He aha ʻo Rilonacept: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ʻo Rilonacept e kōkua i ka hoʻomaha ʻana i kāu ʻōnaehana pale ke hana nui. Hana ia ma ka pale ʻana i kekahi mau protein i kapa ʻia ʻo interleukins e hoʻoulu ai i ka mumū i loko o kou kino, ʻo ia hoʻi ka interleukin-1 beta a me ka interleukin-1 alpha.

E noʻonoʻo iā rilonacept ma ke ʻano he pale kūikawā e komo i ka wā e hoʻomaka ai ka ʻōnaehana pale o kou kino e hoʻouka i nā ʻiʻo olakino. Hāʻawi ʻia kēia lāʻau lapaʻau ma ke ʻano he injection ma lalo o kou ʻili, a ua hoʻolālā ʻia e kōkua i ka poʻe me nā maʻi mumū laha ʻole e ola ʻoluʻolu.

No ke aha e hoʻohana ʻia ai ʻo Rilonacept?

Hoʻomaʻamaʻa ʻo Rilonacept i nā maʻi mumū laha ʻole kahi e hoʻouka hewa ai kāu ʻōnaehana pale i kou kino ponoʻī. Ua ʻae mua ʻia ka lāʻau lapaʻau no nā maʻi periodic i pili i ka cryopyrin (CAPS), kahi hui o nā maʻi genetic e hoʻoulu ai i ke kuni a me ka mumū.

Hiki i kāu kauka ke kauoha iā rilonacept inā loaʻa iā ʻoe nā maʻi e like me ka maʻi autoinflammatory anu o ka ʻohana, ka maʻi Muckle-Wells, a i ʻole ka maʻi mumū multisystem neonatal-onset. Loaʻa i kēia mau maʻi nā hōʻailona like me ke kuni periodic, ka ʻeha hui, nā ʻili ʻili, a i kekahi manawa nā pilikia koʻikoʻi e pili ana i kou mau maka, ka lohe, a i ʻole nā ​​puʻupaʻa.

Hana maikaʻi ka lāʻau lapaʻau no ka poʻe i hōʻoia i nā loli genetic e hoʻoulu ai i kēia mau maʻi mumū. E hana paha kāu mea mālama ola i nā hoʻokolohua genetic kikoʻī ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau e hōʻoia i ka kūpono o rilonacept no kāu maʻi.

Pehea e hana ai ʻo Rilonacept?

Hana ʻo Rilonacept ma ka ʻimi ʻana a me ka pale ʻana i ka interleukin-1, kahi protein e hoʻoulu ai i ka mumū i loko o kou kino. Ke loaʻa iā ʻoe kekahi mau maʻi genetic, hana kou mau cell i ka nui o kēia protein mumū, e hoʻoulu ana i nā hōʻailona ʻeha āu e ʻike ai.

He hana kēia lāʻau lapaʻau e like me ka mea hoʻopunipuni e hopu ana i ka interleukin-1 keu ma mua o ka hiki iā ia ke hana i ka mumū. Ma ka hoʻēmi ʻana i kēia hōʻailona mumū, kōkua ʻo rilonacept i ka pale ʻana i nā hanana kuni, nā ʻeha hui, a me nā pilikia ʻili e hele pū me kēia mau maʻi laha.

Ua manaʻo ʻia ʻo Rilonacept he lāʻau lapaʻau i manaʻo ʻia, ʻo ia hoʻi e kamaʻilio kūikawā ana i ke kumu kumu o ka mumū ma mua o ka hūnā ʻana i nā hōʻailona. ʻO kēia ka mea e pono ai no nā maʻi e mālama ai, ʻoiai ua hoʻolālā ʻia no nā ala mumū kikoʻī loa.

Pehea e lawe ai au i ka Rilonacept?

Hele mai ʻo Rilonacept ma ke ʻano he pauka e hui pū ai kāu mea mālama ola a i ʻole ʻoe me ka wai maʻemaʻe e hana i kahi injection. Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano he injection subcutaneous, ʻo ia hoʻi e hele ana i loko o ka ʻiʻo momona ma lalo pono o kou ʻili, e like me ke ʻano o ka poʻe me ka maʻi diabetes e hāʻawi iā lākou iho i ka insulin.

E hoʻomaka maʻamau kāu kauka iā ʻoe me kahi mahele hoʻouka i kou lā mua, a laila e hahai ʻia e nā mahele mālama i kēlā me kēia pule. Aia ka nui o ka nui i kou kaumaha a me kou kūlana kikoʻī. Loaʻa ka hapa nui o nā kānaka i kā lākou injections ma nā wahi e like me ka ʻūhā, ka lima luna, a i ʻole ka ʻōpū, e hoʻololi ana i nā wahi injection e pale ai i ka huhū.

Hiki iā ʻoe ke lawe i ka rilonacept me ka ʻole o ka meaʻai no ka mea he injection ia ma mua o ka pill. Eia naʻe, pono ʻoe e mālama i ka lāʻau lapaʻau i loko o kāu pahu hau a e ʻae iā ia e hiki i ka mahana o ka lumi ma mua o ka hui ʻana a me ka hoʻokomo ʻana. E aʻo kāu hui mālama ola iā ʻoe i ke ʻano injection kūpono inā e hāʻawi ana ʻoe iā ʻoe iho i nā pana ma ka home.

E hoʻohana mau i nā lima maʻemaʻe a me ke ʻano maʻemaʻe i ka wā e hoʻomākaukau ai i kāu injection. Pono e hoʻohana ʻia ka lāʻau lapaʻau i hui ʻia i loko o ʻekolu hola o ka hoʻomākaukau ʻana a pono e nānā maopopo a me ka ʻole o ke kala ke hui pono ʻia.

Pehea ka lōʻihi e lawe ai au i ka Rilonacept?

Pono ka hapa nui o nā kānaka me nā maʻi maʻi e pili ana i ka cryopyrin e lawe i ka rilonacept no ka manawa lōʻihi e mālama ai i kā lākou mau hōʻailona. Ma muli o kēia mau maʻi genetic, ʻaʻole e pau ke kumu kumu, no laila pono ka mālama ʻana i ka wā e mālama ai i ka hōʻoluʻolu o nā hōʻailona.

E hoʻomaka ana ʻoe e ʻike i nā hoʻomaikaʻi ʻana i kāu mau hōʻailona i loko o nā pule mua o ka mālama ʻana. Nui ka poʻe e ʻike i ka emi nui ʻana o nā hanana kuni, nā ʻeha hui, a me nā ʻōpala ʻili i kēia manawa. Eia naʻe, hiki ke lawe i kekahi mau mahina e ʻike i nā pōmaikaʻi piha o ka lāʻau.

E nānā kāu kauka i kāu pane ʻana i ka mālama ʻana a hiki ke hoʻoponopono i kāu mahele a i ʻole ke alapine e pili ana i ka maikaʻi o ka mālama ʻana i kāu mau hōʻailona. Pono paha kekahi poʻe e hoʻonui i ka mahele i ka manawa, ʻoiai ʻo nā mea ʻē aʻe e ʻike i kā lākou mau hōʻailona i mālama maikaʻi ʻia me ka mahele mua.

Mai hooki i ka lawe ʻana i ka rilonacept me ka ʻole e kamaʻilio mua me kāu mea mālama ola. E hoʻi hou ana kāu mau hōʻailona inā ʻoe e hoʻōki i ka lāʻau, a makemake paha kāu kauka e hōʻemi mālie i kāu mahele a i ʻole e hoʻololi iā ʻoe i kahi lapaʻau ʻē aʻe.

He aha nā hopena ʻaoʻao o Rilonacept?

E like me nā lāʻau lapaʻau a pau, hiki i ka rilonacept ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole nā ​​mea a pau e ʻike iā lākou. ʻO nā hopena ʻaoʻao maʻamau e maʻalahi a hiki ke mālama ʻia, ʻoiai ʻo nā hopena ʻaoʻao koʻikoʻi ʻaʻole pinepine akā pono ka lāʻau lapaʻau koke.

Eia nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike i ka wā e hoʻoponopono ai kou kino i ka lāʻau:

• Nā hopena ma ka pūnaewele injection e like me ka ʻulaʻula, ka pehu, a i ʻole ka ʻeha māmā
• Nā maʻi maʻi hanu luna e like me ke anu a i ʻole nā ​​maʻi sinus
• Nā poʻo e hiki ke hana i ka wā e hoʻomaka ai i ka mālama ʻana
• Nausea a i ʻole ka ʻoluʻolu o ka ʻōpū
• ʻEha ʻiʻo a i ʻole nā ​​hui
• Luhi a i ʻole ka manaʻo e luhi ma mua o ka maʻamau

Hiki ke maikaʻi pinepine kēia mau hopena ʻaoʻao maʻamau i ka wā e maʻa ai kou kino i ka lāʻau. ʻO ka hapa nui o nā hopena ma kahi o ka injection he mea manawa wale nō a hiki ke mālama ʻia me ka hau a i ʻole nā mea hōʻoluʻolu ʻeha.

Pono nā hopena ʻaoʻao koʻikoʻi i ka lāʻau lapaʻau koke, ʻoiai e hana pinepine ʻia lākou:

• Nā maʻi koʻikoʻi e hiki ke ulu no ka mea e kāohi ana ka lāʻau i kou ʻōnaehana pale
• Nā hopena maʻi maʻi koʻikoʻi me ka pilikia o ka hanu ʻana, ka pehu ʻana o ka maka a i ʻole ka ʻāʻī
• ʻO ka ʻeha ʻole a i ʻole ke kahe ʻana
• Ka wela mau a i ʻole nā ​​hōʻailona e like me ka maʻi flu
• ʻO ka ʻeha nui o ka ʻōpū a i ʻole ka nausea mau

No ka mea e pili ana ka rilonacept i kāu ʻōnaehana pale, hiki iā ʻoe ke maʻalahi i nā maʻi. E kelepona koke i kāu kauka inā loaʻa iā ʻoe nā hōʻailona o ka maʻi e like me ke kuni, nā anu, a i ʻole ka ʻū mau.

ʻO kekahi mau hopena ʻaoʻao laha akā koʻikoʻi e pili ana i ka piʻi ʻana o ka pilikia o kekahi mau maʻi maʻi, ʻoiai me he mea lā ʻaʻole maʻamau kēia me ka rilonacept i hoʻohālikelike ʻia me kekahi mau lāʻau lapaʻau e kāohi ana i ka pale. E nānā mau kāu kauka iā ʻoe no nā loli e pili ana.

ʻO wai ka mea ʻaʻole pono e lawe iā Rilonacept?

ʻAʻole kūpono ʻo Rilonacept no nā mea a pau, a ʻo kekahi mau maʻi lapaʻau a i ʻole nā ​​kūlana e palekana ʻole ai ka hoʻohana ʻana. E nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana i kēia lāʻau.

ʻAʻole pono ʻoe e lawe i ka rilonacept inā loaʻa iā ʻoe kahi maʻi ikaika a koʻikoʻi ma nā wahi a pau o kou kino. Aia kēia me nā maʻi bacteria, viral, fungal, a i ʻole parasitic i mālama ʻole ʻia. Hiki i ka lāʻau lapaʻau ke paʻakikī i kou kino ke pale aku i nā maʻi.

Pono nā poʻe me nā maʻi maʻi i ʻike ʻia i ka rilonacept a i ʻole kekahi o kāna mau mea e pale i kēia lāʻau. Inā loaʻa iā ʻoe nā hopena maʻi koʻikoʻi i nā lāʻau lapaʻau like, pono i kāu kauka e kaupaona pono i nā pilikia a me nā pōmaikaʻi.

Pono kekahi mau maʻi lapaʻau i ka noʻonoʻo kūikawā ma mua o ka hoʻomaka ʻana i ka rilonacept:

• Mōʻaukala o nā maʻi pinepine a koʻikoʻi paha
• Pūnaehana pale maʻi nāwaliwali mai nā kumu ʻē aʻe
• Tuberculosis hana a i ʻole mōʻaukala o ka tuberculosis
• Nā maʻi Hepatitis B a i ʻole C
• Nā lāʻau lapaʻau ola hou a i ʻole nā lāʻau lapaʻau ola i hoʻolālā ʻia
• Hāpai a hānai waiū paha

E hoʻāʻo paha kāu kauka iā ʻoe no ka tuberculosis a me ka hepatitis ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau, no ka mea, hiki i kēia mau maʻi ke lilo i mea koʻikoʻi ke kāohi ʻia kāu pūnaehana pale maʻi.

Inā hāpai ʻoe a i ʻole e hoʻolālā ana e hāpai, e kūkākūkā i kēia me kāu mea mālama ola. ʻAʻole i hoʻokumu piha ʻia ka palekana o ka rilonacept i ka wā hāpai, no laila pono kāu kauka e noʻonoʻo pono inā ʻoi aku ka maikaʻi ma mua o nā pilikia.

Nā inoa inoa o Rilonacept

Loaʻa ka Rilonacept ma lalo o ka inoa inoa ʻo Arcalyst ma ʻAmelika Hui Pū ʻIa. ʻO kēia ka formulation inoa inoa wale nō i loaʻa i kēia manawa, no ka mea, aia nō ka rilonacept ma lalo o ka pale patent a ʻaʻole i loaʻa nā mana generic.

Hana ʻia ʻo Arcalyst e Regeneron Pharmaceuticals a hele mai ma ke ʻano he pauka no ka injection e pono ai ka hui ʻana ma mua o ka hoʻohana ʻana. Hoʻolaha ʻia ka lāʻau lapaʻau ma o nā hale kūʻai lāʻau lapaʻau kūikawā ma muli o kāna mau koi mālama kūikawā a me ka pono no ka hoʻonaʻauao maʻi kūpono.

Ke kūkākūkā ʻana i kāu kauoha me nā mea mālama ola a i ʻole nā ​​kauka lāʻau, hiki iā ʻoe ke kuhikuhi i ka lāʻau lapaʻau ma kona inoa generic (rilonacept) a i ʻole ka inoa inoa (Arcalyst). E pili ana nā huaʻōlelo ʻelua i ka lāʻau lapaʻau like.

Nā koho ʻē aʻe o Rilonacept

Nui nā lāʻau lapaʻau ʻē aʻe e hiki ke mālama i nā maʻi periodic e pili ana i ka cryopyrin, ʻoiai e hilinaʻi ka koho i kāu kūlana kikoʻī, nā hōʻailona, ​​a me ka maikaʻi o kāu pane ʻana i ka lāʻau lapaʻau. E kōkua kāu kauka e hoʻoholo i ka koho e hana maikaʻi loa no kāu kūlana.

ʻO Canakinumab (Ilaris) kekahi mea pale interleukin-1 i manaʻo pinepine ʻia he koho ʻē aʻe i ka rilonacept. Hāʻawi ʻia ia ma ke ʻano he injection i kēlā me kēia ʻewalu pule ma kahi o kēlā me kēia pule, kahi mea i ʻoi aku ka maʻalahi o kekahi poʻe. Eia naʻe, hana ia ma o kahi ʻano hana ʻokoʻa iki a loaʻa paha nā ʻano hopena ʻaoʻao like ʻole.

ʻO Anakinra (Kineret) kahi mea pale interleukin-1 kahiko e koi ana i nā injections i kēlā me kēia lā. ʻOiai he mea pono ia no ka nui o nā poʻe me nā maʻi mumū, hiki i ka papa hana injection i kēlā me kēia lā ke ʻoi aku ka paʻakikī ma mua o ka lāʻau lapaʻau o rilonacept i kēlā me kēia pule.

No kekahi poʻe me nā hōʻailona maʻalahi a i ʻole ka poʻe hiki ʻole ke lawe i nā lāʻau lapaʻau biologic, hiki ke noʻonoʻo ʻia nā lāʻau lapaʻau kuʻuna:

• Colchicine no ka poʻe me ka fiva Mediterranean familial
• ʻO nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) no ka mālama ʻana i nā hōʻailona
• Corticosteroids no ka mālama ʻana i ka mumū i ka wā pōkole
• Nā lāʻau immunosuppressive ʻē aʻe i nā kūlana kikoʻī

E noʻonoʻo kāu kauka i nā mea e like me kāu hoʻololi genetic kikoʻī, ka paʻakikī o nā hōʻailona, ​​nā makemake o ke ola, a me ka uhi ʻinikua i ka wā e ʻōlelo ai i nā koho ʻē aʻe. Pono paha kekahi poʻe e hoʻāʻo i nā lāʻau lapaʻau like ʻole e ʻike i ka mea e hana maikaʻi ai no lākou.

ʻOi aku ka maikaʻi o Rilonacept ma mua o Canakinumab?

He mau lāʻau lapaʻau maikaʻi ʻo Rilonacept a me canakinumab no nā maʻi periodic e pili ana i ka cryopyrin, akā loaʻa iā lākou nā pono like ʻole e pili ana i kāu mau pono a me nā makemake. ʻAʻole ʻoi aku ka maikaʻi o kekahi lāʻau lapaʻau ma mua o kekahi.

Pono ʻo Rilonacept i nā injections i kēlā me kēia pule, ʻo ia hoʻi ka nui o ka lāʻau lapaʻau akā ʻoi aku ka paʻa o nā pae lāʻau lapaʻau i kāu ʻōnaehana. Makemake kekahi poʻe i kēia no ka mea manaʻo lākou e mālama hou i kā lākou lapaʻau a hiki ke hoʻololi i ka manawa inā pono no ka huakaʻi a i ʻole nā ​​hana ʻē aʻe.

Hāʻawi ʻia ʻo Canakinumab i kēlā me kēia ʻewalu pule, he mea maʻalahi i ka nui o nā kānaka. Eia naʻe, ʻike kekahi poʻe i ka hōʻailona e puka mai ana i ka hopena o ka manawa hoʻohana, e koi ana i nā injections pinepine a i ʻole nā lāʻau lapaʻau hou.

ʻO ke koho ma waena o kēia mau lāʻau lapaʻau e hilinaʻi pinepine ana i nā mea hana:

• ʻO kou makemake no ka pinepine o ka injection
• Pehea ka maikaʻi o kēlā me kēia lāʻau lapaʻau e kāohi ai i kāu mau hōʻailona kikoʻī
• Ka uhi ʻana o ka ʻinikua a me nā manaʻo kumukūʻai
• Nā ʻaoʻao hopena a me kou ʻae ʻana
• ʻO ka ʻike o kāu kauka me kēlā me kēia lāʻau lapaʻau

Hiki i kekahi poʻe ke pane maikaʻi i kekahi lāʻau lapaʻau ma mua o kekahi, a ʻaʻole hiki ke wānana i ka mea e hana maikaʻi loa ai iā ʻoe. Hiki i kāu kauka ke ʻōlelo e hoʻomaka me kekahi a hoʻololi inā pono e pili ana i kāu pane.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Rilonacept

He Palekana ʻo Rilonacept no ka poʻe me ka maʻi diabetes?

Hiki ke hoʻohana palekana ʻia ʻo Rilonacept i ka poʻe me ka maʻi diabetes, akā pono kāu hui mālama ola e nānā pono iā ʻoe. ʻAʻole pili pololei ka lāʻau lapaʻau i nā pae kōpaʻa koko, akā hiki i nā maʻi (ʻoi aku ka maʻalahi o ʻoe i ka wā e lawe ana iā rilonacept) ke paʻakikī i ka mālama ʻana i ka maʻi diabetes.

Inā loaʻa iā ʻoe ka maʻi diabetes, e hōʻoia e mālama i ka mana maikaʻi o ke kōpaʻa koko a nānā i nā hōʻailona o ka maʻi me ka mālama nui. Hiki i kāu kauka ke ʻōlelo i nā loiloi pinepine a me ka nānā ʻana i ke kōpaʻa koko, ʻoiai ke hoʻomaka ʻana i ka lāʻau lapaʻau.

He aha kaʻu e hana ai inā hoʻohana hewa au i ka nui o Rilonacept?

Inā ʻoe e hoʻokomo hewa i ka nui o ka rilonacept ma mua o ka mea i kauoha ʻia, e hoʻokaʻaʻike koke i kāu mea mālama ola a i ʻole ke kikowaena mana ʻawaʻawa. ʻOiai he kakaikahi nā overdoses me rilonacept, hiki i ka lawe ʻana i ka nui ke hoʻonui i kou pilikia o nā maʻi koʻikoʻi a i ʻole nā hopena ʻē aʻe.

Mai ho'āʻo e "hoʻoponopono" i ka overdose ma ka haʻalele ʻana i nā lāʻau i ka wā e hiki mai ana a i ʻole ka lawe ʻana i ka lāʻau liʻiliʻi. E aʻo aku kāu kauka iā ʻoe i ke ala maikaʻi loa o ka hana, e komo paha i ka nānā ʻana i nā hopena ʻē aʻe a i ʻole ka hoʻoponopono ʻana i kāu lāʻau i hoʻonohonoho ʻia e hiki mai ana.

He aha kaʻu e hana ai inā ua hala wau i kahi lāʻau o Rilonacept?

Inā ua hala ʻoe i kāu lāʻau rilonacept i kēlā me kēia pule, e lawe koke iā ia ke hoʻomanaʻo ʻoe, a laila e hoʻomau me kāu papa hana pule maʻamau. Mai pāpālua i nā lāʻau e uku no ka injection i hala.

Inā ua hala ʻoe ma mua o kekahi mau lā me kāu lāʻau, e hoʻokaʻaʻike i kāu mea mālama ola no ke alakaʻi. Hiki iā lākou ke ʻōlelo aku i ka hoʻoponopono ʻana i kāu papa hana a i ʻole ka nānā ʻana iā ʻoe no ka hoʻi ʻana mai o nā hōʻailona.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Rilonacept?

Pono ʻoe e hooki i ka lawe ʻana iā rilonacept ma lalo o ka mālama ʻana a kāu kauka. No ka mea, he mau maʻi genetic nā maʻi periodic e pili ana i ka cryopyrin, pono ka hapa nui o nā kānaka i ka lāʻau lapaʻau e mālama i nā hōʻailona.

Hiki i kāu kauka ke noʻonoʻo e hooki a hoʻemi paha i ka rilonacept inā ʻoe e ʻike i nā hopena ʻaoʻao koʻikoʻi, inā e loli nui ana kou kūlana, a i ʻole inā loaʻa nā koho lapaʻau hou. E hana pū lākou me ʻoe e hoʻomohala i kahi hoʻolālā e mālama ai i ka mana o nā hōʻailona me ka hōʻemi ʻana i nā pilikia.

Hiki iaʻu ke loaʻa nā lāʻau lapaʻau i ka wā e lawe ana iā Rilonacept?

Pono ʻoe e pale i nā lāʻau lapaʻau ola i ka wā e lawe ana iā rilonacept, no ka mea, ʻaʻole hiki i kāu ʻōnaehana pale i hoʻopaʻa ʻia ke mālama pono iā lākou. Eia naʻe, palekana a paipai ʻia nā lāʻau lapaʻau i pepehi ʻia a i ʻole i hoʻopau ʻia.

E kamaʻilio me kāu kauka ma mua o ka loaʻa ʻana o nā lāʻau lapaʻau, me nā mea maʻamau e like me ka pana flu. Hiki iā lākou ke ʻōlelo aku i ka manawa o nā lāʻau lapaʻau a puni kāu mau lāʻau rilonacept a i ʻole ka hōʻoia ʻana ua hiki ʻoe i ka lā ma nā lāʻau lapaʻau koʻikoʻi ma mua o ka hoʻomaka ʻana i ka lāʻau.