He aha ka Immune Globulin (IVIG): Nā Hoʻohana, Dosage, Nā ʻaoʻao ʻaoʻao a me nā mea hou aku

ʻO ka immune globulin, i ʻike ʻia ʻo IVIG (intravenous immunoglobulin), he huahana koko i hana ʻia mai nā antibodies i hāʻawi ʻia e nā tausani o nā kānaka olakino. Hāʻawi kēia lāʻau lapaʻau i kou ʻōnaehana pale i kahi hoʻoikaika ma ka hāʻawi ʻana i nā antibodies i hana mua ʻia e kōkua i ka hakakā ʻana i nā maʻi a hoʻomaha i nā pane immune overactive. E noʻonoʻo e like me ka hōʻaiʻē ʻana i ka ikaika mai nā poʻe ʻē aʻe ke pono kāu ʻōnaehana pale i ke kōkua hou.

He aha ka Immune Globulin?

ʻO ka immune globulin he hopena i hoʻopaʻa ʻia o nā antibodies i hōʻiliʻili ʻia mai ka plasma koko i hāʻawi ʻia. ʻO kēia mau antibodies nā protein hakakā maʻi like i hana maoli ai kou kino, akā mai nā mea hāʻawi like ʻole e hāʻawi iā ʻoe i ka pale ākea. Hoʻomaʻemaʻe pono ke kaʻina hana hana i kēia mau antibodies e palekana ai lākou no ka hoʻohana ʻana i ka lāʻau lapaʻau.

Aia i loko o kēia lāʻau lapaʻau ka immunoglobulin G (IgG), ʻo ia ke ʻano maʻamau o ka antibody o kou kino. Hōʻike nā antibodies i hāʻawi ʻia i ka pale mai nā tausani o nā kānaka, no laila hiki iā lākou ke ʻike a hakakā i nā germs a me nā maʻi like ʻole. ʻO kēia pale i hui pū ʻia e hana i ka IVIG i mea ikaika loa no ka poʻe ʻaʻole e hana pono ana kā lākou ʻōnaehana pale.

No ke aha e hoʻohana ʻia ai ka Immune Globulin?

Hoʻopaʻa nā kauka i ka immune globulin no nā kumu nui ʻelua: e pani i nā antibodies nalowale a i ʻole e hoʻomaha i kahi ʻōnaehana pale overactive. Inā ʻaʻole hiki i kou kino ke hana i nā antibodies lawa iā ia iho, hiki i ka IVIG ke hoʻopiha i kēlā āpau a kōkua i ka pale ʻana iā ʻoe mai nā maʻi koʻikoʻi.

Hoʻomaʻamaʻa ka lāʻau lapaʻau i kekahi mau maʻi e pono ai kāu ʻōnaehana pale i ke kākoʻo. Eia nā hoʻohana nui e noʻonoʻo ai kāu kauka:

• Nā maʻi immunodeficiency mua (i ka wā e hānau ʻia ai me ka ʻōnaehana pale maʻi nāwaliwali)
• Chronic inflammatory demyelinating polyneuropathy (CIDP), he maʻi aʻalolo
• Idiopathic thrombocytopenic purpura (ITP), kahi e luku ai kou kino i kāna mau platelets ponoʻī
• Maʻi Kawasaki i nā keiki, e hoʻoulu ai i ka mumū o nā kīʻaha koko
• Leukemia lymphocytic maʻi me nā maʻi pinepine
• Multifocal motor neuropathy, he maʻi aʻalolo laha ʻole

Hoʻohana kekahi mau kauka i ka IVIG no nā maʻi autoimmune ʻē aʻe, ʻoiai ke aʻo ʻia nei kēia mau hoʻohana. E noʻonoʻo pono kāu mea mālama ola i nā pōmaikaʻi a me nā pilikia e pili ana i kāu kūlana.

Pehea e hana ai ka Immune Globulin?

Hana ka immune globulin ma ka hāʻawi pololei ʻana i kāu kahe koko i nā antibodies e hakakā ana i ka maʻi. Hoʻomaka koke kēia mau antibodies e mākaʻikaʻi i kou kino, e ʻimi ana i nā germs a me nā mea hoʻoweliweli ʻē aʻe e hiki ai iā lākou ke ʻike a hoʻopau. Hoʻomaka kēia kaʻina hana i ka wā e komo ai ka lāʻau lapaʻau i kou kahe koko.

No nā maʻi immunodeficiency, hana ka IVIG e like me ka therapy pani. Hāʻawi ia i nā antibodies e pono ai kou kino e hana akā ʻaʻole hiki ke hana i nā mea lawa. Noho nā antibodies i hōʻaiʻē ʻia i loko o kāu ʻōnaehana no kekahi mau pule, e hāʻawi ana iā ʻoe i ka pale i kēlā manawa.

I ka mālama ʻana i nā maʻi autoimmune, hana ʻokoʻa ka IVIG. Kōkua ia i ka hoʻomaha ʻana i kāu ʻōnaehana pale maʻi a hoʻemi i ka mumū. ʻAʻole maopopo loa ke ʻano kikoʻī, akā me he mea lā e hoʻonohonoho hou ka lāʻau lapaʻau i ke kaulike o kāu ʻōnaehana pale a hoʻemi i ka mumū ʻino.

Pehea wau e lawe ai i ka Immune Globulin?

E loaʻa iā ʻoe ka immune globulin ma o kahi laina IV i kou lima, maʻamau i ka haukapila a i ʻole ke kikowaena infusion. Maʻamau ka hana ʻana i 2-4 mau hola, a e nānā ʻia ʻoe i ka manawa holoʻokoʻa. E hoʻomaka kāu hui mālama ola i ka infusion mālie a hoʻonui mālie i ka wikiwiki i ka wā e hoʻoponopono ai kou kino.

Ma mua o kāu hoʻokomo ʻana, hiki iā ʻoe ke ʻai maʻamau a pono ʻoe e inu i ka wai nui e noho hydrated. Manaʻo kekahi mau kauka e lawe i ka acetaminophen (Tylenol) ma kahi o 30 mau minuke ma mua o ka mālama ʻana e pale aku i nā ʻeha poʻo a i ʻole nā hopena maʻalahi. E hāʻawi kāu mea mālama ola iā ʻoe i nā ʻōlelo kikoʻī e pili ana i kāu mau pono.

I ka wā o ka hoʻokomo ʻana, pono ʻoe e noho mālie akā hiki iā ʻoe ke heluhelu, nānā i ke TV, a i ʻole e hana i nā hana mālie ʻē aʻe. E haʻi koke i kāu kahu hānai inā ʻoe e ʻike i ka ʻūlū, loaʻa ka ʻeha poʻo, a i ʻole e ʻike i nā hopena ʻili. ʻO ka hapa nui o nā kānaka e ʻae maikaʻi i ka mālama ʻana, ʻoiai ma hope o nā kau mua.

Pehea ka lōʻihi e lawe ai au i ka Immune Globulin?

ʻO ka lōʻihi o ka mālama ʻana e pili ana i kou kūlana a me ka maikaʻi o kou pane ʻana i ka lāʻau lapaʻau. No ka immunodeficiency mua, pono paha ʻoe i ka IVIG no ke ola, me nā hoʻokomo ʻana i kēlā me kēia 3-4 pule. Kōkua kēia mālama mau i ka mālama ʻana i nā pae antibody paʻa i loko o kou koko.

No nā kūlana autoimmune e like me ITP a i ʻole CIDP, ʻokoʻa ka lōʻihi o ka mālama ʻana. Pono kekahi poʻe i kekahi mau lāʻau, aʻo kekahi e koi i nā hoʻokomo mahina no nā mahina a i ʻole nā makahiki. E nānā kāu kauka i kāu mau hōʻailona a me nā hoʻokolohua koko e hoʻoholo ai i ka papa manawa kūpono no ʻoe.

Mai hooki i ka mālama ʻana i ka IVIG me ka ʻole e kamaʻilio mua me kāu kauka. No nā kūlana maʻi pale, hiki i ka hooki ʻana i ka hopena ke waiho iā ʻoe i nā maʻi koʻikoʻi. E kōkua kāu mea mālama ola iā ʻoe e hoʻomaopopo i ka mea e manaʻo ai a i ka manawa e palekana ai e hōʻemi a hoʻōki paha i ka mālama ʻana.

He aha nā hopena ʻaoʻao o ka Immune Globulin?

ʻO ka hapa nui o nā kānaka e ʻae maikaʻi i ka immune globulin, akā e like me nā lāʻau lapaʻau, hiki iā ia ke hana i nā hopena ʻaoʻao. ʻO nā hopena maʻamau ka maʻamau a hana i ka wā a i ʻole ma hope koke o ka hoʻokomo ʻana. Hoʻomaikaʻi pinepine kēia mau hopena ʻaoʻao me nā helu hoʻokomo lohi a i ʻole ka lāʻau lapaʻau mua.

Eia nā hopena ʻaoʻao maʻalahi a me ka maʻalahi e hiki iā ʻoe ke ʻike:

• ʻEha poʻo (ka hopena ʻaoʻao maʻamau)
• Luhi a i ʻole ka manaʻo luhi
• Hānō a i ʻole ka ʻōpū ʻoluʻolu
• ʻEha ʻiʻo a i ʻole ka ʻeha hui
• Hiva ʻoluʻolu a i ʻole nā anu
• Pāpaʻa ʻili a i ʻole ka ʻū
• ʻEha a i ʻole ka pehu ma ke kahua IV

Hoʻoponopono maʻamau kēia mau hopena i loko o hoʻokahi a ʻelua paha lā ma hope o ka mālama ʻana. Hiki i kāu hui mālama ola ke pale a hōʻemi paha i kēia mau hopena ma ka hoʻoponopono ʻana i kāu helu infusion a i ʻole ka hāʻawi ʻana iā ʻoe i ka lāʻau mua.

ʻOiai he mea maʻamau, ʻike kekahi poʻe i nā hopena ʻaoʻao koʻikoʻi e koi ai i ka lāʻau lapaʻau koke. ʻO kēia mau hopena maʻamau akā koʻikoʻi e komo pū ana:

• Nā hopena maʻi maʻi koʻikoʻi (anaphylaxis)
• Nā koko koko i nā wāwae, nā māmā, a i ʻole ka lolo
• Nā pilikia o ka puʻupaʻa a i ʻole ka hāʻule
• ʻEha poʻo koʻikoʻi e hōʻike ana i ka pehu o ka lolo
• Paʻakikī ka hanu ʻana a i ʻole ka ʻeha o ka umauma
• Nā loli ʻike koke

Mālama pono kāu hui lapaʻau iā ʻoe i ka wā a ma hope o nā infusions e nānā i kēia mau hopena koʻikoʻi. ʻAʻole ʻike ka hapa nui o nā kānaka i kēia mau hopena ʻaoʻao koʻikoʻi, akā he mea nui e ʻike i nā hōʻailona hōʻailona.

ʻO wai ka mea ʻaʻole pono e lawe i ka Immune Globulin?

ʻAʻole palekana ka immune globulin no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana. ʻO nā kānaka me kekahi mau maʻi e kū ana i nā pilikia kiʻekiʻe a pono paha i nā lāʻau lapaʻau ʻē aʻe a i ʻole nā hana kūikawā.

ʻAʻole pono ʻoe e loaʻa iā IVIG inā loaʻa iā ʻoe kahi hopena maʻi maʻi koʻikoʻi i nā immunoglobulins a i ʻole kekahi mea i loko o ka lāʻau lapaʻau. ʻO nā kānaka me ka nele o ka IgA koho i loaʻa nā antibodies anti-IgA e kū ana i kahi pilikia kiʻekiʻe o nā hopena maʻi maʻi koʻikoʻi.

Nui nā maʻi lapaʻau e koi ai i ka mālama kūikawā ke noʻonoʻo ʻia ka lāʻau IVIG. E kaupaona kāu kauka i nā pōmaikaʻi e kūʻē i nā pilikia hiki ke loaʻa inā loaʻa iā ʻoe:

• Ka maʻi kīkī a i ʻole ka mōʻaukala o nā pilikia kīkī
• Ka maʻi puʻuwai a i ʻole nā mea pilikia no nā ʻōpū koko
• Maʻi kō a i ʻole pre-diabetes
• Mōʻaukala o ka hahau ʻana a i ʻole nā ʻōpū koko
• Anemia koʻikoʻi a i ʻole nā maʻi koko
• Ka lāʻau lapaʻau hou me nā lāʻau lapaʻau ola

ʻAʻole pinepine ka hāpai ʻana a me ka hānai ʻana i ka waiū e pale ai i ka hoʻohana ʻana i ka IVIG, no ka mea, ua manaʻo ʻia ka lāʻau lapaʻau he palekana i kēia mau manawa. Eia naʻe, e nānā pono kāu kauka iā ʻoe a kūkākūkā i nā hopohopo kikoʻī e pili ana i kou kūlana.

Nā inoa inoa o ka Immune Globulin

He nui nā hui lāʻau lapaʻau e hana i nā huahana immune globulin, kēlā me kēia me nā ʻano like ʻole a me nā ʻano like ʻole. E koho kāu kauka i ka inoa inoa kikoʻī e pili ana i kou kūlana, ka ʻae ʻana, a me ka loaʻa. ʻO nā inoa inoa maʻamau e komo pū ana me Gammagard, Privigen, Octagam, a me Gammaplex.

ʻOiai aia i loko o kēia mau huahana ka lāʻau lapaʻau like, hiki ke ʻokoʻa i ka nui o ke kō, nā mea mālama, a i ʻole nā pae sodium. ʻOi aku ka maikaʻi o kekahi poʻe i kekahi mau inoa inoa ma mua o nā mea ʻē aʻe, no laila e hoʻololi paha kāu kauka i nā ʻano inā loaʻa iā ʻoe nā hopena ʻaoʻao.

ʻAʻole pinepine ka koho ʻana i ka inoa inoa i ka maikaʻi o ka lāʻau lapaʻau no kou kūlana. E koho kāu hui mālama ola i ke koho kūpono loa e pili ana i kāu mau pono pilikino a me ka mōʻaukala olakino.

Nā koho ʻē aʻe o ka Immune Globulin

No kekahi mau kūlana, hiki ke loaʻa nā lāʻau lapaʻau ʻē aʻe inā ʻaʻole kūpono a maikaʻi paha ka IVIG iā ʻoe. Hāʻawi ka subcutaneous immunoglobulin (SCIG) i hoʻokahi koho, kahi e loaʻa ai iā ʻoe nā mea liʻiliʻi ma lalo o ka ʻili i nā manawa pinepine, pinepine ma ka home.

ʻO nā koho ʻē aʻe e pili ana i kou kūlana kikoʻī. No nā maʻi autoimmune, hiki i kāu kauka ke noʻonoʻo i nā corticosteroids, nā lāʻau lapaʻau immunosuppressive ʻē aʻe, a i ʻole nā lāʻau lapaʻau i manaʻo ʻia. No ka nele o ka pale ʻana, hiki i ka transplantation cell stem ke koho i nā hihia koʻikoʻi.

A koho maikaʻi loa e hilinaʻi ana i kāu maʻi, ke koʻikoʻi o nā hōʻailona, a me ke olakino holoʻokoʻa. E kūkākūkā kāu mea mālama ola i nā koho i loaʻa a kōkua iā ʻoe e hoʻomaopopo i nā pōmaikaʻi a me nā hemahema o kēlā me kēia ala.

Ua ʻoi aku ka maikaʻi o ka Immune Globulin ma mua o nā lāʻau lapaʻau ʻē aʻe?

ʻAʻole pono ka immune globulin i

He pinepine ka nui loa o ka immune globulin ma muli o ka hāʻawi ʻia ʻana o ka lāʻau lapaʻau me ka mālie ma lalo o ka mālama ʻana o ke kauka. Inā loaʻa iā ʻoe ka nui loa, hiki iā ʻoe ke ʻike i nā hopena ʻaoʻao ʻoi aku ka ikaika e like me ke poʻo nui, ka nausea, a i ʻole ka nui o ka wai. E nānā pono kāu hui lapaʻau iā ʻoe a hāʻawi i ka mālama kākoʻo.

Ke kālele nei ka mālama ʻana i ka nui loa i ka mālama ʻana i nā hōʻailona a me ke kākoʻo ʻana i nā hana maoli o kou kino. Ua ola maikaʻi ka hapa nui o nā kānaka me ka mālama lapaʻau kūpono, akā pono paha ʻoe e noho i ka haukapila no ka nānā ʻana.

He aha kaʻu e hana ai inā e poina iaʻu kahi mahele o ka Immune Globulin?

Inā e poina iā ʻoe kahi infusion IVIG i hoʻonohonoho ʻia, e hoʻokaʻaʻike i kāu mea mālama ola i ka hiki wawe e hoʻonohonoho hou. Mai kali a hiki i kāu manawa kūpono e hiki mai ana, ʻoiai inā he maʻi pale ʻoe. Hiki i ka poina ʻana i nā mahele ke waiho iā ʻoe i ka pilikia i nā maʻi a i ʻole e ʻae i kāu mau hōʻailona e ʻino.

Na kāu kauka e hoʻoholo i ka manawa maikaʻi loa no kāu mahele makeup e pili ana i ka manawa i loaʻa ai iā ʻoe ka lāʻau lapaʻau a me kou kūlana kikoʻī. Hiki iā lākou ke hoʻoponopono i kāu papa manawa e hiki mai ana e pale aku i nā mahele i poina ʻia i ka wā e hiki mai ana.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Immune Globulin?

Ke hilinaʻi nei ka hoʻoholo e hooki i ka immune globulin i kāu kūlana kumu a me ka pane ʻana i ka lāʻau lapaʻau. No ka immunodeficiency mua, pono paha ʻoe i ka lāʻau lapaʻau i ke ola a pau e mālama i ka pale ʻana i nā maʻi. ʻO ka hooki ʻana hiki ke waiho iā ʻoe i ka pilikia nui i nā maʻi e hoʻoweliweli ana i ke ola.

No nā maʻi autoimmune, hiki i kāu kauka ke noʻonoʻo e hōʻemi a hooki paha i ka lāʻau lapaʻau inā e hoʻomaikaʻi a paʻa kāu mau hōʻailona. Pono kēia hoʻoholo i ka nānā pono ʻana a me ka hoʻohaʻahaʻa ʻana ma mua o ka hoʻōki koke ʻana. Mai hooki i ka IVIG ma kāu iho me ka ʻole o ka mālama lapaʻau.

Hiki iaʻu ke hele i ka wā e lawe ana i ka Immune Globulin?

ʻAe, hiki iā ʻoe ke hele i ka wā e loaʻa ana ka lapaʻau immune globulin, akā pono e hoʻolālā mua. Pono ʻoe e hoʻopili me nā keʻena mālama ola ma kou wahi e hele ai a i ʻole e hoʻonohonoho i kāu huakaʻi e pili ana i kāu papa manawa infusion. Hoʻonohonoho kekahi poʻe e loaʻa ka lapaʻau ma nā kikowaena infusion ma nā kūlanakauhale ʻē aʻe.

No ka huakaʻi honua, e lawe mai i nā palapala e pili ana i kāu lapaʻau a me ke kūlana olakino. E noʻonoʻo i ka ʻinikua huakaʻi e uhi ana i nā lapaʻau lapaʻau, a e lawe mau i ka ʻike pili pilikia no kāu hui mālama ola. Hiki i kāu kauka ke hāʻawi i kahi leka e wehewehe ana i kou pono no kēia lāʻau.