He aha ka Mechlorethamine: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau chemotherapy ʻo Mechlorethamine i hoʻohana ʻia e mālama i kekahi mau ʻano maʻi maʻi, me nā lymphomas a me ka leukemia. Hana kēia lāʻau lapaʻau ikaika ma ka hoʻopilikia ʻana i ka ulu ʻana a me ka mahele ʻana o nā cell maʻi maʻi, e kōkua ana e hoʻolohi a i ʻole e hoʻōki i ka laha ʻana o nā cell malignant i loko o kou kino. ʻOiai he lāʻau lapaʻau ikaika me nā hopena nui, ʻo ka hoʻomaopopo ʻana i ke ʻano o kāna hana a me ka mea e manaʻo ai hiki ke kōkua iā ʻoe e mākaukau no kāu huakaʻi lapaʻau.

He aha ka Mechlorethamine?

No ka papa o nā lāʻau chemotherapy i kapa ʻia ʻo alkylating agents ʻo Mechlorethamine. Hana kēia mau lāʻau lapaʻau ma ka hōʻino ʻana i ka DNA i loko o nā cell maʻi maʻi, e pale ana iā lākou mai ka hoʻonui ʻana a me ka laha ʻana i loko o kou kino. ʻO ia kekahi o nā lāʻau chemotherapy kahiko, i hoʻomohala mua ʻia i nā makahiki 1940, akā he koho lapaʻau koʻikoʻi ia no nā ʻano maʻi koko.

Hāʻawi ʻia ka lāʻau lapaʻau ma o ka laina intravenous (IV), ʻo ia hoʻi, hāʻawi pololei ʻia i loko o kou kahe koko ma o ka vein. Hoʻomaopopo kēia ʻano hana i ka lāʻau lapaʻau i nā cell maʻi maʻi i loko o kou kino me ka wikiwiki a me ka maikaʻi. E nānā pono kāu hui mālama ola iā ʻoe i ka wā a ma hope o kēlā me kēia lapaʻau e hōʻoia i kou palekana a me kou hōʻoluʻolu.

No ke aha i hoʻohana ʻia ai ʻo Mechlorethamine?

Hoʻohana nui ʻia ʻo Mechlorethamine e mālama i ka lymphoma o Hodgkin a me kekahi mau ʻano o ka lymphoma non-Hodgkin. He ʻāpana pinepine ia o kahi regimen chemotherapy hui pū, ʻo ia hoʻi e loaʻa iā ʻoe me nā lāʻau lapaʻau e hakakā ana i ka maʻi maʻi e hoʻonui i kona pono. Hiki i kāu oncologist ke kuhikuhi iā ia no nā maʻi koko ʻē aʻe a i ʻole nā ​​tumors paʻa i nā kūlana kikoʻī.

He mea pono loa ka lāʻau lapaʻau i ka wā i laha ai ka maʻi 'aʻai i nā wahi he nui o kou kino a i ʻole i ka wā i kūpono ʻole ai nā lāʻau lapaʻau ʻē aʻe. I kekahi manawa, hoʻohana nā kauka i ka mechlorethamine ma ke ʻano he ʻāpana o ka hoʻoponopono ʻana ma mua o ka hoʻololi ʻana i ka iwi iwi a i ʻole ke keʻena stem cell. I kēia mau hihia, kōkua ia i ka hoʻomākaukau ʻana i kou kino ma ka hoʻemi ʻana i ka helu o nā pūnaewele maʻi 'aʻai a me ka hana ʻana i kahi no nā pūnaewele olakino hou e ulu.

Pehea e hana ai ʻo Mechlorethamine?

Ua manaʻo ʻia ʻo Mechlorethamine he lāʻau chemotherapy ikaika e kālele ana i nā pūnaewele e mahele wikiwiki ana. Hana ia ma ka hana ʻana i nā paʻa kemika me ka DNA i loko o nā pūnaewele maʻi 'aʻai a me kekahi mau pūnaewele olakino, e pale ana iā lākou mai ka kope pono ʻana iā lākou iho. Ke hiki ʻole i nā pūnaewele ke mahele maʻamau, make lākou, e kōkua ana i ka hoʻemi ʻana i ka helu o nā pūnaewele maʻi 'aʻai i kou kino.

No ka mea, ʻoi aku ka pinepine o ka mahele ʻana o nā pūnaewele maʻi 'aʻai ma mua o ka hapa nui o nā pūnaewele olakino, ʻoi aku ka maʻalahi o lākou i nā hopena o kēia lāʻau lapaʻau. Eia naʻe, hiki i kekahi mau pūnaewele olakino e mahele wikiwiki ana, e like me nā mea i loko o kou iwi iwi, nā lauoho lauoho, a me ka ʻōpū digestive, ke hoʻopilikia ʻia. ʻO ia ke kumu e ʻike ai ʻoe i kekahi mau hopena ʻaoʻao i ka wā o ka mālama ʻana, e kōkua kāu hui mālama ola iā ʻoe e mālama.

Pehea wau e lawe ai iā Mechlorethamine?

E loaʻa iā ʻoe ka mechlorethamine ma ke ʻano he infusion intravenous i loko o kahi haukapila a i ʻole ke kikowaena mālama maʻi 'aʻai. Hāʻawi ʻia ka lāʻau lapaʻau me ka lohi ma o ka laina IV, maʻamau ma luna o 10 a 15 mau minuke, ma lalo o ka nānā ʻana i ka lāʻau lapaʻau. E nānā pono kāu hui mālama ola iā ʻoe i ka wā o ke kaʻina hana holoʻokoʻa e hōʻoia i kou palekana a me kou hōʻoluʻolu.

Ma mua o kēlā me kēia lapaʻau, pono ʻoe e hana i nā hoʻokolohua koko e nānā i kāu helu pūnaewele koko a me ka hana o nā ʻōkana. He mea nui e hōʻea me ka wai maikaʻi, no laila e inu nui i ka wai i ka lā ma mua a me ke kakahiaka o kāu lapaʻau ke ʻole e ʻōlelo ʻia e kāu kauka. Hiki nō hoʻi iā ʻoe ke loaʻa nā lāʻau lapaʻau ma mua e kōkua ai i ka pale ʻana i ka nausea a me nā hopena maʻi.

Ma muli o ka manawa o kāu mau lapaʻau i kāu hoʻolālā lapaʻau kikoʻī, akā, ua hoʻokaʻawale ʻia nā pōʻaiapuni ma waena o 3 a 4 pule. Hāʻawi kēia i kou kino i ka manawa e ola ai ma waena o nā meaʻai. E hoʻoholo kāu oncologist i ka papa manawa pololei ma muli o kou kūlana, pehea ka maikaʻi o kou pane ʻana i ka lapaʻau, a pehea e mālama ai kou kino i ka lāʻau.

Pehea ka lōʻihi e lawe ai au i ka Mechlorethamine?

ʻO ka lōʻihi o kāu lapaʻau mechlorethamine e hilinaʻi ana i nā mea he nui, me ke ʻano a me ke kahua o kāu maʻi ʻaʻai, pehea ka maikaʻi o kou pane ʻana i ka lapaʻau, a me kou olakino holoʻokoʻa. Loaʻa ka hapa nui o nā kānaka i nā mahina he nui ma ke ʻano he ʻāpana o kahi hoʻolālā lapaʻau i hoʻolālā ʻia, e pili ana i 4 a 6 mau pōʻaiapuni o ka chemotherapy.

E nānā mau kāu oncologist i kou holomua ma o nā hoʻokolohua koko, nā kiʻi kiʻi, a me nā hoʻokolohua kino. Inā pane maikaʻi ka maʻi ʻaʻai a ke ʻae nei ʻoe i ka lāʻau me ka ʻole o nā pilikia koʻikoʻi, e hoʻopau paha ʻoe i ka papa i hoʻolālā ʻia. Eia naʻe, inā e ulu nā hopena ʻaoʻao nui a i ʻole ʻaʻole e pane ka maʻi ʻaʻai e like me ka mea i manaʻo ʻia, hiki i kāu kauka ke hoʻololi i kāu hoʻolālā lapaʻau.

Mai hooki i ka lawe ʻana i ka mechlorethamine a i ʻole e nalo i nā lapaʻau i hoʻonohonoho ʻia me ka ʻole e kūkākūkā mua me kāu hui mālama ola. ʻOiai inā ʻaʻole ʻoe maikaʻi, aia paha nā ala e mālama ai i kāu mau hōʻailona i ka wā e hoʻomau nei i ka lapaʻau. Hiki i kāu oncologist ke hoʻololi i kāu mahele a i ʻole ka papa manawa inā pono e kōkua iā ʻoe e hoʻopau i kāu papa lapaʻau piha me ka palekana.

He aha nā hopena ʻaoʻao o Mechlorethamine?

ʻO ka hoʻomaopopo ʻana i nā hopena ʻaoʻao o mechlorethamine hiki ke kōkua iā ʻoe e hoʻomākaukau a ʻike i ka manawa e hoʻopili ai i kāu hui mālama ola. ʻOiai ʻaʻole nā ​​kānaka a pau e ʻike i nā hopena ʻaoʻao a pau, he mea nui e ʻike i ka mea e hiki ke hana i hiki iā ʻoe ke loaʻa ke kōkua koke ke pono.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia ka nausea, ka luaʻi ʻana, a me ka luhi. Hiki ke hana pinepine kēia mau mea i loko o nā hola a i ʻole nā lā ma hope o ka mālama ʻana a hoʻomaikaʻi pinepine ma mua o kāu pōʻai aʻe. E hāʻawi kāu hui mālama ola i nā lāʻau a me nā hoʻolālā e kōkua i ka mālama ʻana i kēia mau hōʻailona.

Eia nā hopena ʻaoʻao i hōʻike pinepine ʻia e ʻike ʻia e nā maʻi he nui:

• Nausea a me ka luaʻi ʻana, hiki ke mālama ʻia me nā lāʻau anti-nausea
• Luhi a me ka nāwaliwali e mau ana no kekahi mau lā ma hope o ka mālama ʻana
• Ka nalowale o ka ʻai a me nā loli i ka ʻono
• Ka nalowale o ka lauoho, he mea manawa wale nō a hoʻomaka i 2-3 mau pule ma hope o ka hoʻomaka ʻana o ka mālama ʻana
• Nā ʻeha waha a i ʻole ka huhū ʻana o ka ʻāʻī
• Diarrhea a i ʻole constipation
• Hoʻonui ʻia ka pilikia o ka maʻi ma muli o ka helu haʻahaʻa o nā keʻena koko keʻokeʻo

Hiki ke mālama ʻia kēia mau hopena ʻaoʻao me ke kākoʻo kūpono, a e hana kāu hui mālama ola me ʻoe e hōʻemi i ko lākou hopena i kou ola i kēlā me kēia lā.

Pono kekahi mau hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi i ka nānā ʻana i ka lāʻau lapaʻau koke. ʻOiai ʻaʻole hiki kēia mau mea i ka hapa nui o nā kānaka, he mea nui e ʻike i nā hōʻailona ʻōlelo aʻo i hiki iā ʻoe ke loaʻa ke kōkua wikiwiki inā loaʻa lākou.

E hoʻokaʻaʻike koke i kāu hui mālama ola inā ʻike ʻoe i kekahi o kēia mau hopena ʻaoʻao koʻikoʻi:

• Fiva ma luna o 100.4°F (38°C) a i ʻole nā hōʻailona o ka maʻi
• Ke kahe ʻana o ke koko a i ʻole ka ʻeha ʻana
• Nausea koʻikoʻi a mau loa a me ka luaʻi ʻana
• Paʻakikī ka hanu ʻana a i ʻole ka ʻeha o ka umauma
• Nā hopena ʻili koʻikoʻi a i ʻole nā ʻōpala
• Melemele o ka ʻili a i ʻole nā maka
• ʻEha nui o ka ʻōpū

Loaʻa ka ʻike o kāu hui mālama ola i ka mālama ʻana i kēia mau hopena ʻaoʻao a e hāʻawi iā ʻoe i nā ʻōlelo kikoʻī i ka wā e kāhea ai i ke kōkua a me nā hōʻailona e nānā ai.

Aia kekahi mau hopena lōʻihi loa akā hiki ke koʻikoʻi e nānā ʻia e kāu oncologist i ka wā a ma hope o ka mālama ʻana. Aia kēia mau mea i nā maʻi ʻaʻai lua, hiki ke ulu i nā makahiki ma hope mai, a me nā hopena i ka puʻuwai, nā māmā, a i ʻole ke akepaʻa. E kōkua nā koho ukali maʻamau i ka ʻike ʻana i nā pilikia i ka wā mua ke hiki ke mālama ʻia.

ʻO wai ka mea pono ʻole e lawe iā Mechlorethamine?

ʻAʻole pono kekahi poʻe e loaʻa iā mechlorethamine a i ʻole e pono paha i nā hana kūikawā i ka wā o ka mālama ʻana. E nānā pono kāu oncologist i kāu mōʻaukala olakino a me ke kūlana olakino i kēia manawa ma mua o ke kau ʻana i kēia lāʻau lapaʻau e hōʻoia i ka palekana iā ʻoe.

ʻAʻole pono ʻoe e loaʻa iā mechlorethamine inā he maʻi ʻoe i ka lāʻau lapaʻau a i ʻole nā lāʻau chemotherapy like. Pono paha nā poʻe me ka hoʻopaʻa ʻana i ka iwi iwi koʻikoʻi a i ʻole nā maʻi maʻi e pale i kēia lāʻau lapaʻau a hiki i ka wā e hoʻomaikaʻi ai ko lākou kūlana. Eia kekahi, inā he maʻi kīkī a i ʻole ke akepaʻa koʻikoʻi, hiki i kāu kauka ke koho i nā lāʻau lapaʻau ʻē aʻe a i ʻole e hoʻoponopono pono i kāu dosage.

ʻAʻole pono nā wahine hāpai e loaʻa iā mechlorethamine no ka mea hiki iā ia ke hōʻeha i ka pēpē e ulu ana. Inā ʻoe i ka makahiki hānau keiki, e kūkākūkā kāu hui mālama ola i nā ʻano hana hoʻomalu hānau ma mua o ka hoʻomaka ʻana i ka mālama ʻana. Pono nō hoʻi nā makuahine e hānai ana e hooki i ka hānai ʻana i ka wā o ka mālama ʻana, no ka mea, hiki i ka lāʻau lapaʻau ke hele i loko o ka waiū umauma.

Pono paha nā poʻe me kekahi mau maʻi puʻuwai, maʻi māmā koʻikoʻi, a i ʻole nā ʻōnaehana pale i hoʻopilikia ʻia i ka nānā ʻana a i ʻole nā hoʻoponopono ʻana i ka dosage. E kaupaona kāu oncologist i nā pōmaikaʻi o ka mālama ʻana i nā pilikia hiki ke loaʻa i kēia mau kūlana, e kūkākūkā pinepine ana me nā loea ʻē aʻe e hōʻoia i kou palekana.

Nā inoa inoa inoa Mechlorethamine

Loaʻa ʻo Mechlorethamine ma lalo o ka inoa inoa ʻo Mustargen ma nā ʻāina he nui. ʻO kēia ka inoa inoa i ʻike nui ʻia no ka lāʻau lapaʻau, ʻoiai hiki ke loaʻa nā mana generic ma muli o kou wahi a me ka ʻōnaehana mālama ola.

Hiki i kekahi mau kikowaena lapaʻau ke kuhikuhi iā ia ma kona inoa kemika, nitrogen mustard, a i ʻole e hoʻokomo iā ia ma ke ʻano he ʻāpana o nā hoʻolālā chemotherapy hui pū me nā inoa kikoʻī e like me MOPP (mechlorethamine, vincristine, procarbazine, a me prednisone). E hōʻoia mau kāu hui mālama ola i nā lāʻau lapaʻau āu e loaʻa nei a me ko lākou mau inoa kikoʻī e pale aku i ka huikau.

Nā Koho ʻē aʻe no Mechlorethamine

Hiki ke hoʻohana ʻia kekahi mau lāʻau chemotherapy ʻē aʻe ma kahi o mechlorethamine, ma muli o kāu ʻano maʻi maʻi a me nā kūlana pilikino. Aia kēia mau koho ʻē aʻe i nā mea hana alkylating ʻē aʻe e like me cyclophosphamide, chlorambucil, a i ʻole bendamustine, e hana like ana akā he ʻokoʻa paha nā hopena ʻaoʻao.

No ka lymphoma o Hodgkin, makemake ʻia nā hoʻolālā hou e like me ABVD (adriamycin, bleomycin, vinblastine, a me dacarbazine) a i ʻole BEACOPP i hoʻonui ʻia i kekahi mau kūlana. E noʻonoʻo kāu oncologist i nā mea e like me kou makahiki, ke olakino holoʻokoʻa, ke kahua o ka maʻi maʻi, a me nā lāʻau lapaʻau mua i ke koho ʻana i ke koho kūpono loa no ʻoe.

I kekahi mau hihia, hiki ke noʻonoʻo ʻia nā lāʻau lapaʻau i manaʻo ʻia, immunotherapy, a i ʻole radiation therapy ma ke ʻano he koho ʻē aʻe a i ʻole nā mea hoʻohui i ka chemotherapy. Hoʻokumu nui ʻia kēia mau hoʻoholo a pili i ka noiʻi hou loa a me nā alakaʻi lapaʻau no kou kūlana kikoʻī.

ʻOi aku ka maikaʻi o Mechlorethamine ma mua o nā lāʻau chemotherapy ʻē aʻe?

ʻAʻole pono ʻo Mechlorethamine i

No nā lymphoma kekahi, he moʻolelo lōʻihi ko mechlorethamine o ka holomua, ʻoiai ke hoʻohana ʻia me nā lāʻau ʻē aʻe. Eia naʻe, makemake ʻia nā ʻano chemotherapy hou no nā maʻi he nui ma muli o ka maikaʻi ʻoi aku a i ʻole nā hopena ʻaoʻao hiki ke mālama ʻia. E koho kāu oncologist i ke ʻano lapaʻau e hāʻawi iā ʻoe i ka manawa maikaʻi loa o ka holomua me ka hōʻemi ʻana i nā pilikia.

ʻO ka

ʻO nā hōʻailona o ka loaʻa ʻana o ka lāʻau lapaʻau nui loa, e komo paha i ka nausea nui, ka luaʻi, a i ʻole ka luhi ʻole. E nānā kāu hui lapaʻau i kāu helu koko i nā manawa pinepine a hāʻawi paha i nā lāʻau lapaʻau hou e kōkua i ka pale ʻana i kou mau ʻōkana a mālama i nā hopena ʻaoʻao e ulu ana.

He aha kaʻu e hana ai inā ua hala wau i kahi mahele o Mechlorethamine?

Inā ua hala ʻoe i kahi lapaʻau mechlorethamine i hoʻonohonoho ʻia, e kelepona i ke keʻena o kāu oncologist i ka wā hiki loa e hoʻonohonoho hou. Mai hoʻāʻo e

Hiki i ka nui o nā kānaka ke hoʻomau i ka hana ʻoiai e loaʻa ana ka mechlorethamine, akā pono paha ʻoe e hana i kekahi mau hoʻoponopono i kāu papa hana. Hāʻawi ʻia ka lāʻau lapaʻau i kēlā me kēia 3-4 pule, a ʻo nā hopena ʻaoʻao e like me ka luhi a me ka nausea e ʻoi aku ka ikaika i nā lā mua ma hope o ka mālama ʻana.

E noʻonoʻo e hoʻolālā i kāu papa hana lapaʻau a puni kāu mau hana hana ke hiki, a e kamaʻilio me kāu mea hana e pili ana i nā hoʻonohonoho maʻalahi inā pono. Manaʻo kekahi poʻe he mea kōkua ke hoʻonohonoho i nā lāʻau lapaʻau i nā Pōʻalima i hiki iā lākou ke hoʻomaha i ka hopena pule, ʻoiai makemake kekahi poʻe i ka manawa ʻē aʻe e pili ana i kā lākou pane pilikino i ka lāʻau lapaʻau.