He aha ka Lako Zoster (Shingrix): Nā Hoʻohana, ka Leka, nā hopena ʻaoʻao a me nā mea hou aku

ʻO ka lāʻau lapaʻau zoster, i ʻike nui ʻia ʻo Shingrix, he lāʻau lapaʻau maikaʻi loa ia e pale aku iā ʻoe mai ka shingles a me kāna mau pilikia. Hoʻohana kēia lāʻau lapaʻau recombinant i kahi ʻāpana liʻiliʻi o ka maʻi varicella-zoster i hui pū ʻia me kahi adjuvant e hoʻonui i kāu pane immune, e kōkua ana i kou kino e ʻike a hakakā i ka maʻi e hana ai i ka shingles.

Inā ʻoe ma luna o 50 a i ʻole he mau maʻi olakino e nāwaliwali ai kou ʻōnaehana immune, hiki i kēia lāʻau lapaʻau ke hōʻemi nui i kou pilikia o ka hoʻomohala ʻana i ka shingles ma mua o 90%. Ua manaʻo ʻia ʻo ia kekahi o nā lāʻau lapaʻau maikaʻi loa i loaʻa i kēia lā no ka pale ʻana i kēia maʻi ʻeha.

He aha ka Lako Zoster (Shingrix)?

ʻO Shingrix kahi lāʻau lapaʻau recombinant, adjuvanted i hoʻolālā ʻia e pale i ka shingles (herpes zoster) a me kāna mau pilikia. ʻAʻole like me nā lāʻau lapaʻau ola, aia kēia lāʻau lapaʻau i kahi protein liʻiliʻi mai ka maʻi varicella-zoster, ʻaʻole ka maʻi ola ponoʻī.

Aia i loko o ka lāʻau lapaʻau kahi adjuvant i kapa ʻia ʻo AS01B, e hana ana e like me ke kōkua e hoʻoikaika i kāu ʻōnaehana immune e pane ikaika i ka lāʻau lapaʻau. Hoʻokumu kēia hui i kahi pane immune ikaika e hiki ke pale iā ʻoe no nā makahiki he nui, ʻoiai e nāwaliwali ana kou ʻōnaehana immune me ka makahiki.

Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano he injection i loko o kou ʻiʻo lima luna a koi i ʻelua mau lāʻau i hoʻokaʻawale ʻia 2-6 mau mahina no ka pale piha.

No ke aha e hoʻohana ʻia ai ka Lako Zoster?

ʻO ke kumu nui o Shingrix ka pale ʻana i ka shingles, kahi maʻi ʻili ʻeha e ulu ana ke hoʻāla hou ʻia ka maʻi chickenpox i loko o kou kino. Paipai ʻia ka lāʻau lapaʻau no nā mākua 50 mau makahiki a ʻoi aku paha, me ka nānā ʻole inā hoʻomanaʻo lākou i ka loaʻa ʻana o ka chickenpox.

Ma waho aʻe o ka pale ʻana i ka maʻi shingles, pale pū ka lāʻau lapaʻau i ka postherpetic neuralgia (PHN), kahi pilikia koʻikoʻi e hoʻomau ai ka ʻeha o nā aʻalolo ma hope o ka pau ʻana o ka ʻōpala shingles. Hiki i kēia maʻi ʻeha mau ke mau i nā mahina a i ʻole nā makahiki, e hoʻopilikia nui ana i kou ola.

Paipai ʻia ka lāʻau lapaʻau no nā mākua 19 mau makahiki a ʻoi aku paha i nā ʻōnaehana pale i nāwaliwali ma muli o nā maʻi e like me ka HIV, nā lāʻau lapaʻau maʻi, a i ʻole nā mea hoʻololi kino. ʻOiai inā ua loaʻa iā ʻoe ka shingles ma mua, hiki i ka lāʻau lapaʻau ke kōkua i ka pale ʻana i nā hanana e hiki mai ana.

Pehea e hana ai ka Zoster Vaccine?

Hana ʻo Shingrix ma ka hoʻomaʻamaʻa ʻana i kou ʻōnaehana pale e ʻike a hakakā i ka maʻi varicella-zoster me ka ʻoi aku ka maikaʻi. Loaʻa i ka lāʻau lapaʻau kahi protein kikoʻī (glycoprotein E) mai ka maʻi e aʻo ai kou ʻōnaehana pale e ʻike he malihini.

Ke hui pū ʻia me ka adjuvant AS01B, hoʻomaka kēia protein i kahi pane pale ikaika e pili ana i nā antibodies a me nā T-cells. He mea nui kēia pale pālua no ka mea e emi ana ka palekana o ka T-cell me ka makahiki, ʻo ia ke kumu e ʻoi aku ai ka maʻalahi o nā mākua kahiko i ka shingles.

Manaʻo ʻia kēia lāʻau lapaʻau he ikaika loa a maikaʻi, e hāʻawi ana ma luna o 90% pale i ka shingles i nā hoʻokolohua lapaʻau. Noho kiʻekiʻe ka pale ʻana i nā poʻe ma luna o 70 mau makahiki, e hana ana i mea ʻoi aku ka maikaʻi ma mua o ka lāʻau lapaʻau zoster ola kahiko i ʻōlelo ʻole ʻia.

Pehea wau e lawe ai i ka Zoster Vaccine?

Hāʻawi ʻia ʻo Shingrix ma ke ʻano he injection i loko o ka ʻiʻo o kou lima luna e kekahi mea mālama ola. ʻAʻole pono ʻoe e lawe me ka meaʻai a i ʻole ka wai no ka mea he injection, ʻaʻole he lāʻau lapaʻau waha.

Pono ʻoe i ʻelua mau lāʻau o ka lāʻau lapaʻau, me ka lua o ka lāʻau i hāʻawi ʻia 2-6 mau mahina ma hope o ka lāʻau mua. He mea nui e hoʻopau i nā lāʻau ʻelua e hōʻoia i ka pale nui. Inā kali ʻoe ma mua o 6 mau mahina ma waena o nā lāʻau, ʻaʻole pono ʻoe e hoʻomaka hou i ka moʻo - e kiʻi wale i kāu lāʻau lua i ka hiki wawe.

Ma mua o kāu manawa kūkā, e ʻaʻahu i ka pālule me nā lima e hiki ke ʻōwili maʻalahi. Hiki iā ʻoe ke ʻai maʻamau ma mua a ma hope o kāu lāʻau lapaʻau, a ʻaʻohe kapu meaʻai kūikawā e pili ana i kēia lāʻau lapaʻau.

Pehea ka lōʻihi e lawe ai au i ka lāʻau lapaʻau Zoster?

ʻO ka lāʻau lapaʻau zoster he moʻo ʻelua-dose āu e hoʻopau ai i loko o kekahi mau mahina, ʻaʻole he lāʻau lapaʻau e lawe nei ʻoe i kēlā me kēia lā. Ke loaʻa iā ʻoe nā doses ʻelua, ua manaʻo ʻia ʻoe ua hoʻopaʻa ʻia i ka maʻi shingles.

Hōʻike ka noiʻi i kēia manawa e mau ana ka pale ʻana mai Shingrix no ka liʻiliʻi o 7 mau makahiki ma hope o ka lāʻau lapaʻau. Ke hana nei nā haʻawina e hoʻoholo pololei i ka lōʻihi o ka lōʻihi o ka pale ʻana, akā ʻaʻole pono ʻoe i nā pana booster no nā makahiki he nui, inā paha.

ʻAʻole like me kekahi mau lāʻau lapaʻau e koi ana i nā mea hoʻoikaika makahiki, ʻo ka pane immune ikaika i hana ʻia e Shingrix e hāʻawi i ka pale lōʻihi. E mālama kāu mea mālama ola iā ʻoe e pili ana i nā ʻōlelo aʻoaʻo e hiki mai ana no nā mea hoʻoikaika i ka wā e loaʻa ai ka noiʻi hou.

He aha nā hopena ʻaoʻao o ka lāʻau lapaʻau Zoster?

ʻO ka hapa nui o nā kānaka e ʻike i kekahi mau hopena ʻaoʻao maʻalahi a i ka waena ma hope o ka loaʻa ʻana o Shingrix, e hōʻike maoli ana e pane maikaʻi ana kāu ʻōnaehana immune i ka lāʻau lapaʻau. ʻO kēia mau hopena ʻaoʻao e mau ana ma kahi o 2-3 mau lā a hiki ke mālama ʻia me nā mea hōʻoluʻolu ʻeha ma luna o ka counter.

Eia nā hopena ʻaoʻao maʻamau āu e ʻike ai, ma ke kauoha mai ka mea nui a hiki i ka liʻiliʻi:

• ʻEha, ʻulaʻula, a i ʻole pehu ma kahi o ka injection (e pili ana i 8 mai 10 mau kānaka)
• ʻEha ʻiʻo a me ka luhi (e pili ana i 4-5 mai 10 mau kānaka)
• Poʻo (e pili ana i 4 mai 10 mau kānaka)
• Fiva a me nā anu (e pili ana i 2-3 mai 10 mau kānaka)
• Nausea a me ka ʻōpū (e pili ana i 1-2 mai 10 mau kānaka)

He ikaika pinepine kēia mau hopena ma hope o ka lua o ka mahele a he mea maʻamau ka ʻike ʻia ʻana i nā mākua ʻōpio. ʻOiai he mea hōʻoluʻolu ʻole, he mau hōʻailona lākou e kūkulu nei kāu ʻōnaehana pale i ka pale ʻana i ka shingles.

He mea maʻamau nā hopena ʻaoʻao koʻikoʻi akā hiki ke komo i nā hopena maʻi maʻi koʻikoʻi. Inā ʻike ʻoe i ka pilikia o ka hanu ʻana, ka pehu ʻana o kou maka a i ʻole ka ʻāʻī, a i ʻole nā hives koʻikoʻi, e ʻimi koke i ka lāʻau lapaʻau. Hiki i kekahi poʻe ke ʻike i ka ʻeha o ka poʻohiwi e pili ana i ka lawelawe ʻana i ka lāʻau lapaʻau (SIRVA), ʻoiai ʻaʻole maʻamau kēia ke hāʻawi pono ʻia ka injection.

ʻO wai ka mea ʻaʻole pono e lawe i ka Zoster Vaccine?

Hiki i ka hapa nui o nā mākua ke loaʻa palekana iā Shingrix, akā aia kekahi mau mea nui. ʻAʻole pono ʻoe e kiʻi i kēia lāʻau lapaʻau inā ua loaʻa iā ʻoe kahi hopena maʻi maʻi koʻikoʻi i kekahi mea o ka lāʻau lapaʻau a i ʻole i kahi mahele mua o Shingrix.

Pono ʻoe e pale i ka lāʻau lapaʻau inā e ʻike nei ʻoe i kahi maʻi maʻi maʻamau a koʻikoʻi me ke kuni. ʻOiai ʻaʻole e pale ka anu liʻiliʻi i ka lāʻau lapaʻau, ʻoi aku ka maikaʻi e kali a hiki i kou manaʻo maikaʻi e hōʻoia i hiki iā ʻoe ke loiloi pono i nā hopena ʻaoʻao e pili ana i ka lāʻau lapaʻau.

Inā hāpai ʻoe a i ʻole e hānai ana i ka umauma, pono ʻoe e kali e loaʻa iā Shingrix a hiki i ka pau ʻana o ka hāpai ʻana a me ka hānai ʻana i ka umauma. ʻOiai ʻaʻohe hōʻike o ka pōʻino, ʻaʻole lawa ka ʻikepili palekana i nā wahine hāpai e paipai i ka hoʻohana maʻamau.

Pono ka poʻe e lawe ana i kekahi mau lāʻau lapaʻau e kāohi nui ana i ka ʻōnaehana pale e kūkākūkā i ka manawa me kā lākou mea mālama ola. ʻOiai ua ʻōlelo ʻia ka lāʻau lapaʻau no nā poʻe immunocompromised, makemake paha kāu kauka e hoʻoponopono i ka manawa ma muli o kāu papa hana lapaʻau.

Zoster Vaccine Brand Names

ʻO Shingrix ka inoa inoa no ka recombinant zoster vaccine i hana ʻia e GlaxoSmithKline (GSK). ʻO kēia ka lāʻau lapaʻau zoster wale nō i ʻōlelo ʻia e ka CDC no nā mākua 50 a ʻoi aku.

Hiki paha iā ʻoe ke lohe e pili ana iā Zostavax, ʻo ia ka lāʻau lapaʻau ola kahiko, akā ʻaʻole i loaʻa hou ma ʻAmelika Hui Pū ʻia mai ka makahiki 2020. Inā ua loaʻa iā ʻoe ʻo Zostavax i ka wā ma mua, pono nō ʻoe e kiʻi iā Shingrix no ka pale maikaʻi.

I ka wā e hoʻonohonoho ai i kāu manawa, e noi wale i ka

He lōʻihi nō hoʻi ka pale ʻana mai Shingrix. ʻOiai ua emi nui ka pono o Zostavax ma hope o 5 mau makahiki, mālama ʻo Shingrix i ka pono kiʻekiʻe no ka liʻiliʻi o 7 mau makahiki a ʻoi aku paha. ʻO kēia pale ʻana i ʻoi aku ka maikaʻi a me ka lōʻihi ke kumu i hoʻololi ai nā luna olakino iā Zostavax me Shingrix.

ʻOiai inā ua loaʻa iā ʻoe ʻo Zostavax i ka wā ma mua, pono nō ʻoe e kiʻi iā Shingrix no ka pale maikaʻi. Hiki iā ʻoe ke loaʻa iā Shingrix i kēlā me kēia manawa ma hope o ka loaʻa ʻana o Zostavax – ʻaʻohe manawa kali i koi ʻia.

Nā Nīnau i Nīnau Pinepine ʻia e pili ana i ka Lāʻau Lapaʻau Zoster

He Palekana ʻo Shingrix no ka poʻe me ka maʻi diabetes?

ʻAe, palekana ʻo Shingrix a he mea nui loa ia no ka poʻe me ka maʻi diabetes. Hiki i ka maʻi diabetes ke hoʻonāwali i kāu ʻōnaehana pale, e hoʻonui ana iā ʻoe i ka maʻi shingles a me kāna mau pilikia.

Hiki i ka poʻe me ka maʻi diabetes i loaʻa i ka shingles ke ʻike i nā hōʻailona ʻoi aku ka nui a me nā manawa hoʻōla lōʻihi. Hāʻawi ka lāʻau lapaʻau i ka pale maikaʻi like i ka poʻe me ka maʻi diabetes e like me ka poʻe me ka ʻole, e hana ana i ka lāʻau lapaʻau i mea pale maikaʻi. ʻAʻole pono e hoʻopilikia nui ʻia kāu pae kō koko e ka lāʻau lapaʻau, akā makemake paha ʻoe e nānā pono iā lākou no kekahi mau lā ma hope o ka lāʻau lapaʻau inā loaʻa iā ʻoe ka mana glucose paʻa.

He aha kaʻu e hana ai inā loaʻa iaʻu ka nui o nā lāʻau o Shingrix?

Inā loaʻa iā ʻoe kahi lāʻau hou o Shingrix, mai hopohopo – ʻaʻole kēia e hōʻeha nui. E hoʻokaʻaʻike i kāu mea mālama ola e hōʻike i ka lāʻau hou a kūkākūkā i nā hopohopo.

Hiki iā ʻoe ke ʻike i nā hopena ʻaoʻao ʻoi aku ka ikaika ma mua o ka maʻamau, e like me ka piʻi ʻana o ka ʻeha ma ke kahua injection a i ʻole nā hōʻailona like me ka maʻi flu. Pono e hoʻoponopono ʻia kēia mau mea i loko o kekahi mau lā. E mālama i ka manawa i loaʻa iā ʻoe i kēlā me kēia lāʻau e hōʻoia i ka hoʻokaʻawale pono ʻana o nā lāʻau lapaʻau e hiki mai ana. Hiki i kāu mea mālama ola ke kōkua iā ʻoe e hoʻoholo inā pono e hana i nā hoʻoponopono i kāu papa hana lāʻau lapaʻau.

He aha kaʻu e hana ai inā e poina iaʻu kaʻu lāʻau ʻelua o Shingrix?

Inā ʻoe e hala i kāu mahele lua o Shingrix, e hoʻonohonoho iā ia i ka wā hiki wawe. ʻAʻole pono ʻoe e hoʻomaka hou i ka moʻo - e kiʻi wale i kāu mahele lua i ka wā e hiki ai iā ʻoe, ʻoiai inā ua hala ma mua o 6 mau mahina mai kāu mahele mua.

ʻOiai ʻo ka manawa i ʻōlelo ʻia he 2-6 mau mahina ma waena o nā mahele, ʻo ka loaʻa ʻana o ka mahele lua ma hope o ka mea i hoʻolālā ʻia ʻaʻole ia e hōʻemi i kona pono. E pane maikaʻi nō kāu ʻōnaehana pale i ka mahele lua i hoʻopaneʻe ʻia. Eia naʻe, ʻaʻole ʻoe e loaʻa ka pale piha ʻana mai ka shingles a hiki i kou hoʻopau ʻana i nā mahele ʻelua, no laila, mai hoʻopaneʻe me ka pono ʻole.

I ka manawa hea e hiki ai iaʻu ke hooki i ka hopohopo e pili ana i ka Shingles ma hope o ka loaʻa ʻana o Shingrix?

Hiki iā ʻoe ke manaʻoʻiʻo e pili ana i kāu pale ʻana i ka shingles ma kahi o 2-4 mau pule ma hope o ka loaʻa ʻana o kāu mahele lua o Shingrix. ʻO kēia ka manawa i pane piha ai kāu ʻōnaehana pale i ka lāʻau lapaʻau a kūkulu i ka pale kiʻekiʻe.

Hāʻawi ka lāʻau lapaʻau ma luna o 90% ka pale, ʻo ia hoʻi, e lilo ana kou pilikia o ka hoʻomohala ʻana i ka shingles i mea haʻahaʻa loa. Eia naʻe, e hoʻomanaʻo ʻaʻole he 100% pono ka lāʻau lapaʻau, no laila, aia nō kahi mea liʻiliʻi o ka shingles. Inā ʻoe e hoʻomohala i ka shingles ma hope o ka lāʻau lapaʻau, e ʻoi aku ka maʻalahi a me ka pōkole ma mua o ka mea i loaʻa me ka ʻole o ka lāʻau lapaʻau.

Hiki iaʻu ke kiʻi iā Shingrix inā e lawe ana au i nā mea lahilahi koko?

ʻAe, hiki iā ʻoe ke loaʻa palekana iā Shingrix inā e lawe ana ʻoe i nā mea lahilahi koko e like me warfarin, apixaban, a i ʻole aspirin. Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano he injection intramuscular, a ʻoiai aia paha ka ʻeha liʻiliʻi ma ke kahua injection, ʻaʻole kēia he mea weliweli.

E hōʻike i kāu mea mālama ola e pili ana i kāu mau lāʻau lahilahi koko ma mua o ka lāʻau lapaʻau. Hiki iā lākou ke hoʻopili i ke kaomi i ke kahua injection no ka manawa lōʻihi ma mua o ka maʻamau e hōʻemi i ka ʻeha. ʻOi aku ka maikaʻi o ka pale ʻana i ka shingles ma mua o ka pilikia liʻiliʻi o ka hoʻonui ʻia ʻana o ka ʻeha, ʻoiai ʻo ka poʻe ma nā mea lahilahi koko e ʻoi aku ka pilikia o nā pilikia shingles.