He aha ka Maralixibat: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau kūikawā ʻo Maralixibat e kōkua ana i ka mālama ʻana i ka ʻūlū nui i hana ʻia e kekahi mau maʻi ate i nā keiki. Hana ia ma ka pale ʻana i nā mea lawe kikoʻī i loko o kou ʻōpū e hoʻopili hou i nā waikawa bile, ʻo ia nā mea hiki ke kūkulu a hoʻoulu i nā hōʻailona ʻoluʻolu ʻole ke hana pono ʻole kou ate.

Hōʻike kēia lāʻau lapaʻau i kahi holomua nui no nā ʻohana e hana ana me nā maʻi ate laha ʻole. ʻOiai ʻaʻole ia he lāʻau lapaʻau, hiki i ka maralixibat ke hāʻawi i ke kōkua nui mai ka ʻūlū nui e hana pinepine i ke ola i kēlā me kēia lā i mea paʻakikī no nā keiki me kēia mau maʻi.

He aha ka Maralixibat?

He lāʻau lapaʻau waha ʻo Maralixibat e pili ana i kahi papa o nā lāʻau i kapa ʻia ʻo ileal bile acid transporter (IBAT) inhibitors. E noʻonoʻo iā ia he mea pale kūikawā e pale ai i kou ʻōpū mai ka hoʻopili hou ʻana i nā waikawa bile, e ʻae ana i ka nui o kēia mau mea e haʻalele maoli i kou kino.

Hele mai ka lāʻau lapaʻau ma ke ʻano he hopena waha i hana kūikawā ʻia no nā keiki. Hoʻolālā ʻia e lawe ʻia e ka waha, hui pū ʻia me ka meaʻai a i ʻole nā mea inu e maʻalahi ai no nā maʻi ʻōpio e lawe mau.

He mea hou kēia lāʻau lapaʻau i ka mākeke, ua hoʻomohala ʻia no nā maʻi pediatric me nā maʻi ate laha ʻole. ʻAʻole hoʻohana nui ʻia no ka mea e kuhikuhi ana i nā kūlana olakino kikoʻī e pili ana i ka helu liʻiliʻi o nā keiki.

No ke aha e hoʻohana ʻia ai ka Maralixibat?

Hoʻohana nui ʻia ʻo Maralixibat e mālama i ka cholestatic pruritus i nā keiki me ka maʻi Alagille. ʻO ka Cholestatic pruritus ka huaʻōlelo lapaʻau no ka ʻūlū nui a mau e hiki mai ana ke kūkulu ʻia nā waikawa bile i loko o kou kino ma muli o nā pilikia o ke ake.

ʻO ka maʻi Alagille he maʻi genetic laha ʻole e pili ana i ke ake, ka puʻuwai, a me nā ʻōkana ʻē aʻe. ʻO nā keiki me kēia maʻi e ʻike pinepine i ka ʻūlū nui e hiki ke hoʻopilikia i ka hiamoe, ke kula, a me nā hana o kēlā me kēia lā. Hiki ke koʻikoʻi ka ʻūlū i ka hopena nui i ko lākou maikaʻi o ke ola.

Hiki nō ke noʻonoʻo ʻia ka lāʻau lapaʻau no nā maʻi ake cholestatic ʻē aʻe i nā keiki, akā ʻaʻole maʻamau kēia hoʻohana. E loiloi pono kāu kauka inā kūpono ka maralixibat no ke kūlana a me nā hōʻailona o kāu keiki.

Pehea e Hana ai ʻo Maralixibat?

Hana ʻo Maralixibat ma ka pale ʻana i kahi protein kikoʻī i loko o kou ʻōpū i kapa ʻia ʻo ka ileal bile acid transporter (IBAT). Kōkua maʻamau kēia protein i kou kino e hoʻopili hou i nā waikawa bile mai kou ʻōpū i loko o kou kahe koko.

Ke ālai ʻia kēia mea lawe, ʻoi aku ka nui o nā waikawa bile e hele i kou ʻōpū a haʻalele i kou kino ma o nā neʻe ʻana o ka ʻōpū. Kōkua kēia i ka hōʻemi ʻana i ka nui o nā waikawa bile e holo ana i loko o kou kahe koko, hiki ke hoʻemi i ka manaʻo ʻūlū.

Ua manaʻo ʻia ka lāʻau lapaʻau he ikaika iki no kāna kumu kikoʻī. ʻAʻole ia he lāʻau lapaʻau maʻamau akā he lāʻau lapaʻau i manaʻo ʻia e pili ana i kahi pilikia kikoʻī loa i ke ʻano o kou kino e hana ai i nā waikawa bile.

Pehea e Lawe ai au i ka Maralixibat?

Pono e lawe ʻia ka Maralixibat e like me ke kau ʻana a kāu kauka, maʻamau hoʻokahi manawa i ka lā i ke kakahiaka. Hele mai ka lāʻau lapaʻau ma ke ʻano he hopena waha e hiki ke hui pū ʻia me ka meaʻai a i ʻole nā mea inu e ʻono ai i nā keiki.

Hiki iā ʻoe ke hāʻawi i kēia lāʻau lapaʻau me ka ʻole a i ʻole ka meaʻai, akā ʻo ka lawe ʻana me ka meaʻai e kōkua i ka hōʻemi ʻana i ka ʻōpū. Nui nā ʻohana i ʻike he mea kōkua ke hui pū i ka hopena me kahi mea liʻiliʻi o ka ʻāpala, yogurt, a i ʻole ka wai e hauʻoli ai kā lākou keiki.

He mea nui e hoʻohana i ka mea ana e hele mai me ka lāʻau lapaʻau e hōʻoia i ka dosage pololei. Mai hoʻohana i nā puna hale, no ka mea, ʻokoʻa ko lākou nui a ʻaʻole paha e hāʻawi i ka dose pololei.

E hoʻāʻo e hāʻawi i ka lāʻau lapaʻau i ka manawa like i kēlā me kēia lā e kōkua i ka hoʻokumu ʻana i kahi hana maʻamau. Kōkua kēia kūlike i ka mālama ʻana i nā pae paʻa o ka lāʻau i loko o ke kino o kāu keiki.

Pehea ka lōʻihi e lawe ai au i ka Maralixibat?

ʻO ka lōʻihi o ka mālama ʻana me ka maralixibat e loli ana ma muli o ke kūlana kikoʻī o kāu keiki a me ka pane ʻana i ka lāʻau lapaʻau. No nā keiki me ka maʻi Alagille, he lapaʻau lōʻihi kēia e hiki ke hoʻomau no nā makahiki.

E nānā mau kāu kauka i ka holomua o kāu keiki a hoʻoponopono i ka hoʻolālā lapaʻau e like me ka mea e pono ai. Hiki i kekahi mau keiki ke ʻike i ka hoʻomaikaʻi ʻana i ka ʻūlū i loko o kekahi mau pule, ʻoiai e lōʻihi ana ka poʻe ʻē aʻe e ʻike i nā pōmaikaʻi.

ʻO ka hoʻoholo e hoʻomau a hoʻōki paha i ka lapaʻau e hana mau ʻia ma ke kūkākūkā ʻana me kāu mea mālama ola. E noʻonoʻo lākou i nā mea e like me ka hoʻomaikaʻi ʻana i nā hōʻailona, ​​nā hopena ʻaoʻao, a me ke kūlana olakino holoʻokoʻa o kāu keiki.

He aha nā hopena ʻaoʻao o Maralixibat?

E like me nā lāʻau lapaʻau a pau, hiki i ka maralixibat ke hoʻoulu i nā hopena ʻaoʻao, ʻoiai ʻaʻole ʻike nā kānaka a pau iā lākou. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e mākaukau a ʻike i ka manawa e hoʻokaʻaʻike aku ai i kāu mea mālama ola.

ʻO nā hopena ʻaoʻao maʻamau e pili ana i nā loli ʻōnaehana digestive, he mea kūpono ia i ka hana ʻana o ka lāʻau lapaʻau i loko o kou ʻōpū.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia:

• Pāpaʻa a i ʻole nā ​​pahu palupalu
• ʻEha ʻōpū a i ʻole ka ʻūlū
• Nausea a i ʻole ka luaʻi
• Ka nalowale o ka ʻai
• Luhi a i ʻole ka luhi

Hoʻomaikaʻi pinepine kēia mau hopena ʻaoʻao digestive i ka wā e hoʻoponopono ai ke kino o kāu keiki i ka lāʻau lapaʻau. Eia naʻe, hiki i ka maʻi maʻi mau ke hopohopo a pono e kūkākūkā ʻia me kāu kauka.

ʻO nā hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e koi ana i ka lāʻau lapaʻau koke, ʻo ia:

• Ka luaʻi nui a i ʻole ka luaʻi mau
• Nā hōʻailona o ka maloʻo (waha maloʻo, ka mimi liʻiliʻi, ka wili)
• ʻEha nui o ka ʻōpū
• Ke koko i loko o ka waihona
• Nā loli nui i ke ʻano a i ʻole ka manaʻo

Inā ʻike ʻoe i kekahi o kēia mau hopena ʻaoʻao koʻikoʻi, e hoʻokaʻaʻike koke i kāu mea mālama ola. Hiki iā lākou ke kōkua i ka hoʻoholo ʻana inā pili nā hōʻailona i ka lāʻau a hoʻoponopono i ka lāʻau inā pono.

ʻO wai ka mea pono ʻole e lawe iā Maralixibat?

ʻAʻole kūpono ʻo Maralixibat no nā mea a pau, a aia kekahi mau kūlana kahi e pale ʻia ai kēia lāʻau a i ʻole e hoʻohana ʻia me ka akahele hou. E nānā pono kāu kauka i ka mōʻaukala olakino o kāu keiki ma mua o ke kau ʻana i kēia lāʻau.

ʻO nā keiki i ʻole e lawe iā maralixibat me:

• ʻIke ʻia ka maʻi allergy iā maralixibat a i ʻole kekahi o kāna mau meaʻai
• Ka pale ʻana o ka biliary piha (ka pale piha ʻana o nā ducts bile)
• ʻO ka maʻi ate nui
• ʻO ka maʻi ʻāʻī ʻāʻī
• Nā pilikia kīkī nui

Pono ka akahele kūikawā no nā keiki me kekahi mau maʻi e hiki ke hoʻonui i ka pilikia o nā pilikia mai nā hopena o ka lāʻau i ka ʻōnaehana digestive.

E noʻonoʻo pū kāu kauka i nā lāʻau ʻē aʻe a kāu keiki e lawe nei, no ka mea, hiki i kekahi mau lāʻau lapaʻau ke launa pū me maralixibat. E hāʻawi mau i kahi papa inoa piha o nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā huaora a kāu keiki e lawe nei.

Maralixibat Brand Name

Loaʻa ʻo Maralixibat ma lalo o ka inoa brand Livmarli ma ʻAmelika Hui Pū ʻIa. ʻO kēia wale nō ka inoa brand i loaʻa i kēia manawa no kēia lāʻau.

Ua hoʻokumu kūikawā ʻia ʻo Livmarli ma ke ʻano he hopena waha no nā maʻi pediatric. ʻAʻohe mana generic o maralixibat i loaʻa i kēia manawa, no ka mea, he lāʻau hou ia.

Hele mai ka lāʻau lapaʻau inoa inoa me nā ʻōlelo kikoʻī a me nā mea ana i hoʻolālā ʻia no ka ana pololei ʻana i nā keiki. E hoʻohana mau i nā huahana e hele mai me kāu kauoha e hōʻoia i ka ana kūpono.

Nā koho ʻē aʻe o Maralixibat

He palena nā koho lapaʻau no ka pruritus cholestatic i nā keiki, ʻo ia ke kumu e hōʻike ai ʻo maralixibat i kahi holomua nui. Eia naʻe, aia nā ala ʻē aʻe e noʻonoʻo ai kāu kauka.

ʻO nā lapaʻau kuʻuna no ka ʻū ʻana i ka maʻi ate e komo pū ana:

• Ursodeoxycholic acid (he waikawa bile e hiki ke kōkua i ka hana ate)
• Cholestyramine (he mea hoʻopaʻa waikawa bile)
• Rifampin (he antibiotic me nā waiwai anti-itch)
• Antihistamines no ka hōʻoluʻolu symptomatic
• Nā lapaʻau topical e like me nā lotions hoʻoluʻu

Hana kēia mau koho ʻē aʻe ma o nā ʻano hana like ʻole a hiki ke hoʻohana ʻia wale nō a i hui pū ʻia me maralixibat. E hoʻoholo kāu kauka i ke ala lapaʻau maikaʻi loa e pili ana i ke kūlana a me nā hōʻailona o kāu keiki.

Hiki i nā ala hana ʻole i ka lāʻau lapaʻau e like me ka mālama ʻana i ka mālama ʻili maikaʻi, ka hoʻohana ʻana i nā kopa mālie, a me ka mālama ʻana i ke kaiapuni i ke anuanu a me ka haʻahaʻa ke kōkua i ka mālama ʻana i nā hōʻailona ʻū.

ʻOi aku ka maikaʻi o Maralixibat ma mua o Cholestyramine?

Hana ʻokoʻa ʻo Maralixibat a me cholestyramine e hoʻoponopono i nā pilikia e pili ana i ka waikawa bile, a he mau pono a me nā palena ko lākou. ʻO ke koho ma waena o lākou e pili ana i ke kūlana kikoʻī o kāu keiki a me ka pane ʻana i ka lāʻau lapaʻau.

Hāʻawi ʻo Maralixibat i kekahi mau mea maikaʻi ma luna o cholestyramine. He maʻalahi ke lawe no ka mea hele mai ia ma ke ʻano he wai wai e hiki ke hui pū ʻia me ka meaʻai, ʻoiai ʻo cholestyramine he pauka e paʻakikī ke hui a he ʻono ʻoluʻolu ʻole.

Hana ʻo Cholestyramine ma ka hoʻopaʻa ʻana i nā waikawa bile i loko o nā ʻōpū, ʻoiai ʻo maralixibat e ālai i ko lākou reabsorption. ʻO kēia ʻokoʻa i ka hana ʻana, ʻo ia paha ka hana maikaʻi no nā keiki like ʻole a i ʻole hiki ke hoʻohana pū ʻia i kekahi mau hihia.

E noʻonoʻo kāu kauka i nā mea e like me ka makahiki o kāu keiki, ka hiki ke lawe i nā lāʻau lapaʻau, ke koʻikoʻi o nā hōʻailona, a me nā pane lapaʻau ma mua i ke koho ʻana ma waena o kēia mau koho. Hiki i kekahi mau keiki ke pōmaikaʻi mai ka hoʻāʻo ʻana i nā ala ʻelua e ʻike ai i ka mea e hana maikaʻi ai no lākou.

Nā Nīnau i Nīnau pinepine ʻia e pili ana iā Maralixibat

He palekana anei ʻo Maralixibat no nā keiki me nā pilikia o ka naʻau?

Nui nā keiki me ka maʻi Alagille i loaʻa pū kekahi i nā pilikia o ka naʻau, no laila he mea nui kēia e noʻonoʻo ai. Hiki ke hoʻohana palekana ʻia ʻo Maralixibat i nā keiki me nā maʻi o ka naʻau, akā pono kāu kauka e nānā pono i kāu keiki.

ʻAʻole pili pololei ka lāʻau lapaʻau i ka hana o ka naʻau, akā hiki i nā hopena ʻaoʻao digestive e like me ka maʻi maʻi ke alakaʻi i ka dehydration, kahi e hoʻonui ai i ke koʻikoʻi i ka naʻau. E hana pū kāu hui mālama ola e hōʻoia i ka noʻonoʻo ʻia ʻana o nā mea a pau o ke olakino o kāu keiki.

He aha kaʻu e hana ai inā hāʻawi hewa au i ka nui o Maralixibat?

Inā hāʻawi hewa ʻoe i kāu keiki i ka nui o ka maralixibat, e kelepona koke i kāu kauka a i ʻole ke kikowaena mana ʻawa. ʻOiai ua kaupalena ʻia ka ʻike overdose ma muli o ka hou o ka lāʻau lapaʻau, hiki i nā mea nui ke kumu i nā hōʻailona digestive koʻikoʻi.

E nānā i nā hōʻailona o ka maʻi maʻi koʻikoʻi, ka luaʻi ʻana, a i ʻole ka dehydration, a e ʻimi i ka lāʻau lapaʻau inā kū mai kēia mau mea. E mālama i ka hue lāʻau lapaʻau me ʻoe i ka wā e ʻimi ai i ke kōkua i hiki i nā mea mālama ola ke ʻike pololei i ka mea a me ka nui i hāʻawi ʻia.

He aha kaʻu e hana ai inā hala wau i kahi mahele o Maralixibat?

Inā hala ʻoe i kahi mahele o ka maralixibat, e hāʻawi iā ia i ka wā e hoʻomanaʻo ai ʻoe, ke ʻole kokoke ka manawa no ka mahele aʻe. I kēlā hihia, e lele i ka mahele i hala a e hoʻomau me ka papa manawa maʻamau.

Mai hāʻawi i ʻelua mahele i ka manawa hoʻokahi e hoʻoponopono ai i kahi mahele i hala, no ka mea, hiki i kēia ke hoʻonui i ka pilikia o nā hopena ʻaoʻao. Inā poina pinepine ʻoe i nā mahele, e noʻonoʻo e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho lāʻau lapaʻau e kōkua i ka mālama ʻana i ke kūlike.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Maralixibat?

Mai hooki i ka hāʻawi ʻana iā maralixibat me ke kūkākūkā ʻole ʻana me kāu kauka. Pono e hoʻokumu ʻia ka hoʻoholo e hooki i ka lapaʻau ʻana ma muli o ka pane ʻana o kāu keiki i ka lāʻau lapaʻau, nā hopena ʻaoʻao, a me ke kūlana olakino holoʻokoʻa.

Hiki i kāu kauka ke ʻōlelo aku e hooki inā loaʻa i kāu keiki nā hopena ʻaoʻao nui e ʻoi aku ana i nā pōmaikaʻi, a i ʻole inā e hoʻomaikaʻi ana ko lākou kūlana i kahi e pono ʻole ai ka lāʻau lapaʻau. E alakaʻi lākou iā ʻoe ma o nā hoʻemi ʻana i ka mahele lāʻau a i ʻole ka nānā ʻana i ka wā o ke kaʻina hana hooki.

Hiki ke lawe ʻia ʻo Maralixibat me nā lāʻau lapaʻau ʻē aʻe?

Hiki i ka Maralixibat ke launa pū me nā lāʻau lapaʻau ʻē aʻe, ʻo ia hoʻi nā mea i komo i loko o nā ʻōpū. E hōʻike mau i kāu kauka e pili ana i nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā huaora a kāu keiki e lawe ai ma mua o ka hoʻomaka ʻana iā maralixibat.

Pono paha e lawe ʻia kekahi mau lāʻau lapaʻau i nā manawa like ʻole o ka lā e pale ai i nā pilina, aʻo nā mea ʻē aʻe e koi ai i nā hoʻoponopono ʻana i ka mahele lāʻau. E hana kāu mea mālama ola i kahi papa hana lāʻau lapaʻau piha e hoʻonui i nā pōmaikaʻi me ka hōʻemi ʻana i nā pilikia.