He aha ka Palonosetron: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ka Palonosetron i hāʻawi ʻia ma o ka laina IV (intravenous) e pale ai i ka nausea a me ka luaʻi. Hoʻolālā ʻia ia e kōkua i ka poʻe e loaʻa ana i ka chemotherapy a i ʻole ke ʻoki ʻana e hoʻoulu pinepine i kēia mau hōʻailona hōʻoluʻolu ʻole. Hana kēia lāʻau lapaʻau ma ka pale ʻana i kekahi mau hōʻailona i kou lolo e hōʻoluʻolu ʻole ai ʻoe i kou ʻōpū.

He aha ka Palonosetron?

No ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo 5-HT3 receptor antagonists ka Palonosetron, he mea paʻakikī ke kani ʻana akā ʻo ia hoʻi ka pale ʻana i nā ʻelele kemika kikoʻī i kou kino. Hiki i kēia mau ʻelele, i kapa ʻia ʻo serotonin, ke hoʻoulu i ka nausea a me ka luaʻi ke hoʻokuʻu ʻia lākou i nā mea nui i ka wā o nā lāʻau lapaʻau. E noʻonoʻo i ka palonosetron ma ke ʻano he pale pale e pale ai i kēia mau hōʻailona makemake ʻole mai ka hiki ʻana i ka ʻāpana o kou lolo e hoʻomalu ai i ka nausea.

Loaʻa wale kēia lāʻau lapaʻau ma ke ʻano he injection a pono e hāʻawi ʻia e kekahi ʻoihana mālama ola i kahi hoʻonohonoho lapaʻau. ʻAʻole hiki iā ʻoe ke lawe i ka palonosetron ma ka home a i ʻole ma ka waha - ua hoʻomākaukau ʻia e hana ma o kou kahe koko ke lawelawe ʻia intravenously.

No ke aha e hoʻohana ʻia ai ka Palonosetron?

Hoʻohana nui ʻia ka Palonosetron e pale i ka nausea a me ka luaʻi i hana ʻia e nā lāʻau chemotherapy maʻi maʻi. Nui nā lāʻau chemotherapy e hiki ke hōʻoluʻolu loa iā ʻoe, a kōkua kēia lāʻau lapaʻau e pale i kēlā mau hōʻailona i hiki iā ʻoe ke nānā aku i kāu lapaʻau a me ka hoʻōla. He mea maikaʻi loa ia no ka pale ʻana i ka nausea koke (i loko o nā hola 24 mua) a me ka nausea lohi (hiki ke hana i nā lā ma hope o ka lāʻau).

Hoʻohana ʻia ka lāʻau lapaʻau no ka pale ʻana i ka nausea a me ka luaʻi ʻana ma hope o ke ʻoki ʻana, ʻoi loa ke komo ʻana o ka anesthesia maʻamau. Ua ʻoi aku ka maʻalahi o kekahi poʻe i ka nausea ma hope o ka hana ʻana, a hiki i ka palonosetron ke kōkua i ka hōʻoluʻolu o kou ola hou ʻana. E hoʻoholo kāu kauka inā he moho maikaʻi ʻoe no kēia lāʻau lapaʻau e pili ana i kāu hoʻolālā lapaʻau kikoʻī a me ka mōʻaukala olakino.

Pehea e hana ai ʻo Palonosetron?

Hana ʻo Palonosetron ma ka pale ʻana i nā mea hoʻokipa serotonin ma nā wahi nui ʻelua o kou kino: kou ʻōnaehana digestive a me kahi wahi kikoʻī i kou lolo i kapa ʻia ʻo ka chemoreceptor trigger zone. Ke komo nā lāʻau chemotherapy a i ʻole anesthesia i loko o kou ʻōnaehana, hiki iā lākou ke hoʻoulu i kou kino e hoʻokuʻu i nā mea nui o ka serotonin, e hōʻailona maʻamau i kou lolo e hoʻoulu i ka nausea a me ka luaʻi ʻana ma ke ʻano he pane pale.

Ua manaʻo ʻia kēia lāʻau lapaʻau he ikaika a maikaʻi hoʻi i hoʻohālikelike ʻia me nā lāʻau anti-nausea kahiko. He hopena lōʻihi kona, ʻo ia hoʻi, pono ʻoe i nā mea liʻiliʻi e noho palekana mai ka nausea. Hoʻomaka ka lāʻau lapaʻau e hana i loko o 30 mau minuke o ka lawelawe ʻana a hiki ke hāʻawi i ka pale ʻana no nā lā he nui, ma muli o kāu pane pilikino.

Pehea wau e lawe ai iā Palonosetron?

ʻAʻole ʻoe e

ʻAʻole pono ʻoe e hana i kekahi mea kūikawā e hoʻomākaukau ai no ka pahu, a ʻaʻole pono ʻoe e pale i ka ʻai a i ʻole nā mea inu ma mua. ʻO ka ʻoiaʻiʻo, ʻo ka loaʻa ʻana o kahi mea māmā i loko o kou ʻōpū e kōkua maoli nō ia iā ʻoe e ʻoluʻolu i ka holoʻokoʻa. E nānā kāu hui mālama ola iā ʻoe i ka wā a ma hope o ka pahu e hōʻoia ai e pane maikaʻi ana ʻoe i ka lāʻau.

Pehea ka lōʻihi e lawe ai au i ka Palonosetron?

Aia ka lōʻihi o ka mālama ʻana i ka palonosetron i kāu kūlana olakino kikoʻī. No nā maʻi chemotherapy, e loaʻa iā ʻoe hoʻokahi ma mua o kēlā me kēia kau lapaʻau i kāu pōʻai chemotherapy. ʻO ia hoʻi, e loaʻa ana iā ia i kēlā me kēia pule, i kēlā me kēia mau pule, a i ʻole ma kekahi papa hana i hoʻolālā ʻia e kāu oncologist no kāu mālama ʻana i ka maʻi kanesa.

No nā maʻi maʻi, e loaʻa iā ʻoe hoʻokahi ma mua o kāu kaʻina hana, a ua lawa kēlā maʻi hoʻokahi e pale ai i ka nausea ma hope o ka hana. Eia naʻe, inā he nui nā hana a i ʻole nā kaʻina hana lōʻihi, hiki i kāu kauka ke ʻōlelo i nā maʻi hou. E hana kāu hui mālama ola i kahi hoʻolālā pilikino e pili ana i kāu papa hana lapaʻau a me ka maikaʻi o kāu pane ʻana i ka lāʻau.

He aha nā hopena ʻaoʻao o Palonosetron?

ʻO ka hapa nui o nā kānaka e ʻae maikaʻi i ka palonosetron, akā e like me nā lāʻau lapaʻau, hiki iā ia ke hana i kekahi mau hopena ʻaoʻao. ʻO ka lono maikaʻi, ʻaʻole maʻamau nā hopena ʻaoʻao koʻikoʻi, a ʻoi aku ka maikaʻi o ka pale ʻana i ka nausea koʻikoʻi ma mua o nā pilikia.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike, me ka noʻonoʻo ʻana ʻaʻole loaʻa i nā kānaka he nui nā hopena ʻaoʻao:

• Poʻo (ʻo kēia ka hopena ʻaoʻao i hōʻike pinepine ʻia)
• Paʻa a i ʻole nā loli i nā neʻe ʻana o ka ʻōpū
• ʻO ka ʻūlū a i ʻole ka manaʻo māmā
• Luhi a i ʻole ka manaʻo luhi ma mua o ka maʻamau
• ʻEha māmā a i ʻole ka huhū ma ke kahua injection

He maʻamau ka maʻalahi a me ka manawa pōkole o kēia mau hopena ʻaoʻao. ʻIke kāu hui mālama ola pehea e mālama ai iā lākou inā loaʻa, no laila, mai kānalua e haʻi i kekahi ʻoluʻolu āu e manaʻo nei.

Aia kekahi mau hopena ʻaoʻao laha akā ʻoi aku ka koʻikoʻi e pono ai ka lāʻau lapaʻau koke. ʻOiai ʻaʻole pinepine kēia mau mea, he mea nui e ʻike iā lākou:

• Nā hopena maʻi maʻi koʻikoʻi (pilikia i ka hanu ʻana, pehu o ka maka a i ʻole ka ʻāʻī, ʻeha nui)
• Nā loli nui i ka puʻuwai (puʻuwai ʻole, ʻeha umauma)
• Paʻa paʻa nui ʻaʻole e hoʻomaikaʻi me ka lāʻau lapaʻau
• Nā loli ʻano ʻē a i ʻole ka huhū
• ʻO ka wili nui a i ʻole ka ʻūlū

Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona laha, e pane koke kāu hui lapaʻau iā lākou. E hoʻomanaʻo, aia ʻoe i kahi hoʻonohonoho lāʻau lapaʻau ke loaʻa nei kēia lāʻau, no laila, kokoke mau ke kōkua.

ʻO wai ka mea pono ʻole e lawe iā Palonosetron?

He palekana ʻo Palonosetron no ka hapa nui o nā kānaka, akā aia kekahi mau kūlana kahi e koho ai kāu kauka i kahi lāʻau ʻokoʻa. Pono ʻoe e haʻi i kāu hui mālama ola e pili ana i kāu mau maʻi a me nā lāʻau lapaʻau a pau ma mua o ka loaʻa ʻana o ka palonosetron e hōʻoia he koho kūpono ia nāu.

E mālama nui kāu kauka i ka kuhikuhi ʻana i ka palonosetron inā loaʻa iā ʻoe kekahi o kēia mau maʻi:

• ʻIke ʻia ka maʻi i ka palonosetron a i ʻole nā lāʻau like
• Nā pilikia o ka puʻuwai a i ʻole ka mōʻaukala ʻohana o kekahi mau maʻi puʻuwai
• Maʻi kīkī a i ʻole ate nui
• Nā kaulike ʻole o ka electrolyte (ʻoi aku ka haʻahaʻa o ka potassium a i ʻole ka magnesium)
• Hoʻohana ʻia i kēia manawa o kekahi mau lāʻau e pili ana i ka puʻuwai

Pono ka hāpai ʻana a me ka hānai ʻana i ka umauma i ka noʻonoʻo kūikawā, ʻoiai hiki ke hoʻohana ʻia ka palonosetron i kekahi manawa ke ʻoi aku ka maikaʻi ma mua o nā pilikia. E kūkākūkā kāu kauka i kēia mau mea me ʻoe inā pili lākou i kāu kūlana.

Nā inoa inoa Palonosetron

Loaʻa ʻo Palonosetron ma lalo o ka inoa inoa ʻo Aloxi, ʻo ia ka mana i hoʻohana nui ʻia ma nā halemai a me nā kikowaena lapaʻau. Hiki nō hoʻi iā ʻoe ke ʻike ʻia e kona inoa maʻamau, palonosetron hydrochloride, ma nā palapala lapaʻau a i ʻole ka ʻike kuhikuhi.

Hiki i kekahi mau keʻena ke hoʻohana i nā inoa inoa like ʻole a i ʻole nā mana maʻamau, akā loaʻa nā mea hana like a hana like. E haʻi aku kāu hui mālama ola iā ʻoe i ka mana kikoʻī āu e loaʻa nei, ʻoiai ʻaʻole pili ka inoa inoa i ka maikaʻi o ka lāʻau lapaʻau no ka pale ʻana i ka nausea.

Nā Koho ʻē aʻe o Palonosetron

Inā ʻaʻole kūpono ʻo palonosetron iā ʻoe, aia kekahi mau lāʻau anti-nausea maikaʻi ʻē aʻe e hiki ai i kāu kauka ke noʻonoʻo. Loaʻa i kēlā me kēia mea kona mau pono ponoʻī a hiki ke hana maikaʻi no nā poʻe like ʻole a i ʻole nā kūlana.

ʻO kekahi mau koho maʻamau e komo pū ana:

• Ondansetron (Zofran) - he mea kūʻē i ka mea loaʻa 5-HT3 ʻē aʻe e hana like ana akā he pōkole ka lōʻihi
• Granisetron (Kytril) - aia nō hoʻi i ka papa lāʻau lapaʻau like me ka manawa ʻokoʻa iki
• Dolasetron (Anzemet) - he koho ʻē aʻe i ka ʻohana like o nā lāʻau lapaʻau
• Metoclopramide (Reglan) - hana ma o kahi mīkini ʻokoʻa a hiki ke hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe
• Dexamethasone - he steroid hiki ke maikaʻi loa no ka nausea i hoʻokumu ʻia e ka chemotherapy

E koho kāu kauka i ke koho maikaʻi loa e pili ana i kāu kūlana olakino kikoʻī, nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, a pehea ʻoe i pane ai i nā lāʻau anti-nausea i ka wā i hala. I kekahi manawa, ʻoi aku ka maikaʻi o ka hui pū ʻana o nā lāʻau lapaʻau like ʻole ma mua o kekahi lāʻau hoʻokahi.

ʻOi aku ka maikaʻi o Palonosetron ma mua o Ondansetron?

He lāʻau lapaʻau maikaʻi ʻo Palonosetron a me Ondansetron no ka pale ʻana i ka nausea, akā he mau ʻokoʻa nui ko lākou e hiki ai ke kūpono kekahi no kou kūlana. ʻOi aku ka lōʻihi o ka Palonosetron i loko o kou kino, ʻo ia hoʻi, pono ʻoe i nā lāʻau liʻiliʻi a loaʻa ka pale lōʻihi mai ka nausea.

Makemake pinepine ʻia ʻo Palonosetron no ka chemotherapy emetogenic (nausea-causing) kiʻekiʻe no ka mea e hāʻawi ana i ka pale maikaʻi ʻana i ka nausea lohi e hiki ke hana 2-5 mau lā ma hope o ka mālama ʻana. Hana maikaʻi ʻo Ondansetron no ka nausea koke akā ʻaʻole paha e lōʻihi. Eia naʻe, ua hoʻohana ʻia ʻo ondansetron no nā makahiki he nui a he moʻolelo palekana nui, a me ka loaʻa ʻana o nā ʻano like ʻole me nā papa a me nā ʻāpana hoʻoheheʻe waha.

E noʻonoʻo kāu kauka i nā mea e like me ke ʻano o ka chemotherapy āu e loaʻa nei, kāu mōʻaukala olakino pilikino, a me kāu ʻinikua i ke koho ʻana ma waena o kēia mau lāʻau. He mea maikaʻi loa lāua ʻelua, a ʻo ke koho

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o ka Palonosetron?

Ma muli o ka hāʻawi ʻia ʻana o ka palonosetron e nā poʻe loea mālama ola i loko o kahi keʻena lapaʻau, ʻaʻole loa e loaʻa nā overdoses ulia pōpilikia. Hoʻohālikelike ʻia ka lāʻau lapaʻau a hāʻawi ʻia e like me nā protocols paʻa. Eia naʻe, inā hopohopo ʻoe ua loaʻa iā ʻoe ka nui, e haʻi koke i kāu kahu hānai a i ʻole kauka.

ʻO nā hōʻailona e hōʻike ana ua loaʻa iā ʻoe ka nui o ka lāʻau lapaʻau e pili ana i ka ʻūlū nui, ka puʻuwai puʻuwai ʻano ʻē, ka luhi nui, a i ʻole nā ​​hōʻailona e ʻoi aku ka maikaʻi ma mua o ka mea i manaʻo ʻia. Hoʻomaʻamaʻa ʻia kāu hui lapaʻau e ʻike a mālama i kēia mau kūlana me ka wikiwiki. E hoʻomanaʻo, aia ʻoe i kahi kaiapuni lapaʻau palekana kahi e loaʻa koke ai ke kōkua inā pono.

He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Palonosetron?

ʻAʻole pono ʻoe e hopohopo e pili ana i ka hala ʻana i kahi mahele o ka palonosetron no ka mea ua hāʻawi ʻia ma ke ʻano he ʻāpana o kāu mālama olakino i hoʻonohonoho ʻia. Inā hala ʻoe i kahi manawa chemotherapy kahi i manaʻo ʻia ai e loaʻa iā ʻoe ka palonosetron, e hoʻokaʻaʻike i kāu hui oncology e hoʻonohonoho hou i ka hiki wawe.

No nā maʻi maʻi, inā hoʻopaneʻe ʻia a hoʻonohonoho hou ʻia kāu kaʻina hana, e hoʻoponopono kāu hui lapaʻau i ka manawa o kāu mahele palonosetron. Mai ho'āʻo e hana i kahi mahele i hala iā ʻoe iho - e hana mau me kāu mau mea mālama ola e hoʻoholo i ke ala maikaʻi loa o ka hana. Hiki iā lākou ke ʻōlelo aku i nā lāʻau anti-nausea ʻē aʻe inā pono ʻoiai ʻoe e kali ana i kāu mālama i hoʻonohonoho hou ʻia.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Palonosetron?

E hooki ʻoe i ka loaʻa ʻana o ka palonosetron ke pono ʻole ʻoe i nā lāʻau lapaʻau e koi ai i ka pale anti-nausea. No nā maʻi chemotherapy, ʻo ia hoʻi ke hoʻopau ʻoe i kāu papa piha o ka mālama ʻana i ka maʻi kanesa. No nā maʻi maʻi, pono ʻoe i hoʻokahi mahele, no laila e hana maoli ka

E hōʻike aku kāu kauka iā ʻoe i ka wā e pono ʻole ai ka palonosetron ma ke ʻano he ʻāpana o kāu hoʻolālā lapaʻau. ʻAʻole like me kekahi mau lāʻau lapaʻau e pono e hoʻemi mālie ʻia, hiki ke hoʻōki koke ʻia ka palonosetron me ka ʻole o ke kaʻina hana tapering. Inā ke ʻike nei ʻoe i ka nausea ma hope o ka pau ʻana o kāu lapaʻau mua, hiki i kāu kauka ke ʻōlelo aku i nā lāʻau lapaʻau ʻē aʻe i kūpono no ka hoʻohana lōʻihi.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o ka Palonosetron?

Hiki i ka Palonosetron ke hoʻoulu i ka ʻūlū a i ʻole ka hiamoe i kekahi poʻe, no laila ʻaʻole ia i ʻōlelo ʻia e kalaiwa koke ma hope o ka loaʻa ʻana o ka lāʻau. Ma muli o ka loaʻa ʻana o ka palonosetron ma ke ʻano he ʻāpana o ka chemotherapy a i ʻole ka lapaʻau ʻana, e loaʻa paha iā ʻoe nā hoʻonohonoho kaʻa.

Manaʻo ka hapa nui o nā kikowaena lapaʻau e loaʻa i kekahi e hoʻokele iā ʻoe i ka home ma hope o ka loaʻa ʻana o ka chemotherapy a i ʻole ke ʻoki ʻana, me ka nānā ʻole i ka lāʻau anti-nausea i hoʻohana ʻia. E kali a hiki i kou manaʻo ʻana i ka makaʻala a paʻa loa ma mua o ke kalaiwa ʻana, hiki ke mau hola a i ʻole ka lā aʻe e pili ana i kāu mau lapaʻau ʻē aʻe. Ke kānalua, e noi i kāu hui mālama ola kino no ke alakaʻi kikoʻī e pili ana i kou kūlana pilikino a me ka pane ʻana i ka lāʻau.