He aha ʻo Vincristine: Nā Hoʻohana, Nā Ana, Nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau chemotherapy ikaika ʻo Vincristine a nā kauka e hoʻohana ai e mālama i nā ʻano maʻi maʻi like ʻole, me ka leukemia, lymphoma, a me kekahi mau maʻi maʻi kamaliʻi. No kēia lāʻau i kahi hui i kapa ʻia ʻo vinca alkaloids, e hana ana ma ka hoʻōki ʻana i nā cell maʻi mai ka mahele a me ka ulu ʻana. E loaʻa iā ʻoe ka vincristine ma o ka laina IV pololei i loko o kou kahe koko, e ʻae ana iā ia e hiki i nā cell maʻi ma kou kino a pau.

He aha ʻo Vincristine?

He lāʻau chemotherapy ʻo Vincristine i hana ʻia mai ka mea kanu periwinkle e kuhikuhi pono ana i nā cell e mahele wikiwiki ana. Hana ia ma ka hoʻopilikia ʻana i ka hiki o ka cell ke kaʻawale i ka wā o ka mahele, kahi e hoʻōki pono ai i nā cell maʻi mai ka hoʻonui ʻana. ʻO kēia ala i kuhikuhi ʻia e hana pono ai ia i kekahi mau maʻi maʻi koko a me nā ʻōpū paʻa.

Ua hoʻohana maikaʻi ʻia ka lāʻau lapaʻau i ka mālama ʻana i ka maʻi maʻi no nā makahiki he nui a ke waiho nei i kahi lāʻau lapaʻau kumu no nā maʻi maʻi pediatric he nui. E helu pono kāu hui oncology i kāu ana e pili ana i kou wahi kino a me ke ʻano o ka maʻi maʻi e hōʻoia ai e loaʻa iā ʻoe ka lāʻau lapaʻau maikaʻi loa me ka hōʻemi ʻana i nā pilikia.

No ke aha e hoʻohana ʻia ai ʻo Vincristine?

Mālama ʻo Vincristine i nā ʻano maʻi maʻi like ʻole, me nā kauka e kauoha pinepine ana iā ia no nā maʻi maʻi e pili ana i ke koko a me kekahi mau maʻi kamaliʻi. He mea pono loa ia i nā maʻi maʻi kahi e mahele wikiwiki ai nā cell, e lilo ana ia i mea kaua waiwai i kāu arsenal lapaʻau.

Eia nā kūlana nui kahi e hōʻoia ai ʻo vincristine i ke kōkua nui:

• Laukemika lymphoblastic acute (ALL) - ka laukemika kamaliʻi maʻamau loa
• Laukemika myeloid acute (AML) - pili i nā keʻena koko keʻokeʻo
• Lymphoma o Hodgkin - ka maʻi ʻaʻai o ka ʻōnaehana lymphatic
• Lymphoma ʻaʻole o Hodgkin - nā ʻano maʻi ʻaʻai lymph node like ʻole
• Tumor o Wilms - he maʻi ʻaʻai kīkī e pili ana i nā keiki
• Neuroblastoma - he maʻi ʻaʻai e ulu ana i loko o ka ʻiʻo nerve
• Rhabdomyosarcoma - he maʻi ʻaʻai ʻiʻo palupalu
• Nā maʻi ʻaʻai lolo - kekahi mau ʻano i nā keiki a me nā pākeke

Hiki nō hoʻi i kāu kauka ke hoʻohana i ka vincristine no nā maʻi ʻaʻai laha ʻole a i ʻole ma ke ʻano he ʻāpana o nā haʻawina noiʻi e ʻimi ana i nā hui lapaʻau hou. ʻO ka hoʻoholo e hoʻokomo i ka vincristine i kāu hoʻolālā lapaʻau e hilinaʻi ana i kāu ʻano maʻi ʻaʻai kikoʻī, ke kahua, a me ke kūlana olakino holoʻokoʻa.

Pehea e hana ai ka Vincristine?

Hana ʻo Vincristine ma ka ʻimi ʻana i kahi ʻāpana kikoʻī o nā keena i kapa ʻia ʻo microtubules, he mau alaloa liʻiliʻi e kōkua ana i nā keena e mahele pono. Ke hoʻāʻo nā keena maʻi ʻaʻai e mahele i ʻelua mau keena hou, ālai ʻo vincristine i kēia mau alaloa, e hoʻōki loa i ke kaʻina hana mahele. ʻO kēia hana e hana ai i mea kūpono loa i nā keena maʻi ʻaʻai e ulu wikiwiki ana.

E noʻonoʻo e like me ke kau ʻana i nā roadblocks i ka wā hola wikiwiki - ua hoʻopilikia ʻia ke kahe kaʻa maʻamau, a ʻaʻole hiki i nā keena ke hoʻopau i kā lākou huakaʻi e lilo i ʻelua mau keena kaʻawale. No ka mea, ʻoi aku ka pinepine o ka mahele ʻana o nā keena maʻi ʻaʻai ma mua o nā keena maʻamau, ʻoi aku ka nui o ka hopena o kēia hoʻopilikia.

Ua manaʻo ʻia ʻo Vincristine he lāʻau chemotherapy ikaika, ʻo ia hoʻi hiki iā ia ke loaʻa nā hopena koʻikoʻi i kou kino. Eia naʻe, ʻo kona ikaika hoʻi e hana nui ai i nā ʻano maʻi ʻaʻai he nui, ʻo ia ke kumu i koho ai kāu hui lapaʻau iā ia ma ke ʻano he ʻāpana o kāu hoʻolālā lapaʻau.

Pehea e lawe ai au i ka Vincristine?

E loaʻa iā ʻoe ka vincristine ma o ka laina IV wale nō ma kahi haukapila a i ʻole ke keʻena lapaʻau - ʻaʻole loa ma ke ʻano he pila a i ʻole ka pahu i loko o kou iwi kuamoʻo. E nānā pālua mau kāu hui mālama ola i ka hoʻokomo pono ʻia ʻana o ka IV i loko o kou vein ma mua o ka hāʻawi ʻana iā ʻoe i ka lāʻau lapaʻau. Kōkua kēia hana mālama i ka hōʻoia ʻana i kou palekana a me ka pono o ka lāʻau lapaʻau.

Lawe maʻamau ka infusion i kekahi mau minuke wale nō, akā pono paha ʻoe e noho no ka nānā ʻana ma hope. E nānā pono kāu kahu maʻi i ke kahua IV i ka wā o ka mālama ʻana e hōʻoia i ka hele pololei ʻana o ka lāʻau lapaʻau i loko o kou kahe koko a ʻaʻole e kahe i loko o nā ʻiʻo a puni.

ʻAʻole pono ʻoe e hoʻokē ʻai ma mua o ka loaʻa ʻana o ka vincristine, a hiki iā ʻoe ke ʻai maʻamau i nā lā lapaʻau. Eia naʻe, ʻo ka noho ʻana i ka wai maikaʻi ma ka inu ʻana i ka wai nui ma mua a ma hope o kāu infusion hiki ke kōkua i kou kino e hana i ka lāʻau lapaʻau me ka ʻoi aku ka maikaʻi. E hāʻawi kāu hui mālama i nā ʻōlelo kikoʻī e pili ana i ka ʻai ʻana a me ka inu ʻana ma muli o kāu mau lāʻau lapaʻau ʻē aʻe.

Pehea ka lōʻihi e lawe ai au i ka Vincristine?

He ʻokoʻa nui ka lōʻihi o ka mālama ʻana i ka vincristine ma muli o kāu ʻano maʻi maʻi a me ke ʻano o ka mālama ʻana. Loaʻa ka vincristine i ka hapa nui o nā maʻi ma ke ʻano he ʻāpana o kahi hui pū ʻana o ka chemotherapy e hiki ke lōʻihi mai kekahi mau mahina a ʻoi aku ma mua o hoʻokahi makahiki. E wehewehe kāu oncologist i kāu papa manawa lapaʻau i ka wā o kāu kūkākūkā.

Nui nā hoʻolālā lapaʻau e pili ana i nā pōʻaiapuni kahi e loaʻa ai iā ʻoe ka vincristine i hoʻokahi manawa i ka pule no kekahi mau pule, a laila e ukali ʻia e kahi manawa hoʻomaha. No ka laʻana, hiki i nā keiki me ka leukemia lymphoblastic acute ke loaʻa ka vincristine i kēlā me kēia pule i ka wā o kahi pae ikaika, a laila ʻaʻole pinepine i ka wā o ka mālama ʻana i hiki ke hoʻomau a hiki i ʻelua makahiki.

E loiloi mau kāu hui lapaʻau i ka maikaʻi o ka hana ʻana o ka lapaʻau ma o nā hoʻokolohua koko, nā kiʻi kiʻi, a me nā hoʻokolohua kino. Hiki iā lākou ke hoʻoponopono i kāu papa manawa lapaʻau ma muli o ke ʻano o ka pane ʻana o kou kino a inā ʻoe e ʻike i nā hopena ʻaoʻao koʻikoʻi.

He aha nā hopena ʻaoʻao o Vincristine?

Hiki i ka Vincristine ke hana i nā hopena ʻaoʻao like ʻole, mai ka maʻalahi a i ka ʻoi aku ka koʻikoʻi, no ka mea, pili ia i nā pūnaewele maʻi ʻaʻai a me kekahi mau pūnaewele maʻamau i kou kino. ʻO ka hoʻomaopopo ʻana i kēia mau hopena hiki ke kōkua iā ʻoe e ʻike iā lākou i ka wā mua a hana pū me kāu hui mālama ola e mālama pono iā lākou.

ʻO nā hopena ʻaoʻao maʻamau āu e ʻike ai, ʻo ia:

• Nā pilikia o ke aʻalolo (neuropathy) - ka ʻūlū, ka ʻeha, a i ʻole ka nāwaliwali i nā lima a me nā wāwae
• Paʻa - pinepine ka nui a koi i ka mālama ikaika
• Ka nalowale o ka lauoho - maʻamau ka manawa a hiki ke hoʻihoʻi ʻia ma hope o ka mālama ʻana
• Luhi a me ka nāwaliwali
• Hoʻemi ʻia ka ʻai
• Nausea a me ka luaʻi
• Nā ʻeha waha
• Haʻahaʻa keʻokeʻo koko (hoʻonui ʻia ka pilikia o ka maʻi)

Hiki ke mālama ʻia kēia mau hopena maʻamau me ka mālama kūpono a maʻamau e hoʻomaikaʻi ma hope o ka pau ʻana o ka mālama ʻana. Nui nā hoʻolālā a kāu hui mālama ola e kōkua iā ʻoe e ʻoluʻolu i ka wā o ka mālama ʻana.

ʻO nā hopena ʻaoʻao koʻikoʻi akā ʻaʻole maʻamau e koi i ka lāʻau lapaʻau koke:

• ʻO ka pōʻino nui o ke aʻalolo e hana ana i ka nāwaliwali nui a i ʻole ka pilikia o ka hele wāwae
• Nā hōʻailona o ka maʻi (fiva, nā anu, ka ʻūlū mau)
• ʻO ka ʻeha nui o ka ʻōpū a i ʻole ka hiki ʻole ke loaʻa nā neʻe ʻana o ka ʻōpū
• Ka pilikia o ka hanu ʻana a i ʻole ka ʻeha o ka umauma
• Nā hopena maʻi maʻi nui
• Nā loli ʻike a i ʻole nā pilikia lohe
• Nā hopu (rare but possible)

ʻO nā pilikia koʻikoʻi akā kakaʻikahi hiki ke komo i ka pōʻino nui o ke aʻalolo e pili ana i kou hiki ke hele a hoʻohana i kou mau lima maʻamau. Hiki i kekahi poʻe maʻi ke hoʻomohala i kahi maʻi i kapa ʻia ʻo SIADH (syndrome of inappropriate antidiuretic hormone secretion), e pili ana i ke kaulike wai i kou kino.

ʻO wai ka mea pono ʻole e lawe iā Vincristine?

ʻO kekahi mau maʻi a me nā kūlana olakino e hana ai i ka mālama ʻana me ka vincristine i kūpono ʻole a i ʻole e koi ai i nā hana kūikawā. E nānā pono kāu kauka oncologist i kāu moʻolelo olakino e hōʻoia i ka palekana o ka vincristine iā ʻoe ma mua o ka hoʻomaka ʻana i ka mālama ʻana.

ʻAʻole pono ʻoe e loaʻa i ka vincristine inā loaʻa iā ʻoe:

• He maʻi koʻikoʻi e hana nei ʻaʻole i mālama ʻia
• He maʻi ate koʻikoʻi e hoʻopilikia ana i ka hiki o kou kino ke hana i ka lāʻau
• ʻO ka pōʻino o nā aʻalolo koʻikoʻi (peripheral neuropathy)
• ʻO nā hopena maʻi koʻikoʻi i ʻike ʻia i ka vincristine a i ʻole nā lāʻau lapaʻau like
• ʻO kekahi mau maʻi genetic e pili ana i ke ʻano o ka hana ʻana o kou kino i kēia ʻano lāʻau

Pono ka mālama kūikawā inā loaʻa iā ʻoe nā pilikia ate māmā a i ʻole waena, nā pilikia aʻalolo e kū nei, a i ʻole e lawe ana i nā lāʻau lapaʻau e hiki ke hoʻonui i ka pilikia o ka pōʻino o nā aʻalolo. E hoʻoponopono kāu kauka i kāu mahele a i ʻole e nānā pono iā ʻoe i kēia mau kūlana.

ʻAʻole pono nā wahine hāpai e loaʻa i ka vincristine ma muli o ka pōʻino i ka pēpē e ulu nei. Inā ʻoe i ka makahiki hānau keiki, e kūkākūkā kāu hui mālama ola i nā ʻano hana pale hāpai ma mua o ka hoʻomaka ʻana i ka mālama ʻana.

Nā inoa inoa o Vincristine

Loaʻa ka Vincristine ma lalo o nā inoa inoa like ʻole, ʻoiai ke hana like ka mana generic me nā koho branded. Ma ʻAmelika Hui Pū ʻIa, hiki iā ʻoe ke hālāwai me ka vincristine ma lalo o nā inoa e like me Oncovin, Vincasar PFS, a i ʻole ma ke ʻano he generic vincristine sulfate.

Loaʻa i kēia mau mana a pau ka mea hana like a hana like i kou kino. E hoʻohana kāu hale kūʻai lāʻau lapaʻau a i ʻole ke kikowaena lapaʻau i ka mana i loaʻa, a hiki iā ʻoe ke manaʻo i nā hopena therapeutic like me ka nānā ʻole i ka inoa inoa ma ka hue.

Nā koho ʻē aʻe o Vincristine

He nui nā lāʻau chemotherapy ʻē aʻe e hana like me ka vincristine a hiki ke hoʻohana ʻia ma ke ʻano he koho ʻē aʻe e pili ana i kou kūlana. No kēia mau koho ʻē aʻe i ka ʻohana lāʻau like a i ʻole nā ​​hana like i nā cella maʻi.

ʻO nā koho maʻamau e komo pū ana:

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• Vinblastine - kekahi vinca alkaloid me nā hopena like akā ʻokoʻa iki
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• Vinorelbine - he vinca alkaloid hou i hoʻohana pinepine ʻia no nā ʻano maʻi like ʻole
\n
• Paclitaxel - hana ma ka mahele cell akā ma o kahi hana ʻokoʻa
\n
• Docetaxel - like me paclitaxel me nā hopena like i ka mahele cell
\n

Koho kāu oncologist i ka lāʻau lapaʻau maikaʻi loa e pili ana i kāu ʻano maʻi kikoʻī, nā lāʻau lapaʻau i hala, a me nā mea pilikia pilikino. I kekahi manawa, pono ka hoʻololi ʻana i kahi koho ʻē aʻe inā loaʻa iā ʻoe nā hopena ʻaoʻao koʻikoʻi a i ʻole ʻaʻole pane maikaʻi kāu maʻi i ka vincristine.

Ua ʻoi aku ka maikaʻi o Vincristine ma mua o Vinblastine?

He mau lāʻau chemotherapy maikaʻi ʻo Vincristine a me vinblastine mai ka ʻohana like, akā ʻaʻole hiki ke hoʻololi pololei ʻia. Loaʻa i kēlā me kēia mea nā ikaika kikoʻī e kūpono ai no kekahi mau ʻano maʻi a me nā kūlana lapaʻau.

ʻOi aku ka maikaʻi o Vincristine i nā maʻi koko e like me ka leukemia a me ka lymphoma, ʻoiai ʻo vinblastine e hana maikaʻi pinepine no nā ʻōpū paʻa e like me ka maʻi testicular a me ka lymphoma o Hodgkin. ʻO ke koho ma waena o lākou e pili ana i kāu ʻano maʻi kikoʻī ma mua o ka mea i

Hiki ke hoʻohana palekana ʻia ʻo Vincristine i ka hapa nui o nā maʻi me ka maʻi diabetes, akā pono ka nānā pono ʻana a me ka hoʻopili ʻana ma waena o kāu oncologist a me ka hui mālama diabetes. ʻAʻole pili pololei ka lāʻau lapaʻau i nā pae kōpaʻa koko, akā hiki i kekahi mau hopena ʻaoʻao ke hoʻopilikia i kāu mālama diabetes.

Hiki i ka pōʻino o ke aʻalolo (neuropathy) i hiki i ka vincristine ke hana ke hoʻopili me ka diabetic neuropathy, e paʻakikī paha ka hoʻokaʻawale ʻana ma waena o nā kūlana ʻelua. E nānā pono kāu hui mālama ola iā ʻoe no ka ʻino ʻana o nā pilikia aʻalolo e kū nei a hoʻoponopono i kāu hoʻolālā lapaʻau inā pono.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o Vincristine?

He mea maʻamau loa ka overdose Vincristine no ka mea e helu pono nā poʻe loea mālama ola a nānā pālua i kēlā me kēia mahele ma mua o ka lawelawe ʻana. Eia naʻe, inā manaʻo ʻoe ua loaʻa ka overdose, e ʻimi koke i ka lāʻau lapaʻau ma ka lumi ulia pōpilikia kokoke loa a i ʻole e hoʻokaʻaʻike koke i kāu hui oncology.

ʻO nā hōʻailona o ka overdose e pili ana i ka nausea a me ka luaʻi nui, ka nāwaliwali loa, ka ʻeha aʻalolo nui, a i ʻole ka pilikia o ka hanu ʻana. ʻAʻohe lāʻau lapaʻau kikoʻī no ka overdose vincristine, no laila e kālele ana ka lapaʻau i ka mālama ʻana i nā hōʻailona a me ke kākoʻo ʻana i nā hana o kou kino a hiki i ka pau ʻana o ka lāʻau lapaʻau mai kāu ʻōnaehana.

He aha kaʻu e hana ai inā hala iaʻu kahi mahele o Vincristine?

Inā hala ʻoe i kahi lapaʻau vincristine i hoʻonohonoho ʻia, e hoʻokaʻaʻike koke i kāu hui oncology e hoʻonohonoho hou. Mai ho'āʻo e hoʻoponopono i ka mahele i hala ma ka lawe ʻana i ka lāʻau lapaʻau hou aʻe ma hope - hiki ke pilikia kēia a ʻaʻole ia ke ʻano o ka chemotherapy.

E hoʻoholo kāu hui mālama ola i ke ala maikaʻi loa e hoʻoponopono ai i kāu papa hana lapaʻau. I kekahi manawa hiki iā lākou ke hoʻomau me ka mahele i hoʻolālā ʻia aʻe, ʻoiai i nā manawa ʻē aʻe pono lākou e hoʻololi i kāu manawa lapaʻau holoʻokoʻa. Aia ka hoʻoholo i ka lōʻihi o kou hoʻopaneʻe ʻana i ka lapaʻau a me kahi āu i loko o kāu hoʻolālā lapaʻau holoʻokoʻa.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Vincristine?

Pono ʻoe e hooki i ka lawe ʻana i ka vincristine ke hoʻoholo kāu oncologist he palekana a kūpono ke hana pēlā. Hoʻokumu ʻia kēia hoʻoholo ma nā kumu he nui e like me ka maikaʻi o ka pane ʻana o kāu maʻi maʻi i ka lāʻau lapaʻau, kou kūlana olakino holoʻokoʻa, a inā paha ua hoʻopau ʻoe i ka papa hana i hoʻolālā ʻia.

Mai hooki i ka lāʻau lapaʻau vincristine ma kāu iho, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi a i ʻole e ʻike i nā hopena ʻaoʻao paʻakikī. ʻO ka hooki ʻana i ka wā mua e hiki ai i nā sela maʻi maʻi ke ulu hou a lilo paha i mea kūʻē i ka lāʻau lapaʻau. Inā koʻikoʻi nā hopena ʻaoʻao, hiki i kāu kauka ke hoʻoponopono i kāu mahele a i ʻole e hāʻawi i ka mālama kākoʻo hou e kōkua iā ʻoe e hoʻomau i ka lāʻau lapaʻau me ka palekana.

Hiki iaʻu ke kalaiwa ma hope o ka loaʻa ʻana o Vincristine?

Hiki i ka hapa nui o nā mea maʻi ke kalaiwa iā lākou iho i ka home ma hope o ka loaʻa ʻana o ka vincristine, no ka mea, he wikiwiki ke kaʻina hana infusion a ʻaʻole ia e hoʻoulu koke i ka hiamoe. Eia naʻe, pono ʻoe e pale i ke kalaiwa ʻana inā ʻike ʻoe i ka dizziness, ka luhi nui, a i ʻole nā ​​hoʻololi ʻike ma hope o ka lāʻau lapaʻau.

Ke holomua nei kāu lāʻau lapaʻau a ulu ka pōʻino o ke aʻalolo, e ʻike paha ʻoe e paʻakikī ke kalaiwa ʻana ma muli o ka emi ʻana o ka manaʻo i kou mau lima a me kou mau wāwae. E hoʻokumu mau i kou palekana a me ka palekana o nā poʻe ʻē aʻe ma ke alanui. Inā he hopohopo kāu e pili ana i kou hiki ke kalaiwa me ka palekana, e kūkākūkā i nā koho halihali ʻē aʻe me kāu hui mālama ola.