He aha ka Ublituximab-xiiy: Nā hoʻohana, ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau lapaʻau i kauoha ʻia ka Ublituximab-xiiy e mālama i kekahi mau ʻano maʻi maʻi koko, ʻo ia hoʻi ka leukemia lymphocytic maʻi (CLL) a me ka lymphoma lymphocytic liʻiliʻi (SLL). Hana kēia lāʻau lapaʻau ma ka ʻimi ʻana i nā protein kikoʻī ma nā pūnaewele maʻi e kōkua i kāu ʻōnaehana pale e hakakā i ka maʻi me ka maikaʻi.

Loaʻa iā ʻoe kēia lapaʻau ma o ka laina intravenous (IV) pololei i loko o kou kahe koko, maʻamau i kahi keʻena mālama ola kahi e hiki ai i nā poʻe loea lapaʻau ke nānā pono iā ʻoe. No ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies ka lāʻau lapaʻau, i hoʻolālā ʻia e ʻimi a hoʻopili i nā pahuhopu kikoʻī ma nā pūnaewele maʻi.

He aha ka Ublituximab-xiiy?

ʻO ka Ublituximab-xiiy he lāʻau monoclonal antibody e kōkua ana i ka mālama ʻana i nā maʻi maʻi koko ma ka hana ʻana me kāu ʻōnaehana pale. E noʻonoʻo iā ia he missile alakaʻi e ʻimi pono ana i nā pūnaewele maʻi me ka waiho ʻana i ka hapa nui o kāu mau pūnaewele olakino.

ʻO kēia lāʻau lapaʻau ka mea a nā kauka e kapa ai he

Hiki i kāu kauka ke kuhikuhi i kēia lāʻau lapaʻau ke ʻike mua ʻia ʻoe me CLL a i ʻole SLL, a i ʻole inā ua hoʻi mai kāu maʻi maʻi ma hope o nā lāʻau lapaʻau mua. Hoʻohana pinepine ʻia ia me nā lāʻau lapaʻau maʻi maʻi ʻē aʻe e hana i kahi ala lapaʻau piha.

He mea kōkua nui ka lāʻau lapaʻau no ka poʻe nona nā cell maʻi maʻi i nā ʻano kikoʻī e lilo ai lākou i mea maikaʻi no kēia ʻano lapaʻau. E hana kāu hui mālama ola i nā hoʻokolohua e hoʻoholo ai inā e pane maikaʻi ana kāu maʻi maʻi i ka ublituximab-xiiy.

Pehea e Hana ai ʻo Ublituximab-xiiy?

Hana ʻo Ublituximab-xiiy ma ka ʻimi ʻana i kahi protein i kapa ʻia ʻo CD20 e noho ana ma ka ʻili o kekahi mau cell maʻi maʻi. Hana kēia protein e like me ka lepili inoa e kōkua ai i ka lāʻau lapaʻau e ʻike i nā cell e hoʻouka ai.

Ke hoʻopili ka lāʻau lapaʻau i ka protein CD20, hoʻomaka ia i nā kaʻina hana he nui e alakaʻi ai i ka make ʻana o nā cell maʻi maʻi. Hoʻomaopopo kāu ʻōnaehana pale i ka lāʻau lapaʻau i hoʻopili ʻia ma ke ʻano he hōʻailona e luku i kēlā mau cell, ʻoiai hiki i ka lāʻau lapaʻau ke hoʻoulu i nā cell maʻi maʻi e luku iā lākou iho.

Ua manaʻo ʻia he lāʻau lapaʻau maʻi maʻi ikaika e hiki ke maikaʻi loa ke hoʻohana pono ʻia. Eia naʻe, no ka mea e ʻimi ana i kāu ʻōnaehana pale, pono ʻoe e nānā pono i kāu lapaʻau e nānā i nā pilikia.

Pehea wau e lawe ai iā Ublituximab-xiiy?

E loaʻa iā ʻoe ka ublituximab-xiiy ma o ka hoʻokomo ʻana i ka IV i loko o kahi hale mālama ola, ʻaʻole ma ke ʻano he pila āu e lawe ai ma ka home. Hāʻawi ʻia ka lāʻau lapaʻau me ka lohi i nā hola he nui, a e nānā pono nā poʻe loea mālama ola iā ʻoe i kēlā me kēia kau lapaʻau.

Ma mua o kēlā me kēia hoʻokomo ʻana, e loaʻa paha iā ʻoe nā lāʻau lapaʻau ma mua e kōkua ai i ka pale ʻana i nā hopena maʻi a hoʻemi i nā hopena ʻaoʻao. Hiki i kēia mau mea ke komo i nā antihistamines, acetaminophen, a i ʻole nā ​​steroids i hāʻawi ʻia ma kahi o 30 mau minuke ma mua o ka hoʻomaka ʻana o kāu lapaʻau ublituximab-xiiy.

ʻAʻole pono ʻoe e pale i ka ʻai ma mua o ka mālama ʻana, akā he mea naʻauao e ʻai i ka meaʻai māmā ma mua no ka mea hiki i ke kaʻina hana hoʻokomo ke lawe i nā hola he nui. ʻO ka noho ʻana i ka wai maikaʻi ma ka inu ʻana i ka wai nui i nā lā e alakaʻi ana i ka mālama ʻana hiki ke kōkua i kou kino e mālama maikaʻi i ka lāʻau.

E hāʻawi kāu hui mālama ola i nā ʻōlelo kikoʻī e pili ana i nā lāʻau lapaʻau āu e pale ai ma mua o ka mālama ʻana a me nā mea e lawe mai ai e ʻoluʻolu ai i kāu kau hoʻokomo.

Pehea ka lōʻihi e pono ai au e lawe iā Ublituximab-xiiy?

ʻO ka lōʻihi o ka mālama ʻana iā ublituximab-xiiy e ʻokoʻa ma muli o kou kūlana kikoʻī a me ka maikaʻi o kou pane ʻana i ka lāʻau. Loaʻa ka mālama ʻana i ka hapa nui o nā kānaka no nā mahina he nui, me nā hoʻokomo ʻana i hāʻawi ʻia i hoʻokahi manawa i kēlā me kēia mau pule.

E hana kāu kauka i kahi papa hana lapaʻau i kūpono i kāu mau pono, e pili ana paha i kahi pae ikaika mua a ukali ʻia e nā mālama mālama. Hiki i kekahi poʻe ke loaʻa ka lāʻau no ʻeono mahina, a pono paha kekahi poʻe no hoʻokahi makahiki a ʻoi aku paha.

I loko o kāu mālama ʻana, e nānā mau kāu hui mālama ola i kou holomua ma o nā hoʻokolohua koko, nā scans, a me nā hoʻokolohua kino. Ma muli o kēia mau hopena, hiki iā lākou ke hoʻololi i kāu papa hana lapaʻau a i ʻole e hoʻoholo i ka manawa kūpono e hoʻōki i ka lāʻau.

Mai hoʻōki i ka lawe ʻana iā ublituximab-xiiy iā ʻoe iho, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi. ʻAʻole paha i pau loa kāu maʻi maʻi, a ʻo ka hoʻōki ʻana i ka mālama ʻana i ka wā mua hiki ke ʻae iā ia e hoʻi a i ʻole e ʻino.

He aha nā hopena ʻaoʻao o Ublituximab-xiiy?

E like me nā lāʻau lapaʻau maʻi maʻi a pau, hiki i ka ublituximab-xiiy ke kumu i nā hopena ʻaoʻao, ʻoiai ʻaʻole i loaʻa nā mea a pau iā lākou. Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao, a he ʻike ko kāu hui mālama ola i ke kōkua ʻana i nā maʻi ma o nā pilikia e kū mai ana.

Eia kekahi mau hopena ʻaoʻao maʻamau āu e ʻike ai i ka wā o ka mālama ʻana:

• Luhi a me ka piʻi ʻana o ka luhi ma mua o ka maʻamau
• Luaʻi a i ʻole ka ʻōpū
• ʻEha poʻo
• ʻEha ʻiʻo a i ʻole nā hono
• Liva a i ʻole ke anu
• Pāpaʻa ʻili a i ʻole ka ʻū
• Pāpaʻa
• Hoʻemi ʻia ka ʻai

Hoʻomaikaʻi pinepine kēia mau hōʻailona i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau, a hiki i kāu hui mālama ola ke hāʻawi i nā lāʻau lapaʻau a i ʻole nā hoʻolālā e kōkua i ka mālama pono ʻana iā lākou.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi e koi ai i ka lāʻau lapaʻau koke. ʻOiai ʻaʻole maʻamau kēia mau mea, he mea nui e ʻike i nā hōʻailona ʻōlelo aʻo ʻaʻole pono e mālama ʻole ʻia:

• Nā hōʻailona o ka maʻi koʻikoʻi e like me ke kuni mau, ke anu, a i ʻole ka nāwaliwali ʻole
• Nā hopena maʻi maʻi koʻikoʻi i ka wā a i ʻole ma hope o ka hoʻokomo ʻana
• Ke kahe ʻana o ke koko a i ʻole ka ʻeha ʻana
• ʻEha ʻōpū nui
• Ka pilikia o ka hanu ʻana a i ʻole ka ʻeha o ka umauma
• Nā loli nui i ka mimi

E nānā pono kāu hui lapaʻau iā ʻoe no kēia mau hopena koʻikoʻi a hāʻawi i ka mālama koke inā pono. ʻO ka hapa nui o nā kānaka e ʻae maikaʻi iā ublituximab-xiiy, ʻoiai me ka mālama olakino kūpono.

ʻO wai ka mea ʻaʻole pono e lawe iā Ublituximab-xiiy?

ʻAʻole kūpono ʻo Ublituximab-xiiy no nā mea a pau, a e loiloi pono kāu kauka inā ʻo ia ka lāʻau lapaʻau kūpono nāu. Pono paha nā kānaka me kekahi mau maʻi olakino a i ʻole nā kūlana i nā lāʻau lapaʻau ʻē aʻe.

E ʻōlelo paha kāu kauka i kēia lāʻau lapaʻau inā loaʻa iā ʻoe nā maʻi koʻikoʻi e hakakā nei kou kino. No ka mea e pili ana ʻo ublituximab-xiiy i kāu ʻōnaehana pale, hiki iā ia ke hoʻonui i nā maʻi e kū nei a i ʻole e paʻakikī ke mālama.

Pono paha nā kānaka me kekahi mau maʻi puʻuwai i nā hana kūikawā a i ʻole nā lāʻau lapaʻau ʻē aʻe, no ka mea, hiki i ka lāʻau lapaʻau ke pili i ka hana o ka puʻuwai i kekahi manawa. E nānā kāu kauka i kou olakino puʻuwai ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau.

Inā hāpai ʻoe a i ʻole e hoʻāʻo nei e hāpai, ʻaʻole i ʻōlelo ʻia kēia lāʻau lapaʻau no ka mea hiki ke hōʻeha i ka pēpē e ulu ana. Pono nā wāhine e hiki ke hāpai e hoʻohana i ka mana hānau kūpono i ka wā o ka mālama ʻana a no kekahi mau mahina ma hope.

Pono paha nā kānaka me ka maʻi ate koʻikoʻi a i ʻole kekahi mau maʻi autoimmune i nā ala lapaʻau like ʻole, no ka mea, hiki i ka ublituximab-xiiy ke hoʻopilikia i kēia mau maʻi.

Nā inoa inoa inoa Ublituximab-xiiy

Loaʻa ka Ublituximab-xiiy ma lalo o ka inoa inoa Briumvi. ʻO kēia ka inoa kalepa āu e ʻike ai ma nā lepili lāʻau a me nā ʻōnaehana lāʻau lapaʻau.

Mai ka wā he lāʻau biosimilar kēia, hiki nō iā ʻoe ke hālāwai me nā kuhikuhi i ka lāʻau kumu i hoʻokumu ʻia ai. E hōʻoia kāu hui mālama ola e loaʻa iā ʻoe ka formulation pololei me ka nānā ʻole i ka inoa inoa kikoʻī i hoʻohana ʻia.

E hōʻoia mau me kāu mea mālama ola a i ʻole ka mea kūʻai lāʻau lapaʻau inā he nīnau kāu e pili ana i ka inoa inoa a i ʻole ka formulation āu e loaʻa nei, no ka mea, kōkua kēia i ka hōʻoia ʻana e loaʻa iā ʻoe ka lāʻau lapaʻau kūpono.

Nā koho ʻē aʻe o Ublituximab-xiiy

Nui nā lāʻau lapaʻau ʻē aʻe e hiki ke mālama i ka CLL a me SLL, akā ʻo ke koho maikaʻi loa e hilinaʻi ʻia i kāu kūlana kikoʻī a me ka mōʻaukala olakino. E noʻonoʻo kāu oncologist i nā mea e like me kou makahiki, ke olakino holoʻokoʻa, a me nā ʻano maʻi maʻi i ke koho ʻana i ka mālama ʻana.

Hana like nā antibodies monoclonal ʻē aʻe e like me rituximab me ublituximab-xiiy a he mau koho paha i kekahi mau kūlana. Loaʻa paha i kekahi poʻe nā lāʻau lapaʻau hui pū e pili ana i nā lāʻau chemotherapy me nā lāʻau lapaʻau i manaʻo ʻia.

Hāʻawi nā lāʻau lapaʻau waha hou i kapa ʻia ʻo BTK inhibitors i nā koho lapaʻau i hoʻokumu ʻia i ka pill i makemake ʻia e kekahi poʻe ma mua o nā infusions IV. Aia kēia mau lāʻau lapaʻau e like me ibrutinib a me acalabrutinib, e hana ana ma nā ʻano hana like ʻole e hakakā i ka maʻi maʻi.

E kūkākūkā kāu hui mālama ola i nā koho a pau i loaʻa iā ʻoe, me ka noʻonoʻo ʻana i kāu makemake, ke ʻano o ke ola, a me nā pono olakino e hana i ka hoʻolālā lapaʻau kūpono loa.

He ʻOi aku ka maikaʻi o Ublituximab-xiiy ma mua o Rituximab?

He mau lapaʻau maikaʻi ʻo Ublituximab-xiiy a me rituximab no CLL a me SLL, akā he mau ʻokoʻa ko lākou e hiki ke hana i kekahi i ʻoi aku ka kūpono iā ʻoe ma mua o kekahi. Hana nā lāʻau ʻelua ma ka pahuhopu ʻana i ka protein CD20 like ma nā pūnaewele maʻi maʻi.

Hōʻike kekahi mau haʻawina e hana wikiwiki paha ʻo ublituximab-xiiy ma mua o rituximab i ka hoʻomaʻemaʻe ʻana i nā pūnaewele maʻi maʻi mai ke koko. Hiki nō hoʻi ke hana i nā hopena infusion liʻiliʻi i kekahi poʻe maʻi, ʻoiai hiki i nā lāʻau ʻelua ke hana i nā hopena ʻaoʻao like.

ʻO ke koho ma waena o kēia mau lāʻau lapaʻau e hilinaʻi pinepine ana i nā mea e like me kāu ʻinikua, ka ʻike o ke kikowaena lapaʻau, a me ka ʻōlelo aʻoaʻo a kāu kauka e pili ana i kāu hihia kikoʻī. Ua manaʻo ʻia nā mea ʻelua he mau koho maikaʻi no ka mālama ʻana i nā maʻi maʻi koko.

E kōkua kāu oncologist iā ʻoe e hoʻomaopopo i ka lāʻau lapaʻau e hana maikaʻi loa no kāu kūlana kikoʻī, me ka noʻonoʻo ʻana i kāu mōʻaukala olakino a me nā pahuhopu lapaʻau.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Ublituximab-xiiy

He Palekana ʻo Ublituximab-xiiy no ka poʻe me ka maʻi diabetes?

Hiki ke hoʻohana palekana ʻia ʻo Ublituximab-xiiy i ka poʻe me ka maʻi diabetes, akā pono ʻoe e nānā pono i kāu pae kōpaʻa koko i ka wā o ka lapaʻau. ʻAʻole pili pololei ka lāʻau lapaʻau i ke kōpaʻa koko, akā hiki i ke koʻikoʻi o ka lapaʻau maʻi maʻi a me kekahi mau lāʻau mua ke hoʻopili i ka mālama glucose.

E hana pū kāu hui mālama ola me ʻoe e hoʻoponopono i kāu mau lāʻau diabetes inā pono a nānā i nā loli i kāu mau hiʻohiʻona kōpaʻa koko. He mea nui e hoʻomau i ka lawe ʻana i kāu mau lāʻau diabetes e like me ka mea i kauoha ʻia ke ʻole e haʻi pololei kāu kauka iā ʻoe.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Ublituximab-xiiy?

No ka mea, hāʻawi ʻia ʻo ublituximab-xiiy i kahi hoʻonohonoho mālama ola i mālama ʻia, he mea maʻamau loa ka overdoses. Ana ʻia ka lāʻau lapaʻau a hāʻawi ʻia e nā poʻe loea i hoʻomaʻamaʻa ʻia e nānā i ka nui pololei āu e loaʻa ai.

Inā he hopohopo kāu e pili ana i kāu mahele lāʻau a i ʻole ʻike i nā hōʻailona ʻokoʻa ma hope o ka mālama ʻana, e kelepona koke i kāu hui mālama ola. Hiki iā lākou ke loiloi i kou kūlana a hāʻawi i ka mālama kūpono inā pono.

He aha kaʻu e hana ai inā haʻalele au i kahi mahele lāʻau o Ublituximab-xiiy?

Inā haʻalele ʻoe i kahi manawa hoʻopaʻa ʻia no ka hoʻokomo ʻana, e kelepona i kāu hui mālama ola i ka hiki wawe e hoʻonohonoho hou. E hoʻoholo lākou i ka manawa kūpono no kāu mālama ʻana e hiki mai ana e pili ana i ka nui o ka manawa i hala a me kāu papa hana mālama.

Mai ho'āʻo e