He aha ka Trastuzumab-DTTB: Nā hoʻohana, ka nui, nā hopena ʻaoʻao a me nā mea hou aku

ʻO Trastuzumab-DTTB he lāʻau lapaʻau maʻi i manaʻo ʻia e kōkua i ka mālama ʻana i kekahi mau ʻano maʻi maʻi umauma a me ka maʻi ʻōpū. Hana ia ma ka pale ʻana i nā protein kikoʻī e hoʻoulu ai i ka ulu ʻana o ka maʻi maʻi, e hāʻawi ana i kou ʻōnaehana pale i kahi manawa maikaʻi e hakakā i ka maʻi.

No kēia lāʻau lapaʻau i kahi hui i kapa ʻia ʻo monoclonal antibodies, ʻo ia nā protein i hana ʻia i ka lab i hoʻolālā ʻia e kuhikuhi i nā cell maʻi maʻi. E noʻonoʻo iā ia he missile alakaʻi e ʻimi a hoʻouka wale i nā cell maʻi maʻi me ka waiho ʻana i ka hapa nui o nā cell olakino.

He aha ka Trastuzumab-DTTB?

ʻO Trastuzumab-DTTB kahi mana biosimilar o ka lāʻau lapaʻau trastuzumab kumu. ʻO ka biosimilar ke ʻano like ia me ka lāʻau kumu akā hana ʻia e kahi mea hana ʻē aʻe, e hāʻawi ana iā ʻoe i nā pōmaikaʻi like ma nā kumukūʻai haʻahaʻa.

Hoʻopili pono ka lāʻau lapaʻau i nā cell maʻi maʻi i loaʻa ka nui o ka protein i kapa ʻia ʻo HER2. Ma kahi o 15-20% o nā maʻi maʻi umauma a me kekahi mau maʻi maʻi ʻōpū i kēia protein HER2 i nā mea kiʻekiʻe, e wikiwiki ai ka maʻi maʻi a laha nui.

E hoʻāʻo kāu kauka i kāu ʻiʻo maʻi maʻi e ʻike inā he kiʻekiʻe ka HER2 ma mua o ka ʻōlelo ʻana i kēia lapaʻau. ʻO nā maʻi maʻi maʻi i hoʻāʻo maikaʻi no HER2 e pane i kēia lāʻau.

No ke aha i hoʻohana ʻia ai ʻo Trastuzumab-DTTB?

Hoʻomaʻamaʻa ʻo Trastuzumab-DTTB i ka maʻi maʻi umauma HER2-positive a me ka maʻi ʻōpū HER2-positive. Hiki ke hoʻohana ʻia inā ua laha kāu maʻi maʻi i nā ʻāpana ʻē aʻe o kou kino a i ʻole e paʻa ana i hoʻokahi wahi.

No ka maʻi maʻi umauma, hoʻohana pinepine nā kauka i kēia lāʻau lapaʻau i kekahi mau kūlana. Hiki iā ʻoe ke loaʻa ma hope o ke ʻoki ʻana e pale ai i ka maʻi maʻi mai ka hoʻi ʻana mai, a i ʻole me ka chemotherapy inā ua laha kāu maʻi maʻi i nā lymph nodes a i ʻole nā wahi ʻē aʻe.

I nā hihia maʻi 'aʻai ʻōpū, hana maʻamau kēia lāʻau lapaʻau me ka chemotherapy e kōkua i ka hōʻemi ʻana i nā ʻōpū a me ka hoʻolohi ʻana i ka holomua o ka maʻi 'aʻai. E hoʻoholo kāu hui mālama ola i ka hui pū ʻana o nā lāʻau lapaʻau maikaʻi loa e pili ana i kāu kūlana.

Pehea e Hana ai ʻo Trastuzumab-DTTB?

Hana ʻo Trastuzumab-DTTB ma ka hoʻopili ʻana i ka protein HER2 ma nā sela maʻi 'aʻai a me ka pale ʻana i nā hōʻailona e haʻi ana i ka maʻi 'aʻai e ulu. Manaʻo ʻia he lāʻau lapaʻau i manaʻo ʻia he ikaika e hakakā ana i nā maʻi 'aʻai HER2-positive.

Ke hoʻopili ʻia i ka protein HER2, hoʻouna ka lāʻau lapaʻau i nā hōʻailona i kāu ʻōnaehana pale e hoʻouka i kēlā mau sela maʻi 'aʻai. Pale pū nō hoʻi ia i nā sela maʻi 'aʻai mai ka loaʻa ʻana o nā hōʻailona ulu e pono ai lākou e hoʻonui a laha.

ʻAʻole hana ka lāʻau lapaʻau e like me ka chemotherapy kuʻuna e pili ana i nā sela e māhele wikiwiki ana. Akā, e kālele ana ia i nā sela maʻi 'aʻai me ka protein HER2, ʻo ia hoʻi, ʻoi aku ka liʻiliʻi o nā hopena ʻaoʻao ma mua o nā lāʻau lapaʻau maʻi 'aʻai ākea.

Pehea e Lawe ai au iā Trastuzumab-DTTB?

Hāʻawi ʻia ʻo Trastuzumab-DTTB ma o ka IV (intravenous) infusion ma kahi haukapila a i ʻole ke kikowaena lapaʻau maʻi 'aʻai. ʻAʻole hiki iā ʻoe ke lawe i kēia lāʻau lapaʻau ma ka home, no ka mea, pono e nānā pono ʻia e nā poʻe loea mālama ola.

E lawe ana kāu infusion mua ma kahi o 90 mau minuke, ʻoiai e lawe maʻamau nā mea ma hope ma kahi o 30-60 mau minuke. Hoʻohui ʻia ka lāʻau lapaʻau me ka hopena saline a hoʻokuʻu mālie ʻia i loko o kou kahe koko ma o ka nila i kou lima a i ʻole ma o ke awa inā loaʻa iā ʻoe.

ʻAʻole pono ʻoe e ʻai i nā meaʻai kikoʻī ma mua o ka lapaʻau, akā ʻo ka noho ʻana i ka wai maikaʻi ma ka inu ʻana i ka wai nui hiki ke kōkua i kou kino e mālama maikaʻi i ka lāʻau lapaʻau. Manaʻo kekahi poʻe he mea kōkua ke ʻai i ka ʻai māmā ma mua e pale ai i ka nausea.

E nānā pono kāu hui mālama ola iā ʻoe i ka wā o kēlā me kēia infusion a no hoʻokahi hola ma hope. E nānā lākou i kāu mau hōʻailona koʻikoʻi a nānā i nā hopena koke i ka lāʻau lapaʻau.

Pehea ka lōʻihi e lawe ai au i ka Trastuzumab-DTTB?

Aia ka lōʻihi o ka mālama ʻana me ka trastuzumab-DTTB i kāu ʻano maʻi maʻi a me nā pahuhopu lapaʻau. Loaʻa ka mālama ʻana i ka hapa nui o nā kānaka no hoʻokahi makahiki, ʻo ia hoʻi ka loaʻa ʻana o nā infusions i kēlā me kēia ʻekolu pule.

Inā loaʻa iā ʻoe kēia lāʻau lapaʻau e pale ai i ka maʻi maʻi umauma mai ka hoʻi ʻana mai ma hope o ke ʻoki ʻana, e loaʻa paha iā ʻoe no 12 mahina. Ua hōʻike ʻia kēia manawa e hāʻawi i ke kaulike maikaʻi loa o nā pōmaikaʻi me ka hōʻemi ʻana i nā hopena ʻaoʻao lōʻihi.

No ka maʻi maʻi holomua a i ʻole metastatic, hiki iā ʻoe ke hoʻomau i ka mālama ʻana i ka wā e kōkua ana i ka mālama ʻana i kāu maʻi maʻi a ke ʻae maikaʻi nei ʻoe. E nānā mau kāu kauka i ka pane ʻana o kāu maʻi maʻi a hoʻoponopono i kāu hoʻolālā lapaʻau.

Mai hooki i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole e kamaʻilio mua me kāu hui mālama ola. ʻOiai inā ʻoe e ʻoi aku ka maikaʻi, ʻo ka hoʻopau ʻana i ka papa lapaʻau piha e hāʻawi iā ʻoe i ka manawa maikaʻi loa e pale ai i ka maʻi maʻi mai ka hoʻi ʻana mai.

He aha nā hopena ʻaoʻao o Trastuzumab-DTTB?

ʻO ka hapa nui o nā kānaka e ʻike i kekahi mau hopena ʻaoʻao me ka trastuzumab-DTTB, akā hiki ke mālama ʻia me ke kākoʻo kūpono a me ka nānā ʻana. ʻO nā hopena ʻaoʻao maʻamau he maʻalahi a i ka waena a hoʻomaikaʻi i ka manawa.

Eia nā hopena ʻaoʻao āu e ʻike ai, e hoʻomaka ana me nā mea maʻamau:

• Luhi a me ka luhi ma mua o ka maʻamau
• Nā poʻo poʻo e hiki ke hele mai a hele
• Nausea a me ka luaʻi i kekahi manawa
• Diarrhea a i ʻole nā ​​hoʻololi i nā neʻe ʻana o ka ʻōpū
• ʻO nā ʻehaʻeha ʻiʻo a me nā hui
• ʻO ke kuni a me nā anu, ʻoi aku ma hope o nā infusions mua
• ʻO ka ʻili ʻili a i ʻole ka huhū ma ke kahua infusion

ʻO kēia mau hopena ʻaoʻao maʻamau e lilo pinepine i mea hoʻonāukiuki i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau. Hiki i kāu hui mālama ola ke hāʻawi i nā lāʻau lapaʻau a me nā hoʻolālā e kōkua i ka mālama ʻana i kēia mau hōʻailona.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi e pono ai ka mālama olakino koke. ʻOiai ʻaʻole maʻamau kēia mau mea, he mea nui e ʻike i ka mea e nānā ai:

• Nā pilikia o ka naʻau, me ka pōkole o ka hanu a i ʻole ka ʻeha o ka umauma
• Nā hopena maʻi maʻi koʻikoʻi i ka wā a i ʻole ma hope koke o ka hoʻokomo ʻana
• Nā hōʻailona o ka maʻi, e like me ke kuni mau a i ʻole ka nāwaliwali ʻole
• Nā pilikia o ka māmā, me ka ʻū mau a i ʻole ka pilikia o ka hanu
• Ka pehu nui ʻana i kou mau wāwae, nā kuʻekuʻe wāwae, a i ʻole ka maka

E nānā mau kāu kauka i ka hana o kou puʻuwai i ka wā o ka mālama ʻana, no ka mea, hiki i kēia lāʻau lapaʻau ke hoʻopilikia i ka maikaʻi o ka puʻuwai e pauma i ke koko. ʻAʻole nui ka poʻe e loaʻa i nā pilikia o ka naʻau, akā ʻo ka ʻike mua ʻana e hiki ai ke hoʻoponopono wikiwiki ʻia inā pono.

ʻO wai ka mea pono ʻole e lawe iā Trastuzumab-DTTB?

ʻAʻole kūpono ʻo Trastuzumab-DTTB no nā mea a pau, a e nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ka ʻōlelo ʻana i kēia lapaʻau. ʻAʻole hiki i nā poʻe me kekahi mau maʻi puʻuwai ke loaʻa i kēia lāʻau lapaʻau.

ʻAʻole pono ʻoe e loaʻa iā trastuzumab-DTTB inā loaʻa iā ʻoe kahi hopena maʻi maʻi koʻikoʻi i ʻike ʻia i ka trastuzumab a i ʻole kekahi o kāna mau mea. E makaʻala nō hoʻi kāu kauka inā he moʻolelo kou o nā pilikia o ka naʻau a i ʻole ka hana puʻuwai i hōʻemi nui ʻia.

Inā hāpai ʻoe a i ʻole e hoʻolālā ana e hāpai, hiki i kēia lāʻau lapaʻau ke hōʻeha i kāu pēpē e ulu ana. E kūkākūkā kāu hui mālama ola i nā koho hoʻomalu hānau kūpono me ʻoe i ka wā o ka mālama ʻana a no kekahi mau mahina ma hope o kāu mahele hope loa.

Pono paha ka poʻe me nā maʻi koʻikoʻi e kali a hiki i ka wā e mālama ʻia ai ka maʻi ma mua o ka hoʻomaka ʻana i ka mālama ʻana. Pono e lawa ka ikaika o kāu ʻōnaehana pale e hakakā ai i ka maʻi a me ka loaʻa ʻana o ka lapaʻau maʻi.

Nā inoa inoa Trastuzumab-DTTB

Loaʻa ʻo Trastuzumab-DTTB ma lalo o ka inoa inoa ʻo Ogivri. ʻO kēia ka mana biosimilar e hāʻawi ana i ka pono like me ka lāʻau trastuzumab kumu akā pinepine ma ke kumu kūʻai haʻahaʻa.

Hele ka lāʻau trastuzumab kumu ma ka inoa inoa ʻo Herceptin. Hana like nā lāʻau ʻelua a loaʻa nā hopena ʻaoʻao like, no laila hiki i kāu kauka ke hoʻohana i kekahi o lākou ma muli o ka loaʻa a me kāu ʻinikua.

Hiki i kekahi mau kikowaena lapaʻau ke kuhikuhi i kēia lāʻau lapaʻau ma ke ʻano he

E koho kāu kauka ma waena o kēia mau koho ma muli o nā mea e like me kāu ʻinikua, nā makemake o ke kikowaena lapaʻau, a me ka loaʻa. Mai kahi manaʻo lapaʻau, ua manaʻo ʻia nā lāʻau lapaʻau ʻelua he mea maikaʻi like no ka mālama ʻana i nā maʻi maʻi HER2-positive.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Trastuzumab-DTTB

He palekana anei ʻo Trastuzumab-DTTB no ka poʻe me ka maʻi puʻuwai?

Pono ʻo Trastuzumab-DTTB i ka noʻonoʻo pono inā he pilikia kou puʻuwai. E loiloi kāu kauka i ka hana o kou puʻuwai ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau a nānā mau iā ia i ka wā o kāu mālama ʻana.

Hiki i ka nui o ka poʻe me nā maʻi puʻuwai maʻalahi ke loaʻa palekana i kēia lāʻau lapaʻau me ka nānā pono ʻana. E hana pū kāu hui cardio-oncology e hōʻoia i ka olakino o kou puʻuwai i ka wā e loaʻa ai iā ʻoe ka lāʻau lapaʻau maʻi maikaʻi.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Trastuzumab-DTTB?

No ka mea, hāʻawi ʻia ʻo trastuzumab-DTTB e nā poʻe loea mālama ola i kahi hoʻonohonoho lapaʻau, he mea maʻamau loa ka nui o ka lāʻau lapaʻau. Hoʻohālikelike ʻia ka lāʻau lapaʻau a hāʻawi ʻia ma muli o ke kaumaha o kou kino a me ke kūlana olakino.

Inā hopohopo ʻoe e pili ana i kāu mahele a i ʻole e ʻike i nā hōʻailona maʻamau ma hope o ka lāʻau lapaʻau, e hoʻokaʻaʻike koke i kāu hui mālama ola. Hiki iā lākou ke loiloi i kou kūlana a hāʻawi i ka mālama kūpono inā pono.

He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Trastuzumab-DTTB?

Inā hala ʻoe i kahi manawa hoʻokomo i hoʻonohonoho ʻia, e hoʻokaʻaʻike i kāu hui mālama ola i ka hiki wawe e hoʻonohonoho hou. E hana pū lākou me ʻoe e hoʻi i ke ala me kāu papa hana lapaʻau.

ʻO ka hala ʻana i hoʻokahi mahele i kekahi manawa ʻaʻole ia e hoʻopilikia nui i ka maikaʻi o kāu lāʻau lapaʻau, akā he mea nui e mālama i kahi papa hana kūlike e like me ka hiki. Hiki i kāu hui lapaʻau ke hoʻoponopono iki i kāu manawa lapaʻau e hoʻokō i nā manawa i hala.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Trastuzumab-DTTB?

Pono ʻoe e hooki i ka trastuzumab-DTTB ma hope wale nō o ke kūkākūkā ʻana me kāu kauka oncologist. Hoʻopau ka hapa nui o nā kānaka i kā lākou papa lapaʻau i kuhikuhi ʻia, ʻo ia hoʻi ma kahi o hoʻokahi makahiki no ka maʻi ʻaʻai umauma i ke kahua mua.

E noʻonoʻo kāu kauka i nā mea e like me ka maikaʻi o ka hana ʻana o ka lapaʻau, nā hopena ʻaoʻao āu e ʻike nei, a me kou olakino holoʻokoʻa i ka wā e hoʻoholo ai e pili ana i ka hooki ʻana i ka lapaʻau. Mai hooki i kēia lāʻau lapaʻau ma kāu iho, ʻoiai inā ʻoe e maikaʻi ana.

Hiki iaʻu ke hāpai i ka wā e lawe ana i ka Trastuzumab-DTTB?

ʻAʻole pono ʻoe e hāpai i ka wā e loaʻa ana iā trastuzumab-DTTB, no ka mea, hiki iā ia ke hōʻeha i kāu pēpē e ulu ana. E hoʻohana i ka mana hānau kūpono i ka wā lapaʻau a no ka liʻiliʻi o ʻehiku mahina ma hope o kāu mahele hope loa.

Inā ʻoe e hoʻolālā ana e loaʻa nā keiki i ka wā e hiki mai ana, e kūkākūkā i nā koho mālama momona me kāu hui mālama ola ma mua o ka hoʻomaka ʻana i ka lapaʻau. Hiki iā lākou ke kōkua iā ʻoe e hoʻomaopopo i kāu mau koho a hoʻohui iā ʻoe me nā loea kūpono inā pono.