He aha ʻo Rasagiline: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ʻo Rasagiline e kōkua i ka mālama ʻana i nā hōʻailona o ka maʻi Parkinson ma ka pale ʻana i kahi enzyme e wāwahi i ka dopamine i loko o kou lolo. Hana mālie kēia lāʻau lapaʻau akā maikaʻi i ke kāʻei hope e kōkua i ka mālama ʻana i ka dopamine e pono ai kou lolo no ka neʻe ʻana a me ka hoʻopili ʻana.

Inā ua kauoha ʻia ʻo rasagiline iā ʻoe a i ʻole kekahi āu e mālama nei, ke ʻimi nei ʻoe i ka ʻike maopopo a me ka ʻoiaʻiʻo e pili ana i ka mea e manaʻo ai. E hele kākou i nā mea a pau e pono ai ʻoe e ʻike e pili ana i kēia lāʻau lapaʻau ma ke ʻano e hiki ke mālama ʻia a hōʻoluʻolu.

He aha ʻo Rasagiline?

No ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo MAO-B inhibitors ʻo Rasagiline, ʻo ia hoʻi e pale ana i kahi enzyme kikoʻī i loko o kou lolo i kapa ʻia ʻo monoamine oxidase type B. Hoʻopau maʻamau kēia enzyme i ka dopamine, he ʻelele kemika e kōkua i ka mālama ʻana i ka neʻe a me ka hoʻopili ʻana.

Ma ka pale mālie ʻana i kēia enzyme, kōkua ʻo rasagiline i ka mālama ʻana i ka dopamine i loaʻa i loko o kou lolo. E noʻonoʻo e like me ke kōkua ʻana i kou lolo e paʻa i ka dopamine a ia e hana nei, ma mua o ka koi ʻana e hana hou.

Ua manaʻo ʻia kēia lāʻau lapaʻau he koho lapaʻau ikaika. ʻAʻole ikaika e like me levodopa, akā hāʻawi ia i ke kākoʻo paʻa a paʻa e ʻike ai ka poʻe he nui i ke kōkua no ka mālama ʻana i kā lākou mau hōʻailona.

No ke aha e hoʻohana ʻia ai ʻo Rasagiline?

Hoʻohana nui ʻia ʻo Rasagiline e mālama i ka maʻi Parkinson, ma ke ʻano he lāʻau lapaʻau kū hoʻokahi i nā pae mua a ma ke ʻano he lāʻau lapaʻau ke hoʻohana ʻia me nā lāʻau lapaʻau ʻē aʻe. Hiki i kāu kauka ke ʻōlelo iā ia inā ʻoe e ʻike nei i nā pilikia neʻe, kaʻeha, a i ʻole nā ​​haʻalulu e pili ana i ka maʻi Parkinson.

I nā pae mua o ka maʻi Parkinson, hiki i ka rasagiline ke kōkua i ka hoʻopaneʻe ʻana i ka pono no nā lāʻau lapaʻau ikaika a me ka hāʻawi ʻana i ka hōʻoluʻolu hōʻailona. Ke holomua ka maʻi Parkinson, hui pinepine ʻia me levodopa e kōkua i ka hoʻomaʻemaʻe ʻana i nā ups a me nā down e hiki ke hana me kēlā lāʻau lapaʻau.

Hoʻohana kekahi mau kauka i ka rasagiline ma waho o ka lepili no nā maʻi ʻē aʻe e pili ana i ka dopamine, ʻoiai ʻaʻole maʻamau kēia. E hoʻoholo kāu mea mālama ola inā kūpono kēia lāʻau lapaʻau no kāu kūlana.

Pehea e hana ai ʻo Rasagiline?

Hana ʻo Rasagiline ma ka pale ʻana i ka enzyme MAO-B i loko o kou lolo, nona ke kuleana no ka wāwahi ʻana i ka dopamine. Ke ālai ʻia kēia enzyme, e mau ana nā pae dopamine i ke ao.

Hana mālie a mālie kēia hana. ʻAʻole ʻoe e ʻike i ka wikiwiki koke a i ʻole ka loli nui e like me kāu e ʻike ai me kekahi mau lāʻau lapaʻau ʻē aʻe. Akā, hāʻawi ʻo rasagiline i ke kākoʻo paʻa i kūkulu ʻia i ka manawa.

Hiki nō hoʻi i ka lāʻau lapaʻau kekahi mau hopena pale i nā cell nerve, ʻoiai ke aʻo nei nā mea noiʻi i kēia pōmaikaʻi. ʻO ka mea a mākou e ʻike maopopo ai, ʻo ia ke kōkua i ka mālama ʻana i nā pae dopamine ma ke ʻano e kākoʻo ana i ka neʻe ʻana a me ka hoʻonohonoho ʻana.

Pehea wau e lawe ai i ka Rasagiline?

Lawe ʻia ʻo Rasagiline i hoʻokahi manawa i ka lā, maʻamau i ke kakahiaka me ka ʻole o ka meaʻai. ʻO ka maʻamau ka hoʻomaka ʻana o ka maʻi he 0.5 mg, hiki i kāu kauka ke hoʻonui i 1 mg i kēlā me kēia lā e pili ana i kāu pane a me nā pono.

Hiki iā ʻoe ke lawe i kēia lāʻau lapaʻau me ka wai, a ʻaʻole ia he mea nui inā ua ʻai ʻoe i kēia manawa. Eia naʻe, ʻike kekahi poʻe he maʻalahi ke hoʻomanaʻo i ka wā e lawe ai lākou me ka ʻaina kakahiaka a i ʻole kekahi hana kakahiaka maʻamau.

E hoʻāʻo e lawe i ka rasagiline i ka manawa like i kēlā me kēia lā e mālama i nā pae paʻa i kāu ʻōnaehana. Inā ʻoe e lawe ana me nā lāʻau lapaʻau Parkinson's ʻē aʻe, e hāʻawi kāu kauka i nā ʻōlelo kuhikuhi manawa kikoʻī e hoʻomaikaʻi i ka hana pū ʻana.

E ale mau i ka papa holoʻokoʻa ma mua o ka ʻoki ʻana a i ʻole ka nau ʻana. E hōʻoia kēia i ka hoʻokuʻu pono ʻana o ka lāʻau lapaʻau i kāu ʻōnaehana.

Pehea ka lōʻihi e lawe ai au i ka Rasagiline?

He lāʻau lōʻihi ka Rasagiline, a e hoʻomau ʻoe i ka lawe ʻana i kēia lāʻau no ka wā e pono ai no kou mau hōʻailona. Lawe ka hapa nui o ka poʻe me ka maʻi o Parkinson i kēia lāʻau no nā mahina a i ʻole nā makahiki, no ka mea, ua hana ʻia e hāʻawi i ke kākoʻo mau ma mua o ka hoʻoponopono wikiwiki.

E nānā kāu kauka i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau iā ʻoe i nā loiloi maʻamau. E nānā lākou i ka pane ʻana o kāu mau hōʻailona a inā paha e loaʻa ana iā ʻoe kekahi hopena ʻaoʻao e ʻoi aku ana ma mua o nā pōmaikaʻi.

Lawe kekahi poʻe i ka rasagiline no nā makahiki he nui me nā hopena maikaʻi, a ʻo nā mea ʻē aʻe paha e pono i nā hoʻoponopono i kā lākou hoʻolālā lapaʻau i ka wā e loli ai ko lākou kūlana. ʻO ke kī, ʻo ia ka mālama ʻana i ke kamaʻilio hāmama me kāu hui mālama ola e pili ana i kou manaʻo.

He aha nā hopena ʻaoʻao o Rasagiline?

E like me nā lāʻau lapaʻau a pau, hiki i ka rasagiline ke hana i nā hopena ʻaoʻao, akā nui ka poʻe e ʻae maikaʻi iā ia. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e mākaukau a hilinaʻi i kāu lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a maʻa mau e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau:

• Pōpō
• ʻEha hui a i ʻole ka ʻoʻoleʻo
• ʻAʻole maikaʻi ka ʻōpū a i ʻole ka ʻōpū
• Nā hōʻailona e like me ka maʻi flu
• Ka kaumaha a i ʻole nā loli o ke ʻano
• ʻĀwili
• Waha maloʻo

ʻAʻole pono kēia mau hopena ʻaoʻao i kēlā me kēia lā e hoʻōki i ka lāʻau lapaʻau, akā pono ʻoe e kūkākūkā iā lākou me kāu kauka inā lilo lākou i mea hoʻonāukiuki a paʻa paha.

Hiki ke loaʻa nā hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi, ʻoiai e pili ana lākou i ka liʻiliʻi o ka poʻe:

• Nā hanana koke o ka hiamoe ʻana i nā hana i kēlā me kēia lā
• Nā hallucinations a i ʻole ka huikau
• Nā hopena ʻili koʻikoʻi a i ʻole ka ʻōpala
• Nā koi a i ʻole nā ʻano hana ʻē (pāʻani, kūʻai, ʻai)
• Nā loli nui o ke koko
• ʻEha umauma a i ʻole ka puʻuwai ʻole

Inā loaʻa iā ʻoe kekahi o kēia mau hopena koʻikoʻi, e kelepona koke i kāu mea mālama ola. Hiki iā lākou ke kōkua i ka hoʻoholo ʻana inā pono e hoʻoponopono a hoʻōki ʻia paha ka lāʻau lapaʻau.

I nā manawa kakaikahi loa, hiki i ka rasagiline ke launa pū me kekahi mau meaʻai kiʻekiʻe i ka tyramine (e like me nā tīhi kahiko a i ʻole nā ʻiʻo i hoʻōla ʻia) a i ʻole nā lāʻau lapaʻau ʻē aʻe e hana i nā piʻi koko koko weliweli. E hāʻawi kāu kauka i nā alakaʻi meaʻai kikoʻī inā pono.

ʻO wai ka mea ʻaʻole pono e lawe iā Rasagiline?

ʻAʻole kūpono ʻo Rasagiline no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. Hiki i kekahi mau maʻi a me nā lāʻau lapaʻau ke hoʻolilo i ka rasagiline i palekana ʻole a i ʻole ka liʻiliʻi o ka maikaʻi.

ʻAʻole pono ʻoe e lawe iā rasagiline inā ʻoe e hoʻohana nei i kekahi mau antidepressants, ʻo ia hoʻi nā MAOI, SSRI, a i ʻole SNRIs. Hiki i ka hui pū ʻana ke hana i nā pilina weliweli e pili ana i kou koko a me ka kemika lolo.

Pono ka poʻe me ka maʻi ate koʻikoʻi e pale i ka rasagiline no ka mea e hana ana ka ate i kēia lāʻau lapaʻau. Hiki i kāu kauka ke kauoha i nā hoʻokolohua hana ate ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau e hōʻoia i ka palekana iā ʻoe.

ʻO nā lāʻau lapaʻau ʻē aʻe ʻaʻole i hui maikaʻi me ka rasagiline me:

• Meperidine (pethidine) a me nā lāʻau lapaʻau ʻeha opioid ʻē aʻe
• Dextromethorphan (loaʻa i nā lāʻau maʻi ʻaʻai)
• ʻO St. John's wort
• Tramadol
• ʻO kekahi mau antibiotics e like me linezolid

E haʻi mau i kāu kauka e pili ana i nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā huahana lāʻau lapaʻau āu e lawe nei. Aia kēia i nā lāʻau lapaʻau ma luna o ka counter i ʻike ʻia he palekana akā hiki ke launa pū me ka rasagiline.

Nā inoa inoa Rasagiline

Loaʻa ʻo Rasagiline ma lalo o ka inoa inoa Azilect, ʻo ia ka mana i kauoha pinepine ʻia. Loaʻa nō hoʻi nā mana generic o ka rasagiline a hana like me ka lāʻau lapaʻau inoa inoa.

Hiki i kāu lāʻau lapaʻau ke lawe i ka inoa inoa a i ʻole ka mana generic, ma muli o kāu ʻinikua a me nā makemake. Loaʻa i nā mea ʻelua ka mea hana like a he mea maikaʻi like.

Inā ʻoe e hoʻololi ana ma waena o nā mana inoa a me nā mana generic, a i ʻole ma waena o nā mea hana generic like ʻole, e haʻi i kāu kauka. ʻOiai he mea maʻamau, ʻike kekahi poʻe i nā ʻokoʻa liʻiliʻi i ke ʻano o ko lākou manaʻo, a hiki i kāu kauka ke kōkua i ka nānā ʻana i kāu pane.

Nā koho ʻē aʻe o Rasagiline

Hiki i kekahi mau lāʻau lapaʻau ʻē aʻe ke mālama i ka maʻi o Parkinson inā ʻaʻole kūpono ʻo rasagiline iā ʻoe a i ʻole e pau ka hana pono. Hiki i kāu kauka ke noʻonoʻo i kēia mau koho ʻē aʻe ma muli o kāu mau hōʻailona kikoʻī a me ka mōʻaukala olakino.

ʻO nā mea hoʻopaʻa MAO-B ʻē aʻe e pili ana iā selegiline, e hana like ana me rasagiline akā lawe ʻia i ʻelua manawa i ka lā. ʻOi aku ka maikaʻi o kekahi poʻe me kekahi ma mua o kekahi, ma muli o nā ʻaoʻao hopena a i ʻole nā makemake manawa.

ʻO nā agonists dopamine e like me pramipexole, ropinirole, a i ʻole rotigotine (loaʻa ma ke ʻano he pā) e hana ʻokoʻa ma ka hoʻoulu pololei ʻana i nā mea hoʻokipa dopamine. Hiki i kēia mau mea ke lilo i nā koho ʻē aʻe, ʻoi aku hoʻi i ka maʻi o Parkinson mua.

No nā hōʻailona holomua hou aku, ʻo levodopa ka lāʻau lapaʻau maʻamau. Hoʻohui pinepine ʻia me carbidopa e hōʻemi i nā hopena ʻaoʻao a hoʻomaikaʻi i ka pono. Hiki i kāu kauka ke ʻōlelo aku i kēia inā ʻaʻole lawa ka rasagiline wale nō i ka mālama ʻana i nā hōʻailona.

ʻOi aku ka maikaʻi o Rasagiline ma mua o Selegiline?

ʻO Rasagiline a me selegiline nā mea hoʻopaʻa MAO-B e hana like ana, akā he mau ʻokoʻa nui ko lākou e hiki ai ke kūpono kekahi iā ʻoe ma mua o kekahi.

Lawe ʻia ʻo Rasagiline i hoʻokahi manawa i ka lā, ʻoiai e lawe ʻia ʻo selegiline i ʻelua manawa i ka lā. Hiki i kēia ke maʻalahi ka rasagiline no ka nui o nā kānaka, ʻoiai ka poʻe e mālama nei i nā lāʻau lapaʻau he nui.

Ua ʻōlelo kekahi mau haʻawina he liʻiliʻi paha nā pilina o ka rasagiline me nā meaʻai i loaʻa ka tyramine, akā pono nā lāʻau ʻelua i ka ʻike ʻana i ka meaʻai. He mea maʻamau nō hoʻi ka rasagiline i ka hopena i ʻike mua ʻia i ka nui o nā kānaka.

Ua loaʻa ka Selegiline no ka lōʻihi a loaʻa nā ʻikepili palekana lōʻihi, kahi e makemake ai kekahi mau kauka. Eia naʻe, ʻoi aku ka liʻiliʻi o ka rasagiline i nā pilikia hiamoe no ka mea ʻaʻole ia e wāwahi ʻia i loko o nā pūhui e like me ka amphetamine.

E noʻonoʻo kāu kauka i kāu hana maʻamau i kēlā me kēia lā, nā lāʻau ʻē aʻe, a me nā makemake pilikino i ke koho ʻana ma waena o kēia mau koho. ʻAʻole maikaʻi kekahi ma mua o kekahi - pili ia i ka mea e hana maikaʻi ai no kou kūlana pilikino.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Rasagiline

He Palekana anei ka Rasagiline no ka poʻe me ka maʻi puʻuwai?

Hiki ke hoʻohana palekana ʻia ka Rasagiline i ka nui o nā kānaka me nā maʻi puʻuwai, akā pono ia i ka nānā pono ʻana. Hiki i ka lāʻau lapaʻau ke hoʻopilikia i ke koko a me ka puʻuwai, no laila e makemake kāu kauka e nānā pono i kāu mōʻaukala cardiac.

Inā loaʻa iā ʻoe ka maʻi puʻuwai i mālama maikaʻi ʻia, hiki nō paha ka rasagiline me ka mālama olakino kūpono. Hiki i kāu kauka ke ʻōlelo aku i nā loiloi pinepine a i ʻole ka nānā ʻana i ka puʻuwai ke hoʻomaka ʻoe i ka lāʻau.

Pono paha ka poʻe me ke koko kiʻekiʻe ʻole a i ʻole nā ​​puʻuwai i hala koke aku nei e pale i ka rasagiline a i ʻole e hoʻohana me ka akahele loa. E kūkākūkā mau i kāu mōʻaukala cardiac piha me kāu mea mālama ola ma mua o ka hoʻomaka ʻana i kekahi lāʻau lapaʻau hou.

He aha kaʻu e hana ai inā ua lawe hewa au i ka nui o ka Rasagiline?

Inā ua lawe hewa ʻoe i ka nui o ka rasagiline ma mua o ka mea i kauoha ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena hoʻomalu i ka lāʻau make. ʻO ka lawe ʻana i ka nui hiki ke hoʻoulu i nā loli koko weliweli, nā poʻo nui, a i ʻole nā ​​hōʻailona koʻikoʻi ʻē aʻe.

Mai kali e ʻike inā e ulu ana nā hōʻailona – e kiʻi i ka ʻōlelo aʻoaʻo lapaʻau koke. ʻO ka loaʻa ʻana o ka hue lāʻau me ʻoe hiki ke kōkua i nā mea mālama ola e hoʻoholo pololei i ka nui o kāu i lawe ai a hāʻawi i ka lāʻau kūpono.

No ka pale ʻana i ka overdoses ulia pōpilikia, e noʻonoʻo e hoʻohana i kahi mea hoʻonohonoho pila a i ʻole e hoʻonohonoho i nā mea hoʻomanaʻo kelepona. Inā ʻoe e mālama ana i kekahi me nā pilikia hoʻomanaʻo, e kōkua iā lākou e hoʻokumu i kahi hana lāʻau palekana.

He aha kaʻu e hana ai inā e poina iaʻu kahi mahele o Rasagiline?

Inā poina iā ʻoe kahi mahele o rasagiline, e lawe koke iā ia ke hoʻomanaʻo ʻoe, ke ʻole kokoke ka manawa no kāu mahele i hoʻonohonoho ʻia e hiki mai ana. I kēlā hihia, e lele i ka mahele i poina a hoʻomau me kāu papa manawa maʻamau.

Mai lawe i ʻelua mahele i ka manawa hoʻokahi e hoʻoponopono ai i kahi mahele i poina. Hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao me ka hāʻawi ʻole ʻana i ka pōmaikaʻi hou.

Inā poina pinepine ʻoe i nā mahele, e hoʻāʻo e hoʻopili i kāu lāʻau i kahi hana maʻamau i kēlā me kēia lā e like me ka palaki ʻana i kou mau niho a i ʻole ka ʻai ʻana i ka ʻaina kakahiaka. Kōkua ka kūlike i ka mālama ʻana i nā pae paʻa o ka lāʻau i loko o kāu ʻōnaehana.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Rasagiline?

Pono ʻoe e hooki i ka lawe ʻana iā rasagiline ma lalo o ke alakaʻi a kāu kauka. ʻAʻole e hoʻokumu ka hooki ʻana i nā hōʻailona haʻalele weliweli, akā e hoʻi hou paha kāu mau hōʻailona Parkinson a i ʻole e ʻino me ka ʻole o ke kākoʻo o ka lāʻau.

Hiki i kāu kauka ke ʻōlelo e hooki i ka rasagiline inā e ʻike ana ʻoe i nā hopena ʻaoʻao nui, inā ʻaʻole ia e kōkua hou ana i kāu mau hōʻailona, a i ʻole inā e hoʻololi ana ʻoe i kahi ala lapaʻau ʻokoʻa.

Hiki i kekahi poʻe ke hōʻemi mālie i kā lākou mahele ma mua o ka hooki ʻana, a ʻo nā mea ʻē aʻe e hiki ke hooki koke ʻia e pili ana i ka ʻōlelo a kā lākou kauka. ʻO ke kī ka loaʻa ʻana o kahi hoʻolālā e mālama i kāu mau hōʻailona i ka wā o ka hoʻololi.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Rasagiline?

He kūpono ka inu ʻana i ka waiʻona maʻalahi i ka wā e lawe ana i ka rasagiline, akā pono ʻoe e kūkākūkā mua me kāu kauka. Hiki i ka waiʻona ke launa pū me ka lāʻau a me nā hōʻailona o ka maʻi Parkinson ma nā ʻano like ʻole mai kēlā kanaka i kēia kanaka.

ʻIke kekahi poʻe e hoʻonui ka waiʻona i kā lākou mau hōʻailona neʻe a i ʻole e hoʻonui i ka ʻūlū ke hui pū ʻia me ka rasagiline. Hiki i nā mea ʻē aʻe ke ʻike ua loli ko lākou ʻae ʻana i ka waiʻona maʻamau mai ka hoʻomaka ʻana i ka lāʻau.

Inā ʻae kāu kauka i ka hoʻohana ʻana i ka waiʻona i kekahi manawa, e hoʻomaka me nā mea liʻiliʻi e ʻike pehea e pane ai kou kino. E hoʻokau mau i kou palekana a pale i ka waiʻona inā ʻike ʻoe i nā pilina e pili ana a i ʻole nā hōʻailona i hoʻonui ʻia.