He aha ka Necitumumab: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i manaʻo ʻia ʻo Necitumumab e kōkua ana i ka mālamaʻana i kahi maʻi maʻi maʻi māmā i kapa ʻia ʻo squamous non-small cell lung cancer. Hana kēia lāʻau lapaʻau ma ka pale ʻana i nā protein e kōkua ana i nā pūnaewele maʻi e ulu a laha i loko o kou kino.

Inā ua ʻōlelo kāu kauka iā necitumumab ma ke ʻano he ʻāpana o kāu hoʻolālā lapaʻau, he mau nīnau paha kāu e pili ana i ke ʻano o kāna hana a me ka mea e manaʻo ai. E hele kākou i nā mea a pau e pono ai ʻoe e ʻike e pili ana i kēia lāʻau lapaʻau ma ke ʻano e hiki ai ke mālama a maopopo.

He aha ka Necitumumab?

He antibody i hana ʻia ma ka hale hana ʻo Necitumumab e manaʻo ana i nā pūnaewele maʻi maʻi. E noʻonoʻo iā ia he missile alakaʻi e ʻimi a hoʻopili i nā pūnaewele maʻi maʻi me ka waiho ʻana i ka hapa nui o kāu mau pūnaewele olakino.

No ka papa o nā lāʻau lapaʻau i kapa ʻia he monoclonal antibodies kēia lāʻau lapaʻau. He mau protein i hoʻolālā kūikawā ʻia kēia mau mea e hiki ke ʻike a pili i nā pahuhopu kikoʻī ma nā pūnaewele maʻi maʻi. Ke hoʻopili ʻia, kōkua ʻo necitumumab i ka hoʻōki ʻana i ka maʻi mai ka ulu ʻana a hiki ke kōkua i kāu ʻōnaehana pale e hakakā i ka maʻi me ka ʻoi aku ka maikaʻi.

E loaʻa iā ʻoe ka necitumumab ma o ka IV infusion ma kahi kikowaena lapaʻau maʻi a i ʻole ka haukapila. He wai maopopo ka lāʻau lapaʻau e hui pū ʻia me ka hopena saline ma mua o ka hāʻawi ʻia ʻana iā ʻoe ma o ka vein.

No ke aha i hoʻohana ʻia ai ka Necitumumab?

Ua ʻae ʻia ʻo Necitumumab e mālama i ka squamous non-small cell lung cancer i laha i nā ʻāpana ʻē aʻe o kou kino. E kauoha wale kāu kauka i kēia lāʻau lapaʻau inā loaʻa i kāu maʻi maʻi kēia ʻano cell squamous.

E loaʻa pinepine iā ʻoe ka necitumumab i hui pū ʻia me nā lāʻau chemotherapy i kapa ʻia ʻo gemcitabine a me cisplatin. ʻO kēia hui pū ʻana e hana maikaʻi pinepine ma mua o ka chemotherapy wale nō no ka mea e hoʻouka ana kēlā me kēia lāʻau lapaʻau i ka maʻi ma nā ʻano like ʻole.

E hōʻoia ana kāu kauka oncologist i ka pono o ka necitumumab no kou kūlana ma o nā hoʻokolohua like ʻole. Hiki i kēia mau mea ke komo i nā laʻana ʻiʻo mai kāu maʻi ʻaʻai a me nā scans e ʻike ai i ka laulā o ka maʻi.

Pehea e Hana ai ka Necitumumab?

Hana ʻo Necitumumab ma ka pale ʻana i kahi protein i kapa ʻia ʻo EGFR (epidermal growth factor receptor) e noho ana ma luna o nā pūnaewele maʻi ʻaʻai. Kōkua maʻamau kēia protein i nā pūnaewele e ulu a māhele, akā pinepine ka nui o nā pūnaewele maʻi ʻaʻai.

Ke pili ka necitumumab i ka EGFR, ua like ia me ka waiho ʻana i kahi laka ma ka puka e hoʻohana ai nā pūnaewele maʻi ʻaʻai e loaʻa ai nā hōʻailona ulu. Kōkua kēia i ka hoʻolohi a i ʻole ka hoʻōki ʻana i ka ulu ʻana o ka maʻi ʻaʻai a me ka laha ʻana i nā wahi hou o kou kino.

Ua manaʻo ʻia kēia lāʻau lapaʻau he lāʻau lapaʻau maʻi ʻaʻai ikaika. ʻOiai ʻaʻole ikaika e like me kekahi mau lāʻau chemotherapy, pono nō ia i ka nānā pono ʻana a hiki ke hana i nā hopena ʻaoʻao koʻikoʻi e nānā pono ai kāu hui lapaʻau.

Pehea wau e Lawe ai i ka Necitumumab?

E loaʻa iā ʻoe ka necitumumab ma o ka IV infusion e lawe ana ma kahi o 60 mau minuke. E hāʻawi kāu hui mālama ola iā ʻoe i kēia lāʻau lapaʻau ma kahi kikowaena lapaʻau maʻi ʻaʻai kahi e hiki ai iā lākou ke nānā pono iā ʻoe i ka wā a ma hope o ka infusion.

Ma mua o kēlā me kēia lapaʻau, e loaʻa paha iā ʻoe nā lāʻau lapaʻau e kōkua i ka pale ʻana i nā hopena maʻi. Hiki i kēia mau mea ke komo i nā antihistamines e like me Benadryl a i ʻole nā steroids e hōʻemi i ka manawa o nā hopena infusion.

ʻAʻole pono ʻoe e pale i ka meaʻai ma mua o kāu lapaʻau necitumumab, akā ʻo ka noho ʻana i ka wai maikaʻi ma ka inu ʻana i ka wai nui hiki ke kōkua i kou kino e hana i ka lāʻau lapaʻau me ka maikaʻi. E hāʻawi pū kāu kahu hānai iā ʻoe i nā wai IV i ka wā o ka lapaʻau.

Hahai maʻamau ka papa manawa infusion i kahi ʻano kahi e loaʻa ai iā ʻoe ka necitumumab i nā lā 1 a me 8 o kēlā me kēia pōʻai lapaʻau 21-lā. E hoʻoponopono kāu kauka i kēia manawa ma muli o ka maikaʻi o kāu pane ʻana i ka lapaʻau a me kou manaʻo.

Pehea ka lōʻihi e lawe ai au i ka Necitumumab?

He ʻokoʻa ka lōʻihi o ka mālama ʻana me necitumumab mai kēlā kanaka i kēia kanaka. Loaʻa i kekahi poʻe ia no nā mahina he nui, a ʻo nā mea ʻē aʻe e hoʻomau paha no hoʻokahi makahiki a ʻoi aku paha inā e hana maikaʻi ana a hiki ke mālama ʻia nā hopena ʻaoʻao.

E nānā mau kāu oncologist i ka pane ʻana o kāu maʻi maʻi ma o nā scans a me nā hoʻokolohua koko. Inā hoʻomaka hou ka maʻi maʻi e ulu a i ʻole inā lilo nā hopena ʻaoʻao i mea paʻakikī loa ke mālama ʻia, e kūkākūkā kāu kauka i ka hoʻōki ʻana i ka necitumumab a me ka ʻimi ʻana i nā koho lapaʻau ʻē aʻe.

Aia nā hoʻoholo lapaʻau i nā mea he nui me ke ʻano o kou manaʻo, nā hopena scan, a me kou olakino holoʻokoʻa. E kamaʻilio ʻoiaʻiʻo kāu hui lapaʻau me ʻoe e pili ana i ka hoʻomau ʻana a i ʻole ka hoʻololi ʻana i kāu hoʻolālā lapaʻau i ka wā e hala ana.

He aha nā hopena ʻaoʻao o Necitumumab?

E like me ka hapa nui o nā lāʻau lapaʻau maʻi maʻi, hiki i ka necitumumab ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole i ʻike nā kānaka a pau iā lākou ma ke ala like. ʻO ka hoʻomaopopo ʻana i ka mea e hiki ke hana hiki ke kōkua iā ʻoe e mākaukau a ʻike i ka manawa e hoʻokaʻaʻike aku ai i kāu hui mālama ola.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai me nā pilikia ʻili, nā ʻeha waha, a me nā loli i kāu pae koko e nānā ai kāu kauka ma o nā hoʻokolohua lab maʻamau.

Nā hopena ʻaoʻao maʻamau

Hana ʻia kēia mau hopena ʻaoʻao i nā kānaka he nui e lawe ana i ka necitumumab, akā hiki ke mālama ʻia me ka mālama kūpono a me ka nānā ʻana:

• Pilikia ʻili a i ʻole nā puʻupuʻu e like me ka ʻāʻī, ʻoi loa ma kou maka a me kou umauma
• ʻIli maloʻo, ʻili e hiki ke māhā a i ʻole e ʻili
• Nā ʻeha waha a i ʻole ka ʻeha i ka wā e ʻai ai
• Pilikia a i ʻole nā ʻōpala palupalu
• Luhi a i ʻole ka manaʻo e luhi ana ma mua o ka maʻamau
• Nā loli i kāu pae magnesium
• Nā pilikia kui e like me ka maʻi a i ʻole ka ʻeha a puni nā moena kui

Loaʻa i kāu hui mālama ola ka ʻike i ka mālama ʻana i kēia mau hopena ʻaoʻao a hiki ke hāʻawi i nā lāʻau lapaʻau a i ʻole nā ʻōlelo aʻoaʻo e kōkua iā ʻoe e ʻoluʻolu. Hoʻomaikaʻi ka hapa nui o kēia mau pilikia i ka manawa a i ʻole ke pau ka lapaʻau.

Nā hopena ʻaoʻao koʻikoʻi

ʻOiai ʻaʻole maʻamau, pono kekahi mau hopena ʻaoʻao i ka mālama olakino koke. ʻO ka ʻike ʻana i kēia mau hōʻailona hōʻailona e kōkua iā ʻoe e loaʻa ke kōkua wikiwiki inā pono:

• Nā hopena ʻili koʻikoʻi me ka ʻōpū a i ʻole ka ʻōpala ākea
• Nā hōʻailona o ka maʻi e like me ke kuni, nā anu, a i ʻole ka luhi ʻole
• Ka maʻi maʻi koʻikoʻi ʻaʻole e hoʻomaikaʻi me ka lāʻau lapaʻau
• Nā koko koko e hoʻoulu ai i ka pehu wāwae, ka ʻeha o ka umauma, a i ʻole ka hanu ʻana
• Nā pilikia o ka puʻuwai me ka puʻuwai ʻole a i ʻole ka ʻeha o ka umauma
• Nā hopena maʻi koʻikoʻi i ka wā o ka hoʻokomo ʻana

Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, ​​e hoʻokaʻaʻike koke i kāu hui oncology a i ʻole e hele i ka lumi pilikia. ʻO ka loaʻa ʻana o kahi hoʻolālā no ka hiki ʻana i kāu hui lapaʻau ma hope o nā hola hiki ke hāʻawi i ka maluhia o ka noʻonoʻo.

Nā hopena ʻaoʻao kakaʻikahi akā koʻikoʻi

Loaʻa kekahi mau hopena ʻaoʻao i ka liʻiliʻi akā pono nō naʻe ka nānā ʻana. E nānā kāu hui lapaʻau i kēia mau mea ma o nā loiloi maʻamau a me nā hoʻokolohua:

• Nā hāʻule nui i nā helu koko e hoʻonui ai i ka pilikia o ka maʻi
• Nā pilikia o ka puʻupaʻa e hiki ke hoʻololi i ke ʻano o kāu mimi
• Ka mumū o ka māmā e hoʻoulu ai i ka ʻū mau a i ʻole nā ​​pilikia hanu
• Nā kaulike electrolyte koʻikoʻi e pili ana i ka puʻuwai
• Nā pilikia o ka maka me nā loli ʻike a i ʻole ka ʻeha

Kōkua ka nānā mau ʻana i ka hopu ʻana i kēia mau pilikia i ka wā mua ke maʻalahi lākou e mālama. E hoʻoponopono kāu hui mālama ola i kāu hoʻolālā lapaʻau inā e ulu kekahi mau loli e pili ana.

ʻO wai ka mea pono ʻole e lawe iā Necitumumab?

ʻAʻole kūpono ʻo Necitumumab no nā mea a pau me ka maʻi maʻi maʻi māmā. E nānā pono kāu kauka i kāu mōʻaukala olakino a me ke kūlana olakino o kēia manawa ma mua o ka ʻōlelo ʻana i kēia lāʻau.

ʻAʻole pono ka poʻe me nā ʻano maʻi maʻi māmā ʻole e loaʻa iā necitumumab no ka mea e hōʻike ana nā haʻawina ʻaʻole ia e kōkua a hiki ke hōʻeha i ka pōʻino ma mua o ka pōmaikaʻi i kēia mau hihia. E hoʻāʻo kāu kauka i kāu ʻiʻo maʻi e hōʻoia i ke ʻano squamous ma mua o ka hoʻomaka ʻana i ka lāʻau.

Inā he pilikia nui kou i ka puʻuwai, ka maʻi kīkī, a i ʻole nā maʻi ʻē aʻe, hiki i kāu kauka ke koho i nā koho lapaʻau like ʻole. E noʻonoʻo nō hoʻi lākou i nā lāʻau lapaʻau āu e lawe nei i kēia manawa e pale aku i nā pilina weliweli.

He mea nui ka hāpai ʻana a me ka hānai ʻana i ka waiū. Hiki i ka Necitumumab ke hōʻeha i nā pēpē e ulu ana, no laila pono ʻoe e hoʻohana i ka mana hānau pono i ka wā o ka lapaʻau a no kekahi mau mahina ma hope inā hiki iā ʻoe ke hāpai.

Inoa Brand Necitumumab

Kūʻai ʻia ʻo Necitumumab ma lalo o ka inoa brand Portrazza. Hiki iā ʻoe ke ʻike i kekahi inoa ma kāu mau moʻolelo lapaʻau, nā palapala ʻinikua, a i ʻole nā lepili lāʻau.

Inā kuhikuhi kāu kauka iā ia ma ke ʻano he necitumumab a i ʻole Portrazza, ke kamaʻilio nei lākou e pili ana i ka lāʻau lapaʻau like. Hōʻike ʻia nā inoa ʻelua ma nā kauoha lapaʻau kūhelu a me nā hoʻolālā lapaʻau.

Nā Koho ʻē aʻe o Necitumumab

Inā ʻaʻole kūpono ka necitumumab iā ʻoe a i ʻole e pau ka hana pono ʻana, aia kekahi mau koho lapaʻau ʻē aʻe no ka maʻi maʻi ʻaʻai ʻāʻī ʻole. E kūkākūkā kāu oncologist i kēia mau koho ʻē aʻe e pili ana i kāu kūlana kikoʻī.

Hana ʻokoʻa nā lāʻau lapaʻau i manaʻo ʻia e like me ka pembrolizumab (Keytruda) a i ʻole nivolumab (Opdivo) ma ke kōkua ʻana i kāu ʻōnaehana pale e hakakā i ka maʻi maʻi. Ua hōʻike kēia mau lāʻau immunotherapy i ka hoʻohiki ʻana i ka mālama ʻana i ka maʻi maʻi ʻaʻai, ʻoiai ua hana maikaʻi lākou i nā kūlana like ʻole.

He mea nui nā hui chemotherapy kuʻuna. Hiki i kāu kauka ke ʻōlelo aku i ka carboplatin a me ka paclitaxel a i ʻole nā hui ʻē aʻe e pili ana i kou olakino holoʻokoʻa a me nā lapaʻau mua.

Hāʻawi nā hoʻokolohua lapaʻau i ke komo ʻana i nā lapaʻau hoʻokolohua hou e hiki ke lilo i nā therapies maʻamau i ka wā e hiki mai ana. Hiki i kāu oncologist ke kōkua iā ʻoe e ʻimi inā kūpono kekahi mau hoʻokolohua i kēia manawa no kou kūlana.

Ua ʻoi aku ka maikaʻi o Necitumumab ma mua o Cetuximab?

ʻO Necitumumab a me cetuximab nā mea pale i ka EGFR, akā hoʻohana ʻia lākou no nā ʻano maʻi ʻaʻai like ʻole. Hoʻohana nui ʻia ʻo Cetuximab no nā maʻi ʻaʻai colorectal a me ke poʻo a me ka ʻāʻī, ʻoiai ua ʻae ʻia ʻo necitumumab no ka maʻi ʻaʻai māmā squamous.

He paʻakikī nā hoʻohālikelike pololei ma waena o kēia mau lāʻau lapaʻau no ka mea e mālama lākou i nā ʻano maʻi ʻaʻai like ʻole. Ua aʻo nui ʻia kēlā me kēia mea i loko o kāna mau ʻano maʻi ʻaʻai i ʻae ʻia a ua hōʻike i nā pōmaikaʻi nui ke hoʻohana pono ʻia.

Na kāu oncologist e koho i ka lāʻau lapaʻau kūpono loa no kāu ʻano maʻi ʻaʻai a me ke kūlana. ʻAʻole pili ka hoʻoholo i ka lāʻau lapaʻau

Inā loaʻa iā ʻoe nā hōʻailona e like me ka pilikia o ka hanu ʻana, ka paʻa ʻana o ka umauma, ka ʻūhū nui, a i ʻole ka wili ʻana i ka wā o kāu infusion, e haʻi koke i kāu kahu. Ua aʻo ʻia lākou e ʻike a mālama koke i nā hopena infusion.

Hiki i kāu hui lapaʻau ke hoʻolohi a hoʻōki paha i ka infusion no ka manawa a hāʻawi iā ʻoe i nā lāʻau lapaʻau e kōkua ai i ka hopena. Hiki ke mālama ʻia ka hapa nui o nā hopena infusion, a hiki i ka nui o nā kānaka ke hoʻomau i ka mālama ʻana me nā hana kūpono.

Q4. I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka necitumumab?

Aia ka hoʻoholo e hooki i ka necitumumab i ka maikaʻi o kāna hana ʻana a me ka maikaʻi o kou ʻae ʻana i ka lāʻau lapaʻau. E loiloi mau kāu oncologist i kāu pane ma o nā scans a me nā hoʻokolohua koko e hana i kēia hoʻoholo.

Hiki iā ʻoe ke hooki i ka necitumumab inā holomua kāu maʻi maʻi me ka mālama ʻana, inā lilo nā hopena ʻaoʻao i mea paʻakikī loa ke mālama ʻia, a i ʻole inā loaʻa iā ʻoe kahi pane maikaʻi a ʻōlelo kāu kauka i kahi hoʻomaha lapaʻau. Hana mau ʻia kēia mau hoʻoholo ma waena ou a me kāu hui mālama ola.

Q5. Hiki iaʻu ke lawe i nā lāʻau lapaʻau ʻē aʻe i ka wā e loaʻa ana ka necitumumab?

Hiki ke lawe palekana ʻia nā lāʻau lapaʻau he nui me ka necitumumab, akā hiki i kekahi ke launa pū a hoʻonui i nā hopena ʻaoʻao. E haʻi mau i kāu oncologist e pili ana i nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā huaora āu e lawe nei.

E nānā kāu hui mālama ola i kāu papa inoa lāʻau lapaʻau ma mua o ka hoʻomaka ʻana i ka necitumumab a hiki ke hoʻoponopono i nā dosages a i ʻole ka manawa o nā lāʻau ʻē aʻe. E mālama i kahi papa inoa hou o kāu mau lāʻau lapaʻau a pau a lawe mai i kēlā me kēia manawa.