Eculizumab-aeeb (alaloa intravenous)

Bkemv

Hoʻohana ʻia ka inikini Eculizumab-aeeb e mālama i kekahi ʻano o ka maʻi koko i kapa ʻia ʻo ka paroxysmal nocturnal hemoglobinuria (PNH). Kōkua kēia lāʻau lapaʻau e hoʻemi i ka luku ʻana a i ʻole ka haki ʻana o nā pūnaewele koko ʻulaʻula (hemolysis) i nā mea maʻi me ka PNH. Hoʻohana pū ʻia kēia lāʻau lapaʻau e mālama i kahi maʻi ʻōpū koʻikoʻi i kapa ʻia ʻo atypical hemolytic uremic syndrome (aHUS). He monoclonal antibody ka inikini Eculizumab-aeeb e hana ana ma ka ʻōnaehana pale. Loaʻa wale kēia lāʻau lapaʻau ma lalo o kahi papahana hoʻolaha palena i kapa ʻia ʻo BKEMV™ REMS (Risk Evaluation and Mitigation Strategy) Program.

I ka hoʻoholo ʻana e hoʻohana i kahi lāʻau lapaʻau, pono e kaulike ke kaumaha o ka lawe ʻana i ka lāʻau lapaʻau me ka pono e hana ai. He hoʻoholo kēia āu a me kāu kauka e hana ai. No kēia lāʻau lapaʻau, pono e noʻonoʻo i kēia mau mea: E haʻi aku i kāu kauka inā ua loaʻa iā ʻoe kekahi hopena maʻamau ʻole a i ʻole nā ​​hopena ʻē aʻe i kēia lāʻau lapaʻau a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe. E haʻi aku pū i kāu limahana mālama ola inā loaʻa iā ʻoe nā ʻano ʻē aʻe o nā mea ʻē aʻe, e like me nā meaʻai, nā mea kala, nā mea mālama, a i ʻole nā ​​holoholona. No nā huahana kūʻai ʻole ʻia, e heluhelu pono i ka lepili a i ʻole nā ​​mea hoʻohui pūʻolo. ʻAʻohe mau haʻawina kūpono i hana ʻia ma ka pilina o ka makahiki i nā hopena o ka inikini eculizumab-aeeb e mālama i ka PNH i nā keiki. ʻAʻohe palekana a me ka pono i hoʻokumu ʻia. ʻAʻohe mau haʻawina kūpono i hana ʻia a hiki i kēia lā i hōʻike i nā pilikia kūikawā o nā keiki e kaupalena i ka pono o ka inikini eculizumab-aeeb e mālama i ka aHUS i nā keiki. Ua hoʻokumu ʻia ka palekana a me ka pono. ʻAʻohe mau haʻawina kūpono i hana ʻia a hiki i kēia lā i hōʻike i nā pilikia kūikawā o nā ʻelemakule e kaupalena i ka pono o ka inikini eculizumab-aeeb i nā ʻelemakule. ʻAʻohe mau haʻawina lawa i nā wāhine no ka hoʻoholo ʻana i ka pilikia o ka pēpē i ka wā e hoʻohana ana i kēia lāʻau lapaʻau i ka wā hānai. E kaulike i nā pono hiki ke loaʻa me nā pilikia hiki ke loaʻa ma mua o ka lawe ʻana i kēia lāʻau lapaʻau i ka wā hānai. ʻOiai ʻaʻole pono e hoʻohana pū ʻia kekahi mau lāʻau lapaʻau, i nā hihia ʻē aʻe, hiki ke hoʻohana pū ʻia ʻelua mau lāʻau lapaʻau ʻokoʻa ʻoiai inā hiki ke loaʻa kahi pilina. I kēia mau hihia, makemake paha kāu kauka e hoʻololi i ka nui, a i ʻole nā ​​ʻano palekana ʻē aʻe paha e pono ai. I ka wā e loaʻa ai iā ʻoe kēia lāʻau lapaʻau, he mea nui loa ia i kāu limahana mālama ola e ʻike inā ke lawe nei ʻoe i kekahi o nā lāʻau lapaʻau i helu ʻia ma lalo nei. Ua koho ʻia nā pilina aʻe ma muli o ko lākou koʻikoʻi hiki ke loaʻa a ʻaʻole pono nā mea āpau. ʻO ka hoʻohana ʻana i kēia lāʻau lapaʻau me kekahi o nā lāʻau lapaʻau aʻe ʻaʻole i ʻōlelo ʻia, akā hiki ke koi ʻia i kekahi mau hihia. Inā kuhikuhi ʻia nā lāʻau lapaʻau ʻelua, hiki i kāu kauka ke hoʻololi i ka nui a i ʻole ka pinepine o kāu hoʻohana ʻana i hoʻokahi a i ʻole nā ​​lāʻau lapaʻau ʻelua. ʻAʻole pono e hoʻohana ʻia kekahi mau lāʻau lapaʻau i ka wā a i ʻole kokoke i ka wā e ʻai ai i ka meaʻai a i ʻole ka ʻai ʻana i kekahi mau ʻano meaʻai ʻoiai hiki ke loaʻa nā pilina. ʻO ka hoʻohana ʻana i ka waiʻona a i ʻole ka paka me kekahi mau lāʻau lapaʻau hiki ke hana i nā pilina. E kūkākūkā me kāu limahana mālama ola i ka hoʻohana ʻana i kāu lāʻau lapaʻau me ka meaʻai, ka waiʻona, a i ʻole ka paka. Hiki i ka loaʻa ʻana o nā pilikia olakino ʻē aʻe ke hoʻopilikia i ka hoʻohana ʻana i kēia lāʻau lapaʻau. E hōʻoia e haʻi aku i kāu kauka inā loaʻa iā ʻoe nā pilikia olakino ʻē aʻe, ʻoiai: