He aha ka Gallium Ga-68 PSMA-11: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Gallium Ga-68 PSMA-11 he mea hana kiʻi radioactive i hoʻohana ʻia e ʻike i ka maʻi maʻi prostate i laha ma waho o ka ʻōpū prostate. Kōkua kēia scan kūikawā i nā kauka e ʻike pololei i kahi e hūnā ai nā sela maʻi maʻi i loko o kou kino, e hāʻawi ana iā lākou i kahi kiʻi maopopo loa ma mua o nā ʻano hana kiʻi kuʻuna. E noʻonoʻo iā ia he mea ʻike koʻikoʻi hiki ke ʻike i nā sela maʻi maʻi prostate ma nā wahi a pau i hele ai, e kōkua ana i kāu hui lapaʻau e hoʻolālā i ke ala lapaʻau maikaʻi loa no kāu kūlana.

He aha ka Gallium Ga-68 PSMA-11?

ʻO Gallium Ga-68 PSMA-11 he mea hana radioactive e pili ana i kahi protein i kapa ʻia ʻo PSMA (prostate-specific membrane antigen) i loaʻa ma nā sela maʻi maʻi prostate. Ke hoʻokomo ʻia i loko o kou kahe koko, hele kēia mea hana i loko o kou kino a paʻa i kēia mau sela maʻi maʻi, e ʻike ʻia lākou ma kahi ʻano scan kūikawā i kapa ʻia he PET scan.

ʻO ka ʻāpana

Hoʻohana nā kauka i kēia scan e kōkua i ka hoʻolālā ʻana i nā hoʻolālā lapaʻau, e hoʻoholo inā hiki ke hana ʻia ke ʻoki, a i ʻole e nānā i ka maikaʻi o ka hana ʻana o nā lapaʻau i kēia manawa. Kōkua nā kiʻi kikoʻī i kāu hui lapaʻau e hana i nā hoʻoholo i ʻike ʻia e pili ana i kāu mālama.

Pehea e hana ai ʻo Gallium Ga-68 PSMA-11?

Hana kēia tracer ma ka ʻimi ʻana iā PSMA, kahi protein i loaʻa i nā mea nui aʻe ma nā pūnaewele maʻi maʻi prostate i hoʻohālikelike ʻia me nā pūnaewele maʻamau. Ke hoʻokomo ʻia ka tracer radioactive, hele ia ma kou kahe koko a pili pono i kēia mau pūnaewele maʻi.

A laila hoʻopuka ka tracer pili i nā hōʻailona e hōʻike ana i ka mālamalama ma kahi scan PET, e hana ana i kahi palapala kikoʻī o kahi e loaʻa ai nā pūnaewele maʻi i loko o kou kino. Lawe pinepine kēia hana ma kahi o 60 a 90 mau minuke ma hope o ka hoʻokomo ʻana no ka tracer e hāʻawi pono i loko o kāu ʻōnaehana.

Manaʻo ʻia ka ikaika kiʻi o kēia mea hana he mea ikaika loa ia no ka ʻike ʻana i ka maʻi maʻi prostate. Hiki iā ia ke ʻike i nā wahi maʻi liʻiliʻi e like me kekahi mau millimeters, e lilo ia i kekahi o nā mea hana maʻalahi loa i loaʻa no ka ʻike ʻana i ka maʻi maʻi prostate.

Pehea wau e hoʻomākaukau ai no Gallium Ga-68 PSMA-11?

E maʻalahi kāu hoʻomākaukau ʻana, akā ʻo ka hahai ʻana i nā ʻōlelo aʻoaʻo e kōkua i ka hōʻoia ʻana i nā kiʻi maikaʻi loa. E noi pinepine ʻia ʻoe e inu i ka wai nui ma mua o kāu manawa a e hoʻomau i ka inu ʻana i ka wai ma hope o ka hoʻokomo ʻana e kōkua i ka holoi ʻana i ka tracer ma kāu ʻōnaehana.

Pono ʻoe e ʻai i ka meaʻai māmā ma mua o ka hele ʻana mai, no ka mea, ʻaʻohe palena meaʻai kūikawā no kēia scan. Eia naʻe, e pale i nā lāʻau lapaʻau e hiki ke hoʻopilikia i ka tracer ke ʻole e haʻi pololei kāu kauka iā ʻoe.

E hoʻolālā e hoʻolilo ma kahi o 3 a 4 mau hola ma ke kikowaena kiʻi. Ma hope o ka loaʻa ʻana o ka injection, e kali ʻoe ma kahi o 60 a 90 mau minuke ma mua o ka hoʻomaka ʻana o ka scanning maoli. I loko o kēia manawa kali, hiki iā ʻoe ke hoʻomaha, heluhelu, a i ʻole e hoʻolohe i ke mele i ka wā e hāʻawi ai ka tracer i loko o kou kino.

Pehea ka lōʻihi o ke kaʻina hana Gallium Ga-68 PSMA-11?

ʻO ka hana holoʻokoʻa e lawe maʻamau i 3 a 4 mau hola mai ka hoʻomaka a hiki i ka hopena. Aia kēia i ka injection mua, ka manawa kali, a me ke kaʻina hana scanning maoli.

Ma hope o kou loaʻa ʻana i ka injection, e kali ʻoe ma kahi o 60 a 90 mau minuke i ka wā e hele ai ka tracer ma kou kino a pili i nā cell cancer. ʻO ka scan PET maoli e lawe maʻamau ma kahi o 20 a 30 mau minuke, i ka wā e moe mālie ai ʻoe ma luna o kahi papa e hele ana i loko o ka scanner.

He pōkole loa ka hapalua o ke ola o ka radioactive tracer, ʻo ia hoʻi, e lilo ana i mea liʻiliʻi. E hala ka hapa nui o ka radioactivity mai kou kino i loko o 24 mau hola, a hiki iā ʻoe ke hoʻi i nā hana maʻamau ma hope koke o ka scan.

He aha nā hopena ʻaoʻao o Gallium Ga-68 PSMA-11?

ʻO ka nūhou maikaʻi, he kakaikahi loa nā hopena ʻaoʻao mai kēia mea hana kiʻi a he maʻalahi loa ke hana. ʻAʻole ʻike ka hapa nui o nā kānaka i nā hopena ʻaoʻao mai ka injection.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike, ʻoiai e pili ana lākou i kahi pākēneka liʻiliʻi o nā maʻi:

• ʻO ka nausea māmā a i ʻole ka ʻoluʻolu o ka ʻōpū
• ʻO ke poʻo liʻiliʻi
• He ʻono metala manawa i kou waha
• ʻO ka huhū a i ʻole ka ʻulaʻula o ka pūnaewele injection
• ʻO ka manaʻo ʻana i ka dizziness a i ʻole ka māmā no ka manawa pōkole

ʻO kēia mau hōʻailona, ​​inā loaʻa, he maʻalahi loa a hoʻoponopono i loko o kekahi mau hola. ʻO ka haʻahaʻa haʻahaʻa a me ka pōkole o ka tracer i loko o kou kino e hana i nā hopena ʻaoʻao koʻikoʻi.

ʻO nā hopena ʻaoʻao kakaikahi akā ʻoi aku ka koʻikoʻi e pili ana i nā hopena maʻi, ʻoiai he mea maʻamau kēia. ʻO nā hōʻailona e pili ana i ka pilikia o ka hanu ʻana, ka nausea nui, a i ʻole ka pehu nui. Ua mākaukau kāu hui lapaʻau e mālama i nā hopena i manaʻo ʻole ʻia, ʻoiai he kakaikahi loa lākou me kēia tracer.

ʻO wai ka mea pono ʻole e loaʻa iā Gallium Ga-68 PSMA-11?

ʻOiai he palekana kēia mea hana kiʻi no ka hapa nui o nā kānaka, aia kekahi mau kūlana e koho ai kāu kauka i kahi ala ʻokoʻa. Hoʻoholo mau ʻia ka hoʻoholo ʻana ma ka loiloi ʻana i nā pōmaikaʻi o ka loaʻa ʻana o ka ʻike diagnostic koʻikoʻi e kūʻē i nā pilikia hiki ke loaʻa.

E noʻonoʻo pono kāu kauka i kou kūlana pilikino inā he pilikia koʻikoʻi kou puʻupaʻa, no ka mea, pono e hiki i kou kino ke hana a hoʻopau pono i ka mea huli. Pono paha ka poʻe me kekahi mau ʻano maʻi maʻi i nā mea hana kiʻi i nā hana kūikawā a i ʻole nā ​​ʻano kiʻi ʻē aʻe.

Inā ua hoʻonohonoho ʻia ʻoe no nā kaʻina hana lapaʻau ʻē aʻe a i ʻole nā ​​scan, e hoʻonohonoho kāu kauka i ka manawa e hōʻoia i nā hopena maikaʻi loa mai nā mea ʻelua. I kekahi manawa he mea nui ka mamao ma waena o nā ʻano kiʻi like ʻole no ka pololei.

Nā inoa inoa ʻo Gallium Ga-68 PSMA-11

Loaʻa kēia mea hana kiʻi ma lalo o ka inoa inoa Pylarify ma ʻAmelika Hui Pū ʻIa. ʻO ia ka mea mua a ʻo ka mana i ʻae ʻia e ka FDA o Gallium Ga-68 PSMA-11 no ka hoʻohana ʻana i ka ʻoihana ma nā halemai ʻAmelika a me nā kikowaena kiʻi.

Na kāu kauka a i ʻole ke kikowaena kiʻi e mālama i nā hoʻomākaukau a me ka lawelawe ʻana i kēia lāʻau. ʻAʻole ia he mea e loaʻa ai a mālama paha ʻoe iā ʻoe iho, no ka mea, pono ia i nā lako kūikawā a me ka loea e hoʻomākaukau palekana.

Nā koho ʻē aʻe ʻo Gallium Ga-68 PSMA-11

Hiki i kekahi mau ʻano kiʻi ʻē aʻe ke kōkua i ka ʻike ʻana i ka maʻi maʻi prostate, ʻoiai he ikaika a me nā palena like ʻole. ʻO nā koho kuʻuna e pili ana i nā scan CT, nā scan MRI, a me nā scan iwi, akā ʻaʻole i maʻalahi kēia mau mea ma mua o ka PSMA PET scanning.

ʻO kekahi koho hou ʻo Fluciclovine F-18 (Axumin), ʻo ia hoʻi he mea huli PET no ka maʻi maʻi prostate. Eia naʻe, ʻoi aku ka maikaʻi o ka Gallium Ga-68 PSMA-11 no nā cell maʻi prostate a hāʻawi pinepine i nā kiʻi maopopo.

E ʻōlelo aku kāu kauka i ke ala kiʻi kiʻi maikaʻi loa e pili ana i kou kūlana kikoʻī, me kou mōʻaukala maʻi ʻaʻai, nā pae PSA o kēia manawa, a me ka ʻike e pono ai lākou e alakaʻi i kāu mau hoʻoholo lapaʻau.

Ua ʻoi aku ka maikaʻi o Gallium Ga-68 PSMA-11 ma mua o nā scans maʻi ʻaʻai prostate ʻē aʻe?

Ua manaʻo ʻia ʻo Gallium Ga-68 PSMA-11 PET scanning i kēia manawa kekahi o nā hana kiʻi kiʻi maʻalahi a kikoʻī loa no ka ʻike ʻana i ka hoʻi hou ʻana o ka maʻi ʻaʻai prostate. Loaʻa pinepine ia i ka maʻi ʻaʻai ke ʻike ʻia nā scans ʻē aʻe he maʻamau, ʻoiai ke haʻahaʻa mau nā pae PSA.

I ka hoʻohālikelike ʻana me nā scans CT a i ʻole nā iwi kuʻuna, hiki i ka PSMA PET imaging ke ʻike i nā waihona maʻi ʻaʻai liʻiliʻi a hāʻawi i ka ʻike wahi pololei. Kōkua kēia i nā kauka e hana i nā hoʻoholo lapaʻau maikaʻi a hiki ke hōʻike i kekahi manawa ʻoi aku ka nui a i ʻole ka liʻiliʻi o ka maʻi ʻaʻai ma mua o ka manaʻo o nā kiʻi ʻē aʻe.

Eia naʻe, ʻo ka scan

ʻAʻole hiki ke loaʻa ka nui o kēia mea hana kiʻi no ka mea ua hoʻomākaukau ʻia a lawelawe ʻia e nā poʻe loea lāʻau lapaʻau nukelea i aʻo ʻia me ka hoʻohana ʻana i nā ana pololei. Hoʻohālikelike ʻia nā ʻano lāʻau lapaʻau me ke akahele e pili ana i kou kaumaha kino a me nā koi kiʻi kikoʻī.

Inā hopohopo ʻoe e pili ana i ka lāʻau lapaʻau āu i loaʻa ai, e kamaʻilio koke me kāu hui lāʻau lapaʻau nukelea. Hiki iā lākou ke hōʻoluʻolu a nānā iā ʻoe inā pono, ʻoiai he kakaikahi loa nā pilikia koʻikoʻi mai nā lāʻau lapaʻau kiʻi.

Q3. He aha kaʻu e hana ai inā e hala wau i kaʻu manawa Gallium Ga-68 PSMA-11 i hoʻonohonoho ʻia?

E hoʻokaʻaʻike i kāu kikowaena kiʻi i ka hiki wawe e hoʻonohonoho hou i kāu manawa. No ka mea, ua hoʻomākaukau ʻia kēia mea huli no kēlā me kēia maʻi a he ola pōkole loa, ʻo ka hala ʻana i kāu manawa, ʻaʻole hiki ke hoʻohana ʻia ka lāʻau lapaʻau i hoʻomākaukau ʻia.

E hana pū ke kikowaena kiʻi me ʻoe e hoʻonohonoho i kahi manawa hou, ʻoiai aia paha kahi manawa kali e pili ana i kā lākou papa manawa a me ka manawa e pono ai e hoʻomākaukau i kahi lāʻau lapaʻau hou o ka mea huli.

Q4. I ka manawa hea e loaʻa ai iaʻu kaʻu hopena scan Gallium Ga-68 PSMA-11?

ʻO ka maʻamau, e lawe ʻia ana kāu hopena scan i 1 a 2 mau lā ʻoihana e loiloi piha ʻia a hōʻike ʻia. E nānā pono kahi loea lāʻau lapaʻau nukelea i nā kiʻi a pau a hoʻomākaukau i kahi hōʻike kikoʻī no kāu kauka.

A laila e hoʻokaʻaʻike kāu kauka iā ʻoe e kūkākūkā i nā hopena a me ke ʻano o lākou no kāu hoʻolālā lapaʻau. Hiki i kekahi mau kikowaena kiʻi ke hāʻawi i ka ʻike mua i ka lā hoʻokahi, akā e lawe ana ka loiloi piha i kahi manawa liʻiliʻi e hōʻoia i ka pololei.

Q5. Hiki iaʻu ke noho kokoke i nā lālā o ka ʻohana ma hope o ka loaʻa ʻana o Gallium Ga-68 PSMA-11?

ʻAe, hiki iā ʻoe ke noho palekana me nā lālā o ka ʻohana, me nā keiki a me nā wahine hāpai, ma hope koke o kāu scan. He liʻiliʻi loa ka nui o ka radioactivity a e emi koke ana, ʻaʻole ia e pilikia i nā poʻe ʻē aʻe a puni ʻoe.

Hiki paha iā ʻoe ke ʻōlelo ʻia e inu i nā wai hou aʻe no ke koena o ka lā e kōkua ai i ka holoi ʻana i ka mea huli mai kāu ʻōnaehana me ka wikiwiki, akā ʻaʻole pono ka hoʻokaʻawale ʻana a i ʻole nā hana kūikawā ma ka home.