He aha ʻo Saxagliptin a me Metformin: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Saxagliptin a me metformin he lāʻau hui e kōkua ana i ka mālama ʻana i ka maʻi diabetes type 2 ma ka hana ʻana ma nā ʻano like ʻole e mālama i nā pae kōpaʻa koko. Hoʻohui kēia lāʻau lapaʻau i ʻelua mau lāʻau lapaʻau diabetes i hōʻoia ʻia i loko o hoʻokahi pila maʻalahi, e maʻalahi ai iā ʻoe ke pili i kāu hoʻolālā lapaʻau.

Inā ua kau ʻia kēia lāʻau lapaʻau iā ʻoe, ke noʻonoʻo nei paha ʻoe pehea e hana ai a me ka mea e manaʻo ai. E hele kākou i nā mea a pau e pono ai ʻoe e ʻike e pili ana i kēia lāʻau lapaʻau diabetes ma ke ʻano e maʻalahi a maopopo.

He aha ʻo Saxagliptin a me Metformin?

ʻO Saxagliptin a me metformin he lāʻau lapaʻau i kau ʻia i loaʻa i ʻelua mau mea hana e hana pū ana e kōkua i ka mālama ʻana i ke kōpaʻa koko i ka poʻe me ka maʻi diabetes type 2. E noʻonoʻo iā ia he ala hui kahi e hoʻoponopono ai kēlā me kēia lāʻau lapaʻau i ke kōpaʻa koko mai kahi kihi ʻokoʻa.

No ka hui o nā lāʻau lapaʻau i kapa ʻia ʻo DPP-4 inhibitors ʻo Saxagliptin, e kōkua ana i kou kino e hana i ka insulin hou aʻe ke kiʻekiʻe kou kōpaʻa koko. No ka hui i kapa ʻia ʻo biguanides ʻo Metformin, a kōkua ia e hōʻemi i ka nui o ke kō e hana ai kou ate aʻo ke kōkua nei i kou kino e hoʻohana i ka insulin ʻoi aku ka maikaʻi.

Loaʻa kēia lāʻau lapaʻau hui ma ke ʻano he papa e lawe ʻoe ma ka waha, maʻamau ʻelua manawa i ka lā me nā meaʻai. Kau kāu kauka i kēia ke hāʻawi ʻole nā lāʻau lapaʻau hoʻokahi i ka mana kōpaʻa koko lawa ma kā lākou iho.

No ke aha e hoʻohana ʻia ai ʻo Saxagliptin a me Metformin?

Hoʻolālā ʻia kēia lāʻau lapaʻau e mālama i ka maʻi diabetes type 2 i nā pākeke ke ʻaʻole lawa ka ʻai a me ka hoʻoikaika kino wale nō e mālama i nā pae kōpaʻa koko. He mea kōkua nui ia no ka poʻe e pono ai ma mua o hoʻokahi ʻano lāʻau lapaʻau diabetes e hiki ai i kā lākou mau pahuhopu kōpaʻa koko.

Hiki i kāu kauka ke kuhikuhi i kēia hui inā ua lawe ʻoe i ka metformin wale nō akā he kiʻekiʻe nō nā helu kōpaʻa koko. Hoʻohana ʻia nō hoʻi ke pono ʻoe i nā lāʻau ʻelua akā makemake ʻoe i ka maʻalahi o ka lawe ʻana i hoʻokahi pila ma kahi o ʻelua mau mea ʻokoʻa.

Hana maikaʻi ka lāʻau lapaʻau ma ke ʻano he ʻāpana o kahi hoʻolālā mālama maʻi diabetes piha e pili ana i ka ʻai olakino, ka hana kino maʻamau, a me ka mālama ʻana i ke kaumaha ke kūpono. ʻAʻole i manaʻo ʻia e pani i kēia mau ala ola nui akā e hana pū me lākou.

Pehea e Hana ai ʻo Saxagliptin a me Metformin?

Hana kēia hui lāʻau lapaʻau ma o nā ʻano hana ʻelua like ʻole e kōkua i ka mālama ʻana i kou kōpaʻa koko i kahi pae olakino. Kōkua ka ʻāpana saxagliptin i kou pancreas e hoʻokuʻu i ka insulin hou aʻe ke piʻi kou kōpaʻa koko ma hope o ka ʻai ʻana, ʻoiai e hōʻemi ana i ka nui o ka glucose e hana ai kou ate.

Hana nui ka mea metformin ma ka hoʻēmi ʻana i ka nui o ke kō e hana ai kou ate a hoʻokuʻu i loko o kou kahe koko. Kōkua pū ia i kāu mau ʻiʻo a me nā cell momona e ʻoi aku ka naʻau i ka insulin, ʻo ia hoʻi hiki iā lākou ke hoʻohana i ka glucose me ka ʻoi aku ka maikaʻi.

ʻO ka hui pū ʻana, hāʻawi kēia mau lāʻau lapaʻau ʻelua i ka mea a nā kauka e kapa ai he

E hoʻāʻo e lawe i kāu mau lāʻau i nā manawa like i kēlā me kēia lā e mālama i nā pae paʻa o ka lāʻau i loko o kou kino. He nui ka poʻe i ʻike he mea kōkua ke hoʻopili ʻana i ka lawe ʻana i kā lākou lāʻau i nā meaʻai maʻamau, e like me ka ʻaina kakahiaka a me ka ʻaina ahiahi, e hoʻokumu i kahi hana maʻamau.

Ma mua o ka hoʻomaka ʻana i kēia lāʻau, e ʻai i ka meaʻai māmā a i ʻole ka ʻai e kōkua i ka pale ʻana i ka ʻoluʻolu o ka ʻōpū. ʻO nā meaʻai e maʻalahi ai i kou ʻōpū, e like me ka toast, crackers, a i ʻole yogurt, hana maikaʻi inā hopohopo ʻoe e pili ana i ka nausea.

Pehea ka lōʻihi e lawe ai au i ka Saxagliptin a me Metformin?

He maʻi lōʻihi ka maʻi diabetes type 2, no laila pono ka hapa nui o ka poʻe e lawe i kēia lāʻau no nā makahiki he nui a i ʻole no ka manawa pau ʻole e mālama i ka mana maikaʻi o ke kō koko. E nānā mau kāu kauka i kāu pae kō koko a me ke olakino holoʻokoʻa e hoʻoholo ai inā he koho kūpono kēia lāʻau lapaʻau iā ʻoe.

I nā mahina mua o kāu lāʻau lapaʻau, e loaʻa paha iā ʻoe nā nānā pinepine a me nā hoʻokolohua koko e hōʻoia i ka hana maikaʻi ʻana a ʻaʻole e hana i nā pilikia. Ma hope o kēlā, nānā ʻia nā lāʻau lapaʻau diabetes a ka hapa nui o ka poʻe i kēlā me kēia ʻekolu a ʻeono mahina.

Hiki i kāu kauka ke hoʻoponopono i kāu mahele a i ʻole e hoʻololi iā ʻoe i nā lāʻau lapaʻau like ʻole i ka wā e loli ai nā pono o kou kino. He mea maʻamau kēia a ʻaʻole ia he manaʻo ʻaʻole e hana ana ka lāʻau - ʻo ia wale nō ka manaʻo e hoʻoponopono ʻia kāu hoʻolālā lapaʻau no kou kūlana olakino i kēia manawa.

He aha nā hopena ʻaoʻao o Saxagliptin a me Metformin?

E like me nā lāʻau lapaʻau a pau, hiki i ka saxagliptin a me ka metformin ke hana i nā hopena ʻaoʻao, ʻoiai he nui ka poʻe e ʻae maikaʻi iā ia. ʻO nā hopena ʻaoʻao maʻamau ka maʻamau a hoʻomaikaʻi pinepine i ka wā e hoʻoponopono ai kou kino i ka lāʻau i nā pule mua.

Eia nā hopena ʻaoʻao e ʻike nui ai ʻoe, me ka noʻonoʻo ʻana he mea maʻamau nā pilikia e pili ana i ka ʻōpū:

• ʻO ka luaʻau a i ʻole ka ʻoluʻolu o ka ʻōpū
• Ka maʻi palahī a i ʻole nā ʻōpū palupalu
• ʻEha poʻo
• Nā maʻi o ka ʻōnaehana hanu luna e like me ke anu
• He ʻono metala i loko o kou waha
• Ua emi ka ʻai

He mea maʻamau kēia mau hopena ʻaoʻao a he mea hiki ke mālama ʻia. ʻO ka lawe ʻana i ka lāʻau me ka meaʻai a me ka hoʻomaka ʻana me nā mea liʻiliʻi hiki ke kōkua i ka hōʻemi ʻana i nā pilikia o ka ʻōpū.

I kēia manawa, e kamaʻilio kākou e pili ana i kekahi mau hopena ʻaoʻao ʻaʻole maʻamau akā ʻoi aku ka koʻikoʻi e pono ai ka lāʻau lapaʻau koke:

• ʻEha ʻōpū nui ʻaʻole e pau
• Ka luaʻau mau a me ka luaʻi
• ʻEha ʻiʻo ʻokoʻa a i ʻole nāwaliwali
• He pilikia i ka hanu ʻana a i ʻole ka hanu wikiwiki
• Nā hopena ʻili nui a i ʻole ka ʻōpala
• Nā hōʻailona o nā pilikia o ka puʻupaʻa e like me nā loli i ka mimi

ʻOiai he mea maʻamau ʻole kēia mau hopena ʻaoʻao koʻikoʻi, he mea nui e ʻike iā lākou i ka wā mua. Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, ​​e kelepona koke i kāu kauka a i ʻole e ʻimi i ka lāʻau lapaʻau pilikia.

Aia kekahi maʻi maʻamau loa akā koʻikoʻi i kapa ʻia ʻo ka lactic acidosis e hiki ke hana me ka metformin. Hana ʻia kēia i ka wā e kūkulu ai ka waikawa lactic i loko o kou koko i ka wikiwiki ma mua o ka hiki i kou kino ke wehe. ʻO nā hōʻailona hōʻailona e pili ana i ka ʻeha ʻiʻo ʻokoʻa, ka pilikia o ka hanu ʻana, ka ʻeha o ka ʻōpū, ka ʻūlū, a me ka manaʻo nāwaliwali a luhi paha.

ʻO wai ka mea pono ʻole e lawe iā Saxagliptin a me Metformin?

ʻAʻole kūpono kēia lāʻau lapaʻau no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ke kau ʻana. Pono ka poʻe me kekahi mau maʻi olakino a i ʻole nā ​​kūlana e pale loa i kēia lāʻau hui.

ʻAʻole pono ʻoe e lawe i kēia lāʻau lapaʻau inā loaʻa iā ʻoe ka maʻi diabetes type 1 a i ʻole ka diabetic ketoacidosis, no ka mea, ua hoʻolālā ʻia no ka mālama ʻana i ka maʻi diabetes type 2. ʻAʻole ia i ʻōlelo ʻia inā he maʻi ʻoe iā saxagliptin, metformin, a i ʻole nā ​​mea ʻē aʻe i loko o ka lāʻau.

Eia nā kūlana olakino kikoʻī e hoʻolilo i kēia lāʻau lapaʻau kūpono ʻole a i ʻole e koi i ka mālama kūikawā:

• Maʻi kīkī a i ʻole ka emi ʻana o ka hana kīkī
• Maʻi ake a i ʻole ka piʻi ʻana o nā enzyme ake
• Mōʻaukala o ka pancreatitis (ka mumū o ka pancreas)
• ʻAʻole hiki i ka naʻau ke hana pono e pono ai ka lāʻau lapaʻau
• Maʻi nui a i ʻole maʻi
• Mōʻaukala o ka lactic acidosis

E akahele nō hoʻi kāu kauka i ka kuhikuhi ʻana i kēia lāʻau lapaʻau inā ua hoʻonohonoho ʻia ʻoe no ke ʻoki a i ʻole kekahi mau kaʻina hana lapaʻau e pono ai ka waihoʻoluʻu, no ka mea, pono paha ʻoe e hooki i ka lāʻau lapaʻau i kēlā manawa.

Inā hāpai ʻoe, e hoʻolālā ana e hāpai, a i ʻole e hānai ana i ka waiū, e kūkākūkā me kāu kauka. ʻOiai ua hoʻohana ʻia ka metformin i kekahi manawa i ka wā hāpai, ʻaʻole i hoʻokumu ʻia ka palekana o ka saxagliptin i ka wā hāpai, no laila, ʻoi aku ka maikaʻi o nā lāʻau lapaʻau ʻē aʻe.

Nā inoa inoa o Saxagliptin a me Metformin

ʻO ka inoa inoa maʻamau no kēia hui pū ʻana o ka lāʻau lapaʻau ʻo Kombiglyze XR, ʻo ia ka mana hoʻokuʻu lōʻihi e lawe pinepine ai ʻoe i hoʻokahi manawa i ka lā. Aia kekahi mana hoʻokuʻu maʻamau e lawe ʻia i ʻelua manawa i ka lā.

Hiki nō hoʻi iā ʻoe ke ʻike i nā mana generic o kēia hui pū ʻana, aia nā mea hana like akā hana ʻia e nā hui lāʻau lapaʻau like ʻole. He kūpono nō hoʻi nā mana generic e like me nā lāʻau lapaʻau inoa inoa a pinepine ke kumu kūʻai.

Hiki i kāu hale kūʻai lāʻau lapaʻau ke pani i kahi mana generic ke ʻole kāu kauka e noi pono i ka inoa inoa. He mea maʻamau a palekana kēia - mau nō nā mea hana a me ka pono.

Nā koho ʻē aʻe o Saxagliptin a me Metformin

Inā ʻaʻole hana maikaʻi kēia hui pū ʻana no ʻoe a i ʻole ke kumu o nā hopena ʻaoʻao pilikia, aia kekahi mau lāʻau lapaʻau ʻē aʻe. Hiki i kāu kauka ke kōkua iā ʻoe e ʻimi i ka lāʻau lapaʻau kūpono a i ʻole ka hui pū ʻana e hana maikaʻi loa no kāu kūlana.

ʻO nā hui ʻē aʻe o ka DPP-4 inhibitor a me ka metformin e komo pū ana me sitagliptin a me metformin (Janumet) a i ʻole linagliptin a me metformin (Jentadueto). Hana like kēia mau mea akā ʻoi aku ka maikaʻi o ka ʻae ʻia e kekahi poʻe.

Inā ʻaʻole hiki iā ʻoe ke lawe i ka metformin ma muli o nā pilikia o ka puʻupaʻa a i ʻole nā hopena ʻaoʻao, hiki i kāu kauka ke kuhikuhi i ka saxagliptin wale nō a i ʻole e hui pū me nā lāʻau lapaʻau diabetes ʻē aʻe e like me ka insulin a i ʻole SGLT2 inhibitors.

No ka poʻe makemake i nā lāʻau lapaʻau injectable, hiki i nā mea hoʻokipa GLP-1 receptor e like me semaglutide a i ʻole liraglutide ke lilo i mau koho maikaʻi loa e hāʻawi pinepine i ka mana maikaʻi o ke kō koko a hiki ke kōkua i ka pohō kaumaha.

ʻOi aku ka maikaʻi o Saxagliptin a me Metformin ma mua o Sitagliptin a me Metformin?

ʻO Saxagliptin a me metformin (Kombiglyze) a me sitagliptin a me metformin (Janumet) he mau lāʻau lapaʻau like loa e hana ana ma nā ʻano like. He mau DPP-4 inhibitors lākou i hui pū ʻia me ka metformin, a hōʻike ka noiʻi he like ka pono i ka hoʻohaʻahaʻa ʻana i nā pae kō koko.

ʻO ke koho ma waena o kēia mau lāʻau lapaʻau e pili pinepine ana i nā mea pilikino e like me nā hopena ʻaoʻao, ka maʻalahi o ka dosing, ke kumukūʻai, a me ka uhi ʻinikua. ʻAe kekahi poʻe i kekahi ma mua o kekahi, ʻoiai ka hapa nui o nā kānaka e hana maikaʻi me kekahi koho.

E noʻonoʻo kāu kauka i kou kūlana olakino kikoʻī, nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, a me kāu mau makemake pilikino i ka wā e hoʻoholo ai ma waena o kēia mau koho. Ua manaʻo ʻia lāua he palekana a me ka maikaʻi o nā lāʻau lapaʻau laina mua no ka maʻi diabetes type 2.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Saxagliptin a me Metformin

Q1. Palekana ʻo Saxagliptin a me Metformin no ka poʻe me ka maʻi puʻuwai?

Ma keʻano laulā, ua manaʻo ʻia kēia hui ʻana he palekana no ka poʻe me ka maʻi puʻuwai, a hiki i ka metformin ke hāʻawi i kekahi mau pōmaikaʻi pale puʻuwai. Eia naʻe, makemake kāu kauka e nānā pono iā ʻoe inā he puʻuwai ʻoe a i ʻole nā maʻi puʻuwai koʻikoʻi ʻē aʻe.

ʻAʻole maʻamau ka lāʻau lapaʻau i nā pilikia o ka naʻau i nā kānaka olakino, akā he mea nui e haʻi i kāu kauka e pili ana i nā maʻi o ka naʻau āu e loaʻa nei. Hiki iā lākou ke hoʻololi i kāu mahele lāʻau a i ʻole ke koho i nā lāʻau lapaʻau ʻē aʻe inā loaʻa iā ʻoe ka maʻi puʻuwai holomua.

Q2. He aha kaʻu e hana ai inā ua hoʻohana hewa au i ka Saxagliptin a me Metformin?

Inā ua lawe hewa ʻoe i ka nui o kēia lāʻau lapaʻau, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau make, ʻoiai inā maikaʻi ʻoe. ʻO ka lawe ʻana i ka nui o ka metformin hiki ke alakaʻi i kahi maʻi koʻikoʻi i kapa ʻia ʻo ka lactic acidosis, e koi ana i ka mālama olakino koke.

E nānā i nā hōʻailona e like me ka ʻeha ʻiʻo maʻamau ʻole, ka pilikia o ka hanu ʻana, ka ʻeha o ka ʻōpū, ka ʻūlū, a i ʻole ka manaʻo nāwaliwali loa. Mai kali i nā hōʻailona e ʻike ʻia ma mua o ka ʻimi ʻana i ke kōkua - e kelepona koke i kāu kauka inā ua lawe ʻoe i ka nui ma mua o ka mea i kauoha ʻia.

Q3. He aha kaʻu e hana ai inā ua hala au i kahi mahele lāʻau o Saxagliptin a me Metformin?

Inā ua hala ʻoe i kahi mahele lāʻau, e lawe koke iā ia ke hoʻomanaʻo ʻoe, akā inā ʻaʻole kokoke i kāu mahele lāʻau i hoʻonohonoho ʻia. Inā kokoke i ka manawa no kāu mahele lāʻau e hiki mai ana, e lele i ka mea i hala a e hoʻomau me kāu papa manawa maʻamau.

Mai lawe ʻelua mahele lāʻau i ka manawa hoʻokahi e hoʻoponopono ai i kahi mahele lāʻau i hala, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao. Inā poina pinepine ʻoe i nā mahele lāʻau, e noʻonoʻo e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole ka hoʻohana ʻana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e noho ma ke ala.

Q4. I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Saxagliptin a me Metformin?

Pono ʻoe e hooki i ka lawe ʻana i kēia lāʻau lapaʻau ma lalo o ke alakaʻi a kāu kauka. He maʻi ola ka maʻi diabetes type 2, no laila pono ka hapa nui o nā kānaka e hoʻomau i ka lawe ʻana i nā lāʻau diabetes no ka manawa pau ʻole e mālama i ka maikaʻi o ke kōpaʻa koko.

Hiki i kāu kauka ke hoʻololi i kāu mau lāʻau lapaʻau i ka manawa ma muli o kāu pae kōpaʻa koko, nā hopena ʻaoʻao, a i ʻole nā loli i kou olakino. Inā hopohopo ʻoe e pili ana i ka lawe ʻana i ka lāʻau lapaʻau no ka wā lōʻihi, e kūkākūkā i kou mau manaʻo me kāu kauka - hiki iā lākou ke kōkua iā ʻoe e hoʻomaopopo i nā pōmaikaʻi a me ka hoʻoponopono ʻana i nā hopohopo.

Nīnau 5. Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Saxagliptin a me Metformin?

Hiki iā ʻoe ke inu i ka waiʻona i kekahi manawa, me ka liʻiliʻi, i ka wā e lawe ana i kēia lāʻau lapaʻau, akā he mea nui e makaʻala. Hiki i ka waiʻona ke hoʻonui i kou pilikia o ka loaʻa ʻana o ka lactic acidosis, ʻoiai inā inu nui ʻoe a i ʻole inu nui.

I ka wā e inu ai ʻoe, e inu i ka waiʻona me ka meaʻai a kaupalena iā ʻoe iho i hoʻokahi inu i kēlā me kēia lā inā he wahine ʻoe a i ʻole ʻelua mau inu i kēlā me kēia lā inā he kāne ʻoe. E kūkākūkā mau i kāu ʻai ʻana i ka waiʻona me kāu kauka, no ka mea, hiki iā lākou ke hāʻawi i ke alakaʻi pilikino e pili ana i kou olakino holoʻokoʻa.