He aha ka Exemestane: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ka Exemestane e kōkua i ka mālama ʻana i kekahi mau ʻano maʻi maʻi umauma i nā wahine i hala i ka menopause. No ka pūʻulu o nā lāʻau lapaʻau i kapa ʻia he aromatase inhibitors, e hana ana ma ka pale ʻana i ka hana ʻana o ka estrogen i loko o kou kino. He mea nui kēia lāʻau lapaʻau i ka pale ʻana i nā pūnaewele maʻi maʻi mai ka ulu ʻana a me ka laha ʻana ke hoʻoulu ka estrogen i ko lākou ulu.

He aha ka Exemestane?

He lāʻau lapaʻau waha ka Exemestane i hele mai i ke ʻano papa a lawe ʻia e ka waha i hoʻokahi manawa i ka lā. Ua hoʻolālā ʻia no nā wahine postmenopausal me ka maʻi maʻi umauma hormone receptor-positive. Hana ka lāʻau lapaʻau ma ka pale mau ʻana i kahi enzyme i kapa ʻia ʻo aromatase, a kou kino e hoʻohana ai e hana i ka estrogen ma hope o ka menopause.

Ua manaʻo ʻia kēia lāʻau lapaʻau he lāʻau lapaʻau i manaʻo ʻia no ka mea e manaʻo pono ana i nā ala hormone e hoʻoulu ai i kekahi mau maʻi maʻi umauma. ʻAʻole like me ka chemotherapy e pili ana i nā pūnaewele e mahele wikiwiki ana, e kālele ana ka exemestane i ka hoʻemi ʻana i nā pae estrogen i loko o kou kino. E kauoha maʻamau kāu kauka i kēia lāʻau lapaʻau ma ke ʻano he ʻāpana o kahi hoʻolālā lapaʻau piha e komo pū ana i nā lāʻau lapaʻau ʻē aʻe.

No ke aha e hoʻohana ʻia ai ka Exemestane?

Hoʻohana nui ʻia ka Exemestane e mālama i ka maʻi maʻi umauma hormone receptor-positive i nā wahine postmenopausal. Hiki i kāu kauka ke kauoha iā ia i nā kūlana like ʻole e pili ana i kāu ʻano maʻi maʻi a me ka mōʻaukala lapaʻau.

ʻO ka hoʻohana maʻamau ʻo ia ka adjuvant therapy, ʻo ia hoʻi, hāʻawi ʻia ma hope o nā lāʻau lapaʻau mua e like me ke ʻoki a i ʻole ka chemotherapy e hōʻemi i ka pilikia o ka hoʻi ʻana mai o ka maʻi maʻi. Hiki ke hoʻohana ʻia ma ke ʻano he lapaʻau laina mua no ka maʻi maʻi umauma holomua a i ʻole metastatic i laha i nā ʻāpana ʻē aʻe o kou kino.

I kekahi manawa, kuhikuhi nā kauka i ka exemestane no nā wahine i holomua kā lākou maʻi ma muli o ka mālama ʻana me kekahi lāʻau hormone i kapa ʻia ʻo tamoxifen. I kēia mau hihia, hiki i ka hoʻololi ʻana i ka exemestane ke kōkua i ka mālama ʻana i ka maʻi ke pau ka hana ʻana o ka lāʻau mua. E hoʻoholo kāu oncologist i ka manawa kūpono a me ke ala e kūpono i kāu kūlana.

Pehea e Hana ai ka Exemestane?

Hana ka Exemestane ma ka pale mau ʻana i ka enzyme aromatase, nona ke kuleana no ka hoʻololi ʻana i nā hormones ʻē aʻe i estrogen i loko o kou kino. He mea nui kēia hana ma hope o ka menopause i ka wā e pau ai nā ovaries i ka hana ʻana i ka estrogen.

Ke lawe ʻoe i ka exemestane, pili ia i ka enzyme aromatase a hoʻopau loa iā ia. Hoʻemi nui kēia i ka nui o ka estrogen e holo ana i loko o kou kino, he mea nui ia no ka mea he nui nā maʻi maʻi umauma e hilinaʻi ana i ka estrogen e ulu a hoʻonui. Ma ka ʻoki ʻana i kēia lako hormone, kōkua ka lāʻau i ka pōloli ʻana i nā cell maʻi i ka mea e pono ai lākou e ola.

Ua manaʻo ʻia kēia lāʻau lapaʻau he mea ikaika loa i kona hiki ke hōʻemi i nā pae estrogen. Hōʻike nā haʻawina e hiki i ka exemestane ke hoʻohaʻahaʻa i nā pae estrogen e 85-95% i nā wahine postmenopausal. He lōʻihi ka hopena no ka mea he mau loa ka pale ʻana o ka enzyme, ʻoiai e hana ana kou kino i nā enzyme aromatase hou i ka manawa.

Pehea e Lawe ai au i ka Exemestane?

Pono e lawe ʻia ka Exemestane i hoʻokahi manawa i ka lā ma hope o ka ʻai ʻana, ʻoi aku ka maikaʻi i ka manawa like i kēlā me kēia lā. ʻO ka lawe ʻana me ka meaʻai e kōkua i kou kino e komo i ka lāʻau lapaʻau me ka maikaʻi a hiki ke hōʻemi i ka pilikia o ka ʻōpū.

Hiki iā ʻoe ke lawe i ka exemestane me kekahi meaʻai, akā nui ka poʻe i ʻike he mea maʻalahi ke lawe ma hope o ka ʻaina kakahiaka a i ʻole ka ʻaina ahiahi. Pono e ale ʻia ka papa holoʻokoʻa me ka wai a ʻaʻole pono e ʻoki ʻia, wāwahi ʻia, a nau ʻia. Inā pilikia ʻoe i ka ale ʻana i nā papa, e kamaʻilio me kāu kauka e pili ana i nā koho ʻē aʻe.

He mea nui e hoʻokumu i kahi hana maʻamau e hana ana no ʻoe, no ka mea, kōkua ka hoʻomau ʻana i ka mālama ʻana i nā pae paʻa o ka lāʻau lapaʻau i loko o kou kino. Hoʻonohonoho kekahi poʻe i ka uaki ala i kēlā me kēia lā a i ʻole e mālama i kā lākou ʻōmole lāʻau lapaʻau ma kahi kokoke i kā lākou pulupulu niho i mea hoʻomanaʻo. Mai hopohopo inā lawe ʻoe ia me kahi mea ʻai māmā ma kahi o ka ʻai piha, inā ʻoe e ʻai ana i kekahi mea.

Pehea ka lōʻihi e lawe ai au i ka Exemestane?

ʻO ka lōʻihi maʻamau o ka mālama ʻana i ka exemestane e ʻokoʻa ana ma muli o kāu kūlana kikoʻī, akā nui nā wahine e lawe iā ia no ʻelima mau makahiki. E hoʻoholo kāu oncologist i ka lōʻihi kūpono o ka mālama ʻana ma muli o kāu ʻano maʻi maʻi, ke kahua, a me ka pane ʻana i ka lāʻau lapaʻau.

No ka lāʻau lapaʻau adjuvant ma hope o ka mālama mua ʻana, ʻo ka ʻōlelo paipai maʻamau he ʻelima mau makahiki o ka hormone therapy. Hiki paha kēia i ʻelima mau makahiki o ka exemestane wale nō, a i ʻole he hui pū ʻana kahi e lawe ai ʻoe i ka tamoxifen no kekahi mau makahiki a laila exemestane. Hiki i kekahi mau wahine ke pōmaikaʻi mai ka mālama ʻana i hoʻonui ʻia ma mua o ʻelima mau makahiki.

E nānā mau kāu kauka i kāu pane ʻana i ka lāʻau lapaʻau a hiki ke hoʻoponopono i ka lōʻihi ma muli o ka maikaʻi o kou ʻae ʻana i ka lāʻau lapaʻau a me ke ʻano o kāu maʻi maʻi. Mai hooki i ka lawe ʻana i ka exemestane me ka kūkākūkā ʻole ʻana me kāu hui mālama ola mua, ʻoiai inā maikaʻi ʻoe a i ʻole e ʻike ana i nā hopena ʻaoʻao.

He aha nā hopena ʻaoʻao o Exemestane?

E like me nā lāʻau lapaʻau a pau, hiki i ka exemestane ke hoʻoulu i nā hopena ʻaoʻao, ʻoiai ʻaʻole ʻike nā mea a pau iā lākou. ʻO ka hapa nui o nā hopena ʻaoʻao e pili ana i ka hopena o ka lāʻau lapaʻau o ka hoʻohaʻahaʻa ʻana i nā pae estrogen i loko o kou kino.

ʻO nā hopena ʻaoʻao maʻamau i ʻike ʻia e nā wahine he wela wela, ʻeha hui a me ka ʻoʻoleʻo, luhi, a me ke poʻo. Hiki ke mālama pinepine ʻia kēia mau hōʻailona a hiki ke hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau i nā mahina mua o ka mālama ʻana.

Eia nā hopena ʻaoʻao āu e hālāwai ai, i hoʻonohonoho ʻia mai ka mea maʻamau i ka mea maʻamau:

• Nā ʻāhuʻu wela a me nā pō ʻāhuʻu
• ʻEha hui, paʻakikī, a i ʻole nā ʻeha ʻiʻo
• Luhi a me ka nāwaliwali
• ʻEha poʻo
• ʻO ka nausea a i ʻole ka ʻōpū
• He paʻakikī ka hiamoe
• Nā loli o ka naʻau a i ʻole ke kaumaha
• Hoʻonui i ka hou
• ʻĀwili
• Nalo o ka ʻai

ʻAʻole maʻamau akā ʻoi aku ka hopena ʻino e komo pū ana me ka lahilahi o nā iwi (osteoporosis), ka hoʻonui ʻia o ka pilikia o nā haʻi, a me nā hopena cardiovascular. Hiki i kekahi mau wahine ke ʻike i ka lahilahi o ka lauoho, nā loli o ka ʻili, a i ʻole ka hoʻonui ʻia o nā pae cholesterol. Hoʻomohala mālie kēia mau hopena a pono e nānā ʻia e kāu hui mālama ola.

ʻO nā hopena ʻaoʻao maʻamau akā koʻikoʻi e komo pū ana me nā hopena maʻi maʻi koʻikoʻi, nā pilikia o ke ake, a i ʻole nā loli nui i nā helu koko. E kelepona koke i kāu kauka inā ʻike ʻoe i ka ʻeha nui o ka ʻōpū, ka melemele o ka ʻili a i ʻole nā maka, ka ʻeha a i ʻole ke kahe ʻana o ke koko, a i ʻole nā hōʻailona o ka maʻi e like me ke kuni mau.

ʻO wai ka mea ʻaʻole pono e lawe iā Exemestane?

ʻAʻole kūpono ʻo Exemestane no nā mea a pau, a ʻo kekahi mau maʻi olakino a i ʻole nā kūlana e kūpono ʻole ai a i ʻole ka weliweli. E nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana i kēia lāʻau.

ʻAʻole pono nā wahine premenopausal e lawe iā exemestane no ka mea he pono wale nō ma hope o ka menopause i ka wā i hoʻololi ʻia ai ka hana estrogen i nā ʻiʻo peripheral. ʻAʻole pono nā wahine hāpai a i ʻole e hānai ana i ka waiū e lawe i kēia lāʻau no ka mea hiki ke hōʻino i ka pēpē e ulu ana.

ʻAʻole hiki i ka poʻe me ka maʻi ate koʻikoʻi ke hana palekana iā exemestane, a pono paha ka poʻe me kekahi mau pilikia o ka puʻupaʻa i nā hoʻoponopono dosage. Inā he mōʻaukala kou o ka osteoporosis koʻikoʻi a i ʻole nā haʻi pinepine, pono kāu kauka e kaupaona pono i nā pōmaikaʻi e kūʻē i nā pilikia.

Pono ʻoe e haʻi i kāu kauka inā he mōʻaukala kou o nā ʻōpū koko, maʻi puʻuwai, cholesterol kiʻekiʻe, a i ʻole ke kaumaha. ʻOiai ʻaʻole pono kēia mau maʻi e pale i ka hoʻohana ʻana i ka exemestane, pono lākou i ka nānā pono ʻana a me nā lāʻau lapaʻau hou e mālama i nā pilikia.

Nā inoa inoa o Exemestane

Loaʻa ʻo Exemestane ma lalo o nā inoa inoa like ʻole, ʻo Aromasin ka mea i ʻike nui ʻia. ʻO kēia lāʻau lapaʻau inoa inoa ka mea i hoʻomohala mua ʻia a ke kauoha nui ʻia nei e nā oncologists.

Loaʻa nō hoʻi nā mana generic o exemestane a loaʻa iā lākou ka mea hana like me ka mana inoa inoa. Hana ʻia kēia mau lāʻau lapaʻau generic i nā hoʻokolohua koʻikoʻi e hōʻoia i ka hana ʻana e like me ka maikaʻi o Aromasin. Hiki i kāu ʻinikua ke makemake i ka mana generic, hiki ke kōkua i ka hōʻemi ʻana i kāu mau kumukūʻai mai ka ʻeke.

Inā loaʻa iā ʻoe ka inoa inoa Aromasin a i ʻole ka exemestane generic, e mau ana ka pono a me ka palekana o ka lāʻau lapaʻau. Hiki i kāu kauka lāʻau ke pane i nā nīnau e pili ana i ka mana āu e loaʻa nei a kōkua iā ʻoe e hoʻomaopopo i nā ʻokoʻa i ke ʻano ma waena o nā mea hana.

Nā koho ʻē aʻe o Exemestane

Nui nā lāʻau lapaʻau ʻē aʻe e hiki ke lilo i mea ʻē aʻe i ka exemestane, ma muli o kāu kūlana olakino. ʻO ke koho ma waena o nā lāʻau lapaʻau hormone like ʻole e hilinaʻi ana i nā mea e like me kāu mōʻaukala lapaʻau, ka ʻae ʻana i ka hopena ʻaoʻao, a me nā ʻano maʻi maʻi.

ʻO nā mea pale aromatase ʻē aʻe e pili ana i ka anastrozole (Arimidex) a me letrozole (Femara), e hana like me exemestane akā he ʻokoʻa iki nā ʻaoʻao hopena. ʻO kekahi mau wahine e ʻae maikaʻi i kekahi mea pale aromatase ma mua o kekahi, no laila he mea maikaʻi ke hoʻololi ma waena o lākou.

He hōʻailona ʻo Tamoxifen i kahi ʻano ʻokoʻa o ka lāʻau hormone e hana ana ma ka pale ʻana i nā mea hoʻokipa estrogen ma mua o ka hoʻemi ʻana i ka hana estrogen. He koho paha kēia lāʻau lapaʻau inā ʻaʻole hiki iā ʻoe ke ʻae i nā mea pale aromatase a i ʻole inā manaʻo kāu kauka he kūpono ia no kou kūlana.

Hiki ke noʻonoʻo ʻia nā lāʻau lapaʻau hou e like me fulvestrant (Faslodex) a i ʻole CDK4/6 inhibitors i hui pū ʻia me ka lāʻau hormone i nā kūlana kikoʻī, ʻoi aku hoʻi no ka maʻi maʻi umauma holomua. E kōkua kāu oncologist e hoʻoholo i ke ala e hāʻawi ai i ke kaulike maikaʻi loa o ka pono a me ka ʻae ʻana iā ʻoe.

Ua ʻoi aku ka maikaʻi o Exemestane ma mua o Anastrozole?

He mea pono nā mea pale aromatase ʻo Exemestane a me anastrozole, akā hana lākou i nā mea ʻokoʻa iki a loaʻa paha nā ʻano hopena ʻaoʻao like ʻole. Ua kapa ʻia ʻo Exemestane he

Hiki ke hoʻohana ʻia ʻo Exemestane i nā wahine me ka maʻi puʻuwai, akā pono ka nānā pono ʻana a me ka hui pū ʻana me kāu cardiologist. Hiki i ka lāʻau lapaʻau ke hoʻopilikia i nā pae cholesterol a loaʻa paha nā hopena cardiovascular ʻē aʻe ma muli o ka hoʻopaʻa ʻana i ka estrogen.

E nānā paha kāu kauka i ke olakino o kou puʻuwai i ka wā e lawe ana ʻoe i ka exemestane, me nā hoʻokolohua koko maʻamau e nānā i ka cholesterol a me nā mea pilikia cardiac ʻē aʻe. Pono paha kekahi mau wahine i nā lāʻau lapaʻau hou e mālama i kēia mau hopena, e like me nā statins no ka mālama cholesterol.

ʻO ka hoʻoholo e hoʻohana i ka exemestane me ka maʻi puʻuwai e hilinaʻi ana i ka hoʻohālikelike ʻana i nā pōmaikaʻi o ka mālama ʻana i ka maʻi maʻi me nā pilikia cardiovascular. E hana pū kāu oncologist a me ka cardiologist e hana i kahi hoʻolālā nānā e mālama ana i kāu maʻi maʻi a me ke olakino o ka puʻuwai.

He aha kaʻu e hana ai inā ua hoʻohana hewa au i ka nui o Exemestane?

Inā ua lawe hewa ʻoe ma mua o kāu mahele i kuhikuhi ʻia o ka exemestane, e kelepona koke i kāu kauka a i ʻole ke kikowaena mana ʻawaʻawa. Mai kali e ʻike inā e ulu nā hōʻailona, ​​no ka mea, ʻo ka loaʻa ʻana o ka ʻōlelo aʻoaʻo lapaʻau wikiwiki ʻo ia ke ala palekana loa.

ʻO ka lawe ʻana i ka nui o ka exemestane hiki ke hoʻoulu i nā hopena ʻaoʻao ʻoi aku ka nui e like me ka luhi nui, ka nausea nui, a i ʻole nā ​​hōʻailona ʻē aʻe e pili ana i nā pae estrogen haʻahaʻa loa. Hiki i nā poʻe loea lapaʻau ke aʻo iā ʻoe i ka mea e nānā ai a inā pono ʻoe i ka lāʻau lapaʻau koke.

E lawe mai i ka hue lāʻau me ʻoe inā pono ʻoe e ʻimi i ka mālama olakino, no ka mea, kōkua kēia i nā mea mālama ola e hoʻomaopopo pono i ka mea a me ka nui āu i lawe ai. Mai ho'āʻo e

Inā kokoke ka manawa no kāu mahele lāʻau e hiki mai ana (i loko o 12 hola), e lele i ka mahele lāʻau i hala a e hoʻomau me kāu papa maʻamau. ʻO ka lawe ʻana i ʻelua mahele lāʻau kokoke loa i kekahi i kekahi hiki ke hoʻonui i kou pilikia o nā hopena ʻaoʻao me ka ʻole o ka hāʻawi ʻana i ka pōmaikaʻi hou.

E hoʻāʻo e hoʻokumu i nā hana maʻamau e kōkua iā ʻoe e hoʻomanaʻo i kāu mahele lāʻau i kēlā me kēia lā, e like me ka hoʻonohonoho ʻana i nā ʻōhua kelepona a i ʻole ka hoʻohana ʻana i nā mea hoʻonohonoho pila. Inā poina pinepine ʻoe i nā mahele lāʻau, e kūkākūkā i nā hoʻolālā me kāu hui mālama ola e hoʻomaikaʻi i ke kūlike, no ka mea, he mea nui ka hoʻopaʻa ʻana i kēlā me kēia lā no ka mālama ʻana i ka maʻi maʻi.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Exemestane?

Pono ʻoe e hooki i ka lawe ʻana iā exemestane ke hoʻoholo kāu oncologist he kūpono, ʻoiai inā maikaʻi ʻoe a i ʻole e ʻike ana i nā hopena ʻaoʻao. ʻO ka hoʻoholo e hooki i ka mālama ʻana e pili ana i nā mea he nui me ke ʻano o kāu maʻi maʻi, ka pane ʻana i ka mālama ʻana, a me ke kūlana olakino holoʻokoʻa.

Lawe ka hapa nui o nā wahine iā exemestane no kahi o ʻelima mau makahiki, akā pono paha kekahi i ka mālama ʻana i ka lōʻihi a i ʻole hiki ke hooki koke ʻia ma muli o ko lākou kūlana pilikino. E loiloi mau kāu kauka inā hāʻawi ka mālama ʻana i ka pōmaikaʻi hou aʻe ma mua o ka pilikia.

Inā paʻakikī nā hopena ʻaoʻao e hoʻomau i ka mālama ʻana, e kūkākūkā i kēia me kāu hui mālama ola ma mua o ka hooki ʻana iā ʻoe iho. ʻO ka pinepine, aia nā ala e mālama ai i nā hopena ʻaoʻao a i ʻole e hoʻoponopono i ka mālama ʻana e hiki ai iā ʻoe ke hoʻomau i ka loaʻa ʻana o nā pōmaikaʻi hakakā maʻi maʻi o ka lāʻau.

Hiki iaʻu ke lawe iā Exemestane me nā lāʻau ʻē aʻe?

Hiki iā Exemestane ke launa pū me kekahi mau lāʻau, no laila he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau, nā lāʻau lapaʻau ma luna o ka pāʻani, a me nā mea hoʻohui āu e lawe nei. Hiki i kekahi mau lāʻau lapaʻau ke hoʻopilikia i ka maikaʻi o ka hana ʻana o exemestane a i ʻole e hoʻonui i ka pilikia o nā hopena ʻaoʻao.

Hiki i nā lāʻau lapaʻau i loaʻa ka estrogen e like me ka hormone replacement therapy a i ʻole nā pila hānau ke hōʻole i nā hopena o ka exemestane a pono e pale ʻia. Hiki i kekahi mau mea hoʻohui lāʻau lapaʻau, ʻo ia hoʻi nā mea me nā hopena estrogen-like, ke keakea i ka mālama ʻana.

Hiki i kāu kauka a me ka lāʻau lapaʻau ke kōkua iā ʻoe e hoʻomaopopo i nā lāʻau lapaʻau e palekana ai ke lawe me ka exemestane a me nā mea e pale ai. E nānā mau ma mua o ka hoʻomaka ʻana i nā lāʻau lapaʻau hou a i ʻole nā mea hoʻohui, ʻoiai nā mea i ʻike ʻole ʻia e pili ana i kāu mālama ʻana i ka maʻi kanesa.