He aha ʻo Fosaprepitant: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau ʻo Fosaprepitant i hāʻawi ʻia ma o ka laina IV (intravenous) e kōkua i ka pale ʻana i ka nausea a me ka luaʻi ʻana, ʻoi aku hoʻi ke loaʻa nei ʻoe i ka chemotherapy a i ʻole ke hana ʻana i ke ʻoki. He ʻano wai ia o ka aprepitant e hana ana ma ka pale ʻana i kekahi mau mea loaʻa i loko o kou lolo e hoʻoulu ai i kēia mau manaʻo ʻoluʻolu ʻole.

No ka papa o nā mea i kapa ʻia ʻo NK1 receptor antagonists kēia lāʻau lapaʻau. E noʻonoʻo iā ia e like me ka waiho ʻana i kahi pale mālie i loko o kou lolo e kūʻē i nā hōʻailona e maʻi ai ʻoe i kou ʻōpū.

He aha ʻo Fosaprepitant?

He prodrug ʻo Fosaprepitant, ʻo ia hoʻi, hoʻololi ia i ka lāʻau lapaʻau ikaika (aprepitant) ke komo i loko o kou kino. Ua hoʻolālā ʻia e hāʻawi ʻia ma o ka IV ke hiki ʻole iā ʻoe ke lawe i nā pila ma ka waha a i ʻole ke pono nā kauka i ka lāʻau e hana wikiwiki.

Hāʻawi ke ʻano IV i nā mea mālama ola e hāʻawi i ka lāʻau lapaʻau pololei i loko o kou kahe koko. Hiki ke kōkua nui kēia ke maʻi ʻoe a i ʻole ke pono ʻoe i ka pale koke ma mua o ke kaʻina hana lapaʻau.

ʻAʻole like me kekahi mau lāʻau anti-nausea e hana ana i kou ʻōpū, hana ʻo fosaprepitant i ke kikowaena luaʻi o kou lolo. ʻO kēia ala i manaʻo ʻia e hana pono ai no ka nausea i hoʻokumu ʻia e ka chemotherapy, ʻaʻole pinepine e pane maikaʻi i nā lāʻau lapaʻau ʻē aʻe.

No ke aha e hoʻohana ʻia ai ʻo Fosaprepitant?

Hoʻohana nui ʻia ʻo Fosaprepitant e pale i ka nausea a me ka luaʻi ʻana i hana ʻia e nā lāʻau chemotherapy. He mea maikaʻi loa ia e kūʻē i ka mea a nā kauka e kapa ai he

Hoʻohana maʻamau ʻia ka lāʻau lapaʻau ma ke ʻano he ʻāpana o kahi ala hui pū. Eia ka manawa e ʻōlelo ai nā kauka:

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• Ma mua o ka loaʻa ʻana o nā lāʻau chemotherapy ikaika e like me cisplatin a i ʻole cyclophosphamide
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• Ma ke ʻano he ʻāpana o kahi papa lāʻau ʻekolu me nā lāʻau anti-nausea ʻē aʻe
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• Inā loaʻa iā ʻoe ka nausea koʻikoʻi me nā lāʻau lapaʻau mua
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• Ma mua o nā ʻoki nui kahi e hiki ai ka nausea ma hope o ka hana
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• Ke ʻaʻole kūpono a maikaʻi ʻole nā lāʻau lapaʻau waha
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He mea pono e hoʻomaopopo i ka hana maikaʻi loa ʻana o ka fosaprepitant ke hoʻohana ʻia i ka pale ʻana ma mua o ka mālama ʻana i ka nausea i hoʻomaka mua. ʻO kēia ke kumu e hāʻawi maʻamau ai nā kauka iā ia ma mua o ka hoʻomaka ʻana o kāu chemotherapy a i ʻole ke ʻoki.

Pehea e hana ai ʻo Fosaprepitant?

Hana ʻo Fosaprepitant ma ka pale ʻana i nā mea loaʻa NK1 i loko o ke kikowaena luaʻi o kou lolo. Hoʻopili maʻamau kēia mau mea loaʻa i kahi kemika i kapa ʻia ʻo ka mea P, e hoʻoulu ai i ka nausea a me ka luaʻi ʻana i ka wā e hoʻokuʻu ʻia ai i ka wā chemotherapy a i ʻole ke koʻikoʻi.

Ke komo ka lāʻau lapaʻau i loko o kou kahe koko, hoʻololi koke ia i aprepitant, ke ʻano hana. A laila hele kēia lāʻau lapaʻau hana i kou lolo a

Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano he infusion lohi ma luna o 20-30 mau minuke. E nānā pono kāu kahu hānai i ka helu infusion e hōʻoia i kou ʻoluʻolu a ʻaʻole ʻoe e ʻike i nā hopena ʻino.

ʻAʻole pono ʻoe e hoʻokē ʻai ma mua o ka loaʻa ʻana o ka fosaprepitant, a hiki iā ʻoe ke ʻai maʻamau ke ʻole i hāʻawi kāu kauka iā ʻoe i nā ʻōlelo aʻo ʻē aʻe e pili ana i kāu chemotherapy a i ʻole ke ʻoki. ʻO ka ʻai ʻana i kahi meaʻai māmā ma mua e kōkua maoli nō ia iā ʻoe e ʻoluʻolu.

Eia ka mea e manaʻo ai i ka wā o kāu infusion:

1. E hoʻomaka kāu kahu hānai i kahi laina IV inā ʻaʻohe ou
2. E hui pū ʻia ka lāʻau lapaʻau me ka hopena saline
3. E holo mālie ka infusion ma luna o 20-30 mau minuke
4. E nānā ʻia ʻoe no nā hopena i ka wā a ma hope o ka infusion
5. Hiki iā ʻoe ke hoʻomau i nā hana maʻamau ma hope koke iho

He mea nui e noho hydrated ma mua a ma hope o kāu infusion. ʻO ka inu ʻana i ka wai nui hiki ke kōkua i kou kino e hana i ka lāʻau lapaʻau ʻoi aku ka maikaʻi a hiki ke hōʻemi i ka pilikia o nā hopena ʻaoʻao.

Pehea ka lōʻihi e lawe ai au i ka Fosaprepitant?

Hāʻawi ʻia ka Fosaprepitant ma ke ʻano he hoʻokahi ma mua o ka chemotherapy a i ʻole ke ʻoki. Hiki i nā hopena o hoʻokahi maʻi ke mau no kekahi mau lā, ʻo ia ka mea maʻamau e pale i ka nausea i ka wā o kāu mālama ʻana.

No nā maʻi chemotherapy, hiki iā ʻoe ke loaʻa i ka fosaprepitant ma mua o kēlā me kēia pōʻai o ka mālama ʻana. E hoʻoholo kāu oncologist i ka papa manawa kikoʻī e pili ana i kāu regimen chemotherapy kikoʻī a me ka maikaʻi o kāu pane ʻana i ka lāʻau lapaʻau.

Aia ka lōʻihi o ka mālama ʻana i kāu kūlana olakino. Inā e hana ʻoki ana ʻoe, e loaʻa paha iā ʻoe hoʻokahi wale nō. Inā e hele ana ʻoe i nā pōʻai he nui o ka chemotherapy, hiki iā ʻoe ke loaʻa ma mua o kēlā me kēia pōʻai ma luna o kekahi mau mahina.

E nānā ana kāu hui mālama ola i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau iā ʻoe a e hoʻoponopono i ka hoʻolālā lapaʻau e like me ka mea e pono ai. Manaʻo kekahi poʻe e pono lākou i ia mea no kēlā me kēia pōʻai chemotherapy, a ʻo nā mea ʻē aʻe paha e pono ai ia mea no nā lāʻau lapaʻau mua.

He aha nā hopena ʻaoʻao o Fosaprepitant?

Hoʻomanawanui ka hapa nui o nā kānaka iā fosaprepitant, a ʻaʻole maʻamau nā hopena ʻaoʻao koʻikoʻi. ʻO nā hopena ʻaoʻao pinepine ka maʻalahi a me ka manawa.

E hoʻomaka kākou me nā hopena ʻaoʻao maʻamau āu e ʻike ai, e hoʻoponopono maʻamau iā lākou iho i loko o hoʻokahi a ʻelua paha lā:

• Luhi a i ʻole ka manaʻo luhi
• ʻEha poʻo
• Pōniuniu
• Paʻa
• Nalo o ka ʻai
• Hiccups
• ʻEha māmā a i ʻole ka huhū ma ke kahua IV

ʻAʻole pono kēia mau hopena maʻamau i ka lapaʻau a hoʻomaikaʻi pinepine i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau. Hiki i ka noho ʻana i ka wai a me ka hoʻomaha ke kōkua i ka mālama ʻana i kēia mau hōʻailona.

ʻAʻole maʻamau akā ʻoi aku ka hopohopo o nā hopena ʻaoʻao e pono ai ka lāʻau lapaʻau. ʻOiai he kakaikahi kēia, he mea nui e ʻike i ka mea e nānā ai:

• Nā hopena maʻi maʻi koʻikoʻi (ʻulaʻula, pehu, pilikia o ka hanu)
• Ka puʻuwai puʻuwai ʻole a i ʻole ka ʻeha o ka umauma
• Pōniuniu nui a i ʻole ka hāʻule
• Nā hōʻailona o nā pilikia o ke ake (melemele o ka ʻili a i ʻole nā maka, mimi ʻeleʻele)
• ʻEha ʻōpū nui
• Nā loli ʻano ʻē a i ʻole ka huikau

Hiki mai kēia mau hopena ʻaoʻao koʻikoʻi i ka liʻiliʻi ma mua o 1% o nā maʻi, akā pono lākou i ka lāʻau lapaʻau koke inā e ulu lākou.

ʻO wai ka mea ʻaʻole pono e lawe iā Fosaprepitant?

ʻAʻole kūpono ʻo Fosaprepitant no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. ʻO ka hopohopo nui pehea e launa pū ai kēia lāʻau lapaʻau me nā lāʻau ʻē aʻe āu e lawe nei.

Pono ʻoe e haʻi i kāu mea mālama ola inā he moʻolelo kou o nā hopena maʻi ʻaʻai i ka fosaprepitant a i ʻole aprepitant. ʻOiai he hopena maʻalahi i ka wā i hala e hōʻike ana ʻaʻole palekana kēia lāʻau lapaʻau iā ʻoe.

Pono ka poʻe me kekahi mau maʻi olakino i ka mālama nui a i ʻole pono e pale i ka fosaprepitant:

• Maʻi ate koʻikoʻi a i ʻole ka hāʻule ʻana o ke ake
• Nā maʻi puʻuwai
• ʻIke ʻia ka hypersensitivity i nā mea kūʻē i ka NK1 receptor
• Maʻi kīkī koʻikoʻi
• Nā maʻi koko e hana ana

Pono ka hāpai ʻana a me ka hānai ʻana i ka umauma i ka noʻonoʻo kūikawā. ʻOiai ʻaʻole i aʻo nui ʻia ka fosaprepitant i nā wahine hāpai, e kaupaona kāu kauka i nā pōmaikaʻi e kūʻē i nā pilikia hiki ke loaʻa inā ʻoe e kali ana a i ʻole e hānai ana.

Hiki i ka lāʻau lapaʻau ke launa pū me nā lāʻau lapaʻau ʻē aʻe, me nā mea hoʻokahe koko, kekahi mau antibiotics, a me kekahi mau lāʻau anti-seizure. ʻO ia ke kumu he mea nui e hāʻawi i kāu hui mālama ola i kahi papa inoa piha o nā lāʻau lapaʻau a me nā mea hoʻohui āu e lawe nei.

Nā inoa inoa Fosaprepitant

Loaʻa ka Fosaprepitant ma lalo o ka inoa inoa Emend for Injection ma ʻAmelika Hui Pū ʻIa. ʻO kēia ka inoa inoa i ʻike nui ʻia no ka formulation IV.

Hiki i nā ʻāina like ʻole ke loaʻa nā inoa inoa like ʻole no ka lāʻau lapaʻau like. Hiki i kāu kauka lāʻau a i ʻole mea mālama ola ke haʻi iā ʻoe i ka inoa kikoʻī āu e loaʻa nei.

Loaʻa pū kekahi nā mana generic o fosaprepitant, aia ka mea hana like akā hiki ke emi ke kumukūʻai. He kūpono nā mana generic e like me ka lāʻau inoa inoa.

Nā koho ʻē aʻe o Fosaprepitant

Hiki ke hoʻohana ʻia kekahi mau lāʻau anti-nausea ʻē aʻe ma kahi o a i ʻole me ka fosaprepitant. Hiki i kāu kauka ke noʻonoʻo i kēia mau koho ʻē aʻe e pili ana i kāu kūlana kikoʻī a me ka mōʻaukala olakino.

ʻO nā koho ʻē aʻe maʻamau e komo pū ana me ka ondansetron (Zofran), e hana ana ma ka pale ʻana i nā mea hoʻokipa like ʻole i kou lolo. ʻO Metoclopramide (Reglan) kekahi koho ʻē aʻe e hana ana i kou lolo a me ka ʻōnaehana digestive.

Eia nā koho nui e noʻonoʻo ai kāu kauka:

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• Ondansetron (Zofran) - pale i nā mea hoʻokipa serotonin
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• Granisetron (Kytril) - kekahi mea pale i ka mea hoʻokipa serotonin
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• Dexamethasone - he steroid e hōʻemi ana i ka mumū
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• Metoclopramide (Reglan) - kōkua i ka hakahaka o ka ʻōpū
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• Prochlorperazine (Compazine) - pale i nā mea hoʻokipa dopamine
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• Aprepitant waha (Emend capsules) - inā hiki iā ʻoe ke lawe i nā pila
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Nui nā kauka e hoʻohana i nā ala hui pū, e hui pū ana i ka fosaprepitant me nā lāʻau anti-nausea ʻē aʻe no ka pono kiʻekiʻe. ʻO kēia ala multi-drug e hana pinepine maikaʻi ma mua o kekahi lāʻau hoʻokahi wale nō.

Ua ʻoi aku ka maikaʻi o Fosaprepitant ma mua o Ondansetron?

Hana ʻokoʻa ʻo Fosaprepitant a me ondansetron a hoʻohana pinepine ʻia pū kekahi ma mua o nā koho hoʻokūkū. Hoʻopili lākou i nā ala like ʻole i ke kikowaena nausea o kou lolo, e hana ana iā lākou i mea hoʻohui ma mua o ka hoʻokūkū.

ʻOi aku ka maikaʻi o Fosaprepitant no ka nausea lohi, hiki ke hana 24-72 mau hola ma hope o ka chemotherapy. Hana maikaʻi ʻo Ondansetron no ka nausea koke e hana ana i ka wā a i ʻole ma hope koke o ka mālama ʻana.

No ka chemotherapy emetogenic kiʻekiʻe, manaʻo ʻia ʻo fosaprepitant ʻoi aku ka maikaʻi ma mua o ka ondansetron wale nō. Eia naʻe, makemake pinepine ʻia ka ondansetron no ka nausea maʻalahi a me ka maʻalahi no ka mea he liʻiliʻi nā pilina lāʻau a ʻoi aku ka liʻiliʻi.

Aia ka koho

ʻAe, palekana maʻamau ka fosaprepitant no ka poʻe me ka maʻi diabetes. ʻAʻole pili pololei ka lāʻau i nā pae kōpaʻa koko, no laila ʻaʻole pono e keakea i kāu mālama ʻana i ka maʻi diabetes.

Eia naʻe, inā e loaʻa ana iā ʻoe ka chemotherapy, hiki i ke koʻikoʻi o ka mālama ʻana a me nā loli i nā ʻano ʻai ke hoʻopilikia i kou kōpaʻa koko. He mea nui e nānā pono i kāu mau pae glucose i ka wā o ka mālama ʻana a kūkākūkā i nā hopohopo me kāu hui mālama ola.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o ka Fosaprepitant?

No ka mea, hāʻawi ʻia ka fosaprepitant e nā poʻe loea mālama ola i kahi hoʻonohonoho lapaʻau, he mea maʻamau loa ka overdose ulia pōpilikia. Hoʻohālikelike ʻia ka dosing a nānā pono ʻia i ka wā o ka lawelawe ʻana.

Inā hopohopo ʻoe no ka loaʻa ʻana o ka nui o ka lāʻau, e kamaʻilio koke me kāu kahu hānai a i ʻole kauka. Hiki iā lākou ke nānā i kāu dosing a nānā iā ʻoe no nā hōʻailona maʻamau ʻole. ʻAʻohe antidote kikoʻī no ka overdose fosaprepitant, akā hiki i ka mālama kākoʻo ke mālama i nā hōʻailona e ulu ana.

He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Fosaprepitant?

Inā hala ʻoe i kahi infusion fosaprepitant i hoʻonohonoho ʻia, e hoʻokaʻaʻike i kāu mea mālama ola i ka hiki wawe. E kōkua lākou iā ʻoe e hoʻonohonoho hou a hoʻoholo inā pono ʻoe i ka pale anti-nausea hou.

No nā maʻi chemotherapy, hiki i ka hala ʻana i ka lāʻau anti-nausea ke hōʻoluʻolu ʻole i kāu mālama ʻana. Hiki i kāu oncologist ke kuhikuhi i nā lāʻau lapaʻau ʻē aʻe e kōkua i ka pale ʻana i ka nausea a hiki iā ʻoe ke loaʻa i kāu mahele fosaprepitant.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Fosaprepitant?

Hiki iā ʻoe ke hooki i ka fosaprepitant ke hoʻoholo kāu kauka ʻaʻole pono ʻoe ia mea. Hana maʻamau kēia i ka wā e hoʻopau ai ʻoe i kāu mau mālama chemotherapy a i ʻole e ola mai ke ʻoki.

He nui ka poʻe e ʻike nei he pono ka fosaprepitant no kēlā me kēia pōʻai chemotherapy, aʻo nā mea ʻē aʻe e pono paha ia no nā lapaʻau mua. E hana pū kāu oncologist me ʻoe e hoʻoholo i ka papa manawa maikaʻi loa e pili ana i kāu pane a me ka ikaika o kāu papa lapaʻau.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o Fosaprepitant?

Hiki i ka Fosaprepitant ke hoʻoulu i ka noʻonoʻo a me ka luhi, no laila pono ʻoe e pale i ke kalaiwa ʻana ma hope koke o ka loaʻa ʻana o ka lāʻau. ʻOi aku ka maikaʻi e loaʻa i kekahi e kalaiwa iā ʻoe i ka home mai kāu manawa lapaʻau.

Manaʻo ka hapa nui o ka poʻe he maikaʻi ke kalaiwa i ka lā aʻe, akā e hoʻolohe i kou kino. Inā ʻoe e manaʻo nei i ka noʻonoʻo a i ʻole ka luhi ʻole, e kali a hiki i ka pau ʻana o kēia mau hopena ma mua o ka noho ʻana ma hope o ka huila. Pono e hele mua kou palekana a me ka palekana o nā poʻe ʻē aʻe ma ke alanui.