He aha ʻo Prasugrel: Nā Hoʻohana, Nā Ana, Nā ʻAoʻao ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau ʻo Prasugrel e kōkua ana i ka pale ʻana i nā koko koko weliweli mai ka hana ʻana i loko o kou mau aʻa. Hiki i kāu kauka ke kuhikuhi i kēia lāʻau lapaʻau inā ua loaʻa iā ʻoe ka puʻuwai a i ʻole ka ʻeha o ka umauma a pono ʻoe i kahi kaʻina hana e like me ka angioplasty e wehe i nā aʻa i ālaina ʻia. E noʻonoʻo iā prasugrel ma ke ʻano he mea kōkua o kou kino i ka mālama ʻana i ke kahe ʻana o ke koko ma nā moku o kou puʻuwai, e hōʻemi ana i ka pilikia o kekahi puʻuwai a i ʻole ka hahau.

He aha ʻo Prasugrel?

No ka hui ʻo Prasugrel o nā lāʻau lapaʻau i kapa ʻia he lāʻau antiplatelet, e hana ana ma ka pale ʻana i nā cell koko liʻiliʻi i kapa ʻia he platelets mai ka pili pū ʻana. Ke hui pū nā platelets, hiki iā lākou ke hana i nā koko koko weliweli e ālai i ke kahe koko i kou puʻuwai a i ʻole ka lolo. Ua hoʻolālā kūikawā ʻia kēia lāʻau lapaʻau no ka poʻe i loaʻa i ka maʻi coronary acute, he maʻi puʻuwai koʻikoʻi e pili ana i ka puʻuwai a me ka ʻeha o ka umauma paʻa.

E kuhikuhi maʻamau kāu kauka iā prasugrel me ka aspirin ma ke ʻano he ʻāpana o ka mea i kapa ʻia he dual antiplatelet therapy. Hāʻawi kēia hui i ka pale ikaika aku i nā koko koko ma mua o kekahi lāʻau lapaʻau wale nō. Ua manaʻo ʻia ʻo Prasugrel he mea lahilahi koko ikaika ma mua o kekahi mau koho ʻē aʻe, kahi e hana ai i mea maikaʻi loa akā pono nō hoʻi ka nānā pono ʻana.

No ke aha i hoʻohana ʻia ai ʻo Prasugrel?

Hoʻohana nui ʻia ʻo Prasugrel e pale i nā koko koko i ka poʻe me ka maʻi coronary acute e hele ana i kahi kaʻina hana i kapa ʻia he percutaneous coronary intervention (PCI). He lapaʻau ʻo PCI kahi e hoʻokomo ai nā kauka i kahi baluna liʻiliʻi a i ʻole stent e wehe i nā aʻa i ālaina ʻia i loko o kou puʻuwai. Kōkua ka lāʻau lapaʻau i ka mālama ʻana i kēia mau aʻa i wehe hou ʻia a pale i ka hana ʻana o nā koko koko hou.

Hiki i kāu kauka ke kuhikuhi iā prasugrel inā ua loaʻa iā ʻoe ka puʻuwai a i ʻole he angina paʻa ʻole, ʻo ia ka ʻeha umauma nui e kū mai ana ke loaʻa ʻole ka nui o ke koko i kou ʻiʻo puʻuwai. Ua manaʻo ʻia ka lāʻau lapaʻau no ka poʻe e hoʻolālā nei e loaʻa a i ʻole i loaʻa i ka angioplasty me ka hoʻokomo ʻana i ka stent. Kōkua kēia hoʻohana i manaʻo ʻia e hōʻoia e loaʻa iā ʻoe ka pōmaikaʻi nui loa me ka hōʻemi ʻana i nā pilikia pono ʻole.

Pehea e Hana ai ʻo Prasugrel?

Hana ʻo Prasugrel ma ka pale mau ʻana i nā mea hoʻokipa kikoʻī ma kāu platelets i kapa ʻia ʻo P2Y12 receptors. Ke ālai ʻia kēia mau mea hoʻokipa, ʻaʻole hiki i kāu platelets ke loaʻa nā hōʻailona kemika e haʻi maʻamau iā lākou e pili pū a hana i nā clots. He mau ka hana ālai no ke ola holoʻokoʻa o kāu platelets, ʻo ia hoʻi ma kahi o 7 a 10 mau lā.

Ua manaʻo ʻia kēia lāʻau lapaʻau he mea ikaika loa i hoʻohālikelike ʻia me nā mea lahilahi koko ʻē aʻe e like me clopidogrel. ʻOiai ʻo kēia ikaika e hana maikaʻi loa i ka pale ʻana i nā clots, ʻo ia hoʻi e lōʻihi ka manawa o kou koko e clot inā ʻoe e ʻoki a ʻeha paha. Pono e hoʻāla ʻia ka lāʻau lapaʻau e kou ate ma mua o ka hana ʻana, e hana maʻamau i loko o kekahi mau hola o ka lawe ʻana i kāu mahele mua.

Pehea wau e lawe ai iā Prasugrel?

E lawe iā prasugrel e like me ke kauoha a kāu kauka, maʻamau i hoʻokahi manawa i ka lā me ka ʻole o ka meaʻai. Hiki iā ʻoe ke lawe me ka wai, ka waiū, a i ʻole ka wai, i nā mea āu e ʻoluʻolu ai. Hana like ka lāʻau lapaʻau inā lawe ʻoe ma ka ʻōpū ʻole a i ʻole me nā meaʻai, no laila hiki iā ʻoe ke koho i ka manawa e kūpono i kāu hana maʻamau.

Manaʻo ka hapa nui o ka poʻe he mea kōkua ke lawe iā prasugrel i ka manawa like i kēlā me kēia lā e mālama i nā pae mau i loko o ko lākou koko. Inā ʻoe e lawe pū ana i ka aspirin, hiki iā ʻoe ke lawe i nā lāʻau ʻelua pū a i ʻole kaʻawale, ʻo ka mea a kāu kauka e ʻōlelo ai. Mai ʻoki, nau, a haki paha i nā papa, no ka mea, hiki i kēia ke hoʻopilikia i ke ʻano o ka lawe ʻana i ka lāʻau i loko o kāu ʻōnaehana.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi mahele hoʻouka, ʻo ia hoʻi ka nui kiʻekiʻe i kāu lā mua e hana wikiwiki ai ka lāʻau. Ma hope o kēlā, e lawe ʻoe i kahi mahele mālama haʻahaʻa i kēlā me kēia lā. ʻO ka mahele mālama maʻamau he 10 mg i hoʻokahi manawa i ka lā, akā hiki i kāu kauka ke kuhikuhi i 5 mg inā ʻoe ma luna o 75 mau makahiki a i ʻole ke kaumaha ma lalo o 132 paona.

Pehea ka lōʻihi e lawe ai au i ka Prasugrel?

Hoʻololi ka lōʻihi o ka mālama ʻana i ka prasugrel ma muli o kou kūlana kikoʻī a me nā mea pilikia. Lawe ka hapa nui o nā kānaka iā ia no ka liʻiliʻi o 12 mau mahina ma hope o kā lākou hana puʻuwai, no ka mea, hāʻawi kēia manawa i ka pale nui loa i nā clots weliweli. E loiloi kāu kauka i nā pōmaikaʻi o ka pale ʻana i ka clot e hoʻomau ʻia ana i ka pilikia o ke kahe koko e hoʻoholo ai i ka lōʻihi kūpono no ʻoe.

Pono paha kekahi poʻe e lawe i ka prasugrel no ka lōʻihi ma mua o hoʻokahi makahiki, ʻoiai inā he pilikia nui ko lākou i nā pilikia puʻuwai e hiki mai ana. Hiki i nā mea ʻē aʻe ke hooki koke inā loaʻa iā lākou nā pilikia kahe koko a i ʻole pono i ke ʻoki. E loiloi mau kāu kauka i kāu holomua a hoʻoponopono i kāu hoʻolālā lapaʻau e like me ka mea e pono ai.

Mai hooki i ka lawe ʻana i ka prasugrel me ka ʻole e kamaʻilio mua me kāu kauka, ʻoiai inā maikaʻi ʻoe. ʻO ka hooki ʻana i ka wikiwiki hiki ke hoʻonui i kou pilikia o nā clots koko a hiki ke alakaʻi i ka puʻuwai a i ʻole ka hahau. Inā pono ʻoe e hooki i ka lāʻau no kekahi kumu, e hāʻawi kāu kauka i nā ʻōlelo kikoʻī e pili ana i ka hana ʻana pēlā me ka palekana.

He aha nā hopena ʻaoʻao o Prasugrel?

E like me nā mea hoʻoheheʻe koko a pau, hiki i ka prasugrel ke hoʻonui i kou pilikia o ke kahe koko, ʻo ia ka hopena ʻaoʻao nui e nānā ai. Hiki ke loli kēia mai ke kahe koko liʻiliʻi e like me ka ihu a i ʻole ka maʻalahi o ka ʻeha i ke kahe koko kūloko koʻikoʻi. ʻO ka hoʻomaopopo ʻana i kēia mau hopena hiki ke kōkua iā ʻoe e ʻike i ka wā e ʻimi ai i ka lāʻau lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau e ʻike ai ka poʻe he nui:

• He maʻalahi ka ʻeha a i ʻole nā ʻeha e ʻike ʻia me ka ʻole o ka ʻeha
• He lōʻihi ka manawa e kū ai ka ihu ma mua o ka maʻamau
• Ke kahe ke koko o nā ʻāʻī i ka wā e palaki ai i nā niho
• Nā kiko ʻulaʻula a poni paha ma kou ʻili
• Nā ʻeha poʻo, ʻoi loa i nā pule mua
• Ka wili a i ʻole ka manaʻo māmā

He maʻalahi kēia mau hopena maʻamau a pinepine e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau. Eia naʻe, pono nō ʻoe e haʻi iā lākou i kāu kauka i kāu mau nānā maʻamau.

Pono nā hopena ʻaoʻao koʻikoʻi i ka mālama olakino koke a komo pū:

• Ke kahe nui ʻana o ke koko ʻaʻole e kū ma hope o 10 mau minuke o ke kaomi pololei
• Ke koko i loko o kou mimi a i ʻole ka ʻōpala, a i ʻole nā ʻōpala ʻeleʻele, tarry
• Ka luaʻi ʻana i ke koko a i ʻole nā mea e like me nā kumu kope
• ʻEha poʻo nui me ka huikau a i ʻole nā loli i ka ʻike
• ʻEha umauma a i ʻole ka pōkole o ka hanu
• Nāwaliwali a i ʻole ka ʻeha ma kekahi ʻaoʻao o kou kino

ʻAʻole maʻamau kēia mau hopena koʻikoʻi akā hiki ke hoʻoweliweli i ke ola. Inā ʻike ʻoe i kekahi o kēia mau hōʻailona, e kelepona iā 911 a i ʻole e ʻimi koke i ka mālama olakino pilikia.

ʻO nā hopena ʻaoʻao maʻamau akā koʻikoʻi e komo pū ana me kahi maʻi i kapa ʻia ʻo thrombotic thrombocytopenic purpura (TTP), e pili ana i kou koko a me nā ʻōpū. ʻO nā hōʻailona o TTP e komo pū ana me ke kuni, nāwaliwali, nā loli kala ʻili, huikau, a me ka hoʻemi ʻia o ka mimi. Pono kēia maʻi i ka mālama ʻana i ka haukapila koke akā hiki mai i ka liʻiliʻi ma mua o 1 i ka 100,000 poʻe e lawe ana i ka prasugrel.

ʻO wai ka mea pono ʻole e lawe i ka Prasugrel?

ʻAʻole kūpono ʻo Prasugrel no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. ʻAʻole kūpono paha nā kānaka me kekahi mau maʻi a i ʻole nā mea pilikia no kēia lāʻau lapaʻau ma muli o ka piʻi ʻana o nā pilikia o ke kahe ʻana a i ʻole ka emi ʻana o ka pono.

ʻAʻole pono ʻoe e lawe i ka prasugrel inā loaʻa iā ʻoe:

• Ke kahe ʻana o ke koko ma nā wahi a pau o kou kino
• He moʻolelo o ka hahau ʻana a i ʻole ka hoʻouka ʻana i ka ischemic transient (mini-stroke)
• Maʻi ate koʻikoʻi
• ʻIke ʻia nā maʻi āpau i ka prasugrel a i ʻole nā lāʻau lapaʻau like
• Hoʻolālā ʻia ke ʻoki ʻana i ka wā e hiki mai ana

Hoʻonui nui kēia mau kūlana i kou pilikia o nā pilikia koʻikoʻi, e hana ana i ka prasugrel i mea palekana ʻole iā ʻoe.

E hoʻohana kāu kauka i ka mālama keu inā ʻoe:

• Ma luna o 75 mau makahiki
• Kaumaha ma lalo o 132 paona
• He moʻolelo o nā maʻi kahe koko
• Lawe i nā lāʻau lapaʻau hoʻoheheʻe koko ʻē aʻe
• Loaʻa i ka maʻi kīkī
• Ua hoʻonohonoho ʻia no ke ʻoki ʻana a i ʻole nā kaʻina hana niho

ʻAʻole pono kēia mau mea e pale iā ʻoe mai ka lawe ʻana i ka prasugrel, akā pono paha lākou i nā hoʻoponopono dosage a i ʻole ka nānā pinepine ʻana e hōʻoia i kou palekana.

Nā inoa inoa o Prasugrel

Loaʻa pinepine ʻia ka Prasugrel ma lalo o ka inoa inoa Effient ma ʻAmelika Hui Pū ʻIa. ʻO kēia ka mana inoa mua i hoʻomohala ʻia e nā hui lāʻau lapaʻau i hana mua i ka lāʻau lapaʻau. Loaʻa ka Effient i nā papa 5 mg a me 10 mg a loaʻa ākea ma ka hapa nui o nā lāʻau lapaʻau.

Loaʻa pū kekahi nā mana generic o prasugrel a loaʻa i ka mea hana like me Effient. ʻOi aku ka liʻiliʻi o kēia mau koho generic a hana like me ka mana inoa. Hiki i kāu ʻinikua ke makemake i ka mana generic, hiki ke kōkua i ka hōʻemi ʻana i kāu mau kumukūʻai mai ka ʻeke.

Nā koho ʻē aʻe o Prasugrel

Inā ʻaʻole kūpono ka prasugrel iā ʻoe, hiki i kekahi mau lāʻau antiplatelet ʻē aʻe ke hāʻawi i ka pale like ʻana i nā clots koko. ʻO ka mea maʻamau ʻo clopidogrel (Plavix), e hana ana ma ke ʻano like akā ua manaʻo ʻia he emi ka mana ma mua o ka prasugrel. Hiki i kāu kauka ke koho i ka clopidogrel inā loaʻa iā ʻoe ka pilikia kahe koko kiʻekiʻe a i ʻole nā mea ʻē aʻe e hana ai i ka prasugrel i kūpono ʻole.

ʻO kekahi koho ʻē aʻe ʻo ticagrelor (Brilinta), hiki ke hoʻohuli ʻia a ʻaʻole pono e hoʻāla ʻia e kou ate e like me ka prasugrel. Lawe ʻia ʻo Ticagrelor ʻelua manawa i ka lā ma kahi o hoʻokahi manawa i ka lā a makemake ʻia i kekahi mau kūlana. Loaʻa i kēlā me kēia o kēia mau koho ʻē aʻe i kāna mau pōmaikaʻi a me nā pilikia, e wehewehe ʻia e kāu kauka e pili ana i kou kūlana.

No kekahi poʻe, lawa paha ka aspirin wale nō, ʻoiai no ka pale lōʻihi ma hope o ka hala ʻana o ka manawa pilikia mua. E hana pū kāu kauka me ʻoe e ʻimi i ka mea lahilahi koko e hāʻawi ana i ke kaulike maikaʻi loa o ka pale ʻana i ka clot a me ka pilikia o ke koko no kou mau kūlana pilikino.

Ua ʻoi aku ka maikaʻi o Prasugrel ma mua o Clopidogrel?

ʻOi aku ka maikaʻi o Prasugrel ma mua o clopidogrel i ka pale ʻana i nā clots koko, akā lawe pū kekahi i ka pilikia o ke koko. Ua hōʻike nā haʻawina e hōʻemi ana ʻo prasugrel i ka pilikia o ka puʻuwai, ka hahau, a me ka make cardiovascular ʻoi aku ka maikaʻi ma mua o clopidogrel i ka poʻe me ka maʻi coronary acute e hele ana i ka PCI. Eia naʻe, hele mai kēia hoʻonui ʻia me ka piʻi ʻana o ka pilikia o ke koko nui.

Aia ke koho ma waena o kēia mau lāʻau lapaʻau i kāu mau mea pilikia pilikino. Inā he pilikia nui kou i nā clots koko a me ka pilikia haʻahaʻa o ke koko, ʻo prasugrel paha ke koho maikaʻi loa. Inā he pilikia nui kou i ke koko a i ʻole ma luna o 75 mau makahiki, ʻoi aku ka palekana o clopidogrel iā ʻoe. E noʻonoʻo kāu kauka i kou makahiki, ke kaumaha, ka mōʻaukala olakino, a me nā mea ʻē aʻe e hoʻoholo ai i ka lāʻau lapaʻau kūpono.

ʻAʻole pane maikaʻi kekahi poʻe i ka clopidogrel ma muli o nā ʻano genetic e pili ana i ke ʻano o ka hana ʻana o ko lākou kino i ka lāʻau lapaʻau. He koho maikaʻi paha ʻo Prasugrel no kēia mau kānaka no ka mea ʻaʻole i hoʻopilikia ʻia e kēia mau ʻokoʻa genetic. Hiki i kāu kauka ke kauoha i ka hoʻāʻo genetic inā he hopohopo e pili ana i ka maikaʻi o kāu pane ʻana i ka clopidogrel.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Prasugrel

He palekana ʻo Prasugrel no ka poʻe me ka maʻi diabetes?

ʻAe, palekana maʻamau ʻo prasugrel no ka poʻe me ka maʻi diabetes a he mea maikaʻi paha ia no kēia pūʻulu. ʻO ka poʻe me ka maʻi diabetes pinepine ka pilikia nui o nā koko koko a me nā pilikia o ka naʻau, e hana ana i ka lāʻau antiplatelet maikaʻi loa. Ua hōʻike nā haʻawina e hiki ke ʻoi aku ka maikaʻi o prasugrel ma mua o nā mea lahilahi koko ʻē aʻe i ka poʻe me ka maʻi diabetes.

Eia naʻe, inā he maʻi diabetes kāu, e nānā pono kāu kauka iā ʻoe no ka mea hiki i ka maʻi diabetes ke hoʻopilikia i kou pilikia o ke koko a me ka hiki ke hoʻōla. E hōʻoia e haʻi i kāu kauka e pili ana i kāu mālama ʻana i ka maʻi diabetes, me nā lāʻau lapaʻau āu e lawe ai a me ka maikaʻi o ka mālama ʻana i kou pae kō koko.

He aha kaʻu e hana ai inā lawe hewa au i ka nui o Prasugrel?

Inā lawe hewa ʻoe i ka nui o prasugrel ma mua o ka mea i kauoha ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena mana ʻawaʻawa, ʻoiai inā maikaʻi ʻoe. ʻO ka lawe ʻana i ka nui hiki ke hoʻonui nui i kou pilikia o ke koko no kekahi mau lā. Mai ho'āʻo e hana iā ʻoe iho e luaʻi a i ʻole e lawe i nā lāʻau lapaʻau ʻē aʻe me ka ʻole o ke alakaʻi olakino.

E nānā i nā hōʻailona o ke koko nui e like me ka ʻeha maʻamau, ke koko lōʻihi mai nā ʻoki, ke koko i loko o kou mimi a i ʻole ka ʻōpala, a i ʻole nā ​​poʻo nui. Inā loaʻa iā ʻoe kekahi koko koʻikoʻi, e kelepona koke iā 911. E mālama i ka hue lāʻau me ʻoe i ka wā e ʻimi ai i ka mālama olakino i ʻike pono nā mea mālama ola i ka mea a me ka nui āu i lawe ai.

He aha kaʻu e hana ai inā haʻalele au i kahi mahele o Prasugrel?

Inā haʻalele ʻoe i kahi mahele o prasugrel, e lawe iā ia i ka wā e hoʻomanaʻo ai ʻoe, ke ʻole kokoke i ka manawa no kāu mahele i hoʻonohonoho ʻia. I kēlā hihia, e lele i ka mahele i haʻalele ʻia a lawe i kāu mahele aʻe i ka manawa maʻamau. Mai lawe i ʻelua mahele i ka manawa hoʻokahi e hoʻopiha ai i kahi mahele i haʻalele ʻia, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o ke koko.

E hoʻāʻo e hoʻokumu i kahi hana maʻamau e kōkua iā ʻoe e hoʻomanaʻo e lawe i kāu lāʻau i kēlā me kēia lā. Manaʻo kekahi poʻe he mea kōkua ke lawe i ka prasugrel i ka manawa like e palaki ai lākou i ko lākou niho a i ʻole e ʻai i ka ʻaina kakahiaka. Inā poina pinepine ʻoe i nā lāʻau, e kamaʻilio me kāu kauka e pili ana i nā hoʻolālā e kōkua iā ʻoe e hoʻomanaʻo a i ʻole e noʻonoʻo e hoʻohana i kahi mea hoʻonohonoho pila a i ʻole ka mea hoʻomanaʻo kelepona.

Iā manawa e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Prasugrel?

Pono ʻoe e hooki i ka lawe ʻana i ka prasugrel ke haʻi aku kāu kauka iā ʻoe he palekana ke hana pēlā. Aia ka manawa i kāu kūlana pilikino, akā lawe ka hapa nui o nā kānaka iā ia no ka liʻiliʻi o 12 mau mahina ma hope o kā lākou hana puʻuwai. E loiloi mau kāu kauka i kou pilikia o nā ʻōpala koko e kūʻē i kou pilikia o ke kahe ʻana e hoʻoholo i ka manawa kūpono e hooki ai.

Inā pono ʻoe i ke ʻoki a i ʻole ka hana niho, hiki i kāu kauka ke hooki i ka prasugrel no ka manawa e hōʻemi i ka pilikia o ke kahe ʻana. Mai hooki i ka lāʻau lapaʻau ma kāu iho, ʻoiai no nā kaʻina hana, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o nā ʻōpala koko. E kūkākūkā mau i nā kaʻina hana i hoʻolālā ʻia me kāu cardiologist a me ke kauka e hana ana i ke kaʻina hana.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Prasugrel?

ʻOi aku ka maikaʻi e kaupalena i ka ʻai ʻana i ka waiʻona i ka wā e lawe ana i ka prasugrel, no ka mea, hiki i ka waiʻona ke hoʻonui i kou pilikia o ke kahe ʻana. Manaʻo ʻia ka ʻai ʻana i ka waiʻona (ʻaʻole ʻoi aku ma mua o hoʻokahi inu i kēlā me kēia lā no nā wahine a me ʻelua mau mea inu i kēlā me kēia lā no nā kāne) no ka hapa nui o nā kānaka, akā pono ʻoe e kūkākūkā i kēia me kāu kauka e pili ana i kāu kūlana.

Hiki i ka inu nui ke hoʻonui nui i kou pilikia o ke kahe ʻana a hiki nō hoʻi ke hoʻopilikia i ka hana ʻana o ka prasugrel. Inā he moʻolelo kou o ka hoʻohana ʻana i ka waiʻona nui, e hōʻoia e kūkākūkā i kēia me kāu kauka, no ka mea, hiki iā ia ke hoʻopilikia i kāu hoʻolālā lapaʻau. Hiki i kāu kauka ke hāʻawi i ke alakaʻi pilikino e pili ana i kou olakino holoʻokoʻa a me nā mea pilikia.