Idursulfase (alaloa ma ke ala intravena)

Elaprase

Hoʻohana ʻia ka injection Idursulfase no ka mālama ʻana i ka maʻi Hunter (Mucopolysaccharidosis II, MPS II), kahi maʻi maʻamau ʻole e ʻike pinepine ʻia ma nā kāne. He maʻi hoʻoilina ka maʻi Hunter kahi i hemahema ai ka haki ʻana o kahi kemika kūikawā i loko o ke kino (mucopolysaccharide) ma muli o ka nele a i ʻole ka nele o kahi enzyme i kapa ʻia ʻo iduronate-2-sulfatase. Hoʻomaikaʻi ka Idursulfase i nā hōʻailona a me nā hōʻailona ma nā mea maʻi, ʻoi aku hoʻi ka hiki ke hele wāwae, ma o ka pani ʻana i ka enzyme i nele i ka maʻi Hunter. Loaʻa wale kēia lāʻau lapaʻau me ka palapala kauoha a kāu kauka. Loaʻa kēia huahana ma nā ʻano dosage e like me kēia:

I ka hoʻoholo ʻana e hoʻohana i kahi lāʻau lapaʻau, pono e kaulike ke kaumaha o ka lawe ʻana i ka lāʻau lapaʻau me ka pono e hana ai. He hoʻoholo kēia āu a me kāu kauka e hana ai. No kēia lāʻau lapaʻau, pono e noʻonoʻo i kēia mau mea: E haʻi aku i kāu kauka inā ua loaʻa iā ʻoe kekahi hopena maʻamau ʻole a i ʻole nā ​​mea ʻē aʻe paha i kēia lāʻau lapaʻau a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe paha. E haʻi aku pū i kāu limahana mālama ola inā loaʻa iā ʻoe nā ʻano ʻē aʻe o nā mea ʻē aʻe, e like me nā meaʻai, nā mea kala, nā mea mālama, a i ʻole nā ​​holoholona paha. No nā huahana ʻole-prescription, e heluhelu pono i ka lepili a i ʻole nā ​​mea hoʻohui pūʻolo. ʻAʻole i hōʻike nā haʻawina kūpono i hana ʻia a hiki i kēia lā i nā pilikia pili i nā keiki e kaupalena ai i ka hoʻohana ʻana o ka injection idursulfase i nā keiki. Eia naʻe, ʻaʻole i hoʻokumu ʻia ka palekana a me ka pono i nā keiki ʻoi aku ma lalo o 16 mau mahina o ka makahiki. ʻAʻole i hana ʻia nā haʻawina kūpono ma ka pilina o ka makahiki i nā hopena o ka injection idursulfase i ka heluna geriatric. ʻAʻole i hoʻokumu ʻia ka palekana a me ka pono. ʻAʻohe mau haʻawina lawa i nā wāhine no ka hoʻoholo ʻana i ka pilikia o ka pēpē i ka wā e hoʻohana ana i kēia lāʻau lapaʻau i ka wā hānai. E kaulike i nā pono hiki ke loaʻa me nā pilikia hiki ke loaʻa ma mua o ka lawe ʻana i kēia lāʻau lapaʻau i ka wā hānai. ʻOiai ʻaʻole pono e hoʻohana pū ʻia kekahi mau lāʻau lapaʻau, i nā hihia ʻē aʻe, hiki ke hoʻohana pū ʻia ʻelua mau lāʻau lapaʻau ʻokoʻa ʻoiai inā hiki ke loaʻa kahi pilina. I kēia mau hihia, makemake paha kāu kauka e hoʻololi i ka nui, a i ʻole nā ​​ʻano palekana ʻē aʻe paha e pono ai. E haʻi aku i kāu limahana mālama ola inā ke lawe nei ʻoe i kekahi lāʻau lapaʻau ʻē aʻe a i ʻole lāʻau lapaʻau ʻole (over-the-counter [OTC]). ʻAʻole pono e hoʻohana ʻia kekahi mau lāʻau lapaʻau a i ʻole kokoke i ka wā e ʻai ai i ka meaʻai a i ʻole ka ʻai ʻana i kekahi mau ʻano meaʻai ʻoiai paha e hiki mai nā pilina. ʻO ka hoʻohana ʻana i ka waiʻona a i ʻole ka paka me kekahi mau lāʻau lapaʻau e hiki ke hoʻokumu i nā pilina. E kūkākūkā me kāu limahana mālama ola i ka hoʻohana ʻana i kāu lāʻau lapaʻau me ka meaʻai, ka waiʻona, a i ʻole ka paka. Hiki i ke kū ʻana o nā pilikia olakino ʻē aʻe ke hoʻopilikia i ka hoʻohana ʻana i kēia lāʻau lapaʻau. E hōʻoia e haʻi aku i kāu kauka inā loaʻa iā ʻoe nā pilikia olakino ʻē aʻe, ʻoiai: