He aha ʻo Riociguat: Nā hoʻohana, ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau ʻo Riociguat e kōkua ana i ka mālama ʻana i nā maʻi māmā ʻelua koʻikoʻi ma ka hoʻomaikaʻi ʻana i ke kahe koko ma nā aʻa pulmonary. Hana ia ma ka hoʻomaha ʻana i nā kīʻaha koko i loko o kou mau māmā, e maʻalahi ai i kou puʻuwai ke pauma i ke koko a kōkua iā ʻoe e hanu me ka ʻoluʻolu.

No kēia lāʻau lapaʻau i kahi papa lāʻau hou i kapa ʻia he soluble guanylate cyclase stimulators. E noʻonoʻo iā ia he mea kōkua mālie e paipai ana i nā kīʻaha koko o kou māmā e wehe ākea, e hōʻemi ana i ke kaumaha ma kou puʻuwai a hoʻomaikaʻi i kou ola maikaʻi.

No ke aha e hoʻohana ʻia ai ʻo Riociguat?

Hoʻomaʻamaʻa ʻo Riociguat i ʻelua ʻano maʻi pulmonary hypertension, ʻo ia ke koko kiʻekiʻe i loko o nā aʻa o kou mau māmā. Hiki i kāu kauka ke kau i kēia lāʻau lapaʻau inā loaʻa iā ʻoe ka chronic thromboembolic pulmonary hypertension (CTEPH) a i ʻole pulmonary arterial hypertension (PAH).

Hiki mai ʻo CTEPH ke ʻole e hoʻoheheʻe pono nā koko koko i loko o kou mau aʻa māmā, e hana ana i nā poloka e hana nui ai kou puʻuwai. Hiki mai ʻo PAH ke lilo nā aʻa liʻiliʻi i loko o kou mau māmā i ka liʻiliʻi a me ka paʻakikī, e hoʻonui ana i ke kaomi i loko o kāu pulmonary circulation.

Hiki i nā maʻi ʻelua ke hoʻopōkole iā ʻoe i ka hanu, luhi, a kaupalena i kou hiki ke hana i nā hana o kēlā me kēia lā. Kōkua ʻo Riociguat ma ka wehe ʻana i kēia mau kīʻaha koko i hoʻopaʻa ʻia, hiki ke hoʻomaikaʻi i kou hoʻomanawanui ʻana i ka hoʻoikaika kino a kōkua iā ʻoe e manaʻo hou e like me ʻoe iho.

Pehea e hana ai ʻo Riociguat?

Hana ʻo Riociguat ma ka hoʻopaʻa ʻana i kahi ʻōnaehana enzyme kikoʻī i loko o kou mau kīʻaha koko i kapa ʻia ʻo soluble guanylate cyclase. Hoʻoulu kēia lāʻau lapaʻau i kēia ʻōnaehana e hana i ka nui o kahi mea maoli i kapa ʻia ʻo cyclic GMP, e haʻi ana i kou mau kīʻaha koko e hoʻomaha a ākea.

He lāʻau lapaʻau ikaika kēia i manaʻo ʻia e hana ʻokoʻa mai nā lāʻau lapaʻau hypertension pulmonary ʻē aʻe. ʻOiai e hana ana kekahi mau lāʻau lapaʻau ke loaʻa ka nitric oxide, hiki i ka riociguat ke hana ʻoiai nā haʻahaʻa o ka nitric oxide, e hana ana i mea maikaʻi no nā maʻi hou aku.

Hoʻomaka maʻamau ka lāʻau lapaʻau i loko o kekahi mau pule, ʻoiai ʻaʻole paha ʻoe e ʻike i nā pōmaikaʻi piha no kekahi mau mahina. E nānā pono kāu kauka i kāu holomua a hoʻoponopono i kāu mahele e like me ka mea e pono ai e ʻike i ka mea e hana maikaʻi ai iā ʻoe.

Pehea e lawe ai au i ka Riociguat?

E lawe i ka riociguat e like me ke kauoha a kāu kauka, ʻekolu manawa i ka lā me ka ʻole o ka meaʻai. Hiki iā ʻoe ke lawe me ka wai, a maikaʻi maʻamau ke lawe me nā meaʻai inā kōkua ia iā ʻoe e hoʻomanaʻo a i ʻole he maʻalahi ma kou ʻōpū.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi mahele haʻahaʻa a hoʻonui mālie i loko o kekahi mau pule. Kōkua kēia hana mālama i kou kino e hoʻoponopono i ka lāʻau lapaʻau a hōʻemi i ka manawa o nā hopena ʻaoʻao e like me ka dizziness a i ʻole ke koko haʻahaʻa.

E hoʻāʻo e lawe i kāu mau mahele i nā manawa like i kēlā me kēia lā, e hoʻokaʻawale iā lākou ma kahi o 6 a 8 mau hola. Hiki i ka hoʻonohonoho ʻana i nā mea hoʻomanaʻo kelepona ke kōkua iā ʻoe e mālama i kahi papa hana mau, he mea nui ia no ka mālama ʻana i nā pae paʻa o ka lāʻau lapaʻau i kāu ʻōnaehana.

Inā pono ʻoe e ʻoki i nā papa no ka ʻai maʻalahi, e nānā mua me kāu kauka lāʻau. Hiki ke ʻoki ʻia kekahi mau formulations a hui pū ʻia me ka wai a i ʻole ka ʻāpala, akā ʻoi aku ka maikaʻi o ka hōʻoia ʻana he palekana kēia me kāu hui mālama ola.

Pehea ka lōʻihi e lawe ai au i ka Riociguat?

ʻO ka Riociguat kahi lāʻau lapaʻau lōʻihi e pono ai ʻoe e hoʻomau i ka wā e kōkua ana i kou maʻi a ʻaʻole e hana i nā hopena ʻaoʻao pilikia. Pono ka hapa nui o ka poʻe me ka pulmonary hypertension i ka lāʻau lapaʻau e mālama pono i ko lākou maʻi.

E loiloi mau kāu kauka i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau ma o nā hālāwai ukali, nā hoʻokolohua hoʻoikaika kino, a i kekahi manawa nā haʻawina kiʻi. Kōkua kēia mau loiloi e hoʻoholo inā ʻo riociguat ka koho kūpono iā ʻoe a i ʻole pono e hoʻoponopono.

Mai hooki koke i ka lawe ʻana iā riociguat me ka ʻole e kamaʻilio mua me kāu kauka. Hiki ke ʻino koke kou maʻi inā e hooki koke ʻoe i ka lāʻau lapaʻau, no laila pono e hana mālie ʻia nā loli i kāu hoʻolālā lapaʻau ma lalo o ka mālama ʻana o ke kauka.

He aha nā hopena ʻaoʻao o Riociguat?

E like me nā lāʻau lapaʻau a pau, hiki i ka riociguat ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole ʻike nā kānaka a pau iā lākou. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a maʻamau e hoʻomaikaʻi i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau.

Eia nā hopena ʻaoʻao āu e ʻike ai, e hoʻomaka ana me nā mea maʻamau:

• ʻEha poʻo, e emi pinepine ana i ka manawa
• ʻĀwili a i ʻole ka māmā, ʻoiai i ke kū ʻana
• Nausea a i ʻole ka ʻōpū
• Pāpaʻa a i ʻole nā ʻōpala
• Pehu i kou mau wāwae, nā kuʻekuʻe wāwae, a i ʻole nā wāwae
• Luhi a i ʻole ka luhi ma mua o ka maʻamau

ʻO kēia mau hopena ʻaoʻao maʻamau e lilo pinepine i mea liʻiliʻi i ka wā e maʻa ai kou kino i ka lāʻau lapaʻau. Inā mau lākou a hopohopo paha iā ʻoe, mai kānalua e kūkākūkā me kāu mea mālama ola.

ʻO kekahi mau hopena ʻaoʻao liʻiliʻi akā ʻoi aku ka koʻikoʻi e koi i ka lāʻau lapaʻau koke. Aia kēia mau mea i ka:

• Hāʻule nui i ke koko e hōʻeha ai i ka maʻi
• ʻEha umauma a i ʻole ka puʻuwai ʻole
• Ke kahe nui ʻana a i ʻole ka ʻeha maʻamau
• Nā hōʻailona o nā pilikia o ka māmā e like me ka ʻū hou a i ʻole ka ʻino me ke koko
• Nā hopena maʻi koʻikoʻi me ka ʻulaʻula, ka pehu, a i ʻole ka pilikia o ka hanu

ʻOiai ʻaʻole maʻamau kēia mau hopena ʻaoʻao koʻikoʻi, he mea nui e ʻike iā lākou a e ʻimi koke i ke kōkua olakino inā loaʻa lākou. Ua kauoha kāu kauka iā riociguat no ka mea manaʻo lākou e ʻoi aku ka maikaʻi ma mua o kēia mau pilikia no kou kūlana.

ʻO wai ka mea pono ʻole e lawe iā Riociguat?

ʻAʻole kūpono ʻo Riociguat no nā mea a pau, a aia kekahi mau kūlana koʻikoʻi e pono ai e pale ʻia kēia lāʻau lapaʻau. E nānā pono kāu kauka i kāu moʻolelo olakino a me nā lāʻau lapaʻau i kēia manawa ma mua o ke kau ʻana iā riociguat.

ʻAʻole pono ʻoe e lawe iā riociguat inā e hoʻohana nei ʻoe i kekahi mau lāʻau lapaʻau e hiki ke launa pū me ia:

• Nitrates e like me nitroglycerin no ka ʻeha o ka umauma
• Phosphodiesterase-5 inhibitors e like me sildenafil a i ʻole tadalafil
• Nā lāʻau lapaʻau hypertension pulmonary ʻē aʻe i ka papa like
• Nā lāʻau antifungal a i ʻole protease inhibitors

He nui nā maʻi olakino e hoʻolilo i ka riociguat i kūpono ʻole a i ʻole e koi i nā hana kūikawā:

• Maʻi ate koʻikoʻi a i ʻole nā pilikia ate nui
• Ke koko haʻahaʻa a i ʻole ka mōʻaukala o ka fainting spells
• Maʻi kīkī koʻikoʻi e koi ana i ka dialysis
• ʻO ka hahau ʻana a i ʻole ka puʻuwai i ka wā i hala
• Hāpai a i ʻole nā hoʻolālā e hāpai

Eia kekahi, hiki i ka riociguat ke hoʻoulu i nā kīnā hānau koʻikoʻi, no laila pono nā wahine o ka makahiki hānau i ka contraception hilinaʻi i ka wā e lawe ana i kēia lāʻau lapaʻau. E kūkākūkā kāu kauka i nā hoʻolālā pale hāpai me ʻoe inā pili kēia i kou kūlana.

Nā inoa inoa o Riociguat

Loaʻa ʻo Riociguat ma lalo o ka inoa inoa Adempas ma ʻAmelika Hui Pū ʻIa a me nā ʻāina ʻē aʻe. ʻO kēia ka inoa inoa mua āu e ʻike ai ke kauoha kāu kauka i kēia lāʻau lapaʻau.

E hāʻawi maʻamau kāu lāʻau lapaʻau iā Adempas ke ʻole kāu kauka e kākau kikoʻī no kahi mana generic, ʻoiai ʻaʻole paha i loaʻa ka riociguat generic ma nā wahi āpau. He like ka mea hana ikaika me ka inoa inoa.

Inā he mau nīnau kāu e pili ana i ka uhi ʻinikua e pili ana i ka inoa inoa a me nā koho generic, hiki i kāu lāʻau lapaʻau ke kōkua iā ʻoe e hoʻomaopopo i kāu mau pōmaikaʻi kikoʻī a me nā ʻokoʻa kumukūʻai e pili ana.

Nā Koho ʻē aʻe o Riociguat

Nui nā lāʻau lapaʻau ʻē aʻe e hiki ke mālama i ka maʻi hypertension pulmonary, ʻoiai e hana ʻokoʻa kēlā me kēia a ʻoi aku paha ke kūpono no nā maʻi like ʻole. E koho kāu kauka i ke koho maikaʻi loa e pili ana i kāu ʻano kikoʻī o ka hypertension pulmonary a me ke olakino holoʻokoʻa.

ʻO nā koho lāʻau lapaʻau ʻē aʻe no ka hypertension pulmonary:

• Nā mea pale phosphodiesterase-5 e like me sildenafil a i ʻole tadalafil
• Nā mea kūʻē i ka mea hoʻokipa Endothelin e like me bosentan a i ʻole ambrisentan
• Nā analog prostacyclin e like me epoprostenol a i ʻole treprostinil
• Nā mea pale kahawai calcium no kekahi mau maʻi

I kekahi manawa e kauoha nā kauka i nā hui pū ʻana o kēia mau lāʻau lapaʻau e kuhikuhi i nā ala like ʻole i ka hypertension pulmonary. Aia ke koho i nā mea e like me kāu hōʻailona kikoʻī, pehea ke koʻikoʻi o kou maʻi, a pehea kou ʻae ʻana i nā lāʻau lapaʻau like ʻole.

Hiki nō hoʻi i kāu kauka ke noʻonoʻo i nā lāʻau lapaʻau ʻole e like me ka oxygen therapy, ka hoʻoponopono hou ʻana i ka pulmonary, a i ʻole nā hihia koʻikoʻi, ka transplantation māmā. ʻO ka pahuhopu ka loaʻa ʻana o ke ala e hāʻawi iā ʻoe i ka maikaʻi o ke ola me ka liʻiliʻi o nā hopena ʻaoʻao.

Ua ʻoi aku ka maikaʻi o Riociguat ma mua o Sildenafil?

Hana ʻo Riociguat a me sildenafil ma nā ʻano hana like ʻole, no laila ʻaʻole pono kekahi i ʻoi aku ka maikaʻi ma mua o kekahi no nā maʻi āpau. Aia ke koho i kāu ʻano kikoʻī o ka hypertension pulmonary a me nā kūlana pilikino.

He pōmaikaʻi kū hoʻokahi ko Riociguat no ka mea hiki ke hana ʻoiai nā pae nitric oxide haʻahaʻa, kahi e pono ai no nā maʻi CTEPH. Ma ka ʻaoʻao ʻē aʻe, ua hoʻohana ʻia ʻo Sildenafil no ka manawa lōʻihi a loaʻa nā ʻikepili noiʻi nui e kākoʻo ana i kāna hoʻohana ʻana i ka PAH.

E noʻonoʻo kāu kauka i nā mea e like me kāu hōʻailona pololei, nā maʻi olakino ʻē aʻe, nā lāʻau lapaʻau o kēia manawa, a me ke ʻano o kāu pane ʻana i nā lāʻau lapaʻau ma mua. ʻOi aku ka maikaʻi o kekahi poʻe maʻi me kekahi lāʻau lapaʻau ma mua o kekahi, a ʻo nā mea ʻē aʻe e pōmaikaʻi paha mai ka lāʻau hui pū.

ʻO ka mea nui ka loaʻa ʻana o ka lāʻau lapaʻau e hana maikaʻi loa no kou kūlana pilikino. Hiki i kāu kauka ke kōkua iā ʻoe e hoʻomaopopo i ke kumu e ʻōlelo nei lākou iā riociguat a me ka mea e manaʻo ai i ka hoʻohālikelike ʻana i nā koho ʻē aʻe.

Nā Nīnau i Nīnau pinepine ʻia e pili ana iā Riociguat

He palekana anei ʻo Riociguat no ka poʻe me ka maʻi puʻuwai?

Hiki ke hoʻohana ʻia ʻo Riociguat i ka poʻe me kekahi mau ʻano maʻi puʻuwai, akā pono ia i ka nānā pono ʻana a me ka noʻonoʻo ʻana i kou olakino cardiac holoʻokoʻa. E loiloi kāu kauka i kāu hana puʻuwai a me ke koko ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau.

Inā loaʻa iā ʻoe ka maʻi puʻuwai, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi haʻahaʻa haʻahaʻa a nānā pono iā ʻoe no nā hopena ʻaoʻao e like me ke koko haʻahaʻa a i ʻole nā ​​hoʻololi i ka puʻuwai. E hana pū lākou me kāu cardiologist e hōʻoia i ka hana maikaʻi ʻana o kāu mau lāʻau lapaʻau a pau.

ʻO ke kī ke kamaʻilio hāmama me kāu hui mālama ola e pili ana i kāu mau hōʻailona e pili ana i ka puʻuwai a me nā lāʻau lapaʻau. Kōkua kēia iā lākou e hana i nā hoʻoholo lapaʻau palekana a maikaʻi loa no kou kūlana.

He aha kaʻu e hana ai inā ua lawe au i ka nui o Riociguat?

Inā lawe ʻoe i ka nui o riociguat, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena mana ʻona, ʻoiai inā maikaʻi ʻoe. ʻO ka lawe ʻana i ka nui hiki ke hoʻohaʻahaʻa i ke koko, ka ʻūlū nui, a i ʻole ka hāʻule.

I ka wā e kali ana i ke alakaʻi olakino, e noho a i ʻole e moe i lalo e pale i ka hāʻule ʻana inā ʻoe e manaʻo i ka wili. Mai hoʻāʻo e hoʻokele a i ʻole e hana i nā mīkini, a e loaʻa i kekahi e noho pū me ʻoe inā hiki a hiki i kou hiki ke kamaʻilio me kahi mea mālama ola.

E mālama i kāu hue lāʻau lapaʻau i ka wā e kāhea ai ʻoe i ke kōkua, no ka mea, makemake nā poʻe loea lapaʻau e ʻike pololei i ka nui āu i lawe ai a me ka manawa. He mea nui ka hana wikiwiki, no laila, mai kali e ʻike inā e ulu ana nā hōʻailona.

He aha kaʻu e hana ai inā ua hala wau i kahi mahele o Riociguat?

Inā ua hala ʻoe i kahi mahele o riociguat, e lawe koke iā ia ke hoʻomanaʻo ʻoe, ke ʻole kokoke ka manawa no kāu mahele i hoʻonohonoho ʻia. I kēlā hihia, e lele i ka mahele i hala a e hoʻomau me kāu papa hana maʻamau.

Mai lawe i ʻelua mahele i ka manawa like e hoʻopiha ai i kahi mahele i hala, no ka mea, hiki i kēia ke hoʻohaʻahaʻa loa i kou koko. ʻOi aku ka maikaʻi o ka hala ʻana i hoʻokahi mahele ma mua o ka pāpālua ʻana a me ka pilikia o nā hopena ʻaoʻao koʻikoʻi.

Inā poina pinepine ʻoe i nā mahele, e noʻonoʻo e hoʻonohonoho i nā ʻōhua kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e noho ma ke ala. He mea nui ka hoʻopaʻa ʻana i ka mahele no ka mālama pono ʻana i kou hypertension pulmonary.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Riociguat?

Pono ʻoe e hooki i ka lawe ʻana iā riociguat ma lalo o ka mālama ʻana a kāu kauka, no ka mea, ʻo ka hooki ʻana i ka hikiwawe hiki ke hoʻonui wikiwiki i kāu mau hōʻailona hypertension pulmonary. E kōkua kāu kauka iā ʻoe e hoʻoholo inā a i ka manawa e kūpono ai ke hooki i ka lāʻau.

ʻO nā kumu e noʻonoʻo ai e hooki paha me nā hopena ʻaoʻao koʻikoʻi ʻaʻole e hoʻomaikaʻi, ka nele o ka pōmaikaʻi ma hope o kahi manawa hoʻokolokolo kūpono, a i ʻole inā pono ʻoe e hoʻololi i kahi lāʻau ʻē aʻe. E kaupaona kāu kauka i kēia mau mea me ʻoe.

Inā pono ʻoe e hooki i ka riociguat, e hoʻemi paha kāu kauka i ka mahele me ka mālie ma mua o ka hooki ʻana i ka hikiwawe. Kōkua kēia i ka pale ʻana i ka hoʻonui koke ʻana o kou maʻi a hāʻawi i kou kino i ka manawa e hoʻoponopono ai.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana iā Riociguat?

He mea maikaʻi e kaupalena i ka inu ʻana i ka waiʻona i ka wā e lawe ana i ka riociguat, no ka mea, hiki i ka waiʻona a me ka riociguat ke hoʻohaʻahaʻa i kou koko. Ke hui pū ʻia, hiki iā lākou ke hoʻohaʻahaʻa nui i ke koko, e alakaʻi ana i ka wili, ka hāʻule ʻana, a i ʻole ka hāʻule.

Inā koho ʻoe e inu i kekahi manawa, e hana me ka maʻalahi a e nānā i kou manaʻo. E hoʻomaka me nā mea liʻiliʻi e ʻike pehea e pane ai kou kino, a e ʻai mau i ka meaʻai i ka wā e inu ai i ka waiʻona.

E kamaʻilio me kāu kauka e pili ana i ka nui o ka inu ʻana i ka waiʻona, inā he mea palekana iā ʻoe i ka wā e lawe ana i ka riociguat. Hiki iā lākou ke hāʻawi iā ʻoe i ka ʻōlelo aʻo pilikino e pili ana i kou olakino holoʻokoʻa a me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.