He aha ʻo Ibritumomab: Nā Hoʻohana, Nā Ana, Nā ʻAoʻao ʻAoʻao a me nā mea hou aku

He lāʻau lapaʻau maʻi ʻo Ibritumomab e hui pū ana i ka lāʻau lapaʻau i manaʻo ʻia me ka lāʻau lapaʻau radioactive e hakakā i kekahi mau ʻano maʻi koko. Hana kēia lāʻau lapaʻau e like me ka missile alakaʻi, e ʻimi ana a hoʻopili i nā cell maʻi kikoʻī i loko o kou kino ma mua o ka hāʻawi ʻana i ka radiation pololei e luku iā lākou. Hoʻohana nui ʻia ia no ka mālama ʻana i ka non-Hodgkin's lymphoma, kahi ʻano maʻi koko e pili ana i kāu ʻōnaehana lymphatic.

He aha ʻo Ibritumomab?

ʻO Ibritumomab kahi lāʻau radioimmunotherapy e hui pū ana i kahi antibody me kahi mea radioactive. E noʻonoʻo iā ia he lāʻau lapaʻau ʻelua ʻāpana kahi e hana ai ka antibody e like me ka ʻōnaehana GPS, e ʻimi ana i nā cell maʻi, ʻoiai ka ʻāpana radioactive e hāʻawi ana i ka radiation i manaʻo ʻia e luku iā lākou. ʻO ka inoa piha āu e ʻike ai ʻo ibritumomab tiuxetan, a hāʻawi ʻia ma o ka laina IV i loko o kou kahe koko.

No ka papa i kapa ʻia ʻo monoclonal antibodies kēia lāʻau lapaʻau, he mau protein i hoʻolālā kūikawā ʻia e hiki ke ʻike a hoʻopaʻa i nā pahuhopu kikoʻī ma nā cell maʻi. ʻO ka mea e kū hoʻokahi ai ʻo ibritumomab ʻo ia ka

Pehea e Hana ai ʻo Ibritumomab?

Hana ʻo Ibritumomab ma ka hāʻawi ʻana i ka radiation i nā pūnaewele maʻi maʻi me ka hōʻemi ʻana i ka pōʻino i nā pūnaewele olakino. ʻImi ka ʻāpana antibody i nā protein CD20 i loaʻa ma ka ʻili o kekahi mau pūnaewele lymphoma. Ke loaʻa a pili i kēia mau pūnaewele, hāʻawi ka ʻāpana radioactive i ka radiation i kālele ʻia e luku i nā pūnaewele maʻi maʻi mai loko mai.

Manaʻo ʻia he lāʻau lapaʻau maʻi maʻi ikaika i kālele ʻia ma mua o ka chemotherapy kuʻuna. He pōkole ka radiation e hāʻawi ai, ʻo ia hoʻi, pili nui ia i nā pūnaewele maʻi maʻi i pili ai ma mua o ka laha ʻana i kou kino holoʻokoʻa. Hiki i kēia hana i kālele ʻia ke kōkua i ka hōʻemi ʻana i kekahi o nā hopena ʻaoʻao āu e ʻike ai me nā lāʻau lapaʻau radiation ākea.

Pehea e Lawe ai au iā Ibritumomab?

Hāʻawi ʻia ʻo Ibritumomab ma kahi haukapila a i ʻole ke kikowaena lapaʻau maʻi maʻi e nā poʻe loea mālama ola i aʻo ʻia. E loaʻa iā ʻoe ma o ka laina IV, ʻo ia hoʻi, hele pololei ia i loko o kou kahe koko ma o ka nila i kou lima a i ʻole ma o kahi laina waena inā loaʻa iā ʻoe.

ʻO ka maʻamau, pili ka lapaʻau i ʻelua mau infusions i hāʻawi ʻia ma kahi o hoʻokahi pule. Ma mua o kēlā me kēia infusion, e loaʻa iā ʻoe nā lāʻau lapaʻau ʻē aʻe e kōkua i ka hoʻomākaukau ʻana i kou kino a hōʻemi i ka pilikia o nā hopena maʻi. ʻAʻole pono ʻoe e ʻai a pale paha i ka ʻai ʻana ma mua o ka lapaʻau, akā e hāʻawi kāu hui mālama ola iā ʻoe i nā ʻōlelo kikoʻī e pili ana i kou kūlana pilikino.

I ka wā o ka infusion, e nānā pono ʻia ʻoe no nā hopena. Hiki i ke kaʻina hana infusion ke lawe i kekahi mau hola, no laila makemake paha ʻoe e lawe i kekahi mea e hōʻoluʻolu iā ʻoe, e like me ka puke a i ʻole ke mele. Ma hope o ka lapaʻau, pono ʻoe e hahai i nā hana kūikawā no ka mea e loaʻa iā ʻoe nā mea radioactive i loko o kou kino no kekahi mau lā.

Pehea ka lōʻihi e lawe ai au iā Ibritumomab?

Hāʻawi ʻia ʻo Ibritumomab ma ke ʻano he papa lapaʻau hoʻokahi ma mua o ka lāʻau lapaʻau e hoʻomau nei. Loaʻa i ka hapa nui o nā kānaka nā infusions ʻelua ma kahi o ʻehiku a ʻeiwa mau lā ma hope, a hoʻopau i kēlā i ke kaʻina lapaʻau. ʻAʻole like me nā lāʻau lapaʻau i kēlā me kēia lā, he hoʻokahi wale nō kēia lapaʻau.

E nānā kāu kauka i kāu pane ʻana i ka lapaʻau i nā pule a me nā mahina e hiki mai ana ma o nā hoʻokolohua koko a me nā haʻawina kiʻi. Ma muli o ke ʻano o ka pane ʻana o kāu maʻi maʻi a me kou olakino holoʻokoʻa, hiki i kāu hui mālama ola ke ʻōlelo aku i nā lapaʻau hou, akā ʻaʻole pinepine ʻia ʻo ibritumomab iho ma muli o kāna hopena i kou iwi iwi.

He aha nā hopena ʻaoʻao o Ibritumomab?

E like me nā lapaʻau maʻi maʻi, hiki i ka ibritumomab ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole i ʻike nā kānaka a pau iā lākou ma ke ʻano like. Pili ka hapa nui o nā hopena ʻaoʻao i kāna hopena i kāu mau keena koko a me ka ʻōnaehana pale.

Eia nā hopena ʻaoʻao āu e ʻike nui ai, me ka noʻonoʻo ʻana e nānā pono kāu hui mālama ola iā ʻoe a kōkua i ka mālama ʻana i nā hōʻailona e kū mai ana:

• Nā helu keena koko haʻahaʻa (me nā keʻena koko keʻokeʻo, nā keʻena koko ʻulaʻula, a me nā platelets)
• Luhi a me ka nāwaliwali
• Hoʻonui i ka pilikia o nā maʻi
• Maʻalahi ka ʻeha a i ʻole ke kahe ʻana
• Nausea a me ka pilikia digestive
• Fiva a me nā anu
• Nā hopena maʻi i ka wā o ka infusion

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau. Aia kēia mau mea hiki ʻole ke loaʻa i ka hāʻule nui ʻana o nā helu keena koko e hiki ke hoʻoweliweli i ke ola, nā maʻi koʻikoʻi, a i ʻole nā maʻi maʻi lua e ulu ana i nā mahina a i ʻole nā makahiki ma hope. E kūkākūkā kāu hui mālama ola i kēia mau pilikia me ʻoe a nānā pono iā ʻoe i ka wā a ma hope o ka lapaʻau.

ʻO wai ka mea pono ʻole e lawe iā Ibritumomab?

ʻAʻole kūpono ʻo Ibritumomab no nā mea a pau, a e loiloi pono kāu kauka inā kūpono ia nāu. ʻAʻole pono ʻoe e loaʻa i kēia lapaʻau inā hāpai ʻoe a i ʻole e hānai ana i ka waiū, no ka mea, hiki i ka radiation ke hōʻino i kahi pēpē e ulu ana.

E akahele nō hoʻi kāu kauka i ka ʻōlelo ʻana iā ibritumomab inā loaʻa iā ʻoe kekahi mau maʻi olakino. Pono kēia mau kūlana i ka noʻonoʻo kūikawā a hiki ke hana i kēia lapaʻau kūpono ʻole nāu:

• Nā helu koko haʻahaʻa loa ma mua o ka lapaʻau
• Lapaʻau radiation nui ma mua
• Hoʻopili ʻia ka iwi iwi me nā pūnaewele lymphoma ma mua o 25%
• Nā pilikia koʻikoʻi o ka puʻuwai, ka māmā, a i ʻole nā puʻupaʻa
• Nā maʻi hana
• Mōʻaukala o nā hopena maʻi maʻi koʻikoʻi i nā lāʻau lapaʻau like

E hana kāu hui mālama ola i nā hoʻokolohua piha ma mua o ka lapaʻau e hōʻoia i hiki i kou kino ke mālama i kēia lāʻau lapaʻau me ka palekana. E noʻonoʻo pū lākou i kou olakino holoʻokoʻa, nā lapaʻau ma mua, a me nā lāʻau lapaʻau i kēia manawa e hoʻoholo ai inā ʻo ibritumomab ke koho maikaʻi loa no kāu kūlana.

Inoa Brand Ibritumomab

Kūʻai ʻia ʻo Ibritumomab ma lalo o ka inoa brand Zevalin. Ke ʻike ʻoe i kēia inoa ma kāu hoʻolālā lapaʻau a i ʻole nā pepa ʻinikua, ke kuhikuhi nei ia i ka lāʻau lapaʻau like. Hiki i kekahi mau mea mālama ola ke hoʻohana i kekahi inoa ke kūkākūkā i kāu lapaʻau, no laila, mai huikau inā lohe ʻoe i nā huaʻōlelo ʻelua.

Hana ʻia ʻo Zevalin e nā hui lāʻau lapaʻau kūikawā a loaʻa wale nō ma o nā kikowaena lapaʻau maʻi maʻi kūikawā. E hana kāu hui mālama ola me nā mea hoʻolako kūpono e hōʻoia e loaʻa iā ʻoe ka lāʻau lapaʻau ke pono ʻoe.

Nā Koho ʻē aʻe o Ibritumomab

Inā ʻaʻole kūpono ʻo ibritumomab nāu, hiki ke loaʻa i kekahi mau koho lapaʻau ʻē aʻe no kāu ʻano lymphoma. Hiki i kāu kauka ke ʻōlelo i nā antibodies monoclonal ʻē aʻe e like me rituximab, e kuhikuhi ana i ka protein CD20 like akā ʻaʻole ia e lawe i nā mea radioactive.

Hiki i nā koho ʻē aʻe ke komo i nā ʻano lapaʻau i manaʻo ʻia, nā hui chemotherapy kuʻuna, a i ʻole nā lapaʻau hou e like me ka CAR-T cell therapy, ma muli o kou kūlana kikoʻī. E hana pū kāu oncologist me ʻoe e ʻimi i ka lapaʻau kūpono loa e pili ana i kāu ʻano maʻi maʻi, ke olakino holoʻokoʻa, a me ka mōʻaukala lapaʻau.

Ua ʻoi aku ka maikaʻi o Ibritumomab ma mua o Rituximab?

Hoʻopā ʻo Ibritumomab a me rituximab i ka protein CD20 like ma nā cell lymphoma, akā hana lākou i nā ʻano like ʻole. He

Q2. He aha kaʻu e hana ai inā loaʻa iaʻu ka nui loa o Ibritumomab?

No ka mea, hāʻawi ʻia ʻo ibritumomab e nā poʻe loea mālama ola i aʻo ʻia ma nā keʻena lapaʻau, he mea maʻamau loa ka overdose ulia pōpilikia. Hoʻohālikelike ʻia ka lāʻau lapaʻau ma muli o ke kaumaha o kou kino a hāʻawi ʻia ma lalo o ka mālama olakino koʻikoʻi.

Inā hopohopo ʻoe e pili ana i kāu mahele a i ʻole e ʻike i nā hōʻailona maʻamau ma hope o ka mālama ʻana, e hoʻokaʻaʻike koke i kāu hui mālama ola. Hiki iā lākou ke loiloi i kou kūlana a hāʻawi i ka mālama kūpono inā pono. E loaʻa i ke keʻena lapaʻau kahi e loaʻa ai iā ʻoe ka mālama ʻana i nā protocols e mālama ai i nā pilikia e kū mai ana.

Q3. He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Ibritumomab?

Inā hala ʻoe i kāu infusion ibritumomab i hoʻonohonoho ʻia, e hoʻokaʻaʻike koke i kāu hui mālama ola e hoʻonohonoho hou. No ka mea, pili kēia mālama ʻana i nā mea radioactive a hahai i kahi papa manawa kikoʻī, he mea nui e hoʻopili me kāu hui lapaʻau ma mua o ka hoʻāʻo ʻana e hoʻoponopono i ka papa manawa iā ʻoe iho.

Na kāu hui mālama ola e hoʻoholo i ke ala maikaʻi loa e hoʻomau ai ma muli o ka nui o ka manawa i hala a me kāu hoʻolālā lapaʻau holoʻokoʻa. Pono paha lākou e hoʻomaka hou i kekahi mau lāʻau lapaʻau hoʻomākaukau a i ʻole e hoʻoponopono i ka manawa o kāu pōʻaiapuni lapaʻau.

Q4. I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Ibritumomab?

Hāʻawi ʻia ʻo Ibritumomab ma ke ʻano he papa lapaʻau piha ma mua o ka lāʻau lapaʻau e hoʻomau nei. Loaʻa i ka hapa nui o nā kānaka ʻelua infusions ma kahi o hoʻokahi pule kaʻawale, a hoʻopau kēlā i ka mālama ʻana. ʻAʻole ʻoe e

He pōkole ka hapalua o ke ola o ka mea radioactive i loko o ka ibritumomab, ʻo ia hoʻi, e nalowale ana kona radioactivity i ka wikiwiki. E hala ana ka hapa nui o ka radioactivity mai kou kino i loko o ʻelua pule ma hope o ka lapaʻau ʻana, me nā pae kiʻekiʻe loa i nā lā mua.

I kēia manawa, pono ʻoe e hahai i nā hana kūikawā e pale aku i nā poʻe ʻē aʻe mai ka ʻike ʻana i ka radiation. E hāʻawi aku kāu hui mālama ola iā ʻoe i nā ʻōlelo kikoʻī e pili ana i ka noho ʻana ma kahi mamao palekana mai nā poʻe ʻē aʻe, ʻo ia hoʻi nā wahine hāpai a me nā keiki ʻōpio, a me ka hoʻolei pono ʻana i nā wai kino. He manawa pōkole kēia mau hana a e hoʻokuʻu ʻia lākou ke emi ka radioactivity i nā pae palekana.