He aha ʻo Talimogene Laherparepvec: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Talimogene laherparepvec kahi lapaʻau maʻi maʻi e hoʻohana ana i kahi maʻi herpes i hoʻololi ʻia e hakakā i ka melanoma. Hana kēia lāʻau lapaʻau hou ma ka hoʻopili ʻana i nā sela maʻi a kōkua i kāu ʻōnaehana pale e ʻike a luku iā lākou me ka maikaʻi.

Hiki paha iā ʻoe ke manaʻo ua piha ʻoe i ka ʻike e pili ana i kēia lapaʻau, a he mea maopopo loa ia. E hele kākou i nā mea a pau e pono ai ʻoe e ʻike e pili ana i kēia lāʻau lapaʻau ma nā huaʻōlelo maʻalahi a maʻalahi i hiki iā ʻoe ke manaʻoʻiʻo i kāu huakaʻi lapaʻau.

He aha ʻo Talimogene Laherparepvec?

ʻO Talimogene laherparepvec kahi lāʻau lapaʻau maʻi oncolytic, ʻo ia hoʻi he lapaʻau e hoʻohana ana i nā maʻi e hakakā i ka maʻi maʻi. Aia i loko o kēia lāʻau lapaʻau kahi maʻi herpes simplex i hoʻololi ʻia i hoʻolālā ʻia e palekana no ka mālama ʻana i ka maʻi maʻi.

He ʻokoʻa ka maʻi i loko o kēia lāʻau lapaʻau mai ka herpes e hana ai i nā maʻi anu. Ua hoʻololi pono nā kānaka ʻepekema iā ia i hiki ke ulu wale i loko o nā sela maʻi, ʻaʻole nā sela olakino. Ke hoʻopili ka maʻi i nā sela melanoma, e wāwahi ia iā lākou a hoʻokuʻu i nā mea e makaʻala ai i kāu ʻōnaehana pale e hoʻouka i ka maʻi.

Hōʻike kēia lapaʻau i kahi ala hou i ka mālama ʻana i ka maʻi i kapa ʻia ʻo immunotherapy. Ma kahi o ka hoʻohana ʻana i nā kemika a i ʻole ka radiation e pepehi pololei i nā sela maʻi, hana ia me ka ʻōnaehana pale kūlohelohe o kou kino e hakakā i ka maʻi.

No ke aha e hoʻohana ʻia ai ʻo Talimogene Laherparepvec?

Ua ʻae ʻia kēia lāʻau lapaʻau no ka mālama ʻana i ka melanoma i laha i kou mau lymph nodes a i ʻole nā ʻāpana ʻē aʻe o kou ʻili akā ʻaʻole i hiki i kou mau ʻōpū o loko. E ʻōlelo wale kāu kauka i kēia lapaʻau inā ʻaʻole hiki ke wehe ʻia kāu melanoma me ke ʻoki.

Hana maikaʻi ka lapaʻau ke waiho ʻia ka maʻi ma nā wahi i hiki ke hoʻokomo pololei ʻia. E loiloi pono kāu oncologist inā ʻo kāu ʻano a me ke kahua o ka melanoma e lilo ʻoe i moho maikaʻi no kēia lāʻau lapaʻau.

I kekahi manawa, hiki i nā kauka ke noʻonoʻo i kēia lapaʻau no nā ʻano maʻi ʻaʻai ʻē aʻe i nā hoʻokolohua lapaʻau, akā ʻo ka melanoma ka mea nui i ʻae ʻia. E kūkākūkā kāu hui lapaʻau inā kūpono kēia i kou kūlana.

Pehea e hana ai ʻo Talimogene Laherparepvec?

Hana kēia lāʻau lapaʻau ma o kahi kaʻina hana ʻelua ʻanuʻu i ʻokoʻa loa mai nā lāʻau lapaʻau maʻi maʻamau. ʻO ka mea mua, hoʻopili ka maʻi i hoʻololi ʻia i kāu mau sela melanoma a hoʻoulu iā lākou e haki, kahi e luku pololei ai i kekahi mau sela maʻi.

ʻO ka lua o ka ʻanuʻu kahi e waiho ai ka mana maoli. Ke haki nā sela maʻi, hoʻokuʻu lākou i nā ʻāpana o lākou iho me nā mea e hana ana e like me nā bele alarm no kāu ʻōnaehana pale. Kōkua kēia i nā pale kūlohelohe o kou kino e ʻike i nā sela maʻi ma ke ʻano he mea hoʻoweliweli e pono ai lākou e hoʻouka.

E noʻonoʻo e like me ke aʻo ʻana i kāu ʻōnaehana pale e lilo i mea hakakā maʻi maikaʻi aʻe. Hoʻololi ke ʻano o ka lapaʻau i kāu maʻi i kahi kahua hoʻomaʻamaʻa kahi e aʻo ai kāu mau sela pale e ʻike a luku i nā sela melanoma ma kou kino.

Ua manaʻo ʻia he lāʻau lapaʻau i manaʻo ʻia no ka mea e ʻimi pono ana i nā sela maʻi me ka waiho ʻana i kāu mau sela olakino wale nō. ʻAʻole hiki i ka maʻi i hoʻololi ʻia ke hana hou i nā sela maʻamau a olakino, kahi e palekana ai ma mua o ka hoʻohana ʻana i kahi maʻi maʻamau.

Pehea wau e lawe ai iā Talimogene Laherparepvec?

Hāʻawi ʻia kēia lāʻau lapaʻau ma ke ʻano he injection pololei i loko o kāu mau maʻi melanoma, ʻaʻole ma ke ʻano he pill a i ʻole ma o IV. E hoʻohana kāu kauka i kahi nila liʻiliʻi e hoʻokomo i ka lāʻau lapaʻau i loko o nā wahi maʻi i hiki ke kiʻi ʻia me ka palekana.

E loaʻa iā ʻoe kāu lapaʻau mua ma ke keʻena o kāu kauka a i ʻole ke kikowaena lapaʻau. ʻO ke kaʻina hana injection ponoʻī e lawe maʻamau i kekahi mau minuke, ʻoiai paha e pono ʻoe e noho no ka nānā ʻana ma hope e hōʻoia e maikaʻi ana ʻoe.

E hoʻomaʻemaʻe maikaʻi kāu hui mālama ola i kahi e hoʻokomo ʻia ai ka lāʻau ma mua o kēlā me kēia lapaʻau. ʻAʻole pono ʻoe e hana i kekahi mea kūikawā e hoʻomākaukau ai, e like me ka ʻai ʻole ʻana a i ʻole ka lawe ʻana i nā lāʻau ʻē aʻe ma mua. E ʻaʻahu wale i nā lole ʻoluʻolu e maʻalahi ai ke komo ʻana i nā wahi e mālama ʻia nei.

Ma hope o ka hoʻokomo ʻana i ka lāʻau, e uhi kāu kauka i kahi i mālama ʻia me ka pā a i ʻole ka lole. E loaʻa iā ʻoe nā ʻōlelo kikoʻī e pili ana i ka mālama ʻana i ka wahi maʻemaʻe a maloʻo no nā lā e hiki mai ana.

Pehea ka lōʻihi e lawe ai au i ka Talimogene Laherparepvec?

Hoʻomaka maʻamau ka papa hana lapaʻau me ka hoʻokomo mua ʻana i ka lāʻau, a ma hope e hoʻokomo ʻia ka lāʻau ʻelua i ʻekolu pule ma hope. Ma hope o kēlā, e loaʻa iā ʻoe nā hoʻokomo ʻana i kēlā me kēia ʻelua pule no ʻeono mahina, akā hiki ke ʻokoʻa kēia ma muli o ke ʻano o kou pane ʻana.

E nānā pono kāu kauka i kou holomua i ka wā o ka lapaʻau. E nānā lākou i ke ʻano o ka pane ʻana o kāu mau maʻi ʻaʻai a me ke ʻano o kou hoʻomanawanui ʻana i nā hoʻokomo ʻana. Pono paha kekahi poʻe e mālama ʻia no nā mahina ʻeono, a ʻo nā mea ʻē aʻe e pau mua.

ʻO ka nui o nā hoʻokomo ʻana i ka lāʻau e pono ai ʻoe e hilinaʻi i nā mea he nui. Aia kēia mau mea i ka nui a me ka helu o kāu mau maʻi ʻaʻai, pehea lākou e pane ai i ka lapaʻau, a inā paha e ʻike ʻoe i nā hopena ʻaoʻao e pono ai ka hoʻoponopono ʻana i kāu papa hana.

E loiloi mau kāu hui lapaʻau inā he mea pono ka hoʻomau ʻana i ka lapaʻau iā ʻoe. E kaulike lākou i nā pōmaikaʻi e hiki mai ana me nā hopena ʻaoʻao āu e ʻike ai.

He aha nā hopena ʻaoʻao o Talimogene Laherparepvec?

ʻO ka hapa nui o nā kānaka e ʻike i kekahi mau hopena ʻaoʻao me kēia lapaʻau, akā hiki ke mālama ʻia a he manawa pōkole. ʻO nā hopena ʻaoʻao maʻamau e hana ʻia ma kahi i hoʻokomo ʻia ai ka lāʻau a me ka ʻeha, ka pehu, a me ka ʻulaʻula kahi i hāʻawi ʻia ai ka lāʻau.

Eia nā hopena ʻaoʻao āu e ʻike ai, a he mea nui e ʻike ʻo ka loaʻa ʻana o kēia mau hopena, ʻo ia hoʻi ke hana nei ka lapaʻau e like me ka mea i manaʻo ʻia:

• Ka luhi e mau ana no kekahi mau lā ma hope o kēlā me kēia pahu
• Ke anu a me ke kuni, ʻoi loa i loko o nā hola 24 mua
• Ka luaʻi ʻana a i ʻole ka manaʻo maikaʻi ʻole
• Ke poʻo e pane maikaʻi ana i ka hoʻomaha ʻeha ma luna o ka pāʻani
• ʻEha ʻiʻo e like me nā hōʻailona flu
• Nā hopena ma ka pūnaewele injection e like me ka ʻeha a i ʻole ke aloha

Hoʻomaikaʻi maʻamau kēia mau hōʻailona i loko o kekahi mau lā a pinepine e lilo i mea liʻiliʻi me nā lāʻau lapaʻau ma hope mai i ka wā e hoʻoponopono ai kou kino i ka lāʻau.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi e pono ai ka mālama olakino koke. E kelepona i kāu hui mālama olakino i kēia manawa inā e hoʻomohala ʻoe i nā hōʻailona flu koʻikoʻi, nā hōʻailona o ka maʻi ma ka pūnaewele injection, a i ʻole nā ​​hōʻailona maʻamau e pili ana iā ʻoe.

I nā manawa kakaʻikahi, hiki i kekahi poʻe ke hoʻomohala i kahi hopena immune e pili ana i nā ʻāpana ʻē aʻe o ko lākou kino. E nānā pono kāu kauka iā ʻoe no nā hōʻailona o kēia a e ʻike pehea e mālama ai inā e hana ia.

ʻO wai ka mea pono ʻole e lawe iā Talimogene Laherparepvec?

ʻAʻole kūpono kēia lapaʻau no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ka ʻōlelo ʻana. ʻAʻole hiki i nā poʻe me nā ʻōnaehana immune nāwaliwali loa ke loaʻa i kēia lapaʻau me ka palekana.

ʻAʻole pono ʻoe e loaʻa i kēia lāʻau inā hāpai ʻoe a i ʻole e hānai ana, no ka mea, ʻaʻole ʻike piha ʻia nā hopena i nā pēpē e ulu ana. E kūkākūkā kāu kauka i nā ʻano hana hoʻomalu hānau maikaʻi inā he makahiki hānau kāu.

Pono paha ka poʻe me nā maʻi maʻi, ʻoi loa nā maʻi herpes, e kali a hiki i ka pau ʻana o kēia mau mea ma mua o ka hoʻomaka ʻana i ka lapaʻau. Pono e lawa ka ikaika o kāu ʻōnaehana immune e mālama pono i ka lāʻau.

ʻAʻole paha he mau moho maikaʻi ka poʻe e lawe ana i nā lāʻau e hoʻopau nui i ka ʻōnaehana immune. Aia kēia i nā poʻe i loaʻa i nā mea lapaʻau organ a i ʻole e lawe ana i nā kiʻekiʻe kiʻekiʻe o nā steroids no nā kūlana ʻē aʻe.

E noʻonoʻo nō hoʻi kāu kauka inā ua laha aku kāu melanoma i nā ʻōkana o loko, no ka mea, ʻoi aku ka maikaʻi o kēia lapaʻau ke hiki ke hoʻokomo pololei ʻia nā ʻōpū.

Inoa Brand o Talimogene Laherparepvec

Kūʻai ʻia kēia lāʻau lapaʻau ma lalo o ka inoa brand ʻo Imlygic. Hiki paha iā ʻoe ke ʻike i kēia inoa ma kāu mau ʻōmole kauoha, nā palapala ʻinikua, a i ʻole nā palapala hoʻonohonoho lapaʻau.

ʻO Imlygic wale nō ka inoa brand no kēia lāʻau lapaʻau i loaʻa i kēia manawa. No ka mea he lapaʻau maʻi ʻaʻai kūikawā kēia, loaʻa wale nō ia ma o kekahi mau keʻena mālama ola i loaʻa ka ʻike me kēia ʻano lapaʻau.

Na kāu hui oncology e mālama i ka kauoha a me ka lawelawe ʻana iā Imlygic, no laila ʻaʻole pono ʻoe e kiʻi i kēia mai kahi hale kūʻai lāʻau maʻamau e like me nā lāʻau lapaʻau ʻē aʻe.

Nā Koho ʻē aʻe o Talimogene Laherparepvec

Nui nā koho lapaʻau ʻē aʻe no ka melanoma, ʻoiai e hana ʻokoʻa ana kēlā me kēia a kūpono paha no nā kūlana like ʻole. E noʻonoʻo kāu oncologist i kāu hihia kikoʻī i ke kūkākūkā ʻana i nā koho ʻē aʻe.

Hana nā lāʻau lapaʻau immunotherapy ʻē aʻe e like me pembrolizumab a i ʻole nivolumab ma ka pale ʻana i nā protein e pale ai i kāu ʻōnaehana pale mai ka hoʻouka ʻana i nā cell maʻi ʻaʻai. Hāʻawi ʻia kēia mau mea ma o nā infusions IV ma mua o ka hoʻokomo pololei ʻana i nā ʻōpū.

ʻO nā lapaʻau kuʻuna e like me ke ʻoki ʻana, ka radiation therapy, a i ʻole ka chemotherapy paha he mau koho e pili ana i kahi a me ke kahua o kāu melanoma. Loaʻa i kekahi poʻe nā hui pū ʻana o nā lapaʻau like ʻole no nā hopena maikaʻi loa.

ʻO nā lāʻau lapaʻau i manaʻo ʻia e pale i nā protein kikoʻī i nā cell maʻi ʻaʻai e hōʻike ana i kahi ala ʻē aʻe. ʻO kēia mau mea he mau pila i lawe ʻia i kēlā me kēia lā a hana maikaʻi no nā melanomas me kekahi mau loli genetic.

E wehewehe kāu hui mālama ola i nā koho ʻē aʻe e hana maikaʻi loa no kāu kūlana kikoʻī a kōkua iā ʻoe e hoʻomaopopo i nā pono a me nā pōʻino o kēlā me kēia koho.

ʻOi aku ka maikaʻi o Talimogene Laherparepvec ma mua o nā lapaʻau melanoma ʻē aʻe?

Hāʻawi kēia lapaʻau i nā pōmaikaʻi kūikawā no kekahi poʻe maʻi, akā inā he “ʻoi aku ka maikaʻi” e hilinaʻi ana i kou kūlana pilikino. ʻAʻole like me nā lapaʻau ʻōnaehana e pili ana i kou kino holoʻokoʻa, ua kuhikuhi pololei kēia lapaʻau i nā maʻi ʻaʻai i ka wā e hana ana i nā pane immune ākea.

No ka poʻe me ka melanoma hiki ke hoʻokomo pololei ʻia, hiki i kēia lapaʻau ke hana i nā hopena ʻaoʻao liʻiliʻi ma mua o kekahi mau immunotherapies ʻē aʻe. ʻO nā hopena ʻaoʻao pinepine i ka wahi a hiki ke mālama ʻia i ka hoʻohālikelike ʻana i nā lapaʻau e pili ana i kāu ʻōnaehana holoʻokoʻa.

Eia naʻe, hana wale kēia lapaʻau no ka melanoma ʻaʻole i laha i nā ʻōkana o loko. Hiki i nā immunotherapies ʻē aʻe a i ʻole nā lapaʻau i kuhikuhi ʻia ke kūpono inā ua laha ākea kāu maʻi ʻaʻai.

ʻO ka lapaʻau maikaʻi loa no ʻoe e hilinaʻi ana i nā mea he nui me ke kahua o kāu maʻi ʻaʻai, kahi, nā ʻano genetic, a me kou olakino holoʻokoʻa. E kōkua kāu oncologist iā ʻoe e kaupaona i kēia mau mea e hana i ka hoʻoholo maikaʻi loa no kou kūlana kikoʻī.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Talimogene Laherparepvec

He Palekana ʻo Talimogene Laherparepvec no ka poʻe me ka maʻi diabetes?

ʻAʻole e pale ʻakomi ka loaʻa ʻana o ka maʻi diabetes iā ʻoe mai ka loaʻa ʻana o kēia lapaʻau, akā pono kāu kauka e nānā pono iā ʻoe. Hiki i ka poʻe me ka maʻi diabetes ke loaʻa i nā pilikia liʻiliʻi o ka maʻi a i ʻole ka lohi o ka hoʻōla ʻana ma nā wahi injection.

E hana pū kāu hui mālama ola me ʻoe e mālama i kāu pae kō koko i ka wā o ka lapaʻau. Hiki i ka mālama maikaʻi ʻana i ka maʻi diabetes ke kōkua i ka hōʻemi ʻana i kou pilikia o nā pilikia a hoʻomaikaʻi i ka hiki o kou kino ke hoʻōla ma hope o nā injections.

He aha kaʻu e hana ai inā pili au i ka wahi injection?

Inā pili ʻoe i ka wahi i mālama ʻia, holoi pono i kou mau lima me ke kopa a me ka wai koke. Aia i loko o ka lāʻau lapaʻau kahi maʻi i hoʻololi ʻia, no laila ke kōkua nei ka maʻemaʻe maikaʻi i ka pale ʻana i kekahi pilikia theoretical o ka laha ʻana iā haʻi.

E pale i ka hoʻopā ʻana i kahi i hoʻokomo ʻia ai ka lāʻau me ka pono ʻole a e uhi ʻia me ka lole i hāʻawi ʻia e kāu hui mālama ola. Inā wehe ka lole a pulu paha, e hoʻokaʻaʻike i kāu kikowaena lapaʻau no ke alakaʻi ʻana i ka hoʻomaʻemaʻe pono a me ka uhi hou ʻana i ka wahi.

He aha kaʻu e hana ai inā e hala wau i kahi injection i hoʻonohonoho ʻia?

E hoʻokaʻaʻike i kāu hui mālama ola i ka wā hiki wawe inā e hala ʻoe i kahi lapaʻau i hoʻonohonoho ʻia. E kōkua lākou iā ʻoe e hoʻonohonoho hou a e hoʻoholo inā pono e hoʻololi i kāu hoʻolālā lapaʻau.

Mai hoʻāʻo e hoʻoponopono i nā lāʻau i hala ma ka hoʻonohonoho ʻana i nā lapaʻau kokoke loa. Pono kāu kauka e mālama i ka mamao kūpono ma waena o nā injections i mea e hana pono ai a palekana ka lapaʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Talimogene Laherparepvec?

Na kāu kauka e hoʻoholo i ka manawa e hooki ai i ka lapaʻau ma muli o ke ʻano o ka pane ʻana o kāu mau ʻōpū a me ka maikaʻi o kou ʻae ʻana i nā injections. Loaʻa ka lapaʻau i ka hapa nui o nā kānaka no ʻeono mahina, akā hiki ke ʻokoʻa kēia.

Hiki iā ʻoe ke hooki mua inā e nalowale loa kāu mau ʻōpū a i ʻole inā ʻike ʻoe i nā hopena ʻaoʻao e hoʻolilo i ka hoʻomau ʻana i ka lapaʻau i mea palekana ʻole. E nānā pono kāu hui mālama ola i kāu holomua a e kūkākūkā i nā loli i kāu hoʻolālā lapaʻau me ʻoe.

Hiki iaʻu ke hele i ka wā lapaʻau?

Hiki iā ʻoe ke hele ma waena o nā lapaʻau, akā he mea nui e hoʻolālā pono i kāu papa hoʻonohonoho injection. E hōʻoia e hoʻi ana ʻoe i ka manawa no kāu manawa e hiki mai ana a loaʻa iā ʻoe ke komo i ka mālama olakino inā e hoʻomohala ʻoe i nā hōʻailona e pili ana i ka wā e hele ana.

E hōʻike i kāu hui mālama ola e pili ana i nā hoʻolālā huakaʻi, ʻoiai inā e hele ana ʻoe i kahi e paʻakikī ai ke kiʻi koke i ka mālama olakino. Hiki iā lākou ke hāʻawi i ke alakaʻi ʻana i ka mea e nānā ai a pehea e mālama ai i nā hopena ʻaoʻao e hiki ke hana i ka wā e hele ana.