He aha ʻo Linagliptin a me Metformin: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Linagliptin a me metformin he lāʻau hui e kōkua ana i ka poʻe me ka maʻi diabetes type 2 e mālama pono i ko lākou pae kōpaʻa koko. Hoʻohui kēia lāʻau hana pālua i ʻelua mau lāʻau lapaʻau diabetes i hōʻoia ʻia i loko o hoʻokahi pila maʻalahi, e maʻalahi ai iā ʻoe ke pili i kāu hoʻolālā lapaʻau ʻoiai e loaʻa ana ka mana kōpaʻa koko maikaʻi aʻe ma mua o ka lāʻau lapaʻau hoʻokahi.

He aha ʻo Linagliptin a me Metformin?

Aia i loko o kēia lāʻau hui ʻelua mau lāʻau lapaʻau diabetes like ʻole e hana pū ana e hoʻohaʻahaʻa i kou kōpaʻa koko. No ka hui ʻo DPP-4 inhibitors ʻo Linagliptin, ʻoiai ʻo metformin mai ka ʻohana biguanide o nā lāʻau diabetes.

E noʻonoʻo i kēia mau lāʻau lapaʻau ʻelua ma ke ʻano he mau hoa hui me nā ikaika like ʻole. Kōkua ʻo Metformin i kou kino e hoʻohana maikaʻi i ka insulin a hoʻemi i ka nui o ke kō e hana ai kou ate. Hana ʻo Linagliptin ma ke kōkua ʻana i kou pancreas e hoʻokuʻu i ka insulin hou aʻe ke kiʻekiʻe kou kōpaʻa koko a hoʻemi i nā hormones e hoʻonui ai i ke kōpaʻa koko.

Hiki i kāu kauka ke kuhikuhi i kēia hui ʻana ke lawa ʻole ka metformin wale nō i ka mālama ʻana i kou kōpaʻa koko i ka pae i manaʻo ʻia. ʻOi aku ka maikaʻi o ke ala hui ma mua o ka lawe ʻana i kekahi lāʻau lapaʻau, e hāʻawi ana iā ʻoe i ka mālama kōpaʻa koko piha.

No ke aha e hoʻohana ʻia ai ʻo Linagliptin a me Metformin?

Hoʻolālā ʻia kēia lāʻau lapaʻau e mālama i ka maʻi diabetes type 2 i nā pākeke. Ua kuhikuhi ʻia ke ʻai a me ka hoʻoikaika kino wale nō ʻaʻole lawa e mālama i kou pae kōpaʻa koko i loko o kahi pae olakino.

Hiki i kāu kauka ke ʻōlelo aku i kēia hui inā e lawe ana ʻoe i ka metformin akā pono ʻoe i ka mana kōpaʻa koko hou. Hoʻohana ʻia nō hoʻi i ka hoʻomaka ʻana i ka mālama ʻana i ka maʻi diabetes no ka poʻe e pōmaikaʻi mai nā lāʻau lapaʻau ʻelua mai ka hoʻomaka.

ʻO ka pahuhopu ke kōkua i ka mālama ʻana i kāu hemoglobin A1C (he ana o ke kō koko maʻamau ma luna o 2-3 mahina) ma lalo o 7% no ka hapa nui o nā mākua. Hiki i kēia hui ʻana ke kōkua nui inā ua paʻakikī ʻoe i ka hiki ʻana i kāu mau pahuhopu kō koko me nā loli ola a me nā lāʻau lapaʻau hoʻokahi.

Pehea e hana ai ʻo Linagliptin a me Metformin?

Hana kēia hui ʻana i nā lāʻau lapaʻau ma o nā ala ʻelua like ʻole e hāʻawi iā ʻoe i ka mana kō koko maikaʻi aʻe. Ua manaʻo ʻia he lāʻau lapaʻau maʻi diabetes ikaika e pili ana i nā ʻano like ʻole o ka mālama ʻana i ke kō koko.

Hana nui ʻo Metformin ma ka hoʻolilo ʻana i kāu mau cell muscle i ʻoi aku ka naʻau i ka insulin, no laila hiki iā lākou ke hoʻohana i ka glucose ʻoi aku ka maikaʻi. Hōʻike pū ia i kou ate e hana i ka glucose liʻiliʻi, ʻoi aku hoʻi ma waena o nā meaʻai a me ka pō ke ʻaʻole ʻoe e ʻai.

Hana ʻo Linagliptin me ka ʻōnaehana hormone maoli o kou kino. Ke piʻi ke kō koko ma hope o ka ʻai ʻana, kōkua ia i kou pancreas e hoʻokuʻu i ka insulin hou. I ka manawa like, hoʻemi ia i ka hoʻokuʻu ʻana o ka glucagon, he hormone e hoʻonui i ke kō koko ke pono ʻole ʻoe.

ʻO ka hui pū ʻana, hāʻawi kēia mau hana i ka mana kō koko ʻoi aku ka piha ma mua o kekahi lāʻau lapaʻau wale nō. He mea maikaʻi loa ka hui ʻana no ka mea e pili ana i nā pilikia kūʻē i ka insulin a me ka hana ʻana o ka insulin i maʻamau i ka maʻi diabetes type 2.

Pehea wau e lawe ai iā Linagliptin a me Metformin?

E lawe i kēia lāʻau lapaʻau e like me ke kauoha a kāu kauka, maʻamau ʻelua i ka lā me nā meaʻai. ʻO ka lawe ʻana me ka meaʻai e kōkua i ka hōʻemi ʻana i ka ʻōpū a kōkua i kou kino e komo pono i ka lāʻau lapaʻau.

E ale i nā papa holoʻokoʻa me ke aniani wai piha. Mai ʻoki, nau, a i ʻole e wāwahi i nā papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka hoʻokuʻu ʻia ʻana o ka lāʻau lapaʻau i loko o kou kino. Inā pilikia ʻoe i ka ale ʻana i nā pila, e kamaʻilio me kāu kauka e pili ana i nā koho ʻē aʻe.

E hoʻāʻo e lawe i kāu mau lāʻau i nā manawa like i kēlā me kēia lā, e like me ka ʻaina kakahiaka a me ka ʻaina ahiahi. Kōkua kēia i ka mālama ʻana i nā pae paʻa o ka lāʻau lapaʻau i loko o kou kino a maʻalahi hoʻi e hoʻomanaʻo i kāu mau lāʻau.

E hoʻomau i ka ʻai ʻana i ka meaʻai olakino a me ka hoʻoikaika kino e like me ka ʻōlelo a kāu hui mālama ola. ʻOi aku ka maikaʻi o ka lāʻau lapaʻau ke hui pū ʻia me kēia mau ʻano nohona, ʻaʻole ma ke ʻano he pani no lākou.

Pehea ka lōʻihi e lawe ai au i ka Linagliptin a me Metformin?

He lāʻau lapaʻau lōʻihi kēia āu e lawe ai no ka lōʻihi e mālama pono ana i kāu maʻi diabetes. He maʻi maʻi maʻi ʻo Type 2 diabetes e koi pinepine i ka mālama mau ʻana e mālama i nā pae kōpaʻa koko olakino.

E nānā kāu kauka i kāu kaohi kōpaʻa koko maʻamau ma o nā hoʻokolohua A1C, maʻamau i kēlā me kēia 3-6 mahina. Inā e hana maikaʻi ana ka lāʻau lapaʻau a ʻaʻole ʻoe e ʻike i nā hopena ʻaoʻao pilikia, e hoʻomau paha ʻoe i ka lawe ʻana iā ia no ka manawa pau ʻole.

Pono paha kekahi poʻe i nā hoʻoponopono lāʻau a i ʻole nā lāʻau lapaʻau hou aʻe i ka wā e holomua ai kā lākou maʻi diabetes. He mea maʻamau kēia a ʻaʻole ia he manaʻo ʻaʻole e hana ana ka lāʻau lapaʻau. E hana pū kāu hui mālama ola me ʻoe e hoʻoponopono i kāu hoʻolālā lapaʻau e like me ka mea e pono ai.

Mai hooki i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole e kamaʻilio mua me kāu kauka. ʻO ka hooki ʻana i ka lāʻau lapaʻau hiki ke hoʻonui i kou kōpaʻa koko i nā pae weliweli, ʻoiai inā maikaʻi ʻoe.

He aha nā hopena ʻaoʻao o Linagliptin a me Metformin?

ʻO ka hapa nui o nā kānaka e ʻae maikaʻi i kēia hui pū ʻana o ka lāʻau lapaʻau, akā e like me nā lāʻau lapaʻau a pau, hiki iā ia ke hana i nā hopena ʻaoʻao. ʻO ka nūhou maikaʻi, he maʻalahi ka nui o nā hopena ʻaoʻao a hoʻomaikaʻi pinepine i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia nā pilikia e pili ana i ka ʻōpū e maʻalahi ke mālama ʻia me ka manawa kūpono a me ka ʻai ʻana i ka meaʻai:

• Ka luaʻi ʻana a i ʻole ka ʻōpū ʻino, ʻoiai i ka wā e hoʻomaka ai
• Ka maʻi palahē a i ʻole nā noho palupalu
• Ke kinoea a i ʻole ka pehu ʻana
• He ʻono metala i loko o kou waha
• Ua emi ka ʻai
• Ke poʻo

Hoʻomaikaʻi pinepine kēia mau hopena ʻaoʻao digestive i loko o kekahi mau pule i ka wā e maʻa ai kou kino i ka lāʻau. ʻO ka lawe ʻana i ka lāʻau me ka meaʻai a me ka hoʻomaka ʻana me ka haʻahaʻa haʻahaʻa hiki ke kōkua i ka hōʻemi ʻana i kēia mau hopena.

ʻAʻole maʻamau nā hopena ʻaoʻao koʻikoʻi, akā pono e mālama koke i ka lāʻau. ʻO kēia mau hopena ʻaoʻao kakaʻikahi akā koʻikoʻi e komo pū ana:

• Lactic acidosis (he maʻi kakaʻikahi akā koʻikoʻi e hana ana i ka ʻeha o ka ʻiʻo, nāwaliwali, pilikia i ka hanu ʻana, a me ka luhi ʻole)
• Nā hopena maʻi maʻi koʻikoʻi me ka ʻōpala, ka ʻū, ka pehu ʻana, a i ʻole ka pilikia o ka hanu ʻana
• Pancreatitis (ʻeha ʻōpū nui e hiki ke laha i kou kua)
• Nā hōʻailona o ke kōpaʻa koko haʻahaʻa i ka wā i hui pū ʻia me nā lāʻau lapaʻau maʻi diabetes ʻē aʻe

E kelepona koke i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona koʻikoʻi, no ka mea, pono lākou e mālama koke a i ʻole ka hoʻoponopono ʻana i ka lāʻau.

ʻO wai ka mea pono ʻole e lawe iā Linagliptin a me Metformin?

ʻAʻole kūpono kēia lāʻau lapaʻau no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana. Aia kekahi mau kūlana koʻikoʻi e hiki ke hoʻolilo i kēia lāʻau lapaʻau i mea palekana ʻole iā ʻoe.

ʻAʻole pono ka poʻe me nā pilikia o ka puʻupaʻa e lawe i kēia lāʻau lapaʻau, no ka mea, hiki i ka metformin ke kūkulu i nā pae weliweli i ka wā e hana pono ʻole ai kou puʻupaʻa. E nānā kāu kauka i kāu hana puʻupaʻa ma mua o ka hoʻomaka ʻana i ka lāʻau a me ka wā e lawe ana ʻoe.

Pono nō hoʻi ʻoe e pale i kēia lāʻau lapaʻau inā loaʻa iā ʻoe ka maʻi ate koʻikoʻi, ka puʻuwai ʻole, a i ʻole nā kūlana e hoʻonui ai i kou pilikia o ka lactic acidosis. ʻAʻole pono ka poʻe me ka maʻi diabetes type 1 a i ʻole ka diabetic ketoacidosis e hoʻohana i kēia hui.

Inā ʻoe e hoʻolālā ana i ke ʻoki kino a i ʻole kekahi mau hana lapaʻau, pono paha ʻoe e hooki i kēia lāʻau no kekahi manawa. E haʻi mau i kāu poʻe lawelawe mālama ola e pili ana i nā lāʻau lapaʻau a pau āu e lawe nei, me kēia.

Pono nā wāhine hāpai a me nā wāhine e hānai ana i ka waiū e kūkākūkā i nā lāʻau lapaʻau ʻē aʻe me kā lākou kauka, no ka mea, ʻaʻole i hoʻokumu ʻia ka palekana o kēia hui ʻana i ka wā hāpai.

Nā inoa inoa o Linagliptin a me Metformin

Loaʻa kēia lāʻau hui ma lalo o ka inoa inoa ʻo Jentadueto ma ʻAmelika Hui Pū ʻIa. ʻO ka mana hoʻokuʻu lōʻihi i kapa ʻia ʻo Jentadueto XR, e ʻae ana i ka hoʻohana ʻana i hoʻokahi manawa i ka lā ma kahi o ʻelua manawa i ka lā.

Loaʻa nō hoʻi nā mana generic o kēia hui ʻana, aia nā mea hana like akā ʻoi aku ka liʻiliʻi o ke kumukūʻai ma mua o nā mana inoa inoa. Hiki i kāu kauka lapaʻau ke kōkua iā ʻoe e hoʻomaopopo inā loaʻa kahi mana generic a kūpono iā ʻoe.

Inā ʻoe e lawe i ka inoa inoa a i ʻole ka mana generic, hana like ka lāʻau. E kauoha kāu kauka i ka mana i kūpono loa i kāu kūlana a me ka uhi ʻinikua.

Nā koho ʻē aʻe o Linagliptin a me Metformin

Inā ʻaʻole hana maikaʻi kēia hui ʻana iā ʻoe, aia kekahi mau koho lapaʻau ʻē aʻe. Hiki i kāu kauka ke kōkua iā ʻoe e ʻimi i kahi koho ʻē aʻe e kūpono i kāu pono a me ke kūlana olakino.

Hoʻohui nā lāʻau lapaʻau ʻē aʻe i ka metformin me nā lāʻau maʻi diabetes like ʻole, e like me glipizide (Metaglip), glyburide (Glucovance), a i ʻole pioglitazone (Actoplus Met). Loaʻa i kēlā me kēia hui nā pōmaikaʻi like ʻole a me nā hopena ʻaoʻao.

Hiki nō hoʻi iā ʻoe ke lawe i nā lāʻau lapaʻau pākahi, e ʻae ana i ka maʻalahi o ka hoʻohana ʻana akā pono e lawe i nā pila he nui. Makemake kekahi poʻe i kēia ala inā pono lākou i nā ʻano like ʻole o kēlā me kēia mea.

Hiki i nā lāʻau lapaʻau maʻi diabetes hou e like me GLP-1 agonists a i ʻole SGLT-2 inhibitors ke lilo i mau koho, ʻoiai inā he maʻi puʻuwai kou a pono e lilo i ke kaumaha. E noʻonoʻo kāu kauka i kou olakino holoʻokoʻa i ka wā e ʻōlelo ai i nā koho ʻē aʻe.

Ua ʻoi aku ka maikaʻi o Linagliptin a me Metformin ma mua o Metformin wale nō?

No nā kānaka he nui, hāʻawi kēia hui i ka mana maikaʻi o ke kō koko ma mua o ka metformin wale nō. Hōʻike nā haʻawina i ka hoʻohui ʻana i ka linagliptin i ka metformin hiki ke hoʻohaʻahaʻa i nā pae A1C e 0.5-0.7% hou aʻe i hoʻohālikelike ʻia me ka metformin wale nō.

Hoʻoponopono ka hana hui i ka maʻi diabetes mai nā kihi he nui, kahi e alakaʻi pinepine ai i ka mālama maikaʻi ʻana i ke kō koko. Loaʻa iā ʻoe nā hopena insulin-sensitizing o ka metformin me nā hopena hoʻonui insulin a me ka hoʻohaʻahaʻa ʻana i ka glucagon o ka linagliptin.

Eia naʻe,

E loiloi kāu kauka i nā pōmaikaʻi o ka mālama ʻana i ke kō koko maikaʻi aʻe e kūʻē i nā pilikia e hiki mai ana e pili ana i kou kūlana puʻuwai a me ke olakino holoʻokoʻa.

He aha kaʻu e hana ai inā ua lawe hewa au i ka nui o ka Linagliptin a me Metformin?

Inā ua lawe hewa ʻoe i ka nui ma mua o kāu kauoha, e kelepona koke i kāu kauka a i ʻole ke kikowaena mana ʻawa. ʻO ka lawe ʻana i ka nui hiki ke hoʻonui i kou pilikia o nā hopena ʻaoʻao koʻikoʻi, ʻo ia hoʻi ka lactic acidosis mai ka mea metformin.

E nānā i nā hōʻailona e like me ka ʻeha ʻiʻo maʻamau, nāwaliwali, pilikia i ka hanu ʻana, ka ʻeha o ka ʻōpū, ka nausea, a i ʻole ka manaʻo luhi a i ʻole ke anu. Hiki i kēia mau mea ke hōʻailona o ka lactic acidosis, e koi ana i ka lāʻau lapaʻau koke.

Mai kali e ʻike inā e ulu nā hōʻailona - e ʻimi i ka ʻōlelo aʻo lapaʻau ma hope koke o kekahi overdose. E lawe mai i ka hue lāʻau me ʻoe e kōkua i nā mea mālama ola e hoʻomaopopo pono i ka mea a me ka nui āu i lawe ai.

He aha kaʻu e hana ai inā ua hala au i kahi mahele o Linagliptin a me Metformin?

Inā ua hala ʻoe i kahi mahele, e lawe koke iā ia ke hoʻomanaʻo ʻoe, inā ʻaʻole kokoke ka manawa no kāu mahele i hoʻonohonoho ʻia. Inā kokoke i kou manawa mahele e hiki mai ana, e lele i ka mahele i hala a hoʻomau me kāu papa manawa maʻamau.

Mai lawe i ʻelua mahele i ka manawa hoʻokahi e hoʻoponopono ai i kahi mahele i hala, no ka mea, e hoʻonui kēia i kou pilikia o nā hopena ʻaoʻao. Akā, e hoʻi hou i ke ala me kāu papa manawa maʻamau.

Inā poina pinepine ʻoe i nā mahele, e noʻonoʻo e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila. He mea nui ka hoʻopaʻa ʻana i kēlā me kēia lā i ka mālama ʻana i ke kō koko paʻa.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Linagliptin a me Metformin?

Pono ʻoe e hooki i ka lawe ʻana i kēia lāʻau lapaʻau ma lalo o ka mālama ʻana a kāu kauka. ʻOiai inā e hoʻomaikaʻi nui nā pae kō koko, ʻo ka hooki ʻana i ka lāʻau lapaʻau e hoʻonui hou iā lākou, no ka mea, he maʻi maʻi ka maʻi diabetes type 2.

Hiki i kekahi poʻe ke hoʻemi i ka nui o kā lākou lāʻau lapaʻau inā hana lākou i nā loli nui i ke ola, e like me ka lilo ʻana o ke kaumaha a i ʻole ka hoʻonui ʻana i ka hoʻoikaika kino. Eia naʻe, pono e hana mau ʻia kēia me ka mālie a me ka mālama ʻana o ke kauka.

E loiloi mau kāu kauka i kāu hoʻolālā lapaʻau a hiki ke hoʻoponopono a hoʻololi paha i kāu mau lāʻau lapaʻau e pili ana i kāu kaohi ʻana i ke kō koko, nā hopena ʻaoʻao, a me ke olakino holoʻokoʻa. Mai hana i kēia mau hoʻoholo iā ʻoe iho.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Linagliptin a me Metformin?

Hiki iā ʻoe ke inu i ka waiʻona me ka maʻalahi i ka wā e lawe ana i kēia lāʻau lapaʻau, akā pono ʻoe e mālama nui i kāu pae kō koko. Hiki i ka waiʻona ke hoʻonui i kou pilikia o ke kō koko haʻahaʻa a me ka lactic acidosis, ʻoiai ke hui pū ʻia me ka metformin.

Inā koho ʻoe e inu, e hana pēlā me ka meaʻai a nānā pinepine i kāu kō koko. Hiki i ka hui pū ʻana o ka waiʻona a me nā lāʻau lapaʻau maʻi diabetes ke kumu i ka lohi ʻana o ke kō koko haʻahaʻa, i kekahi manawa i nā hola ma hope o ka inu ʻana.

E kamaʻilio me kāu kauka e pili ana i nā palena palekana o ka inu ʻana i ka waiʻona no kāu kūlana kikoʻī. Hiki iā lākou ke ʻōlelo aku e pale loa i ka waiʻona inā loaʻa iā ʻoe kekahi mau maʻi olakino a i ʻole e lawe i nā lāʻau lapaʻau ʻē aʻe e launa pū me ka waiʻona.