He aha ka Iobenguane I-123: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO ka Iobenguane I-123 he lāʻau lapaʻau radioactive kūikawā i hoʻohana ʻia no ke kiʻi ʻana i ka lāʻau lapaʻau, ʻoi aku ka nui o ka ʻike ʻana i kekahi mau ʻano maʻi maʻi i loko o kou kino. Hana kēia mea injectable e like me ka mea mākaʻi, e hele ana ma kou kahe koko e ʻimi a hōʻike i nā cell kikoʻī e hiki ke hoʻopilikia i ke olakino.

Hiki paha iā ʻoe ke manaʻo nui i ka lohe ʻana e pili ana i nā lāʻau lapaʻau radioactive, akā ua hoʻohana palekana ʻia kēia mea hana kiʻi no nā makahiki he nui e kōkua i nā kauka e kiʻi i nā kiʻi maopopo o ka mea e hana nei i loko o kou kino. He maʻalahi loa ka mea radioactive a ua hoʻolālā ʻia e haʻalele maoli i kāu ʻōnaehana i loko o kekahi mau lā.

He aha ka Iobenguane I-123?

ʻO ka Iobenguane I-123 he mea huli radioactive e like me kahi kemika maoli i kapa ʻia ʻo norepinephrine i loko o kou kino. Ke hoʻokomo ʻia i loko o kou kahe koko, hele ia i nā ʻano cell nerve a me nā cell tumor e omo i kēia ʻano kemika.

ʻO ka ʻāpana

He mea waiwai nō hoʻi ka lāʻau lapaʻau no ka ʻike ʻana i ka neuroblastoma, he ʻano maʻi maʻi e pili pinepine ana i nā keiki a e ulu mai ana mai nā pūnaewele nerve ʻōpio. Eia kekahi, kōkua ia i ka loiloi ʻana i nā maʻi carcinoid, he mau maʻi maʻi e ulu mālie ana a hiki ke loaʻa i nā ʻāpana like ʻole o kou kino.

Ma waho aʻe o ka ʻike ʻana i nā ʻōpū, hiki i kēia mea hana kiʻi ke loiloi i ka maikaʻi o ka hana ʻana o kāu ʻōnaehana nerve sympathetic. Hoʻomalu kēia ʻōnaehana i nā hana kino maʻalahi e like me ka helu o ka puʻuwai, ke koko, a me ka ʻai ʻana. Ke pono nā kauka e hoʻomaopopo inā e hana pono ana kekahi mau ala nerve, hāʻawi kēia scan i ka ʻike koʻikoʻi.

Pehea e Hana ai ʻo Iobenguane I-123?

Hana ʻo Iobenguane I-123 ma ka hoʻohālike ʻana i ka norepinephrine, he kemika maoli e hoʻohana ai kou kino e kamaʻilio ma waena o nā pūnaewele nerve. Ke hoʻokomo ʻia, hele ia ma kou kahe koko a komo i loko o nā pūnaewele e lawe maʻamau i ka norepinephrine.

Hoʻopuka ka iodine radioactive i pili i ka iobenguane i nā kukuna gamma i hiki ke ʻike ʻia e nā kamera kūikawā i kapa ʻia he mau kamera gamma a i ʻole SPECT scanners. Hana kēia mau kamera i nā kiʻi kikoʻī e hōʻike ana i kahi i hōʻiliʻili ai ka lāʻau lapaʻau i loko o kou kino.

Ua manaʻo ʻia he mea radioactive maʻalahi kēia i hoʻohālikelike ʻia me kekahi mau kaʻina hana lāʻau lapaʻau nukelea ʻē aʻe. He haʻahaʻa ka hōʻike ʻana i ka radiation a ua like ia me ka mea āu e loaʻa ai mai nā hoʻokolohua kiʻi lapaʻau ʻē aʻe e like me nā scan CT. E emi ana ka radioactivity ma ke ʻano maoli i ka wā, me ka hapa nui o ia mea e haʻalele ana i kou kino i loko o kekahi mau lā.

Pehea e Lawe ai au i ka Iobenguane I-123?

Hāʻawi mau ʻia ʻo Iobenguane I-123 ma ke ʻano he injection pololei i loko o ke aʻa, maʻamau i kou lima. ʻAʻole hiki iā ʻoe ke lawe i kēia lāʻau lapaʻau ma ka waha, a pono e lawelawe ʻia e nā poʻe loea mālama ola i hoʻomaʻamaʻa ʻia i loko o kahi keʻena lapaʻau i lako no nā kaʻina hana lāʻau lapaʻau nukelea.

Ma mua o kāu pahu, e hāʻawi paha kāu kauka iā ʻoe i ka potassium iodide a i ʻole kekahi lāʻau e pale ana i ka iodine e pale ai i kou ʻāʻī. E lawe maʻamau ʻoe i kēia lāʻau pale ʻāʻī e hoʻomaka ana i 24 mau hola ma mua o kāu pahu a e hoʻomau ana no kekahi mau lā ma hope.

ʻAʻole pono ʻoe e ʻai wikiwiki ma mua o ke kaʻina hana, akā e noi paha kāu kauka iā ʻoe e pale i kekahi mau meaʻai a i ʻole nā lāʻau lapaʻau e hiki ke hoʻopilikia i nā hopena kiʻi. He mea nui e noho maikaʻi i ka wai ma ka inu ʻana i ka wai nui ma mua a ma hope o ka pahu e kōkua i ka holoi ʻana i ka lāʻau mai kou ʻōnaehana.

He mau minuke wale nō ka pahu maoli, akā pono ʻoe e hoʻi no nā hālāwai kiʻi, maʻamau 24 mau hola ma hope o ka pahu a i kekahi manawa hou ma 48 mau hola. I loko o kēia mau hālāwai kiʻi, e moe mālie ʻoe ma luna o kahi papaʻaina i ka wā e kiʻi ai nā kamera i nā kiʻi o kou kino.

Pehea ka lōʻihi e lawe ai au i ka Iobenguane I-123?

Hāʻawi ʻia ka Iobenguane I-123 ma ke ʻano he pahu hoʻokahi no kēlā me kēia haʻawina kiʻi. ʻAʻole ʻoe e lawe i kēia lāʻau lapaʻau ma ke kumu e like me kāu e hana ai me nā pila a i ʻole nā lāʻau lapaʻau i kēlā me kēia lā.

ʻO nā hopena o ka lāʻau lapaʻau e mau ana no ka lōʻihi e pono ai e hoʻopau i kāu haʻawina kiʻi, ʻo ia ka mea maʻamau 24 a 48 mau hola ma hope o ka pahu. I loko o kēia manawa, e emi mālie ana ka mea radioactive i ka ikaika a ua hoʻopau ʻia mai kou kino ma o ka mimi a me nā neʻe ʻana o ka ʻōpū.

Inā pono kāu kauka i nā kiʻi hou a i ʻole nā haʻawina e hahai ai, e hoʻonohonoho lākou i nā manawa kaʻawale me nā pahu hou. ʻO ka manawa ma waena o nā haʻawina hou e hilinaʻi ana i kāu kūlana olakino kikoʻī a me ka mea a kāu kauka e nānā nei.

He aha nā hopena ʻaoʻao o Iobenguane I-123?

ʻAʻole nui ka poʻe e ʻike i nā hopena ʻaoʻao mai Iobenguane I-123, a he kakaikahi loa nā hopena koʻikoʻi. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a he manawa pōkole, e hana ana i kahi pākēneka liʻiliʻi o nā maʻi.

Eia nā hopena ʻaoʻao e hiki ke loaʻa iā ʻoe, me ka noʻonoʻo ʻana ʻaʻole pilikia ka hapa nui o nā kānaka:

• ʻO ka nausea māmā a i ʻole ka manaʻo ʻoluʻolu, e hala ana i loko o kekahi mau hola
• ʻO ka ʻūlū māmā a i ʻole ka māmā ma hope koke o ka injection
• ʻO ka ʻeha liʻiliʻi a i ʻole ka ʻeha ma kahi o ka injection
• ʻO ka ʻono metala manawa i kou waha
• ʻO ke poʻo māmā e hoʻoponopono iā ia iho

ʻAʻole maʻamau nā hopena ʻaoʻao koʻikoʻi akā hiki ke komo i nā hopena maʻi e like me ka ʻili ʻili, ka ʻūlū, a i ʻole ka pilikia o ka hanu. Inā loaʻa iā ʻoe kekahi mau hōʻailona koʻikoʻi e like me ka ʻeha o ka umauma, ka nausea koʻikoʻi, a i ʻole nā ​​hōʻailona o ka hopena maʻi, e ʻimi koke i ka lāʻau lapaʻau.

Ke hopohopo nei kekahi poʻe e pili ana i ka ʻike ʻana i ka radiation, akā ua manaʻo ʻia ka nui o ka radiation mai kēia kaʻina hana he palekana a ua helu ʻia e nā loea lāʻau lapaʻau nuklea. He manawa pōkole ka ʻike ʻana i ka radiation a nui ka mea e haʻalele i kou kino i nā hola 24 mua.

ʻO wai ka mea ʻaʻole pono e lawe iā Iobenguane I-123?

ʻAʻole pono nā wahine hāpai e loaʻa iā Iobenguane I-123 no ka mea hiki i nā mea radioactive ke hōʻeha i kahi pēpē e ulu ana. Inā loaʻa kekahi manawa e hāpai ana ʻoe, e haʻi i kāu kauka ma mua o ke kaʻina hana i hiki iā lākou ke hana i kahi hoʻāʻo hāpai.

Pono nā wahine e hānai ana i ka umauma i ka noʻonoʻo kūikawā no ka mea hiki i ka mea radioactive ke hele i loko o ka waiū umauma. E kūkākūkā kāu kauka inā pono ʻoe e hooki i ka hānai ʻana i ka umauma no ka manawa a i ʻole inā ʻoi aku ka maikaʻi o ka hoʻāʻo ʻana ma mua o nā pilikia.

Pono paha ka poʻe me ka maʻi kīkī koʻikoʻi i nā hoʻoponopono ʻana i ka maʻi a i ʻole nā ​​ʻano hana kiʻi ʻē aʻe no ka mea ua hoʻopau ʻia ka lāʻau lapaʻau ma nā puʻupaʻa. E nānā kāu kauka i kāu hana kīkī ma mua o ka hoʻomau ʻana me ka injection.

Inā he maʻi ʻoe i ka iodine a i ʻole he mau hopena koʻikoʻi i nā mea ʻokoʻa, e haʻi i kāu hui lapaʻau. ʻOiai he kakaikahi nā hopena i Iobenguane I-123, makemake paha kāu kauka e hana i nā hana hou aʻe a i ʻole e noʻonoʻo i nā ʻano hana kiʻi ʻē aʻe.

Nā inoa inoa o Iobenguane I-123

Loaʻa ʻo Iobenguane I-123 ma lalo o nā inoa inoa like ʻole, ʻo AdreView ka mea i hoʻohana nui ʻia ma ʻAmelika Hui Pū ʻIa. Hana ʻia kēia inoa inoa no ke kiʻi ʻana i nā lāʻau lapaʻau a kū i nā kūlana kiʻekiʻe no nā kaʻina hana lāʻau lapaʻau nuklea.

ʻO nā inoa inoa ʻē aʻe e komo pū ana me MIBG I-123 a me nā ʻano generic like ʻole i like ka palekana a me ka pono. ʻO ka inoa inoa kikoʻī a kāu kauka e hoʻohana ai e hilinaʻi ana i ka mea i loaʻa ma kāu keʻena lapaʻau a me kā lākou makemake e pili ana i ka ʻike.

Ma waho aʻe o ka inoa inoa, aia nā mana i ʻae ʻia o Iobenguane I-123 i ka mea hana like a hana like. Hoʻohālikelike ʻia ka ʻike iodine radioactive a me nā hiki ke kiʻi ʻia ma nā hoʻomākaukau lāʻau lapaʻau kūpono.

Nā koho ʻē aʻe o Iobenguane I-123

Hiki i kekahi mau ʻano hana kiʻi ʻē aʻe ke hāʻawi i ka ʻike like, ma muli o ka mea a kāu kauka e hoʻāʻo nei e ʻike. Hiki i nā scans CT me ka ʻokoʻa ke hōʻike i kahi a me ka nui o ka maʻi, ʻoiai hāʻawi nā scans MRI i nā kiʻi kikoʻī o nā ʻiʻo palupalu me ka ʻole o ka ʻike ʻana i ka radiation.

No nā ʻano maʻi kikoʻī, kūpono paha nā scans lāʻau lapaʻau nuklea ʻē aʻe. Hiki i nā scans Octreotide (me ka hoʻohana ʻana iā In-111 a i ʻole Ga-68) ke ʻike i kekahi mau maʻi neuroendocrine, ʻoiai hiki i nā scans FDG-PET ke ʻike i nā ʻano maʻi like ʻole e pili ana i kā lākou hana metabolic.

I kekahi mau hihia, hiki i nā kauka ke hoʻohana i ka MIBG I-131 (he mana therapeutic) ma kahi o I-123, ʻoi aku ka nui o ka mālama ʻana ma mua o ke kiʻi ʻana. Eia naʻe, hāʻawi ʻo I-131 i ka nui o ka radiation a koi i nā hana mālama hou aku.

E koho kāu kauka i ke ʻano kiʻi maikaʻi loa e pili ana i kāu mau hōʻailona kikoʻī, ka mōʻaukala olakino, a me ke ʻano o ka ʻike e pono ai lākou e hana i kahi ʻike pololei. I kekahi manawa hoʻohana pū ʻia nā ʻenehana kiʻi he nui e kiʻi i ke kiʻi piha loa.

Ua ʻoi aku ka maikaʻi o Iobenguane I-123 ma mua o nā ʻano hana kiʻi ʻē aʻe?

He maikaʻi loa ka Iobenguane I-123 i ka ʻike ʻana i nā ʻano maʻi maʻi kikoʻī i hiki ʻole i nā ʻano hana kiʻi ʻē aʻe ke ʻike. No nā pheochromocytomas, paragangliomas, a me nā neuroblastomas, ua manaʻo pinepine ʻia ʻo ia ke kūlana gula no ka mea hiki iā ia ke ʻike i nā maʻi maʻi liʻiliʻi ʻaʻole i ʻike maopopo ʻia ma nā scans CT a i ʻole MRI.

I ka hoʻohālikelike ʻana me nā scans CT a i ʻole MRI maʻamau, hāʻawi ka Iobenguane I-123 i ka ʻike hana e pili ana i ka hana ʻana o nā ʻiʻo, ʻaʻole wale nō ke ʻano o lākou. ʻO ia hoʻi, hiki iā ia ke ʻike i nā wahi pilikia ma mua o ka nui e ʻike ʻia ma nā kiʻi structural.

Eia naʻe, ʻaʻole maikaʻi mau kēia ʻano hana kiʻi ma mua o nā mea ʻē aʻe. Hāʻawi nā scans CT a me MRI i ka ʻike anatomical kikoʻī a hiki ke ʻike i nā ʻano maʻi like ʻole. ʻAʻole lākou e pili ana i ka ʻike ʻana i ka radiation, kahi e makemake ai lākou no ka nānā maʻamau ʻana i kekahi mau maʻi.

Aia ke koho ʻana ma waena o nā ʻano hana kiʻi i ka mea a kāu kauka e manaʻo ai a me ka ʻike e pono ai lākou. ʻO ka pinepine, hoʻohana ʻia ka Iobenguane I-123 me nā ʻenehana kiʻi ʻē aʻe e hāʻawi i ke kiʻi diagnostic piha loa.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Iobenguane I-123

He Palekana anei ka Iobenguane I-123 no ka poʻe me ka maʻi diabetes?

ʻAe, palekana ka Iobenguane I-123 no ka poʻe me ka maʻi diabetes. ʻAʻole pili pololei ka lāʻau lapaʻau i nā pae kōpaʻa koko a i ʻole e launa pū me ka hapa nui o nā lāʻau lapaʻau diabetes. Eia naʻe, pono ʻoe e hoʻomau i ka lawe ʻana i kāu mau lāʻau lapaʻau diabetes e like me ke kau ʻia a nānā i kāu kōpaʻa koko maʻamau.

Inā ʻoe e lawe i ka metformin no ka maʻi diabetes, hiki i kāu kauka ke hoʻomaha i kēia lāʻau lapaʻau i ka manawa o kāu haʻawina kiʻi. ʻAʻole pili kēia mālama ʻana i ka Iobenguane I-123 ponoʻī, akā e hōʻemi i nā pilikia e pili ana i ka puʻupaʻa mai ka ʻokoʻa a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe āu e loaʻa ai.

He aha kaʻu e hana ai inā hoʻohana au i ka nui o ka Iobenguane I-123?

ʻAʻole hiki ke loaʻa ka nui o ka Iobenguane I-123 ma muli o ka hāʻawi ʻia ʻana o ka lāʻau lapaʻau e nā poʻe loea olakino i aʻo ʻia ma nā wahi lapaʻau i mālama ʻia. Hoʻohālikelike ʻia ka mahele ma muli o kou kaumaha kino a me nā koi kiʻi kūikawā.

Inā hopohopo ʻoe no ka loaʻa ʻana o ka nui o ka lāʻau lapaʻau, e hoʻomanaʻo i nā keʻena lāʻau lapaʻau nukelea i nā protocol koʻikoʻi no ka hoʻomākaukau ʻana a me ka lawelawe ʻana i ka mahele. Ana pololei ʻia a nānā ʻia ka nui āu e loaʻa ai i ke kaʻina holoʻokoʻa.

Inā loaʻa iā ʻoe kekahi mau hōʻailona maʻamau ma hope o kāu injection, e hoʻokaʻaʻike koke i kāu mea mālama ola. Hiki iā lākou ke loiloi inā pili kāu mau hōʻailona i ka lāʻau lapaʻau a hāʻawi i ka mālama kūpono inā pono.

He aha kaʻu e hana ai inā e hala wau i ka mahele o Iobenguane I-123?

No ka mea, hāʻawi ʻia ka Iobenguane I-123 ma ke ʻano he injection hoʻokahi no nā haʻawina kiʻi kūikawā, ʻaʻohe mea e like me ka

E hala ka hapa nui o ka radioaktivity mai kou kino i loko o 24 a 48 mau hola ma hope o ka hoʻokomo ʻana. Hiki iā ʻoe ke kōkua i ka wikiwiki ʻana i kēia kaʻina hana ma ka inu ʻana i nā wai nui a me ka mimi pinepine ʻana, e kōkua ana i ka holoi ʻana i ka lāʻau lapaʻau mai kou ʻōnaehana.

E hāʻawi kāu kauka i nā ʻōlelo kikoʻī e pili ana i nā hana e pono ai ʻoe e hana i nā lā mua ma hope o ka hoʻokomo ʻana, e like me ka kaupalena ʻana i ka pilina pili me nā wahine hāpai a i ʻole nā keiki liʻiliʻi ma ke ʻano he palekana.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o Iobenguane I-123?

Hiki i ka hapa nui o nā kānaka ke kalaiwa palekana ma hope o ka loaʻa ʻana o Iobenguane I-123, no ka mea, ʻaʻole pinepine ka lāʻau lapaʻau i nā hopena ʻaoʻao e hoʻopilikia i ka hiki ke kalaiwa. Eia naʻe, hiki i kekahi poʻe ke ʻike i ka ʻūlū māmā a i ʻole ka nausea ma hope koke o ka hoʻokomo ʻana.

He manaʻo maikaʻi e loaʻa i kekahi e kalaiwa iā ʻoe i ka manawa a me ka manawa mai kāu manawa, ʻoiai inā ʻoe e hopohopo nei e pili ana i ke kaʻina hana a i ʻole ʻoe e ʻike i nā hopena ʻaoʻao. Hāʻawi pū kēia iā ʻoe i ka maluhia o ka noʻonoʻo a hiki iā ʻoe ke hoʻomaha inā pono.

Inā manaʻo ʻoe he maʻamau loa ma hope o kāu hoʻokomo ʻana a me ke kiʻi ʻana, palekana ka kalaiwa. Eia naʻe, e hahai mau i nā ʻōlelo kikoʻī a kāu kauka a mai kalaiwa inā ʻoe e ʻūlū, nausea, a i ʻole maikaʻi ʻole.