He aha ʻo Thiotepa: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau chemotherapy ikaika ʻo Thiotepa i hoʻohana ʻia no ka mālama ʻana i kekahi mau ʻano maʻi maʻi. Hana kēia mea hana alkylating ma ka hoʻōki ʻana i nā cell maʻi mai ka ulu ʻana a me ka mahele ʻana, e kōkua ana i kou kino e hakakā i ka maʻi. ʻOiai he lāʻau ikaika ia me nā hopena ʻaoʻao koʻikoʻi, hiki ke lilo i ʻāpana nui o kāu hoʻolālā lapaʻau maʻi maʻi ke hana ʻole nā koho ʻē aʻe a ʻaʻole kūpono paha.

He aha ʻo Thiotepa?

He lāʻau chemotherapy ʻo Thiotepa e pili ana i kahi hui i kapa ʻia ʻo nā mea hana alkylating. Hāʻawi ʻia ia ma ke ʻano he injection pololei i loko o kou vein a i ʻole ka ʻōpū, ma muli o ke ʻano o ka maʻi maʻi e mālama ʻia nei. Ua hoʻohana ʻia kēia lāʻau lapaʻau no nā makahiki he nui e kōkua i ka poʻe me nā ʻano maʻi maʻi like ʻole, a hana ia ma ka hoʻopilikia ʻana i ka DNA i loko o nā cell maʻi.

Ua manaʻo ʻia ka lāʻau lapaʻau he lāʻau cytotoxic, ʻo ia hoʻi ua hoʻolālā ʻia e ʻona i nā cell - ʻo ia hoʻi nā cell maʻi. E ana pono kāu oncologist i nā pōmaikaʻi e kūʻē i nā pilikia ma mua o ka ʻōlelo ʻana iā thiotepa ma ke ʻano he ʻāpana o kāu hoʻolālā lapaʻau.

No ke aha e hoʻohana ʻia ai ʻo Thiotepa?

Hoʻomaʻamaʻa ʻo Thiotepa i kekahi mau ʻano maʻi maʻi, me ka maʻi maʻi ʻōpū kekahi o kāna mau hoʻohana maʻamau. Hiki i kāu kauka ke ʻōlelo i kēia lāʻau lapaʻau ke loaʻa nā cell maʻi i loko o kou ʻōpū a i ʻole ke hana ʻole nā lāʻau lapaʻau ʻē aʻe.

Ma waho aʻe o ka maʻi maʻi ʻōpū, hiki i ka thiotepa ke kōkua i ka mālama ʻana i ka maʻi maʻi umauma, ka maʻi maʻi ovarian, a me kekahi mau lymphomas. Hoʻohana ʻia ia i kekahi manawa ma mua o nā transplants iwi iwi e kōkua i ka hoʻomākaukau ʻana i kou kino ma ka hōʻemi ʻana i nā cell maʻi. I kekahi mau hihia, hoʻohana nā kauka iā ia e mālama i ka wai e kūkulu ana a puni nā māmā a i ʻole ka ʻōpū i hana ʻia e ka maʻi maʻi.

Hoʻokaʻawale ʻia ka lāʻau lapaʻau no nā kūlana kikoʻī kahi e manaʻoʻiʻo ai kāu hui lapaʻau e hāʻawi ana i ka manawa maikaʻi loa e hakakā i kāu maʻi maʻi. E wehewehe pono kāu oncologist i ke kumu e ʻōlelo nei lākou iā thiotepa no kāu kūlana kūʻokoʻa.

Pehea e hana ai ʻo Thiotepa?

Hana ʻo Thiotepa ma ka hōʻino ʻana i ka DNA i loko o nā pūnaʻi maʻi ʻaʻai, e pale ana iā lākou mai ka hoʻonui ʻana a me ka laha ʻana. E noʻonoʻo iā ia me he mea lā e hoʻopilikia ana i ka hiki o ka pūnaʻi maʻi ʻaʻai ke kope iā ia iho - me ka ʻole o kēia hiki, make nā pūnaʻi maʻi ʻaʻai.

Ua manaʻo ʻia he lāʻau chemotherapy ikaika kēia, ʻo ia hoʻi he mana loa i kāna mau hopena. ʻAʻole e kuhikuhi wale ka lāʻau i nā pūnaʻi maʻi ʻaʻai - hiki nō hoʻi ke hoʻopilikia i nā pūnaʻi olakino e māhele wikiwiki ana, e like me nā mea i loko o kou lauoho, ʻōnaehana digestive, a me ka iwi iwi. ʻO ia ke kumu e ʻike ai ʻoe i nā hopena ʻaoʻao i ka wā o ka mālama ʻana.

ʻO ka maʻamau, he mau pule ka lāʻau e hōʻike ai i kāna hopena piha. E nānā kāu hui lapaʻau i kou holomua ma o nā hoʻokolohua koko a me nā haʻawina kiʻi e ʻike ai i ka maikaʻi o ka hana ʻana o ka lāʻau.

Pehea wau e lawe ai iā Thiotepa?

Hāʻawi mau ʻia ʻo Thiotepa e nā poʻe loea mālama ola i loko o kahi haukapila a i ʻole ke keʻena lapaʻau - ʻaʻole ʻoe e lawe i kēia lāʻau ma ka home. Hāʻawi ʻia ka lāʻau ma o ka laina IV i loko o kou vein a i ʻole pololei i loko o kou ʻōpū ma o ka catheter, ma muli o ke ʻano o ka maʻi ʻaʻai āu e mālama nei.

Ma mua o kāu mālama ʻana, e loaʻa paha iā ʻoe nā lāʻau ʻē aʻe e kōkua ai i ka pale ʻana i ka nausea a me nā hopena maʻi. E nānā pono kāu hui lapaʻau iā ʻoe i ka wā o ka infusion, e lawe ana i 30 mau minuke a i kekahi mau hola ma muli o ka nui a me ke ʻano o ka lawelawe ʻana.

ʻAʻole pono ʻoe e hoʻokē ʻai ma mua o ka mālama ʻana, akā ʻo ka ʻai ʻana i ka meaʻai māmā ma mua e kōkua paha i ka hōʻemi ʻana i ka nausea. E noho maikaʻi i ka wai ma ka inu ʻana i ka wai nui i nā lā e alakaʻi ana i kāu mālama ʻana, ke ʻole e ʻōlelo kāu kauka.

Inā loaʻa iā ʻoe ka hoʻokomo ʻana i ka ʻōpū (lāʻau i waiho pololei ʻia i loko o ka ʻōpū), pono ʻoe e paʻa i ka lāʻau i loko o kou ʻōpū no kahi o ʻelua hola ma mua o ka mimi ʻana. E hāʻawi kāu hui mālama ola iā ʻoe i nā ʻōlelo kikoʻī e pili ana i ke kūlana a me ka manawa.

Pehea ka lōʻihi e lawe ai au iā Thiotepa?

He ʻokoʻa ka lōʻihi o ka mālama ʻana me ka thiotepa ma muli o ke ʻano o kāu maʻi kanesa a me ka maikaʻi o kou pane ʻana i ka lāʻau lapaʻau. Loaʻa ka hapa nui o nā kānaka i ka mālama ʻana i nā pōʻaiapuni, me kēlā me kēia pōʻaiapuni e ukali ʻia e kahi manawa hoʻomaha e hiki ai i kou kino ke ola.

No ka maʻi kanesa o ka ʻōpū, hiki iā ʻoe ke loaʻa i nā lāʻau lapaʻau i kēlā me kēia pule no ʻeono a ʻewalu pule. No nā maʻi kanesa ʻē aʻe, hiki i nā pōʻaiapuni lapaʻau ke hana i kēlā me kēia ʻekolu a ʻehā pule, me ka lōʻihi o ka mālama ʻana i nā mahina he nui. E hana kāu oncologist i kahi papa hana pilikino e pili ana i ke kahua o kāu maʻi kanesa, ke olakino holoʻokoʻa, a me nā pahuhopu lapaʻau.

E loiloi mau kāu hui lapaʻau i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau ma o nā hoʻokolohua koko, nā kiʻi kiʻi, a me nā hoʻokolohua kino. Inā pane maikaʻi ka maʻi kanesa a hiki ke mālama ʻia nā hopena ʻaoʻao, hiki ke hoʻomau ʻia ka mālama ʻana e like me ka mea i hoʻolālā ʻia. Eia naʻe, inā e ulu nā hopena ʻaoʻao koʻikoʻi a i ʻole ʻaʻole pane ka maʻi kanesa, hiki i kāu kauka ke hoʻoponopono i ka hoʻolālā lapaʻau.

He aha nā hopena ʻaoʻao o Thiotepa?

Hiki i ka Thiotepa ke hana i nā hopena ʻaoʻao like ʻole no ka mea e pili ana i nā cell maʻi kanesa a me nā cell olakino e mahele wikiwiki ana. ʻO ka hoʻomaopopo ʻana i ka mea e manaʻo ai hiki ke kōkua iā ʻoe e hoʻomākaukau a ʻike i ka manawa e hoʻopili ai i kāu hui lapaʻau.

ʻO nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike me ka nausea, ka luaʻi, a me ka luhi. Nui nā kānaka e ʻike i nā loli i kā lākou helu koko, hiki ke hoʻonui iā ʻoe i nā maʻi, ka ʻeha, a i ʻole ka luhi. ʻO ka nalowale o ka lauoho kekahi hopena maʻamau, ʻoiai e ulu hou ana kou lauoho ma hope o ka pau ʻana o ka mālama ʻana.

Eia nā hopena ʻaoʻao e ʻike nui ai ʻoe i ka wā o ka mālama ʻana:

• Nausea a me ka luaʻi, ʻoi loa i nā lā mua ma hope o ka mālama ʻana
• Luhi a me ka nāwaliwali e mau ana i nā lā he nui
• Nā helu cell koko haʻahaʻa, e hoʻonui ana iā ʻoe i nā maʻi
• Ka nalowale o ka lauoho, he mea manawa pōkole
• Nā ʻeha waha a i ʻole ka huhū ʻana o ka ʻāʻī
• Nalo o ka ʻai
• Nā hopena ʻili ma ke kahua injection

Hiki ke mālama ʻia kēia mau hopena ʻaoʻao maʻamau me ka mālama kākoʻo a me nā lāʻau lapaʻau hiki i kāu kauka ke kuhikuho. ʻIke ka hapa nui o nā kānaka i nā hopena ʻaoʻao i ʻike nui ʻia i nā lā mua ma hope o ka mālama ʻana a laila e hoʻomaikaʻi mālie.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi e koi ai i ka lāʻau lapaʻau koke. Hiki i kēia mau pilikia laha ʻole akā koʻikoʻi ke hoʻopilikia i kou iwi iwi, ke ake, a i ʻole nā māmā.

E hoʻokaʻaʻike koke i kāu hui mālama ola inā ʻike ʻoe i kekahi o kēia mau hopena ʻaoʻao koʻikoʻi:

• Ka wela ma luna o 100.4°F (38°C) a i ʻole nā hōʻailona o ka maʻi
• Ke kahe ʻana o ke koko a i ʻole ka ʻeha maʻamau
• Ka luaʻi nui a i ʻole ka luaʻi ʻana e pale ai iā ʻoe mai ka mālama ʻana i nā wai
• Paʻakikī ka hanu ʻana a i ʻole ka ʻeha o ka umauma
• Ka maʻi maʻi nui a i ʻole ka ʻeha o ka ʻōpū
• Melemele o ka ʻili a i ʻole nā maka
• ʻO ka luhi nui a i ʻole ka nāwaliwali

ʻOiai ʻaʻole maʻamau kēia mau hopena ʻaoʻao koʻikoʻi, pono lākou i ka loiloi olakino wikiwiki e hōʻoia i kou palekana a hoʻoponopono i ka lāʻau inā pono.

ʻO wai ka mea pono ʻole e lawe iā Thiotepa?

ʻAʻole kūpono ʻo Thiotepa no nā mea a pau, a e nānā pono kāu kauka i kāu mōʻaukala olakino ma mua o ka ʻōlelo ʻana i kēia lāʻau. ʻAʻole kūpono paha nā kānaka me nā ʻōnaehana pale i hoʻopilikia nui ʻia a i ʻole kekahi mau maʻi i loaʻa mua no kēia lāʻau.

ʻAʻole pono ʻoe e loaʻa iā thiotepa inā he maʻi ʻike ʻia ʻoe i ka lāʻau a i ʻole inā ua hoʻopilikia nui ʻia kāu hana iwi iwi. ʻAʻole pono nā wahine hāpai e loaʻa i kēia lāʻau, no ka mea, hiki iā ia ke hōʻeha nui i ka pēpē e ulu ana.

E makaʻala loa kāu kauka i ka ʻōlelo ʻana iā thiotepa inā loaʻa iā ʻoe kekahi o kēia mau maʻi:

• Maʻi kīkī a i ʻole ke ake nui
• Nā maʻi hana a i ʻole ka ʻōnaehana pale i nāwaliwali loa
• ʻO ka lāʻau lapaʻau radiation mua i nā wahi nui o kou kino
• Mōʻaukala o nā hopena maʻi maʻi nui i ka chemotherapy
• Hāpai a i ʻole ka hānai ʻana i ka waiū
• Nā helu koko haʻahaʻa loa

ʻOiai inā loaʻa iā ʻoe kekahi o kēia mau maʻi, ʻaʻole ia he manaʻo e hiki ʻole iā ʻoe ke loaʻa ka thiotepa. E ana kāu kauka oncologist i nā pōmaikaʻi e hiki mai ana i nā pilikia a e hoʻoponopono paha i ka mahele a i ʻole e hāʻawi i ka nānā ʻana a me ke kākoʻo.

Nā inoa inoa o Thiotepa

Loaʻa ka Thiotepa ma lalo o nā inoa inoa like ʻole, ʻoiai ʻo ka mana generic ka mea i hoʻohana nui ʻia. Ma ʻAmelika Hui Pū ʻIa, e hālāwai paha ʻoe me ia ma ke ʻano he Tepadina, ʻo ia ka inoa inoa o ka lāʻau lapaʻau like.

Inā loaʻa iā ʻoe ka inoa inoa a i ʻole ka mana generic, ua like ka mea hana a me ka pono. E hōʻoia kāu hale kūʻai lāʻau lapaʻau a me ka hui lapaʻau e loaʻa iā ʻoe ka hoʻomākaukau kūpono no kāu hoʻolālā lapaʻau.

Hele mai ka lāʻau lapaʻau ma ke ʻano he pauka i hui pū ʻia me ka wai sterile ma mua o kāu lapaʻau. E hōʻoia kēia i ka paʻa a me ka pono o ka lāʻau i ka wā e lawelawe ʻia ai.

Nā koho ʻē aʻe o Thiotepa

Nui nā lāʻau lapaʻau chemotherapy ʻē aʻe e hiki ke mālama i nā ʻano maʻi maʻi like, ʻoiai ʻo ke koho maikaʻi loa e pili ana i kāu kūlana. E noʻonoʻo kāu kauka oncologist i nā mea e like me ke ʻano o kāu maʻi maʻi, ke kahua, nā lāʻau lapaʻau mua, a me ke olakino holoʻokoʻa i ke koho ʻana i nā koho ʻē aʻe.

No ka maʻi maʻi ʻōpū, hiki i nā koho ʻē aʻe ke komo i ka mitomycin C, doxorubicin, a i ʻole BCG immunotherapy. Hana ʻokoʻa kēlā me kēia o kēia mau lāʻau lapaʻau a loaʻa iā lākou nā pōmaikaʻi a me nā hopena ʻaoʻao. ʻOi aku ka maikaʻi o kekahi poʻe me kekahi lāʻau lapaʻau ma luna o kekahi e pili ana i kā lākou pane a me ka ʻae ʻana.

Ke loaʻa nei nā lāʻau lapaʻau i manaʻo ʻia a me nā immunotherapies no kekahi mau ʻano maʻi maʻi i mālama ʻia me ka thiotepa. Hiki i kēia mau lāʻau lapaʻau hou ke loaʻa nā ʻano hopena ʻaoʻao like ʻole a he mau koho paha e kūkākūkā me kāu hui lapaʻau.

ʻOi aku ka maikaʻi o Thiotepa ma mua o Mitomycin C?

He mea maikaʻi nā lāʻau chemotherapy ʻo Thiotepa a me mitomycin C i ka mālama ʻana i ka maʻi ʻaʻai o ka ʻōpū, akā ʻaʻole i ʻoi aku kekahi ma mua o kekahi. Aia ke koho ma waena o lākou i nā ʻano o kāu maʻi ʻaʻai, nā lāʻau lapaʻau i hala, a me ka maikaʻi o kou ʻae ʻana i kēlā me kēia lāʻau.

He liʻiliʻi nā hopena maʻi maʻi koʻikoʻi o Thiotepa i hoʻohālikelike ʻia me mitomycin C, e lilo ana ia i koho maikaʻi no nā poʻe me nā ʻōnaehana pale maʻi maʻi. Eia naʻe, ʻoi aku ka maikaʻi o mitomycin C no kekahi mau ʻano o nā pūnaewele maʻi ʻaʻai o ka ʻōpū.

E noʻonoʻo kāu kauka oncologist i kāu kiʻi olakino piha i ke koho ʻana ma waena o kēia mau koho. Hiki i kekahi poʻe ke hoʻāʻo i hoʻokahi lāʻau lapaʻau mua a hoʻololi i kekahi inā ʻaʻole maikaʻi ka lāʻau lapaʻau mua a i ʻole e hana i nā hopena ʻaoʻao hiki ʻole ke ʻae ʻia.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Thiotepa

He Palekana ʻo Thiotepa no ka poʻe me ka maʻi kīkī?

Hiki ke hoʻohana ʻia ʻo Thiotepa i ka poʻe me ka maʻi kīkī maʻalahi a me ka maʻi, akā pono ia i ka nānā pono ʻana a me ka hoʻoponopono ʻana i ka mahele. E nānā kāu kauka i ka hana o kou kīkī ma o nā hoʻokolohua koko ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau a me ka manawa maʻamau i kāu lāʻau lapaʻau.

Inā loaʻa iā ʻoe ka maʻi kīkī koʻikoʻi, hiki i kāu kauka oncologist ke ʻōlelo i kahi lāʻau lapaʻau ʻē aʻe a i ʻole e hōʻemi nui i ka mahele thiotepa. ʻO ka pahuhopu ka mālama ʻana i ka pono o ka hakakā ʻana i ka maʻi ʻaʻai i ka wā e pale ana i ka hana o kou kīkī i koe.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Thiotepa?

No ka mea, hāʻawi ʻia ʻo thiotepa e nā poʻe loea olakino i nā wahi lapaʻau, he mea maʻamau loa nā overdoses ulia. Inā hopohopo ʻoe e loaʻa ana ka nui o ka lāʻau lapaʻau, e kamaʻilio koke me kāu kahu hānai a i ʻole kauka i ka wā o kāu kau lapaʻau.

He nui nā loiloi palekana i loaʻa i nā hui mālama ola e pale ai i nā hewa dosing, me ka nānā pālua ʻana i nā helu a me ka hōʻoia ʻana i kou ʻike ma mua o kēlā me kēia lāʻau lapaʻau. Inā loaʻa kahi overdose, e hāʻawi kāu hui lapaʻau i ka mālama kākoʻo koke a me ka nānā ʻana.

He aha kaʻu e hana ai inā ua hala wau i kahi mahele o Thiotepa?

Inā ua hala ʻoe i kahi manawa i hoʻonohonoho ʻia no ka thiotepa, e launa me kāu hui oncology i ka wā hiki wawe e hoʻonohonoho hou. Hiki i ka hala ʻana i nā mahele ke hōʻemi i ka pono o kāu lapaʻau, no laila he mea nui e mālama i kāu papa i kuhikuhi ʻia i ka wā hiki.

E kōkua kāu hui lapaʻau iā ʻoe e hoʻonohonoho hou a hiki ke hoʻoponopono i kāu hoʻolālā lapaʻau inā pono. Mai ho'āʻo e