He aha ʻo Venetoclax: Nā Hoʻohana, Nā Ana, Nā ʻAoʻao ʻAoʻao a me nā mea hou aku

He lāʻau lapaʻau maʻi ʻaʻai ʻo Venetoclax e kōkua ana i ka mālama ʻana i kekahi mau ʻano maʻi ʻaʻai koko ma ka pale ʻana i nā protein e mālama ana i nā pūnaewele maʻi ʻaʻai e ola ana. Hana ʻokoʻa kēia lāʻau lapaʻau waha mai ka chemotherapy kuʻuna, e hāʻawi ana i kahi ala pololei e hakakā ai i nā maʻi ʻaʻai koko kikoʻī e like me ka maʻi lymphocytic leukemia a me ka maʻi myeloid leukemia.

He aha ʻo Venetoclax?

He lāʻau lapaʻau kauka ʻo Venetoclax e pili ana i kahi papa o nā lāʻau i kapa ʻia ʻo BCL-2 inhibitors. Hana ia ma ka ʻimi ʻana a me ka pale ʻana i kahi protein kikoʻī i kapa ʻia ʻo BCL-2 e kōkua ana i nā pūnaewele maʻi ʻaʻai e ola a hoʻonui i kou kino.

E noʻonoʻo iā BCL-2 ma ke ʻano he pale pale e pale ai i nā pūnaewele maʻi ʻaʻai mai ka make maoli ʻana. Wehe ʻo Venetoclax i kēia pale, e ʻae ana i nā pūnaewele maʻi ʻaʻai e make e like me ka mea e pono ai. ʻO kēia ala i manaʻo ʻia e kālele ana ka lāʻau lapaʻau i nā pūnaewele maʻi ʻaʻai ma mua o ka hoʻopilikia ʻana i nā pūnaewele e mahele wikiwiki ana e like me ka chemotherapy kuʻuna.

Hele mai ka lāʻau lapaʻau ma ke ʻano o nā papa waha āu e lawe ai ma ka waha, e maʻalahi ai ka mālama ʻana ma mua o ka chemotherapy intravenous. E kauoha kāu kauka iā venetoclax ma ke ʻano he ʻāpana o kahi hoʻolālā mālama maʻi ʻaʻai piha i hoʻolālā ʻia i kou kūlana kikoʻī.

No ke aha e hoʻohana ʻia ai ʻo Venetoclax?

Hoʻomaʻamaʻa ʻo Venetoclax i kekahi mau ʻano maʻi ʻaʻai koko, ʻo ka maʻi lymphocytic leukemia (CLL) a me ka maʻi myeloid leukemia (AML). Hiki i kāu kauka ke kauoha i kēia lāʻau lapaʻau ke hana ʻole nā ​​lāʻau lapaʻau ʻē aʻe a i ʻole ma ke ʻano he lāʻau lapaʻau laina mua i kekahi mau kūlana.

No ka maʻi lymphocytic leukemia, kōkua ʻo venetoclax i ka mālama ʻana i ka maʻi ma ka hōʻemi ʻana i ka helu o nā keʻokeʻo keʻokeʻo maʻamau i kou kino. Hiki i kēia ke kōkua i ka hōʻemi ʻana i nā lymph node pehu, e hōʻemi i ka luhi, a e hoʻomaikaʻi i kou maikaʻi o ke ola.

I ka maʻi leukemia myeloid acute, hui pinepine ʻia ʻo venetoclax me nā lāʻau lapaʻau ʻē aʻe e kōkua i ka hoʻokō ʻana i ka remission. Hiki i kēia hui pū ʻana ke kōkua nui i nā mākua kahiko a i ʻole ka poʻe i hiki ʻole ke ʻae i ka chemotherapy ikaika.

Na kāu oncologist e hoʻoholo inā kūpono ʻo venetoclax no kāu ʻano kikoʻī a me ke kahua o ka maʻi kanesa koko. E noʻonoʻo lākou i nā mea e like me kou olakino holoʻokoʻa, nā lāʻau lapaʻau i hala, a me nā ʻano genetic o kāu mau cell cancer.

Pehea e Hana ai ʻo Venetoclax?

Hana ʻo Venetoclax ma ka pale ʻana i ka protein BCL-2, e hana ana e like me ka hōʻailona ola no nā cell cancer. Ua manaʻo ʻia kēia lāʻau lapaʻau he lāʻau lapaʻau ikaika a i manaʻo ʻia e hoʻouka pono i nā hana a nā cell cancer e hoʻohana ai e ola.

Ke nalowale nā cell cancer i kā lākou pale BCL-2, hele lākou i kahi hana make cell maoli i kapa ʻia ʻo apoptosis. Hana mālie kēia hana i ka manawa, ʻo ia ke kumu e pono ai ʻoe i nā hoʻokolohua koko maʻamau e nānā i ka maikaʻi o ka hana ʻana o ka lāʻau lapaʻau.

He ikaika loa ka lāʻau lapaʻau i hoʻohālikelike ʻia me kekahi mau lāʻau lapaʻau cancer waha ʻē aʻe. Hiki iā ia ke hoʻoulu i nā loli wikiwiki i kāu helu cell koko, ʻoiai ke hoʻomaka mua ʻoe i ka lāʻau lapaʻau. ʻO ia ke kumu e hoʻomaka ai kāu kauka iā ʻoe ma kahi haʻahaʻa haʻahaʻa a hoʻonui mālie iā ia i nā pule he nui.

ʻAʻole like me ka chemotherapy ākea e pili ana i nā ʻano cell he nui, hoʻopaʻa pono ʻo venetoclax i nā cell e hilinaʻi nui ana iā BCL-2 no ke ola. Hiki i kēia ala i manaʻo ʻia ke ʻoi aku ka maikaʻi me ka hiki ke hana i nā hopena ʻaoʻao liʻiliʻi ma mua o ka chemotherapy kuʻuna.

Pehea wau e lawe ai iā Venetoclax?

E lawe iā venetoclax e like me ke kauoha a kāu kauka, maʻamau hoʻokahi manawa i ka lā me ka meaʻai a me ka wai. ʻO ka lawe ʻana me ka ʻai e kōkua i kou kino e komo pono i ka lāʻau lapaʻau a hoʻemi i ka pilikia o ka ʻōpū.

E ale i nā papa holoʻokoʻa me ka ʻole o ka ʻoki ʻana, ka nau ʻana, a i ʻole ka wāwahi ʻana iā lākou. Inā pilikia ʻoe i ka ale ʻana i nā pila, e kamaʻilio me kāu kauka e pili ana i nā ala ʻē aʻe, akā ʻaʻole loa e hoʻololi i nā papa iā ʻoe iho.

E hoʻomaka kāu kauka iā ʻoe me kahi mahele haʻahaʻa a e hoʻonui mālie ia i nā pule he nui. Kōkua kēia papa hana piʻi i ka hōʻemi ʻana i nā hopena ʻaoʻao a hiki i kou kino ke hoʻoponopono i ka lāʻau lapaʻau me ka palekana.

E hoʻāʻo e lawe i ka venetoclax i ka manawa like i kēlā me kēia lā e mālama i nā pae kūlike i loko o kou kino. Inā ʻoe e lawe nei i nā lāʻau lapaʻau ʻē aʻe, e hāʻawi kāu kauka i nā ʻōlelo kuhikuhi manawa kikoʻī e pale aku i nā pilina kūpono.

Ma mua o ka hoʻomaka ʻana i ka lāʻau, e ʻai i ka meaʻai māmā a i ʻole ka ʻai māmā. E hōʻalo i ka hua waina a me ka wai hua waina, no ka mea hiki iā lākou ke hoʻonui i nā hopena o ka lāʻau lapaʻau a hiki ke hana i nā hopena ʻaoʻao weliweli.

Pehea ka lōʻihi e pono ai wau e lawe i ka Venetoclax?

ʻO ka lōʻihi o ka mālama ʻana i ka venetoclax e ʻokoʻa ana ma muli o kāu ʻano maʻi maʻi kikoʻī a me ka maikaʻi o kāu pane ʻana i ka lāʻau lapaʻau. Lawe ka hapa nui o nā kānaka iā ia no ka liʻiliʻi o kekahi mau mahina, a pono paha kekahi e hoʻomau no nā makahiki.

No ka maʻi leukemia lymphocytic maʻi, maʻamau ka mālama ʻana i 12 a 24 mau mahina ke hoʻohana ʻia wale nō, a i ʻole nā manawa pōkole ke hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe. E nānā kāu kauka i kāu helu koko a me ka pane holoʻokoʻa e hoʻoholo ai i ka lōʻihi o ka lāʻau lapaʻau.

Me ka maʻi leukemia myeloid acute, pili ka lōʻihi o ka mālama ʻana inā loaʻa iā ʻoe ke kala ʻana a me kou kūlana olakino holoʻokoʻa. Hiki i kekahi poʻe ke lawe i ka venetoclax no nā wā lōʻihi e mālama i kā lākou pane.

E loiloi mau kāu oncologist i kāu holomua ma o nā hoʻokolohua koko, nā scans kiʻi, a me nā hoʻokolohua kino. E hoʻoponopono lākou i kāu hoʻolālā lapaʻau e pili ana i ka maikaʻi o ka pane ʻana o ka maʻi maʻi a me nā hopena ʻaoʻao āu e ʻike ai.

Mai hooki i ka lawe ʻana i ka venetoclax me ka kū ʻole me ka kūkākūkā ʻole me kāu kauka mua. ʻOiai inā ʻoe e ʻoi aku ka maikaʻi, ʻo ka hoʻōki ʻana i ka lāʻau lapaʻau ma mua o ka manawa hiki ke ʻae i ka maʻi maʻi e hoʻi mai a i ʻole e ʻino.

He aha nā hopena ʻaoʻao o Venetoclax?

Hiki i ka Venetoclax ke hana i nā hopena ʻaoʻao mai ka maʻalahi a i ka koʻikoʻi, ʻoiai ʻaʻole e ʻike nā kānaka a pau iā lākou. Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao me ka nānā pono ʻana a me ke kākoʻo mai kāu hui mālama ola.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia ka luhi, ka nausea, ka maʻi palahī, a me nā loli i kāu helu ʻana i nā cell koko. Hoʻomaikaʻi pinepine kēia mau hopena i ka wā e hoʻoponopono ai kou kino i ka lāʻau lapaʻau i nā pule mua o ka mālama ʻana.

Nā Hopena ʻAoʻao Maʻamau

Eia nā hopena ʻaoʻao i ʻike ʻia e nā kānaka he nui, a ʻoiai hiki iā lākou ke hōʻoluʻolu ʻole, hiki ke mālama ʻia me ke alakaʻi ʻana a kāu kauka:

• Ka luhi a me ka nāwaliwali e pili ana i kāu mau hana i kēlā me kēia lā
• Nausea a me ka luaʻi ʻana, ʻoi loa i nā pule mua
• Maʻi palahī e hiki ke hele mai ka maʻalahi a i ka maʻi
• Nā maʻi hanu luna e like me ke anu
• Hoʻemi ʻia ka ʻai a me nā loli kaumaha
• Nā poʻo a me ka dizziness
• ʻO ka ʻeha ʻiʻo a me ka hui
• Paʻa

E lilo pinepine kēia mau hōʻailona i mea hiki ke mālama ʻia i ka wā e hoʻopili ai kou kino i ka lāʻau lapaʻau. Hiki i kāu hui mālama ola ke hāʻawi i nā lāʻau lapaʻau a me nā hoʻolālā e kōkua i ka hōʻemi ʻana i kēia mau hopena.

Nā Hopena ʻAoʻao Koʻikoʻi

ʻOiai ʻaʻole maʻamau, pono kekahi mau hopena ʻaoʻao i ka lāʻau lapaʻau koke no ka mea hiki iā lākou ke hoʻoweliweli i ke ola inā ʻaʻole i mālama koke ʻia:

• ʻO ka maʻi lysis tumor - ka wāwahi wikiwiki ʻana o nā cell maʻi maʻi e hiki ke hoʻopilikia i kou mau puʻupaʻa a me ka puʻuwai
• Hoʻemi nui i nā cell koko keʻokeʻo, e hoʻonui ana i ka pilikia o ka maʻi
• Nā helu platelet haʻahaʻa e alakaʻi ana i ke kahe ʻana a i ʻole ka ʻeha
• ʻO ka anemia koʻikoʻi e hana ana i ka luhi nui a me ka pōkole o ka hanu
• Nā hōʻailona o ka maʻi koʻikoʻi e like me ke kuni, nā anu, a i ʻole ka ʻū
• Ke kahe ʻana mai nā ʻāʻī, ka ihu, a i ʻole nā wahi ʻē aʻe
• Nausea a me ka luaʻi ʻana e pale ana iā ʻoe mai ka mālama ʻana i ka meaʻai

E kāhea koke i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona. Hiki i ka hana wikiwiki ke pale i nā pilikia a kōkua iā ʻoe e hoʻomau i ka mālama ʻana me ka palekana.

Nā hopena ʻaoʻao kakaʻikahi akā koʻikoʻi

Loaʻa kekahi mau hopena ʻaoʻao i ka wā pinepine ʻole akā he mea nui e ʻike no ka mea e koi ana lākou i ka mālama olakino kūikawā:

• Nā loli o ka puʻuwai e hiki ke hoʻoulu i ka puʻuwai a i ʻole ka maʻi
• Nā pilikia ate koʻikoʻi i hōʻike ʻia e ka melemele o ka ʻili a i ʻole nā maka
• Ka hana ʻole o ka puʻupaʻa e hiki ke hoʻololi i ka mimi
• Nā hopena maʻi maʻi koʻikoʻi me ka ʻōpala, ka hanu ʻana, a i ʻole ka pehu
• Nā maʻi maʻi lua, ʻoiai he kakaʻikahi kēia
• Nā hōʻailona neurological koʻikoʻi e like me ka huikau a i ʻole nā hopu

ʻOiai ʻaʻole maʻamau kēia mau hopena, nānā kāu hui mālama ola iā lākou ma o nā hoʻokolohua koko maʻamau a me nā nānā ʻana. Hiki i ka ʻike mua ke ʻae i ka mālama wikiwiki a me nā hopena maikaʻi.

ʻO wai ka mea pono ʻole e lawe iā Venetoclax?

ʻAʻole kūpono ʻo Venetoclax no nā mea a pau, a hiki i kekahi mau maʻi olakino a i ʻole nā lāʻau lapaʻau ke palekana ʻole iā ʻoe. E nānā pono kāu kauka i kāu moʻolelo olakino ma mua o ke kau ʻana i kēia lāʻau.

ʻAʻole pono ʻoe e lawe iā venetoclax inā he maʻi ʻoe iā ia a i ʻole kekahi o kāna meaʻai. Pono paha nā kānaka me nā pilikia ate a i ʻole nā puʻupaʻa i nā hoʻoponopono ʻana i ka maʻi a i ʻole nā lāʻau lapaʻau ʻē aʻe.

Inā hāpai ʻoe a i ʻole e hānai ana i ka waiū, hiki i ka venetoclax ke hōʻino i kāu pēpē a pono e pale ʻia. Pono nā wahine o ka makahiki hānau e hoʻohana i ka contraception pono i ka wā o ka mālama ʻana a no kekahi manawa ma hope o ka hoʻōki ʻana i ka lāʻau.

ʻO nā kānaka e lawe ana i kekahi mau lāʻau lapaʻau, ʻo ia hoʻi nā mea pale CYP3A ikaika e like me kekahi mau lāʻau antifungal, ʻaʻole paha he moho no venetoclax ma muli o nā pilina lāʻau weliweli. E nānā kāu kauka i kāu mau lāʻau lapaʻau i kēia manawa ma mua o ka hoʻomaka ʻana i ka mālama ʻana.

ʻO ka poʻe me nā maʻi koʻikoʻi, pono lākou e kali a hiki i ka wā e mālama ʻia ai ka maʻi ma mua o ka hoʻomaka ʻana i ka venetoclax. Hiki i ka lāʻau lapaʻau ke hoʻopilikia hou i kāu ʻōnaehana pale, e paʻakikī ai ka hakakā ʻana i nā maʻi.

Nā inoa inoa o Venetoclax

Kūʻai ʻia ʻo Venetoclax ma lalo o ka inoa inoa Venclexta ma ʻAmelika Hui Pū ʻIa a me Venclyxto ma nā ʻāina ʻē aʻe. Loaʻa i nā mea ʻelua ka mea hana like a hana like.

Hana ʻia ka lāʻau lapaʻau e AbbVie a me Genentech, e hana pū ana e hōʻoia i ka maikaʻi a me ka loaʻa. Hiki i kāu hale kūʻai lāʻau lapaʻau ke lawe i kekahi inoa inoa ma muli o kā lākou hoʻonohonoho mea kūʻai.

ʻAʻole i loaʻa nā mana generic o venetoclax, no laila e loaʻa iā ʻoe ka lāʻau lapaʻau inoa inoa me ka nānā ʻole i ka inoa e ʻike ʻia ma ka lepili. Noho like ka pono a me ka palekana ma waena o nā inoa inoa like ʻole.

Nā koho ʻē aʻe o Venetoclax

Nui nā lāʻau lapaʻau ʻē aʻe no nā maʻi koko, ʻoiai ʻo ke koho maikaʻi loa e pili ana i kāu ʻano maʻi kikoʻī, ke kahua, a me ke olakino holoʻokoʻa. E noʻonoʻo kāu oncologist i kēia mau koho inā ʻaʻole kūpono ka venetoclax iā ʻoe.

No ka leukemia lymphocytic maʻi, nā koho ʻē aʻe e pili ana i ka ibrutinib (Imbruvica), acalabrutinib (Calquence), a me nā hui chemotherapy kuʻuna e like me FCR a i ʻole BR. Loaʻa i kēlā me kēia me nā ʻano hopena ʻaoʻao like ʻole a me nā helu pono.

I ka leukemia myeloid acute, hiki i nā koho ʻē aʻe ke komo i nā regimens chemotherapy ikaika, nā lāʻau lapaʻau i manaʻo ʻia e like me FLT3 inhibitors, a i ʻole ka hoʻololi ʻana i ke keʻena stem ma muli o kāu kūlana kikoʻī.

Hiki ke noʻonoʻo ʻia nā lāʻau lapaʻau kahiko e like me chlorambucil a i ʻole rituximab no ka poʻe ʻaʻole hiki ke ʻae i nā lāʻau lapaʻau hou. E kaupaona kāu kauka i nā pōmaikaʻi a me nā pilikia o kēlā me kēia koho e hana i ka hoʻolālā lapaʻau maikaʻi loa no ʻoe.

Hiki i nā hoʻokolohua lapaʻau ke hāʻawi i ke komo ʻana i nā lāʻau lapaʻau hoʻokolohua hou. Hiki i kāu oncologist ke kūkākūkā inā kūpono kekahi mau hoʻokolohua i kēia manawa no kāu maʻi kikoʻī.

Ua ʻOi aku ka maikaʻi o Venetoclax ma mua o Ibrutinib?

He mau lapaʻau pono ʻo Venetoclax a me ibrutinib no ka leukemia lymphocytic maʻi, akā hana lākou ma nā ʻano like ʻole a loaʻa nā pono like ʻole. Aia ka koho "ʻoi aku ka maikaʻi" ma kāu mau kūlana a me nā makemake.

Hāʻawi ʻo Venetoclax i ka pono o ka lōʻihi lapaʻau paʻa, maʻamau 12-24 mahina, ma hope o ia mea hiki iā ʻoe ke hooki i ka lawe ʻana i ka lāʻau. Lawe mau ʻia ʻo Ibrutinib a hiki i ka wā e pau ai ka hana a i ʻole e hana i nā hopena ʻaoʻao hiki ʻole ke ʻae ʻia.

Ma ke ʻano o nā hopena ʻaoʻao, hana pinepine ʻo venetoclax i ka nausea a me nā pilikia digestive, ʻoiai ʻo ibrutinib e hana pinepine i ka ʻeha hui, nā pilikia o ka puʻuwai, a me nā pilikia koko. E noʻonoʻo kāu kauka i ka mea e hiki ke mālama ʻia no ʻoe.

Hōʻike nā haʻawina hou e hiki i nā hui venetoclax ke hāʻawi i nā hoʻihoʻi hohonu i kekahi poʻe maʻi, e alakaʻi ana i nā manawa lōʻihi me ka ʻole o ka lapaʻau. Eia naʻe, ua loaʻa ʻo ibrutinib no ka lōʻihi a loaʻa nā ʻikepili palekana lōʻihi.

E noʻonoʻo kāu kauka i nā mea e like me kou makahiki, nā kūlana olakino ʻē aʻe, nā lapaʻau mua, a me nā makemake pilikino i ka wā e ʻōlelo ai ma waena o kēia mau lāʻau. Ua manaʻo ʻia lāua he mau koho lapaʻau maikaʻi loa no ka leukemia lymphocytic maʻi.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana iā Venetoclax

He Palekana ʻo Venetoclax no ka poʻe me ka maʻi puʻuwai?

Hiki ke hoʻohana ʻia ʻo Venetoclax i ka poʻe me ka maʻi puʻuwai, akā pono ka nānā pono ʻana a me nā hoʻoponopono ʻana i ka lāʻau. Hiki i ka lāʻau ke hoʻopilikia i kou puʻuwai a hiki ke launa pū me nā lāʻau puʻuwai āu e lawe nei.

E hana pū kāu cardiologist a me oncologist e nānā i kāu hana puʻuwai i ka wā o ka lapaʻau. Hiki iā lākou ke ʻōlelo i nā electrocardiograms maʻamau (ECGs) e nānā i kou puʻuwai a hoʻoponopono i kāu hoʻolālā lapaʻau inā pono.

Inā he pilikia nui kou puʻuwai, hiki i kāu kauka ke hoʻomaka iā ʻoe ma kahi lāʻau haʻahaʻa a i ʻole e nānā pinepine iā ʻoe. ʻO nā pōmaikaʻi o ka mālama ʻana i kāu maʻi maʻi maʻi e ʻoi aku ka nui ma mua o nā pilikia o ka puʻuwai, akā ua loiloi ʻia kēlā me kēia kūlana.

He aha kaʻu e hana ai inā ua lawe hewa au i ka nui o Venetoclax?

Inā ua lawe hewa ʻoe i ka nui o venetoclax ma mua o ka mea i kuhikuhi ʻia, e hoʻokaʻaʻike koke i kāu kauka a i ʻole ke kikowaena hoʻomalu lāʻau make, ʻoiai inā maikaʻi ʻoe. ʻO ka lawe ʻana i ka nui hiki ke hoʻoulu i nā hāʻule weliweli i kāu helu keʻena koko a i ʻole ka maʻi lysis tumor.

Mai ho'āʻo e hoʻokomo iā ʻoe iho i ka luaʻi a i ʻole e lawe i nā lāʻau lapaʻau hou e kūʻē i ka overdose. Akā, e kelepona koke i kāu mea mālama ola a i ʻole e hele i ka lumi pilikia inā kuhikuhi ʻia.

E lawe mai i kāu hue lāʻau me ʻoe i hiki i nā mea mālama ola ke ʻike pololei i ka mea a me ka nui āu i lawe ai. Hiki iā lākou ke makemake e nānā pono iā ʻoe a holo i nā hoʻokolohua koko e nānā i nā pilikia.

He aha kaʻu e hana ai inā ua hala au i kahi lāʻau o Venetoclax?

Inā ua hala ʻoe i kahi lāʻau a ua hala ma lalo o 8 mau hola mai kou manawa maʻamau, e lawe i ka lāʻau i hala me ka meaʻai i ka wā e hoʻomanaʻo ai ʻoe. Inā ua hala ma mua o 8 mau hola, e lele i ka lāʻau i hala a lawe i kāu lāʻau i hoʻonohonoho ʻia.

Mai lawe i ʻelua lāʻau i ka manawa hoʻokahi e hoʻopiha ai i kahi lāʻau i hala, no ka mea, hiki i kēia ke hoʻonui i kou pilikia o nā hopena ʻaoʻao koʻikoʻi. ʻOi aku ka maikaʻi o ka lele ʻana i hoʻokahi lāʻau ma mua o ka pālua.

Inā poina pinepine ʻoe i nā lāʻau, e noʻonoʻo e hoʻonohonoho i nā ʻōhua kelepona a i ʻole e hoʻohana i kahi mea hoʻonohonoho pila e kōkua iā ʻoe e hoʻomanaʻo. He mea nui ka dosing mau no ka hana pono ʻana o ka lāʻau.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Venetoclax?

Hiki iā ʻoe ke hooki i ka lawe ʻana iā venetoclax i ka wā e hoʻoholo ai kāu kauka he palekana ke hana pēlā, ma hope o ka pau ʻana o kāu papa lapaʻau i kuhikuhi ʻia a i ʻole inā pau ka hana pono ʻana o ka lāʻau. Mai hooki i ka lawe ʻana iā ia ma kāu iho, ʻoiai inā maikaʻi ʻoe.

No ka leukemia lymphocytic maʻi, hiki i ka hapa nui o nā kānaka ke hooki ma hope o 12-24 mau mahina inā loaʻa iā lākou kahi pane maikaʻi. E hoʻohana kāu kauka i nā hoʻokolohua koko a me nā loiloi ʻē aʻe e hoʻoholo ai i ka manawa kūpono e hooki ai.

Pono paha kekahi poʻe e hoʻomau i ka mālama ʻana no ka lōʻihi inā ʻaʻole i pane kūpono kā lākou maʻi maʻi a i ʻole inā he mau hiʻohiʻona pilikia kiʻekiʻe ko lākou. E kūkākūkā kāu oncologist i ka manawa maikaʻi loa no kāu kūlana kikoʻī.

Hiki iaʻu ke inu i ka waiʻona i ka wā e lawe ana i ka Venetoclax?

Pono ʻoe e kaupalena i ka ʻai ʻana i ka waiʻona i ka wā e lawe ana i ka venetoclax, no ka mea, hiki i ka waiʻona ke hoʻonui i kekahi mau hopena ʻaoʻao a hiki ke hoʻopilikia i ka pono o ka lāʻau. E kūkākūkā i kāu hoʻohana ʻana i ka waiʻona me kāu kauka e loaʻa nā ʻōlelo aʻoaʻo pilikino.

Hiki i ka waiʻona ke hoʻonui i ka nausea, ka ʻūlū, a me ke kaumaha o ke ake, hiki ke hoʻohui i nā hopena ʻaoʻao o ka venetoclax. Hiki nō hoʻi ke hoʻopilikia i kāu ʻōnaehana pale, e hoʻolilo iā ʻoe i mea maʻalahi i nā maʻi.

Inā koho ʻoe e inu i kekahi manawa, e hana me ka maʻalahi a e nānā i ke ʻano o kou kino. ʻIke kekahi poʻe ʻaʻole lākou e ʻae i ka waiʻona i ka wā o ka mālama ʻana i ka maʻi maʻi, aʻo nā mea ʻē aʻe hiki ke leʻaleʻa i nā mea liʻiliʻi me ka ʻole o nā pilikia.