He aha ka Ibuprofen Lysine (Ala Intravenous): Nā Hoʻohana, Dosage, Nā ʻAoʻao ʻAoʻao a me nā mea hou aku

He ʻano kūikawā ʻo Ibuprofen lysine o ka ibuprofen e hāʻawi ai nā kauka ma o ka laina IV (intravenous) pololei i loko o kou kahe koko. Hoʻolālā ʻia kēia lāʻau lapaʻau no nā pēpē hānau hou i loaʻa i kahi maʻi puʻuwai i kapa ʻia ʻo patent ductus arteriosus, kahi e pani ʻole ai kahi moku koko kokoke i ka puʻuwai ma hope o ka hānau ʻana.

ʻAʻole like me nā pila ibuprofen a i ʻole ka wai e lawe ai ʻoe ma ka home no ka ʻeha a i ʻole ke kuni, hana kēia mana IV i ka wikiwiki a me ka pololei. Hoʻohana ʻia ia i nā wahi haukapila ma lalo o ka mālama olakino akahele, e hāʻawi ana i nā kauka i ka mana maikaʻi aʻe i ka nui o ka lāʻau lapaʻau e loaʻa ai i kāu pēpē.

No ke aha e hoʻohana ʻia ai ka Ibuprofen Lysine?

He hoʻokahi pahuhopu nui ka Ibuprofen lysine: e kōkua i ka pani ʻana i ka patent ductus arteriosus (PDA) i nā pēpē hānau mua. ʻO ka PDA kahi moku koko liʻiliʻi e hoʻopili ana i ʻelua mau ʻaʻa nui kokoke i ka puʻuwai, a pono e pani maoli i loko o nā lā mua o ke ola.

Ke noho hāmama kēia moku i nā pēpē hānau mua, hiki iā ia ke hoʻoulu i nā pilikia hanu a hoʻokau i ke kaumaha hou i ka puʻuwai. Hana ka lāʻau lapaʻau ma ka pale ʻana i kekahi mau kemika i loko o ke kino e mālama i kēia moku e hāmama, e ʻae ana e pani maoli e like me ka mea e pono ai ma hope o ka hānau ʻana.

I kekahi manawa hiki i nā kauka ke hoʻohana i kēia lāʻau lapaʻau e kōkua i ka hōʻemi ʻana i ke kuni a i ʻole ka mumū i nā pēpē hānau hou i ka wā i kūpono ʻole ai nā lāʻau lapaʻau ʻē aʻe. Eia naʻe, ʻo ka pani ʻana o ka PDA ka mea nui a koʻikoʻi loa i nā wahi haukapila.

Pehea e hana ai ka Ibuprofen Lysine?

Ua manaʻo ʻia ʻo Ibuprofen lysine he lāʻau lapaʻau ikaika e hana ana ma ka pale ʻana i nā enzymes i kapa ʻia ʻo cyclooxygenases (COX enzymes). Hoʻopuka kēia mau enzymes i nā mea i kapa ʻia ʻo prostaglandins, e mālama ana i ka ductus arteriosus e hāmama i ka wā hāpai a me ke ola mua.

Ma ka hoʻēmi ʻana i kēia mau prostaglandins, hiki i ka lāʻau lapaʻau ke ʻae i ka ʻiʻo maʻemaʻe i loko o ka paia o ke kīʻaha koko e ʻaelike a pani i ka puka. Hana maʻamau kēia kaʻina hana i loko o 24 a 48 mau hola ma hope o ka mālama ʻana, akā pono paha kekahi mau pēpē i nā lāʻau he nui.

Kōkua ka ʻāpana lysine o ka lāʻau lapaʻau i ka hana ʻana i ka ibuprofen i ʻoi aku ka wai-soluble, ʻo ia hoʻi, hiki ke hāʻawi ʻia me ka palekana ma o ka laina IV. Kōkua pū kēia i ka lāʻau lapaʻau e hana wikiwiki ma mua o nā ʻano waha no ka mea e hele pololei ana i loko o ke kahe koko.

Pehea e hāʻawi ʻia ai ka Ibuprofen Lysine?

Hāʻawi mau ʻia ka ibuprofen lysine e nā limahana o ka haukapila i aʻo ʻia ma o ka laina IV, ʻaʻole ma ka waha a i ʻole ma ka home. Hele mai ka lāʻau lapaʻau ma ke ʻano he pauka e hui pū ai nā kahu hānai a i ʻole nā ​​kauka me ka wai sterile ma mua pono o ka hāʻawi ʻana i kāu pēpē.

Hāʻawi ʻia ka lāʻau lapaʻau i ka lohi ma kahi o 15 mau minuke ma o ka laina IV. ʻAʻole pono kāu pēpē e ʻai a inu paha i kekahi mea kūikawā ma mua a ma hope paha o ka loaʻa ʻana o kēia lāʻau lapaʻau no ka mea e hele pololei ana i loko o kā lākou kahe koko.

Loaʻa ka hapa nui o nā pēpē i kēia lapaʻau ʻoiai aia lākou i loko o ka neonatal intensive care unit (NICU) a i ʻole ka nursery mālama kūikawā. E nānā pono ka hui lapaʻau i ka helu o ka puʻuwai o kāu pēpē, ka hanu ʻana, a me nā hōʻailona koʻikoʻi ʻē aʻe i ka wā a ma hope o kēlā me kēia lāʻau.

Pehea ka lōʻihi e hoʻohana ʻia ai ka Ibuprofen Lysine?

Aia ka papa hana maʻamau i ʻekolu mau lāʻau i hāʻawi ʻia i nā lā he nui, maʻamau me 24-hola manawa ma waena o kēlā me kēia lāʻau. Pane maikaʻi ka hapa nui o nā pēpē i kēia hoʻolālā lapaʻau maʻamau, me ka pani piha ʻana o ka PDA i loko o kekahi mau lā.

Inā ʻaʻole hana ka papa mua, hiki i kāu kauka ke ʻōlelo aku i kahi pūʻulu ʻelua o ʻekolu mau lāʻau ma hope o ke kali ʻana i kekahi mau lā. Eia naʻe, inā ʻaʻole pani ka PDA ma hope o ʻelua mau papa piha, pono paha kāu pēpē i kahi ala lapaʻau ʻokoʻa.

ʻAʻole i ʻoi aku ka lōʻihi o ka manawa lapaʻau ma mua o hoʻokahi pule, a nui nā pēpē e ʻike i ka maikaʻi ma hope o ka lāʻau mua a i ʻole ka lua. E hoʻohana ana kāu hui lapaʻau i nā hoʻokolohua ultrasound e nānā inā e pani pono ana ka PDA i ka wā o ka lapaʻau.

He aha nā hopena ʻaoʻao o Ibuprofen Lysine?

E like me nā lāʻau lapaʻau a pau, hiki i ka ibuprofen lysine ke hana i nā hopena ʻaoʻao, akā nui nā pēpē e ʻae maikaʻi iā ia. Nānā pono ka hui lapaʻau i kēia mau hopena no ka mea ʻaʻole hiki i nā pēpē hānau hou ke haʻi iā mākou i ko lākou manaʻo.

Eia nā hopena ʻaoʻao maʻamau e nānā ai nā kauka i ka wā o ka lapaʻau:

• Nā loli i ka hana ʻana o ka mimi (e hana ana i ka mimi liʻiliʻi ma mua o ka maʻamau)
• Nā loli maʻalahi i ke koko
• Nā loli manawa i nā hoʻokolohua koko e ana ana i ka hana ʻana o nā puʻupaʻa
• Nā loli liʻiliʻi i ka helu o ka puʻuwai
• Hoʻopilikia ʻana i ka ʻōpū

Hoʻoponopono pinepine ʻia kēia mau hopena maʻamau a ʻaʻole lākou e hana i nā pilikia mau ke hopu ʻia i ka wā mua.

ʻAʻole maʻamau nā hopena ʻaoʻao koʻikoʻi, akā pono lākou i ka nānā koke ʻana mai kāu hui lapaʻau:

• Nā pilikia puʻupaʻa nui a i ʻole ka pau ʻana o ka hana mimi
• Ke kahe nui ʻana o ke koko, ʻoi aku hoʻi i ka lolo a i ʻole ka ʻōpū
• Nā pilikia puʻuwai koʻikoʻi
• Nā hopena maʻi koʻikoʻi me nā pilikia hanu
• Nā loli nui i ke koko

Nānā mau nā limahana o ka haukapila i kēia mau hopena koʻikoʻi, me ka hoʻohana ʻana i nā hoʻokolohua koko a me nā ana ʻē aʻe e hopu i nā pilikia i ka wā mua.

Hiki i kekahi mau hopena ʻaoʻao kakaʻikahi akā koʻikoʻi ke ulu i ka manawa, me nā pilikia lohe a i ʻole nā pilikia puʻupaʻa paʻakikī. E hoʻomau ana ka hui lapaʻau o kāu pēpē i ka nānā ʻana ma hope o ka pau ʻana o ka lapaʻau e hōʻoia i ka hoʻōla pono ʻana o nā mea a pau.

ʻO wai ka mea pono ʻole e loaʻa iā Ibuprofen Lysine?

ʻAʻole hiki i kekahi mau pēpē ke loaʻa palekana i ka ibuprofen lysine ma muli o nā kūlana olakino ʻē aʻe a i ʻole nā kūlana. E nānā pono kāu hui lapaʻau i ke kiʻi olakino piha o kāu pēpē ma mua o ka ʻōlelo ʻana i kēia lapaʻau.

ʻO nā pēpē ʻaʻole pono e loaʻa i kēia lāʻau lapaʻau, ʻo ia hoʻi nā mea me:

• Nā pilikia kīkī koʻikoʻi a i ʻole ka hana mimi haʻahaʻa loa
• Ke kahe koko ikaika ma nā wahi a pau o ke kino
• ʻO ka maʻi puʻuwai nui a i ʻole kekahi mau kīnā o ka puʻuwai
• Nā maʻi maʻi i ʻike ʻia i ka ibuprofen a i ʻole nā lāʻau lapaʻau like
• Nā pilikia ate nui
• Nā maʻi koko koko

Eia kekahi, ʻo nā pēpē hānau mua loa (ma lalo o 32 mau pule o ka hāpai ʻana) a i ʻole nā mea i emi iho ma mua o 1.5 paona ʻaʻole paha he moho maikaʻi no kēia lapaʻau.

ʻAʻole kūpono paha kekahi mau pēpē no ka lapaʻau inā he pilikia koʻikoʻi ko lākou i ka māmā, aia ma kekahi mau lāʻau lapaʻau ʻē aʻe, a i ʻole he mau maʻi olakino paʻakikī ʻē aʻe. E noʻonoʻo pono kāu neonatologist i kēia mau mea a pau ma mua o ka hoʻoholo ʻana i ka lapaʻau.

Nā inoa inoa o Ibuprofen Lysine

Loaʻa ka ibuprofen lysine no ka injection ma lalo o nā inoa inoa like ʻole, ʻo NeoProfen ka mea i hoʻohana nui ʻia ma ʻAmelika Hui Pū ʻIa. Loaʻa paha i nā ʻāina ʻē aʻe nā inoa inoa like ʻole no ka lāʻau lapaʻau like.

ʻAʻole pili i ka inoa inoa, aia nā mana a pau i ka mea hana like a hana ma ke ala like. E hoʻomākaukau ka hale kūʻai lāʻau lapaʻau o ka haukapila i ka mana i loaʻa iā lākou, a ua like ka maikaʻi o lākou a pau no ka mālama ʻana i ka PDA.

Nā koho ʻē aʻe o Ibuprofen Lysine

Inā ʻaʻole kūpono ka ibuprofen lysine no kāu pēpē a i ʻole ʻaʻole hana pono, loaʻa i nā kauka nā koho lapaʻau ʻē aʻe. Aia ke koho i ke kūlana kikoʻī o kāu pēpē a me ke olakino holoʻokoʻa.

ʻO ka mea lapaʻau nui ʻo indomethacin, kekahi lāʻau lapaʻau e hana like ana e pani i ka PDA. Ua pane maikaʻi kekahi mau pēpē i kekahi lāʻau lapaʻau ma mua o kekahi, a hiki i kāu kauka ke hoʻāʻo i ka indomethacin inā ʻaʻole hana ka ibuprofen lysine.

No nā pēpē ʻaʻole hiki ke loaʻa i kekahi lāʻau lapaʻau me ka palekana, he koho ka pani ʻana i ka PDA ma ke ʻoki. Pono kēia i kahi hana liʻiliʻi e pani mau i ka moku koko, i hana pinepine ʻia e ke kauka ʻoki puʻuwai pediatric.

I kekahi manawa, hiki i nā kauka ke ʻōlelo aku e nānā wale i ka PDA me ka ʻole o ka lāʻau lapaʻau koke, ʻoiai inā olakino kāu pēpē a he liʻiliʻi ka puka. Nui nā PDA liʻiliʻi e pani iā lākou iho i ka wā e ulu ikaika ai nā pēpē.

Ua ʻoi aku ka maikaʻi o ka Ibuprofen Lysine ma mua o Indomethacin?

He mau lāʻau lapaʻau maikaʻi ʻo Ibuprofen lysine a me indomethacin no ka pani ʻana i ka PDA i nā pēpē hou, a hōʻike ka noiʻi e hana like lākou no ka hapa nui o nā pēpē. ʻO ke koho ma waena o lākou e pili pinepine ana i nā pono olakino kikoʻī o kāu pēpē a me ka lāʻau lapaʻau e palekana paha.

Hiki i ka Ibuprofen lysine ke ʻoluʻolu i nā puʻupaʻa a hoʻoulu i nā loli liʻiliʻi i ke kahe koko i ka lolo a me nā ʻōkana ʻē aʻe. Hiki i kēia ke lilo i koho maikaʻi no nā pēpē i loaʻa mua i nā pilikia puʻupaʻa a i ʻole nā pilikia ʻē aʻe.

Ua hoʻohana ʻia ʻo Indomethacin no ka lōʻihi a hiki ke hana wikiwiki i kekahi mau hihia, akā hiki iā ia ke loaʻa nā hopena hou aʻe i ka hana puʻupaʻa a me ke kahe koko. E koho kāu hui lapaʻau i ka lāʻau lapaʻau i palekana a hiki ke hana no ke kūlana kūikawā o kāu pēpē.

Pono nā lāʻau lapaʻau ʻelua i ka nānā pono ʻana a loaʻa nā helu kūleʻa like no ka pani ʻana i nā PDA, no laila hiki i kekahi ke lilo i koho maikaʻi ke hoʻohana pono ʻia.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Ibuprofen Lysine

Q1. Palekana anei ka Ibuprofen Lysine no nā pēpē me nā pilikia puʻuwai?

He palekana ka Ibuprofen lysine no nā pēpē me ka PDA, ʻo ia hoʻi he maʻi puʻuwai. Eia naʻe, ʻaʻole kūpono paha nā pēpē me nā hemahema puʻuwai koʻikoʻi a i ʻole ka maʻi puʻuwai no kēia lāʻau lapaʻau.

E hana pū ana ke kauka naʻau o kāu pēpē a me ka neonatologist e hoʻoholo inā palekana kēia lāʻau lapaʻau e pili ana i ke ʻano a me ke koʻikoʻi o nā pilikia o ka naʻau. E noʻonoʻo lākou i ka maikaʻi o ka hana ʻana o ka naʻau o kāu pēpē a inā e kōkua ka pani ʻana i ka PDA a i ʻole e hana i nā pilikia ʻē aʻe.

Q2. He aha kaʻu e hana ai inā me he mea lā e pane maikaʻi ʻole ana kaʻu pēpē i ka Ibuprofen Lysine?

Inā ʻike ʻoe i nā loli i kāu pēpē i ka wā a i ʻole ma hope o ka mālama ʻana, e haʻi koke i kāu kahu hānai a i ʻole ke kauka. No ka mea aia kāu pēpē i ka haukapila, ke nānā mau nei ka hui lapaʻau i nā pilikia.

ʻO nā hōʻailona e hopohopo ai iā ʻoe e pili ana i nā loli i ke kala o ka ʻili, ka hiamoe ʻole a i ʻole ka maluhia, nā loli i nā ʻano hanu, a i ʻole inā me he mea lā ʻoluʻolu ʻole kāu pēpē. E hoʻomanaʻo e nānā ana ka hui lapaʻau i kēia mau mea, akā he mea waiwai mau kāu mau ʻike ma ke ʻano he makua.

Q3. He aha ka mea e hana ai inā e hala kaʻu pēpē i kahi mahele i hoʻonohonoho ʻia?

No ka mea e hāʻawi ʻia ka ibuprofen lysine i loko o ka haukapila, ʻaʻole paha e hala kahi mahele. Inā pono e hoʻopaneʻe ʻia kahi mahele ma muli o ke kūlana o kāu pēpē a i ʻole nā mea nui ʻē aʻe, e hoʻoponopono kāu hui lapaʻau i ka manawa kūpono.

ʻOi aku ka maikaʻi o ka lāʻau lapaʻau ke hāʻawi ʻia i nā manawa i hoʻonohonoho ʻia, akā ʻaʻole pili nā lohi liʻiliʻi i ka holomua o ka mālama ʻana. E hōʻoia kāu mau kauka e loaʻa i kāu pēpē ka papa piha o ka mālama ʻana ma ke ala palekana loa.

Q4. I ka manawa hea e hiki ai ke hoʻōki i ka mālama ʻana me ka Ibuprofen Lysine?

Hoʻōki maʻamau ka mālama ʻana ma hope o ka papa i hoʻolālā ʻia o ʻekolu mau mahele, a i ʻole ma mua inā hōʻike nā hoʻokolohua ua pani loa ka PDA. Hoʻohana kāu hui lapaʻau i nā hoʻokolohua ultrasound e nānā inā e pani pono ana ke kīʻaha koko ma hope o kēlā me kēia mahele.

Inā kū mai nā hopena ʻaoʻao koʻikoʻi, hiki i kāu mau kauka ke hoʻōki i ka mālama ʻana i ka wā mua a noʻonoʻo i nā koho ʻē aʻe. ʻO ka hoʻoholo e hoʻomau a hoʻōki paha i ka mālama ʻana e hilinaʻi mau ana i ka mea palekana a me ka pono loa no kāu pēpē i kēlā manawa.

Nīnau 5. E pono anei kaʻu pēpē i ka mālama ma hope o ka mālama ʻana me ka Ibuprofen Lysine?

ʻAe, e pono ana kāu pēpē i nā hoʻokolohua ultrasound ma hope e hōʻoia i ka pani ʻia ʻana o ka PDA ma hope o ka pau ʻana o ka mālama ʻana. Pono ka hapa nui o nā pēpē i nā hoʻokolohua koko e nānā i ka hoʻi ʻana o ka hana o ka puʻupaʻa i ke ʻano maʻamau.

Manaʻo ʻia ka mālama lōʻihi me kahi cardiologist pediatric e nānā i ke olakino o ka puʻuwai o kāu pēpē i ko lākou ulu ʻana. ʻO ka nūhou maikaʻi, ʻo nā pēpē i pani maikaʻi ʻia ko lākou PDA me ka lāʻau lapaʻau, he hopena maikaʻi loa lākou i ka wā lōʻihi a me ka hana maʻamau o ka puʻuwai.