He aha ʻo Vinorelbine: Nā hoʻohana, ka nui o ka lāʻau, nā hopena ʻaoʻao a me nā mea hou aku

He lāʻau chemotherapy ʻo Vinorelbine i hāʻawi ʻia ma o ka laina IV (intravenous) e mālama i kekahi mau ʻano maʻi maʻi. No kēia lāʻau ikaika e hakakā nei i ka maʻi maʻi i kahi papa o nā lāʻau i kapa ʻia ʻo vinca alkaloids, e hana ana ma ka hoʻōki ʻana i nā cell maʻi maʻi mai ka mahele a me ka ulu ʻana.

Hiki iā ʻoe ke manaʻo nui i ka aʻo ʻana e pili ana i kahi lāʻau lapaʻau maʻi maʻi hou, a he mea maʻamau loa ia. ʻO ka hoʻomaopopo ʻana i ka hana ʻana o kēia lāʻau a me ka mea e manaʻo ai hiki ke kōkua iā ʻoe e mākaukau a hilinaʻi i kāu huakaʻi lapaʻau.

He aha ʻo Vinorelbine?

He lāʻau chemotherapy ʻo Vinorelbine e hoʻohana ai nā kauka e mālama i nā ʻano maʻi maʻi, ʻo ia hoʻi ka maʻi maʻi maʻi. He lāʻau semi-synthetic ia i loaʻa mai ka mea kanu periwinkle, i hoʻolālā ʻia e kuhikuhi a luku i nā cell maʻi ma kou kino.

Hele mai kēia lāʻau lapaʻau ma ke ʻano he wai maopopo, ʻaʻohe kala e hāʻawi ai nā poʻe loea mālama ola iā ʻoe ma o ke aʻa i kou lima a i ʻole ma o kahi laina waena. Hele ka lāʻau lapaʻau ma kou kahe koko e hiki i nā cell maʻi ma kahi e hiki ai i kou kino.

Ua manaʻo ʻia ʻo Vinorelbine he lāʻau chemotherapy ikaika. ʻOiai he mea maikaʻi ia i nā cell maʻi maʻi, ʻaʻole ia e like me kekahi mau lāʻau chemotherapy ʻē aʻe, ʻoiai pono nō ia i ka nānā pono ʻana e kāu hui lapaʻau.

No ke aha e hoʻohana ʻia ai ʻo Vinorelbine?

Hoʻomaʻamaʻa mua ʻo Vinorelbine i ka maʻi maʻi maʻi ʻole, ʻo ia ke ʻano maʻi maʻi maʻi maʻamau. Hiki i kāu kauka ke kauoha iā ia ke laha ka maʻi maʻi i nā ʻāpana ʻē aʻe o kou kino a i ʻole i ka wā i hana ʻole ai nā lāʻau lapaʻau ʻē aʻe e like me ka mea i manaʻo ʻia.

I kekahi manawa, hoʻohana nā kauka iā vinorelbine e mālama i nā ʻano maʻi maʻi ʻē aʻe. Hiki i kēia mau mea ke komo i ka maʻi maʻi umauma i laha, kekahi mau ʻano lymphoma, a i ʻole nā ​​tumora paʻa ʻē aʻe ke manaʻoʻiʻo kāu oncologist e hiki ke kōkua kēia lāʻau lapaʻau i kāu kūlana.

E noʻonoʻo ana kāu kauka i nā mea he nui i ka wā e hoʻoholo ai inā kūpono ka vinorelbine iā ʻoe. Pākuʻi ʻia kēia i ke ʻano a me ke kahua o kāu maʻi ʻaʻai, kou olakino holoʻokoʻa, a me ke ʻano o kou pane ʻana i nā lāʻau lapaʻau ʻē aʻe i ka wā ma mua.

Pehea e Hana ai ka Vinorelbine?

Hana ka vinorelbine ma ka hoʻopilikia ʻana i ka hiki o nā pūnaewele maʻi ʻaʻai ke māhele a hoʻonui. Hoʻopā ia i nā hale i kapa ʻia ʻo microtubules i loko o nā pūnaewele, e like me nā scaffolding liʻiliʻi e pono ai nā pūnaewele e māhele i ʻelua pūnaewele hou.

Ke hoʻopilikia ka vinorelbine i kēia mau microtubules, paʻa nā pūnaewele maʻi ʻaʻai i ke kaʻina o ka māhele ʻana a make hope. No ka mea e māhele wikiwiki ana nā pūnaewele maʻi ʻaʻai ma mua o ka hapa nui o nā pūnaewele maʻamau, pili kēia lāʻau lapaʻau iā lākou i ʻoi aku ka nui ma mua o nā pūnaewele olakino.

E holo ana ka lāʻau lapaʻau ma kou kino ma o kou kahe koko, e ʻae ana iā ia e hiki i nā pūnaewele maʻi ʻaʻai i hohola ʻia i nā ʻōkana like ʻole. ʻO kēia ala holoʻokoʻa ke kumu e kapa ai nā kauka he lāʻau

Aia ke ola o kāu lapaʻau vinorelbine ma ke ʻano o ka pane ʻana o kāu maʻi ʻaʻai a me ke ʻano o kou kino e ʻae ai i ka lāʻau. Loaʻa i ka hapa nui o nā kānaka nā lapaʻau i kēlā me kēia pule no kekahi mau pule, a ma hope e hoʻomaha e hoʻōla ai ko lākou kino.

E hoʻonohonoho kāu kauka i nā scans maʻamau a me nā hoʻokolohua koko e nānā i ke ʻano o ka pane ʻana o ka maʻi ʻaʻai i ka lapaʻau. Inā hana maikaʻi ka lāʻau a ke ʻae nei ʻoe iā ia, hiki iā ʻoe ke hoʻomau i ka lapaʻau no kekahi mau mahina.

I kekahi manawa, pono e hoʻomaha a i ʻole e hoʻōki i ka lapaʻau inā lilo nā hopena ʻaoʻao i mea paʻakikī loa a i ʻole inā pau ka pane ʻana o ka maʻi ʻaʻai. E hana pū kāu oncologist me ʻoe e ʻimi i ke kaulike kūpono ma waena o ka hakakā ʻana i ka maʻi ʻaʻai a me ka mālama ʻana i kou maikaʻi o ke ola.

He aha nā hopena ʻaoʻao o Vinorelbine?

E like me nā lāʻau chemotherapy a pau, hiki i ka vinorelbine ke hana i nā hopena ʻaoʻao, ʻoiai ʻaʻole i ʻike nā kānaka a pau iā lākou a pau. He kū hoʻokahi ka pane ʻana o kou kino i kēia lāʻau, a e nānā pono kāu hui mālama ola iā ʻoe i ka wā o ka lapaʻau.

E nānā kākou i nā hopena ʻaoʻao maʻamau e hiki iā ʻoe ke ʻike, me ka noʻonoʻo ʻana e hiki ke mālama ʻia ka nui o kēia mau mea me ka mālama kākoʻo a me nā lāʻau:

• Luhi a me ka nāwaliwali, e hoʻomaikaʻi pinepine ana ma waena o nā pōʻai lapaʻau
• Nausea a me ka luaʻi, hiki ke mālama ʻia me nā lāʻau anti-nausea
• Haʻahaʻa ke helu keʻokeʻo koko, hiki ke hoʻonui i ka pilikia o ka maʻi
• Ka nalowale o ka lauoho, maʻamau ka manawa a hiki ke hoʻohuli ʻia ma hope o ka pau ʻana o ka lapaʻau
• Paʻa ʻōpū, hiki i nā loli ʻai a me nā lāʻau ke kōkua
• ʻEha ʻiʻo a i ʻole hui e hoʻoponopono maʻamau i loko o kekahi mau lā
• Ka nalowale o ka ʻai, e hana ana i mea nui e ʻai i nā meaʻai liʻiliʻi a pinepine

Hiki ke mālama ʻia kēia mau hopena ʻaoʻao maʻamau me ke kākoʻo kūpono a me ka mālama ʻana mai kāu hui lapaʻau. ʻIke ka hapa nui o nā kānaka i ka ʻike ʻia ʻana o nā hopena ʻaoʻao i nā lā mua ma hope o ka lapaʻau, a laila e hoʻomaikaʻi mālie.

Hiki i kekahi poʻe ke ʻike i nā hopena ʻaoʻao koʻikoʻi e pono ai ka mālama olakino koke. ʻOiai ʻaʻole maʻamau kēia mau mea, he mea nui e ʻike i ka mea e nānā ai:

• Nā hōʻailona maʻi koʻikoʻi e like me ke kuni, nā anu, a i ʻole ka ʻū mau
• Ke kahe koko a i ʻole ka ʻeha ʻokoʻa ʻaʻole e ola maʻamau
• Ka pōkole o ka hanu a i ʻole ka pilikia o ka hanu
• Ka ʻeha a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae e ʻoi aku ka maikaʻi i ka manawa
• ʻEha nui a i ʻole ka pehu ʻana ma kahi o ka injection
• Nā hōʻailona o ka hopena maʻi e like me ka ʻōpala, ka pehu ʻana, a i ʻole ka pilikia o ka hanu

Pono kēia mau hopena ʻaoʻao koʻikoʻi i ka loiloi olakino wikiwiki, akā ʻaʻole maʻamau lākou ma mua o nā hopena ʻaoʻao hiki ke mālama ʻia i helu ʻia ma mua. E aʻo kāu hui mālama ola iā ʻoe i nā hōʻailona e nānā ai a i ka manawa e kelepona ai iā lākou.

ʻO wai ka mea ʻaʻole pono e lawe iā Vinorelbine?

ʻAʻole kūpono ʻo Vinorelbine no nā mea a pau, a e loiloi pono kāu kauka inā palekana ia iā ʻoe. ʻAʻole hiki i nā poʻe me nā ʻōnaehana pale maʻi i hoʻopilikia nui ʻia a i ʻole nā helu koko haʻahaʻa loa ke loaʻa i kēia lāʻau lapaʻau me ka palekana.

Inā loaʻa iā ʻoe kahi maʻi koʻikoʻi, makemake paha kāu kauka e mālama mua i kēlā ma mua o ka hoʻomaka ʻana iā vinorelbine. Hiki i kēia lāʻau lapaʻau ke hoʻonāwaliwali i kāu ʻōnaehana pale, e paʻakikī ai i kou kino ke pale aku i nā maʻi.

ʻAʻole hiki i nā poʻe me nā pilikia ate koʻikoʻi ke hana pono iā vinorelbine, e alakaʻi ana i nā hopena ʻaoʻao weliweli. E nānā kāu kauka i kāu hana ate me nā hoʻokolohua koko ma mua o ka hoʻomaka ʻana i ka mālama ʻana.

ʻAʻole pono nā wahine hāpai e loaʻa iā vinorelbine, no ka mea, hiki iā ia ke hōʻino i ka pēpē e ulu ana. Inā ʻoe i ka makahiki hānau keiki, e kūkākūkā kāu hui mālama ola i nā ʻano hana hoʻomalu hānau kūpono e hoʻohana ʻia i ka wā o ka mālama ʻana a no kekahi manawa ma hope.

Nā inoa inoa o Vinorelbine

Loaʻa ʻo Vinorelbine ma lalo o nā inoa inoa like ʻole, ʻo Navelbine ka mea i ʻike nui ʻia. Hiki i kāu hale kūʻai lāʻau a i ʻole ke kikowaena lapaʻau ke hoʻohana i ka inoa inoa a i ʻole e kāhea wale iā ia "vinorelbine."

ʻO nā inoa inoa ʻē aʻe e komo pū ana me Vinorelbine Ebewe a me nā ʻano generic like ʻole. He like ka lāʻau lapaʻau me ka nānā ʻole i ka inoa inoa, no laila, mai hopohopo inā ʻoe e ʻike i nā inoa like ʻole ma kāu palapala lapaʻau.

Hiki i kāu ʻinikua ke makemake i kekahi inoa inoa ma mua o kekahi, akā ʻaʻole kēia e pili i ka maikaʻi a i ʻole ka pono o kāu lapaʻau. E hana pū kāu hui mālama ola me kāu ʻinikua e hōʻoia e loaʻa iā ʻoe ka lāʻau lapaʻau āu e pono ai.

Nā Koho ʻē aʻe o Vinorelbine

Inā ʻaʻole ʻo vinorelbine ke koho kūpono iā ʻoe, aia kekahi mau lāʻau chemotherapy ʻē aʻe e hiki ke mālama i nā ʻano maʻi maʻi like. Hiki i kāu oncologist ke noʻonoʻo i nā lāʻau e like me paclitaxel, docetaxel, a i ʻole carboplatin, ma muli o kou kūlana.

I kekahi manawa, hoʻohana nā kauka i nā hui pū ʻana o nā lāʻau chemotherapy like ʻole, hiki ke ʻoi aku ka maikaʻi ma mua o nā lāʻau hoʻokahi. Hiki i kāu hoʻolālā lapaʻau ke komo pū me vinorelbine me nā lāʻau hakakā maʻi ʻē aʻe no ka pōmaikaʻi nui.

Loaʻa nō hoʻi nā lāʻau lapaʻau i manaʻo ʻia a me nā lāʻau immunotherapy hou no kekahi mau ʻano maʻi maʻi. E noʻonoʻo kāu kauka i nā ʻano kikoʻī o kāu maʻi maʻi, me nā hōʻailona genetic, e hoʻoholo ai i ke ala lapaʻau maikaʻi loa no ʻoe.

ʻOi aku ka maikaʻi o Vinorelbine ma mua o nā lāʻau lapaʻau maʻi maʻi maʻi ʻē aʻe?

Hāʻawi ʻo Vinorelbine i kekahi mau mea maikaʻi i hoʻohālikelike ʻia me kekahi mau lapaʻau maʻi maʻi maʻi ʻē aʻe, ʻoi aku hoʻi e pili ana i ka hiki ke ʻae ʻia. He nui ka poʻe i ʻike he maʻalahi ke mālama ʻia ma mua o nā regimens chemotherapy kahiko, me nā hopena ʻaoʻao liʻiliʻi.

I ka hoʻohālikelike ʻana me nā lāʻau lapaʻau e like me cisplatin, ʻo ka vinorelbine ke kumu pinepine i ka liʻiliʻi o ka nausea a me nā pilikia o ka puʻupaʻa. ʻAʻole hoʻi e hoʻopilikia i ka lohe ʻana a i ʻole ka pōʻino o nā aʻalolo, e lilo ana ia i koho maikaʻi no ka poʻe e makemake ana e mālama i ko lākou maikaʻi o ke ola i ka wā o ka mālama ʻana.

Eia naʻe, "ʻoi aku ka maikaʻi" e hilinaʻi loa ana i kou kūlana pilikino. Pane maikaʻi kekahi mau maʻi ʻaʻai i nā lāʻau lapaʻau ʻē aʻe, a ʻo kekahi poʻe e ʻae maikaʻi i nā lāʻau lapaʻau like ʻole. E noʻonoʻo kāu oncologist i nā mea he nui e koho i ka lāʻau lapaʻau kūpono loa no kāu hihia.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Vinorelbine

He Palekana anei ka Vinorelbine no ka poʻe me ka maʻi puʻuwai?

Hiki ke hoʻohana palekana ʻia ka Vinorelbine i ka poʻe me ka maʻi puʻuwai, akā pono kāu cardiologist a me ka oncologist e hana pū e nānā pono iā ʻoe. ʻAʻole paha e hoʻopilikia kēia lāʻau lapaʻau i nā pilikia o ka puʻuwai i hoʻohālikelike ʻia me kekahi mau lāʻau chemotherapy ʻē aʻe.

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, e kauoha paha kāu kauka i nā hoʻokolohua e nānā i ka maikaʻi o ka hana ʻana o kou puʻuwai. Hiki i kēia mau mea ke komo i ka electrocardiogram (EKG) a i ʻole echocardiogram e kiʻi i kahi ana kumu o kou olakino puʻuwai.

I ka wā o ka mālama ʻana, e nānā kāu hui lapaʻau i nā hōʻailona e hōʻike ana e pili ana ka lāʻau lapaʻau i kou puʻuwai. Inā loaʻa iā ʻoe nā maʻi puʻuwai, pono ʻoe i ka nānā pinepine ʻana, akā hiki i ka nui o ka poʻe me ka maʻi puʻuwai ke loaʻa i ka vinorelbine me ka palekana.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o ka Vinorelbine?

No ka mea, hāʻawi ʻia ka vinorelbine e nā poʻe loea mālama ola i kahi hoʻonohonoho i mālama ʻia, he mea maʻamau loa nā overdoses ulia pōpilikia. Hoʻohana kāu mau kahu hānai a me nā kauka i nā loiloi palekana he nui e hōʻoia e loaʻa iā ʻoe ka nui kūpono no kou nui kino a me ke kūlana.

Inā hopohopo ʻoe e pili ana i kāu mahele a i ʻole e ʻike i nā hōʻailona maʻamau ma hope o ka mālama ʻana, e hoʻokaʻaʻike koke i kāu hui mālama ola. Hiki iā lākou ke loiloi i kou kūlana a hāʻawi i ka mālama kūpono inā pono.

He mau hana i hoʻonohonoho ʻia e ke kikowaena lapaʻau no ka mālama ʻana i nā hewa lāʻau, ʻoiai e hana ana kēia mau ʻōnaehana palekana i nā hanana e like me kēia i mea maʻamau ʻole. Ua aʻo ʻia kāu hui lapaʻau e ʻike a mālama i nā pilikia e hiki ke kū mai.

He aha kaʻu e hana ai inā e hala wau i kahi lapaʻau Vinorelbine i hoʻonohonoho ʻia?

Inā pono ʻoe e hala i kahi lapaʻau vinorelbine i hoʻonohonoho ʻia, e hoʻokaʻaʻike i kāu hui oncology i ka wā hiki loa e hoʻonohonoho hou. E hana pū lākou me ʻoe e ʻimi i kahi manawa koho hou e kūpono i kāu papa manawa a mālama i ka pono o kāu hoʻolālā lapaʻau.

I kekahi manawa, pono paha ka hala ʻana i kahi lapaʻau inā ʻaʻole ʻoe e maikaʻi a i ʻole inā haʻahaʻa loa kāu helu koko. Hiki i kāu kauka ke hoʻopaneʻe i ka lapaʻau e hāʻawi i kou kino i ka manawa e ola ai, ʻo ia ka mea maʻamau i ke ala palekana.

Mai hoʻāʻo e hana i nā lapaʻau i hala ma ka hoʻonohonoho ʻana iā lākou i kahi kokoke. E hoʻoponopono kāu oncologist i kāu papa manawa lapaʻau e hōʻoia e loaʻa iā ʻoe ka mālama palekana a maikaʻi.

I ka manawa hea e hiki ai iaʻu ke hooki i ka lawe ʻana iā Vinorelbine?

Pono ʻoe e hooki i ka lapaʻau vinorelbine ma hope o ke kūkākūkā ʻana me kāu oncologist. Aia kēia hoʻoholo i ka maikaʻi o ka pane ʻana o kāu maʻi maʻi i ka lapaʻau a me ka maikaʻi o kou hoʻomanawanui ʻana i ka lāʻau.

E hoʻohana kāu kauka i nā scans maʻamau a me nā hoʻokolohua koko e nānā i kāu holomua. Inā e emi ana ka maʻi maʻi a i ʻole e paʻa ana, a ke mālama nei ʻoe i nā hopena ʻaoʻao, ʻo ka hoʻomau ʻana i ka lapaʻau ke koho maikaʻi loa.

I kekahi manawa, pono e hooki ʻia ka lapaʻau inā lilo nā hopena ʻaoʻao i mea koʻikoʻi loa a i ʻole inā ʻaʻole e pane hou ka maʻi maʻi i ka lāʻau. E kōkua kāu oncologist iā ʻoe e hoʻomaopopo i ka wā e kūpono ai ke hoʻololi i kahi ala lapaʻau ʻokoʻa.

Hiki iaʻu ke hana i ka wā e loaʻa ana iaʻu ka lapaʻau Vinorelbine?

Nui ka poʻe e hoʻomau i ka hana ʻoiai e loaʻa ana iā vinorelbine, ʻoiai pono paha ʻoe e hoʻoponopono i kāu papa manawa a i ʻole nā ​​kuleana. Hāʻawi ʻia ka lāʻau i kēlā me kēia pule, no laila pono ʻoe i ka manawa hoʻomaha no nā koho a me ka hoʻōla.

ʻO ka luhi kekahi o nā hopena ʻaoʻao maʻamau, no laila e ʻike paha ʻoe e pono ana ʻoe i ka hoʻomaha hou aʻe ma mua o ka maʻamau. E noʻonoʻo e kūkākūkā i nā hoʻonohonoho hana maʻalahi me kāu mea hana, e like me ka hana mai ka home i nā lā ke luhi nei ʻoe.

E hilinaʻi ana kou hiki ke hana i kāu pane pilikino i ka lāʻau lapaʻau, ke ʻano o ka hana āu e hana ai, a me kou olakino holoʻokoʻa. Nui ka poʻe i ʻike e hāʻawi ana ka hoʻolālā ʻana i nā lāʻau lapaʻau no nā Pōʻalima iā lākou i ka hopena pule e ola ai ma mua o ka hoʻi ʻana i ka hana.