He aha ʻo Remimazolam: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Remimazolam he lāʻau lapaʻau hoʻomaha pōkole e hoʻohana ai nā kauka i ka wā o nā kaʻina hana lapaʻau e kōkua iā ʻoe e hoʻomaha a noho mālie. No ka papa o nā lāʻau lapaʻau i kapa ʻia ʻo benzodiazepines, e hana ana ma ka hoʻolohi ʻana i ka hana o ka lolo e hana i kahi mokuʻāina maluhia a hiamoe.

Hāʻawi ʻia kēia lāʻau lapaʻau ma o ka laina IV (intravenous) pololei i loko o kou kahe koko. ʻO ka mea e hana ai ʻo remimazolam he mea kūikawā i ka wikiwiki o kāna hana a me ka wikiwiki o kou kino e hoʻomaʻemaʻe iā ia, e kūpono ana no nā kaʻina hana pōkole kahi e pono ai ʻoe e ala aʻe me ka ʻike.

He aha ʻo Remimazolam?

ʻO Remimazolam kahi ʻano hou o ka benzodiazepine i hoʻolālā ʻia no ka hoʻomaha ʻana i ka lāʻau lapaʻau. ʻAʻole like me nā mea hoʻomaha kahiko e hiki ke noho i loko o kāu ʻōnaehana no nā hola, ua wāwahi koke kēia lāʻau lapaʻau i loko o kou kino ma o nā kaʻina hana maoli.

Hana ka lāʻau ma ka hoʻonui ʻana i kahi kemika lolo i kapa ʻia ʻo GABA, e hana ana e like me ka hōʻailona

Hoʻohana kekahi mau halemai i ka remimazolam i nā keʻena mālama koʻikoʻi no nā maʻi e pono ai ka hoʻomaha manawa pōkole i ka wā e hoʻohana ana i nā mīkini hanu. ʻO ka manawa hoʻōla wikiwiki e maʻalahi ai i nā kauka ke loiloi i ke ʻano o nā maʻi.

Pehea e hana ai ʻo Remimazolam?

Ua manaʻo ʻia ʻo Remimazolam he lāʻau hoʻomaha ikaika waena e hana ana ma ka ʻimi ʻana i nā mea hoʻokipa kikoʻī i kou lolo. Hoʻonui ia i nā hopena o GABA, kahi neurotransmitter e hoʻolohi maoli i ka hana lolo a hoʻolaha i ka hoʻomaha.

Ke komo ka lāʻau lapaʻau i kou kahe koko, hiki i kou lolo i loko o kekahi mau minuke. Hoʻomaka ka hopena hoʻomaha maʻamau i loko o 1-3 mau minuke o ka lawelawe ʻana, e hōʻoluʻolu iā ʻoe a hoʻomaha me ka nalowale ʻole o ka ʻike.

ʻO ka mea e hoʻokaʻawale ai i ka remimazolam ʻo ke ʻano o kou kino e hana ai. Hoʻokaʻawale nā enzymes kūikawā i ka lāʻau lapaʻau me ka wikiwiki, maʻamau i loko o 30-60 mau minuke. ʻO kēia wāwahi wikiwiki ʻana, ʻo ia hoʻi, ʻaʻole nui nā hopena e hoʻomau ana i ka hoʻohālikelike ʻana i nā mea hoʻomaha ʻē aʻe e hiki ke hoʻoluhi iā ʻoe no nā hola.

Pehea wau e lawe ai iā Remimazolam?

ʻAʻole ʻoe e lawe iā remimazolam iā ʻoe iho - hāʻawi mau ʻia e nā poʻe loea mālama ola i hoʻomaʻamaʻa ʻia i kahi hoʻonohonoho lāʻau. He wai maopopo ka lāʻau lapaʻau i hui pū ʻia me ka saline a hāʻawi ʻia ma o ka laina IV i kou lima.

Ma mua o kāu kaʻina hana, e hoʻokomo kāu hui lapaʻau i kahi paipu plastik liʻiliʻi (IV catheter) i loko o kahi vein i kou lima a i ʻole ka lima. A laila e hoʻokomo mālie lākou i ka remimazolam ma o kēia laina i ka wā e nānā ana i kou hanu, ka puʻuwai, a me ke koko.

E hoʻoponopono kāu kauka i ka nui ma muli o kou makahiki, ke kaumaha, ka mōʻaukala olakino, a me ke ʻano o kou pane ʻana i ka lāʻau lapaʻau. Pono ka hapa nui o nā kānaka i nā mea liʻiliʻi loa - maʻamau i kekahi mau milligrams - e hoʻokō i ka pae kūpono o ka hoʻomaha.

Pono ʻoe e pale i ka ʻai ʻana a i ʻole ka inu ʻana no kekahi mau hola ma mua o kāu kaʻina hana, e like me ke kuhikuhi ʻana e kāu hui lapaʻau. Kōkua kēia manawa hoʻokēʻai i ka pale ʻana i nā pilikia a hōʻoia i ka hana pono o ka lāʻau lapaʻau.

Pehea ka lōʻihi e lawe ai au i ka Remimazolam?

Hoʻohana ʻia ka Remimazolam no nā manawa pōkole i ka wā o nā kaʻina hana lapaʻau, maʻamau mai 15 mau minuke a i kekahi mau hola. Aia ka lōʻihi i ka lōʻihi o ka pau ʻana o kāu kaʻina hana.

E hoʻomau ana kāu mea mālama ola kino i ka hāʻawi ʻana iā ʻoe i nā mea liʻiliʻi i ka wā o ke kaʻina hana e like me ka mea e pono ai e mālama i kou pae hōʻoluʻolu. E hooki lākou i ka lāʻau lapaʻau ke pau ke kaʻina hana, a e hoʻomaka ʻoe e ala i luna i loko o kekahi mau minuke.

ʻAʻole like me nā lāʻau lapaʻau āu e lawe ai ma ka home, ʻaʻole i manaʻo ʻia ka remimazolam no ka hoʻohana mau ʻana. I kēlā me kēia manawa e pono ai ʻoe i ka sedation no kahi kaʻina hana, e mālama kāu hui lapaʻau iā ia ma ke ʻano he hoʻomaka hou, e hoʻoponopono ana i ka mahele ma muli o kou kūlana olakino o kēia manawa.

He aha nā hopena ʻaoʻao o ka Remimazolam?

E like me nā lāʻau lapaʻau a pau, hiki i ka remimazolam ke hana i nā hopena ʻaoʻao, ʻoiai ka hapa nui o nā kānaka e ʻae maikaʻi iā ia ke hāʻawi ʻia e nā mea mālama ola kino i ʻike ʻia. ʻO nā hopena maʻamau ka ʻāpana o ka hana ʻana o ka lāʻau lapaʻau - ka hiamoe a me nā hakahaka hoʻomanaʻo manawa pōkole a puni ke kaʻina hana.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike:

• Hiamoe e hiki ke mau i 1-2 mau hola ma hope o ke kaʻina hana
• Ka nalowale ʻana o ka hoʻomanaʻo manawa pōkole i ka manawa o ke kaʻina hana
• ʻO ka ʻūlū māmā a i ʻole ka manaʻo ʻole
• Nausea a i ʻole ka ʻōpū
• ʻEha ke poʻo
• Ke manaʻo huikau a i ʻole disoriented i ka wā e ala mua ai

He maʻalahi kēia mau hopena a hoʻoponopono iā lākou iho i ka wā e haʻalele ai ka lāʻau lapaʻau i kāu ʻōnaehana. ʻO ka loaʻa ʻana o kekahi e hoʻokele iā ʻoe i ka home a noho pū me ʻoe no kekahi mau hola e kōkua i ka hōʻoia ʻana i kou palekana i ka wā e ola ai.

He kakaikahi nā hopena ʻaoʻao koʻikoʻi akā hiki ke komo i nā pilikia hanu, nā loli koko, a i ʻole nā ​​hopena maʻi. Mālama kāu hui lapaʻau iā ʻoe i ka wā a ma hope o ke kaʻina hana e nānā i nā hōʻailona e pili ana.

I nā hihia kakaʻikahi loa, hiki i kekahi poʻe ke ʻike i nā hopena paradoxical kahi e lilo ai lākou i mea ʻeha a hopohopo paha ma kahi o ka mālie. Inā hiki kēia, hiki i kāu mea mālama ola ke hoʻohuli koke i nā hopena me kekahi lāʻau ʻē aʻe.

ʻO wai ka mea pono ʻole e lawe iā Remimazolam?

ʻAʻole kūpono ʻo Remimazolam no nā mea a pau, a e nānā pono kāu hui lapaʻau i kāu mōʻaukala olakino ma mua o ka hoʻohana ʻana i kēia lāʻau. ʻO ka poʻe me nā pilikia hanu nui, kekahi mau maʻi puʻuwai, a i ʻole nā maʻi maʻi i nā benzodiazepines e pono maʻamau i nā ʻano hana sedation ʻē aʻe.

E makaʻala loa kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau maʻi:

• Maʻi māmā nui a i ʻole nā pilikia hanu
• ʻApeke hiamoe ʻaʻole i mālama pono ʻia
• Maʻi ate a i ʻole maʻi kīkī nui
• Mōʻaukala o ka lāʻau a i ʻole ka waiʻona
• Myasthenia gravis (he maʻi nāwaliwali ʻiʻo)
• Nā pilikia puʻuwai nui
• ʻIke ʻia ka maʻi maʻi i nā benzodiazepines

Pono nā wahine hāpai a me nā makuahine e hānai ana i ka umauma i ka noʻonoʻo kūikawā, no ka mea, hiki i ka lāʻau lapaʻau ke hele i ka placenta a ʻike ʻia i ka waiū umauma. E kaupaona kāu mea mālama ola i nā pōmaikaʻi e kūʻē i nā pilikia hiki ke loaʻa i kēia mau kūlana.

Hiki i nā mākua ʻelemakule ke ʻoi aku ka naʻau i nā hopena o remimazolam a loaʻa maʻamau i nā mea haʻahaʻa. Hiki nō hoʻi i ka lāʻau lapaʻau ke launa pū me nā lāʻau ʻē aʻe, no laila e hōʻoia e haʻi i kāu hui lapaʻau e pili ana i nā lāʻau lapaʻau a pau, nā mea hoʻohui, a me nā lāʻau lapaʻau lāʻau āu e lawe nei.

Nā inoa inoa Remimazolam

Loaʻa ʻo Remimazolam ma lalo o ka inoa inoa ʻo Byfavo ma ʻAmelika Hui Pū ʻIa a me nā ʻāina ʻē aʻe. ʻO kēia ka inoa inoa mua āu e hālāwai ai i ka hapa nui o nā hoʻonohonoho lapaʻau.

I kekahi mau wahi, hiki iā ʻoe ke ʻike iā ia i kūʻai ʻia ma lalo o nā inoa like ʻole, akā ʻo ka mea hana e mau ana. E ʻike kāu mea mālama ola i ka lāʻau lapaʻau ma kona inoa generic (remimazolam) me ka nānā ʻole i ka inoa inoa i hoʻohana ʻia ma kā lākou keʻena.

Mai ka wā he lāʻau lapaʻau hou kēia, i ʻae ʻia e ka FDA i ka makahiki 2020, ʻaʻole i loaʻa nā ʻano generic i kēia manawa. Mai ka mea hana mua mai nā remimazolam a pau i kēia manawa.

Nā koho ʻē aʻe no Remimazolam

Inā ʻaʻole kūpono ka remimazolam iā ʻoe, aia kekahi mau koho sedation ʻē aʻe e pili ana i kāu mau pono a me ka mōʻaukala olakino. Hiki i kāu mea mālama ola ke koho mai nā koho ʻē aʻe e hana ʻokoʻa akā e loaʻa nā hopena like.

ʻO nā koho ʻē aʻe maʻamau:

• Midazolam - kekahi benzodiazepine i hoʻohana ʻia no nā makahiki he nui
• Propofol - he ʻano sedative ʻē aʻe e hana wikiwiki ana
• Dexmedetomidine - he lāʻau lapaʻau e hāʻawi ana i ka sedation me ka hoʻopilikia ʻole i ka hanu
• Ketamine - i kekahi manawa hoʻohana ʻia no nā kaʻina hana e koi ana i ka sedation hohonu
• Nitrous oxide - "ke kinoea ʻakaʻaka" no nā pono sedation māmā

Loaʻa i kēlā me kēia koho ʻē aʻe kāna mau pōmaikaʻi a me nā mea e pono ai. E koho kāu anesthesiologist a i ʻole ka hui kaʻina hana i ke koho maikaʻi loa e pili ana i kāu mōʻaukala olakino, ke ʻano o ke kaʻina hana, a me ka lōʻihi o ka manawa e pono ai.

Ke hilinaʻi pinepine nei ke koho i nā mea e like me kou makahiki, nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, a inā paha he mau maʻi olakino e hana ai i hoʻokahi koho palekana ma mua o nā mea ʻē aʻe.

ʻOi aku ka maikaʻi o Remimazolam ma mua o Midazolam?

ʻO Remimazolam a me midazolam nā benzodiazepines i hoʻohana ʻia no ka sedation, akā he mau ʻokoʻa nui ko lākou e kūpono ai kēlā me kēia no nā kūlana like ʻole. ʻAʻole ʻoi aku ka maikaʻi o kekahi - pili ia i kāu mau pono a me nā kūlana.

ʻO ka pōmaikaʻi nui o Remimazolam ʻo ia ka manawa hoʻōla wikiwiki a hiki ke wānana. No ka mea e wāwahi wikiwiki kou kino iā ia ma o nā kaʻina hana enzyme maoli, e ʻoi aku ka makaʻala ma hope o kāu kaʻina hana i hoʻohālikelike ʻia me midazolam.

Ua hoʻohana palekana ʻia ʻo Midazolam no nā makahiki he nui a ʻoi aku ke kumu kūʻai. Akā naʻe, hiki iā ia ke hōʻiliʻili i loko o kou ʻōnaehana, ʻoi aku ka nui inā ʻoe i ʻelemakule a i ʻole he pilikia o ke ake, e alakaʻi ana i nā manawa hoʻōla lōʻihi a me ka hiamoe lōʻihi.

No nā kaʻina hana outpatient kahi e pono ai ʻoe e hele i ka home i ka lā hoʻokahi, hiki i ka hoʻomaʻemaʻe wikiwiki ʻana o remimazolam ke lilo i mea maikaʻi loa. No nā kaʻina hana lōʻihi a i ʻole ke kumu kūʻai nui, ʻo midazolam paha ke koho maikaʻi.

Nā Nīnau i Nīnau pinepine ʻia e pili ana iā Remimazolam

Ua palekana ʻo Remimazolam no ka poʻe me ka maʻi puʻuwai?

Hiki ke hoʻohana palekana ʻia ʻo Remimazolam i nā poʻe he nui me ka maʻi puʻuwai, akā pono kāu cardiologist a me ka hui anesthesia e hana pū e hōʻoia he koho kūpono ia nāu. ʻO ka maʻamau, hoʻoulu ka lāʻau i nā loli liʻiliʻi i ke koko a me ka helu o ka puʻuwai i hoʻohālikelike ʻia me kekahi mau sedatives ʻē aʻe.

E nānā kāu hui lapaʻau i kāu puʻuwai a me ke koko i ka wā o ke kaʻina hana. E nānā pū lākou i kāu maʻi puʻuwai kikoʻī, nā lāʻau lapaʻau i kēia manawa, a me ke kūlana olakino holoʻokoʻa ma mua o ka hoʻoholo ʻana inā kūpono ʻo remimazolam.

Pono paha ka poʻe me ka maʻi puʻuwai koʻikoʻi a i ʻole nā puʻuwai puʻuwai paʻa ʻole i nā ʻano hana sedation ʻē aʻe. E koho mau kāu poʻe mālama ola i ke koho palekana loa no kāu kūlana pilikino.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Remimazolam?

ʻAʻole pono ʻoe e hopohopo e pili ana i ka loaʻa ʻana o ka nui o remimazolam no ka mea e mālama nā poʻe loea mālama ola i nā mea a pau o kāu hoʻokele lāʻau. E nānā lākou i kāu pane i nā manawa a pau a hoʻoponopono i ka mahele e like me ka mea e pono ai i kāu kaʻina hana.

Inā loaʻa iā ʻoe ka nui ma mua o ka mea i manaʻo ʻia, loaʻa i kāu hui lapaʻau nā ala he nui e kōkua iā ʻoe e ola palekana. Hiki iā lākou ke hāʻawi iā ʻoe i kahi lāʻau i kapa ʻia ʻo flumazenil e hoʻohuli koke i nā hopena o remimazolam, e kōkua ana iā ʻoe e ala wikiwiki.

Ua aʻo ʻia kāu poʻe mālama ola e ʻike i nā hōʻailona o ka over-sedation a pane koke. E kākoʻo lākou i kou hanu inā pono a nānā pono i kou mau hōʻailona ola a hiki i kou ala piha ʻana a paʻa.

He aha kaʻu e hana ai inā e hala wau i kahi mahele o Remimazolam?

ʻAʻole pili kēia nīnau i ka remimazolam no ka mea ʻaʻole ia he lāʻau lapaʻau āu e lawe ai ma ka home ma kahi papa manawa. Hāʻawi wale nā ​​poʻe loea mālama ola i ka remimazolam i ka wā o nā kaʻina hana lapaʻau i nā wahi lapaʻau i mālama ʻia.

Inā he kaʻina hana i hoʻonohonoho ʻia e pono ai ka sedation a e hala ʻoe i kāu manawa, pono ʻoe e hoʻonohonoho hou me kāu mea mālama ola. E hāʻawi lākou iā ʻoe i ka lāʻau lapaʻau hou i ka wā o kāu kaʻina hana i hoʻonohonoho hou ʻia.

I kēlā me kēia manawa e pono ai ʻoe i ka sedation, mālama kāu hui lapaʻau iā ia ma ke ʻano he kūlana hou, e loiloi pono ana i kou kūlana olakino i kēia manawa a hoʻoponopono i ka lāʻau lapaʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Remimazolam?

ʻAʻole pono ʻoe e hana i nā hoʻoholo e pili ana i ka hooki ʻana i ka remimazolam no ka mea e kāohi ana kāu hui mālama ola i ka wā e hoʻomaka ai a hooki i ka lāʻau lapaʻau i ka wā o kāu kaʻina hana. E hooki lākou iā ia ke pau kāu kaʻina hana.

E hoʻomaʻemaʻe maoli ka lāʻau lapaʻau mai kāu ʻōnaehana i loko o 30-60 mau minuke ma hope o ka hooki ʻana o kāu mea mālama ola iā ia. E ala mālie ʻoe i ka wā e haʻalele ai ka lāʻau i kou kino.

Ke alakaʻi ʻia nei kāu hana hoʻōla e kāu hui lapaʻau, nāna e nānā iā ʻoe a hiki i kou ala ʻana e hele palekana i ka home. E hōʻike lākou iā ʻoe i ka wā e mākaukau ai ʻoe e haʻalele a me ka mea e manaʻo ai i ka wā o kāu hoʻōla ʻana ma ka home.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o Remimazolam?

ʻAʻole pono ʻoe e kalaiwa a i ʻole e hana i nā mīkini no ka liʻiliʻi o 24 mau hola ma hope o ka loaʻa ʻana o ka remimazolam, ʻoiai paha e manaʻo ʻoe e ala koke. Hiki i ka lāʻau lapaʻau ke hoʻopilikia i kou manawa pane a me ka hoʻokolokolo ʻana ma nā ʻano maʻalahi ʻaʻole paha ʻoe e ʻike.

E hoʻolālā e loaʻa i kekahi e hoʻokele iā ʻoe i ka home ma hope o kāu kaʻina hana a noho pū me ʻoe no kekahi mau hola. ʻAʻole he hana palekana wale nō kēia - he koi palekana ia e hoʻokō ʻia e ka hapa nui o nā keʻena lapaʻau ma mua o ka ʻae ʻana iā ʻoe e haʻalele.

ʻOiai inā manaʻo ʻoe he maʻamau loa, ke hana nei nō kou lolo i nā hopena o ka lāʻau lapaʻau. ʻO nā hana e koi ana i nā reflexes wikiwiki a i ʻole ka hoʻoholo ʻana i nā hoʻoholo nui e kali a hiki i ka lā aʻe ke hoʻi piha ʻoe i ka pae kumu.