He aha ka Linezolid: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau antibiotic ikaika ka Linezolid e hakakā ana i nā maʻi bacteria koʻikoʻi ke hiki ʻole i nā lāʻau lapaʻau ʻē aʻe ke hana. No kahi papa kūikawā o nā antibiotics i kapa ʻia ʻo oxazolidinones, ʻo ia hoʻi, hana ʻokoʻa ia ma mua o nā lāʻau lapaʻau e hakakā ana i ka maʻi āu e ʻike ai.

He mea waiwai nui kēia lāʻau lapaʻau no ka mea hiki iā ia ke lanakila i kekahi o nā maʻi bacteria paʻakikī loa, me nā mea i hana ʻia e nā bacteria kūpaʻa. Ke loaʻa iā ʻoe ka linezolid ma o ka IV, hele pololei ia i loko o kou kahe koko e hiki koke a maikaʻi i ka maʻi.

No ke aha e hoʻohana ʻia ai ka Linezolid?

Hoʻomaʻamaʻa ka Linezolid i nā maʻi bacteria koʻikoʻi e hiki ke hoʻoweliweli i ke ola inā ʻaʻole i mālama ʻia. Kauoha kāu kauka i kēia lāʻau lapaʻau ke pono lākou i kahi antibiotic ikaika a hilinaʻi e hakakā i nā ʻano bacteria.

He mea maikaʻi loa ka lāʻau lapaʻau i nā bacteria gram-positive, e komo pū ana me kekahi o nā maʻi paʻakikī loa e mālama. He mau paia cell mānoanoa ko kēia mau bacteria e paʻakikī ai i nā antibiotics he nui ke komo.

Eia nā ʻano maʻi nui e kōkua ai ka linezolid i ka mālama ʻana:

• Pneumonia: ʻO ka pneumonia i loaʻa i ka haukapila a me ke kaiāulu, ʻoiai ke hana ʻia e nā bacteria kūpaʻa
• Nā maʻi ʻili a me nā ʻiʻo palupalu: Nā maʻi koʻikoʻi e pili ana i kou ʻili, nā ʻiʻo, a me nā ʻiʻo ma lalo
• Nā maʻi MRSA: Methicillin-resistant Staphylococcus aureus, kahi ʻano maʻi staph e kūʻē ana i nā antibiotics he nui
• Nā maʻi VRE: Vancomycin-resistant enterococci, kekahi ʻano bacteria kūpaʻa
• Nā maʻi kahe koko: Ke komo nā bacteria i kou koko a laha i kou kino a pau

Ko kāu hui mālama ola e koho i ka linezolid i ka wā e pono ai lākou i kahi lāʻau antibiotic e hiki ke hakakā pono i kēia mau maʻi paʻakikī. Hoʻokaʻawale pinepine ʻia ia no nā kūlana i ka wā i hana ʻole ai nā lāʻau antibiotic ʻē aʻe a i ʻole i ka wā i hoʻokumu ʻia ai ka maʻi e nā bacteria kūʻē.

Pehea e Hana ai ka Linezolid?

Hana ka linezolid ma ka hoʻōki ʻana i nā bacteria mai ka hana ʻana i nā protein e pono ai lākou e ola a hoʻonui. E noʻonoʻo iā ia me he mea lā e hoʻopilikia ana i ka hale hana protein o ka bacteria, e alakaʻi ana i ko lākou make.

ʻAʻole like me nā lāʻau antibiotic ʻē aʻe e hoʻouka i nā paia cell o ka bacteria, ua manaʻo ʻia ka linezolid i kahi ʻāpana kikoʻī o ka mīkini kūloko o ka bacteria i kapa ʻia ʻo ribosomes. ʻO kēia ala kūʻokoʻa e hana ai i mea maikaʻi i nā bacteria i hoʻomohala i ke kūʻē ʻana i nā lāʻau antibiotic ʻē aʻe.

Ua manaʻo ʻia kēia lāʻau he lāʻau antibiotic ikaika a mana. ʻO ia ka mea a nā kauka e kapa ai he lapaʻau

I ka wā o kāu lapaʻau ʻana, pono paha ʻoe e kaupalena i nā meaʻai i kiʻekiʻe i ka tyramine. Aia kēia mau mea i nā tīhi kahiko, nā ʻiʻo i hoʻōla ʻia, nā meaʻai i hoʻomoʻa ʻia, a me kekahi mau mea inu ʻona. E hāʻawi kāu kauka a i ʻole ka mea lapaʻau iā ʻoe i kahi papa inoa piha inā pono.

Hoʻolālā ʻia ka manawa o kāu mau lāʻau e kāu hui lapaʻau. E hoʻokaʻawale lākou i nā infusions e mālama i nā pae paʻa o ka lāʻau lapaʻau i loko o kāu ʻōnaehana, e kōkua ana i ka hōʻoia ʻana i ka hopena lapaʻau maikaʻi loa.

Pehea ka lōʻihi e lawe ai au i ka Linezolid?

ʻO ka lōʻihi o kāu lapaʻau linezolid e hilinaʻi ana i ke ʻano a me ke koʻikoʻi o kāu maʻi. ʻO ka hapa nui o nā papa e mau ana ma waena o 10 a 28 mau lā, akā e hoʻoholo kāu kauka i ka lōʻihi pololei e pili ana i kāu kūlana.

E nānā pono kāu hui mālama ola i kāu holomua i ka wā o ka lapaʻau. E loiloi lākou i ka maikaʻi o ka pane ʻana o ka maʻi a hiki ke hoʻololi i ka lōʻihi o ka lapaʻau.

No ka maʻi pneumonia, maʻamau ka lapaʻau ʻana i 10 a 14 mau lā. Pono pinepine nā maʻi ʻili a me nā ʻiʻo palupalu i 10 a 14 mau lā. Pono paha nā maʻi paʻakikī a koʻikoʻi paha i nā manawa lapaʻau lōʻihi.

He mea nui e hoʻopau i ka papa lapaʻau piha, ʻoiai inā hoʻomaka ʻoe e ʻoi aku ka maikaʻi. ʻO ka hooki ʻana i ka wā mua hiki ke ʻae i ka maʻi e hoʻi mai, e paʻakikī paha ke mālama ʻana i ka manawa aʻe.

E hoʻohana kāu kauka i nā hōʻailona like ʻole e hoʻoholo ai i ka manawa e hooki ai i ka lapaʻau. Aia kēia mau mea i ka hoʻomaikaʻi ʻana o kāu mau hōʻailona, ​​e hōʻike ana nā hoʻokolohua koko e hoʻomaʻemaʻe ana ka maʻi, a me nā haʻawina kiʻi inā pono.

He aha nā hopena ʻaoʻao o Linezolid?

E like me nā lāʻau lapaʻau a pau, hiki i ka linezolid ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole ʻike nā kānaka a pau iā lākou. Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao, a e nānā pono kāu hui mālama ola iā ʻoe i ka wā o ka lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike me ka nausea, ke poʻo, a me ka maʻi maʻi. Hiki ke hana pinepine kēia mau mea i nā lā mua o ka lapaʻau a hoʻomaikaʻi pinepine i ka wā e hoʻoponopono ai kou kino i ka lāʻau.

Eia nā hopena ʻaoʻao maʻamau e ʻike ʻia:

• Nā pilikia ʻōpū: ʻO ka nausea, ka luaʻi, ka maʻi palahē, a i ʻole ka ʻōpū
• Nā hōʻailona neurological: ʻO ke poʻo, ka ʻūlū, a i ʻole ka pilikia o ka hiamoe
• Nā hopena ʻili: ʻO ka ʻulaʻula a i ʻole ka ʻūlū ma ka pūnaewele IV
• Nā loli ʻono: ʻO ka ʻono metala a i ʻole nā loli i ke ʻano o ka ʻono o ka meaʻai
• Luhi: ʻOi aku ka luhi ma mua o ka maʻamau

He maʻalahi a he manawa pōkole kēia mau hopena ʻaoʻao. Hiki i kāu hui mālama ola ke kōkua i ka mālama ʻana iā lākou me ka mālama kākoʻo a i ʻole nā hoʻoponopono lāʻau inā pono.

Aia kekahi mau hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e koi ai i ka lāʻau lapaʻau koke. ʻOiai he kakaikahi kēia, he mea nui e ʻike iā lākou.

ʻO nā hopena ʻaoʻao koʻikoʻi e pono ai ka mālama olakino wikiwiki:

• Nā maʻi koko: Maʻalahi ka ʻeha, ke kahe ʻana o ke koko ʻokoʻa, a i ʻole nā hōʻailona o nā helu koko haʻahaʻa
• Nā pilikia nerve: ʻO ka ʻūlū, ka ʻūlū, a i ʻole ka nāwaliwali o nā lima a i ʻole nā wāwae
• Nā loli ʻike: ʻO ka ʻike pōʻeleʻele, nā loli ʻike kala, a i ʻole ka nalowale o ka ʻike
• Maʻi palahē koʻikoʻi: ʻOi loa inā loaʻa ke koko a i ʻole ka mucus
• Nā hopena maʻi: ʻO ka ʻulaʻula nui, ka pilikia o ka hanu, a i ʻole ka pehu

E nānā mau ana kāu hui mālama ola iā ʻoe no kēia mau pilikia hiki. E hana lākou i nā hoʻokolohua koko e nānā i kāu helu koko a nānā i nā hōʻailona o nā pilikia nerve a i ʻole ka ʻike.

ʻO wai ka mea ʻaʻole pono e lawe i ka Linezolid?

Pono kekahi poʻe e pale i ka linezolid a i ʻole pono e nānā kūikawā i ka wā o ka mālama ʻana. E nānā pono kāu kauka i kāu mōʻaukala olakino a me nā lāʻau lapaʻau i kēia manawa ma mua o ke kau ʻana i kēia antibiotic.

ʻAʻole kūpono paha ka poʻe me nā maʻi olakino kikoʻī no ka mālama ʻana i ka linezolid. E noʻonoʻo kāu hui mālama ola i kēia mau mea i ke koho ʻana i kāu antibiotic.

Pono ʻoe e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau maʻi:

• Nā maʻi koko: Mōʻaukala o nā helu koko haʻahaʻa a i ʻole nā pilikia iwi iwi
• Ke koko kiʻekiʻe: ʻOi loa inā ʻaʻole i mālama pono ʻia
• Nā pilikia thyroid: Thyroid hana nui a i ʻole nā maʻi thyroid
• Nā maʻi hopu: Mōʻaukala o nā hopu a i ʻole epilepsy
• Maʻi kīkī a i ʻole ate: Kōkua kēia mau ʻōkana i ka hana ʻana i ka lāʻau

Hiki i kekahi mau lāʻau lapaʻau ke launa pū me ka linezolid. Pono kāu kauka e ʻike e pili ana i nā lāʻau lapaʻau a pau āu e lawe nei, me nā lāʻau lapaʻau i kauoha ʻia, nā lāʻau lapaʻau i kūʻai ʻia, a me nā mea hoʻohui.

ʻO nā lāʻau lapaʻau e launa pū me ka linezolid me nā antidepressants, nā lāʻau lapaʻau koko, a me kekahi mau mea hoʻomaha ʻeha. E nānā kāu hui mālama ola i kāu mau lāʻau lapaʻau a pau e hōʻoia i ka mālama palekana.

Pono nā wahine hāpai a me nā wahine e hānai ana i ka umauma i ka noʻonoʻo kūikawā. ʻOiai hiki ke hoʻohana ʻia ka linezolid i ka wā hāpai inā ʻoi aku ka maikaʻi ma mua o nā pilikia, e noʻonoʻo pono kāu kauka i kēia mau mea.

Nā inoa inoa o Linezolid

Loaʻa ka Linezolid ma lalo o kekahi mau inoa inoa, ʻo Zyvox ka mea i ʻike nui ʻia. Loaʻa i ka mana generic ka mea hana like a hana like me nā mana inoa.

Inā loaʻa iā ʻoe ka inoa inoa a i ʻole ka mana generic e pili ana i ka papa inoa o kāu haukapila a me kāu ʻinikua. Hoʻokō nā mana ʻelua i nā kūlana maikaʻi a me ka palekana.

E hoʻohana kāu hui mālama ola i ka mana i loaʻa a kūpono no kāu mālama ʻana. ʻO ka mea nui, ke loaʻa nei iā ʻoe ka lāʻau lapaʻau kūpono no kāu maʻi, me ka nānā ʻole i ka inoa inoa.

Nā koho ʻē aʻe o Linezolid

He nui nā lāʻau antibiotic ʻē aʻe e hiki ke mālama i nā maʻi like, akā pili ka koho i ka bacteria kikoʻī e hoʻoulu ana i kou maʻi a me kou mau kūlana pilikino. Koho kāu kauka i ke koho maikaʻi loa e pili ana i nā hopena moʻomeheu a me nā hoʻokolohua ʻike.

ʻO nā lāʻau antibiotic ʻē aʻe e hiki i kāu kauka ke noʻonoʻo, ʻo ia ka vancomycin, daptomycin, a i ʻole nā mea hou e like me tedizolid. He ikaika a me nā mea e noʻonoʻo ai kēlā me kēia.

ʻO Vancomycin kekahi lāʻau antibiotic i hoʻohana pinepine ʻia no nā maʻi gram-positive koʻikoʻi. Eia naʻe, ua hoʻomohala kekahi bacteria i ke kūʻē ʻana i ka vancomycin, ʻo ia ke kumu e lilo ai ka linezolid i mea waiwai.

Pili ke koho ma waena o nā lāʻau antibiotic i nā mea e like me ka bacteria kikoʻī i pili, kāu hana kīkī, nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, a me kahi o kāu maʻi. Hoʻohana kāu hui mālama ola i nā hopena laboratory e alakaʻi i kēia hoʻoholo.

Ua ʻoi aku ka maikaʻi o ka Linezolid ma mua o Vancomycin?

He lāʻau antibiotic maikaʻi loa ʻo Linezolid a me vancomycin no ka mālama ʻana i nā maʻi bacteria gram-positive koʻikoʻi, akā he mau pono kūikawā ko kēlā me kēia i nā kūlana like ʻole. Pili ke koho

I kekahi manawa, ʻo ka bacteria e hana ana i kou maʻi e kūʻē paha i kekahi antibiotic akā hiki ke maʻalahi i kekahi. Hāʻawi ka hoʻokolohua laboratory i ke alakaʻi i kēia hoʻoholo nui e hōʻoia e loaʻa iā ʻoe ka lāʻau lapaʻau maikaʻi loa.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Linezolid

He palekana anei ʻo Linezolid no ka poʻe me ka maʻi kīkī?

Hiki ke hoʻohana palekana ʻia ʻo Linezolid i ka poʻe me ka maʻi kīkī, me ka poʻe ma ka dialysis. ʻAʻole like me kekahi mau antibiotics ʻē aʻe, ʻaʻole pono ʻo linezolid i nā hoʻoponopono dose e pili ana i ka hana kīkī.

Eia naʻe, e nānā pono kāu hui mālama ola iā ʻoe inā he pilikia kou kīkī. E nānā lākou i nā hōʻailona o nā hopena ʻaoʻao a hōʻoia i ka hana pono ʻana o ka lāʻau.

Hiki i ka poʻe ma ka dialysis ke loaʻa iā linezolid, akā pono paha ka manawa o nā doses e hoʻonohonoho ʻia me nā kau dialysis. E mālama kāu hui lapaʻau i kēia hoʻonohonoho ʻana e hōʻoia i ka mālama maikaʻi loa.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Linezolid?

No ka mea, hāʻawi ʻia ʻo linezolid e nā poʻe loea mālama ola ma o ka IV, he kakaikahi loa nā overdoses ulia. Hoʻohālikelike a nānā pono kāu hui lapaʻau i kēlā me kēia dose e pale aku i kēia mai ka hana ʻana.

Inā hopohopo ʻoe e pili ana i kāu dose a i ʻole e ʻike i nā hōʻailona maʻamau i ka wā a i ʻole ma hope o kāu infusion, e haʻi koke i kāu kahu hānai a i ʻole kauka. Hiki iā lākou ke loiloi i kou kūlana a hana i ka hana kūpono inā pono.

ʻO nā hōʻailona o ka overdose hiki ke komo i ka nausea koʻikoʻi, ka luaʻi, ka dizziness, a i ʻole nā ​​hōʻailona neurological maʻamau. Ua aʻo ʻia kāu hui mālama ola e ʻike a mālama i kēia mau kūlana inā loaʻa.

He aha kaʻu e hana ai inā hala iaʻu kahi dose o Linezolid?

No ka mea, loaʻa iā ʻoe ka linezolid ma o ka IV i loko o kahi hoʻonohonoho mālama ola, ʻaʻole maʻamau nā doses i hala. Hoʻonohonoho a hāʻawi kāu hui lapaʻau i kāu mau doses e like me ka manawa i hoʻolālā ʻia.

Inā hoʻopaneʻe ʻia kahi lāʻau lapaʻau ma muli o nā kaʻina hana lapaʻau a i ʻole nā kūlana ʻē aʻe, e hoʻoponopono kāu hui mālama ola i ka manawa kūpono. E hōʻoia lākou e loaʻa iā ʻoe ka papa lapaʻau piha e like me ka mea i kauoha ʻia.

Mai hopohopo e pili ana i ka