He aha ka Ocriplasmin: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He mea hoʻokomo maka kūikawā ʻo Ocriplasmin e kōkua i ka mālama ʻana i kahi maʻi i kapa ʻia ʻo vitreomacular adhesion. Hana kēia lāʻau lapaʻau ma ka hoʻoheheʻe ʻana i ka pilina maʻamau ma waena o nā ʻāpana ʻelua o kou maka - ka gel vitreous a me ka macula (ka ʻāpana o kou retina e kuleana no ka ʻike maopopo a me ka waena).

Inā ua ʻōlelo kāu kauka iā ocriplasmin, e hana ana paha ʻoe me nā loli ʻike e pili ana i kāu mau hana i kēlā me kēia lā. Hōʻike kēia lapaʻau i kahi holomua nui i ka mālama maka, e hāʻawi ana i kahi koho liʻiliʻi i ka ʻoki maka kuʻuna no kekahi mau maʻi.

He aha ka Ocriplasmin?

ʻO Ocriplasmin kahi lāʻau lapaʻau i hoʻokumu ʻia i ka enzyme i hoʻokomo pololei ʻia i loko o kou maka e mālama i ka vitreomacular adhesion. He protein i hoʻomaʻemaʻe ʻia e hana e like me nā ʻūlū molecular, e wāwahi pono ana i nā protein e hana i nā pilina makemake ʻole i kou maka.

No kahi enzyme nui i kapa ʻia ʻo plasmin ka lāʻau lapaʻau, a hana maoli kou kino. Ua hoʻololi nā ʻepekema i kēia enzyme e hana i mea i manaʻo nui ʻia a maikaʻi hoʻi no ka mālama ʻana i nā maʻi maka. E noʻonoʻo iā ia he mea hana pololei i hoʻolālā ʻia no ka ʻiʻo maka palupalu.

He mea hou kēia lapaʻau i ka honua o ka mālama maka, ua ʻae ʻia e ka FDA i ka makahiki 2012. Kūʻai ʻia ma lalo o ka inoa inoa ʻo Jetrea a hōʻike i kahi holomua nui no ka poʻe i loaʻa nā koho lapaʻau palena.

No ke aha e hoʻohana ʻia ai ʻo Ocriplasmin?

Hoʻomaʻamaʻa ʻo Ocriplasmin i ka vitreomacular adhesion, kahi maʻi kahi e pili ai ka mea like me ka gel i kou maka (vitreous) i kāu macula. Hiki i kēia pilina makemake ʻole ke kumu i nā pilikia ʻike, me ka ʻike waena i ka noe a i ʻole ka distorted.

Hiki i kāu kauka ke ʻōlelo aku i kēia lapaʻau inā e ʻike ana ʻoe i nā hōʻailona e like me nā laina pololei e ʻike ʻia ana he nalu, ka pilikia i ka heluhelu ʻana, a i ʻole nā pilikia me nā hana kikoʻī. Hoʻopilikia maʻamau ke kūlana i ka poʻe ma luna o 65, akā hiki ke hana i kēlā me kēia makahiki.

I kekahi mau hihia, hiki i ka ocriplasmin ke kōkua i nā lua macular liʻiliʻi - nā waimaka liʻiliʻi i ka macula e hiki ke hoʻopilikia nui i kāu ʻike waena. Eia naʻe, ʻoi aku ka maikaʻi no nā lua ma lalo o 400 micrometers ke anawaena.

Pehea e hana ai ʻo Ocriplasmin?

Hana ʻo Ocriplasmin ma ka wāwahi ʻana i nā protein kikoʻī e paʻa ana i ka gel vitreous i kāu macula. Hoʻopaʻa ia i nā protein i kapa ʻia ʻo fibronectin a me laminin, ʻo ia nā mea nui e hana ana i kēia adhesion abnormal.

Ke hoʻokomo ʻia i loko o kou maka, hoʻomaka ka lāʻau lapaʻau e hana i loko o nā hola a i nā lā. Hoʻoheheʻe maoli ia i ka

ʻAʻole pono ʻoe e hoʻokē ʻai ma mua o ke kaʻina hana, a hiki iā ʻoe ke ʻai maʻamau ma mua. Eia naʻe, pono ʻoe e hoʻonohonoho i kekahi e hoʻokele iā ʻoe i ka home, no ka mea, e pōpō iki a ʻoluʻolu ʻole paha kou ʻike ma hope o ka injection.

Ma hope o ka injection, e kauoha paha kāu kauka i nā kulu maka antibiotic e hoʻohana no kekahi mau lā. E hoʻonohonoho pū lākou i nā manawa e nānā ai i kāu holomua a hōʻoia i ka hana pono ʻana o ka lāʻau lapaʻau.

Pehea ka lōʻihi e lawe ai au i ka Ocriplasmin?

Hāʻawi ʻia ʻo Ocriplasmin ma ke ʻano he injection hoʻokahi, a ʻaʻole pono ka hapa nui o nā maʻi e hana hou i nā lāʻau lapaʻau. Ke hoʻomau nei ka lāʻau lapaʻau i ka hana ʻana i kou maka no kekahi mau pule ma hope o ka injection, e hoʻoheheʻe mālie ana i ka adhesion abnormal.

E nānā kāu kauka i kāu holomua ma o nā hoʻokolohua maka maʻamau i nā mahina e hiki mai ana. Hana pinepine ʻia kēia mau manawa ma hoʻokahi pule, hoʻokahi mahina, a me ʻekolu mahina ma hope o ka injection. Pono paha kekahi mau maʻi i nā mea hou aʻe e pili ana i kā lākou pane i ka lāʻau lapaʻau.

Inā ʻaʻole i loaʻa i ka injection mua nā hopena i makemake ʻia ma hope o ʻekolu mahina, hiki i kāu kauka ke kūkākūkā i nā lāʻau lapaʻau ʻē aʻe. Eia naʻe, ʻaʻole maʻamau ka hana hou ʻana o nā injections o ocriplasmin, no ka mea, hana ka lāʻau lapaʻau i nā mahina mua a i ʻole e noʻonoʻo ʻia nā ala ʻē aʻe.

He aha nā hopena ʻaoʻao o Ocriplasmin?

ʻIke ka hapa nui o nā kānaka i kekahi mau hopena ʻaoʻao ma hope o ka injection ocriplasmin, he mea maʻamau loa ia i ka wā e hoʻoponopono ai kou maka i ka lāʻau lapaʻau. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e mākaukau a emi ʻole ka hopohopo e pili ana i ke kaʻina hana.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia:

• ʻEha maka a i ʻole ka ʻoluʻolu (maʻamau ka maʻalahi a hoʻoponopono i loko o kekahi mau lā)
• Ke ʻike nei i nā kiko lana liʻiliʻi a i ʻole

  E hoʻomaikaʻi maʻamau kēia mau hopena i loko o hoʻokahi pule a he mau hōʻailona ia e pane ana kou maka i ka lapaʻau. E hāʻawi ana kāu kauka i nā ʻōlelo kikoʻī e pili ana i ka mālama ʻana i kekahi ʻoluʻolu.

  ʻAʻole maʻamau nā hopena ʻaoʻao koʻikoʻi, akā pono lākou i ka mālama olakino koke. Hiki i kēia mau pilikia laha ʻole ke komo:

  • ʻEha maka nui ʻaʻole e hoʻomaikaʻi me nā mea hōʻoluʻolu ʻeha ma luna o ka pāʻālua
  • Ka nalowale ʻana o ka ʻike koke a koʻikoʻi
  • Nā kukui uila a i ʻole ka piʻi koke ʻana o nā mea lana
  • Nā hōʻailona o ka maʻi e like me ka ʻulaʻula nui, ka hoʻokuʻu ʻana, a i ʻole ke kuni
  • Hoʻokaʻawale ʻana o ka retina (e pili ana i ka liʻiliʻi ma mua o 1% o nā mea maʻi)
  • Piʻi nui i ke kaomi maka

  ʻOiai he mea laha ʻole kēia mau pilikia koʻikoʻi, he mea nui e hoʻokaʻaʻike koke i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona. Hiki i ka lapaʻau wikiwiki ke pale i nā pilikia ʻike mau.

  ʻO wai ka mea pono ʻole e lawe iā Ocriplasmin?

  ʻAʻole kūpono ʻo Ocriplasmin no nā mea a pau me ka pili vitreomacular. E loiloi pono kāu kauka i kou kūlana kikoʻī e hoʻoholo ai inā he moho maikaʻi ʻoe no kēia lapaʻau.

  ʻAʻole pono ʻoe e loaʻa iā ocriplasmin inā loaʻa iā ʻoe:

  • He maʻi maka ikaika a i ʻole ka mumū
  • Nā lua macular nui (ʻoi aku ma mua o 400 micrometers)
  • Myopia kiʻekiʻe (nearsightedness koʻikoʻi) me nā loli retinal pili
  • ʻO ka ʻoki maka hou a i ʻole ka trauma
  • Nā maʻi retinal kekahi e pili ana i ka macula
  • Retinopathy diabetic proliferative me ka ulu ʻana o nā kīʻaha koko ikaika

  E noʻonoʻo pū kāu kauka i kou olakino holoʻokoʻa a me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei. ʻOiai ua hoʻokomo pololei ʻia ʻo ocriplasmin i loko o ka maka, he mea nui e kūkākūkā i kāu mōʻaukala olakino piha e hōʻoia i ka palekana o ka lapaʻau iā ʻoe.

  Pono nā wahine hāpai a me nā wahine e hānai ana i ka waiū e kūkākūkā i nā pilikia a me nā pōmaikaʻi me kā lākou kauka, no ka mea, he ʻike palena ʻia e pili ana i nā hopena o ocriplasmin i ka wā hāpai a me ka hānai ʻana.

  Inoa Lama Ocriplasmin

  Ua kūʻai ʻia ʻo Ocriplasmin ma lalo o ka inoa lama ʻo Jetrea ma ʻAmelika Hui Pū ʻIa a me nā ʻāina ʻē aʻe he nui. ʻO kēia wale nō ke ʻano o ka ocriplasmin i loaʻa no ke kālepa ʻana no ka mālama ʻana i ka pili vitreomacular.

  Hana ʻia ʻo Jetrea e Oxurion (i kapa ʻia ʻo ThromboGenics), he hui lāʻau lapaʻau Belgian e loea ana i nā lāʻau lapaʻau maka. Hele mai ka lāʻau lapaʻau i loko o kahi vial hoʻohana hoʻokahi i loaʻa iā 0.1 mL o ka hopena.

Hiki i kāu kauka ke kuhikuhi i ka lāʻau lapaʻau ma kekahi inoa - ocriplasmin a i ʻole Jetrea - akā he lāʻau lapaʻau like lākou. Hoʻohana pinepine ʻia ka inoa lama i nā wahi lapaʻau a me nā palapala ʻinikua.

Nā Koho ʻē aʻe o Ocriplasmin

Inā ʻaʻole kūpono ʻo ocriplasmin no kou maʻi a i ʻole ʻaʻole i hāʻawi i nā hopena i makemake ʻia, aia kekahi mau lāʻau lapaʻau ʻē aʻe. E kōkua kāu kauka iā ʻoe e hoʻomaopopo i ke koho e hana maikaʻi loa no kāu kūlana.

ʻO ka mea nui ʻo vitrectomy, kahi hana ʻoki kahi e wehe ai kāu kauka lapaʻau i ka gel vitreous mai kou maka a pani iā ia me kahi hopena paʻakai. ʻOi aku ka invasive o kēia ʻoki ma mua o ka injection ocriplasmin akā he kiʻekiʻe ka helu holomua no ka mālama ʻana i ka pili vitreomacular.

No kekahi poʻe maʻi, kūpono paha ka nānā pono ʻana, ʻoiai inā maʻalahi nā hōʻailona. Nui nā hihia o ka pili vitreomacular e hoʻoponopono iā lākou iho i ka manawa me ka ʻole o ka lāʻau lapaʻau.

Ke noiʻi ʻia nei nā lāʻau lapaʻau ʻē aʻe no nā kūlana like, akā ʻo ocriplasmin ka lāʻau lapaʻau wale nō i ʻae ʻia e ka FDA no ka mālama ʻana i ka pili vitreomacular. Hiki i kāu loea retinal ke kūkākūkā i ke ala e kūpono loa ai no kāu hihia.

ʻOi aku ka maikaʻi o Ocriplasmin ma mua o ke ʻoki vitrectomy?

Loaʻa i ka ʻoki ocriplasmin a me ka vitrectomy nā pōmaikaʻi like ʻole, a ʻo ke koho maikaʻi loa e hilinaʻi ana i kāu kūlana a me nā makemake. ʻAʻole ʻoi aku ka maikaʻi o kekahi lāʻau lapaʻau - lawelawe lākou i nā maʻi a me nā kūlana like ʻole.

Hāʻawi ʻo Ocriplasmin i nā pōmaikaʻi he nui ma ke ʻano he koho liʻiliʻi. He mau minuke wale nō ka hana injection, ʻaʻole pono ka anesthesia maʻamau, a he manawa hoʻōla pōkole. Hiki iā ʻoe ke hoʻi i nā hana maʻamau i loko o kekahi mau lā, a ʻaʻohe pilikia o ka hana ʻana o ka cataract, hiki ke hana ma hope o ka vitrectomy.

Eia naʻe, ʻoi aku ka kiʻekiʻe o ka holomua o ka ʻoki vitrectomy, e hana ana ma kahi o 90-95% o nā hihia i hoʻohālikelike ʻia me ka 25-40% o ka holomua o ocriplasmin. Hiki nō hoʻi i ke ʻoki ke ʻae i kāu kauka e kamaʻilio i nā pilikia maka ʻē aʻe i ka manawa like a hāʻawi i nā hopena i ʻike ʻia.

E noʻonoʻo kāu kauka i nā mea e like me ka nui o kekahi lua macular, ka ikaika o ka vitreomacular adhesion, kou makahiki, a me kou olakino holoʻokoʻa i ka wā e ʻōlelo ai i ka lāʻau lapaʻau. Nui nā kauka e hoʻāʻo mua i ka ocriplasmin ke kūpono, no ka mea, ʻaʻole ia he mea hoʻopilikia a hiki ke pale i ka pono o ke ʻoki.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Ocriplasmin

He Palekana ʻo Ocriplasmin no ka poʻe me ka maʻi diabetes?

Hiki ke palekana ʻo Ocriplasmin no ka poʻe me ka maʻi diabetes, akā pono kāu kauka e loiloi pono i kou kūlana maka kikoʻī. Inā loaʻa iā ʻoe ka retinopathy diabetic, ʻo ia hoʻi ke ʻano proliferative me ka ulu ʻana o nā kīʻaha koko hou, ʻaʻole paha e ʻōlelo ʻia ka ocriplasmin.

Hiki i ka maʻi diabetes ke hoʻopilikia i kou retina ma nā ʻano e hoʻemi ai ka pono o ka ocriplasmin a i ʻole ka pilikia. E hana kāu kauka i kahi hoʻokolokolo maka piha a hiki ke kauoha i nā hoʻokolohua kiʻi kūikawā e loiloi inā kūpono ka ocriplasmin iā ʻoe.

Inā loaʻa iā ʻoe ka maʻi diabetes i mālama maikaʻi ʻia me ka ʻole o nā loli retinal nui, hiki nō ke koho ʻo ocriplasmin. ʻO ke kī ka loaʻa ʻana o kahi kūkākūkā ʻoiaʻiʻo me kāu loea retinal e pili ana i kāu mālama ʻana i ka maʻi diabetes a me ke olakino maka holoʻokoʻa.

He aha kaʻu e hana ai inā loaʻa iaʻu ka ʻeha nui ma hope o ka injection Ocriplasmin?

E kāhea koke i kāu kauka inā loaʻa iā ʻoe ka ʻeha nui o ka maka ʻaʻole e hoʻomaikaʻi me nā mea hōʻoluʻolu ʻeha i kūʻai ʻia a i ʻole e ʻoi aku ka ʻino i ka manawa. ʻOiai he mea maʻamau ka ʻoluʻolu ma hope o ka injection, hiki i ka ʻeha nui ke hōʻike i kahi pilikia e pono ai ka mālama koke.

Hiki i kāu kauka ke nānā i kou maka e nānā i nā hōʻailona o ka maʻi, ka piʻi ʻana o ke kaomi maka, a i ʻole nā pilikia ʻē aʻe. Hiki iā lākou ke kuhikuhi i nā lāʻau lapaʻau ʻeha ikaika a i ʻole nā lāʻau lapaʻau hou aʻe ma muli o kā lākou mea i ʻike ai.

Mai kali e ʻike inā e hoʻomaikaʻi ka ʻeha nui iā ia iho. Hiki i ka hana mua ke pale i nā pilikia koʻikoʻi a kōkua i ka mālama ʻana i kou ʻike. Loaʻa i ka hapa nui o nā keʻena maka nā helu pili ma hope o nā hola no nā pilikia wikiwiki.

I ka manawa hea wau e ʻike ai inā e hana ana ʻo Ocriplasmin?

Hiki iā ʻoe ke hoʻomaka e ʻike i nā hoʻomaikaʻi ʻana i kou ʻike i loko o nā pule mua ma hope o ka injection, ʻoiai e ʻike kekahi poʻe maʻi i nā loli ma mua. Ke hoʻomau nei ka lāʻau lapaʻau no kekahi mau pule, no laila mai hopohopo inā ʻaʻole ʻoe e ʻike i nā hopena koke.

E nānā kāu kauka i kāu holomua ma o nā manawa hālāwai maʻamau, i hoʻonohonoho ʻia i hoʻokahi pule, hoʻokahi mahina, a me ʻekolu mahina ma hope o ka injection. E hoʻohana lākou i nā hoʻokolohua kiʻi kūikawā e ʻike inā e hoʻokuʻu ana ka vitreomacular adhesion.

Ma ka hōʻailona ʻekolu mahina, hiki i kāu kauka ke hoʻoholo inā ua holomua ka lāʻau lapaʻau. Inā ʻaʻole i loaʻa i ka ocriplasmin nā hopena i makemake ʻia i kēlā manawa, e kūkākūkā lākou i nā koho lapaʻau ʻē aʻe me ʻoe.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o Ocriplasmin?

ʻAʻole pono ʻoe e kalaiwa koke ma hope o ka loaʻa ʻana o ka injection ocriplasmin, no ka mea, hiki ke pōʻeleʻele a ʻoluʻolu ʻole paha kou ʻike. E hoʻolālā e loaʻa i kekahi e kalaiwa iā ʻoe i ka home mai ka manawa.

Hiki i ka hapa nui o nā mea maʻi ke hoʻomau i ke kalaiwa i loko o hoʻokahi a ʻelua paha lā, i ka wā i maopopo ai ko lākou ʻike a ua pau ka ʻoluʻolu. Eia naʻe, pono ʻoe e kali a hiki i kou manaʻo e palekana ana kou ʻike no ke kalaiwa ʻana a hiki iā ʻoe ke heluhelu maopopo i nā hōʻailona alanui.

E hāʻawi kāu kauka i nā ʻōlelo kikoʻī e pili ana i ka manawa e hiki ai iā ʻoe ke hoʻi i ke kalaiwa ʻana ma muli o ke ʻano o ka pane ʻana o kou maka i ka lāʻau. Inā he hopohopo kāu e pili ana i kou ʻike ma hope o ka injection, mai kānalua e hoʻokaʻaʻike i ke keʻena o kāu kauka.

He mau hopena lōʻihi anei o Ocriplasmin?

ʻAʻole ʻike ka hapa nui o nā maʻi i nā hopena ʻaoʻao lōʻihi mai ka lāʻau ocriplasmin. Ua hoʻolālā ʻia ka lāʻau lapaʻau e hana no ka manawa pōkole a laila e hoʻomaʻemaʻe ʻia mai kou maka maoli i ka manawa.

Hiki i kekahi poʻe maʻi ke ʻike i nā loli mau i kā lākou floaters a i ʻole ka maikaʻi o ka ʻike ʻana, akā pili pinepine kēia mau mea i ke kūlana ma lalo o ka maʻi ma mua o ka lāʻau lapaʻau ponoʻī. ʻO ka pahuhopu ka hoʻomaikaʻi ʻana i kou ʻike holoʻokoʻa a me ka maikaʻi o ke ola.

E hoʻomau kāu kauka i ka nānā ʻana i ke olakino o kou maka i nā manawa e hiki mai ana e hōʻoia ʻaʻohe hopena lōʻihi i manaʻo ʻole ʻia. Inā ʻike ʻoe i nā loli e pili ana i kou ʻike i nā mahina a i ʻole nā makahiki ma hope o ka lāʻau lapaʻau, e hoʻokaʻaʻike i kāu mea mālama maka no ka loiloi.