He aha ka Gallium-68 DOTATOC: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO ka Gallium-68 DOTATOC he mea hōʻailona radioactive kūikawā i hoʻohana ʻia i nā kiʻi lapaʻau e kōkua i nā kauka e ʻike i kekahi mau ʻano maʻi maʻi i loko o kou kino. Hana kēia mea hana kiʻi ma ka hoʻopili ʻana i nā mea hoʻokipa kikoʻī i loaʻa ma nā maʻi neuroendocrine, e ʻike ʻia lākou ma nā scans kūikawā i kapa ʻia ʻo PET scans.

E noʻonoʻo iā ia he kukui i manaʻo nui ʻia e kōkua ana i kāu hui lapaʻau e ʻike pololei i kahi e hūnā ai kekahi mau maʻi maʻi. Hāʻawi ʻia ka mea ma o ka IV a hele i loko o kou kahe koko e ʻimi a hōʻike i nā cell tumor i loaʻa nā mea hoʻokipa kikoʻī ma ko lākou ʻili.

No ke aha e hoʻohana ʻia ai ka Gallium-68 DOTATOC?

Hoʻohana nui ʻia ka Gallium-68 DOTATOC e ʻike a nānā i nā maʻi neuroendocrine (NETs). ʻO kēia mau maʻi maʻi e ulu mai nā cell e hana i nā hormones ma kou kino a pau, a hiki ke hana i nā ʻōpū like ʻole me kou pancreas, ʻōpū, māmā, a me nā wahi ʻē aʻe.

Hiki i kāu kauka ke ʻōlelo aku i kēia scan inā loaʻa iā ʻoe nā hōʻailona e hōʻike ana i kahi maʻi neuroendocrine, e like me ka ʻulaʻula ʻole, ka maʻi maʻi, a i ʻole ka ʻeha o ka ʻōpū. Kōkua ka scan e hoʻoholo i kahi kikoʻī, ka nui, a me ka laha ʻana o kēia mau maʻi, he mea nui ia no ka hoʻolālā ʻana i kāu mālama.

He mea waiwai nō hoʻi kēia hoʻokolohua kiʻi no ka nānā ʻana i ka maikaʻi o kāu mālama ʻana inā ua ʻike mua ʻia ʻoe me kahi maʻi neuroendocrine. Hiki iā ia ke hōʻike inā e emi ana nā maʻi, e ulu ana, a i ʻole ua ʻike ʻia nā mea hou.

Pehea e hana ai ka Gallium-68 DOTATOC?

Hana ka Gallium-68 DOTATOC ma ka ʻimi ʻana i nā mea hoʻokipa somatostatin, ʻo ia nā protein i loaʻa i nā kiʻekiʻe kiʻekiʻe ma ka ʻili o nā cell tumor neuroendocrine. Ke hoʻokomo ʻia i loko o kou kahe koko, ʻimi kēia mea hōʻailona a paʻa i kēia mau mea hoʻokipa kikoʻī.

He maʻi liʻiliʻi ka gallium-68 o ka hui ʻana a hoʻopuka i nā hōʻailona hiki ke ʻike ʻia e ka mea nānā PET. Hana kēia i nā kiʻi kikoʻī e hōʻike ana i kahi i hōʻiliʻili ai ka mea huli, e hōʻike ana i kahi a me ka nui o ka hana ʻana o ka maʻi maʻi i loko o kou kino.

He haʻahaʻa ka mahele o ka radiation mai kēia kaʻina hana a ua manaʻo ʻia he palekana no nā kumu diagnostic. E emi maoli ana ka radioactivity i ka manawa a e hoʻopau ʻia mai kou kino ma o nā kaʻina hana maʻamau i loko o kekahi mau hola.

Pehea wau e hoʻomākaukau ai no Gallium-68 DOTATOC?

Pono ʻoe e hooki i ka lawe ʻana i kekahi mau lāʻau ma mua o kāu scan, ʻo ia hoʻi nā analog somatostatin e like me octreotide a i ʻole lanreotide. E hāʻawi kāu kauka iā ʻoe i nā ʻōlelo kikoʻī e pili ana i ka manawa e hooki ai i kēia mau lāʻau, maʻamau 4-6 pule ma mua o ke kaʻina hana.

I ka lā o kāu scan, pono ʻoe e ʻai i ka ʻai māmā a e noho maikaʻi i ka wai ma ka inu ʻana i ka wai nui. ʻAʻohe palena meaʻai kikoʻī, akā ʻo ka pale ʻana i nā meaʻai nui ma mua o ke kaʻina hana hiki ke kōkua i ka hōʻoia ʻana i ka maikaʻi o ke kiʻi.

E ʻaʻahu i nā lole ʻoluʻolu, kūpono ʻole me nā mea metala e like me nā zippers, nā pihi, a i ʻole nā mea nani. Hiki ke noi ʻia ʻoe e hoʻololi i ka ʻaʻahu haukapila no ke kaʻina hana.

Pehea ka lōʻihi o ke kaʻina hana Gallium-68 DOTATOC?

ʻO ke kaʻina hana holoʻokoʻa e lawe ma kahi o 2-3 mau hola mai ka hoʻomaka ʻana a hiki i ka hopena. ʻO ka hoʻokomo maoli ʻana i ka mea huli e lawe wale i kekahi mau minuke, akā pono ʻoe e kali ma kahi o 45-60 mau minuke ma hope o ka hoʻokomo ʻana ma mua o ka hoʻomaka ʻana o ka scanning.

ʻO kēia manawa kali e hiki ai i ka mea huli ke hele i loko o kou kino a hōʻiliʻili i nā wahi kahi e loaʻa ai nā maʻi maʻi neuroendocrine. I kēia manawa, e noi ʻia ʻoe e hoʻomaha mālie a inu i ka wai e kōkua i ka holoi ʻana i ka mea huli ma o kāu ʻōnaehana.

ʻO ka scan PET maoli e lawe maʻamau i 20-30 mau minuke, i ka wā e pono ai ʻoe e moe mālie ma ka papa scanning. E neʻe ka mīkini a puni ʻoe e hopu i nā kiʻi mai nā kihi like ʻole.

He aha nā hopena ʻaoʻao o Gallium-68 DOTATOC?

ʻAʻole nui ka poʻe e ʻike i nā hopena ʻaoʻao mai Gallium-68 DOTATOC. Hoʻomanawanui maikaʻi ʻia ka mea huli, a he kakaikahi loa nā hopena koʻikoʻi.

ʻO nā mea maʻamau ka maʻalahi a me ka manawa pōkole, me kahi ʻono metala iki i kou waha ma hope koke o ka injection a i ʻole kahi manaʻo pōkole o ka mahana a i ʻole ke anuanu kahi i waiho ʻia ai ka IV. He mau minuke wale nō kēia mau manaʻo.

Eia nā hopena ʻaoʻao āu e ʻike ai, ʻoiai he mea maʻamau ʻole lākou:

• ʻO ka nausea māmā a i ʻole ka ʻoluʻolu o ka ʻōpū
• ʻO ke poʻo liʻiliʻi
• ʻO ka ʻeha manawa ma ke kahua injection
• ʻO ka luhi a i ʻole ka hiamoe ma hope o ke kaʻina hana

He kakaikahi loa nā hopena maʻi maʻi koʻikoʻi akā hiki ke komo i ka pilikia o ka hanu ʻana, ka pehu ʻana o ka maka a i ʻole ka ʻāʻī, a i ʻole nā hopena ʻili koʻikoʻi. Inā ʻike ʻoe i nā hōʻailona e pili ana, aia nā limahana lapaʻau ma kahi kokoke a mākaukau e kōkua.

ʻO wai ka mea pono ʻole e loaʻa iā Gallium-68 DOTATOC?

ʻAʻole ʻōlelo ʻia ʻo Gallium-68 DOTATOC no nā wahine hāpai no ka mea hiki i ka ʻike ʻana i ka radiation ke hōʻino i ka pēpē e ulu nei. Inā aia kekahi hiki ke hāpai ʻoe, e haʻi koke i kāu hui lapaʻau.

Pono nā makuahine e hānai ana i ka waiū e kūkākūkā i ka manawa me kā lākou kauka, no ka mea, hiki ke hele i loko o ka waiū umauma nā mea liʻiliʻi o ka mea huli. Hiki iā ʻoe ke ʻōlelo ʻia e pauma a hoʻolei i ka waiū umauma no 12-24 mau hola ma hope o ke kaʻina hana.

Pono paha ka poʻe me nā pilikia kīkī koʻikoʻi i ka noʻonoʻo kūikawā, no ka mea, ua hoʻopau ʻia ka mea huli ma nā kīkī. E loiloi kāu kauka i kāu hana kīkī ma mua o ka hoʻomau ʻana me ka scan.

Nā inoa inoa Gallium-68 DOTATOC

Loaʻa ʻo Gallium-68 DOTATOC ma lalo o ka inoa inoa NETSPOT ma ʻAmelika Hui Pū ʻIa. ʻO kēia ka mana i ʻae ʻia e ka FDA o ka mea huli i hoʻolālā ʻia no ka ʻike ʻana i nā maʻi neuroendocrine.

Ma nā ʻāina ʻē aʻe, loaʻa paha ia ma lalo o nā inoa inoa like ʻole a i ʻole he hoʻomākaukau i hana ʻia e nā radiopharmacies kūikawā. E hōʻoia kāu hui lapaʻau e loaʻa iā ʻoe ka hoʻomākaukau kūpono no kāu mau pono.

Nā Koho ʻē aʻe o Gallium-68 DOTATOC

Hiki ke hoʻohana ʻia kekahi mau mea hana kiʻi ʻē aʻe e ʻike i nā maʻi neuroendocrine, ʻoiai he mau mea maikaʻi a me nā palena o kēlā me kēia. ʻO Gallium-68 DOTATATE (inoa inoa NETSPOT) ua like loa me DOTATOC a kuhikuhi i nā mea hoʻokipa like me nā ʻano paʻa iki.

ʻO Indium-111 octreotide (OctreoScan) he mea hana kiʻi kahiko i hoʻohana ʻia i kekahi mau kikowaena. ʻOiai he mea pono, pono ia i nā manawa kiʻi lōʻihi a hāʻawi i nā kiʻi liʻiliʻi i hoʻohālikelike ʻia me nā mea hana gallium-68.

ʻO Fluorine-18 DOPA kekahi mea hana PET e hiki ke ʻike i kekahi mau maʻi neuroendocrine, ʻo ia hoʻi nā mea e hana ai i nā hormones kikoʻī. E koho kāu kauka i ka mea hana kūpono loa e pili ana i kāu kūlana kikoʻī a me ke ʻano o ka maʻi i manaʻo ʻia.

ʻOi aku ka maikaʻi o Gallium-68 DOTATOC ma mua o nā ʻano hana kiʻi ʻē aʻe?

ʻOi aku ka maikaʻi a me ka pololei o nā scans Gallium-68 DOTATOC PET ma mua o nā ʻano hana kiʻi kuʻuna e like me CT a i ʻole MRI scans no ka ʻike ʻana i nā maʻi neuroendocrine. Hiki iā lākou ke ʻike i nā maʻi liʻiliʻi a hāʻawi i ka ʻike maikaʻi e pili ana i ka laha ʻana o ka maʻi.

Hoʻohālikelike ʻia me ka OctreoScan kahiko, hāʻawi nā mea hana gallium-68 i ka maikaʻi kiʻi kiʻekiʻe a me nā manawa scanning wikiwiki. Hoʻopau ʻia ke kaʻina hana i hoʻokahi lā ma mua o ka pono ʻana i nā kipa he nui i nā lā he nui.

Eia naʻe, loaʻa i kēlā me kēia ʻano hana kiʻi kona wahi i ka mālama olakino. Hiki i kāu kauka ke ʻōlelo aku i ka hoʻohui ʻana i nā scans PET me nā ʻenehana kiʻi ʻē aʻe e kiʻi i ke kiʻi piha loa o kou kūlana.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Gallium-68 DOTATOC

He palekana ʻo Gallium-68 DOTATOC no ka poʻe me ka maʻi diabetes?

ʻAe, palekana ʻo Gallium-68 DOTATOC no ka poʻe me ka maʻi diabetes. ʻAʻole pili ka mea huli i nā pae kōpaʻa koko a i ʻole ke keakea ʻana i nā lāʻau lapaʻau diabetes. Hiki iā ʻoe ke hoʻomau i ka lawe ʻana i kāu mau lāʻau lapaʻau diabetes maʻamau e like me ke kauoha.

Eia naʻe, e hōʻike i kāu hui lapaʻau e pili ana i kāu maʻi diabetes i hiki iā lākou ke nānā pono iā ʻoe i ka wā o ke kaʻina hana. Inā hoʻohana ʻoe i ka insulin, pono paha ʻoe e hoʻoponopono i kāu papa hana dosing e pili ana i kāu papa ʻai a puni ka scan.

He aha kaʻu e hana ai inā maikaʻi ʻole wau ma hope o ka injection?

Inā ʻike ʻoe i nā hōʻailona maʻamau ma hope o ka loaʻa ʻana o Gallium-68 DOTATOC, e hoʻomaopopo koke i nā limahana lapaʻau. Ua aʻo ʻia lākou e mālama i nā hopena a loaʻa nā lako pilikia i loaʻa.

ʻO ka hapa nui o nā hopena ʻaoʻao he maʻalahi a he manawa pōkole, akā ʻoi aku ka maikaʻi o ka hōʻike ʻana i nā hopohopo ma mua o ka hopohopo e pili ana iā lākou. ʻO nā ʻike maʻamau e like me ka nausea iki a i ʻole ka dizziness e hoʻoponopono maʻamau me ka hoʻomaha a me ka hydration.

Hiki iaʻu ke hoʻokele i ka home ma hope o ke kaʻina hana?

ʻAe, hiki iā ʻoe ke hoʻokele i ka home ma hope o ka scan Gallium-68 DOTATOC. ʻAʻole hana ke kaʻina hana i ka hiamoe a i ʻole e hoʻopilikia i kou hiki ke hoʻokele palekana. ʻAʻole pili ka mea huli i kāu mau reflexes a i ʻole ka noʻonoʻo.

Eia naʻe, manaʻo kekahi poʻe i ka luhi iki ma hope o ka moe ʻana no ka manawa lōʻihi i ka wā o ka scan. Inā manaʻo ʻoe i ka luhi ʻole a i ʻole maikaʻi ʻole, he mea naʻauao ke hoʻonohonoho i kekahi e hoʻokele iā ʻoe i ka home.

Pehea ka lōʻihi o ka noho ʻana o ka radioactivity i loko o koʻu kino?

E emi koke ana ka radioactivity mai Gallium-68 DOTATOC a ua pau loa mai kou kino i loko o 24 mau hola. He pōkole loa ka hapalua o ke ola o ka gallium-68, ʻo ia hoʻi, e emi ana kona radioactivity e ka hapalua i kēlā me kēia 68 mau minuke.

E aʻo ʻia ʻoe e inu i ka wai nui ma hope o ke kaʻina hana e kōkua i ka holoi ʻana i ka mea huli mai kāu ʻōnaehana me ka wikiwiki. I ka lā aʻe, ʻaʻole hiki ke ʻike ʻia nā pae radioactivity a ʻaʻole ia e hōʻike i ka pilikia iā ʻoe a i ʻole nā ​​poʻe ʻē aʻe a puni ʻoe.

Pono anei au e pale i ka pilina me nā poʻe ʻē aʻe ma hope o ka scan?

I nā hola mua ma hope o kāu scan, pono ʻoe e mālama i ka mamao pilikanaka maʻamau mai nā wahine hāpai a me nā keiki ʻōpio ma ke ʻano he hana palekana. He ana palekana wale nō kēia ma muli o ka liʻiliʻi o ka radioacticity i loko o kou kino.

ʻAʻole pono ʻoe e hoʻokaʻawale iā ʻoe iho, akā ʻo ka pale ʻana i ka pili kokoke a lōʻihi me nā kānaka nāwaliwali no ke koena o ka lā e ʻōlelo ʻia. I ke kakahiaka aʻe, ʻaʻohe kapu i kāu mau hana maʻamau a i ʻole nā pilina me nā poʻe ʻē aʻe.