He aha ʻo Selegiline: Nā Hoʻohana, Nā Ana, Nā ʻAoʻao ʻino a me nā mea hou aku

He lāʻau lapaʻau ʻo Selegiline e kōkua ana i ka mālama ʻana i nā hōʻailona o ka maʻi Parkinson ma ka pale ʻana i ka dopamine i kou lolo. Hana ʻokoʻa kēia lāʻau lapaʻau mai nā lāʻau lapaʻau ʻē aʻe o Parkinson no ka mea e ālai ana i kahi enzyme e wāwahi ana i ka dopamine, ka mea kemika lolo āu e pono ai no ka neʻe maʻalahi a me ka hoʻonohonoho.

Hiki i kāu kauka ke kuhikuhi iā selegiline ke hana ʻole kāu lāʻau lapaʻau Parkinson i kēia manawa e like me ka mea i hoʻohana ʻia. Manaʻo ʻia he lāʻau lapaʻau kākoʻo e hiki ke kōkua i ka hoʻolōʻihi i nā pōmaikaʻi o kāu lāʻau lapaʻau nui, e hāʻawi ana iā ʻoe i nā hola maikaʻi hou aʻe i ka lā.

He aha ʻo Selegiline?

No ka hui ʻo Selegiline o nā lāʻau lapaʻau i kapa ʻia ʻo MAO-B inhibitors, ʻo ia hoʻi e ālai ana i kahi enzyme kikoʻī i kou lolo i kapa ʻia ʻo monoamine oxidase B. Hoʻopau maʻamau kēia enzyme i ka dopamine, akā ke loaʻa iā ʻoe ka maʻi Parkinson, ua loaʻa iā ʻoe ka dopamine liʻiliʻi ma mua o kāu e pono ai.

E noʻonoʻo iā selegiline ma ke ʻano he pale pale no kāu dopamine i koe. Ma ka ālai ʻana i ka enzyme e luku ai i ka dopamine, ʻoi aku ka nui o kēia mea kemika lolo nui e loaʻa ana e kōkua i ka mālama ʻana i kāu neʻe ʻana a me ka hōʻemi ʻana i nā haʻalulu.

Hele mai ka lāʻau lapaʻau i nā papa maʻamau a me nā papa e hoʻoheheʻe ʻia ma ka waha e hoʻoheheʻe ʻia ma kou alelo. E koho kāu kauka i ke ʻano maikaʻi loa e pili ana i kāu mau pono kikoʻī a me ka maikaʻi o kou ale ʻana i nā pila.

No ke aha e hoʻohana ʻia ai ʻo Selegiline?

Hoʻohana nui ʻia ʻo Selegiline e mālama i ka maʻi Parkinson, ʻoi loa ke ʻole i mālama ʻia kāu mau hōʻailona e levodopa a me carbidopa wale nō. Kōkua ia i ka mālama ʻana i nā hōʻailona kaʻa e like me nā haʻalulu, ka ʻoʻoleʻo, a me ka neʻe lohi e paʻakikī ai nā hana i kēlā me kēia lā.

Hiki i kāu kauka ke hoʻohui iā selegiline i kāu hoʻolālā lapaʻau ke hoʻomaka ʻoe e ʻike i nā manawa

I kekahi manawa, kuhikuhi nā kauka i ka selegiline i nā pae mua o ka maʻi Parkinson. I kēia mau hihia, hiki iā ia ke kōkua i ka hoʻolohi ʻana i ka holomua o nā hōʻailona a hoʻopaneʻe i ka pono no nā lāʻau ikaika e like me ka levodopa.

Hiki i ka lāʻau lapaʻau ke kōkua i ka hōʻemi ʻana i nā loli i kāu mau hōʻailona i ka lā. Nui ka poʻe me ka maʻi Parkinson e ʻike i kā lākou mau hōʻailona e loli nui ana mai kēlā me kēia hola, a hiki i ka selegiline ke kōkua i ka hoʻomaʻemaʻe ʻana i kēia mau piʻi a me nā iho.

Pehea e hana ai ʻo Selegiline?

Hana ʻo Selegiline ma ka pale ʻana i ka MAO-B, kahi enzyme e wāwahi i ka dopamine i kou lolo. Ke loaʻa iā ʻoe ka maʻi Parkinson, make mālie nā pūnaewele lolo e hana ana i ka dopamine, no laila ʻo ka pale ʻana i ka dopamine i koe iā ʻoe e lilo i mea nui no ka mālama ʻana i nā hōʻailona.

Ua manaʻo ʻia kēia lāʻau lapaʻau he ikaika iki i nā lāʻau lapaʻau Parkinson. ʻAʻole ia e like me ka levodopa, i kapa pinepine ʻia ʻo ke kūlana gula, akā ʻoi aku ka pahuhopu a hiki ke hāʻawi i ka hōʻoluʻolu hōʻailona me nā hopena ʻaoʻao liʻiliʻi.

He mau lā ka hopena pale o ka selegiline ma hope o kou lawe ʻana. ʻO ia hoʻi, noho paʻa ka enzyme ʻoiai ma hope o ka haʻalele ʻana o ka lāʻau lapaʻau i kou kahe koko, e hāʻawi ana i nā pōmaikaʻi lōʻihi ma mua o kekahi mau lāʻau Parkinson ʻē aʻe.

ʻAʻole like me kekahi mau lāʻau lapaʻau Parkinson e pani ana i ka dopamine nalowale, kōkua ʻo selegiline i ka mālama ʻana i ka hana dopamine maoli o kou kino. Hiki i kēia ala ke ʻoluʻolu i kāu ʻōnaehana a hiki ke kumu i nā pilikia liʻiliʻi i ka manawa.

Pehea wau e lawe ai i ka Selegiline?

E lawe i ka selegiline e like me ke kauoha a kāu kauka, maʻamau hoʻokahi a ʻelua paha i ka lā me ka ʻole o ka meaʻai. ʻO ka maʻamau hoʻomaka ʻana he 5mg ʻelua i ka lā, lawe ʻia me ka ʻaina kakahiaka a me ka ʻaina awakea e pale ai i nā pilikia hiamoe.

Inā ʻoe e lawe ana i nā papa e hoʻoheheʻe ʻia i ka waha, e kau iā lākou ma kou alelo a e hoʻoheheʻe loa lākou. Mai nau, ʻoki, a ale paha i kēia mau papa holoʻokoʻa, no ka mea, hiki i kēia ke hoʻopilikia i ka hana maikaʻi o ka lāʻau lapaʻau.

He mea nui ka manawa me ka selegiline no ka mea hiki iā ia ke hoʻopilikia i ka hiamoe inā lawe ʻia i ka hopena o ka lā. E lawe i kāu mahele hope loa ma mua o ka hola 2 PM e pale ai i ka insomnia a i ʻole ka ʻoluʻolu ʻole i ka wā e moe ai.

Hiki iā ʻoe ke lawe i ka selegiline me ka ʻole o ka meaʻai, akā ʻo ka lawe ʻana me kahi mea ʻai liʻiliʻi e kōkua paha i ka hōʻemi ʻana i ka ʻōpū. E pale i ka lawe ʻana me nā meaʻai nui i kiʻekiʻe i nā meaʻai waiwai tyramine e like me nā paʻakai kahiko, nā ʻiʻo i hoʻōla ʻia, a i ʻole nā ​​huahana fermented.

Mai hooki koke i ka lawe ʻana i ka selegiline me ka ʻole e kamaʻilio mua me kāu kauka. Hiki ke ʻino koke nā hōʻailona o Parkinson inā e hoʻōki koke ʻoe i ka lāʻau.

Pehea ka lōʻihi e lawe ai au i ka Selegiline?

Lawe ka hapa nui o ka poʻe me ka maʻi Parkinson i ka selegiline no nā makahiki he nui ma ke ʻano he ʻāpana o kā lākou hoʻolālā lapaʻau lōʻihi. ʻOi aku ka maikaʻi o ka lāʻau lapaʻau ke lawe ʻia me ka hoʻomau ʻana i ka manawa, e kōkua ana i ka mālama ʻana i nā pae dopamine paʻa i kou lolo.

E nānā mau kāu kauka i ka maikaʻi o ka hana ʻana o ka selegiline iā ʻoe ma o nā koho ukali. E loiloi lākou inā ua mālama maikaʻi ʻia kāu mau hōʻailona a inā pono e hoʻoponopono i kāu hoʻolālā lapaʻau.

Pono paha kekahi poʻe e lawe i ka selegiline no ke koena o ko lākou ola, ʻoiai inā e hoʻomaikaʻi nui ia i ko lākou maikaʻi o ke ola a me ka mana o ka hōʻailona. He mea maʻamau kēia a manaʻo ʻia no nā maʻi maʻi e like me ka maʻi Parkinson.

Aia nō hoʻi ka lōʻihi o ka mālama ʻana i ke ʻano o kou maʻi a inā pono nā lāʻau lapaʻau ʻē aʻe. Hiki i kāu kauka ke hoʻohui i nā lāʻau lapaʻau ʻē aʻe a i ʻole e hoʻoponopono i kāu mahele selegiline i ka loli ʻana o kāu mau pono i ka manawa.

He aha nā hopena ʻaoʻao o ka Selegiline?

E like me nā lāʻau lapaʻau a pau, hiki i ka selegiline ke hana i nā hopena ʻaoʻao, ʻoiai ua ʻae maikaʻi ka poʻe he nui. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a hoʻomaikaʻi pinepine i ka hoʻoponopono ʻana o kou kino i ka lāʻau.

Eia nā hopena ʻaoʻao āu e ʻike ai, e hoʻomaka ana me nā mea maʻamau:

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• Ka luaʻi a me ka ʻōpū ʻeha
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• Ka wili a i ʻole ka māmā
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• Ka pilikia o ka hiamoe a i ʻole nā moeʻuhane ola
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• Ka waha maloʻo
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• Ke poʻo
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• Ka huikau a i ʻole nā manaʻo
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• Hoʻonui i nā neʻe ʻana i ka makemake ʻole
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ʻO kēia mau hopena ʻaoʻao maʻamau e mae maʻamau i loko o kekahi mau pule i ka wā e maʻa ai kou kino i ka lāʻau. Inā mau lākou a lilo i mea hoʻonāukiuki, hiki i kāu kauka ke hoʻoponopono i kāu mahele a i ʻole ka manawa e kōkua ai.

Hiki i nā hopena ʻaoʻao koʻikoʻi akā kakaʻikahi ke komo i nā loli nui o ke ʻano, ka ʻeha o ka umauma, a i ʻole ka piʻi koke ʻana o ke koko. Pono kēia mau mea i ka lāʻau lapaʻau koke a ʻoi aku ka nui o ka hiki ke hana inā ʻoe e ʻai i kekahi mau meaʻai a i ʻole e lawe i nā lāʻau ʻē aʻe e launa pū me ka selegiline.

ʻIke kekahi poʻe i ka mea i kapa ʻia ʻo ka

E haʻi mau i kāu kauka e pili ana i nā lāʻau lapaʻau a pau āu e lawe nei, me nā lāʻau lapaʻau i kūʻai ʻia ma luna o ka pā, nā mea hoʻohui, a me nā lāʻau lapaʻau. ʻO nā huahana i ʻike ʻia he palekana e like me St. John's wort hiki ke launa pū me ka selegiline.

Nā inoa inoa o Selegiline

Loaʻa ʻo Selegiline ma lalo o nā inoa inoa like ʻole, ʻo Eldepryl ka mea i ʻike nui ʻia. ʻO kēia ka inoa inoa mua no ke ʻano papa maʻamau o ka selegiline i kākau ʻia e nā kauka no nā makahiki he nui.

ʻO Zelapar kekahi inoa inoa, no nā papa e hoʻoheheʻe ʻia ma ka waha e hoʻoheheʻe ʻia ma kou alelo. He maʻalahi kēia mau papa no ka poʻe i pilikia i ka ʻai ʻana i nā pila ma muli o ka maʻi o Parkinson.

Loaʻa nā mana generic o ka selegiline a hana like me nā mana inoa inoa. Hiki i kāu kauka lapaʻau ke haʻi iā ʻoe i ka mana āu e loaʻa nei a pane i nā nīnau e pili ana i nā ʻokoʻa ma waena o nā hōʻailona.

ʻO ka mea hana ikaika ka mea like me ka inoa inoa, no laila ʻo ka hoʻololi ʻana ma waena o nā mea hana like ʻole ʻaʻole ia e pili i ka maikaʻi o ka lāʻau lapaʻau iā ʻoe.

Nā koho ʻē aʻe o Selegiline

Inā ʻaʻole kūpono ka selegiline iā ʻoe, hiki i kekahi mau lāʻau lapaʻau ʻē aʻe ke kōkua i ka mālama ʻana i nā hōʻailona o ka maʻi o Parkinson. Hiki i kāu kauka ke noʻonoʻo i ka rasagiline, he mea hoʻopaʻa MAO-B hou e hana like me ka selegiline akā ʻaʻole paha he hopena ʻaoʻao.

Hana nā agonists Dopamine e like me pramipexole a i ʻole ropinirole i nā mea like ʻole ma ka hoʻoulu pololei ʻana i nā mea hoʻokipa dopamine i kou lolo. Hiki i kēia mau lāʻau lapaʻau ke lilo i nā koho ʻē aʻe, ʻoi aku hoʻi i nā pae mua o ka maʻi o Parkinson.

ʻO nā mea hoʻopaʻa COMT e like me entacapone a i ʻole tolcapone kekahi koho e kōkua i ka hoʻolōʻihi i nā hopena o levodopa. Hana kēia mau mea ma ka pale ʻana i kahi enzyme ʻokoʻa e wāwahi i ka levodopa ma mua o ka hiki ʻana i kou lolo.

Hiki nō i kāu kauka ke noʻonoʻo i ka amantadine, he nui nā ala e kōkua ai i nā hōʻailona o Parkinson a hiki ke kōkua nui i ka hōʻemi ʻana i nā neʻe ʻana i hana ʻia e nā lāʻau ʻē aʻe.

Aia ka koho maikaʻi loa ma muli o kāu mau hōʻailona kikoʻī, nā lāʻau ʻē aʻe āu e lawe nei, a pehea e pane ai kou kino i nā lāʻau lapaʻau like ʻole. E hana pū kāu kauka me ʻoe e ʻimi i ka hui pū ʻana.

Ua ʻoi aku ka maikaʻi o Selegiline ma mua o Rasagiline?

ʻO Selegiline a me rasagiline nā mea pale MAO-B e hana ana ma nā ʻano like, akā he mau ʻokoʻa nui ko lākou. He lāʻau hou ʻo Rasagiline i hiki ke hoʻoulu i nā hopena ʻaoʻao liʻiliʻi a me nā pilina lāʻau ma mua o selegiline.

Ua hoʻohana ʻia ʻo Selegiline no ka lōʻihi a ʻoi aku ka nui o ka noiʻi e kākoʻo ana i kona pono, ʻoiai ke hui pū ʻia me levodopa. Loaʻa nō hoʻi ia i nā ʻano like ʻole, me nā papa e hoʻoheheʻe ʻia i ka waha i ʻike ʻia e kekahi poʻe he maʻalahi ke lawe.

ʻAʻole paha e hoʻoulu ʻo Rasagiline i nā pilikia hiamoe no ka mea ʻaʻole ia e wāwahi i nā mea e like me ka amphetamine i loko o kou kino. ʻO kēia ka mea e koho maikaʻi ai no ka poʻe e ʻike ana i nā hopena stimulant.

ʻAʻole maikaʻi kekahi lāʻau lapaʻau ma mua o kekahi. Aia ke koho ma waena o lākou ma muli o kāu pane pilikino, ka ʻaoʻao hopena, a me nā lāʻau ʻē aʻe āu e lawe nei.

E noʻonoʻo kāu kauka i nā mea e like me kou makahiki, ka hana o ka puʻupaʻa, nā kūlana olakino ʻē aʻe, a me nā pane lāʻau mua i ka wā e hoʻoholo ai ma waena o kēia mau koho ʻelua.

Nā nīnau i nīnau pinepine ʻia e pili ana iā Selegiline

Q1. He palekana ʻo Selegiline no ka poʻe me ka maʻi puʻuwai?

He palekana ʻo Selegiline no ka poʻe me ka maʻi puʻuwai, akā e nānā pono kāu kauka iā ʻoe inā he maʻi cardiovascular kou. Hiki i ka lāʻau lapaʻau ke hoʻololi i ke koko a i ʻole ka puʻuwai, ʻoiai ke hoʻomaka ʻana i ka lāʻau lapaʻau.

Inā he maʻi puʻuwai kou, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi mahele haʻahaʻa a hoʻonui mālie. Makemake lākou e ʻike iā ʻoe pinepine i nā mahina mua e nānā i ke ʻano o ka pane ʻana o kou puʻuwai i ka lāʻau.

E haʻi koke i kāu kauka inā loaʻa iā ʻoe ka ʻeha o ka umauma, ka puʻuwai ʻole, a i ʻole ka pōkole o ka hanu i ka wā e lawe ana i ka selegiline. Hiki i kēia mau hōʻailona ke hōʻike i ka pono o kou maʻi puʻuwai i ka nānā ʻana a i ʻole nā hoʻoponopono lapaʻau.

Q2. He aha kaʻu e hana ai inā ua hoʻohana hewa au i ka nui o ka Selegiline?

Inā lawe hewa ʻoe i ka nui o ka selegiline, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena mana ʻawaʻawa, ʻoiai inā maikaʻi ʻoe. ʻAʻole paha e ʻike koke ʻia nā hōʻailona overdose akā hiki ke komo i ka ʻeha poʻo nui, ka ʻeha o ka umauma, a i ʻole nā loli weliweli i ke koko.

Mai ho'āʻo e hana iā ʻoe iho e luaʻi a i ʻole e lawe i nā lāʻau ʻē aʻe e kūʻē i ka overdose. Akā, e hōʻiliʻili i kāu ʻōmole lāʻau a hele i ka lumi pilikia kokoke loa inā ʻōlelo kāu kauka.

E mālama i kahi papa inoa o kāu mau lāʻau lapaʻau a pau me ʻoe, me ka mahele pololei o ka selegiline āu i lawe ai. E kōkua kēia ʻike i nā poʻe loea lapaʻau e hāʻawi i ka mālama maikaʻi loa inā pono ʻoe i ka lāʻau lapaʻau.

Q3. He aha kaʻu e hana ai inā ua hala au i kahi mahele o Selegiline?

Inā hala ʻoe i kahi mahele o ka selegiline, e lawe koke iā ia ke hoʻomanaʻo ʻoe, ke ʻole ua awakea a ahiahi paha. ʻO ka lawe ʻana i ka selegiline i ka hopena o ka lā hiki ke hoʻopilikia i kāu hiamoe.

Inā ua hala mua i ka hola 2 PM i ka wā e hoʻomanaʻo ai ʻoe i kāu mahele i hala, e lele iā ia a lawe i kāu mahele aʻe i ka manawa maʻamau. Mai pāpālua i nā mahele e hoʻopiha ai i ka mea i hala, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao.

ʻAʻole e hōʻino iā ʻoe ka hala ʻana i kahi mahele i kekahi manawa, akā e hoʻāʻo e mālama i kahi papa manawa kūlike no ka mana hōʻailona maikaʻi loa. E noʻonoʻo e hoʻonohonoho i nā mea hoʻomanaʻo kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e hoʻomanaʻo.

Q4. I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana i ka Selegiline?

Mai hooki koke i ka lawe ʻana i ka selegiline me ka ʻole e kamaʻilio mua me kāu kauka. E ʻoi aku paha kou mau hōʻailona Parkinson inā e hooki koke ʻoe i ka lāʻau lapaʻau, a e ʻike paha ʻoe i nā hopena e like me ka haʻalele ʻana.

E kōkua kāu kauka iā ʻoe e hoʻemi mālie i kāu mahele i nā pule he nui inā pono e hooki i ka selegiline. Kōkua kēia hana lohi e pale i ka hoʻi koke ʻana o nā hōʻailona a hiki i kou kino ke hoʻoponopono.

ʻO ka hoʻoholo e hooki i ka selegiline e hana maʻamau i ka wā e lilo ai nā hopena ʻaoʻao i mea pilikia loa a i ʻole i ka wā e lilo ai nā lāʻau lapaʻau ʻē aʻe i mea kūpono no kou maʻi. E hana pū kāu kauka me ʻoe e ʻimi i ka mea ʻē aʻe maikaʻi loa ma mua o ka hooki ʻana i ka selegiline.

Q5. Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Selegiline?

ʻOi aku ka maikaʻi e kaupalena i ka inu ʻana i ka waiʻona i ka wā e lawe ana i ka selegiline, no ka mea, hiki i ka waiʻona ke hoʻonui i kekahi mau hopena ʻaoʻao e like me ka ʻūlū a me ka huikau. He maikaʻi nā mea liʻiliʻi o ka waiʻona, akā e pale i ka inu nui ʻana a i ʻole ka inu ʻana i ka binge.

E makaʻala loa i ka waina ʻulaʻula a me ka pia, no ka mea, aia i loko o kēia mau mea ka tyramine, hiki ke launa pū me ka selegiline e hoʻoulu i ka piʻi ʻana o ke koko. ʻO nā ʻuhane maʻemaʻe e like me ka vodka a i ʻole ka gin he mau koho palekana inā koho ʻoe e inu.

E kamaʻilio me kāu kauka e pili ana i kāu mau hana waiʻona i hiki iā lākou ke hāʻawi iā ʻoe i ka ʻōlelo aʻo pilikino. Hiki iā lākou ke ʻōlelo e pale loa i ka waiʻona inā e ʻike ana ʻoe i kekahi mau hopena ʻaoʻao a i ʻole e lawe ana i nā lāʻau lapaʻau ʻē aʻe e launa pū me ka waiʻona.