He aha ka Pamidronate: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ʻo Pamidronate i hāʻawi ʻia ma o ka IV (intravenous) infusion e kōkua i ka hoʻoikaika ʻana i nā iwi a mālama i kekahi mau maʻi e pili ana i ka iwi. No ka hui o nā lāʻau lapaʻau i kapa ʻia ʻo bisphosphonates, e hana ana ma ka hoʻolohi ʻana i nā cell e wāwahi i ka ʻiʻo iwi.

Inā ua ʻōlelo kāu kauka iā pamidronate, e noʻonoʻo paha ʻoe i ka mea e manaʻo ai mai kēia lapaʻau. Hoʻohana pinepine ʻia kēia lāʻau lapaʻau i ka wā i lawa ʻole ai nā lapaʻau iwi ʻē aʻe, a i ʻole ke pono ʻoe i ka pale iwi ikaika ma muli o nā maʻi olakino.

He aha ka Pamidronate?

He lāʻau lapaʻau hoʻoikaika iwi ʻo Pamidronate hiki ke hāʻawi ʻia ma o ka vein i kou lima. ʻAʻole like me nā pila āu e lawe ai ma ka home, pono kēia lāʻau lapaʻau i kahi kipa i kahi keʻena lapaʻau a i ʻole ka haukapila no ka lawelawe ʻana.

E noʻonoʻo i kou mau iwi e kūkulu mau ana iā lākou iho. Wāwahi kekahi mau cell i ka iwi kahiko aʻo nā mea ʻē aʻe e kūkulu i ka iwi hou. Kōkua ʻo Pamidronate i ka hoʻololi ʻana i kēia kaulike i ke kūkulu ʻana i nā iwi ikaika a olakino ma ka hoʻolohi ʻana i ke kaʻina hana.

Noho ka lāʻau lapaʻau i loko o kāu ʻōnaehana no nā pule a i ʻole mau mahina ma hope o kēlā me kēia infusion, ʻo ia ke kumu ʻaʻole pono ʻoe iā ia i nā manawa he nui. Loaʻa ka hapa nui o nā kānaka i nā lapaʻau i kēlā me kēia mau pule a i ʻole mau mahina, ma muli o ko lākou kūlana.

No ke aha i hoʻohana ʻia ai ka Pamidronate?

Hoʻohana nui ʻia ʻo Pamidronate e mālama i nā pae calcium kiʻekiʻe i ke koko a me kekahi mau pilikia iwi e pili ana i ka maʻi maʻi. Hiki i kāu kauka ke kauoha iā ia inā loaʻa iā ʻoe ka hypercalcemia, kahi maʻi e lilo ai nā pae calcium i mea weliweli.

Hoʻohana pinepine ʻia ka lāʻau lapaʻau no ka poʻe me ka maʻi maʻi i laha i nā iwi, ʻoi aku hoʻi mai ka maʻi maʻi umauma, ka maʻi maʻi māmā, a i ʻole ka myeloma nui. I kēia mau hihia, kōkua ia i ka pale ʻana i nā haʻi iwi a hoʻemi i ka ʻeha iwi.

Eia kekahi, hiki i ka pamidronate ke mālama i ka maʻi o Paget, kahi maʻi e ulu nui a nāwaliwali nā iwi. Hoʻohana kekahi mau kauka i ia mea no ka osteoporosis koʻikoʻi ke hana ʻole nā ​​lāʻau lapaʻau ʻē aʻe.

Pehea e hana ai ʻo Pamidronate?

Ua manaʻo ʻia ʻo Pamidronate he lāʻau lapaʻau iwi ikaika e hana ana ma ka ʻimi ʻana i nā cell iwi kūikawā i kou mau iwi. Hoʻopili ia i ka ʻiʻo iwi a pale i ka hana o nā osteoclasts, ʻo ia nā cell e wāwahi ana i ka iwi.

Ke lohi kēia mau cell e wāwahi ana i ka iwi, loaʻa i kou mau iwi ka manawa hou e kūkulu hou a hoʻoikaika iā lākou iho. Kōkua kēia hana i ka hōʻemi ʻana i ka nui o ka calcium i hoʻokuʻu ʻia i loko o kou kahe koko a hoʻoikaika i kou mau iwi i ka haki.

ʻAʻole hana koke ka lāʻau lapaʻau. Hiki iā ʻoe ke hoʻomaka e ʻike i nā hoʻomaikaʻi ʻana i ka ʻeha iwi a i ʻole nā ​​pae calcium i loko o kekahi mau lā a i ʻole mau pule ma hope o kāu infusion mua. Hiki i nā hopena hoʻoikaika iwi piha ke lawe i kekahi mau mahina e hoʻomohala.

Pehea wau e lawe ai i ka Pamidronate?

Hāʻawi mau ʻia ʻo Pamidronate ma ke ʻano he infusion IV lohi i loko o kahi hoʻonohonoho lapaʻau, ʻaʻole loa ma ke ʻano he pill a i ʻole ka injection. Lawe maʻamau ke kaʻina hana i 2 a 4 mau hola, a pono ʻoe e noho ʻoluʻolu i kēia manawa.

Ma mua o kāu infusion, he mea nui e inu i ka wai nui ke ʻole e haʻi kāu kauka iā ʻoe. Kōkua ka hydration maikaʻi i ka pale ʻana i kou mau puʻupaʻa a hoʻemi i ka pilikia o nā hopena ʻaoʻao. Hiki iā ʻoe ke ʻai maʻamau ma mua a ma hope o ka lāʻau.

I ka wā o ka infusion, e kulu mālie ka lāʻau lapaʻau i loko o kou vein ma kahi paipu liʻiliʻi. E nānā pono ke kahu iā ʻoe a hiki ke nānā i kou koko a me ka mahana i kēlā me kēia manawa. Hiki iā ʻoe ke heluhelu, hoʻohana i kāu kelepona, a i ʻole e hoʻomaha i ka wā o ka lāʻau.

Ma hope o ka infusion, hiki iā ʻoe ke hoʻi i kāu mau hana maʻamau i kēia manawa. Eia naʻe, manaʻo kekahi poʻe i ka luhi a i ʻole ka ʻike ʻana i nā hōʻailona e like me ka maʻi flu no hoʻokahi a ʻelua paha lā ma hope, ʻoi aku ma hope o ka lāʻau mua.

Pehea ka lōʻihi e lawe ai au i ka Pamidronate?

He ʻokoʻa ka lōʻihi o ka mālama ʻana me ka pamidronate ma muli o kou maʻi a me ka maikaʻi o kou pane ʻana i ka lāʻau. Pono kekahi poʻe i hoʻokahi a ʻelua paha infusions, aʻo nā mea ʻē aʻe e hoʻomau i ka mālama ʻana no nā mahina a i ʻole nā makahiki.

No nā pae calcium kiʻekiʻe, pono paha ʻoe i hoʻokahi infusion e hoʻihoʻi i kāu calcium i ka maʻamau. Eia naʻe, inā mau ke kūlana ma lalo, pono paha ʻoe i nā lāʻau hou i kēlā me kēia pule a i ʻole mahina.

Inā he pilikia iwi pili i ka maʻi ʻaʻai, e ʻōlelo paha kāu kauka i ka mālama ʻana i ka wā e kōkua ana a ke ʻae maikaʻi nei ʻoe. ʻO ka pahuhopu ka pale ʻana i nā pilikia iwi a mālama i kou maikaʻi o ke ola.

E nānā mau kāu kauka i kāu pane ma o nā hoʻokolohua koko a me nā scans iwi. E hoʻoponopono lākou i kāu papa hana lapaʻau ma muli o ke ʻano o ka pane ʻana o kou mau iwi a inā paha e ʻike nei ʻoe i nā hopena ʻaoʻao.

He aha nā hopena ʻaoʻao o Pamidronate?

E like me nā lāʻau lapaʻau a pau, hiki i ka pamidronate ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole ʻike nā mea a pau iā lākou. ʻO nā hopena ʻaoʻao maʻamau ka maʻamau a me ka manawa.

Nui ka poʻe i ʻike i nā hōʻailona e like me ka maʻi flu ma hope o kā lākou infusion mua, he hōʻailona maoli kēia e hana ana ka lāʻau. Eia nā hopena ʻaoʻao maʻamau e ʻike ai ʻoe:

• Ka wela a me ke anu, e hoʻomaka ana i loko o 24 mau hola ma hope o ka mālama ʻana
• ʻEha ʻiʻo a me ka ʻeha hui e like me ka loaʻa ʻana o ka flu
• ʻO ka luhi a i ʻole ka manaʻo e luhi ma mua o ka maʻamau no hoʻokahi a ʻelua paha lā
• ʻO ka nausea a i ʻole ka pilikia o ka ʻōpū
• ʻO ke poʻo e hiki ke mau no hoʻokahi a ʻelua paha lā
• ʻEha a i ʻole ka huhū ma ke kahua IV

Hoʻomaikaʻi maʻamau kēia mau hopena ʻaoʻao maʻamau i loko o 48 mau hola a ʻoi aku ka liʻiliʻi me nā lāʻau lapaʻau ma hope. Hiki i ka lawe ʻana i nā mea hōʻoluʻolu ʻeha e like me ka acetaminophen ke kōkua i ka mālama ʻana i ka hōʻoluʻolu.

Hiki ke hana ʻia nā hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi, a pono ʻoe e hoʻokaʻaʻike i kāu kauka inā ʻike ʻoe i kekahi o kēia mau mea:

• He ʻeha nui o ka iwi ā a i ʻole ka paʻakikī o ka wehe ʻana i kou waha
• He ʻeha hou a ʻokoʻa paha ma ka ʻūhā, ka pūhaka, a i ʻole ka ʻūhā
• Nā loli i kou ʻike a i ʻole ka ʻeha o ka maka
• Ka luaʻi mau, ka luaʻi ʻana, a i ʻole ka nalowale o ka ʻai
• He luhi nui ʻaʻole i hoʻomaikaʻi ma hope o kekahi mau lā
• Nā hōʻailona o nā pae calcium haʻahaʻa e like me nā ʻūlū ʻiʻo a i ʻole ke kani

ʻO nā hopena ʻaoʻao laha ʻole akā koʻikoʻi e pili ana i ka osteonecrosis o ka iwi ā (ka make ʻana o ka iwi i loko o ka iwi ā) a me nā haʻi iwi ʻūhā ʻokoʻa. ʻAʻole maʻamau kēia mau pilikia akā he mea nui e nānā, ʻoi aku hoʻi me ka hoʻohana ʻana i ka wā lōʻihi.

ʻO wai ka mea pono ʻole e lawe iā Pamidronate?

ʻAʻole kūpono ʻo Pamidronate no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. ʻAʻole pono ʻoe e loaʻa i kēia lāʻau lapaʻau inā loaʻa iā ʻoe ka maʻi kīkī koʻikoʻi a i ʻole he maʻi maʻi i nā bisphosphonates.

ʻAʻole pono nā wāhine hāpai a i ʻole nā wāhine e hānai ana i ka waiū e hoʻohana i ka pamidronate, no ka mea, hiki iā ia ke hōʻeha i ka pēpē e ulu ana. Hiki ke noho ka lāʻau lapaʻau i loko o kou mau iwi no nā makahiki, no laila pono nā wāhine e hiki ke hāpai e kūkākūkā pono i kēia me kā lākou kauka.

Pono paha ka poʻe me kekahi mau pilikia niho a i ʻole ka poʻe e hoʻolālā ana i nā kaʻina hana niho e hoʻopaneʻe i ka lāʻau. Hiki i kāu kauka ke ʻōlelo aku e ʻike i ka dentist ma mua o ka hoʻomaka ʻana i ka pamidronate, ʻoiai inā pono ʻoe i nā unuhi niho a i ʻole ke ʻoki waha.

Inā he haʻahaʻa kou pae calcium, nā pilikia o ka puʻuwai, a i ʻole e lawe ana i kekahi mau lāʻau lapaʻau, pono kāu kauka e nānā pono iā ʻoe a i ʻole e hoʻoponopono i kāu hoʻolālā lapaʻau.

Nā inoa inoa Pamidronate

Loaʻa ʻo Pamidronate ma lalo o ka inoa inoa Aredia ma ʻAmelika Hui Pū ʻIa. Hiki nō hoʻi iā ʻoe ke ʻike iā ia e pili ana i kona inoa generic, pamidronate disodium.

Hana ʻia ka lāʻau lapaʻau e nā hui lāʻau lapaʻau he nui, akā like ka mea hana a me nā hopena me ka nānā ʻole i ka brand. E hoʻoholo kāu hale kūʻai lāʻau lapaʻau a i ʻole ke keʻena lapaʻau i ka mana āu e loaʻa ai.

Hiki i kekahi mau hoʻolālā ʻinikua ke makemake i kekahi mau mea hana, akā ʻaʻole pono kēia e hoʻopilikia i ka maikaʻi o kāu lapaʻau. ʻO ka mea nui, ke loaʻa nei iā ʻoe ka mahele kūpono o ka pamidronate no kou maʻi.

Nā Koho ʻē aʻe no Pamidronate

Nui nā lāʻau lapaʻau ʻē aʻe e hiki ke mālama i nā maʻi iwi like, akā e koho kāu kauka i ke koho maikaʻi loa e pili ana i kāu kūlana kikoʻī. Hiki ke hoʻohana ʻia nā bisphosphonates ʻē aʻe e like me ka waikawa zoledronic (Zometa) ma kahi o ka pamidronate.

No ka osteoporosis, hiki i nā bisphosphonates waha e like me alendronate (Fosamax) a i ʻole risedronate (Actonel) ke lilo i mau koho inā hiki iā ʻoe ke ʻae i nā pila. Lawe ʻia kēia mau mea ma ka waha ma mua o ka IV.

Hana nā lāʻau lapaʻau hou e like me denosumab (Prolia) i nā mea ʻokoʻa ma mua o nā bisphosphonates a hiki ke kūpono no kekahi poʻe i hiki ʻole ke lawe i ka pamidronate. Hiki nō hoʻi ke noʻonoʻo ʻia nā lāʻau lapaʻau hormone a i ʻole nā lāʻau lapaʻau e kūkulu iwi.

E noʻonoʻo kāu kauka i nā mea e like me kāu hana kīkī, nā lāʻau lapaʻau ʻē aʻe, a me nā makemake pilikino i ke koho ʻana i ka lapaʻau maikaʻi loa no kou olakino iwi.

Ua ʻoi aku ka maikaʻi o Pamidronate ma mua o ka Zoledronic Acid?

He mau bisphosphonates maikaʻi ʻo Pamidronate a me ka waikawa zoledronic, akā he mau ʻokoʻa ko lākou e hiki ai i kekahi ke kūpono iā ʻoe ma mua o kekahi. Manaʻo ʻia ka waikawa zoledronic he ʻoi aku ka ikaika a hāʻawi ʻia i ka liʻiliʻi.

Lawe nā infusions Pamidronate i 2 a 4 mau hola, ʻoiai hiki ke hāʻawi ʻia ka waikawa zoledronic ma luna o 15 a 30 mau minuke. Hiki i kēia ke maʻalahi ka waikawa zoledronic no kekahi poʻe, ʻoiai he mau lapaʻau maikaʻi nā mea ʻelua.

ʻO ke koho ma waena o kēia mau lāʻau lapaʻau e hilinaʻi pinepine ʻia i kāu maʻi kikoʻī, ka hana kīkī, a me ka maikaʻi o kou ʻae ʻana i kēlā me kēia lapaʻau. ʻOi aku ka maikaʻi o kekahi poʻe me kekahi lāʻau lapaʻau ma mua o kekahi ma ke ʻano o nā hopena ʻaoʻao.

E noʻonoʻo kāu kauka i kāu mau kūlana pilikino, me nā maʻi olakino ʻē aʻe a me nā lāʻau lapaʻau, i ka wā e hoʻoholo ai i ka bisphosphonate maikaʻi loa no ʻoe.

Nīnau pinepine ʻia e pili ana iā Pamidronate

He palekana anei ʻo Pamidronate no ka poʻe me ka maʻi kīkī?

Pono e noʻonoʻo pono ʻia ʻo Pamidronate i ka poʻe me nā pilikia kīkī. Hoʻoponopono ʻia ka lāʻau lapaʻau ma o kou mau kīkī, no laila hiki i ka hana kīkī i hōʻemi ʻia ke hoʻonui i ka pilikia o nā hopena ʻaoʻao.

E nānā kāu kauka i kāu hana kīkī me nā hoʻokolohua koko ma mua o kēlā me kēia lapaʻau a hiki ke hoʻoponopono i kāu mahele a i ʻole ka wikiwiki o ka hoʻokomo ʻana inā pono. ʻAʻole hiki i ka poʻe me ka maʻi kīkī koʻikoʻi ke loaʻa iā pamidronate me ka palekana.

Inā he mau pilikia kīkī maʻalahi a kūpono paha kāu, hiki i kāu kauka ke hāʻawi iā ʻoe i kahi mahele haʻahaʻa a i ʻole e hoʻolōʻihi i ka manawa hoʻokomo e hōʻemi i ke koʻikoʻi ma kāu mau kīkī. He mea nui ka noho ʻana i ka wai ma mua a ma hope o ka lapaʻau.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Pamidronate?

No ka mea, hāʻawi ʻia ʻo pamidronate i kahi hoʻonohonoho olakino i mālama ʻia, he mea maʻamau loa nā overdoses. Eia naʻe, inā hopohopo ʻoe e pili ana i ka loaʻa ʻana o ka nui o ka lāʻau lapaʻau, e haʻi koke i kāu hui mālama ola.

ʻO nā hōʻailona o ka loaʻa ʻana o ka nui o ka pamidronate e pili ana i nā hōʻailona e like me ka maʻi flu, nā hāʻule nui i nā pae calcium, a i ʻole nā ​​pilikia kīkī. E nānā pono nā limahana lapaʻau iā ʻoe a hiki ke hāʻawi i ka mālama kākoʻo inā pono.

ʻO ka nūhou maikaʻi, ʻaʻole maʻamau nā overdoses pamidronate no ka mea ua helu ʻia ka lāʻau lapaʻau a mālama ʻia e nā poʻe loea i hoʻomaʻamaʻa ʻia. E nānā pālua kāu hui lapaʻau i ka dosing ma mua o ka hoʻomaka ʻana i kāu hoʻokomo ʻana.

He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Pamidronate?

Inā hala ʻoe i kahi hoʻokomo pamidronate i hoʻonohonoho ʻia, e kelepona i ke keʻena o kāu kauka i ka hiki wawe e hoʻonohonoho hou. Mai ho'āʻo e hana i kahi mahele i hala ma ka loaʻa ʻana o ka lāʻau lapaʻau hou ma hope.

ʻO ka hala ʻana i hoʻokahi lapaʻau ʻaʻole ia e hoʻopilikia koke, akā he mea nui e mālama i kāu papa hana lapaʻau no nā hopena maikaʻi loa. Hiki i kāu kauka ke hoʻoponopono i kāu manawa mahele e hiki mai ana ma muli o ka lōʻihi o ka hala ʻana mai kāu hoʻokomo hope loa.

Inā ua hala ʻoe i nā lāʻau lapaʻau he nui, makemake paha kāu kauka e nānā i nā pae calcium o kou koko a i ʻole nā mea hōʻailona iwi ma mua o ka hoʻomau ʻana i ka lāʻau lapaʻau. E kōkua lākou iā ʻoe e hoʻi i ke ala me kāu hoʻolālā lapaʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Pamidronate?

Aia ka hoʻoholo e hooki i ka pamidronate i kou maʻi kumu a me ka maikaʻi o kou pane ʻana i ka lāʻau lapaʻau. Mai hooki i ka lāʻau lapaʻau me ka kūkākūkā ʻole ʻana me kāu kauka.

No nā pae calcium kiʻekiʻe, hiki iā ʻoe ke hooki i ka wā e hoʻi ai kāu calcium i ka maʻamau a paʻa. Eia naʻe, inā mau ke kumu kumu, pono paha ʻoe i ka lāʻau lapaʻau e pale ai i ka piʻi hou ʻana o nā pae calcium.

ʻO ka poʻe me nā pilikia iwi e pili ana i ka maʻi maʻi e hoʻomau pinepine i ka lāʻau lapaʻau inā e kōkua ana a ke ʻae nei lākou iā ia. E loiloi mau kāu kauka inā e hoʻomau nā pōmaikaʻi i ka lanakila ʻana i nā pilikia a i ʻole nā hopena ʻaoʻao.

Hiki iaʻu ke lawe i nā lāʻau lapaʻau ʻē aʻe i ka wā e loaʻa ana iā Pamidronate?

Hiki ke lawe palekana ʻia ka hapa nui o nā lāʻau lapaʻau me ka pamidronate, akā he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā huaora āu e lawe nei. Hiki i kekahi mau lāʻau lapaʻau ke launa pū me ka pamidronate a i ʻole e hoʻopilikia i kāu lāʻau lapaʻau.

Pono e lawe ʻia nā mea hoʻohui calcium a me nā antacids i nā manawa like ʻole ma mua o kāu pamidronate infusion e pale ai i ka hoʻopilikia ʻana. Hiki i kāu kauka ke ʻōlelo i ka manawa kikoʻī no kēia mau mea hoʻohui.

Pono paha nā mea hoʻokahe koko, kekahi mau lāʻau antibiotic, a me kekahi mau lāʻau lapaʻau maʻi maʻi i ka nānā ʻana i ka wā e hoʻohana ʻia me ka pamidronate. E hoʻonohonoho kāu hui mālama ola i kāu mau lāʻau lapaʻau e hōʻoia i ka hana palekana.