He aha ʻo Pegfilgrastim-pbbk: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Pegfilgrastim-pbbk he lāʻau biosimilar e kōkua ana i kou kino e hana i nā keʻokeʻo keʻokeʻo e hakakā ana i ka maʻi. Ua hoʻolālā ʻia no nā kānaka e loaʻa ana i ka lāʻau chemotherapy nona nā ʻōnaehana pale e pono ai ke kākoʻo hou e noho ikaika a olakino.

No ka hui o nā mea i kapa ʻia he colony-stimulating factors kēia lāʻau, e hana ana e like me nā ʻelele maoli i loko o kou kino. Ke nāwaliwali nā lāʻau lapaʻau maʻi maʻi i kou ʻōnaehana pale, komo ʻo pegfilgrastim-pbbk e kōkua i ka hoʻihoʻi ʻana i nā pale kūlohelohe o kou kino i ka maʻi.

He aha ʻo Pegfilgrastim-pbbk?

ʻO Pegfilgrastim-pbbk he mana biosimilar o ka lāʻau pegfilgrastim kumu. ʻO ka biosimilar ke ʻano e hana kokoke like me ka lāʻau kumu akā hana ʻia e kahi mea hana ʻē aʻe, pinepine ma ke kumu kūʻai haʻahaʻa me ka mālama ʻana i ka palekana a me ka pono.

ʻO ka lāʻau lapaʻau he mana synthetic o kahi protein e hana maoli ai kou kino i kapa ʻia ʻo granulocyte colony-stimulating factor (G-CSF). Hōʻike kēia protein i kou iwi iwi e hana i nā neutrophils hou aku, ʻo ia ke ʻano maʻamau o ke keʻokeʻo keʻokeʻo e hakakā ana i nā maʻi bacteria.

ʻO ka ʻāpana

Ua kauoha ʻia ka lāʻau lapaʻau no nā maʻi me nā maʻi maʻi non-myeloid e loaʻa ana i nā ʻōnaehana chemotherapy i loaʻa ka pilikia nui o ka hoʻoulu ʻana i ka neutropenia. ʻO ka Neutropenia kahi maʻi kahi e hāʻule ai kāu helu neutrophil i kahi haʻahaʻa weliweli, maʻamau ma lalo o 1,000 mau keena no ka microliter o ke koko.

Hiki i kāu kauka ke ʻōlelo aku i kēia lāʻau lapaʻau inā ua loaʻa mua iā ʻoe ka neutropenia koʻikoʻi a i ʻole nā maʻi koʻikoʻi i ka wā o nā pōʻai chemotherapy. He mea nui ia no nā maʻi e loaʻa ana i nā ʻōnaehana chemotherapy ikaika kahi e mālama ai i nā papa hana lapaʻau he mea nui no nā hopena maʻi maikaʻi loa.

I kekahi mau hihia, hiki i nā kauka ke kauoha i ka pegfilgrastim-pbbk no nā maʻi e loaʻa ana i nā transplants iwi iwi a i ʻole nā poʻe me kekahi mau maʻi koko, ʻoiai ʻaʻole maʻamau kēia mau hoʻohana a pono e mālama pono i ka lāʻau lapaʻau.

Pehea e hana ai ʻo Pegfilgrastim-pbbk?

Hana ʻo Pegfilgrastim-pbbk ma ka hoʻohālike ʻana i kahi protein maoli i loko o kou kino e hoʻoulu ai i ka iwi iwi e hana i nā keʻokeʻo keʻokeʻo. E noʻonoʻo iā ia e like me ka hoʻouna ʻana i kahi hōʻailona ikaika i ka hale hana keʻokeʻo keʻokeʻo o kou iwi iwi e hoʻonui i ka hana ke pono ʻoe.

Hoʻopili pono ka lāʻau lapaʻau i nā neutrophils, ʻo ia ka laina mua o kou kino e pale aku i nā maʻi bacteria. Ke loaʻa iā ʻoe ka chemotherapy, luku pinepine ʻia kēia mau keena me nā keena maʻi maʻi, e waiho ana iā ʻoe i ka manawa pōkole.

Ua manaʻo ʻia he lāʻau lapaʻau ikaika i ka wā e pili ana i kāna hopena olaola. ʻAʻole ia e hāʻawi wale i kahi hoʻoikaika mālie i kāu ʻōnaehana pale akā e wikiwiki ana i ka hana a me ka oʻo ʻana o nā keʻokeʻo keʻokeʻo i loko o kou iwi iwi.

ʻO ka ʻāpana

Hāʻawi ʻia ʻo Pegfilgrastim-pbbk ma ke ʻano he hoʻokahi injection ma lalo o ka ʻili (subcutaneous) hoʻokahi manawa no ke kaʻina chemotherapy. E hāʻawi maʻamau kāu mea mālama ola i kēia injection ma kahi hoʻonohonoho lapaʻau, akā hiki i kekahi poʻe maʻi ke aʻo e hāʻawi iā lākou iho i ka injection ma ka home.

Hāʻawi ʻia ka injection maʻamau 24 a 72 mau hola ma hope o ka pau ʻana o kāu lapaʻau chemotherapy, akā ʻaʻole i loko o 14 mau lā ma mua o kāu kaʻina chemotherapy e hiki mai ana. He mea nui kēia manawa no ka mea pono ka lāʻau lapaʻau e hana i ka wā e haʻahaʻa ai kāu helu keʻokeʻo koko.

ʻAʻole pono ʻoe e lawe i kēia lāʻau lapaʻau me ka meaʻai a i ʻole ka wai no ka mea he injection ia. Eia naʻe, hiki i ka noho ʻana i ka wai maikaʻi a me ka mālama ʻana i ka meaʻai maikaʻi ke kōkua i ke kākoʻo ʻana i kāu hoʻōla holoʻokoʻa a me ka hana ʻana o ka ʻōnaehana pale i ka wā o ka mālama ʻana.

Inā ʻoe e hāʻawi ana iā ʻoe iho i ka injection ma ka home, e hāʻawi kāu hui mālama ola i nā ʻōlelo kikoʻī e pili ana i ka ʻenehana injection kūpono, ka hoʻololi ʻana i ka pūnaewele, a me ka hoʻolei palekana ʻana i nā nila. ʻO nā wahi injection maʻamau e pili ana i ka lima luna, ka ʻūhā, a i ʻole ka ʻōpū, a pono ʻoe e hoʻololi i nā wahi e pale ai i ka huhū o ka ʻili.

Pehea ka lōʻihi e pono ai au e lawe iā Pegfilgrastim-pbbk?

E loaʻa iā ʻoe ka pegfilgrastim-pbbk no ka lōʻihi e loaʻa ana iā ʻoe nā pōʻai chemotherapy e hoʻokau iā ʻoe i ka pilikia no ka neutropenia. Hiki ke lōʻihi mai kekahi mau mahina a ʻoi aku paha ma mua o hoʻokahi makahiki, ma muli o kāu hoʻolālā lapaʻau maʻi maʻi.

Hāʻawi kēlā me kēia injection i ka pale no hoʻokahi pōʻai chemotherapy piha. E nānā kāu kauka i kāu helu keʻokeʻo koko maʻamau ma o nā hoʻokolohua koko e hōʻoia i ka hana pono ʻana o ka lāʻau lapaʻau a e hoʻoholo inā pono ʻoe e hoʻomau i ka mālama ʻana.

Aia ka lōʻihi o ka mālama ʻana i nā mea he nui, me ke ʻano o kāu maʻi maʻi, ka ikaika o kāu regimen chemotherapy, a me ke ʻano o kou kino e pane ai i ka lapaʻau maʻi a me ka pegfilgrastim-pbbk. Pono paha kekahi poʻe maʻi i kēlā me kēia pōʻai, ʻoiai ʻo nā mea ʻē aʻe e pono ai no kekahi mau pōʻai pilikia.

E loiloi hou kāu hui mālama ola i kou pono no kēia lāʻau lapaʻau i kāu mālama ʻana i ka maʻi ʻaʻai. Inā paʻa mau kāu helu keʻokeʻo koko me ka ʻole o ia mea, a i ʻole inā hoʻololi kāu papa chemotherapy i kahi protocol haʻahaʻa-pilikia, hiki paha iā ʻoe ke hooki i nā injections.

He aha nā hopena ʻaoʻao o Pegfilgrastim-pbbk?

E like me nā lāʻau lapaʻau a pau, hiki i ka pegfilgrastim-pbbk ke hana i nā hopena ʻaoʻao, ʻoiai he nui ka poʻe e ʻae maikaʻi iā ia. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e mākaukau a ʻike i ka manawa e hoʻopili ai i kāu hui mālama ola.

ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a hiki ke mālama ʻia me ka mālama kūpono a me ka nānā ʻana. Eia nā hopena ʻaoʻao āu e ʻike ai:

• ʻEha iwi a me ka ʻiʻo: Hoʻopilikia kēia i kahi 30-40% o nā maʻi a manaʻo pinepine e like me ka ʻeha hohonu i kou mau iwi, ʻoi aku hoʻi i kou kua, nā pūhaka, a me nā wāwae. Hoʻomaka ka ʻeha maʻamau 1-3 mau lā ma hope o ka injection a hiki ke mau no kekahi mau lā.
• Nā hopena ma ka pūnaewele injection: Hiki iā ʻoe ke ʻike i ka ʻulaʻula, ka pehu, a i ʻole ka ʻeha maʻalahi kahi i hāʻawi ʻia ai ka injection. He manawa pōkole kēia mau hopena a hoʻoponopono i loko o kekahi mau lā.
• Luhi a me ka nāwaliwali: Manaʻo kekahi poʻe e luhi ma mua o ka maʻamau, hiki ke pili i ka lāʻau lapaʻau a me ka mālama ʻana i ka maʻi maʻi.
• ʻEha poʻo: He maʻalahi a maʻalahi kēia mau mea a pane pinepine i nā mea hōʻoluʻolu ʻeha i ʻae ʻia e kāu kauka.

ʻO nā hopena ʻaoʻao liʻiliʻi akā naʻe, ʻo ka nausea, ka ʻūlū, a me ke kuni maʻalahi. ʻAʻole pono kēia mau hōʻailona i ka hoʻopau ʻana i ka mālama ʻana akā pono e hōʻike ʻia i kāu hui mālama ola.

Loaʻa i kekahi poʻe maʻi ka mea i kapa ʻia ʻo "bone pain syndrome," hiki ke ʻoi aku ka ikaika ma mua o ka ʻeha iwi maʻamau. Hiki i kēia ke manaʻo e like me ka ʻeha nui a i ʻole ka ʻeha ʻana i kou mau iwi a me nā hono. ʻOiai ʻoluʻolu ʻole, hōʻike kēia hopena ʻaoʻao e hana ana ka lāʻau lapaʻau e hoʻoulu i ka hana iwi iwi.

Pono nā hopena ʻaoʻao koʻikoʻi akā kakaʻikahi i ka lāʻau lapaʻau koke. Pākuʻi ʻia kēia mau mea i nā hopena maʻi maʻi koʻikoʻi, nā pilikia hanu, ke kuni kiʻekiʻe mau, a i ʻole nā hōʻailona o ka hoʻonui ʻana o ka spleen e like me ka ʻeha o ka ʻōpū luna hema. Eia kekahi, aia kahi pilikia liʻiliʻi loa o ka maʻi pilikia hanu nui, ʻoi aku hoʻi i nā maʻi me nā maʻi māmā.

Hiki i kekahi poʻe maʻi ke hoʻomohala i kahi maʻi i kapa ʻia ʻo cutaneous vasculitis, e ʻike ʻia e like me ka ʻōpala a i ʻole nā ʻeha ʻili. ʻOiai ʻaʻole maʻamau, pono kēia i ka loiloi olakino e hoʻoholo inā e hoʻomau ka mālama ʻana.

ʻO wai ka mea ʻaʻole pono e lawe iā Pegfilgrastim-pbbk?

ʻAʻole kūpono ʻo Pegfilgrastim-pbbk no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana. ʻO kekahi mau maʻi a me nā kūlana e hana i kēia lāʻau lapaʻau kūpono ʻole a i ʻole ka pōʻino.

ʻAʻole pono ʻoe e loaʻa iā pegfilgrastim-pbbk inā he maʻi ʻoe i ka pegfilgrastim, filgrastim, a i ʻole kekahi ʻāpana o ka lāʻau lapaʻau. ʻO nā hopena maʻi maʻi koʻikoʻi i nā lāʻau lapaʻau like e kāpae pū i kāna hoʻohana.

Pono ka poʻe me kekahi mau maʻi maʻi koko i ka noʻonoʻo kūikawā. Inā loaʻa iā ʻoe ka leukemia myeloid acute, myelodysplastic syndrome, a i ʻole nā maʻi maʻi koko ʻē aʻe e pili ana i kou iwi iwi, hiki i kēia lāʻau lapaʻau ke hoʻonui i kou maʻi ma ka hoʻoulu ʻana i ka ulu ʻana o nā cell cancer.

ʻAʻole paha he mau moho maikaʻi nā maʻi me ka mōʻaukala o ka maʻi māmā koʻikoʻi a i ʻole nā pilikia hanu no kēia lāʻau lapaʻau. Aia ka piʻi ʻana o ka pilikia o ka hoʻomohala ʻana i ka maʻi pilikia hanu nui, ʻoi aku hoʻi i ka poʻe me nā maʻi māmā.

Inā he ʻāpana nui kou a i ʻole he moʻolelo o nā pilikia ʻāpana, pono kāu kauka e ana pono i nā pilikia. Hiki i ka lāʻau lapaʻau ke hoʻonui hou i ka ʻāpana, a hiki ke alakaʻi i nā pilikia koʻikoʻi.

Pono nā wāhine hāpai a me nā wāhine e hānai ana i ka waiū i ka noʻonoʻo kūikawā. ʻOiai ʻaʻole i hōʻike maopopo ka lāʻau lapaʻau i ka pōʻino i nā haʻawina hāpai, pono e hoʻohana wale ʻia ke ʻoi aku ka maikaʻi ma mua o nā pilikia. Inā ʻoe e hoʻolālā ana e hāpai a i ʻole e hānai ana i ka waiū, e kūkākūkā pono i kēia me kāu hui mālama ola.

Nā inoa inoa o Pegfilgrastim-pbbk

Loaʻa ʻo Pegfilgrastim-pbbk ma lalo o ka inoa inoa ʻo Ziextenzo ma ʻAmelika Hui Pū ʻIa. ʻO kēia ka inoa inoa mua e hālāwai ai ʻoe ke kauoha kāu kauka i kēia lāʻau lapaʻau biosimilar.

He mea nui e hoʻomaopopo he biosimilar kēia lāʻau lapaʻau i ka pegfilgrastim kumu, i kūʻai ʻia ma lalo o ka inoa inoa ʻo Neulasta. ʻOiai hana like nā lāʻau lapaʻau ʻelua, ua hana ʻia e nā hui like ʻole a he mau mea hana ʻole like ʻole paha.

Hiki i kāu ʻinikua a me ka loaʻa ʻana o ka lāʻau lapaʻau ke hoʻopili i ka inoa inoa a i ʻole ka biosimilar āu e loaʻa ai. ʻO ka mea maikaʻi, ua hala nā mana i ʻae ʻia a pau i ka hoʻāʻo ʻana e hōʻoia i ka palekana a me ka pono no ka mālama ʻana i ka neutropenia.

Nā koho ʻē aʻe o Pegfilgrastim-pbbk

Nui nā koho ʻē aʻe inā ʻaʻole kūpono ʻo pegfilgrastim-pbbk iā ʻoe a i ʻole e loaʻa iā ʻoe nā hopena ʻaoʻao nui. Hiki i kāu kauka ke kōkua i ka hoʻoholo ʻana i ke koho maikaʻi loa e pili ana i kāu kūlana a me nā pono olakino.

ʻO ka pegfilgrastim kumu (Neulasta) ke koho pololei loa, e hana ana ma ke ala like akā ua hana ʻia e kahi hui ʻē aʻe. Loaʻa nō hoʻi nā mana biosimilar ʻē aʻe o pegfilgrastim, me Fulphila a me Nyvepria.

ʻO Filgrastim (Neupogen) he koho pōkole e koi ana i nā injections i kēlā me kēia lā ma kahi o ka hoʻokahi manawa i kēlā me kēia pōʻai. ʻOiai ʻaʻole maʻalahi, ʻoi aku ka maikaʻi o ka hoʻomanawanui ʻana e kekahi poʻe maʻi a hiki ke hoʻololi i nā hoʻoponopono ʻana i ka dosage.

No nā maʻi i hiki ʻole ke hoʻomanawanui i kekahi o kēia mau lāʻau lapaʻau, hiki i kāu kauka ke noʻonoʻo i nā ala ʻē aʻe e like me ka hoʻemi ʻana i ka dosage o ka chemotherapy, nā papa hana lapaʻau i hoʻololi ʻia, a i ʻole nā antibiotics prophylactic e hōʻemi i ka pilikia o ka maʻi i nā manawa o ka helu haʻahaʻa o nā keʻena koko keʻokeʻo.

Ua ʻoi aku ka maikaʻi o Pegfilgrastim-pbbk ma mua o Neulasta?

Ua like ʻo Pegfilgrastim-pbbk a me Neulasta i ka palekana a me ka pono. Loaʻa i nā lāʻau lapaʻau ʻelua ka mea hana like a hana i nā ala like e pale ai i ka neutropenia i ka wā o ka mālama chemotherapy.

ʻO ka pōmaikaʻi nui o pegfilgrastim-pbbk ʻo ia ka mālama kālā. Ma ke ʻano he lāʻau lapaʻau biosimilar, ʻoi aku ka liʻiliʻi o ke kumukūʻai ma mua o ka Neulasta kumu i ka wā e hāʻawi ana i nā pono therapeutic like. Hiki i kēia ke maʻalahi i ka mālama ʻana a hoʻemi i nā kumukūʻai mālama ola.

Hiki i kekahi poʻe maʻi ke loaʻa nā ʻike like ʻole me nā hopena ʻaoʻao a i ʻole nā hopena o ka pūnaewele injection ma muli o nā ʻokoʻa liʻiliʻi i nā mea hana ʻole, akā he liʻiliʻi kēia mau ʻokoʻa. Loaʻa i nā lāʻau lapaʻau ʻelua ka papa hana dosing like a me nā koi nānā.

E hilinaʻi paha kāu koho ma waena o nā mea ʻelua i nā mea e like me ka uhi ʻinikua, ka loaʻa ʻana o ka lāʻau lapaʻau, a me ka makemake o kāu mea mālama ola. Nui nā kauka e ʻoluʻolu e hoʻololi ma waena o kēia mau lāʻau lapaʻau ma muli o nā manaʻo kūpono ma mua o nā ʻokoʻa lapaʻau.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Pegfilgrastim-pbbk

He palekana ʻo Pegfilgrastim-pbbk no ka poʻe maʻi maʻi diabetes?

He palekana maʻamau ʻo Pegfilgrastim-pbbk no ka poʻe me ka maʻi diabetes, akā pono paha e nānā pono ʻia nā pae kōpaʻa koko i ka wā e mālama ʻia ai. ʻAʻole pili pololei ka lāʻau lapaʻau i ke glucose koko, akā ʻo ke kaumaha o ka mālama ʻana i ka maʻi maʻi me nā hopena ʻaoʻao e like me ka luhi e pili ana i kāu mālama ʻana i ka maʻi diabetes.

Loaʻa kekahi poʻe maʻi i nā loli liʻiliʻi i ka ʻai a i ʻole nā pae ikehu e hiki ke pili ʻole i ka mālama ʻana i ke kōpaʻa koko. E hana pili me kāu oncologist a me ka hui mālama diabetes e hoʻoponopono i kāu mau lāʻau diabetes inā pono i ka wā e mālama ʻia ai ka maʻi maʻi.

He aha kaʻu e hana ai inā hoʻohana hewa au i ka nui o Pegfilgrastim-pbbk?

Inā loaʻa iā ʻoe ka nui o ka pegfilgrastim-pbbk, e hoʻokaʻaʻike koke i kāu mea mālama ola. ʻOiai he kakaikahi ka overdose no ka mea hāʻawi pinepine ʻia ka lāʻau lapaʻau e nā poʻe loea mālama ola, hiki i nā mea nui ke hoʻonui i ka pilikia o nā hopena ʻaoʻao, ʻoi aku ka ʻeha o ka iwi a me nā pilikia o ka helu koko.

Makemake paha kāu kauka e nānā pinepine i kāu mau helu koko a nānā i nā hōʻailona o nā pilikia. Mai hoʻāʻo e pale i ka overdose iā ʻoe iho, a e ʻimi koke i ka lāʻau lapaʻau no ka loiloi kūpono a me ka mālama.

He aha kaʻu e hana ai inā hala wau i kahi mahele o Pegfilgrastim-pbbk?

Inā hala ʻoe i kāu injection pegfilgrastim-pbbk i hoʻonohonoho ʻia, e hoʻokaʻaʻike i kāu mea mālama ola i ka hiki wawe e hoʻonohonoho hou. He mea nui ka manawa o kēia lāʻau lapaʻau no ka pale ʻana i ka neutropenia i ka wā o kāu pōʻai chemotherapy.

Ma muli o ka nui o ka manawa i hala a me kahi āu i loko o kāu pōʻai lapaʻau, hiki i kāu kauka ke hāʻawi iā ʻoe i ka injection a i ʻole e kali a hiki i kāu pōʻai chemotherapy e hiki mai ana. Mai pāpālua i nā mahele a i ʻole e hoʻāʻo e hopu iā ʻoe iho.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Pegfilgrastim-pbbk?

Hiki iā ʻoe ke hooki i ka lawe ʻana i ka pegfilgrastim-pbbk ke pau kāu lapaʻau chemotherapy a i ʻole ke hoʻoholo kāu kauka ʻaʻole pono ʻoe ia mea ma muli o kāu helu keʻokeʻo koko a me ka pilikia o ka maʻi. Hiki i kekahi poʻe maʻi ke hooki mua inā loaʻa iā lākou nā hopena ʻaoʻao nui a i ʻole inā hoʻololi kā lākou hoʻolālā lapaʻau.

E nānā mau kāu hui mālama ola i kāu helu koko a e hoʻoholo i kēia hoʻoholo ma muli o kāu pane pilikino i ka lapaʻau. Mai hooki i ka lāʻau lapaʻau ma kāu iho me ka ʻole e kūkākūkā i kāu kauka, no ka mea, hiki i kēia ke waiho iā ʻoe i ka pilikia i nā maʻi koʻikoʻi.

Hiki iaʻu ke hoʻoikaika kino i ka wā e lawe ana i ka Pegfilgrastim-pbbk?

He palekana ka hoʻoikaika kino māmā a me ka maʻalahi i ka wā e lawe ana i ka pegfilgrastim-pbbk, akā pono ʻoe e hoʻolohe i kou kino a pale i nā hana e hoʻonui ai i ka ʻeha o ka iwi a i ʻole ka luhi. Hoʻokumu pinepine ka lāʻau lapaʻau i ka ʻeha o ka iwi a me ka ʻiʻo e hiki ke hōʻoluʻolu ʻole i ka hoʻoikaika kino ikaika.

Hiki i nā hana mālie e like me ka hele wāwae, ke kikoo ʻana, a i ʻole ka yoga māmā ke kōkua maoli i ka mālama ʻana i ka ʻeha o ka iwi a hoʻomaikaʻi i ka maikaʻi holoʻokoʻa i ka wā o ka lapaʻau. Eia naʻe, e pale i nā haʻuki pili a i ʻole nā hana me ka pilikia kiʻekiʻe o ka ʻeha, no ka mea, ke hana ikaika nei kou kino e kūkulu hou i kāu ʻōnaehana pale a pono i ka ikehu no ka hoʻōla.