He aha ʻo Lasmiditan: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau hou ʻo Lasmiditan i kuhikuhi ʻia e mālama i nā ʻeha poʻo migraine i nā pākeke. No ka papa o nā lāʻau i kapa ʻia he selective serotonin receptor agonists, e hana ana i nā ʻano like ʻole mai nā lāʻau migraine kuʻuna ma ka hoʻopaʻa ʻana i nā mea hoʻokipa lolo kūikawā e pili ana i ka ʻeha migraine.

Hāʻawi kēia lāʻau lapaʻau i ka manaʻolana no ka poʻe i loaʻa ʻole ka hoʻomaha me nā lāʻau migraine ʻē aʻe a i ʻole ka poʻe hiki ʻole ke lawe i kekahi mau lāʻau migraine ma muli o nā maʻi puʻuwai. ʻO ka hoʻomaopopo ʻana i ka hana ʻana o ka lasmiditan a me ka mea e manaʻo ai hiki ke kōkua iā ʻoe e hana i nā hoʻoholo i ʻike ʻia e pili ana i kāu mālama migraine.

He aha ʻo Lasmiditan?

He lāʻau lapaʻau ʻo Lasmiditan i kuhikuhi ʻia e mālama i nā hōʻeha migraine nui me ka ʻole a i ʻole ka aura i nā pākeke. ʻAʻole like me kekahi mau lāʻau migraine kahiko, ʻaʻole ia e pili i nā kīʻaha koko i kou puʻuwai, e lilo ia i koho palekana no ka poʻe me kekahi mau maʻi cardiovascular.

Hana ka lāʻau ma ka hoʻāla ʻana i nā mea hoʻokipa serotonin kūikawā i kou lolo i kapa ʻia ʻo 5-HT1F receptors. He kuleana koʻikoʻi kēia mau mea hoʻokipa i nā ala ʻeha migraine. Ke hoʻopaʻa ʻo lasmiditan i kēia mau mea hoʻokipa, kōkua ia i ka hōʻemi ʻana i ka mumū a me nā hōʻailona ʻeha e hana i kāu mau hōʻailona migraine.

Hiki paha iā ʻoe ke ʻike i ka lasmiditan ma kona inoa inoa, Reyvow. Ua ʻae ʻia e ka FDA i ka makahiki 2019 ma ke ʻano he lāʻau mua i kona papa, e hōʻike ana i kahi holomua nui i nā koho lapaʻau migraine.

No ke aha i hoʻohana ʻia ai ʻo Lasmiditan?

Hoʻohana kūikawā ʻia ʻo Lasmiditan e mālama i nā hōʻeha migraine nui i nā pākeke. ʻO ia hoʻi, ua hoʻolālā ʻia e hoʻōki i ka migraine i hoʻomaka mua ʻia, ma mua o ka pale ʻana i nā migraines e hiki mai ana.

Hiki i kāu kauka ke kuhikuhi i ka lasmiditan inā loaʻa iā ʻoe nā ʻeha poʻo migraine mai ka waena a i ke koʻikoʻi e keakea i kāu mau hana i kēlā me kēia lā. Hiki iā ia ke kōkua me ka ʻeha poʻo, ka nausea, a me ka naʻau i ka mālamalama a me ke kani e hele pinepine me nā migraines.

He mea nui kēia lāʻau lapaʻau no ka poʻe i loaʻa i ka maʻi puʻuwai, ke koko kiʻekiʻe, a i ʻole nā ​​maʻi cardiovascular ʻē aʻe e hoʻopilikia ai i nā lāʻau triptan kuʻuna. He koho nō hoʻi inā ua hoʻāʻo ʻoe i nā lāʻau lapaʻau migraine ʻē aʻe me ka holomua ʻole a i ʻole i loaʻa nā hopena ʻaoʻao e hoʻopilikia ana.

Pehea e hana ai ʻo Lasmiditan?

Hana ʻo Lasmiditan ma ka ʻimi ʻana i nā mea hoʻokipa serotonin kikoʻī i loko o kou lolo i kapa ʻia ʻo 5-HT1F receptors. Ke hoʻomaka ka migraine, lilo kekahi mau ala ʻeha i mea hana nui, e hoʻouna ana i nā hōʻailona ʻeha nui i loko o kou poʻo a me ka hoʻoulu ʻana i nā hōʻailona ʻē aʻe e like me ka nausea.

Ma ka hoʻopaʻa ʻana i kēia mau mea hoʻokipa, kōkua ʻo lasmiditan i ka hoʻomaha ʻana i nā ala nerve overactive e hana ai i ka ʻeha migraine. Hoʻemi pū ia i ka mumū i loko o ka ʻiʻo lolo e kōkua ana i nā hōʻailona migraine. Kōkua kēia ʻano hana i ka hoʻopau ʻana i ke kaʻina migraine ke hoʻomaka.

Ua manaʻo ʻia ka lāʻau lapaʻau he ikaika a hoʻomaka maʻamau i loko o ʻelua hola o ka lawe ʻana. ʻAʻole like me kekahi mau lāʻau lapaʻau migraine e hoʻopili i nā kīʻaha koko, ʻaʻole pili nui ʻo lasmiditan i kāu ʻōnaehana cardiovascular, e palekana ai no ka poʻe me nā maʻi puʻuwai.

Pehea e lawe ai au iā Lasmiditan?

E lawe iā lasmiditan e like me ke kauoha a kāu kauka, maʻamau ma ke ʻano he hoʻokahi mahele ke manaʻo ʻoe e hoʻomaka ana ka migraine. Hiki iā ʻoe ke lawe me ka ʻole o ka meaʻai, ʻoiai ʻo ka lawe ʻana me ka meaʻai e kōkua paha i ka hōʻemi ʻana i ka ʻōpū inā loaʻa iā ʻoe ka nausea.

E ale i ka papa holoʻokoʻa me ke aniani wai piha. Mai ʻoki, wāwahi, a nau paha i ka papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka lawe ʻia ʻana o ka lāʻau. ʻO ka mahele hoʻomaka maʻamau he 50mg, ʻoiai paha e kauoha kāu kauka i 100mg inā pono.

He mea nui e lawe i ka lasmiditan i ka wā e ʻike ai ʻoe i nā hōʻailona migraine e hoʻomaka ana. ʻOi aku ka maikaʻi o ka lāʻau lapaʻau ke lawe ʻia i ka wā mua o ke kaʻina migraine, ma mua o ka lilo ʻana o ka ʻeha i mea nui. Inā ʻaʻole e hoʻomaikaʻi kou migraine ma hope o ʻelua hola, mai lawe i ka lua o ka lāʻau me ka ʻole e kūkākūkā mua i kāu kauka.

Pehea ka lōʻihi e lawe ai au i ka Lasmiditan?

Hoʻolālā ʻia ka Lasmiditan no ka hoʻohana ʻana i ka wā pōkole e mālama i nā hōʻeha migraine, ʻaʻole no ka pale ʻana i kēlā me kēia lā. Pono ʻoe e lawe wale i ka wā e loaʻa ana iā ʻoe kahi migraine maoli, ʻaʻole ma ke ʻano he hana pale.

Hāʻawi maʻamau ka lāʻau lapaʻau i ka hōʻoluʻolu i loko o ʻelua hola, a hiki i kāna mau hopena ke hala i 24 mau hola. ʻAʻole pono ʻoe e lawe ma mua o hoʻokahi lāʻau i loko o kahi manawa 24-hola ke ʻole i kuhikuhi ʻia e kāu kauka. ʻO ka lawe pinepine ʻana hiki ke alakaʻi i nā poʻo poʻo overuse lāʻau.

Inā ʻike ʻoe iā ʻoe iho e pono ana i ka lasmiditan ma mua o 10 mau lā i kēlā me kēia mahina, e kamaʻilio me kāu kauka e pili ana i nā lāʻau lapaʻau migraine pale. Hiki i ka hoʻohana pinepine ʻana i nā lāʻau lapaʻau migraine acute i kekahi manawa ke hoʻonui i nā poʻo poʻo i ka manawa, no laila he mea nui e hoʻohana iā lākou e like me ke kuhikuhi.

He aha nā hopena ʻaoʻao o Lasmiditan?

E like me nā lāʻau lapaʻau a pau, hiki i ka lasmiditan ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole i loaʻa i nā mea a pau. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a he manawa pōkole, e hoʻoponopono ana i ka wā e haʻalele ai ka lāʻau lapaʻau i kāu ʻōnaehana.

Eia nā hopena ʻaoʻao i hōʻike pinepine ʻia e hiki iā ʻoe ke ʻike:

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• ʻO ka noʻonoʻo ʻole a i ʻole ka manaʻo māmā
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• Ka hiamoe a i ʻole ka luhi
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• ʻO ka nausea a i ʻole ka ʻoluʻolu o ka ʻōpū
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• ʻO ka nāwaliwali o ka ʻiʻo a i ʻole ka manaʻo paʻa ʻole
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• ʻO ka ʻūlū a i ʻole ka ʻehaʻeha i nā lima a i ʻole nā wāwae
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• Waha maloʻo
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• Ka manaʻo i hoʻokaʻawale ʻia a i ʻole

  ʻO kēia mau hopena ʻaoʻao maʻamau e hoʻomaikaʻi maʻamau i loko o kekahi mau hola i ka wā e hana ai kou kino i ka lāʻau. Hiki ke ʻike nui ʻia ka wili a me ka hiamoe, ʻo ia ke kumu ʻaʻole pono ʻoe e kalaiwa a i ʻole e hana i nā mīkini no ka liʻiliʻi o ʻewalu hola ma hope o ka lawe ʻana i ka lasmiditan.

  ʻO nā hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e koi ana i ka lāʻau lapaʻau koke, e komo pū ana me:

  • ʻO ka wili nui a i ʻole ka hāʻule
  • He paʻakikī ka hanu ʻana a i ʻole ka paʻa o ka umauma
  • ʻO ka nāwaliwali o ka ʻiʻo nui
  • Huikau a i ʻole disorientation
  • Nā hopena maʻi e like me ka ʻōpala, ka ʻūlū, a i ʻole ka pehu

  Inā ʻike ʻoe i kekahi o kēia mau hopena ʻaoʻao koʻikoʻi, e hoʻokaʻaʻike koke i kāu mea mālama ola a i ʻole e ʻimi i ka lāʻau lapaʻau pilikia. ʻOiai he kakaʻikahi, hiki i kēia mau hōʻailona ke hōʻike i kahi hopena koʻikoʻi e pono ai ka lāʻau lapaʻau wikiwiki.

  ʻO wai ka mea ʻaʻole pono e lawe i ka Lasmiditan?

  ʻAʻole kūpono ka Lasmiditan no nā mea a pau, a ʻo kekahi mau maʻi a i ʻole nā kūlana e palekana ʻole ai ka hoʻohana ʻana. E nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana i kēia lāʻau.

  ʻAʻole pono ʻoe e lawe i ka lasmiditan inā loaʻa iā ʻoe ka maʻi ate koʻikoʻi, no ka mea, ʻaʻole hiki i kou kino ke hana pono i ka lāʻau. Pono nō hoʻi ka poʻe me ka mōʻaukala o ka hahau ʻana, ka puʻuwai, a i ʻole kekahi mau maʻi cardiovascular koʻikoʻi ʻē aʻe e pale i kēia lāʻau.

  Eia nā kūlana nui a me nā kūlana kahi i ʻōlelo ʻole ʻia ai ka lasmiditan:

  • ʻO ka maʻi ate koʻikoʻi a i ʻole ka ʻole o ka ate
  • ʻO ka hahau mua a i ʻole ka hoʻouka ischemic transient (TIA)
  • Mōʻaukala o ka puʻuwai a i ʻole nā pilikia puʻuwai koʻikoʻi
  • ʻO ke koko kiʻekiʻe ʻole
  • Hāpai a i ʻole ka hānai ʻana
  • Makahiki ma lalo o 18 mau makahiki
  • Nā maʻi i ʻike ʻia i ka lasmiditan a i ʻole kāna mau meaʻai

  Eia kekahi, pono ʻoe e akahele inā he pilikia kou puʻupaʻa, e lawe i kekahi mau lāʻau anti-depressant, a i ʻole he moʻolelo o ka hoʻohana ʻana i nā mea ʻino. Hiki ke hoʻonui ʻia nā hopena hoʻomaha o ka lasmiditan e ka waiʻona a i ʻole nā mea hoʻohaʻahaʻa ʻē aʻe o ka ʻōnaehana nerve waena, no laila e pale i kēia mau hui.

Inoa Brand Lasmiditan

Kūʻai ʻia ʻo Lasmiditan ma lalo o ka inoa brand Reyvow ma ʻAmelika Hui Pū ʻIa. Hana ʻia kēia lāʻau lapaʻau inoa brand e Eli Lilly and Company a ua ʻae mua ʻia e ka FDA i ʻOkakopa 2019.

Loaʻa ʻo Reyvow i ʻelua ikaika: 50mg a me 100mg papa. Loaʻa i nā ikaika ʻelua ka mea hana like, lasmiditan, akā i nā nui like ʻole e hiki ai ke hoʻopilikino i ka dosage e pili ana i kāu mau pono kikoʻī a me ka pane ʻana i ka lāʻau lapaʻau.

I kēia manawa, ʻaʻohe mana generic o lasmiditan i loaʻa, no ka mea, aia nō ka lāʻau lapaʻau ma lalo o ka pale patent. ʻO ia hoʻi, ʻo Reyvow wale nō ka brand i loaʻa, hiki ke lilo i mea ʻoi aku ka pipiʻi ma mua o nā lāʻau migraine kahiko i loaʻa nā koho generic.

Nā Koho Lasmiditan

Inā ʻaʻole kūpono ʻo lasmiditan iā ʻoe a i ʻole ʻaʻole hāʻawi i ka hoʻomaha kūpono, aia kekahi mau koho lapaʻau migraine ʻē aʻe. Hiki i kāu kauka ke kōkua iā ʻoe e ʻimi i ke koho maikaʻi loa e pili ana i kāu mōʻaukala olakino a me nā pono.

Hoʻāʻo pinepine ʻia nā lāʻau triptan kuʻuna e like me sumatriptan (Imitrex), rizatriptan (Maxalt), a me zolmitriptan (Zomig) i ka mua. Hana kēia mau lāʻau lapaʻau ma ka hoʻopaʻa ʻana i nā kīʻaha koko i ka lolo a he mea maikaʻi ia no ka nui o nā kānaka, ʻoiai ʻaʻole kūpono lākou no ka poʻe me nā maʻi puʻuwai.

Eia nā mahele nui o nā koho lapaʻau migraine:

• Triptans (sumatriptan, rizatriptan, eletriptan)
• CGRP receptor antagonists (ubrogepant, rimegepant)
• Ergot alkaloids (dihydroergotamine)
• Nā lāʻau anti-nausea (metoclopramide, ondansetron)
• Nā mea hoʻomaha ʻeha (ibuprofen, naproxen, acetaminophen)
• Nā lāʻau hui (sumatriptanaproxen)

ʻO nā koho hou e like me ubrogepant (Ubrelvy) a me rimegepant (Nurtec ODT) e hana like me lasmiditan ma ka hoʻopaʻa ʻana i nā mea loaʻa like ʻole e pili ana i ka ʻeha migraine. Hiki i kēia mau mea kūʻē CGRP ke lilo i mau koho maikaʻi inā ʻaʻole hiki iā ʻoe ke lawe i ka lasmiditan akā pono ʻoe i kahi koho palekana cardiovascular.

Ua ʻoi aku ka maikaʻi o Lasmiditan ma mua o Sumatriptan?

He mau lāʻau lapaʻau migraine maikaʻi ʻo Lasmiditan a me sumatriptan, akā hana lākou i nā mea like ʻole a loaʻa nā pono like ʻole e pili ana i kou kūlana pilikino. ʻAʻole ʻoi aku ka maikaʻi o kekahi ma mua o kekahi, no ka mea, ʻo ke koho maikaʻi loa e pili ana i kāu ʻikepili olakino a me ka pane ʻana i ka lāʻau lapaʻau.

Ua loaʻa ʻo Sumatriptan no ka lōʻihi a loaʻa ka noiʻi nui e kākoʻo ana i kona pono. Hoʻāʻo pinepine ʻia i ka mua no ka mea loaʻa ia i nā ʻano like ʻole (nā papa, nā injections, ka ʻehu ihu) a loaʻa nā mana generic e hana ai i mea kūʻai. Eia naʻe, hiki i ka sumatriptan ke hoʻopili i nā kīʻaha koko, e lilo ia i mea kūpono ʻole no ka poʻe me nā maʻi puʻuwai.

ʻO ka pōmaikaʻi nui o Lasmiditan ʻo ia kona palekana no ka poʻe me nā maʻi cardiovascular. ʻAʻole ia e pili i nā kīʻaha koko i ka puʻuwai, e lilo ia i koho palekana inā loaʻa iā ʻoe ka maʻi puʻuwai, ke koko kiʻekiʻe, a i ʻole nā pilikia cardiovascular ʻē aʻe. Hiki nō hoʻi ke kumu i nā headaches rebound liʻiliʻi me ka hoʻohana pinepine.

ʻO ke koho ma waena o kēia mau lāʻau lapaʻau e pili pinepine ana i kāu ʻikepili olakino. Inā loaʻa iā ʻoe nā maʻi puʻuwai, ʻo lasmiditan paha ke koho maikaʻi loa. Inā ʻaʻohe ou hopohopo cardiovascular a he mea nui ke kumukūʻai, ʻoi aku ka maikaʻi o ka sumatriptan.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Lasmiditan

Ua palekana ʻo Lasmiditan no ka poʻe me ka maʻi puʻuwai?

ʻAe, ua manaʻo ʻia ʻo lasmiditan he palekana no ka poʻe me ka maʻi puʻuwai i hoʻohālikelike ʻia me nā lāʻau lapaʻau migraine kuʻuna e like me triptans. ʻAʻole like me triptans, ʻaʻole hoʻopili nui ʻo lasmiditan i nā kīʻaha koko i ka puʻuwai, e hōʻemi ana i ka pilikia o nā pilikia cardiovascular.

Akā, pono nō ʻoe e kūkākūkā i kou maʻi puʻuwai me kāu kauka ma mua o ka hoʻomaka ʻana i ka lasmiditan. ʻOiai he palekana ia no ka hapa nui o nā maʻi puʻuwai, hiki i kekahi mau maʻi cardiovascular koʻikoʻi ke hana ʻole ia. E loiloi kāu kauka i kāu mau mea pilikia pilikino a e hoʻoholo inā kūpono ka lasmiditan no kou kūlana.

He aha kaʻu e hana ai inā ua hoʻohana hewa au i ka nui o ka Lasmiditan?

Inā ua lawe hewa ʻoe i ka nui o ka lasmiditan ma mua o ka mea i kauoha ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau make. ʻO ka lawe ʻana i ka nui hiki ke hoʻonui i kou pilikia o nā hopena ʻaoʻao koʻikoʻi e like me ka ʻūlū nui, ka hiamoe nui, a i ʻole ka pilikia o ka hanu.

Mai hoʻāʻo e hoʻokele iā ʻoe iho e kiʻi i ke kōkua, no ka mea, hiki i ka lāʻau lapaʻau ke hoʻoulu i ka hiamoe a me ka ʻūlū. E noi i kekahi e hoʻokele iā ʻoe i ka lumi pilikia inā ʻōlelo ʻia e kāu mea mālama ola. E lawe mai i ka hue lāʻau lapaʻau me ʻoe i hiki i nā limahana lapaʻau ke ʻike pono i ka mea a me ka nui āu i lawe ai.

Hiki i nā hōʻailona o ka overdose ke komo i ka luhi nui, ka huikau, ka pilikia o ka noho ʻana i ka makaʻala, a i ʻole nā pilikia me ka hoʻonohonoho. ʻOiai inā maikaʻi ʻoe i ka wā mua, he mea nui e ʻimi i ka lāʻau lapaʻau, no ka mea, ʻaʻole paha e ʻike koke ʻia kekahi mau hopena.

He aha kaʻu e hana ai inā ua hala au i kahi mahele o Lasmiditan?

Lawe ʻia ka Lasmiditan i ka wā e loaʻa ai iā ʻoe ka migraine, ʻaʻole ma kahi papa manawa maʻamau, no laila ʻaʻole hiki iā ʻoe ke

Inā ʻaʻole ʻoe i maopopo inā e lawe i ka lasmiditan no ka migraine i hala no kekahi manawa, e launa me kāu mea mālama ola no ke alakaʻi. Hiki iā lākou ke kōkua iā ʻoe e hoʻoholo inā he mea kūpono ke lawe ʻana a i ʻole he mea kūpono paha nā lāʻau lapaʻau ʻē aʻe i kēlā manawa.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Lasmiditan?

Hiki iā ʻoe ke hooki i ka lawe ʻana i ka lasmiditan i kēlā me kēia manawa, no ka mea, ʻaʻole ia he lāʻau lapaʻau e koi ai i ka hoʻōki ʻana. No ka mea, hoʻohana ʻia ia no nā hōʻeha migraine pākahi ma mua o ka pale ʻana i kēlā me kēia lā, ʻaʻohe pilikia o nā hōʻailona haʻalele ke hooki ʻoe.

Hiki iā ʻoe ke koho e hooki i ka hoʻohana ʻana i ka lasmiditan inā ʻike ʻoe i nā lāʻau lapaʻau ʻē aʻe i ʻoi aku ka maikaʻi, inā ʻike ʻoe i nā hopena ʻaoʻao e hoʻopilikia ana, a i ʻole inā e emi pinepine a koʻikoʻi paha kāu migraines. Hoʻōki kekahi poʻe i ka wā e hoʻomaka ai lākou i nā lāʻau lapaʻau migraine pale e hōʻemi ana i ko lākou pono no nā lāʻau lapaʻau acute.

Ma mua o ka hooki ʻana, e kūkākūkā i kāu hoʻoholo me kāu kauka, ʻoiai inā ua kōkua ka lasmiditan i kāu migraines. Hiki iā lākou ke kōkua i ka hōʻoia ʻana he mau koho lapaʻau ʻē aʻe kāu a hiki ke hōʻike i nā ala ʻē aʻe e mālama ai i kou maʻi migraine.

Hiki iaʻu ke lawe i ka Lasmiditan me nā lāʻau lapaʻau ʻē aʻe?

Hiki i ka Lasmiditan ke launa pū me kekahi mau lāʻau lapaʻau, no laila he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau a pau, nā lāʻau lapaʻau ma luna o ka pāʻani, a me nā mea hoʻohui āu e lawe nei. Hiki i kekahi mau hui ke hoʻonui i nā hopena ʻaoʻao a i ʻole e hōʻemi i ka pono.

Hiki i ka lāʻau lapaʻau ke hoʻonui i nā hopena sedating o ka waiʻona, nā lāʻau hiamoe, nā lāʻau hopohopo, a me kekahi mau antidepressants. Hiki i kēia hui ke hoʻoluhi nui iā ʻoe a i ʻole ka ʻūlū, e hoʻonui ana i kou pilikia o ka hāʻule a i ʻole nā ​​pōʻino. Hiki i kāu kauka ke ʻōlelo e pale i kēia mau hui a i ʻole e hoʻoponopono i nā mea.

E nīnau mau i kāu mea mālama ola ma mua o ka hoʻomaka ʻana i nā lāʻau lapaʻau hou i ka wā e hoʻohana ana i ka lasmiditan. Hiki iā lākou ke nānā i nā pilina kūpono a kōkua iā ʻoe e mālama palekana i kāu mau lāʻau lapaʻau a pau. E mālama i kahi papa inoa hou o kāu mau lāʻau lapaʻau a pau e kaʻana like me nā mea mālama ola āu e ʻike ai.