He aha ka Quinupristin a me ka Dalfopristin: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Quinupristin a me dalfopristin he hui pū ʻana o nā lāʻau antibiotic ikaika e hoʻohana ai nā kauka e mālama i nā maʻi bacteria koʻikoʻi i ka wā i hana ʻole ai nā lāʻau antibiotic ʻē aʻe. No ka papa i kapa ʻia ʻo streptogramins kēia lāʻau lapaʻau, a hāʻawi ʻia ma o ka laina IV (intravenous) pololei i loko o kou kahe koko.

Hoʻokaʻawale ʻia kēia hui pū ʻana o nā antibiotic no nā maʻi paʻakikī, ʻo ia hoʻi nā mea i hana ʻia e nā bacteria kūʻē. E noʻonoʻo pono kāu kauka i kēia koho lapaʻau i ka wā e hana ai me nā ʻano maʻi bacteria koʻikoʻi e pono ai ka nānā koke.

He aha ka Quinupristin a me Dalfopristin?

ʻO Quinupristin a me dalfopristin he hui pū ʻana o nā antibiotic ʻelua e hana pū ana ma ke ʻano he hui e hakakā i nā maʻi bacteria. E noʻonoʻo iā ia he kuʻi hoʻokahi-ʻelua i nā bacteria ʻino i hōʻoia i ke kūʻē ʻana i nā lāʻau lapaʻau ʻē aʻe.

Hele mai ka lāʻau lapaʻau ma ke ʻano he pauka e hui pū ai nā limahana o ka haukapila me ka wai sterile ma mua o ka hāʻawi ʻana iā ʻoe ma o ka IV. He mea maikaʻi loa kēia hui pū ʻana i nā bacteria gram-positive, ʻo ia nā ʻano bacteria e hoʻoulu ai i nā maʻi koʻikoʻi.

Ua manaʻo ʻia kēia antibiotic he lāʻau ikaika, ʻo ia hoʻi, hoʻohana ʻia ia i ka wā i hana ʻole ai nā antibiotic ʻē aʻe, ʻoluʻolu. E nānā pono kāu hui mālama ola iā ʻoe i ka wā e loaʻa ai iā ʻoe kēia lapaʻau.

No ke aha e hoʻohana ʻia ai ka Quinupristin a me Dalfopristin?

Hoʻomaʻamaʻa kēia hui pū ʻana o nā antibiotic i nā maʻi ʻili a me nā maʻi ʻiʻo palupalu i hana ʻia e nā bacteria kikoʻī. Hiki i kāu kauka ke kuhikuhi iā ia i ka wā e loaʻa ai iā ʻoe nā maʻi paʻakikī i pane ʻole i nā antibiotic ʻē aʻe.

He mea maikaʻi loa ka lāʻau lapaʻau i kekahi mau ʻano bacteria e hiki ke hoʻoulu i nā maʻi e hoʻoweliweli ana i ke ola. Eia nā kūlana nui e mālama ai:

• Nā maʻi ʻili a me nā maʻi o ke ʻano o ka ʻili
• Nā maʻi i hana ʻia e Enterococcus faecium (he ʻano bacteria kūʻē i ka vancomycin)
• Nā maʻi i hana ʻia e Staphylococcus aureus (me kekahi mau ʻano kūʻē i ka methicillin)
• Nā maʻi i hana ʻia e Streptococcus pyogenes

Na kāu mea mālama ola e hoʻoholo inā kūpono kēia lāʻau lapaʻau no kāu maʻi kikoʻī e pili ana i nā hoʻokolohua lab a me kāu moʻolelo olakino. Hōʻoia kēia e loaʻa iā ʻoe ka lāʻau lapaʻau kūpono loa no kou maʻi.

Pehea e hana ai ʻo Quinupristin a me Dalfopristin?

Hana kēia hui antibiotic ma ka hoʻōki ʻana i ka bacteria mai ka hana ʻana i nā protein e pono ai lākou e ola a hoʻonui. Ke hiki ʻole i ka bacteria ke hana i kēia mau protein koʻikoʻi, make lākou, e ʻae ana i nā pale kūlohe o kou kino e hoʻomaʻemaʻe i ka maʻi.

Hana nā ʻāpana ʻelua i kahi ala synergistic, ʻo ia hoʻi, ʻoi aku ka maikaʻi o lākou i ka hui pū ʻana ma mua o ka hoʻokahi wale nō. Hoʻopili ʻo Quinupristin a me dalfopristin i nā ʻāpana like ʻole o ka mīkini hana protein bacterial, e hana ana i kahi poloka pālua i paʻakikī loa ka bacteria e lanakila ai.

Ua manaʻo ʻia he antibiotic ikaika kēia no ka mea hiki iā ia ke komo i nā pale bacterial i hoʻomohala i ke kūʻē ʻana i nā lāʻau lapaʻau ʻē aʻe. Eia naʻe, ʻo kēia ikaika hoʻi ke ʻano e pono ai ka nānā pono ʻana i ka wā o ka mālama ʻana.

Pehea wau e lawe ai iā Quinupristin a me Dalfopristin?

E loaʻa iā ʻoe kēia lāʻau lapaʻau ma kahi haukapila a i ʻole kahi hoʻonohonoho lapaʻau ma o ka laina IV. E hoʻomākaukau a lawelawe ka hui mālama ola iā ia nāu, no laila ʻaʻole pono ʻoe e hopohopo e lawe iā ʻoe iho.

Hāʻawi ʻia ka lāʻau lapaʻau i kēlā me kēia 8 a i ʻole 12 mau hola, ma muli o kou maʻi kikoʻī a me ke ʻano o kou kino e pane ai. Lawe maʻamau kēlā me kēia infusion ma kahi o 60 mau minuke, i ka wā e nānā ʻia ai ʻoe no nā hopena.

ʻAʻole pono ʻoe e pale i ka meaʻai a i ʻole ka mea inu i ka wā e loaʻa ana kēia lāʻau lapaʻau, akā hiki i kāu hui mālama ola ke loaʻa nā ʻōlelo paipai kikoʻī e pili ana i kāu hoʻolālā lapaʻau holoʻokoʻa. Hāʻawi ka laina IV i ka lāʻau lapaʻau e hele pololei i loko o kou kahe koko, e pale loa ana i kāu ʻōnaehana digestive.

Pehea ka lōʻihi e lawe ai au i ka Quinupristin a me Dalfopristin?

ʻO ka lōʻihi o ka lapaʻau maʻamau mai 7 a 14 mau lā, ma muli o ke koʻikoʻi o kāu maʻi a me ka maikaʻi o kāu pane ʻana i ka lāʻau lapaʻau. E nānā kāu kauka i kou holomua a hoʻoponopono i ka lōʻihi e like me ka mea e pono ai.

Hiki i kekahi mau maʻi ke koi i nā manawa lapaʻau pōkole, ʻoiai ʻo nā maʻi koʻikoʻi a paʻakikī paha e pono ai nā papa lōʻihi. E hoʻohana kāu hui mālama ola i nā hoʻokolohua lab a me kāu hoʻomaikaʻi ʻana i ka maʻi e hoʻoholo ai i ka lōʻihi kūpono no ʻoe.

He mea nui e hoʻopau i ka papa lapaʻau holoʻokoʻa, ʻoiai inā hoʻomaka ʻoe e ʻoi aku ka maikaʻi ma mua o ka pau ʻana. ʻO ka hoʻōki ʻana i nā lāʻau antibiotic i ka wā mua e hiki ai i ka bacteria ke hoʻi mai a hiki ke hoʻomohala i ke kūpaʻa i ka lāʻau lapaʻau.

He aha nā hopena ʻaoʻao o Quinupristin a me Dalfopristin?

E like me nā lāʻau lapaʻau a pau, hiki i ka quinupristin a me ka dalfopristin ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole nā ​​mea a pau e ʻike iā lākou. Hiki ke hoʻokele ʻia ka hapa nui o nā hopena ʻaoʻao, a e nānā pono kāu hui mālama ola iā ʻoe i ka wā o ka lapaʻau.

Eia nā hopena ʻaoʻao maʻamau loa e ʻike ai ʻoe:

• ʻEha, huhū, a i ʻole ka mumū ma ka pūnaewele IV
• ʻEha ʻiʻo a me ka ʻeha hui
• Nausea a me ka luaʻi
• Pāpaʻa
• Poʻo
• ʻO ka ʻōpala a i ʻole nā ​​hopena ʻili

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau. E nānā kāu hui mālama ola i nā hōʻailona o kēia mau mea a e hana i ka hana kūpono inā loaʻa lākou:

• Nā hopena maʻi koʻikoʻi
• Nā loli hana ate
• Nā loli puʻuwai
• ʻEha ʻiʻo koʻikoʻi a i ʻole nāwaliwali
• Paʻakikī ka hanu

Inā ʻike ʻoe i nā hōʻailona ʻokoʻa a i ʻole e hopohopo ana i ke ʻano o kāu pane ʻana i ka lāʻau lapaʻau, mai kānalua e haʻi koke i kāu hui mālama ola. Aia lākou ma laila e hōʻoia i kou palekana a me kou hōʻoluʻolu i ka wā o ka mālama ʻana.

ʻO wai ka mea pono ʻole e lawe iā Quinupristin a me Dalfopristin?

ʻAʻole kūpono kēia lāʻau lapaʻau no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana. Hiki i kekahi mau maʻi a i ʻole nā ​​kūlana ke hana i kēia antibiotic kūpono ʻole no kou kūlana.

ʻAʻole pono ʻoe e loaʻa i kēia lāʻau lapaʻau inā he maʻi ʻoe i ka quinupristin, dalfopristin, a i ʻole kekahi mea o ka lāʻau lapaʻau. E nīnau kāu hui mālama ola e pili ana i nā hopena maʻi ma mua o ka hoʻomaka ʻana i ka mālama ʻana.

Pono paha ka poʻe me kekahi mau maʻi i nā hana kūikawā a i ʻole nā ​​lāʻau lapaʻau ʻē aʻe. E noʻonoʻo pono kāu kauka i kēia mau mea:

• Maʻi ate a i ʻole nā ​​pilikia o ka hana ate
• Nā maʻi puʻuwai
• Nā maʻi ʻiʻo a i ʻole nā ​​pilikia ʻiʻo ma mua mai nā lāʻau lapaʻau
• Hāpai a i ʻole ka hānai ʻana (pono i ka loiloi pilikia-pōmaikaʻi)
• Maʻi kīkī (pono paha i ka hoʻoponopono ʻana i ka dosage)

E nānā pū kāu mea mālama ola i nā lāʻau lapaʻau a pau āu e lawe nei i kēia manawa, no ka mea, hiki i kekahi mau lāʻau lapaʻau ke launa pū me ka quinupristin a me ka dalfopristin. Hoʻomaopopo kēia loiloi piha i kou palekana i ka wā o ka mālama ʻana.

ʻO nā inoa inoa o Quinupristin a me Dalfopristin

ʻO ka inoa inoa no kēia hui lāʻau lapaʻau ʻo Synercid. ʻO kēia ka inoa āu e ʻike ai ma nā moʻolelo haukapila a me nā lepili lāʻau lapaʻau i ka wā o kāu mālama ʻana.

Hoʻohana pinepine nā mea mālama ola i ka inoa generic (quinupristin a me dalfopristin) a me ka inoa inoa (Synercid) i nā mea like. E pili ana nā mea ʻelua i ka hui lāʻau lapaʻau like, no laila, mai huikau inā lohe ʻoe i nā inoa like ʻole.

Nā koho ʻē aʻe o Quinupristin a me Dalfopristin

He nui nā lāʻau antibiotic ʻē aʻe e hiki ke noʻonoʻo ʻia ma ke ʻano he koho ʻē aʻe, ma muli o kāu maʻi kikoʻī a me ke kūlana olakino. E koho kāu kauka ma muli o ke ʻano o ka bacteria e hoʻoulu ana i kāu maʻi a me nā mea olakino pilikino.

ʻO kekahi mau lāʻau antibiotic ʻē aʻe e hiki ke noʻonoʻo ʻia, ʻo ia:

• Linezolid (no nā maʻi gram-positive kūʻē)
• Daptomycin (no kekahi mau maʻi ʻili a me nā maʻi ʻiʻo palupalu)
• Tigecycline (no nā maʻi paʻakikī)
• Vancomycin (no kekahi mau ʻano bacteria kūʻē)
• Clindamycin (no nā maʻi ʻili kikoʻī)

Aia ke koho ʻana i nā koho ʻē aʻe ma nā mea he nui, me ka bacteria kikoʻī i pili, kāu mōʻaukala olakino, a me ka maikaʻi o kāu pane ʻana i nā lāʻau lapaʻau ʻē aʻe. E koho kāu hui mālama ola i ke koho kūpono loa no kou kūlana kūikawā.

Ua ʻoi aku ka maikaʻi o Quinupristin a me Dalfopristin ma mua o Vancomycin?

Aia inā ʻoi aku ka maikaʻi o quinupristin a me dalfopristin ma mua o vancomycin ma muli o kāu maʻi kikoʻī a me ka bacteria e hoʻoulu ana. He mau lāʻau antibiotic ikaika ʻelua i hoʻohana ʻia no nā maʻi koʻikoʻi, akā hana lākou ma nā ʻano like ʻole a kūʻē i nā ʻano bacteria like ʻole.

Hiki ke makemake ʻia ʻo Quinupristin a me dalfopristin i ka wā e hana ana me vancomycin-resistant enterococci (VRE), kahi ʻano bacteria ʻaʻole e pane i ka vancomycin. I kēia mau hihia, hāʻawi kēia hui i kahi koho lapaʻau kūpono i ka wā i hāʻule ai ka vancomycin.

Eia naʻe, ʻo vancomycin paha ke koho maikaʻi loa no nā ʻano maʻi ʻē aʻe, ʻo ia hoʻi nā mea i hoʻokumu ʻia e nā bacteria e maʻalahi iā ia. E hoʻohana kāu kauka i nā hoʻokolohua lab e hoʻoholo ai i nā bacteria e hoʻoulu ana i kāu maʻi a me nā lāʻau antibiotic e ʻoi aku ka maikaʻi iā lākou.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Quinupristin a me Dalfopristin

He palekana anei ʻo Quinupristin a me Dalfopristin no ka poʻe me ka maʻi puʻuwai?

Pono e mālama pono ʻia kēia lāʻau lapaʻau i ka poʻe me ka maʻi puʻuwai, ʻoiai ka poʻe me nā maʻi puʻuwai. Hiki i ka hui pū ʻana ke hoʻopilikia i ka puʻuwai, no laila e nānā pono kāu hui mālama ola i kāu hana puʻuwai i ka wā o ka mālama ʻana.

Inā he moʻolelo kou o nā pilikia puʻuwai, e loiloi kāu kauka i nā pōmaikaʻi o ka mālama ʻana i kāu maʻi i nā pilikia e hiki mai ana i kou puʻuwai. Hiki iā lākou ke hoʻohana i nā mea hana hou a hoʻoponopono i kāu hoʻolālā lapaʻau e like me ia e mālama ai iā ʻoe.

He aha kaʻu e hana ai inā loaʻa iaʻu ka ʻeha ʻiʻo nui i ka wā o ka mālama ʻana?

Hiki i ka ʻeha ʻiʻo nui ke lilo i hopena ʻaoʻao koʻikoʻi e pono ai ka lāʻau lapaʻau koke. Inā loaʻa iā ʻoe nā ʻeha ʻiʻo nui, nāwaliwali, a i ʻole ka ʻeha e like me ka mea maʻamau a koʻikoʻi paha, e hoʻomaopopo koke i kāu hui mālama ola.

Pono paha kāu hui lapaʻau e hoʻoponopono i kāu lapaʻau a i ʻole e hāʻawi i nā lāʻau lapaʻau hou e mālama i kēia mau hōʻailona. Mai hoʻāʻo e hoʻoikaika i ka ʻeha ʻiʻo nui, no ka mea, hiki i kēia ke hōʻike i kahi hopena koʻikoʻi e pono ai ka nānā koke.

He aha ka mea e hana ai inā haʻalele au i kahi mahele o Quinupristin a me Dalfopristin?

No ka mea e loaʻa iā ʻoe kēia lāʻau lapaʻau i loko o kahi haukapila a i ʻole kahi hoʻonohonoho lapaʻau, mālama kāu hui mālama ola i ka manawa o nā mahele āpau. Loaʻa iā lākou nā ʻōnaehana e hōʻoia ai e loaʻa iā ʻoe kāu lāʻau lapaʻau i ka manawa.

Inā no kekahi kumu e lohi ai kahi mahele ma muli o nā kaʻina hana lapaʻau a i ʻole nā ​​kūlana ʻē aʻe, e hoʻoponopono kāu hui mālama ola i ka manawa kūpono. ʻAʻole pono ʻoe e hopohopo e pili ana i ka haʻalele ʻana i nā mahele no ka mea e mālama ana nā poʻe loea i kāu papa hana lapaʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Quinupristin a me Dalfopristin?

ʻAʻole pono ʻoe e hooki i kēia lāʻau lapaʻau iā ʻoe iho, ʻoiai inā ʻoe e manaʻo maikaʻi loa. E hoʻoholo kāu kauka i ka wā e palekana ai ke hooki i ka lapaʻau ma muli o kāu hoʻomaikaʻi ʻana i ke olakino a me nā hopena hoʻokolohua lab.

ʻO ka hooki ʻana i nā lāʻau antibiotic ma mua o ka manawa hiki ke ʻae i ka bacteria e hoʻi mai a e hoʻomohala i ka pale ʻana i ka lāʻau. E nānā ana kāu hui mālama ola i kou holomua a e hōʻike iā ʻoe i ka wā i pau ai ʻoe i ka papa piha o ka lapaʻau e pono ai no kou ola hou ʻana.

Hiki iaʻu ke loaʻa i nā lāʻau lapaʻau ʻē aʻe i ka wā e lawe ana i ka Quinupristin a me Dalfopristin?

Hiki ke hāʻawi palekana ʻia nā lāʻau lapaʻau he nui me ka quinupristin a me dalfopristin, akā pono kekahi i nā hana kūikawā a i ʻole nā hoʻoponopono manawa. E nānā kāu hui mālama ola i kāu mau lāʻau lapaʻau a pau e pale aku i nā pilina pōʻino.

Pono paha kekahi mau lāʻau lapaʻau e pili ana i ka puʻuwai a i ʻole ka hana ate i ka nānā kūikawā a i ʻole nā hoʻoponopono maʻi. E hoʻopili kāu hui lapaʻau i kāu mau lapaʻau a pau e hōʻoia i ka hana palekana a me ka maikaʻi no kou ola hou ʻana.