He aha ka Radium Ra 223 Dichloride: Nā Hoʻohana, Nā Ana, Nā hopena ʻaoʻao a me nā mea hou aku

ʻO ka Radium Ra 223 dichloride he lāʻau lapaʻau radioactive kūikawā i hoʻohana ʻia e mālama i kekahi mau ʻano maʻi maʻi prostate i holomua i hohola i nā iwi. Hana kēia ʻano lapaʻau i ka hāʻawi ʻana i ka radiation pololei i nā sela maʻi i loko o ka ʻiʻo iwi, e kōkua ana i ka hoʻolohi ʻana i ka ulu ʻana o ka maʻi a me ka hōʻemi ʻana i ka ʻeha iwi.

Inā ua ʻōlelo kāu kauka i kēia lapaʻau, e hana ana paha ʻoe me ka maʻi prostate kūʻē i ka castration i metastasized i kou mau iwi. ʻOiai he mea nui kēia, ʻo ka radium Ra 223 e hōʻike ana i kahi holomua nui i ka mālama ʻana i ka maʻi maʻi, e hāʻawi ana i ka manaʻolana no ka mālama ʻana i nā hōʻailona a me ka hoʻolōʻihi ʻana i ka maikaʻi o ke ola.

He aha ka Radium Ra 223 Dichloride?

ʻO ka Radium Ra 223 dichloride he mea hoʻopuka alpha particle radioactive e hoʻohālike i ka calcium i kou kino. No ka mea, ʻoi aku ka maʻalahi o nā sela maʻi i loko o nā iwi i ka calcium ma mua o ka ʻiʻo olakino, ua manaʻo maoli kēia lāʻau lapaʻau i nā wahi i hohola ai ka maʻi prostate i kou iwi.

No ka lāʻau lapaʻau i kahi papa i kapa ʻia ʻo radiopharmaceuticals, e hui pū ana i nā mea radioactive me nā mea lapaʻau. ʻAʻole like me ka lāʻau lapaʻau radiation waho e pili ana i nā wahi nui, hāʻawi ka radium Ra 223 i ka radiation pololei, i manaʻo ʻia i nā metastases iwi mai loko mai.

Ua aʻo nui ʻia kēia lāʻau lapaʻau a ua ʻae ʻia no nā kāne me ka maʻi prostate kūʻē i ka castration a me nā metastases iwi. Hōʻike ia i nā makahiki o ka noiʻi ʻana i ka ʻimi ʻana i nā ala ʻoi aku ka maikaʻi e mālama ai i ka maʻi prostate holomua me ka hōʻemi ʻana i nā hopena ʻaoʻao.

No ke aha i hoʻohana ʻia ai ka Radium Ra 223 Dichloride?

Hoʻomaʻamaʻa ka Radium Ra 223 dichloride i ka maʻi prostate kūʻē i ka castration i hohola i nā iwi akā ʻaʻole i nā ʻōkana ʻē aʻe. E ʻōlelo kāu kauka i kēia lapaʻau ke pau kāu maʻi i ka pane ʻana i ka lāʻau hormone a ua hana i nā metastases i kāu ʻōnaehana skeletal.

He mau hana nui ʻelua o ka lāʻau lapaʻau i kāu hoʻolālā lapaʻau. ʻO ka mea mua, hiki iā ia ke kōkua i ka hōʻemi ʻana i ka ʻeha o ka iwi i hana ʻia e nā metastases maʻi ʻaʻai, e hoʻomaikaʻi ana i kou ʻoluʻolu a me ka neʻe ʻana i kēlā me kēia lā. ʻO ka lua, hōʻike nā haʻawina lapaʻau e hiki ke kōkua i ka hoʻolōʻihi i ka manawa ola i hoʻohālikelike ʻia me ka mālama maʻamau wale nō.

E loiloi pono kāu oncologist inā he moho maikaʻi ʻoe no kēia lapaʻau. E noʻonoʻo lākou i nā mea e like me kou olakino holoʻokoʻa, ka nui o ke komo ʻana o ka iwi, a inā ua laha ka maʻi ʻaʻai i nā ʻiʻo palupalu a i ʻole nā ʻōkana ma waho o ka iwi.

Pehea e hana ai ʻo Radium Ra 223 Dichloride?

Hana ʻo Radium Ra 223 dichloride ma ka hana ʻana e like me ka mea hoʻohui calcium e komo koke ai kou mau iwi. Eia naʻe, ma kahi o ka hoʻoikaika ʻana i nā iwi, hāʻawi ia i ka radiation alpha i nā wahi i noho ai nā cell maʻi ʻaʻai prostate i loko o kou ʻiʻo iwi.

He kūpono loa nā ʻāpana alpha i nā cell maʻi ʻaʻai no ka mea e hoʻopili lākou i kahi paʻi ikaika i kahi wahi liʻiliʻi loa. Hele wale kēia mau ʻāpana i kekahi mau lōʻihi o ke keena, ʻo ia hoʻi hiki iā lākou ke luku i nā cell maʻi ʻaʻai me ka hana ʻana i ka pōʻino liʻiliʻi i ka iwi iwi olakino a me nā ʻiʻo.

Hoʻopilikia ka radiation i ka DNA i loko o nā cell maʻi ʻaʻai, e pale ana iā lākou mai ka mahele a me ka ulu ʻana. I ka hala ʻana o ka manawa, hiki i kēia hana ke hōʻemi i nā ʻōpū i loko o kou mau iwi a hōʻemi i ka ʻeha a lākou e hana ai. Manaʻo ʻia ka lapaʻau he mea ikaika, e hāʻawi ana i nā pōmaikaʻi nui me ka maʻamau.

Pehea wau e lawe ai iā Radium Ra 223 Dichloride?

Hāʻawi ʻia ʻo Radium Ra 223 dichloride ma ke ʻano he injection intravenous lohi i loko o ke keʻena o kāu kauka a i ʻole ka haukapila. E loaʻa iā ʻoe ka lāʻau lapaʻau ma o ka laina IV, maʻamau ma luna o 1-2 mau minuke, hoʻokahi i kēlā me kēia ʻehā pule no ka nui o nā mahele ʻeono.

Ma mua o kēlā me kēia lapaʻau, pono ʻoe e pale i ka ʻai ʻana no ka liʻiliʻi o ʻelua hola ma mua o kāu manawa. Kōkua kēia i ka hōʻoia ʻana i ka absorption maikaʻi o ka lāʻau lapaʻau. Hiki iā ʻoe ke inu i ka wai maʻamau ke ʻole e hāʻawi kāu hui mālama ola iā ʻoe i nā ʻōlelo aʻoaʻo like ʻole.

I ka wā o ka hoʻokomo ʻana, e nānā pono ʻia ʻoe e nā limahana lāʻau lapaʻau nukelea i hoʻomaʻamaʻa kūikawā ʻia. Ma hope o ka loaʻa ʻana o ka lāʻau, pono ʻoe e hahai i nā hana palekana kūikawā no kahi pule, me ka holoi lima pono a me ka hoʻomaʻemaʻe lua kūpono e pale aku i nā lālā o ka ʻohana mai nā mea liʻiliʻi o ka radiation.

E hāʻawi kāu hui lapaʻau i nā ʻōlelo kikoʻī e pili ana i nā hana ma hope o ka mālama ʻana. ʻO kēia mau mea e pili ana i ka hoʻohana ʻana i nā keʻena lua kaʻawale ke hiki a me ka holoi ʻana i kou mau lima ma hope o ka hoʻohana ʻana i ka lua.

Pehea ka lōʻihi e lawe ai au i ka Radium Ra 223 Dichloride?

ʻO ke ʻano lapaʻau maʻamau he ʻeono injections i hāʻawi ʻia i ʻehā pule kaʻawale, e hōʻuluʻulu ana i kahi ʻelima mahina o ka mālama ʻana. Ua aʻo ʻia kēia papa manawa a hōʻike i ke kaulike maikaʻi loa ma waena o ka pono a me ka palekana.

Hiki i kāu kauka ke hoʻololi i kēia papa manawa ma muli o ke ʻano o kou pane ʻana i ka lāʻau a me nā hopena ʻaoʻao āu e ʻike ai. Hoʻopau kekahi poʻe maʻi i nā lāʻau a pau ʻeono me ka ʻole o nā pilikia, ʻoiai ʻo nā mea ʻē aʻe e pono ai ka lohi ʻana o ka lāʻau a i ʻole nā hoʻololi ʻana ma muli o nā helu koko a i ʻole nā mea ʻē aʻe.

ʻO ka nānā mau ʻana i ka wā o ka mālama ʻana e kōkua i ka hōʻoia ʻana e ʻae maikaʻi ana ʻoe i ka lāʻau. E nānā kāu hui mālama ola i kāu mau helu koko, ka hana ʻana o nā puʻupaʻa, a me ke olakino holoʻokoʻa ma mua o kēlā me kēia injection e hōʻoia i ka palekana o ka hoʻomau ʻana.

He aha nā hopena ʻaoʻao o Radium Ra 223 Dichloride?

E like me ka hapa nui o nā lāʻau lapaʻau maʻi, hiki i ka radium Ra 223 dichloride ke hana i nā hopena ʻaoʻao, ʻoiai ua ʻae ka nui o nā maʻi iā ia ma mua o ka chemotherapy kuʻuna. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e hoʻomākaukau a ʻike i ka manawa e hoʻopili ai i kāu hui mālama ola.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia ka luhi, ka nausea, ka maʻi maʻi, a me ka emi ʻana o ka ʻai. He maʻalahi a maʻalahi kēia mau hōʻailona a pinepine e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau.

Eia nā hopena ʻaoʻao pinepine e pili ana i nā maʻi he nui:

• ʻO ka luhi a me ka nāwaliwali e mau ana no kekahi mau lā ma hope o kēlā me kēia injection
• ʻO ka nausea a me ka luaʻi ʻana i kekahi manawa, hiki ke mālama ʻia me nā lāʻau anti-nausea
• ʻO ka maʻi palahī e hiki ke mālama ʻia me nā loli meaʻai a me nā lāʻau lapaʻau
• ʻAʻole makemake i ka ʻai a me ka emi ʻana o ke kaumaha
• ʻO ka ʻeha o ka iwi e hiki ke ʻoi aku ka maikaʻi ma mua o ka hoʻomaikaʻi ʻana
• ʻO ka pehu ʻana i nā wāwae, nā kuʻekuʻe wāwae, a i ʻole nā wāwae

Hiki ke mālama ʻia kēia mau hopena ʻaoʻao maʻamau me ka mālama kākoʻo a ʻaʻole pono e hoʻōki i ka lāʻau. E hāʻawi kāu hui mālama ola i nā hoʻolālā e kōkua i ka hōʻemi ʻana i ka hōʻoluʻolu.

Hiki ke loaʻa nā hopena ʻaoʻao koʻikoʻi, akā ʻaʻole maʻamau. Pono kēia mau mea i ka lāʻau lapaʻau koke a me ka nānā pono ʻana i kāu papa hana lapaʻau.

Eia nā hopena ʻaoʻao e pili ana i ka pono e loiloi koke ʻia:

• ʻO ka hāʻule nui ʻana o nā helu keʻena koko, me ka anemia, nā keʻena koko keʻokeʻo haʻahaʻa, a i ʻole nā platelets haʻahaʻa
• ʻO ka piʻi ʻana o ka pilikia o ke kahe ʻana a i ʻole ka ʻeha ma muli o nā helu platelet haʻahaʻa
• ʻOi aku ka maʻalahi i nā maʻi mai ka emi ʻana o nā helu keʻena koko keʻokeʻo
• Nā pilikia o ka puʻupaʻa, ʻoiai ʻaʻole maʻamau kēia
• ʻO ka ʻeha iwi nui ʻaʻole e hoʻomaikaʻi me ka mālama ʻeha maʻamau
• Nā haʻihaʻi i nā iwi nāwaliwali, ʻoi aku hoʻi i nā wahi me nā ʻōpū nui

E nānā pono kāu hui lapaʻau i kēia mau pilikia e hiki mai ana ma o nā hoʻokolohua koko maʻamau a me nā hoʻokolohua kino. ʻO ka ʻike mua a me ka mālama ʻana i nā hopena ʻaoʻao koʻikoʻi e kōkua i ka hōʻoia ʻana i kou palekana i ka wā o ka lapaʻau.

ʻO kekahi mau pilikia kakaʻikahi akā koʻikoʻi e pili ana i ka hoʻopaʻa ʻana i ka iwi iwi nui a me ka piʻi ʻana o ka pilikia o ka haʻihaʻi i nā iwi me nā metastases nui. Loaʻa kēia mau mea i kahi pākēneka liʻiliʻi o nā maʻi akā pono i ka lāʻau lapaʻau koke ke hana lākou.

ʻO wai ka mea pono ʻole e lawe iā Radium Ra 223 Dichloride?

ʻAʻole kūpono ʻo Radium Ra 223 dichloride no nā mea a pau i loaʻa i ka maʻi kanesa prostate. E loiloi pono kāu kauka i kou kūlana kūikawā e hoʻoholo ai inā kūpono kēia lapaʻau iā ʻoe.

ʻAʻole pono ʻoe e loaʻa i kēia lāʻau lapaʻau inā ua laha kou maʻi kanesa prostate i nā ʻōkana ma waho o ka iwi, e like me ke ake, nā māmā, a i ʻole nā ​​ʻōpū lymph. Hoʻolālā ʻia ka lapaʻau no nā metastases iwi wale nō a ʻaʻole pono i ka maʻi ʻiʻo palupalu.

He nui nā kūlana ʻē aʻe e hana ai i kēia lapaʻau kūpono ʻole a i ʻole e koi i ka noʻonoʻo kūikawā:

• ʻO ka hana iwi iwi i hoʻopilikia nui ʻia a i ʻole nā ​​helu koko haʻahaʻa loa
• Maʻi kīkī a i ʻole ka hana kīkī i hoʻopilikia nui ʻia
• Nā haʻihaʻi hou a i ʻole ka pilikia nui o nā haʻihaʻi i nā iwi e lawe ana i ke kaumaha
• Nā maʻi hana a i ʻole ka ʻōnaehana pale i nāwaliwali loa
• ʻO ka lāʻau lapaʻau radiation mua i nā wahi nui o ka iwi iwi
• Nā maʻi koko a i ʻole nā ​​pilikia koko

E nānā kāu oncologist i kāu mōʻaukala olakino piha a me nā hopena hoʻāʻo i kēia manawa ma mua o ka ʻōlelo ʻana i kēia lapaʻau. E noʻonoʻo pū lākou i kou kūlana olakino holoʻokoʻa a me ka hiki ke ʻae i nā hopena ʻaoʻao.

ʻAʻole hoʻokaʻawale wale ka makahiki iā ʻoe mai ka lapaʻau ʻana, akā e kaupaona pono kāu kauka i nā pōmaikaʻi a me nā pilikia e pili ana i kou kūlana. ʻO ke kamaʻilio hāmama e pili ana i kou mau pilikia olakino e kōkua i ka hōʻoia ʻana i nā hoʻoholo lapaʻau maikaʻi loa.

ʻO ka inoa inoa o Radium Ra 223 Dichloride

Hoʻolaha ʻia ʻo Radium Ra 223 dichloride ma lalo o ka inoa inoa Xofigo. Hana ʻia kēia lāʻau lapaʻau e Bayer HealthCare Pharmaceuticals a ʻo ia wale nō ke ʻano kūʻai o ka radium Ra 223 dichloride.

Ke loaʻa iā ʻoe kāu lapaʻau, e ʻike ʻoe iā Xofigo i helu ʻia ma kāu mau moʻolelo olakino a me nā ʻōlelo hoʻopiʻi. Hele mai ka lāʻau lapaʻau i loko o nā vials hoʻohana hoʻokahi i hoʻomākaukau ʻia no ka mahele o kēlā me kēia mea maʻi e pili ana i ko lākou kaumaha kino.

Hiki ke ʻokoʻa kāu ʻinikua ma muli o kāu hoʻolālā kikoʻī a me nā pae hoʻohālike pono olakino. Nui nā ʻoihana ʻinikua e uhi ana iā Xofigo no nā hōʻailona i ʻae ʻia, akā pono paha ka ʻae mua ma mua o ka hoʻomaka ʻana i ka lāʻau.

Nā Koho ʻē aʻe no Radium Ra 223 Dichloride

Nui nā koho lapaʻau no nā kāne me ka maʻi kanesa prostate kūʻē i ka castration a me nā metastases iwi. E kūkākūkā kāu oncologist i kēia mau koho ʻē aʻe inā ʻaʻole kūpono ka radium Ra 223 dichloride no kou kūlana.

ʻO nā lāʻau lapaʻau ʻōnaehana ʻē aʻe e komo pū ana i nā lāʻau hormone hou e like me enzalutamide a i ʻole abiraterone, hiki ke maikaʻi ʻoiai i ka maʻi kūʻē i ka castration. Hiki nō hoʻi ke noʻonoʻo ʻia nā koho chemotherapy e like me docetaxel a i ʻole cabazitaxel ma muli o kou olakino holoʻokoʻa a me ka mōʻaukala lapaʻau.

No ka mālama ʻana i ka ʻeha iwi, hiki i ka lāʻau lapaʻau radiation beam waho ke hāʻawi i ke kōkua i nā wahi ʻeha loa. ʻO nā lāʻau lapaʻau hoʻoikaika iwi e like me ka waikawa zoledronic a i ʻole denosumab e kōkua i ka pale ʻana i nā haʻi a hiki ke hōʻemi i ka ʻeha i ka wā.

E kōkua kāu hui lapaʻau iā ʻoe e hoʻomaopopo i ka hoʻohālikelike ʻana o kēia mau koho a me ka mea kūpono loa no kou kūlana kikoʻī. I kekahi manawa, ʻoi aku ka maikaʻi o nā hui pū ʻana o nā lāʻau lapaʻau ma mua o nā ala hoʻokahi.

ʻOi aku ka maikaʻi o Radium Ra 223 Dichloride ma mua o nā lāʻau lapaʻau ʻē aʻe?

Hāʻawi ʻo Radium Ra 223 dichloride i nā pono kūʻokoʻa i hoʻohālikelike ʻia me nā lāʻau lapaʻau ʻē aʻe no nā metastases iwi mai ka maʻi kanesa prostate. Ua hōʻike nā hoʻokolohua lapaʻau hiki iā ia ke hoʻolōʻihi i ke ola ʻoiai e hoʻomaikaʻi ana i ka maikaʻi o ke ola, e lilo ia i koho waiwai i ka pahu hana lapaʻau.

I ka hoʻohālikelike ʻana me ka chemotherapy, ʻo ka radium Ra 223 ke kumu maʻamau i nā hopena ʻaoʻao liʻiliʻi a me ka liʻiliʻi. Nui nā maʻi e ʻae maikaʻi iā ia ma mua o nā lāʻau chemotherapy kuʻuna, e ʻike ana i ka liʻiliʻi o ka nausea, ka nalowale o ka lauoho, a me ka luhi.

ʻO ke ala i kuhikuhi ʻia o ka lāʻau lapaʻau e hoʻokaʻawale iā ia mai ka lāʻau lapaʻau radiation waho. ʻOiai hiki i ka radiation waho ke mālama pono i nā wahi ʻeha kikoʻī, hana ka radium Ra 223 ma waena o kāu ʻōnaehana iwi, e hiki ai ke hoʻoponopono i nā metastases he nui i ka manawa like.

Eia naʻe, ʻaʻohe lāʻau lapaʻau hoʻokahi i

Inā ʻoe e hala i kahi manawa i hoʻonohonoho ʻia no ka radium Ra 223 dichloride, e kelepona koke i kāu hui oncology e hoʻonohonoho hou. Hāʻawi ʻia ka lāʻau lapaʻau ma kahi papa manawa ʻehā pule, a he mea nui ka mālama ʻana i kēia manawa no ka maikaʻi loa.

Hiki i kāu kauka ke hoʻololi iki i kāu papa hana lapaʻau e hoʻokō i ka mahele i hala, akā mai hoʻāʻo e hana i ia mea ma ka hoʻonohonoho ʻana i nā mahele kokoke. Hāʻawi ka manawa ʻehā pule i kou kino e ola ma waena o nā lāʻau lapaʻau a mālama i ka palekana.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Radium Ra 223 Dichloride?

Pono ʻoe e hoʻopau i nā mahele ʻeono i hoʻolālā ʻia o ka radium Ra 223 dichloride ke ʻole kāu kauka e hoʻoholo he mea pono ke hooki mua. Hāʻawi ka papa hana lapaʻau piha i ka pōmaikaʻi nui i hōʻike ʻia i nā hoʻokolohua lapaʻau.

Hiki i kāu oncologist ke ʻōlelo e hooki i ka lapaʻau mua inā loaʻa iā ʻoe nā hopena ʻaoʻao koʻikoʻi, inā e holomua ana kāu maʻi maʻi e pili ana i nā ʻōkana ma waho o ka iwi, a i ʻole inā e emi nui ana kou olakino holoʻokoʻa. Mai hooki i ka lapaʻau ma kāu iho me ka kūkākūkā ʻole ʻana me kāu hui mālama ola mua.

E hana anei ka Radium Ra 223 Dichloride iaʻu i ka radioactive?

ʻAe, e loaʻa iā ʻoe nā mea liʻiliʻi o ka radioactivity i loko o kou kino no hoʻokahi pule ma hope o kēlā me kēia injection. Eia naʻe, haʻahaʻa nā pae a he liʻiliʻi ka pilikia i nā poʻe ʻē aʻe ke hahai ʻoe i nā hana palekana a kāu hui mālama ola e hāʻawi ai.

ʻO nā hana maʻalahi e like me ka holoi lima ʻana, ka hoʻohana ʻana i nā hale lua kaʻawale ke hiki, a me ka pale ʻana i ka pilina pili me nā wahine hāpai a me nā keiki ʻōpio no kekahi mau lā e kōkua i ka pale ʻana i nā lālā o kou ʻohana. He manawa pōkole kēia mau hana a lilo i mea liʻiliʻi e like me ka emi ʻana o ka radioactivity.