kou mau hōʻailona. Pono paha kekahi mau maʻi koʻikoʻi i nā manawa lapaʻau lōʻihi, a pane wikiwiki paha kekahi.

E nānā kāu hui mālama ola i kou holomua ma o nā hoʻokolohua koko maʻamau, nā haʻawina kiʻi, a me nā hoʻokolohua kino. E nānā pū lākou i nā hōʻailona e hoʻomaʻemaʻe ana ka maʻi, e like me ka emi ʻana o ke kuni, ka hanu maikaʻi ʻana, a i ʻole ka hoʻōla ʻana o nā ʻeha i maʻi ʻia.

He mea nui e hoʻopau i ka papa lapaʻau piha ʻoiai inā e hoʻomaka ana ʻoe e ʻoi aku ka maikaʻi. ʻO ka hoʻōki ʻana i ka wā mua hiki ke ʻae i ka bacteria e hoʻi mai me ka ikaika a me ka pale ʻana i ka lapaʻau.

He aha nā hopena ʻaoʻao o Colistimethate?

E like me nā lāʻau lapaʻau ikaika a pau, hiki i ka colistimethate ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole ʻike nā kānaka a pau iā lākou. ʻO nā hopena ʻaoʻao maʻamau ka mea hiki ke mālama ʻia a e nānā pono kāu hui lapaʻau iā lākou.

Eia nā hopena ʻaoʻao āu e ʻike ai, e hoʻomaka ana me nā mea maʻamau:

• Nā pilikia o ka puʻupaʻa, me nā loli i ka mimi a i ʻole ka pehu ʻana i kou mau wāwae a i ʻole nā wāwae
• ʻO ka wili a i ʻole ka manaʻo ʻole, ʻoiai ke kū nei
• Ka ʻūlū a i ʻole ka ʻūlū ʻana i kou mau lima, nā wāwae, a i ʻole a puni kou waha
• Nausea a i ʻole ka ʻōpū
• ʻEha a i ʻole ka huhū ma kahi i hoʻokomo ʻia ai
• ʻEha poʻo a i ʻole ka manaʻo huikau
• ʻO ka nāwaliwali o ka ʻiʻo a i ʻole ka pilikia me ka hoʻohui

ʻO ka hapa nui o kēia mau hopena he maʻalahi a he manawa pōkole, akā e nānā pono kāu hui mālama ola iā ʻoe e hopu i nā pilikia i ka wā mua. E nānā mau lākou i kāu hana puʻupaʻa a me nā pane nerve i ka wā lapaʻau.

ʻO kekahi mau hopena ʻaoʻao kakaʻikahi akā koʻikoʻi e pili ana i ka pōʻino nui o ka puʻupaʻa, nā pilikia hanu, a i ʻole nā loli nui i kou kūlana noʻonoʻo. Ua aʻo ʻia kāu hui lapaʻau e ʻike i kēia mau hōʻailona a e hana koke lākou inā e hana lākou.

ʻO wai ka mea pono ʻole e lawe i ka Colistimethate?

ʻAʻole kūpono ʻo Colistimethate no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. Pono paha nā kānaka me kekahi mau maʻi olakino i nā lāʻau lapaʻau like ʻole a i ʻole ka nānā ʻana.

ʻAʻole pono ʻoe e loaʻa i ka colistimethate inā he maʻi ʻoe i ka colistin, nā lāʻau antibiotic polymyxin, a i ʻole kekahi mea i loko o ka lāʻau. E haʻi i kāu hui mālama ola e pili ana i nā hopena maʻi i nā lāʻau antibiotic, ʻoiai inā ʻaʻole pili.

Pono nā kānaka me nā pilikia kīkī e noʻonoʻo kūikawā, no ka mea, hiki i ka colistimethate ke hoʻopilikia i ka hana kīkī. E kaupaona kāu kauka i nā pōmaikaʻi e kūʻē i nā pilikia a hiki ke hoʻoponopono i kāu mahele a i ʻole ke koho ʻana i kahi lāʻau lapaʻau ʻē aʻe inā ʻaʻole hana maikaʻi kāu mau kīkī.

Inā loaʻa iā ʻoe ka myasthenia gravis (kahi maʻi nāwaliwali ʻiʻo), nā pilikia nerve, a i ʻole nā pilikia lohe, pono kāu kauka e nānā pono iā ʻoe. Hiki ke hoʻonui ʻia kēia mau maʻi e ka colistimethate, ʻoiai paha e pono ke mālama ʻia inā loaʻa iā ʻoe kahi maʻi koʻikoʻi.

Pono nā wahine hāpai a me nā wahine e hānai ana i ka waiū i ka noʻonoʻo kūikawā, no ka mea, he palena ka ʻike e pili ana i ka palekana o ka colistimethate i ka wā hāpai. E kauoha wale kāu kauka inā ʻoi aku ka maikaʻi ma mua o nā pilikia.

Nā inoa inoa o Colistimethate

Loaʻa ka Colistimethate ma lalo o nā inoa inoa like ʻole, ʻo Coly-Mycin M kekahi o nā mea maʻamau ma ʻAmelika Hui Pū ʻIa. ʻO nā inoa inoa ʻē aʻe e pili ana iā Colistin a me Promixin, ʻoiai ʻokoʻa ka loaʻa ʻana ma kēlā me kēia ʻāina.

ʻO ka inoa generic

I ka wā ʻaʻole kūpono a loaʻa ʻole ka colistimethate, hiki i kāu kauka ke noʻonoʻo i nā lāʻau antibiotic ʻē aʻe, ʻoiai ua kaupalena ʻia nā koho no nā bacteria kūpaʻa. Aia ke koho i nā bacteria e hoʻoulu nei i kāu maʻi a me ko lākou ʻike i nā lāʻau lapaʻau like ʻole.

ʻO kekahi mau koho ʻē aʻe e komo pū ana me ka tigecycline, e hana ana i nā bacteria kūpaʻa he nui, a i ʻole nā ​​lāʻau lapaʻau hui pū e hoʻohana ana i nā lāʻau antibiotic he nui. Hiki i nā lāʻau lapaʻau hou e like me ceftazidime-avibactam a i ʻole meropenem-vaborbactam ke lilo i mau koho no kekahi mau ʻano maʻi.

I kekahi mau hihia, hiki i kāu kauka ke hoʻāʻo i ka polymyxin B, pili pili loa i ka colistimethate a hana like. Eia naʻe, ua like loa nā ʻaoʻao hopena, no laila ʻaʻole kēia he koho maikaʻi inā he pilikia kāu me ka colistimethate.

ʻO ka ʻoiaʻiʻo, no nā maʻi kūpaʻa loa, ʻo ka colistimethate kekahi o nā lāʻau lapaʻau maikaʻi loa i loaʻa. E hoʻāʻo mau kāu hui lapaʻau e ʻimi i ke koho palekana a maikaʻi no kāu kūlana kikoʻī.

Ua ʻoi aku ka maikaʻi o ka Colistimethate ma mua o nā Antibiotics ʻē aʻe?

ʻAʻole pono ka colistimethate i

E hoʻāʻo mau kāu kauka e hoʻohana i ka lāʻau antibiotic maʻalahi loa i ka mua, e neʻe ana i nā koho ikaika e like me colistimethate ke pono wale nō. Kōkua kēia hana i ka mālama ʻana i ka pono o kēia mau lāʻau ikaika no ka wā e pono maoli ai lākou.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Colistimethate

He Palekana ʻo Colistimethate no ka poʻe me ka maʻi kīkī?

Hiki i ka Colistimethate ke hoʻopilikia i ka hana kīkī, no laila pono ka poʻe me nā pilikia kīkī i ka mālama kūikawā a me ka nānā ʻana. E hoʻoponopono kāu kauka i kāu mahele ma muli o ka maikaʻi o ka hana ʻana o kou mau kīkī a e nānā mau i ka hana o kou mau kīkī i ka wā o ka mālama ʻana.

Inā he mau pilikia kīkī liʻiliʻi kāu, hiki paha iā ʻoe ke loaʻa iā colistimethate me ka mahele i hoʻemi ʻia a me ka nānā hou. Eia naʻe, inā ua pilikia nui ka hana o kou mau kīkī, pono paha i kāu kauka ke noʻonoʻo i nā lāʻau lapaʻau ʻē aʻe a i ʻole e hoʻohana iā colistimethate inā pono loa.

He aha kaʻu e hana ai inā loaʻa iaʻu nā hopena ʻaoʻao koʻikoʻi?

Mai ka mea e loaʻa iā ʻoe ka colistimethate i loko o kahi haukapila a i ʻole kahi hoʻonohonoho lapaʻau, e nānā pono kāu hui lapaʻau iā ʻoe no nā hopena ʻaoʻao. Inā ʻike ʻoe i nā hōʻailona e pili ana e like me ka pilikia o ka hanu ʻana, ka ʻūlū nui, a i ʻole nā loli nui i ka mimi ʻana, e haʻi koke i kāu kahu hānai a i ʻole kauka.

Mai hopohopo e pili ana i ka hoʻopilikia ʻana i nā limahana lapaʻau - makemake lākou e ʻike e pili ana i nā hōʻailona āu e ʻike nei. Hiki i ka ʻike mua a me ka mālama ʻana i nā hopena ʻaoʻao ke pale i nā pilikia koʻikoʻi mai ka ulu ʻana.

He aha ka mea e hana ai inā e hala wau i kahi mahele o Colistimethate?

Mai ka mea e hāʻawi ʻia ai ka colistimethate e nā poʻe loea mālama ola i kahi hoʻonohonoho lapaʻau, ʻaʻole pono ʻoe e hopohopo e pili ana i ka hala ʻana i nā mahele. E hōʻoia kāu hui lapaʻau e loaʻa iā ʻoe kāu lāʻau lapaʻau ma ka papa manawa ma ke ʻano he ʻāpana o kāu hoʻolālā lapaʻau.

Inā no kekahi kumu i hoʻopaneʻe ʻia kahi lāʻau lapaʻau ma muli o nā kaʻina hana lapaʻau a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe, e hoʻoponopono kāu hui mālama ola i ka manawa kūpono. E hōʻoia lākou e loaʻa iā ʻoe ka papa piha o ka lāʻau lapaʻau e pono ai no kāu maʻi.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Colistimethate?

ʻAʻole pono ʻoe e hooki i ka lāʻau lapaʻau colistimethate ma kāu iho - pono e hana mau ʻia kēia hoʻoholo e kāu hui mālama ola e pili ana i kāu pane ʻana i ka lāʻau lapaʻau a me nā hopena hoʻāʻo. ʻO ka hooki ʻana i ka wā mua e hiki ai i ka maʻi ke hoʻi mai ikaika ma mua.

E hoʻoholo kāu kauka i ka manawa e hooki ai i ka lāʻau lapaʻau e pili ana i kekahi mau mea: e hoʻomaikaʻi ana kāu mau hōʻailona, ​​e hōʻike ana nā hoʻāʻo koko e hoʻomaʻemaʻe ana ka maʻi, a me ka hōʻoia ʻana ua loaʻa iā ʻoe ka lāʻau lapaʻau lawa e pale ai i ka bacteria mai ka hoʻi ʻana mai.

Hiki iā Colistimethate ke launa pū me nā lāʻau lapaʻau ʻē aʻe?

ʻAe, hiki i ka colistimethate ke launa pū me kekahi mau lāʻau lapaʻau ʻē aʻe, ʻo ia ke kumu e nānā ai kāu hui lapaʻau i kāu mau lāʻau lapaʻau i kēia manawa ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau. ʻO nā pilina koʻikoʻi loa me nā lāʻau lapaʻau ʻē aʻe e hiki ke hoʻopilikia i nā puʻupaʻa a i ʻole ka ʻōnaehana nerve.

ʻO nā lāʻau lapaʻau e like me nā lāʻau antibiotic aminoglycoside, kekahi mau diuretics, a me kekahi mau lāʻau ʻeha e hiki ke hoʻonui i ka pilikia o nā pilikia o ka puʻupaʻa ke hui pū ʻia me colistimethate. E mālama pono kāu hui mālama ola i kēia mau pilina a hiki ke hoʻoponopono i nā lāʻau lapaʻau a i ʻole ka manawa o nā lāʻau lapaʻau ʻē aʻe e like me ka mea e pono ai.