He aha ka Pyrazinamide: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau antibiotic ka Pyrazinamide i hoʻolālā ʻia e hakakā i ka maʻi bacteria tuberculosis (TB). Hana kēia lāʻau lapaʻau ma ke ʻano he ʻāpana o kahi ala lapaʻau hui, hui pū ʻia me nā lāʻau TB ʻē aʻe e hoʻomaʻemaʻe pono i ka maʻi mai kou kino.

E lawe maʻamau ʻoe i ka pyrazinamide no kekahi mau mahina e like me ke kuhikuhi a kāu kauka. Pono ka lapaʻau i ke ahonui a me ke kūpaʻa, akā ua kōkua kēia lāʻau lapaʻau i nā miliona o nā kānaka e ola mai ka TB ke hoʻohana pono ʻia.

He aha ka Pyrazinamide?

No ka hui o nā lāʻau lapaʻau i kapa ʻia he mau mea antitubercular ka Pyrazinamide. Ua hoʻolālā ʻia e kuhikuhi i ka bacteria kikoʻī e hoʻoulu ai i ka tuberculosis, e kōkua ana i kāu ʻōnaehana pale e hakakā i kēia maʻi koʻikoʻi.

Hana maikaʻi kēia lāʻau lapaʻau ke mahele a ulu ikaika nā bacteria tuberculosis. Hoʻopilikia ia i ko lākou hiki ke hana hou, e maʻalahi ai no nā pale kūlohelohe o kou kino a me nā lāʻau TB ʻē aʻe e hoʻopau loa i ka maʻi.

ʻAʻole ʻoe e lawe i ka pyrazinamide wale nō no ka mālama ʻana i ka TB. Kauoha mau nā kauka iā ia me nā lāʻau tuberculosis ʻē aʻe e pale ai i ka bacteria mai ka hoʻomohala ʻana i ke kūpaʻa i kekahi lāʻau lapaʻau.

No ke aha e hoʻohana ʻia ai ka Pyrazinamide?

Hoʻomaʻamaʻa ʻo Pyrazinamide i nā maʻi tuberculosis ikaika i kou mau māmā, nā ʻōpū lymph, a i ʻole nā ​​ʻāpana ʻē aʻe o kou kino. He mea maikaʻi loa ia i nā mahina mua o ka mālama ʻana i ka TB i ka wā e kiʻekiʻe ai nā ukana bacterial.

Hiki i kāu kauka ke kuhikuhi i kēia lāʻau lapaʻau inā loaʻa iā ʻoe ka pulmonary tuberculosis (TB i kou mau māmā) a i ʻole extrapulmonary tuberculosis (TB ma waho o kou mau māmā). Pono nā ʻano ʻelua i ke ala like, multi-drug e hōʻoia i ka hoʻōla piha.

I kekahi manawa hoʻohana nā kauka i ka pyrazinamide no ka mālama ʻana i ka TB latent, ʻoiai ʻaʻole maʻamau kēia. ʻO ka TB latent ke manaʻo nei e lawe ʻoe i ka bacteria akā ʻaʻohe ou hōʻailona ikaika.

Pehea e hana ai ka Pyrazinamide?

Ua manaʻo ʻia ʻo Pyrazinamide he lāʻau lapaʻau anti-TB ikaika waena e hana ana ma ka hoʻololi ʻana i kahi ʻano hana i loko o ka bacteria TB. Ke hoʻāla ʻia, keakea ia i ka hiki o ka bacteria ke mālama i ko lākou pā pale waho.

He mea pono loa ka lāʻau lapaʻau i nā wahi acidic, e kū pinepine ana i nā wahi o ka maʻi TB ikaika. ʻO kēia ka mea e pono ai no ka mālama ʻana i ka TB ma nā wahi e like me nā lua māmā kahi e hana ai ka mumū i nā kūlana acidic.

Ke hui pū ʻia me nā lāʻau TB ʻē aʻe, kōkua ʻo pyrazinamide e hōʻemi i kou manawa lapaʻau mai 9 mahina a i 6 mahina. Pale kēia ʻano hui i ka bacteria mai ka hoʻomohala ʻana i ke kūʻē ʻana i kekahi lāʻau lapaʻau.

Pehea wau e lawe ai iā Pyrazinamide?

E lawe iā pyrazinamide e like me ke kauoha a kāu kauka, maʻamau hoʻokahi manawa i ka lā me ke aniani wai piha. Hiki iā ʻoe ke lawe me ka ʻole o ka meaʻai, ʻoiai ʻo ka lawe ʻana me nā meaʻai e kōkua i ka hōʻemi ʻana i ka ʻōpū.

E ale i nā papa holoʻokoʻa me ka ʻole o ka ʻoki ʻana, ka haki ʻana, a i ʻole ka nau ʻana iā lākou. Inā pilikia ʻoe i ka ale ʻana i nā pila, e kamaʻilio me kāu kauka lāʻau lapaʻau e pili ana inā hiki ke palekana i nā papa a i ʻole inā loaʻa nā koho wai.

E hoʻāʻo e lawe i kāu lāʻau lapaʻau i ka manawa like i kēlā me kēia lā e mālama i nā pae kūlike i loko o kou kahe koko. Hiki i ka hoʻonohonoho ʻana i kahi alarm i kēlā me kēia lā ke kōkua iā ʻoe e hoʻomanaʻo i kēia hana maʻamau.

Mai haʻalele i nā meaʻai a i ʻole e hooki i ka lawe ʻana iā pyrazinamide i ka wā mua, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi. Hiki i ka bacteria TB ke kūʻē i ka lapaʻau inā ʻaʻole ʻoe e hoʻopau i ke ala piha i kauoha ʻia e kāu kauka.

Pehea ka lōʻihi e lawe ai au iā Pyrazinamide?

Lawe ka hapa nui o nā kānaka iā pyrazinamide no nā mahina 2 mua o kā lākou lapaʻau TB, ʻoiai e hoʻoholo kāu kauka i ka lōʻihi pololei e pili ana i kāu kūlana kikoʻī. ʻO ka lapaʻau TB holoʻokoʻa e mau ana ma kahi o 6 mahina me nā lāʻau lapaʻau he nui.

E nānā kāu kauka i kou holomua me nā hoʻokolohua koko maʻamau a me nā X-ray umauma e hōʻoia i ka hana pono ʻana o ka lāʻau. Kōkua kēia mau hoʻokolohua i ka hoʻoholo ʻana i ka manawa e palekana ai ke hooki i ka pyrazinamide a hoʻomau me nā lāʻau TB ʻē aʻe.

Pono paha kekahi poʻe me nā maʻi TB paʻakikī i nā manawa lapaʻau lōʻihi. E kūkākūkā kāu kauka i nā hoʻonui lapaʻau me ʻoe a wehewehe i ke kumu e pono ai ka manawa hou no kou ola piha.

He aha nā hopena ʻaoʻao o Pyrazinamide?

E like me nā lāʻau lapaʻau a pau, hiki i ka pyrazinamide ke hana i nā hopena ʻaoʻao, ʻoiai he nui ka poʻe e ʻae maikaʻi iā ia. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e manaʻoʻiʻo i kāu lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau i ʻike ʻia e ka poʻe he nui:

• Nausea a i ʻole ka ʻōpū ʻoluʻolu
• Ka nalowale o ka ʻai
• ʻEha hui a i ʻole nā ʻeha ʻiʻo
• Luhi māmā
• Hoʻonui i ka naʻau i ka lā

Hoʻomaikaʻi pinepine kēia mau hopena maʻamau i ka wā e hoʻoponopono ai kou kino i ka lāʻau i nā pule mua o ka lapaʻau.

Pono nā hopena ʻaoʻao koʻikoʻi i ka lāʻau lapaʻau koke, ʻoiai ʻaʻole lākou e hana pinepine:

• Melemele o ka ʻili a i ʻole nā maka (jaundice)
• ʻEha ʻōpū nui
• Mimi ʻeleʻele a i ʻole nā noho palupalu
• Pāpaʻa mau
• ʻEha hui nui me ka pehu
• Pāpaʻa ʻili a i ʻole ka ʻūlū nui

Inā ʻike ʻoe i kekahi o kēia mau hōʻailona koʻikoʻi, e hoʻokaʻaʻike koke i kāu kauka. Kōkua nā hoʻokolohua koko maʻamau i ka wā o ka lapaʻau e hopu i nā pilikia ate i ka wā.

ʻO nā hopena ʻaoʻao laha akā koʻikoʻi e koi ai i ka mālama ulia pōpilikia:

• Nā hopena maʻi maʻi koʻikoʻi me ka pilikia o ka hanu
• ʻO ka pōʻino ate nui me ka luhi nui a me ka huikau
• Nā maʻi koko e hana ana i ka ʻeha a i ʻole ke kahe koko
• Nā hopena ʻili koʻikoʻi me ka ʻōpū

He pilikia kakaikahi kēia e pili ana i ka poʻe liʻiliʻi, akā, ʻo ka ʻike ʻana i nā hōʻailona hōʻike e kōkua ana e hōʻoia e loaʻa koke iā ʻoe ke kōkua inā pono.

ʻO wai ka mea pono ʻole e lawe i ka Pyrazinamide?

Pono kekahi poʻe e pale i ka pyrazinamide ma muli o ka piʻi ʻana o nā pilikia koʻikoʻi. E nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana i kēia lāʻau.

ʻAʻole pono ʻoe e lawe i ka pyrazinamide inā loaʻa iā ʻoe:

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• Maʻi ate koʻikoʻi a i ʻole hepatitis ikaika
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• ʻIke ʻia ka maʻi i ka pyrazinamide a i ʻole nā lāʻau like
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• Gout acute a i ʻole ka mōʻaukala o nā hōʻeha gout koʻikoʻi
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• Maʻi kīkī koʻikoʻi
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ʻO ka poʻe me kēia mau maʻi e loaʻa pinepine i nā ʻano lapaʻau TB ʻē aʻe ʻaʻole i komo i ka pyrazinamide.

E hoʻohana kāu kauka i ka mālama keu inā loaʻa iā ʻoe:

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• Nā pilikia ate māmā a i ʻole kaulike
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• Mōʻaukala o ka hoʻohana ʻana i ka waiʻona
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• Diabetes
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• Maʻi kīkī
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• Gout a i ʻole nā pae waikawa uric kiʻekiʻe
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• Hāpai a i ʻole ka hānai ʻana i ka waiū
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ʻAʻole pono kēia mau maʻi e pale i ka hoʻohana ʻana i ka pyrazinamide, akā pono lākou i ka nānā ʻana a me nā ʻano lāʻau i hoʻoponopono ʻia.

Nā inoa inoa Pyrazinamide

Ma ʻAmelika Hui Pū ʻIa, loaʻa ka pyrazinamide ma ke ʻano he lāʻau maʻamau. Hiki iā ʻoe ke ʻike iā ia i helu ʻia ma ke ʻano he

ʻO nā koho ʻē aʻe e komo pū ana me ka hoʻolōʻihi ʻana i ka mālama ʻana me ka isoniazid a me ka rifampin mai 6 mahina a 9 mahina. Hiki nō hoʻi i kāu kauka ke noʻonoʻo e hoʻohui i ka ethambutol a i ʻole streptomycin i kāu ʻōnaehana lapaʻau.

No ka poʻe me ka TB kūʻē i ka lāʻau, pono paha nā lāʻau lapaʻau kūikawā e like me fluoroquinolones a i ʻole nā lāʻau injectable laina lua. Pono kēia mau lapaʻau i ka nānā pono ʻana e nā loea TB.

Aia ke koho o nā koho ʻē aʻe i kāu kūlana kikoʻī, me nā lāʻau TB i maʻalahi ai ka bacteria a me kou olakino holoʻokoʻa.

Ua ʻoi aku ka maikaʻi o Pyrazinamide ma mua o Ethambutol?

He ʻokoʻa nā hana a Pyrazinamide a me ethambutol i ka mālama ʻana i ka TB, no laila ʻaʻole maʻalahi ka hoʻohālikelike ʻana iā lākou. He mau ʻāpana koʻikoʻi nā lāʻau lapaʻau ʻelua i ka lāʻau TB piha.

He mea maikaʻi loa ʻo Pyrazinamide i nā mahina mua 2 o ka mālama ʻana i ka wā e kiʻekiʻe ai nā ukana bacterial. Kōkua ia i ka hoʻopōkole ʻana i ka manawa lapaʻau holoʻokoʻa a hana maikaʻi i nā wahi acidic kahi e hūnā pinepine ai ka bacteria TB.

Hoʻohana pinepine ʻia ʻo Ethambutol i ka wā o ka mālama ʻana a pau a kōkua i ka pale ʻana i ke kūʻē ʻana i nā lāʻau TB ʻē aʻe. Koho pinepine ʻia no ka poʻe ʻaʻole hiki ke ʻae i ka pyrazinamide ma muli o nā pilikia o ke ake.

Koho kāu kauka i ka hui maikaʻi loa o nā lāʻau lapaʻau e pili ana i kāu ʻano TB kikoʻī, nā kūlana olakino, a me nā pahuhopu lapaʻau. Ua hōʻoia ʻia nā moʻolelo o nā lāʻau lapaʻau ʻelua i ka mālama ʻana i ka TB ke hoʻohana pono ʻia.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Pyrazinamide

He Palekana ʻo Pyrazinamide no nā Wahine Hāpai?

Manaʻo ʻia ʻo Pyrazinamide he palekana i ka wā o ka hāpai ʻana i ka mālama ʻana i ka maʻi tuberculosis. ʻOi aku ka maikaʻi o ka mālama ʻana i ka TB i ka wā o ka hāpai ʻana ma mua o nā pilikia i ka makuahine a me ka pēpē.

Eia naʻe, e noʻonoʻo pono kāu kauka i nā pilikia a me nā pōmaikaʻi i kāu kūlana kikoʻī. Makemake kekahi mau kauka i nā ʻōnaehana lapaʻau TB ʻē aʻe i ka wā o ka hāpai ʻana, ʻoiai ʻoluʻolu kekahi poʻe e hoʻohana i ka pyrazinamide ke pono.

He aha kaʻu e hana ai inā ua lawe hewa au i ka nui o ka Pyrazinamide?

Inā ua lawe hewa ʻoe i ka nui o ka pyrazinamide ma mua o ka mea i kauoha ʻia, e kelepona koke i kāu kauka a i ʻole ke kikowaena mana ʻawa. ʻO ka lawe ʻana i ka nui hiki ke hoʻonui i kou pilikia o ka pōʻino o ke ake a me nā hopena ʻē aʻe.

Mai kali a hiki i ka hōʻike ʻana o nā hōʻailona ma mua o ka ʻimi ʻana i ke kōkua. E lawe mai i ka ʻōmole lāʻau me ʻoe inā pono ʻoe e kipa i kahi lumi ulia pōpilikia, no ka mea, kōkua kēia i nā limahana lapaʻau e hoʻomaopopo pono i ka mea a me ka nui āu i lawe ai.

He aha kaʻu e hana ai inā ua hala au i kahi mahele o Pyrazinamide?

Inā ua hala ʻoe i kahi mahele, e lawe koke iā ia ke hoʻomanaʻo ʻoe, ke ʻole kokoke ka manawa no kāu mahele i hoʻonohonoho ʻia. Mai lawe i ʻelua mahele i ka manawa hoʻokahi e hoʻopiha i kahi mahele i hala.

Inā ʻaʻole ʻoe maopopo e pili ana i ka manawa, e kelepona i kāu kauka a i ʻole ka mea kūʻai lāʻau lapaʻau no ke alakaʻi. He mea nui ka mālama ʻana i nā pae lāʻau lapaʻau kūlike no ka mālama ʻana i ka TB maikaʻi, no laila e hoʻāʻo e hoʻokumu i kahi hana maʻamau e kōkua iā ʻoe e hoʻomanaʻo i kāu mahele i kēlā me kēia lā.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Pyrazinamide?

E hooki wale i ka lawe ʻana i ka pyrazinamide ke haʻi kāu kauka iā ʻoe he palekana ke hana pēlā. Hana maʻamau kēia ma hope o 2 mau mahina o ka mālama ʻana, a laila e hoʻomau ʻoe me nā lāʻau TB ʻē aʻe no ke koena o kāu lāʻau lapaʻau.

E hoʻohana kāu kauka i nā hoʻokolohua koko, nā X-ray umauma, a me nā moʻomeheu sputum e hoʻoholo ai i ka manawa kūpono e hooki ai i ka pyrazinamide. ʻO ka hooki ʻana i ka wā mua hiki ke alakaʻi i ka hāʻule ʻana o ka lāʻau lapaʻau a me ka TB kūʻē i ka lāʻau.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Pyrazinamide?

ʻOi aku ka maikaʻi e pale loa i ka waiʻona i ka wā e lawe ana i ka pyrazinamide. Hiki i ka waiʻona a me ka pyrazinamide ke hoʻopilikia i kou ake, a ʻo ka hui pū ʻana iā lākou e hoʻonui i kou pilikia o ka pōʻino o ke ake.

Inā he hopohopo kāu e pili ana i ka hoʻohana ʻana i ka waiʻona i ka wā o ka mālama ʻana i ka TB, e kūkākūkā ākea me kāu kauka. Hiki iā lākou ke hāʻawi i ke kākoʻo a me nā kumuwaiwai e kōkua iā ʻoe e mālama i ka maʻemaʻe i ka wā o kou manawa hoʻōla.